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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:glucose metabolism disease
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Accession:DOID:4194 term browser browse the term
Definition:Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM.
Synonyms:exact_synonym: Glucose Metabolic Disorder;   Glucose Metabolic Disorders;   Glucose Metabolism Disorder;   Glucose Metabolism Disorders;   disorder of glucose metabolism
 primary_id: MESH:D044882;   RDO:0002537
 xref: NCI:C53655
For additional species annotation, visit the Alliance of Genome Resources.



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glucose metabolism disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNH6 potassium voltage-gated channel subfamily H member 6 ISS MouseDO NCBI chr17:63,523,334...63,548,992
Ensembl chr17:63,523,334...63,548,977
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29802709 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G RANBP2 RAN binding protein 2 ISO RGD PMID:17069463 RGD:9835347 NCBI chr 2:108,719,446...108,785,809
Ensembl chr 2:108,719,482...108,785,809
JBrowse link
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IAGP ClinVar Annotator: match by term: MITOCHONDRIAL HMG-CoA SYNTHASE DEFICIENCY
ClinVar Annotator: match by term: mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency
ClinVar
OMIM
PMID:9337379 PMID:9536098 PMID:9727719 PMID:11228257 PMID:11479731 More... NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G LOC122094910 Sharpr-MPRA regulatory region 1341 IAGP ClinVar Annotator: match by term: mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency ClinVar PMID:28492532 PMID:33045405 NCBI chr 1:119,768,486...119,768,780 JBrowse link
G PHGDH phosphoglycerate dehydrogenase IAGP ClinVar Annotator: match by term: MITOCHONDRIAL HMG-CoA SYNTHASE DEFICIENCY ClinVar NCBI chr 1:119,711,934...119,744,218
Ensembl chr 1:119,648,411...119,744,218
JBrowse link
abdominal obesity-metabolic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTF1 cardiotrophin 1 ISS MouseDO NCBI chr16:30,895,824...30,903,560
Ensembl chr16:30,896,614...30,903,547
JBrowse link
G GUCY2C guanylate cyclase 2C ISS MouseDO NCBI chr12:14,612,632...14,696,625
Ensembl chr12:14,612,632...14,696,599
JBrowse link
G LEP leptin ISS MouseDO NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G NEIL1 nei like DNA glycosylase 1 ISS MouseDO NCBI chr15:75,347,039...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:15309680 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISS MouseDO NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:23320128 RGD:7241841 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRKCI protein kinase C iota ISS MouseDO NCBI chr 3:170,222,424...170,305,981
Ensembl chr 3:170,222,424...170,305,977
JBrowse link
G SIRT3 sirtuin 3 ISS MouseDO NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931
JBrowse link
G SLC2A9 solute carrier family 2 member 9 ISS MouseDO NCBI chr 4:9,771,125...10,040,270
Ensembl chr 4:9,771,153...10,054,936
JBrowse link
abdominal obesity-metabolic syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:increased oxidation:cardiac muscle cell RGD PMID:23997093 RGD:13782087 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G FADD Fas associated via death domain treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:30172001 RGD:13792561 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G LEP leptin ISS OMIM:605552 MouseDO NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LPL lipoprotein lipase treatment ISO RGD PMID:26996629 RGD:13794382 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MTTP microsomal triglyceride transfer protein IAGP ClinVar Annotator: match by term: Metabolic syndrome, protection against OMIM
ClinVar
PMID:16721486 PMID:28492532 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO RGD PMID:19841034 RGD:15090861 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 ISS OMIM:605552 MouseDO NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378
JBrowse link
abdominal obesity-metabolic syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHDC1 AT-hook DNA binding motif containing 1 IAGP ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 ClinVar PMID:25741868 PMID:29696776 PMID:33644933 NCBI chr 1:27,534,245...27,604,178
Ensembl chr 1:27,534,035...27,604,431
JBrowse link
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B IAGP ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 ClinVar
OMIM
PMID:24827035 PMID:25741868 NCBI chr19:39,825,350...39,834,162
Ensembl chr19:39,825,350...39,834,201
JBrowse link
abdominal obesity-metabolic syndrome 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELA2A chymotrypsin like elastase 2A IAGP OMIM NCBI chr 1:15,456,732...15,472,091
Ensembl chr 1:15,456,728...15,472,091
JBrowse link
adrenocorticotropic hormone deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE65 retinoid isomerohydrolase RPE65 IAGP ClinVar Annotator: match by term: Adrenocorticotropic hormone deficiency ClinVar PMID:9326941 PMID:9501220 PMID:9843205 PMID:18632300 PMID:25741868 More... NCBI chr 1:68,428,822...68,450,322
Ensembl chr 1:68,428,822...68,449,954
JBrowse link
G TBX19 T-box transcription factor 19 IAGP
EXP
ClinVar Annotator: match by term: ACTH DEFICIENCY, ISOLATED
ClinVar Annotator: match by term: Adrenocorticotropic hormone deficiency
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:2830787 PMID:11290323 PMID:12651888 PMID:15476446 PMID:16390921 More... NCBI chr 1:168,280,877...168,314,426
Ensembl chr 1:168,280,877...168,314,426
JBrowse link
