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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:glucose metabolism disease
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Accession:DOID:4194 term browser browse the term
Definition:Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM.
Synonyms:exact_synonym: Glucose Metabolic Disorder;   Glucose Metabolic Disorders;   Glucose Metabolism Disorder;   Glucose Metabolism Disorders;   disorder of glucose metabolism
 primary_id: MESH:D044882;   RDO:0002537
 xref: NCI:C53655
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
glucose metabolism disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100511376 E3 SUMO-protein ligase RanBP2 ISO RGD PMID:17069463 RGD:9835347 NCBI chr 3:47,531,362...47,601,328
Ensembl chr 3:47,531,358...47,601,379
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29802709 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,937...144,956,095
JBrowse link
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO OMIM NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,385,512...101,443,405
JBrowse link
G PHGDH phosphoglycerate dehydrogenase ISO ClinVar Annotator: match by term: MITOCHONDRIAL HMG-CoA SYNTHASE DEFICIENCY ClinVar NCBI chr 4:101,445,977...101,478,144
Ensembl chr 4:101,408,308...101,478,144
JBrowse link
abdominal obesity-metabolic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15309680 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:23320128 RGD:7241841 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,961,909
JBrowse link
abdominal obesity-metabolic syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:increased oxidation:cardiac muscle cell RGD PMID:23997093 RGD:13782087 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,973
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,187,260...54,228,144
JBrowse link
G FADD Fas associated via death domain treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,186,744...3,194,792
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:30172001 RGD:13792561 NCBI chr14:100,927,305...100,954,781 JBrowse link
G KDSR 3-ketodihydrosphingosine reductase treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G LPL lipoprotein lipase treatment ISO RGD PMID:26996629 RGD:13794382 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814
JBrowse link
G MTTP microsomal triglyceride transfer protein ISO OMIM NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,819,142...120,879,388
JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO RGD PMID:19841034 RGD:15090861 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
abdominal obesity-metabolic syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHDC1 AT-hook DNA binding motif containing 1 ISO ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 ClinVar PMID:25741868 NCBI chr 6:84,735,253...84,774,554 JBrowse link
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B ISO OMIM NCBI chr 6:48,305,837...48,314,523
Ensembl chr 6:48,305,844...48,314,886
JBrowse link
adrenocorticotropic hormone deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE65 retinoid isomerohydrolase RPE65 ISO ClinVar Annotator: match by term: Adrenocorticotropic hormone deficiency ClinVar PMID:9326941 PMID:9501220 PMID:9843205 PMID:18632300 PMID:25741868 More... NCBI chr 6:144,206,078...144,229,471
Ensembl chr 6:144,206,077...144,293,709
JBrowse link
G TBX19 T-box transcription factor 19 ISO OMIM NCBI chr 4:82,663,121...82,699,261
Ensembl chr 4:82,663,581...82,697,813
JBrowse link
autosomal dominant Wolfram syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WFS1 wolframin ER transmembrane glycoprotein ISO OMIM NCBI chr 8:4,362,678...4,405,185
Ensembl chr 8:4,362,678...4,385,272
JBrowse link
background diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin treatment ISO RGD PMID:10848441 RGD:10046010 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,438,017...62,485,537
JBrowse link
G CAT catalase ISO associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO protein:decreased expression:aqueous humor: RGD PMID:23853629 RGD:10402120 NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,620,700...5,795,264
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:decreased expression:vitreous: RGD PMID:19799585 RGD:10449447 Ensembl chr 5:8,986,461...9,007,446 JBrowse link
carnitine palmitoyltransferase I deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPT1A carnitine palmitoyltransferase 1A ISO OMIM NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,984
JBrowse link
Carnitine Palmitoyltransferase II Deficiency, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPT2 carnitine palmitoyltransferase 2 ISO OMIM NCBI chr 6:159,038,129...159,061,327
Ensembl chr 6:159,036,821...159,061,327
JBrowse link
cataract 47 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC16A12 solute carrier family 16 member 12 ISO OMIM NCBI chr14:101,273,977...101,368,350
Ensembl chr14:101,273,993...101,368,152
JBrowse link
Childhood-Onset Spasticity with Hyperglycinemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 ISO OMIM NCBI chr 7:116,787,346...116,797,477
Ensembl chr 7:116,787,432...116,800,554
JBrowse link
chromosome 17q11.2 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF135 ring finger protein 135 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: VAN ASPEREN SYNDROME
ClinVar Annotator: match by term: Macrocephaly, macrosomia, facial dysmorphism syndrome
CTD
ClinVar
PMID:17632510 PMID:21681106 PMID:25741868 PMID:27535533 PMID:28135719 More... NCBI chr12:42,793,755...42,808,937
Ensembl chr12:42,790,187...42,808,919
JBrowse link
Cleft Palate, Proliferative Retinopathy, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRC32 leucine rich repeat containing 32 ISO OMIM NCBI chr 9:10,802,228...10,815,892
Ensembl chr 9:10,801,946...10,817,930
JBrowse link
Combined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 ISO OMIM NCBI chr11:65,230,145...65,299,084
Ensembl chr11:65,230,162...65,303,844
JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus ClinVar PMID:2256350 PMID:22563501 PMID:24220513 PMID:32214227 PMID:33983693 NCBI chr 6:146,990,115...147,161,010
Ensembl chr 6:146,989,325...147,155,132
JBrowse link
Congenital Hyperinsulinism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO DNA:mutations:exon:multiple
ClinVar Annotator: match by term: Familial hyperinsulinism
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy
ClinVar Annotator: match by term: familial hyperinsulinism
DNA:deletion: :p.S1387del (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:exon:p.G1485E (c.4454G>A), p.D1506E (c.4518C>A), p.M1544K (c.4541T>A) (human)
DNA:mutations:exon, intron:multiple
DNA:missense mutations, nonsense mutations, splice-site mutations:CDS:multiple
RGD
ClinVar
CTD
PMID:7716548 PMID:8751851 PMID:8923011 PMID:9041101 PMID:9536098 More... RGD:11067821 RGD:11069847 RGD:11070657 RGD:12743628 RGD:12790587 RGD:12790596 RGD:12790723 RGD:704365 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620
JBrowse link
G COMMD6 COMM domain containing 6 ISO RGD PMID:19470471 RGD:7248544 NCBI chr11:47,795,110...47,818,543
Ensembl chr11:47,543,814...47,818,561
JBrowse link
G GLUD1 glutamate dehydrogenase 1 ISO DNA:missense mutations: : RGD PMID:9571255 RGD:1302513 NCBI chr14:87,968,850...88,005,375
Ensembl chr14:87,968,850...88,005,550
JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO DNA:deletion:cds (human) RGD PMID:14693719 RGD:2306664 NCBI chr 8:113,952,561...114,005,510
Ensembl chr 8:113,950,033...114,005,512
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO DNA:mutations: :
ClinVar Annotator: match by term: Familial hyperinsulinism
RGD
ClinVar
PMID:10227563 PMID:10447526 PMID:10768098 PMID:10983627 PMID:15281001 More... RGD:12904701 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO DNA:missense mutation:exon:p.R34H (c.101G>A) (human)
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, frameshift mutations:CDS:multiple
DNA:deletion, insertion:exon
DNA:deletion, frameshift mutation, missense mutations:exon:multiple
DNA:SNPs:exon:c.151G>T, c.1017G>T (human)
RGD
ClinVar
CTD
PMID:9867219 PMID:11318841 PMID:11872696 PMID:12196481 PMID:12475776 More... RGD:11069847 RGD:12743624 RGD:12743643 RGD:12790587 RGD:12790723 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555
JBrowse link
G KCNT2 potassium sodium-activated channel subfamily T member 2 ISO ClinVar Annotator: match by term: KCNT2-related condition ClinVar PMID:29069600
G UCP2 uncoupling protein 2 ISO ClinVar Annotator: match by term: Familial hyperinsulinism ClinVar PMID:25741868 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,333,153...8,365,558
JBrowse link
Developmental Delay, Epilepsy, and Neonatal Diabetes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO ClinVar Annotator: match by term: DEND syndrome ClinVar PMID:25741868 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555
JBrowse link
Diabetes Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr11:64,089,149...64,309,831 JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25304492 PMID:25541468 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:20479236 RGD:7241550 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:20479236 RGD:7241550 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,543...117,472,003
JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24252320 RGD:13782355 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,515...74,730,092
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO Associated with obesity RGD PMID:21282363 RGD:6906933 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO protein: decreased expression: serum RGD PMID:18025762 RGD:7242563 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,316,436...66,452,917
JBrowse link
G GLO1 glyoxalase I no_association ISO DNA:SNP: :419C>A (human) RGD PMID:21738003 RGD:7242569 NCBI chr 7:34,156,194...34,183,560
Ensembl chr 7:34,068,806...34,183,528
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HP haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19769483 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G MIR140 microRNA mir-140 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32062618 NCBI chr 6:17,077,530...17,077,599
Ensembl chr 6:17,077,507...17,077,620
JBrowse link
G MUC1 mucin 1, cell surface associated ISO associated with Diabetes Mellitus, Experimental RGD PMID:23977093 RGD:7349380 NCBI chr 4:94,626,317...94,631,194 JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 6:84,225,670...84,228,156
Ensembl chr 6:84,225,694...84,228,094
JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:diaphragm RGD PMID:23443767 RGD:7327179 NCBI chr 1:43,449,354...43,458,925 JBrowse link
G PON1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19003935 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21548839 RGD:6484542 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,321...25,783,610
JBrowse link
G SLC10A2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr11:71,328,801...71,348,779
Ensembl chr11:71,327,016...71,348,779
JBrowse link
G SLC51A solute carrier family 51 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr13:133,851,775...133,869,753
Ensembl chr13:133,851,776...133,869,753
JBrowse link
G SLC51B solute carrier family 51 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 1:163,081,145...163,089,491
Ensembl chr 1:163,081,180...163,089,488
JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18057998 RGD:6771339 NCBI chr 6:84,373,921...84,426,447
Ensembl chr 6:84,372,649...84,426,997
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
diabetes mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:9618169 PMID:9648840 PMID:10204114 PMID:14692646 PMID:14715863 More... NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620
JBrowse link
G ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 ISO protein:increased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr 8:130,853,414...130,945,388
Ensembl chr 8:130,775,472...130,998,660
JBrowse link
G ACP1 acid phosphatase 1 ISO RGD PMID:8620937 RGD:2313188 NCBI chr 3:132,671,408...132,684,793
Ensembl chr 3:132,667,045...132,684,674
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18378355 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,189...124,401,739
JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:23396398 RGD:7243186 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22831748 PMID:25741868 PMID:26336158 PMID:28492532
G ALDOB aldolase, fructose-bisphosphate B ISO mRNA:reduced expression:pancreatic islet (mouse) RGD PMID:11904435 RGD:2313440 NCBI chr 1:243,127,870...243,141,504
