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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:radiculopathy
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Accession:DOID:4306 term browser browse the term
Definition:Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root.
Synonyms:exact_synonym: Cervical Radiculopathy;   Nerve Root Avulsion;   Nerve Root Avulsions;   Nerve Root Compression;   Nerve Root Compressions;   Nerve Root Disorder;   Nerve Root Disorders;   Nerve Root Inflammation;   Nerve Root Inflammations;   Radiculitides;   Radiculitis;   cervical radiculopathies;   pinched nerve;   radiculopathies
 primary_id: MESH:D011843
 xref: ICD10CM:M54.1
For additional species annotation, visit the Alliance of Genome Resources.


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radiculopathy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEP mRNA:increased expression:spinal cord RGD PMID:17401154 RGD:2289993 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:14513263 RGD:1581324 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tnf tumor necrosis factor IEP mRNA:increased expression:spinal cord, dorsal root ganglion RGD PMID:18848809 RGD:7394750 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        peripheral nervous system disease 2500
          radiculopathy 3
            polyradiculopathy 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.