autosomal dominant Wolfram syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WFS1 wolframin ER transmembrane glycoprotein IAGP ClinVar Annotator: match by term: Wolfram-like syndrome, autosomal dominant
ClinVar Annotator: match by term: HEARING LOSS, PROGRESSIVE, WITH OPTIC ATROPHY AND/OR IMPAIRED GLUCOSE REGULATION
ClinVar
OMIM
PMID:10679252 PMID:11295831 PMID:15605410 PMID:16648378 PMID:17492394 More... NCBI chr 4:6,260,368...6,303,265
Ensembl chr 4:6,269,849...6,303,265
JBrowse link
background diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin treatment IDA RGD PMID:10848441 RGD:10046010 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G CAT catalase IEP associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IEP protein:decreased expression:aqueous humor: RGD PMID:23853629 RGD:10402120 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G PDGFB platelet derived growth factor subunit B IEP protein:decreased expression:vitreous: RGD PMID:19799585 RGD:10449447 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
carnitine palmitoyltransferase I deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPT1A carnitine palmitoyltransferase 1A IAGP ClinVar Annotator: match by term: Carnitine palmitoyltransferase I deficiency
ClinVar Annotator: match by term: Carnitine Palmitoyltransferase IA Deficiency
ClinVar Annotator: match by term: Carnitine palmitoyl transferase 1 deficiency
ClinVar Annotator: match by term: Carnitine palmitoyltransferase type I deficiency
ClinVar Annotator: match by term: CPT deficiency, hepatic, type IA
ClinVar Annotator: match by term: Carnitine palmitoyl transferase 1A deficiency
ClinVar
OMIM
PMID:9048718 PMID:9536098 PMID:9691089 PMID:11350182 PMID:11350183 More... NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
Carnitine Palmitoyltransferase II Deficiency, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPT2 carnitine palmitoyltransferase 2 IAGP ClinVar Annotator: match by term: Carnitine palmitoyltransferase II deficiency, infantile ClinVar
OMIM
PMID:736528 PMID:835844 PMID:1086878 PMID:1528846 PMID:1999498 More... NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
JBrowse link
cataract 47 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC16A12 solute carrier family 16 member 12 IAGP ClinVar Annotator: match by term: CATARACT, JUVENILE, WITH MICROCORNEA
ClinVar Annotator: match by term: Cataract, juvenile, with microcornea and glucosuria
ClinVar
OMIM
PMID:17458810 PMID:18304496 PMID:21778275 PMID:25741868 PMID:26376857 NCBI chr10:89,430,299...89,536,029
Ensembl chr10:89,430,299...89,556,641
JBrowse link
Childhood-Onset Spasticity with Hyperglycinemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 IAGP ClinVar Annotator: match by term: Spasticity, childhood-onset, with hyperglycinemia ClinVar
OMIM
PMID:24334290 NCBI chr14:95,535,050...95,544,714
Ensembl chr14:95,533,503...95,544,724
JBrowse link
chromosome 17q11.2 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF135 ring finger protein 135 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: VAN ASPEREN SYNDROME
ClinVar Annotator: match by term: Macrocephaly, macrosomia, facial dysmorphism syndrome
CTD
ClinVar
PMID:17632510 PMID:21681106 PMID:25741868 PMID:27535533 PMID:28135719 More... NCBI chr17:30,968,642...30,999,911
Ensembl chr17:30,970,984...30,999,911
JBrowse link
Cleft Palate, Proliferative Retinopathy, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRC32 leucine rich repeat containing 32 IAGP ClinVar Annotator: match by term: CLEFT PALATE, PROLIFERATIVE RETINOPATHY, AND DEVELOPMENTAL DELAY
ClinVar Annotator: match by term: Cleft palate, proliferative retinopathy, and developmental delay
ClinVar
OMIM
PMID:30976112 NCBI chr11:76,657,524...76,670,747
Ensembl chr11:76,657,524...76,670,747
JBrowse link
Combined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 IAGP ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus ClinVar
OMIM
PMID:25466870 PMID:25741868 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 IAGP ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus ClinVar PMID:2256350 PMID:22563501 PMID:24220513 PMID:32214227 PMID:33983693 NCBI chr 1:65,264,749...65,415,871
Ensembl chr 1:65,248,219...65,415,871
JBrowse link
Congenital Hyperinsulinism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 IAGP
EXP
ClinVar Annotator: match by term: Familial hyperinsulinism
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: familial hyperinsulinism
ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy
DNA:mutations:exon:multiple
DNA:missense mutations, nonsense mutations, splice-site mutations:CDS:multiple
DNA:missense mutations:exon:p.G1485E (c.4454G>A), p.D1506E (c.4518C>A), p.M1544K (c.4541T>A) (human)
DNA:mutations:exon, intron:multiple
DNA:deletion: :p.S1387del (human)
ClinVar
CTD
RGD
PMID:7716548 PMID:8751851 PMID:8923011 PMID:9041101 PMID:9536098 More... RGD:704365, RGD:12790723, RGD:11069847, RGD:12790596, RGD:11067821, RGD:12790587, RGD:11070657, RGD:12743628 NCBI chr11:17,392,498...17,476,849
Ensembl chr11:17,392,498...17,476,894
JBrowse link
G GCK glucokinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15277402 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GLUD1 glutamate dehydrogenase 1 IAGP DNA:missense mutations: : RGD PMID:9571255 RGD:1302513 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase IAGP DNA:deletion:cds (human) RGD PMID:14693719 RGD:2306664 NCBI chr 4:107,989,839...108,035,171
Ensembl chr 4:107,989,714...108,035,241
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha IAGP DNA:mutations: :
ClinVar Annotator: match by term: Familial hyperinsulinism
ClinVar
RGD