Ensembl chr 1:243,110,585...243,141,418
JBrowse link
G ALMS1 ALMS1 centrosome and basal body associated protein ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18154657 PMID:21157496 PMID:21943378 PMID:22876109 PMID:24033266 More... NCBI chr 3:69,253,742...69,417,043
Ensembl chr 3:69,253,748...69,417,397
JBrowse link
G ALPK1 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 8:110,241,220...110,368,001
Ensembl chr 8:110,241,619...110,367,993
JBrowse link
G APOB apolipoprotein B ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200
JBrowse link
G APOC2 apolipoprotein C2 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 6:51,404,219...51,406,302 JBrowse link
G APOC3 apolipoprotein C3 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 9:44,211,171...44,213,538 JBrowse link
G APOE apolipoprotein E treatment ISO RGD PMID:17192461 RGD:1601230 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G APOH apolipoprotein H ISO mRNA:increased expression:retina
protein:increased expression:plasma
RGD PMID:9377806 PMID:18695102 RGD:2313982 RGD:2313991 NCBI chr12:12,827,195...12,839,172
Ensembl chr12:12,827,201...12,839,175
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO protein:altered localization:retina RGD PMID:19748503 RGD:2316076 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,481...42,076,746
JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:19748503 RGD:2316076 NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,400,794...111,422,042
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 ISO associated with Obesity, Morbid;mRNA:decreased expression:omentum, adipose tissue (human) RGD PMID:26504501 RGD:11049459 NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,150...31,826,855
JBrowse link
G ASIP agouti signaling protein ISO CTD Direct Evidence: marker/mechanism
associated with Obesity;DNA:mutation (mouse)
CTD
RGD
PMID:1473152 PMID:10426381 RGD:2314006 NCBI chr17:37,542,615...37,718,787 JBrowse link
G ATP6 ATP synthase F0 subunit 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18273840 NCBI chr MT:9,120...9,800
Ensembl chr MT:9,120...9,800
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:19667185 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:23430896 PMID:23963299 PMID:25588603 PMID:25741868 PMID:26467025 More... NCBI chr 2:9,052,676...9,064,890
Ensembl chr 2:9,052,070...9,064,888
JBrowse link
G CASP3 caspase 3 ISO protein:increased expression:ovary RGD PMID:28412870 RGD:40400904 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11117918 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CAV1 caveolin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CAVIN1 caveolae associated protein 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr12:20,372,476...20,390,250
Ensembl chr12:20,372,476...20,390,242
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:serum RGD PMID:18385799 RGD:2307062 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CD36 CD36 molecule ISO protein:increased expression:macrophage RGD PMID:17551591 RGD:2307209 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G CD40LG CD40 ligand ISO associated with Coronary Arteriosclerosis, Myocardial Infarction; protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 ISO DNA:snp: :rs10946398(human) RGD PMID:19741467 RGD:2313940 NCBI chr 7:15,910,645...16,569,643
Ensembl chr 7:15,910,666...16,685,053
JBrowse link
G CEL carboxyl ester lipase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 1:272,763,203...272,770,259
Ensembl chr 1:272,763,226...272,770,255
JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12572680 NCBI chr13:89,396,713...89,463,540
Ensembl chr13:89,396,685...89,463,538
JBrowse link
G CPB2 carboxypeptidase B2 ISO protein:increased expression, increased activity:plasma RGD PMID:14983223 RGD:2313643 NCBI chr11:21,234,447...21,298,250
Ensembl chr11:21,234,447...21,298,244
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233164 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,984
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO associated with hepatocellular��carcinoma;DNA:hypermethylation:promoter (human) RGD PMID:32724427 RGD:150524282 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,138...151,147,634
JBrowse link
G CTSB cathepsin B onset ISO DNA:transversion:cds:p.L26V (human) RGD PMID:18706099 RGD:2315528 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,034,737
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23307960 RGD:9491759 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 ISO DNA:polymorphisms:5' utr, cds:-344C>T, p.K173R (human) RGD PMID:11687612 RGD:2307297 NCBI chr 4:1,365,725...1,373,138 JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO associated with Smoking Inhalation Injury; DNA:polymorphism:3' UTR:5639T>C (human) RGD PMID:11996959 RGD:2307073 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,780,105...58,809,755
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO mRNA,protein:decreased expression:liver RGD PMID:10876162 RGD:41412168 NCBI chr 9:72,057,506...72,079,587
Ensembl chr 9:72,057,511...72,079,444
JBrowse link
G DICER1 dicer 1, ribonuclease III ISO RGD PMID:22216196 RGD:149735536 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,361,630...116,436,519
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,875...57,506,247
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:decreased expression:urine
protein:increased expression:plasma
RGD PMID:8914465 PMID:9212353 RGD:11060253 RGD:2313869 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,992...122,837,672
JBrowse link
G F7 coagulation factor VII no_association ISO protein:increased activity:plasma (rat) RGD PMID:10899350 PMID:10910004 PMID:15258325 RGD:1598920 RGD:2312391 RGD:2312393 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,158...78,518,671
JBrowse link
G FN1 fibronectin 1 ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11213886 PMID:20551625 RGD:7206845 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G FOXP3 forkhead box P3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G FUCA1 alpha-L-fucosidase 1 ISO protein:decreased activity:blood platelets RGD PMID:3609421 RGD:2315945 NCBI chr 6:81,638,213...81,655,993
Ensembl chr 6:81,637,989...81,723,231
JBrowse link
G FXN frataxin ISO DNA:deletion:exon (mouse) RGD PMID:12925693 RGD:2307048 NCBI chr 1:222,412,485...222,433,224
Ensembl chr 1:222,412,500...222,461,943
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO protein:decreased activity:blood RGD PMID:24865682 RGD:10449112 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G GAD1 glutamate decarboxylase 1 ISO RGD PMID:1924335 RGD:728511 NCBI chr15:76,991,863...77,034,819
Ensembl chr15:76,991,928...77,034,817
JBrowse link
G GATA6 GATA binding protein 6 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:20581743 PMID:22158542 PMID:23223019 PMID:24310933 More... NCBI chr 6:107,282,709...107,314,725
Ensembl chr 6:107,282,847...107,314,634
JBrowse link
G GC GC vitamin D binding protein ISO protein:increased expression:ascitic fluid RGD PMID:20054029 RGD:5509921 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,301...68,360,262
JBrowse link
G GIPR gastric inhibitory polypeptide receptor ISO human gene, mouse model RGD PMID:15582721 RGD:2312617 NCBI chr 6:52,022,667...52,033,959
Ensembl chr 6:52,022,681...52,033,954
JBrowse link
G GLIS3 GLIS family zinc finger 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 1:217,572,604...218,117,629
Ensembl chr 1:217,629,331...218,117,267
JBrowse link
G GLUD1 glutamate dehydrogenase 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr14:87,968,850...88,005,375
Ensembl chr14:87,968,850...88,005,550
JBrowse link
G GNB3 G protein subunit beta 3 no_association ISO DNA:polymorphism: :multiple (human) RGD PMID:16908025 RGD:2313206 NCBI chr 5:63,863,656...63,871,352
Ensembl chr 5:63,863,661...63,870,433
JBrowse link
G GP91-PHOX NADPH oxidase heavy chain subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,642,015...33,680,580
JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:skeletal muscle (mouse) RGD PMID:18562625 PMID:18936159 RGD:2312632 RGD:2312633 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GSR glutathione-disulfide reductase ISO protein:decreased activity:blood: RGD PMID:22540111 RGD:7257584 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989
JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22662265 PMID:25741868 PMID:27104957 PMID:28492532 NCBI chr 8:113,952,561...114,005,510
Ensembl chr 8:113,950,033...114,005,512
JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,768,741
JBrowse link
G HGF hepatocyte growth factor ISO mRNA, protein:increased expression:cornea RGD PMID:16186340 RGD:2313569 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,437,087...98,513,156
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:15476492 RGD:2313755 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,225...84,402,956
JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:8945470 PMID:9032114 PMID:9112026 PMID:9133564 PMID:9166684 More... NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328
JBrowse link
G HNF1B HNF1 homeobox B ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15930087 PMID:16249435 PMID:18065799 PMID:19639018 PMID:20633866 More... NCBI chr12:39,143,119...39,201,631
Ensembl chr12:39,143,121...39,313,511
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:10983627 PMID:16946562 PMID:18414213 PMID:24033266 PMID:25741868 More... NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G HP haptoglobin ISO RGD PMID:12540619 RGD:1626347 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G ICA1 islet cell autoantigen 1 ISO RGD PMID:7918678 RGD:633043 NCBI chr 9:78,364,478...78,515,092
Ensembl chr 9:78,332,374...78,515,087
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:19394054 RGD:2313467 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA,protein:decreased expression:corpus cavernosum: RGD PMID:22133301 RGD:10046054 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:16642022 RGD:2311506 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,925...137,690,666
JBrowse link
G IL10 interleukin 10 ISO RGD PMID:22802947 RGD:7364853 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:18503494 RGD:2311530 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,552...65,001,173
JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:serum,ovary RGD PMID:28412870 RGD:40400904 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL6 interleukin 6 susceptibility ISO protein:increased expression:extracellular space (human)
associated with Dementia; protein:increased expression:brain (human)
mRNA:decreased expression:dendritic cell (mouse)
DNA:polymorphism:promoter:-174G>C (human)
RGD PMID:18689695 PMID:19120268 PMID:19139294 PMID:19442860 RGD:2307180 RGD:2307273 RGD:2307278 RGD:2307293 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G INS insulin ISO DNA, protein:missense mutations, altered processing:exons, endoplasmic reticulum:multiple
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
protein:altered localization :endoplasmic reticulum
CTD Direct Evidence: marker/mechanism|therapeutic
DNA, protein:missense mutations:exons:multiple
DNA:point mutation (mouse)
RGD
ClinVar
CTD
PMID:2055425 PMID:7294224 PMID:7624867 PMID:8400068 PMID:11446671 More... RGD:2311109 RGD:2311115 RGD:2317259 RGD:2317260 RGD:2317262 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G INSR insulin receptor ISO DNA:deletions, missense mutation:multiple (human)
ClinVar Annotator: match by term: Monogenic diabetes
RGD
ClinVar
PMID:2040394 PMID:2211730 PMID:2983222 PMID:8257688 PMID:8432414 More... RGD:2307343 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,139
JBrowse link
G IRS1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10591678 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,308,335
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO protein:increased expression:monocyte (human) RGD PMID:17466965 RGD:2307424 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 susceptibility ISO DNA:deletion:exon:p.Q1715_R1731del (mouse) RGD PMID:21565852 RGD:6480678 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,908
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO Diabetes Mellitus, permanent neonatal, OMIM:606176
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
DNA:mutation: :p.V59M (mouse)
RGD
ClinVar
PMID:8897013 PMID:10338089 PMID:12524280 PMID:14715863 PMID:15115830 More... RGD:1625256 RGD:2311536 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555
