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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:radiculopathy
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Accession:DOID:4306 term browser browse the term
Definition:A peripheral nervous system disease that is characterized by the pinching of a nerve root in the spine and has symptoms of pain, weakness, numbness and tingling. (DO)
Synonyms:exact_synonym: Cervical Radiculopathy;   Nerve Root Avulsion;   Nerve Root Compression;   Nerve Root Compressions;   Nerve Root Disorder;   Nerve Root Disorders;   Nerve Root Inflammation;   Nerve Root Inflammations;   Radiculitides;   cervical radiculopathies;   nerve root avulsions;   pinched nerve;   radiculitis;   radiculopathies
 primary_id: MESH:D011843
 xref: ICD10CM:M54.1
For additional species annotation, visit the Alliance of Genome Resources.


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radiculopathy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO mRNA:increased expression:spinal cord RGD PMID:17401154 RGD:2289993 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:14513263 RGD:1581324 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Tnf tumor necrosis factor ISO mRNA:increased expression:spinal cord, dorsal root ganglion RGD PMID:18848809 RGD:7394750 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18301
    disease of anatomical entity 15631
      nervous system disease 13500
        peripheral nervous system disease 4114
          radiculopathy 3
            polyradiculopathy 0
paths to the root