PMID:10227563 PMID:10447526 PMID:10768098 PMID:10983627 PMID:15281001 More... RGD:12904701 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,432,845
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 IAGP
EXP
DNA:missense mutation:exon:p.R34H (c.101G>A) (human)
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exon:c.151G>T, c.1017G>T (human)
DNA:missense mutations, frameshift mutations:CDS:multiple
DNA:deletion, frameshift mutation, missense mutations:exon:multiple
DNA:deletion, insertion:exon
ClinVar
CTD
RGD
PMID:9867219 PMID:11872696 PMID:12196481 PMID:12475776 PMID:15579781 More... RGD:12743624, RGD:12790723, RGD:11069847, RGD:12790587, RGD:12743643 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
G KCNT2 potassium sodium-activated channel subfamily T member 2 IAGP ClinVar Annotator: match by term: KCNT2-related condition ClinVar PMID:29069600 NCBI chr 1:196,225,779...196,608,560
Ensembl chr 1:196,225,779...196,609,225
JBrowse link
G LOC110121471 VISTA enhancer hs1977 IAGP ClinVar Annotator: match by term: Familial hyperinsulinism ClinVar PMID:8751851 PMID:9618169 PMID:10194514 PMID:10334322 PMID:10338089 More... NCBI chr11:17,412,970...17,415,128 JBrowse link
G TBC1D4 TBC1 domain family member 4 IAGP RGD PMID:19470471 RGD:7248544 NCBI chr13:75,283,503...75,483,144
Ensembl chr13:75,283,503...75,482,169
JBrowse link
G UCP2 uncoupling protein 2 IAGP ClinVar Annotator: match by term: Familial hyperinsulinism ClinVar PMID:25741868 NCBI chr11:73,974,671...73,983,202
Ensembl chr11:73,974,672...73,982,843
JBrowse link
Developmental Delay, Epilepsy, and Neonatal Diabetes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 IAGP ClinVar Annotator: match by term: DEND syndrome ClinVar PMID:25741868 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
Diabetes Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B EXP CTD Direct Evidence: marker/mechanism CTD PMID:25304492 PMID:25541468 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member EXP CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:20479236 RGD:7241550 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:20479236 RGD:7241550 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24252320 RGD:13782355 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 IAGP RGD PMID:15963101 RGD:2307154 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IAGP Associated with obesity RGD PMID:21282363 RGD:6906933 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G GHRL ghrelin and obestatin prepropeptide IEP protein: decreased expression: serum RGD PMID:18025762 RGD:7242563 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GLO1 glyoxalase I no_association IAGP DNA:SNP: :419C>A (human) RGD PMID:21738003 RGD:7242569 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HP haptoglobin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19769483 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G MIR140 microRNA 140 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32062618 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180
JBrowse link
G MUC1 mucin 1, cell surface associated ISO associated with Diabetes Mellitus, Experimental RGD PMID:23977093 RGD:7349380 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 1:26,911,489...26,914,110
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:diaphragm RGD PMID:23443767 RGD:7327179 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PON1 paraoxonase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19003935 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21548839 RGD:6484542 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
JBrowse link
G SLC10A2 solute carrier family 10 member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr13:103,043,998...103,066,417
Ensembl chr13:103,043,998...103,066,417
JBrowse link
G SLC51A solute carrier family 51 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 3:196,216,534...196,233,427
Ensembl chr 3:196,211,487...196,243,178
JBrowse link
G SLC51B solute carrier family 51 subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr15:65,045,387...65,053,397
Ensembl chr15:65,045,387...65,053,397
JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18057998 RGD:6771339 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
diabetes mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 TAS
IAGP
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar
RGD
PMID:9618169 PMID:9648840 PMID:10204114 PMID:14692646 PMID:14715863 More... RGD:1625279 NCBI chr11:17,392,498...17,476,849
Ensembl chr11:17,392,498...17,476,894
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO protein:increased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACP1 acid phosphatase 1 IAGP RGD PMID:8620937 RGD:2313188 NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADRB1 adrenoceptor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18378355 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility IEP protein:decreased expression:plasma (human) RGD PMID:23396398 RGD:7243186 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22831748 PMID:25741868 PMID:26336158 PMID:28492532 NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO mRNA:reduced expression:pancreatic islet (mouse) RGD PMID:11904435 RGD:2313440 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G ALMS1 ALMS1 centrosome and basal body associated protein IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18154657 PMID:21157496 PMID:21943378 PMID:22876109 PMID:24033266 More... NCBI chr 2:73,385,758...73,609,919
Ensembl chr 2:73,385,758...73,625,166
JBrowse link
G ALPK1 alpha kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621
JBrowse link