JBrowse link
G KIF1A kinesin family member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr15:139,610,624...139,694,841
Ensembl chr15:139,610,626...139,694,826
JBrowse link
G KIF5B kinesin family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr10:42,637,105...42,693,551
Ensembl chr10:42,637,109...42,693,491
JBrowse link
G KLF11 Kruppel like factor 11 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15774581 PMID:17130512 PMID:18414213 PMID:18593768 PMID:19122346 More... NCBI chr 3:126,419,011...126,429,890
Ensembl chr 3:126,418,996...126,429,904
JBrowse link
G LEP leptin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,447
JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:15028607 PMID:25741868 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,798,979...146,896,108
JBrowse link
G LMNA lamin A/C ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2007407 PMID:2270059 PMID:2526018 PMID:10587585 PMID:10655060 More... NCBI chr 4:93,899,019...93,927,255
Ensembl chr 4:93,899,026...93,949,398
JBrowse link
G LOC100622980 cytochrome b5 reductase 4 ISO RGD PMID:15247412 RGD:2315644 NCBI chr 1:53,092,006...53,191,216
Ensembl chr 1:53,091,419...53,191,212
JBrowse link
G LOC110256000 membrane primary amine oxidase-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr12:19,996,324...20,007,006 JBrowse link
G LRP1 LDL receptor related protein 1 treatment ISO RGD PMID:22889684 RGD:13800521 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G MAFA MAF bZIP transcription factor A treatment ISO RGD PMID:23801580 RGD:13506744 NCBI chr 4:1,090,018...1,093,600
Ensembl chr 4:1,091,263...1,092,818
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16731828 NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,495
JBrowse link
G MARCO macrophage receptor with collagenous structure ISO protein:decreased expression:Alveolar macrophage RGD PMID:27630197 RGD:41412199 NCBI chr15:24,502,935...24,541,286
Ensembl chr15:24,503,108...24,541,353
JBrowse link
G MC4R melanocortin 4 receptor ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:9267995 PMID:10078568 PMID:10199800 PMID:10592235 PMID:10903341 More... NCBI chr 1:160,772,013...160,774,124
Ensembl chr 1:160,772,013...160,774,124
JBrowse link
G MT-2B metallothionein-2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,059...18,646,033
JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association ISO DNA:transition:cds:g.677C>T (human) RGD PMID:9607212 RGD:38501049 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 3:11,820,367...11,834,394
Ensembl chr 3:11,820,285...11,839,426
JBrowse link
G ND4L NADH dehydrogenase subunit 4L ISO DNA:deletion: :m.8213_13992 (human) RGD PMID:7603516 RGD:5686343 NCBI chr MT:11,069...11,365
Ensembl chr MT:11,069...11,365
JBrowse link
G NEUROD1 neuronal differentiation 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr15:87,175,629...87,179,953
Ensembl chr15:87,175,764...87,179,961
JBrowse link
G NPPB natriuretic peptide B onset ISO RGD PMID:23733199 RGD:7246907 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO mRNA:increased expression:pancreatic islet RGD PMID:17259388 RGD:2311606 NCBI chr 6:84,225,670...84,228,156
Ensembl chr 6:84,225,694...84,228,094
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr13:140,373,571...140,406,129
Ensembl chr13:140,364,075...140,406,112
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,450
JBrowse link
G PAX4 paired box 4 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr18:20,675,874...20,680,315
Ensembl chr18:20,673,167...20,680,287
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO mRNA, decreased expression:pancreatic islet (mouse)
ClinVar Annotator: match by term: Monogenic diabetes
RGD
ClinVar
PMID:10545530 PMID:10545531 PMID:10720084 PMID:11022198 PMID:11270685 More... RGD:2308812 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,639...5,310,843
JBrowse link
G PLIN1 perilipin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,235,426...55,250,797
JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19153526 NCBI chr 3:113,661,712...113,668,558 JBrowse link
G PON1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16229851 PMID:19022366 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:16168052 PMID:19748282 PMID:25741868 PMID:27749844 PMID:28492532 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
G PPP1R3A protein phosphatase 1 regulatory subunit 3A ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:12118251 PMID:25741868 PMID:28492532 NCBI chr18:31,997,667...32,039,949
Ensembl chr18:31,997,713...32,039,853
JBrowse link
G PROM1 prominin 1 ISO RGD PMID:11237753 RGD:68837 NCBI chr 8:11,215,659...11,331,442
Ensembl chr 8:11,215,659...11,317,312
JBrowse link
G PTEN phosphatase and tensin homolog ISO protein:increased expression, increased phosphorylation:inferior vena cava RGD PMID:16961925 RGD:2292543 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTF1A pancreas associated transcription factor 1a ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:25775927 PMID:28492532 NCBI chr10:51,817,697...51,820,147
Ensembl chr10:51,818,388...51,819,761
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:15885672 RGD:5143927 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp: cds: C1858T RGD PMID:18764813 RGD:6484729 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G RAC1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687
JBrowse link
G RFX6 regulatory factor X6 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15592663 PMID:18414213 PMID:20148032 PMID:25741868 PMID:28492532 More... NCBI chr 1:44,765,451...44,826,884
Ensembl chr 1:44,765,450...44,823,516
JBrowse link
G SERPINA7 serpin family A member 7 ISO RGD PMID:8742570 RGD:2312329 NCBI chr  X:86,708,624...86,714,324
Ensembl chr  X:86,708,632...86,714,330
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO RGD PMID:10910004 RGD:2312393 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SHBG sex hormone binding globulin ISO protein:increased expression:plasma RGD PMID:18346991 RGD:2313784 NCBI chr12:52,914,711...52,919,092 JBrowse link
G SHLD2 shieldin complex subunit 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr14:88,005,599...88,121,155
Ensembl chr14:88,005,590...88,121,383
JBrowse link
G SIM1 SIM bHLH transcription factor 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2152513 PMID:16924270 PMID:21512513 PMID:23778136 PMID:23778139 More... NCBI chr 1:67,213,685...67,294,455
Ensembl chr 1:67,214,337...67,294,397
JBrowse link
G SIRT1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894401 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G SLC19A2 solute carrier family 19 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes RGD
ClinVar
PMID:10391221 PMID:25741868 PMID:28492532 RGD:1599325 NCBI chr 4:81,510,221...81,535,099
Ensembl chr 4:81,510,079...81,536,466
JBrowse link
G SLC22A12 solute carrier family 22 member 12 ISO protein:decreased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr 2:7,557,822...7,565,801
Ensembl chr 2:7,557,827...7,565,895
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO RGD PMID:10022440 RGD:12879500 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SLC2A2 solute carrier family 2 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:8027028 PMID:8063045 PMID:11810292 PMID:23986439 PMID:25741868 More... NCBI chr13:109,592,595...109,614,105
Ensembl chr13:109,587,256...109,623,787
JBrowse link
G SLC2A3 solute carrier family 2 member 3 ISO RGD PMID:10086067 RGD:2313619 NCBI chr 5:62,963,635...63,041,955 JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ameliorates ISO RGD PMID:15100317 RGD:151232286 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,969
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23786522 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G SOD3 superoxide dismutase 3 ISO RGD PMID:12830380 RGD:1581299 NCBI chr 8:18,796,633...18,802,156
Ensembl chr 8:18,796,636...18,802,154
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:10835640 PMID:15980664 PMID:16849362 PMID:18978175 PMID:23017645 More... NCBI chr 2:149,072,652...149,079,529
Ensembl chr 2:149,071,703...149,079,499
JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 ISO RGD PMID:12749121 RGD:1600067 NCBI chr 3:107,840,200...107,918,351
Ensembl chr 3:107,839,964...107,918,350
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO associated with Cystic Fibrosis;DNA:SNP (human) RGD PMID:19585101 RGD:2312417 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,694...123,546,417
JBrowse link
G TFPI tissue factor pathway inhibitor ISO protein:increased expression:plasma: RGD PMID:8914465 RGD:11060253 NCBI chr15:92,345,083...92,409,962
Ensembl chr15:92,345,075...92,409,905
JBrowse link
G THBS2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 1:854,473...882,467
Ensembl chr 1:855,030...882,473
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO protein:decreased expression:glomerulus RGD PMID:19506087 RGD:2312464 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,297
JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:monocyte RGD PMID:15632890 PMID:19210958 RGD:1580736 RGD:2312485 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO RGD PMID:10192335 RGD:2312735 NCBI chr 6:72,103,309...72,174,882 JBrowse link
G UCP3 uncoupling protein 3 ISO RGD PMID:17587402 RGD:2313514 NCBI chr 9:8,378,023...8,389,452
Ensembl chr 9:8,378,019...8,386,211
JBrowse link
G VDR vitamin D receptor no_association ISO DNA:SNPs: :rs731236, rs1544410, rs7975232 (human) RGD PMID:22856230 RGD:8158070 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,267,321
JBrowse link
G VWF von Willebrand factor treatment ISO RGD PMID:19722571 RGD:7207029 NCBI chr 5:64,516,627...64,655,938
Ensembl chr 5:64,519,186...65,002,098
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein onset ISO DNA:missense mutations:cds:p.R456H, p.R611H (rs1801206, rs1801214) (human)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
RGD
ClinVar
PMID:10521293 PMID:10624825 PMID:10679252 PMID:11161832 PMID:11244483 More... RGD:149735331 RGD:8694404 NCBI chr 8:4,362,678...4,405,185
Ensembl chr 8:4,362,678...4,385,272
JBrowse link
G ZFP57 ZFP57 zinc finger protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:18414213 PMID:18622393 PMID:23748067 PMID:25741868 PMID:28492532 NCBI chr 7:22,607,420...22,612,064
Ensembl chr 7:22,605,125...22,612,064
JBrowse link
Diabetes Mellitus, Congenital Autoimmune term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12930356 NCBI chr 1:255,436,206...255,459,020
Ensembl chr 1:255,432,969...255,459,073
JBrowse link
Diabetes Mellitus, New-Onset after Transplantation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:22645144 RGD:10040997 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
diabetic angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO OMIM NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ADCY3 adenylate cyclase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 3:113,875,005...113,969,053
Ensembl chr 3:113,875,512...113,988,372
JBrowse link
G ADCY8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,644,589...9,866,534
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372816 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19733855 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304
JBrowse link
G ASS1 argininosuccinate synthase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25033204 NCBI chr 1:270,531,434...270,586,364
Ensembl chr 1:270,531,589...270,586,361
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15878326 RGD:7241570 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410
JBrowse link
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23154660 RGD:11526153 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CD28 CD28 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased expression:T cell RGD PMID:15504310 RGD:2307197 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,208...107,162,943
JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:serum RGD PMID:14963650 RGD:2314223 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CREM cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr10:57,829,523...57,895,610
Ensembl chr10:57,829,518...57,895,610
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 susceptibility ISO associated with Diabetic Foot;DNA:polymorphism:3' utr (human) RGD PMID:16723689 RGD:2306558 NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,429...91,552,766
JBrowse link
G EPO erythropoietin ISO OMIM NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936
JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
protein:increased expression:plasma
RGD PMID:9285207 PMID:16371118 RGD:2313861 RGD:2313868 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,992...122,837,672
JBrowse link
G FAS Fas cell surface death receptor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15803113 RGD:2315753 NCBI chr14:100,927,305...100,954,781 JBrowse link
G FASLG Fas ligand ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD
RGD
PMID:15803113 PMID:25381014 RGD:2315753 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,475
JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:12716757 RGD:1601179 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha ISO RGD PMID:21411989 RGD:7242686 NCBI chr12:51,975,810...51,979,428
Ensembl chr12:51,975,874...51,977,757
JBrowse link
G GPX1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G GSR glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989
JBrowse link
G HFE homeostatic iron regulator ISO OMIM NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,768,741
JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16959961
G HP haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta
RGD PMID:18093596 PMID:18796303 RGD:2306988 RGD:2313473 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr18:50,018,487...50,022,799
Ensembl chr18:50,018,487...50,022,799
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO OMIM
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:12477149 RGD:1582581 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,174,500...76,185,923
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16681562 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G NOS2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea RGD PMID:19241604 PMID:19587355 RGD:2313210 RGD:4891384 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea
CTD
RGD
PMID:12124201 PMID:19241604 PMID:29329611 RGD:13504708 RGD:4891384 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased tyrosine phosphorylation:conceptus RGD PMID:10329590 RGD:2311657 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,582,481...14,723,336
JBrowse link
G PLAT plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:18945481 RGD:2311663 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032
JBrowse link
G POLR1C RNA polymerase I and III subunit C ISO ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar PMID:11978667 NCBI chr 7:38,511,521...38,531,938
Ensembl chr 7:38,507,073...38,537,943
JBrowse link
G PON1 paraoxonase 1 ISO OMIM NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PTK2B protein tyrosine kinase 2 beta treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21926342 RGD:10041069 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,194
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G SERPINE1 serpin family E member 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:deletion, haplotype:promoter:g.-676_-674delG (human) RGD PMID:9844142 RGD:8547700 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SERPINF1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G SOD1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G SOD2 superoxide dismutase 2 ISO OMIM NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,651,280...7,691,723
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:mesentery, blood vessel RGD PMID:10625572 RGD:2300063 NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,703...71,381,160
JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,781...131,746,115
JBrowse link
G THBS2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 1:854,473...882,467
Ensembl chr 1:855,030...882,473
JBrowse link
G TNF tumor necrosis factor susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:c.-308G>A (human) RGD PMID:18575614 RGD:2313255 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G VEGFA vascular endothelial growth factor A ISO OMIM NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
Diabetic Cardiomyopathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21742475 RGD:10046044 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,438,017...62,485,537
JBrowse link
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr  X:12,099,849...12,152,204
Ensembl chr  X:12,099,853...12,151,275
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental;
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:heart (rat)
RGD PMID:23251674 RGD:7244283 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29353218 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15587404 PMID:16025228 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388
JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:18332268 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16685413 PMID:21441944 RGD:6771209 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,973
JBrowse link
G ATP7A ATPase copper transporting alpha treatment ISO RGD PMID:24927960 RGD:11341676 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,874...62,110,058
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21296063 RGD:10053697 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,515...74,730,092
JBrowse link
G CASQ2 calsequestrin 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21441944 RGD:6771209 NCBI chr 4:104,918,204...104,984,019
Ensembl chr 4:104,918,501...104,999,787
JBrowse link
G CASR calcium sensing receptor ISO protein:decreased expression:myocardium (rat) RGD PMID:22137362 RGD:7205677 NCBI chr13:138,279,785...138,364,934
Ensembl chr13:138,280,363...138,364,253
JBrowse link
G CFL1 cofilin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:27576917 RGD:11568692 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CTNNB1 catenin beta 1 ISO mRNA,protein:increased expression:heart RGD PMID:25586361 RGD:13524855 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,137,173...25,208,311
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,973,037...114,696,375
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23453443 PMID:23853776 RGD:10412713 RGD:9586347
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11375343 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23843977 RGD:7247697 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G INS insulin ISO CTD Direct Evidence: therapeutic CTD PMID:20828608 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase treatment ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:myocardium (mouse) RGD PMID:21296063 PMID:21474815 RGD:10053697 RGD:11522727 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G KLK1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16129698 NCBI chr 6:55,570,632...55,576,398
Ensembl chr 6:55,570,630...55,576,637
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MYLK2 myosin light chain kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:9005973 RGD:1580244 NCBI chr17:35,499,828...35,513,096
Ensembl chr17:35,499,908...35,513,088
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23353773 PMID:23453443 RGD:10412713 RGD:10412721 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29274332 RGD:13504685 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G NPPA natriuretic peptide A treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23497378 RGD:7297056 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G NRG1 neuregulin 1 ISO associated with Diabetes Mellitus, Experimental;protein:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,627,334...53,688,332
JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:heart left ventricle RGD PMID:22185592 RGD:7327207 NCBI chr 1:43,449,354...43,458,925 JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO Strain: ZDF RGD PMID:19317897 RGD:5509944 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G RYR2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685413 NCBI chr14:53,652,140...54,406,691
Ensembl chr14:53,652,245...54,406,355
JBrowse link
G SLC25A4 solute carrier family 25 member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:18945756 NCBI chr15:46,193,498...46,197,989
Ensembl chr15:46,193,699...46,200,994
JBrowse link
G SLC8A1 solute carrier family 8 member A1 treatment ISO RGD PMID:27058979 RGD:13628396 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,245,140
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16980342 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
G TERT telomerase reverse transcriptase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21264070 RGD:11038677 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909696 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23843977 RGD:7247697 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,986,528...108,080,151
JBrowse link
diabetic cataract term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSR glutathione-disulfide reductase ISO RGD PMID:12518238 RGD:10401829 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989
JBrowse link
Diabetic Cystopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nuclei: RGD PMID:20879002 RGD:10053565 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,519...106,708,317
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23129268 RGD:10053664 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
Diabetic Embryopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain ISO RGD PMID:26419589 RGD:13792560 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,186,744...3,194,792
JBrowse link
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23529380 PMID:24291733 RGD:7244255 RGD:8553040 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G APP amyloid beta precursor protein treatment ISO associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,434,869...189,716,057
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574
JBrowse link
G IDE insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr14:103,992,035...104,106,571
Ensembl chr14:103,992,037...104,106,576
JBrowse link
G NGF nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr 4:105,256,691...105,307,843
Ensembl chr 4:105,256,417...105,307,842
JBrowse link
G NGFR nerve growth factor receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr12:25,699,410...25,720,355
Ensembl chr12:25,699,427...25,720,357
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
Diabetic Foot term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:plasma RGD PMID:20836881 RGD:5686889 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO associated with Diabetes Mellitus, Type 2;protein:decreased expression:blood RGD PMID:21941211 RGD:6767555 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G CRP C-reactive protein, pentraxin-related disease_progression ISO protein:increased expression:blood: RGD PMID:22712631 RGD:6906887 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G GJA1 gap junction protein alpha 1 ISO protein:increased expression:dermis RGD PMID:22455314 RGD:7207269 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,515...41,002,137
JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:fibroblast of dermis,stratum basale of epidermis: RGD PMID:10727985 RGD:8549356 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL15 interleukin 15 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:dermis, endothelial cell RGD PMID:17014667 RGD:2313575 NCBI chr 8:85,666,963...85,740,980
Ensembl chr 8:85,667,307...85,740,911
JBrowse link
G MBL2 mannose binding lectin 2 ISO protein:increased expression:serum: RGD PMID:19997692 RGD:8694068 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,894...97,108,936
JBrowse link
G MMP9 matrix metallopeptidase 9 severity ISO RGD PMID:22688339 RGD:8547813 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G PLAT plasminogen activator, tissue type ISO RGD PMID:17275886 RGD:2311669 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032
JBrowse link
G PTX3 pentraxin 3 ISO protein:decreased expression:plasma (human) RGD PMID:30767386 RGD:38501100 NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:SNPs,haplotype: :rs4986790,rs4986791,rs10759931,rs1927911(human); RGD PMID:23936790 RGD:7777174 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
diabetic ketoacidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP2 aquaporin 2 ISO RGD PMID:12021537 RGD:2314345 NCBI chr 5:15,862,739...15,868,565
Ensembl chr 5:15,863,303...15,868,565
JBrowse link
G INS insulin ISO CTD Direct Evidence: therapeutic CTD PMID:11430560 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G INSR insulin receptor ISO RGD PMID:15254588 RGD:1302526 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,139