G AOC3 amine oxidase copper containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr17:42,851,182...42,858,130
Ensembl chr17:42,851,184...42,858,130
JBrowse link
G APOB apolipoprotein B IEP protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOC2 apolipoprotein C2 IEP protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565
JBrowse link
G APOC3 apolipoprotein C3 IEP protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G APOE apolipoprotein E treatment IDA RGD PMID:17192461 RGD:1601230 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOH apolipoprotein H IEP protein:increased expression:plasma
mRNA:increased expression:retina
RGD PMID:9377806 PMID:18695102 RGD:2313991, RGD:2313982 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO protein:altered localization:retina RGD PMID:19748503 RGD:2316076 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:19748503 RGD:2316076 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like ISS MouseDO NCBI chr11:13,276,552...13,387,268
Ensembl chr11:13,276,652...13,387,266
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 IEP associated with Obesity, Morbid;mRNA:decreased expression:omentum, adipose tissue (human) RGD PMID:26504501 RGD:11049459 NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422
JBrowse link
G ASIP agouti signaling protein ISO associated with Obesity;DNA:mutation (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1473152 PMID:10426381 RGD:2314006 NCBI chr20:34,186,493...34,269,344
Ensembl chr20:34,194,569...34,269,344
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:19667185 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 8:11,493,991...11,564,599
Ensembl chr 8:11,486,894...11,564,599
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:23430896 PMID:23963299 PMID:25588603 PMID:25741868 PMID:26467025 More... NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845
JBrowse link
G CASP3 caspase 3 ISO protein:increased expression:ovary RGD PMID:28412870 RGD:40400904 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11117918 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CAVIN1 caveolae associated protein 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr17:42,402,449...42,423,269
Ensembl chr17:42,402,449...42,423,256
JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased expression:serum RGD PMID:18385799 RGD:2307062 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD36 CD36 molecule ISO protein:increased expression:macrophage RGD PMID:17551591 RGD:2307209 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD40LG CD40 ligand IEP associated with Coronary Arteriosclerosis, Myocardial Infarction; protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 IAGP DNA:snp: :rs10946398(human) RGD PMID:19741467 RGD:2313940 NCBI chr 6:20,534,457...21,232,404
Ensembl chr 6:20,534,457...21,232,404
JBrowse link
G CEL carboxyl ester lipase IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861
JBrowse link
G CLOCK clock circadian regulator ISS MouseDO NCBI chr 4:55,427,903...55,547,138
Ensembl chr 4:55,427,903...55,546,909
JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12572680 NCBI chr 3:149,162,410...149,222,008
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPB2 carboxypeptidase B2 IEP protein:increased expression, increased activity:plasma RGD PMID:14983223 RGD:2313643 NCBI chr13:46,053,066...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19233164 NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CSF1R colony stimulating factor 1 receptor IDA associated with hepatocellular��carcinoma;DNA:hypermethylation:promoter (human) RGD PMID:32724427 RGD:150524282 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CTSB cathepsin B onset IAGP DNA:transversion:cds:p.L26V (human) RGD PMID:18706099 RGD:2315528 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23307960 RGD:9491759 NCBI chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,495...39,281,735
JBrowse link
G CYB5R4 cytochrome b5 reductase 4 ISO RGD PMID:15247412 RGD:2315644 NCBI chr 6:83,859,689...83,967,423
Ensembl chr 6:83,859,656...83,967,423
JBrowse link
G CYBB cytochrome b-245 beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,059...37,813,461
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 IAGP DNA:polymorphisms:5' utr, cds:-344C>T, p.K173R (human) RGD PMID:11687612 RGD:2307297 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP associated with Smoking Inhalation Injury; DNA:polymorphism:3' UTR:5639T>C (human) RGD PMID:11996959 RGD:2307073 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 IAGP DNA:polymorphism:multiple (human)
associated with Thromboembolism; DNA:polymorphism:cds:R144C, I359L (human)
RGD PMID:16788382 PMID:16303885 RGD:2307151, RGD:2307153 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO mRNA,protein:decreased expression:liver RGD PMID:10876162 RGD:41412168 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
JBrowse link
G DICER1 dicer 1, ribonuclease III ISO RGD PMID:22216196 RGD:149735536 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:decreased expression:urine
protein:increased expression:plasma
RGD PMID:9212353 PMID:8914465 RGD:2313869, RGD:11060253 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F7 coagulation factor VII no_association ISO
IEP
protein:increased activity:plasma (rat) RGD PMID:10899350 PMID:15258325 PMID:10910004 RGD:1598920, RGD:2312391, RGD:2312393 NCBI chr13:113,105,773...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G FN1 fibronectin 1 IEP
EXP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20551625 PMID:11213886 RGD:7206845 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOXP3 forkhead box P3 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G FUCA1 alpha-L-fucosidase 1 IEP protein:decreased activity:blood platelets RGD PMID:3609421 RGD:2315945 NCBI chr 1:23,845,077...23,868,332
Ensembl chr 1:23,845,077...23,868,290
JBrowse link
G FXN frataxin ISO DNA:deletion:exon (mouse) RGD PMID:12925693 RGD:2307048 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase IDA protein:decreased activity:blood RGD PMID:24865682 RGD:10449112 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GAD1 glutamate decarboxylase 1 ISO RGD PMID:1924335 RGD:728511 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GATA6 GATA binding protein 6 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:20581743 PMID:22158542 PMID:23223019 PMID:24310933 More... NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G GC GC vitamin D binding protein IEP protein:increased expression:ascitic fluid RGD PMID:20054029 RGD:5509921 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GCK glucokinase IAGP neonatal-onset diabetes mellitus,OMIM:606176;DNA:point mutation:exon:T228M
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar
RGD
PMID:7542040 PMID:8325892 PMID:8433729 PMID:8446612 PMID:8454109 More... RGD:1601295 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GGT1 gamma-glutamyltransferase 1 IEP associated with Cystic Fibrosis; protein:increased activity:plasma RGD PMID:17888134 RGD:2315601 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
JBrowse link
G GH1 growth hormone 1 IEP protein:increased secretion:plasma
protein:decreased expression:vitreous body
RGD PMID:1132599 PMID:19463895 RGD:2315658, RGD:2315653 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GIPR gastric inhibitory polypeptide receptor IMP human gene, mouse model RGD PMID:15582721 RGD:2312617 NCBI chr19:45,668,187...45,683,722
Ensembl chr19:45,668,221...45,683,722
JBrowse link
G GLIS3 GLIS family zinc finger 3 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 9:3,824,127...4,310,694
Ensembl chr 9:3,824,127...4,348,392
JBrowse link
G GLIS3-AS1 GLIS3 antisense RNA 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:3,898,646...3,901,248
Ensembl chr 9:3,898,642...3,901,248
JBrowse link
G GLUD1 glutamate dehydrogenase 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G GNB3 G protein subunit beta 3 no_association IAGP DNA:polymorphism: :multiple (human) RGD PMID:16908025 RGD:2313206 NCBI chr12:6,840,922...6,847,393
Ensembl chr12:6,839,954...6,847,393
JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:skeletal muscle (mouse) RGD PMID:18936159 PMID:18562625 RGD:2312632, RGD:2312633 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GSR glutathione-disulfide reductase IEP protein:decreased activity:blood: RGD PMID:22540111 RGD:7257584 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP RGD PMID:16927413 RGD:2306632 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:16002077 RGD:5490997
G HADH hydroxyacyl-CoA dehydrogenase IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22662265 PMID:25741868 PMID:27104957 PMID:28492532 NCBI chr 4:107,989,839...108,035,171
Ensembl chr 4:107,989,714...108,035,241
JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HGF hepatocyte growth factor IEP mRNA, protein:increased expression:cornea RGD PMID:16186340 RGD:2313569 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:15476492 RGD:2313755 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HNF1A HNF1 homeobox A IAGP ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:8945470 PMID:9032114 PMID:9075818 PMID:9097962 PMID:9112026 More... NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HNF1B HNF1 homeobox B IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15930087 PMID:16249435 PMID:18065799 PMID:19639018 PMID:20633866 More... NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:10983627 PMID:16946562 PMID:18414213 PMID:24033266 PMID:25741868 More... NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,432,845
JBrowse link
G HNRNPUL2-BSCL2 HNRNPUL2-BSCL2 readthrough (NMD candidate) IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:23430896 PMID:23963299 PMID:25588603 PMID:25741868 PMID:26467025 More... NCBI chr11:62,690,262...62,727,384
Ensembl chr11:62,690,275...62,727,384
JBrowse link
G HP haptoglobin IEP RGD PMID:12540619 RGD:1626347 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G ICA1 islet cell autoantigen 1 ISO RGD PMID:7918678 RGD:633043 NCBI chr 7:8,113,184...8,262,687
Ensembl chr 7:8,113,184...8,262,687
JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP protein:increased expression:serum RGD PMID:19394054 RGD:2313467 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IGF1 insulin like growth factor 1 IEP mRNA,protein:decreased expression:corpus cavernosum: RGD PMID:22133301 RGD:10046054 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:16642022 RGD:2311506 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IL10 interleukin 10 IEP RGD PMID:22802947 RGD:7364853 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:18503494 RGD:2311530 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:serum,ovary RGD PMID:28412870 RGD:40400904 NCBI chr 9:6,214,591...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL6 interleukin 6 susceptibility IAGP
ISO
IEP
IDA
DNA:polymorphism:promoter:-174G>C (human)
mRNA:decreased expression:dendritic cell (mouse)
associated with Dementia; protein:increased expression:brain (human)
protein:increased expression:extracellular space (human)
RGD PMID:18689695 PMID:19120268 PMID:19139294 PMID:19442860 RGD:2307293, RGD:2307278, RGD:2307273, RGD:2307180 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin IDA
IAGP
EXP
ISO
IMP