JBrowse link
G PAX4 paired box 4 susceptibility ISO ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone, susceptibility to OMIM
ClinVar
PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr18:20,675,874...20,680,315
Ensembl chr18:20,673,167...20,680,287
JBrowse link
G SERPINA7 serpin family A member 7 ISO protein:decreased expression:serum RGD PMID:6768790 RGD:2312332 NCBI chr  X:86,708,624...86,714,324
Ensembl chr  X:86,708,632...86,714,330
JBrowse link
Diabetic Nephropathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 no_association
susceptibility
treatment
ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Diabetes Mellitus, Type 1;DNA:insertion/deletion
associated with Diabetes Mellitus, Type 2;DNA:insertion/deletion
associated with Diabetes Mellitus, Experimental
RGD
CTD
PMID:7729604 PMID:7909524 PMID:8314010 PMID:10099885 PMID:10857950 More... RGD:11039044 RGD:2311449 RGD:7829777 RGD:7829780 RGD:8548872 RGD:8548885 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ACE2 angiotensin converting enzyme 2 no_association ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple (human)
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:decreased expression:kidney
mRNA, protein:altered expression:kidney
RGD
CTD
PMID:12623933 PMID:17600118 PMID:18235039 PMID:19034303 PMID:19077419 More... RGD:2313796 RGD:2313797 RGD:2313800 NCBI chr  X:12,099,849...12,152,204
Ensembl chr  X:12,099,853...12,151,275
JBrowse link
G ACVR1 activin A receptor type 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:11675415 RGD:2313802 NCBI chr15:64,749,478...64,891,653
Ensembl chr15:64,748,761...64,892,153
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing no_association
disease_progression
ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1501299 (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs2241766 (human)
protein:increased expression:plasma
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
CTD
RGD
PMID:17942768 PMID:17970779 PMID:21945031 PMID:23260797 RGD:5686409 RGD:8694443 RGD:8694475 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G ADORA1 adenosine A1 receptor ISO associated with Diabetes Mellitus, Experimental RGD PMID:19552053 RGD:2313803 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,920...113,875,719
JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism (human) RGD PMID:15660746 RGD:2313545 NCBI chr 3:45,760,966...45,762,306
Ensembl chr 3:45,758,268...45,764,178
JBrowse link
G ADRB3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9867224 RGD:5684403 NCBI chr15:48,468,803...48,478,370 JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
susceptibility
ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney cortex, glomerulus
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1704G>T (human)
associated with Diabetes Mellitus;DNA:polymorphisms, haplotype:cds, intron:p.G82S, g.2184A>G (rs2070600, rs3134940) (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD PMID:12651605 PMID:14747204 PMID:19142024 PMID:21533139 PMID:21856399 More... RGD:2325651 RGD:7243248 RGD:7243852 RGD:7244174 RGD:7244187 RGD:8695982 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AGT angiotensinogen no_association
disease_progression
ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :p.M235T (human)
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)
CTD
RGD
PMID:8772723 PMID:10862638 PMID:11938025 PMID:17890855 PMID:19014923 More... RGD:11039058 RGD:8548868 RGD:8548872 RGD:8548885 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1166A>C (human)
associated with Diabetes Mellitus, Experimental
RGD PMID:12172324 PMID:12476891 RGD:6903861 RGD:8548891 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,131
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:18565281 RGD:6903847 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388
JBrowse link
G AHSG alpha 2-HS glycoprotein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15698447 RGD:2313813 NCBI chr13:124,426,313...124,438,848
Ensembl chr13:124,426,308...124,438,840
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:promoter:repeat:g.?(AC)n (human) RGD PMID:9000706 PMID:9215310 RGD:734542 RGD:8548641 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G ALB albumin ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
associated with Metabolic Syndrome X;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16380483 PMID:19246226 PMID:19397971 PMID:19424163 PMID:21441310 RGD:2306882 RGD:2306885 RGD:2306886 RGD:5135032 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304
JBrowse link
G ALPK1 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 8:110,241,220...110,368,001
Ensembl chr 8:110,241,619...110,367,993
JBrowse link
G APOA1 apolipoprotein A1 ISO RGD PMID:9829487 RGD:2313960 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APOA2 apolipoprotein A2 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:9829487 PMID:11126402 RGD:2313958 RGD:2313960 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
G APOB apolipoprotein B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19324028 RGD:2313979 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200
JBrowse link
G APOC3 apolipoprotein C3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-455T>C RGD PMID:16813599 RGD:2306755 NCBI chr 9:44,211,171...44,213,538 JBrowse link
G APOE apolipoprotein E susceptibility
no_association
ISO associated with Diabetes Mellitus, Experimental
DNA:missense mutations, haplotype:cds:p.C112R, p.R158C (human)
associated with Diabetes Mellitus, type 1;
RGD PMID:11495633 PMID:21127830 PMID:22859852 RGD:6902935 RGD:6903840 RGD:7771553 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G APOH apolipoprotein H ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:11302005 RGD:2313989 NCBI chr12:12,827,195...12,839,172
Ensembl chr12:12,827,201...12,839,175
JBrowse link
G AQP2 aquaporin 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased secretion:urine RGD PMID:12218327 RGD:2314343 NCBI chr 5:15,862,739...15,868,565
Ensembl chr 5:15,863,303...15,868,565
JBrowse link
G ARG2 arginase 2 ISO RGD PMID:21926276 RGD:6902923 NCBI chr 7:91,343,987...91,385,911
Ensembl chr 7:91,343,987...91,385,911
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta treatment ISO mRNA:decreased expression:renal glomerulus (rat) RGD PMID:22591908 RGD:13792578 NCBI chr 5:21,984,750...21,992,393
Ensembl chr 5:21,984,580...21,992,407
JBrowse link
G AXL AXL receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 NCBI chr 6:49,245,802...49,277,917
Ensembl chr 6:49,245,673...49,277,914
JBrowse link
G AZIN1 antizyme inhibitor 1 treatment ISO RGD PMID:26751697 RGD:14700801 NCBI chr 4:34,221,368...34,257,261
Ensembl chr 4:34,209,008...34,257,136
JBrowse link
G BDKRB2 bradykinin receptor B2 susceptibility ISO associated with Diabetes Mellitus, Experimental RGD PMID:17596525 RGD:2313335 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,543...117,472,003
JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:20557422 RGD:4891134 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:kidney RGD PMID:21866636 RGD:6483069 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO RGD PMID:17437042 RGD:2289036 NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,091...57,676,944
JBrowse link
G C3 complement C3 ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:kidney:
associated with Diabetes Mellitus, Type 2
RGD PMID:19200691 PMID:25662584 RGD:11040807 RGD:7183082 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,499...72,528,112
JBrowse link
G C5 complement C5 ISO associated with Diabetes Mellitus, Type 2 RGD PMID:25662584 RGD:11040807 NCBI chr 1:260,995,662...261,088,868
Ensembl chr 1:260,995,662...261,133,483
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B treatment ISO RGD PMID:27273361 RGD:13506726
G CAPN10 calpain 10 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22012129 RGD:7247733 NCBI chr15:139,557,643...139,568,764
Ensembl chr15:139,557,666...139,570,181
JBrowse link
G CASP3 caspase 3 treatment ISO associated with Diabetes Mellitus, Experimental;protein:increased activity:kidney
associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:19601660 PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 RGD:2311440 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CASP7 caspase 7 treatment ISO associated with type 2 diabetes mellitus RGD PMID:28456626 RGD:13782304 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,018,568...124,050,366
JBrowse link
G CASP8 caspase 8 treatment ISO associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29606028 PMID:30038056 RGD:13782342 RGD:13792586 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,515...74,730,092
JBrowse link
G CAT catalase ISO rat gene in db/db mice
associated with experimentally induced diabetes
RGD PMID:20299359 PMID:21525431 PMID:21686137 PMID:22315314 RGD:7205651 RGD:7205662 RGD:7205665 RGD:7205676 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CCL11 chemokine (C-C motif) ligand 11 ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21113841 RGD:5683918 NCBI chr12:40,779,906...40,782,862
Ensembl chr12:40,779,173...40,782,893
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 disease_progression
susceptibility
ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16374426 PMID:17968528 PMID:18031723 PMID:19097668 PMID:19369290 More... RGD:2306979 RGD:2306980 RGD:2306982 RGD:2306989 RGD:2306991 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17664181 RGD:7483629 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-28C>G
RGD PMID:12610055 PMID:18326229 RGD:2307063 RGD:2307107 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CCN2 cellular communication network factor 2 ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney, glomerulus (rat)
RGD PMID:19065061 PMID:19895808 RGD:2314366 RGD:2314604 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,673,798...31,677,696
JBrowse link
G CCNE1 cyclin E1 ISO protein:increased expression:kidney RGD PMID:17825795 RGD:2289273 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,366
JBrowse link
G CCR2 C-C motif chemokine receptor 2 no_association ISO associated with Diabetes Mellitus, Insulin-Dependent
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.V64I (human)
RGD PMID:11756347 PMID:17631861 RGD:2313558 RGD:2313563 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CCR5 chemokine (C-C motif) receptor 5 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :59029G>A (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:59029G>A (human)
RGD PMID:12610055 PMID:17428349 RGD:2307107 RGD:8549756 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,902
JBrowse link
G CD36 CD36 molecule ISO protein:increased expression:renal proximal tubule, endothelial cell RGD PMID:15737001 RGD:2307215 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G CD38 CD38 molecule ISO associated with Diabetes Mellitus, Experimental RGD PMID:19073639 PMID:19300526 RGD:2307227 RGD:2307228 NCBI chr 8:11,083,682...11,130,783
Ensembl chr 8:11,083,682...11,130,785
JBrowse link
G CD40LG CD40 ligand ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:serum RGD PMID:18756582 RGD:2314208 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27652271 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO mRNA, protein:increased expression:kidney, glomerulus RGD PMID:15698433 PMID:16805985 RGD:2293619 RGD:2293628 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
JBrowse link
G CFL1 cofilin 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:renal glomerulus (rat) RGD PMID:24726496 RGD:11570419 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CLU clusterin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:18949565 RGD:9068414 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,590...11,352,475
JBrowse link
G CNDP1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17942768 PMID:21393041 PMID:21573905 RGD:7207213 NCBI chr 1:149,523,983...149,564,728
Ensembl chr 1:149,521,510...149,562,528
JBrowse link
G CNDP2 carnosine dipeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21573905 NCBI chr 1:149,565,327...149,584,319
Ensembl chr 1:149,565,339...149,584,292
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus (rat) RGD PMID:22903132 RGD:8552684 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,003
JBrowse link
G COL4A1 collagen type IV alpha 1 chain ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17582205 PMID:18682491 PMID:19466391 PMID:27997345 RGD:2311340 RGD:2311342 NCBI chr11:76,858,332...76,997,409 JBrowse link