protein:altered localization :endoplasmic reticulum
ClinVar Annotator: match by term: Diabetes mellitus
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Monogenic diabetes
DNA, protein:missense mutations:exons:multiple
DNA:point mutation (mouse)
DNA, protein:missense mutations, altered processing:exons, endoplasmic reticulum:multiple
ClinVar
CTD
RGD
PMID:2055425 PMID:7294224 PMID:7624867 PMID:8400068 PMID:11446671 More... RGD:2317260, RGD:2317259, RGD:2311115, RGD:2311109, RGD:2317262 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INS-IGF2 INS-IGF2 readthrough IAGP ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:17855560 PMID:18162506 PMID:18192540 PMID:20226046 PMID:25542748 More... NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G INSR insulin receptor IAGP DNA:deletions, missense mutation:multiple (human)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar
RGD
PMID:2040394 PMID:2211730 PMID:2983222 PMID:8257688 PMID:8432414 More... RGD:2307343 NCBI chr19:7,112,257...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G IRS1 insulin receptor substrate 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10591678 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
JBrowse link
G ITGA2 integrin subunit alpha 2 IDA protein:increased expression:monocyte (human) RGD PMID:17466965 RGD:2307424 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 susceptibility ISO DNA:deletion:exon:p.Q1715_R1731del (mouse) RGD PMID:21565852 RGD:6480678 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO
IAGP
TAS
DNA:mutation: :p.V59M (mouse)
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
Diabetes Mellitus, permanent neonatal, OMIM:606176
ClinVar
RGD
PMID:8897013 PMID:10338089 PMID:12524280 PMID:14715863 PMID:15115830 More... RGD:2311536, RGD:1625279, RGD:1625256 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
G KIF1A kinesin family member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
JBrowse link
G KIF5B kinesin family member 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425
JBrowse link
G KLF11 Kruppel like factor 11 IAGP ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15774581 PMID:17130512 PMID:18414213 PMID:18593768 PMID:19122346 More... NCBI chr 2:10,043,550...10,054,836
Ensembl chr 2:10,042,849...10,054,836
JBrowse link
G LEP leptin IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor IAGP
EXP
ClinVar Annotator: match by term: Monogenic diabetes
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15028607 PMID:25741868 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LMNA lamin A/C IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2007407 PMID:2270059 PMID:2526018 PMID:10587585 PMID:10655060 More... NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,573...156,140,081
JBrowse link
G LOC122094844 Sharpr-MPRA regulatory region 5730 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 NCBI chr 1:65,615,946...65,616,240 JBrowse link
G LRP1 LDL receptor related protein 1 treatment ISO RGD PMID:22889684 RGD:13800521 NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
JBrowse link
G MAFA MAF bZIP transcription factor A treatment ISO RGD PMID:23801580 RGD:13506744 NCBI chr 8:143,428,064...143,430,732
Ensembl chr 8:143,419,182...143,430,732
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16731828 NCBI chr 6:136,557,046...136,793,098
Ensembl chr 6:136,557,046...136,792,477
JBrowse link
G MARCO macrophage receptor with collagenous structure ISO protein:decreased expression:Alveolar macrophage RGD PMID:27630197 RGD:41412199 NCBI chr 2:118,942,180...118,994,664
Ensembl chr 2:118,942,194...118,994,660
JBrowse link
G MC4R melanocortin 4 receptor IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:9267995 PMID:10078568 PMID:10199800 PMID:10592235 PMID:10903341 More... NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775
JBrowse link
G MIR223 microRNA 223 IEP RNA:decreased expression:blood mononuclear cell RGD PMID:26717922 RGD:14398486 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MMP10 matrix metallopeptidase 10 IEP RGD PMID:11159210 RGD:8693313 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP3 matrix metallopeptidase 3 IEP mRNA:increased expression:retina RGD PMID:11159210 RGD:8693313 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18273840 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207
JBrowse link
G MT-ND4L mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L IAGP DNA:deletion: :m.8213_13992 (human) RGD PMID:7603516 RGD:5686343 NCBI chr MT:10,470...10,766
Ensembl chr MT:10,470...10,766
JBrowse link
G MT2A metallothionein 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association IAGP DNA:transition:cds:g.677C>T (human) RGD PMID:9607212 RGD:38501049 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G NAT2 N-acetyltransferase 2 IAGP DNA:polymorphism RGD PMID:16397907 RGD:2311597 NCBI chr 8:18,386,585...18,401,219
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
JBrowse link
G NEUROD1 neuronal differentiation 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827
JBrowse link
G NPPB natriuretic peptide B onset IEP RGD PMID:23733199 RGD:7246907 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO mRNA:increased expression:pancreatic islet RGD PMID:17259388 RGD:2311606 NCBI chr 1:26,911,489...26,914,110
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr 1:161,229,666...161,238,623
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G PAX4 paired box 4 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 7:127,610,292...127,618,142
Ensembl chr 7:127,610,292...127,618,142
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO
IAGP