G CPB2 carboxypeptidase B2 susceptibility ISO protein:increased expression:plasma
DNA:SNP:cds:1040C>T(human)
RGD PMID:12574207 PMID:22932273 RGD:7243116 RGD:7243123 NCBI chr11:21,234,447...21,298,250
Ensembl chr11:21,234,447...21,298,244
JBrowse link
G CREB1 cAMP responsive element binding protein 1 susceptibility ISO RGD PMID:15862029 RGD:10059365 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,697,408...110,771,755
JBrowse link
G CRP C-reactive protein, pentraxin-related disease_progression ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
RGD PMID:22590912 PMID:22885250 RGD:6906965 RGD:6906967 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G CSF1R colony stimulating factor 1 receptor disease_progression ISO associated with Diabetes Mellitus, Type 2 RGD PMID:19466391 RGD:2311340 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,138...151,147,634
JBrowse link
G CST3 cystatin C ISO protein:increased expression:serum (human)
protein:increased expression:plasma (rat)
RGD PMID:18946178 PMID:19132849 RGD:2314297 RGD:2314328 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:plasma: RGD PMID:18026823 RGD:2312302 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G CUBN cubilin ISO RGD PMID:17037740 RGD:1599655 NCBI chr10:43,102,931...43,414,692
Ensembl chr10:43,102,946...43,414,613
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:17425653 PMID:19073786 RGD:2311357 RGD:2311359 NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22791342 RGD:7257674 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYBA cytochrome b-245 alpha chain ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :242C>T (human) RGD PMID:14747204 RGD:8695982 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,154...1,021,418
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-344C>T (human) RGD PMID:16672053 RGD:2307295 NCBI chr 4:1,365,725...1,373,138 JBrowse link
G CYP19A2 cytochrome P450 19A2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22301628 RGD:7257708 NCBI chr 1:120,652,172...120,695,899
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G DCN decorin ISO protein:increased expression:plasma, urine
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;mRNA, protein:decreased expression:kidney cortex, glomerulus
RGD PMID:11259366 PMID:12187087 PMID:16868749 PMID:17884968 RGD:2311411 RGD:2311412 RGD:2311415 RGD:2311416 NCBI chr 5:91,678,601...91,713,925
Ensembl chr 5:91,678,608...91,714,235
JBrowse link
G DGKH diacylglycerol kinase eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr11:24,772,396...24,970,928
Ensembl chr11:24,784,407...24,971,045
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20019166 RGD:6907383 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,450
JBrowse link
G EDN1 endothelin 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased secretion:plasma (human) RGD PMID:18346810 RGD:2313284 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
G EDNRA endothelin receptor type A ISO associated with Diabetes Mellitus, Experimental RGD PMID:21191784 RGD:4892326 NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853
JBrowse link
G EGF epidermal growth factor ISO RGD PMID:17475821 RGD:6906912 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,365...112,330,046
JBrowse link
G ELMO1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17942768 NCBI chr18:36,755,026...37,336,095 JBrowse link
G ENG endoglin ISO associated with Diabetes Mellitus, Insulin-Dependent; mRNA:increased expression:kidney RGD PMID:19395281 RGD:2313795 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,306,120...268,343,827
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:19506043 RGD:6906926 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
JBrowse link
G EP300 E1A binding protein p300 treatment ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat) RGD PMID:19268536 RGD:2311716 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,815...94,254,079
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21832210 RGD:5688728 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,977...11,293,412
JBrowse link
G EPO erythropoietin ISO associated with Diabetes Mellitus, Experimental;
Protein:decreased expression:serum
DNA:snp:promoter:-1125T>G(rs1617640)(human)
RGD PMID:18458324 PMID:19356735 PMID:19619913 RGD:2313832 RGD:2313833 RGD:2313838 NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney: RGD PMID:10749885 RGD:9685546 NCBI chr 6:68,667,651...68,682,629
Ensembl chr 6:68,669,153...68,682,624
JBrowse link
G ESR1 estrogen receptor 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:snps:introns: multiple(human)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:glomerulus
RGD PMID:15550505 PMID:16464734 PMID:18305958 RGD:2314005 RGD:2314020 RGD:2314023 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G F2 coagulation factor II, thrombin disease_progression ISO DNA:polymorphism: :20210G>A(human)
protein:increased expression:plasma (human)
RGD PMID:14983223 PMID:21574459 PMID:21955218 RGD:2313643 RGD:6893574 RGD:6893575 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:15004866 RGD:2313863 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,992...122,837,672
JBrowse link
G FABP2 fatty acid binding protein 2 ISO DNA:polymorphism:CDS:amino acid A54T, in a Brazilian population RGD PMID:16249461 RGD:1578457 NCBI chr 8:104,464,342...104,468,059
Ensembl chr 8:104,464,342...104,470,480
JBrowse link
G FAS Fas cell surface death receptor ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:renal distal tubule (rat)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney
mRNA:increased expression:kidney
RGD PMID:12861046 PMID:17851466 PMID:18287563 RGD:2312739 RGD:2315705 RGD:8686421 NCBI chr14:100,927,305...100,954,781 JBrowse link
G FASLG Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney RGD PMID:17851466 RGD:2315705 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,475
JBrowse link
G FBN1 fibrillin 1 onset ISO associated with Diabetes Mellitus, Experimental RGD PMID:16380460 PMID:16395273 RGD:7365077 RGD:7365080 NCBI chr 1:123,102,011...123,359,649
Ensembl chr 1:123,102,009...123,359,649
JBrowse link
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:kidney RGD PMID:19279131 RGD:2315842 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,878...101,343,916
JBrowse link
G FGF21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:25625802 RGD:10401920 NCBI chr 6:54,082,653...54,084,532
Ensembl chr 6:54,080,739...54,084,604
JBrowse link
G FGF23 fibroblast growth factor 23 severity ISO mRNA,protein:increased expression:kidney: RGD PMID:23967103 RGD:10044235 NCBI chr 5:66,028,591...66,038,078
Ensembl chr 5:66,028,776...66,037,739
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine RGD PMID:15610240 RGD:2313731 NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,620,700...5,795,264
JBrowse link
G FMOD fibromodulin ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA:decreased expression:kidney cortex
mRNA,protein:increased expression:Kidney Glomerulus
RGD PMID:11259366 PMID:16868749 RGD:2311412 RGD:2311416 NCBI chr 9:64,062,995...64,073,853
Ensembl chr 9:64,062,999...64,073,859
JBrowse link
G FN1 fibronectin 1 treatment ISO protein:increased expression:kidney cortex:
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16301823 PMID:22736507 PMID:24413998 RGD:10402169 RGD:7206843 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G FUCA1 alpha-L-fucosidase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased activity;urine RGD PMID:8343614 RGD:2315943 NCBI chr 6:81,638,213...81,655,993
Ensembl chr 6:81,637,989...81,723,231
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO associated with Hypertension RGD PMID:21987533 RGD:10449128 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G GAS6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 NCBI chr11:78,848,797...78,880,733
Ensembl chr11:78,848,794...78,881,272
JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO RGD PMID:9519709 RGD:2313353 NCBI chr 3:73,028,750...73,086,191
Ensembl chr 3:72,983,188...73,085,319
JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP:3' utr RGD PMID:14764791 RGD:2307362 NCBI chr 2:78,285,208...78,328,288
Ensembl chr 2:78,285,203...78,329,002
JBrowse link
G GHR growth hormone receptor susceptibility ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney RGD PMID:10541297 PMID:10614635 PMID:10990443 PMID:15066219 RGD:2307364 RGD:2307368 RGD:2307369 RGD:2307370 NCBI chr16:27,126,300...27,422,618
Ensembl chr16:27,126,286...27,422,268
JBrowse link
G GIPR gastric inhibitory polypeptide receptor ISO RGD PMID:19211686 RGD:2306734 NCBI chr 6:52,022,667...52,033,959
Ensembl chr 6:52,022,681...52,033,954
JBrowse link
G GLO1 glyoxalase I ISO DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003 RGD:7242569 NCBI chr 7:34,156,194...34,183,560
Ensembl chr 7:34,068,806...34,183,528
JBrowse link
G GPX1 glutathione peroxidase 1 ISO associated with Diabetes Mellitus, Type 1
protein:increased expression:glomerulus
RGD PMID:16249459 PMID:17609286 RGD:11068479 RGD:2306609 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G GPX3 glutathione peroxidase 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:serum (human) RGD PMID:17269729 RGD:2312635 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,436...5,227,748
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr14:43,305,255...43,445,626
Ensembl chr14:43,224,930...43,442,985
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO protein:decreased expression:cortex of kidney (rat) RGD PMID:23196710 RGD:13792785 NCBI chr 8:1,737,960...1,792,390
Ensembl chr 8:1,738,135...1,792,861
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr 2:80,496,105...80,527,208
Ensembl chr 2:80,507,009...80,527,210
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:26888388 RGD:13792773 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574
JBrowse link
G GSR glutathione-disulfide reductase treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;protein:decreased activity:kidney
RGD PMID:23626958 PMID:24947049 RGD:10401899 RGD:7257582 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO associated with Diabetes mellitus, Type 1;
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
protein:increased expression:plasma
RGD PMID:20980978 PMID:22015481 PMID:22997966 RGD:7245497 RGD:7245960 RGD:7246890 NCBI chr16:66,162,318...66,208,868 JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585
JBrowse link
G HDAC4 histone deacetylase 4 treatment ISO protein:increased expression:kidney:
mRNA,protein:increased expression:kidney:
RGD PMID:24717296 RGD:9590311 NCBI chr15:138,378,237...138,657,266
Ensembl chr15:138,381,627...138,614,301
JBrowse link
G HDAC5 histone deacetylase 5 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chr12:19,077,910...19,119,463
Ensembl chr12:19,077,997...19,123,140
JBrowse link
G HFE homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,768,741
JBrowse link
G HGF hepatocyte growth factor ISO RGD PMID:16340242 RGD:2313567 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,437,087...98,513,156
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21849637 RGD:10755581
G HNF4A hepatocyte nuclear factor 4 alpha ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:17330940 RGD:7242762 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO protein:increased expression:glomerulus, podocyte:
mRNA,protein:increased expression:glomerulus:
RGD PMID:21931298 RGD:10402764 NCBI chr 3:10,038,074...10,039,441
Ensembl chr 3:10,037,936...10,039,915
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO associated with Diabetes Mellitus Type 2;
associated with Diabetes Mellitus, Experimental;
RGD PMID:12213354 PMID:18175064 RGD:7257686 RGD:7257687 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,961...20,619,629
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.K469E (rs5498) (human)
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney (mouse)
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
RGD PMID:18299691 PMID:18505543 PMID:19246972 PMID:20447389 RGD:2312766 RGD:2313470 RGD:2313475 RGD:4145414 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IFNG interferon gamma ISO mRNA, protein:increased expression:kidney, T cell RGD PMID:22286547 RGD:6893364 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IGF1 insulin like growth factor 1 ISO associated with Diabetes Mellitus, Experimental;protein:decreased expression:serum (rat) RGD PMID:10444029 PMID:17194636 RGD:12904967 RGD:2313764 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA,protein:increased expression:kidney: RGD PMID:19008912 RGD:10046022 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,925...137,690,666