mRNA, decreased expression:pancreatic islet (mouse)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar
RGD
PMID:10545530 PMID:10545531 PMID:10720084 PMID:11022198 PMID:11270685 More... RGD:2308812 NCBI chr13:27,919,982...27,926,313
Ensembl chr13:27,920,000...27,926,313
JBrowse link
G PLIN1 perilipin 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr15:89,664,365...89,679,367
Ensembl chr15:89,664,367...89,679,427
JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19153526 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PON1 paraoxonase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16229851 PMID:19022366 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISS MouseDO NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma EXP
IAGP
CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:16168052 PMID:19748282 PMID:25741868 PMID:27749844 PMID:28492532 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPP1R3A protein phosphatase 1 regulatory subunit 3A IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:12118251 PMID:25741868 PMID:28492532 NCBI chr 7:113,876,777...113,919,094
Ensembl chr 7:113,876,777...114,075,920
JBrowse link
G PROM1 prominin 1 ISO RGD PMID:11237753 RGD:68837 NCBI chr 4:15,968,226...16,084,059
Ensembl chr 4:15,963,076...16,084,378
JBrowse link
G PTEN phosphatase and tensin homolog ISO protein:increased expression, increased phosphorylation:inferior vena cava RGD PMID:16961925 RGD:2292543 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTF1A pancreas associated transcription factor 1a IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:25775927 PMID:28492532 NCBI chr10:23,192,312...23,194,245
Ensembl chr10:23,192,312...23,194,245
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15885672 PMID:15885672 RGD:5143927 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IAGP DNA: snp: cds: C1858T RGD PMID:18764813 RGD:6484729 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RAC1 Rac family small GTPase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RFX6 regulatory factor X6 IAGP ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15592663 PMID:18414213 PMID:20148032 PMID:25741868 PMID:28492532 More... NCBI chr 6:116,877,218...116,932,163
Ensembl chr 6:116,877,212...116,932,161
JBrowse link
G SERPINA7 serpin family A member 7 IEP RGD PMID:8742570 RGD:2312329 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO RGD PMID:10910004 RGD:2312393 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SHBG sex hormone binding globulin IEP protein:increased expression:plasma RGD PMID:18346991 RGD:2313784 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
JBrowse link
G SHLD2 shieldin complex subunit 2 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr10:87,094,478...87,191,468
Ensembl chr10:87,094,161...87,191,465
JBrowse link
G SIM1 SIM bHLH transcription factor 1 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2152513 PMID:16924270 PMID:21512513 PMID:23778136 PMID:23778139 More... NCBI chr 6:100,385,009...100,464,929
Ensembl chr 6:100,385,009...100,464,921
JBrowse link
G SIRT1 sirtuin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894401 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC19A2 solute carrier family 19 member 2 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar
RGD
PMID:25741868 PMID:28492532 PMID:10391221 RGD:1599325 NCBI chr 1:169,463,909...169,485,970
Ensembl chr 1:169,463,909...169,485,944
JBrowse link
G SLC22A12 solute carrier family 22 member 12 ISO protein:decreased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr11:64,591,219...64,603,250
Ensembl chr11:64,590,641...64,602,353
JBrowse link
G SLC2A1 solute carrier family 2 member 1 IEP RGD PMID:10022440 RGD:12879500 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC2A2 solute carrier family 2 member 2 IAGP ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:8027028 PMID:8063045 PMID:11810292 PMID:23986439 PMID:25741868 More... NCBI chr 3:170,996,341...171,026,721
Ensembl chr 3:170,996,347...171,026,743
JBrowse link
G SLC2A3 solute carrier family 2 member 3 IEP RGD PMID:10086067 RGD:2313619 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...7,936,187
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ameliorates ISO RGD PMID:15100317 RGD:151232286 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23786522 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD3 superoxide dismutase 3 IDA RGD PMID:12830380 RGD:1581299 NCBI chr 4:24,795,478...24,800,845
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 IAGP ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:10835640 PMID:15980664 PMID:16849362 PMID:18978175 PMID:23017645 More... NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671
JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 ISO RGD PMID:12749121 RGD:1600067 NCBI chr 2:31,522,480...31,665,651
Ensembl chr 2:31,522,480...31,580,938
JBrowse link
G TCF7L2 transcription factor 7 like 2 IAGP associated with Cystic Fibrosis;DNA:SNP (human) RGD PMID:19585101 RGD:2312417 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
G TFPI tissue factor pathway inhibitor IEP protein:increased expression:plasma: RGD PMID:8914465 RGD:11060253 NCBI chr 2:187,464,230...187,554,501
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G THBS2 thrombospondin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 6:169,215,785...169,253,846
Ensembl chr 6:169,215,780...169,254,050
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 IEP protein:decreased expression:glomerulus RGD PMID:19506087 RGD:2312464 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TLR4 toll like receptor 4 IEP
IAGP