JBrowse link
G IGF2 insulin like growth factor 2 ISO associates with Diabetes Mellitus; mRNA:decreased expression:brain:
associated with Diabetes Mellitus, Type 2; mRNA:decreased expression:neural tissue, liver:
RGD PMID:8764603 PMID:9336345 RGD:5510019 RGD:5510022 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr18:50,018,487...50,022,799
Ensembl chr18:50,018,487...50,022,799
JBrowse link
G IL10 interleukin 10 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 RGD:2308943 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
no_association
ISO associated with Diabetes Mellitus, Type 2; DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:16174285 PMID:17286233 RGD:6907371 RGD:6909120
G IL6 interleukin 6 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney (rat)
associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
RGD PMID:18716362 PMID:19052104 PMID:19542902 RGD:2307281 RGD:2307282 RGD:7829816 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G INS insulin resistance ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:2143390 PMID:7713310 PMID:7987072 PMID:22068113 RGD:6902908 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G IRS2 insulin receptor substrate 2 ISO mRNA:increased expression:kidney tubule: RGD PMID:23617393 RGD:7257702 NCBI chr11:76,626,158...76,654,639
Ensembl chr11:76,626,179...76,653,881
JBrowse link
G ITGA2 integrin subunit alpha 2 severity ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:mesangial cell (human) RGD PMID:8989742 RGD:2307420 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G KDM6A lysine demethylase 6A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,759...40,154,194
JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18630688 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:21439372 RGD:6893386 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,297,835
JBrowse link
G KL klotho treatment ISO protein:decreased expression:kidney: RGD PMID:24136780 RGD:10403079 NCBI chr11:9,427,236...9,479,251
Ensembl chr11:9,427,198...9,478,346
JBrowse link
G KLK1 kallikrein 1 ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:17272402 PMID:19516248 RGD:1641794 NCBI chr 6:55,570,632...55,576,398
Ensembl chr 6:55,570,630...55,576,637
JBrowse link
G KLKB1 kallikrein B1 disease_progression ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,624
JBrowse link
G KNG1 kininogen 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :7965C>T (human) RGD PMID:17065357 RGD:2311541 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,277...124,557,376
JBrowse link
G LAMB2 laminin subunit beta 2 ISO RGD PMID:19864299 RGD:7207449 NCBI chr13:31,738,282...31,750,623
Ensembl chr13:31,738,284...31,771,220
JBrowse link
G LCN2 lipocalin 2 ISO protein:increased expression:urine
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
RGD PMID:22015481 PMID:22997966 RGD:7245497 RGD:7245960 NCBI chr 1:268,609,975...268,614,651 JBrowse link
G LEP leptin ISO RGD PMID:22773754 RGD:6907074 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,447
JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28130181 PMID:29988851 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,798,979...146,896,108
JBrowse link
G LMNA lamin A/C ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:cds:1908C>T (human) RGD PMID:16117820 RGD:2306095 NCBI chr 4:93,899,019...93,927,255
Ensembl chr 4:93,899,026...93,949,398
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:1789335 RGD:2311543 NCBI chr 2:103,568,366...103,659,589
Ensembl chr 2:103,567,601...103,661,079
JBrowse link
G LOC110256000 membrane primary amine oxidase-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:14977883 NCBI chr12:19,996,324...20,007,006 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:19769609 PMID:22086159 RGD:7175266 RGD:7175519
G LOC110261221 cytochrome P450 2J2-like ISO associated with Diabetes Mellitus, Experimental; RGD PMID:21742052 RGD:7243153 NCBI chr 6:152,321,816...152,358,179
Ensembl chr 6:152,321,848...152,648,979
JBrowse link
G LPL lipoprotein lipase susceptibility ISO RGD PMID:16813599 RGD:2306755 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814
JBrowse link
G LTA lymphotoxin alpha ISO DNA:polymorphism RGD PMID:18575614 RGD:2313255 NCBI chr 7:23,696,387...23,698,280
Ensembl chr 7:23,696,039...23,698,302
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:19923143 RGD:7243957 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activity:kidney RGD PMID:19066844 RGD:2311566 NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,104...31,862,038
JBrowse link
G MDK midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:17607302 NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,782...16,133,510
JBrowse link
G MFN2 mitofusin 2 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:26123583 PMID:27997345 RGD:11053290 RGD:12910740 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439
JBrowse link
G MIR145 microRNA mir-145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24223694 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211
JBrowse link
G MIR21 microRNA mir-21 ISO RNA:increased expression:kidney RGD PMID:30847937 RGD:41410820 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MLLT3 MLLT3 super elongation complex subunit treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23077601 RGD:9686143 NCBI chr 1:202,317,458...202,604,308
Ensembl chr 1:202,317,453...202,607,061
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO RGD PMID:21277817 RGD:7241216 NCBI chr 9:33,473,625...33,483,630
Ensembl chr 9:33,473,085...33,483,679
JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23384615 RGD:13204971 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,594...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO associated with Diabetes Mellitus, Type 2;DNA:repeat:promoter
associated with Diabetes Mellitus, Experimental
RGD PMID:11576356 PMID:23384615 RGD:13204971 RGD:8547866 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association
susceptibility
ISO associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:14737040 PMID:18280442 RGD:6893524 RGD:6893576 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MTOR mechanistic target of rapamycin kinase susceptibility ISO associated with Diabetes Mellitus, Experimental
DNA:SNP,haplotype: :rs7212142(human)
RGD PMID:21606597 PMID:23827786 PMID:28536139 RGD:10003168 RGD:13506787 RGD:7245564 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO Associated with Diabetes Mellitus, Type 1;DNA:SNP:cds:66A>G, (rs1801394) (human) RGD PMID:18774994 RGD:6893652 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,224...74,270,802
JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney,glomerulus
RGD PMID:22591908 PMID:22903132 RGD:13792578 RGD:8552684 NCBI chr 2:15,031,147...15,036,880
Ensembl chr 2:15,031,149...15,036,880
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental
RGD
CTD
PMID:20103708 PMID:21439372 PMID:23064900 RGD:10412718 RGD:6893386 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G NOS1 nitric oxide synthase 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:10966937 PMID:23548923 RGD:13824991 RGD:7257655 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,972
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
treatment
no_association
ISO associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
RGD
CTD
PMID:10741691 PMID:10868974 PMID:20042665 PMID:29336891 RGD:13504726 RGD:7421530 RGD:7421534 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G NOX4 NADPH oxidase 4 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney cortex
RGD PMID:16135519 PMID:17511984 RGD:2324670 RGD:2324673 NCBI chr 9:22,622,105...22,776,691
Ensembl chr 9:22,624,195...22,776,554
JBrowse link
G NPPA natriuretic peptide A no_association
disease_progression
ISO DNA:polymorphism:intron
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:blood
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :2238T>C (human)
RGD PMID:9681733 PMID:10381153 PMID:10404802 PMID:15111511 RGD:2313590 RGD:2313592 RGD:2313593 RGD:7247731 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G NPPB natriuretic peptide B ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:10404802 PMID:16917760 RGD:7247731 RGD:7248603 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21457706 RGD:11035226 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,769...17,302,590
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:20557422 RGD:4891134 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,379...30,429,882
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20621183 RGD:11073737 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,159...14,241,197
JBrowse link
G PAX2 paired box 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney cortex RGD PMID:15149326 RGD:2316747 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,834,168...111,914,304
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:increased expression:kidney RGD PMID:12808179 RGD:2311649 NCBI chr 3:296,399...322,967
Ensembl chr 3:303,311...323,036
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 Ensembl chr 5:8,986,461...9,007,446 JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,754...151,192,647
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:glomerulus RGD PMID:15042541 RGD:2311655 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,582,481...14,723,336
JBrowse link
G PGF placental growth factor disease_progression ISO associated with Diabetes Mellitus, Type 1 RGD PMID:21988672 RGD:6483606 NCBI chr 7:98,149,510...98,162,784 JBrowse link
G PLAT plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16598198 RGD:2311671 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032
JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:renal glomerulus (rat) RGD PMID:15322501 RGD:1580123 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172
JBrowse link
G PON1 paraoxonase 1 susceptibility
no_association
ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent
associated with Diabetes Mellitus;DNA:missense mutations:cds:p.L55M, p.Q192R (rs854560, rs662) (human)
CTD
RGD
PMID:15270786 PMID:19207863 PMID:24100645 PMID:26884296 RGD:2313266 RGD:8547548 RGD:8547572 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PON2 paraoxonase 2 ISO associated with type 1 diabetes mellitus;DNA:missense mutation:cds:p.C311S (human)
associated with type 2 diabetes mellitus;DNA:polymorphisms:multiple
RGD PMID:11206400 PMID:11918623 RGD:1580218 RGD:2313492 NCBI chr 9:75,027,270...75,051,441
Ensembl chr 9:75,027,097...75,051,422
JBrowse link
G POSTN periostin ISO mRNA,protein:increased expression:kidney: RGD PMID:22167593 RGD:10040972 NCBI chr11:13,225,183...13,258,973
Ensembl chr11:13,182,272...13,259,019
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD
CTD
PMID:18388116 PMID:18780770 PMID:28182703 RGD:2301845 RGD:2301862 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO DNA:polymorphism:exon:p.G482S (human)
mRNA:decreased expression:kidney (human)
RGD PMID:19900151 PMID:21784897 RGD:7242027 RGD:7242045 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,961,909
JBrowse link
G PRKCB protein kinase C beta ISO associated with hypertension;protein:increased expression:glomerular mesangium RGD PMID:12540629 RGD:729635 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264
JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020
JBrowse link
G PRMT1 protein arginine methyltransferase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23159951 RGD:9491822 NCBI chr 6:54,718,845...54,730,411
Ensembl chr 6:54,711,393...54,732,574
JBrowse link
G PROS1 protein S treatment
severity
ISO associated with diabetes mellitus, experimental;mRNA, protein:increased expression:kidney, glomerulus RGD PMID:29511111 RGD:13515131 NCBI chr13:165,915,298...165,999,118
Ensembl chr13:165,911,366...165,999,811
JBrowse link
G PRSS2 serine protease 2 ISO protein:increased expression:urine RGD PMID:18428024 RGD:2324899 NCBI chr18:7,443,327...7,446,625
Ensembl chr18:7,443,327...7,446,625
JBrowse link
G PTEN phosphatase and tensin homolog ISO protein:decreased expression:kidney cortex, glomerulus RGD PMID:16804083 RGD:2292546 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTGDS prostaglandin D2 synthase susceptibility ISO RGD PMID:15970590 RGD:1642581
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17112505 PMID:21441310 RGD:5135032 RGD:5688268 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTH parathyroid hormone ISO DNA:snps:exon, intron:g.350C>A, g.IVS2+56G>A (rs6256, rs6254) (human) RGD PMID:22777106 RGD:7242744 NCBI chr 2:45,757,398...45,760,433
Ensembl chr 2:45,757,398...45,760,415
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17900838 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G REN renin ISO RGD PMID:15489960 RGD:1579795 NCBI chr 9:64,809,143...64,822,605
Ensembl chr 9:64,809,146...64,822,636
JBrowse link
G RETN resistin ISO RGD PMID:21425555 RGD:7207159 NCBI chr 2:71,484,164...71,485,577
Ensembl chr 2:71,484,169...71,485,616
JBrowse link
G SELP selectin P severity ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney, serum
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD PMID:18026823 PMID:18471420 RGD:2312294 RGD:2312302 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,406,203
JBrowse link
G SERPINB7 serpin family B member 7 ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;DNA:SNP:intron:rs1720843 (human)
RGD PMID:16443768 PMID:19690890 RGD:7207374 RGD:7207378 NCBI chr 1:157,953,872...157,999,242
Ensembl chr 1:157,953,870...157,998,842
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus, mesangial cell (rat)
associate with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
CTD
RGD
PMID:10809802 PMID:15322501 PMID:18682491 PMID:26712211 RGD:11073694 RGD:1580123 RGD:8547711 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human protein in a mouse model
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma (human)
mRNA, protein:decreased expression:renal cortex, renal medulla (rat)
RGD PMID:15616035 PMID:18523656 PMID:23884140 RGD:1359799 RGD:8554865 RGD:8554896 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G SHAS2 hyaluronan synthase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal medulla RGD PMID:18441392 RGD:9588630 NCBI chr 4:17,583,154...17,613,524
Ensembl chr 4:17,596,472...17,675,586
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO associated with Diabetes Mellitus, Type 2;DNA:SNP:exon:g.20882C>T (human) RGD PMID:15745834 PMID:26337659 RGD:12879466 RGD:2312305 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SMAD6 SMAD family member 6 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17437042 RGD:2289036 NCBI chr 1:164,652,602...164,735,084
Ensembl chr 1:164,657,086...164,735,083
JBrowse link
G SOD1 superoxide dismutase 1 ISO human gene in a mouse model
protein:decreased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple
RGD PMID:11522679 PMID:17914031 PMID:19470681 RGD:2312361 RGD:2312365 RGD:8655571 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17192491 PMID:24819633 RGD:7175540 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,651,280...7,691,723
JBrowse link
G SOD3 superoxide dismutase 3 ISO protein:decreased expression:kidney RGD PMID:19470681 RGD:2312361 NCBI chr 8:18,796,633...18,802,156
Ensembl chr 8:18,796,636...18,802,154
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:kidney RGD PMID:8569083 RGD:2300072 NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,703...71,381,160
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:12032186 RGD:1581328 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
RGD PMID:16046298 PMID:16936198 PMID:17961514 PMID:18613221 RGD:1581418 RGD:2308806 RGD:2308811 RGD:2308815 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney RGD PMID:16046298 PMID:16936198 RGD:1581418 RGD:2308815 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,487...6,784,672
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP (human) RGD PMID:19506043 RGD:6906926 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,694...123,546,417
JBrowse link
G TF transferrin ISO RGD PMID:23468095 RGD:7244196 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,970,599
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO associated with Diabetes Mellitus, Experimental
mRNA:increased expression:glomerulus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18682491 PMID:19211686 PMID:19960420 PMID:24074026 RGD:2306734 RGD:7394855 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TGFBI transforming growth factor beta induced ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12911551 PMID:18682491 RGD:1304421 NCBI chr 2:138,191,793...138,225,373
Ensembl chr 2:138,191,804...138,225,366
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496156 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,491...16,878,165
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 ISO protein:decreased expression:glomerulus (rat) RGD PMID:15153551 RGD:1599409 NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,397...103,235,856
JBrowse link
G THBS1 thrombospondin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17878288 RGD:2317941 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,781...131,746,115
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:kidney RGD PMID:17491697 RGD:2290407 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,835
JBrowse link
G TINAG tubulointerstitial nephritis antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr 7:26,448,612...26,522,993
Ensembl chr 7:26,446,306...26,522,965
JBrowse link
G TLR2 toll like receptor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21617141 RGD:7241083 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TLR4 toll like receptor 4 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22021706 RGD:7207902 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TNF tumor necrosis factor ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
RGD PMID:12969138 PMID:16141456 PMID:16336586 PMID:21441310 RGD:1580208 RGD:1580296 RGD:1580311 RGD:5135032 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFAIP1 TNF alpha induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr12:44,616,840...44,626,330
Ensembl chr12:44,616,916...44,629,934
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b disease_progression
treatment
ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2
RGD PMID:18719882 PMID:20727867 RGD:7205493 RGD:7205514 NCBI chr 4:19,850,212...19,879,132 JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2
RGD PMID:19073786 PMID:22042131 RGD:2311357 RGD:7245547 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,073...64,331,909
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B onset ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD PMID:16408124 PMID:19073786 PMID:22266664 RGD:2311357 RGD:7245476 RGD:7245529 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,149
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO protein:increased expression:kidney RGD PMID:18287563 RGD:2312739 NCBI chr13:111,021,952...111,103,060
Ensembl chr13:110,981,604...111,107,423
JBrowse link
G TP53 tumor protein p53 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17901943 RGD:2290561 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO protein:increased expression:kidney interstitium RGD PMID:29331667 PMID:30478987 RGD:127229931 RGD:127284861 NCBI chr 7:36,510,253...36,531,796
Ensembl chr 7:36,510,253...36,531,796
JBrowse link
G TRIP10 thyroid hormone receptor interactor 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26097534 RGD:11535148 NCBI chr 2:72,406,500...72,416,146
Ensembl chr 2:72,406,175...72,416,138
JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr13:83,436,343...83,498,419
Ensembl chr13:83,436,395...83,498,422
JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 treatment
induces
ISO associated with Diabetes Mellitus, Experimental RGD PMID:22673147 PMID:29923767 RGD:149735534 RGD:7247584 NCBI chr 9:32,332,768...32,439,184
Ensembl chr 9:32,332,769...32,439,184
JBrowse link
G TXNIP thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582205 NCBI chr 4:99,348,589...99,351,760
Ensembl chr 4:99,348,575...99,352,241
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine (human) RGD PMID:17634209 RGD:2311211 NCBI chr 2:59,238,802...59,241,512 JBrowse link
G UCP1 uncoupling protein 1 no_association ISO DNA:SNP: :-3826A>G (human) RGD PMID:15120704 RGD:7247625 NCBI chr 8:86,522,028...86,526,162 JBrowse link
G UCP2 uncoupling protein 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22848482 RGD:7175295 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,333,153...8,365,558
JBrowse link
G UTS2 urotensin 2 disease_progression ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:15476950 PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 RGD:2306806 NCBI chr 6:68,552,889...68,560,827
Ensembl chr 6:68,552,887...68,559,687
JBrowse link
G UTS2R urotensin 2 receptor ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
mRNA:increased expression:kidney
RGD PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 NCBI chr12:695,765...700,678 JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO associated with Diabetes Mellitus,Type 1;protein:increased expression:plasma:
protein:increased expression:kidney
RGD PMID:20138682 PMID:23303408 RGD:7240523 RGD:7241237 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226
JBrowse link
G VDAC1 voltage dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,192...136,413,595
JBrowse link
G VDAC2 voltage dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr14:77,767,165...77,782,327
Ensembl chr14:77,766,686...77,782,322
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD
RGD
PMID:15610240 PMID:18630688 RGD:2313731 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
G VTN vitronectin ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:glomerulus RGD PMID:11728964 RGD:10003096 NCBI chr12:44,650,532...44,653,916
Ensembl chr12:44,617,499...44,660,271
JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:19458127 PMID:22302365 RGD:7247644 RGD:7247651 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,986,528...108,080,151
JBrowse link
G XYLT1 xylosyltransferase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:missense mutation:cds:p.A115S (human) RGD PMID:17003309 RGD:2313138 NCBI chr 3:27,158,438...27,492,629
Ensembl chr 3:27,158,874...27,492,892
JBrowse link
diabetic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2B adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism (human) RGD PMID:17516297 RGD:2313542 NCBI chr 3:45,760,966...45,762,306
Ensembl chr 3:45,758,268...45,764,178
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22171162 RGD:8695979 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:repeat:promoter:g.(CA)n (human)
associated with Diabetes Mellitus, Experimental
RGD PMID:9489533 PMID:16900242 RGD:1626089 RGD:8548642 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15318096 RGD:2311150 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:20587056 RGD:5129222 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410
JBrowse link
G BDNF brain derived neurotrophic factor ISO associated with Diabetes Mellitus, Experimental RGD PMID:20557422 RGD:4891134 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G BECN1 beclin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25824552 RGD:11561957 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;protein:increased expresssion:sciatic nerve
CTD
RGD
PMID:12502508 PMID:19555701 RGD:2311441 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10780678 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CAV1 caveolin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:19675140 RGD:8661787 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus;protein:increased expression:serum RGD PMID:19276232 RGD:2307060 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CD63 CD63 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:platelet RGD PMID:10547212 RGD:2314203 NCBI chr 5:21,172,275...21,176,225
Ensembl chr 5:21,171,678...21,176,232
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20624991 NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,150...12,600,249
JBrowse link
G CNR1 cannabinoid receptor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18810243 RGD:2314631 NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,466,027...56,492,602
JBrowse link
G EPO erythropoietin ISO associated with Diabetes Mellitus, Experimental; RGD PMID:19244253 RGD:2313834 NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:altered expression:plasma (human) RGD PMID:10468085 RGD:2312401 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,158...78,518,671
JBrowse link
G FGF2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:16644707 RGD:2315860 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,878...101,343,916
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO associated with Diabetes Mellitus, Experimental