protein:increased expression:monocyte RGD PMID:19210958 PMID:15632890 RGD:2312485, RGD:1580736 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO RGD PMID:10192335 RGD:2312735 NCBI chr 1:12,063,303...12,144,213
Ensembl chr 1:12,063,303...12,144,207
JBrowse link
G UCP3 uncoupling protein 3 IDA RGD PMID:17587402 RGD:2313514 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
JBrowse link
G VDR vitamin D receptor no_association IAGP DNA:SNPs: :rs731236, rs1544410, rs7975232 (human) RGD PMID:22856230 RGD:8158070 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G VWF von Willebrand factor treatment ISO RGD PMID:19722571 RGD:7207029 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein onset IAGP
ISO
DNA:missense mutations:cds:p.R456H, p.R611H (rs1801206, rs1801214) (human)
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar
RGD
PMID:10521293 PMID:10624825 PMID:10679252 PMID:11161832 PMID:11244483 More... RGD:8694404, RGD:149735331 NCBI chr 4:6,260,368...6,303,265
Ensembl chr 4:6,269,849...6,303,265
JBrowse link
G ZFP57 ZFP57 zinc finger protein EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:18414213 PMID:18622393 PMID:23748067 PMID:25741868 PMID:28492532 NCBI chr 6:29,672,392...29,681,152
Ensembl chr 6:29,672,483...29,681,155
JBrowse link
Diabetes Mellitus, Congenital Autoimmune term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12930356 NCBI chr 9:114,893,343...114,930,674
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
Diabetes Mellitus, New-Onset after Transplantation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTOR mechanistic target of rapamycin kinase IMP RGD PMID:22645144 RGD:10040997 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
diabetic angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme IAGP ClinVar Annotator: match by term: END-STAGE RENAL DISEASE, DIABETIC, SUSCEPTIBILITY TO ClinVar
OMIM
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ADCY3 adenylate cyclase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237
JBrowse link
G ADCY8 adenylate cyclase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 8:130,780,300...131,041,604
Ensembl chr 8:130,780,301...131,040,909
JBrowse link
G AGER advanced glycosylation end-product specific receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:20372816 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G ALB albumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19733855 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ASS1 argininosuccinate synthase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:25033204 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15878326 RGD:7241570 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G CASP3 caspase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23154660 RGD:11526153 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CD28 CD28 molecule IEP associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased expression:T cell RGD PMID:15504310 RGD:2307197 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:serum RGD PMID:14963650 RGD:2314223 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CREM cAMP responsive element modulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr10:35,126,841...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 susceptibility IAGP associated with Diabetic Foot;DNA:polymorphism:3' utr (human) RGD PMID:16723689 RGD:2306558 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G EPO erythropoietin IAGP ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar
OMIM
PMID:18458324 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:increased expression:plasma
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD PMID:9285207 PMID:16371118 RGD:2313868, RGD:2313861 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAS Fas cell surface death receptor IEP associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15803113 RGD:2315753 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand IEP
EXP
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25381014 PMID:15803113 RGD:2315753 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:12716757 RGD:1601179 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha IEP RGD PMID:21411989 RGD:7242686 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023
JBrowse link
G GPX1 glutathione peroxidase 1 IEP cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GSR glutathione-disulfide reductase IEP cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HFE homeostatic iron regulator IAGP ClinVar Annotator: match by term: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 7
ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO
OMIM
ClinVar
PMID:678784 PMID:8696333 PMID:8896549 PMID:8896550 PMID:8931958 More... NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HFE-AS1 HFE antisense RNA 1 IAGP ClinVar Annotator: match by term: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 7 ClinVar PMID:8696333 PMID:8896550 PMID:8943161 PMID:9106528 PMID:9162021 More... NCBI chr 6:26,086,290...26,091,034 JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP associated with Diabetes Mellitus Type 1;DNA:polymorphism: :HLA-DRB1*03:01(human) RGD PMID:23376458 RGD:7365114 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:16959961 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta RGD PMID:18093596 PMID:18796303 RGD:2306988, RGD:2313473 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 IAGP DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G IL1RN interleukin 1 receptor antagonist IAGP ClinVar Annotator: match by term: NEPHROPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar
OMIM
PMID:8500797 PMID:8786086 PMID:10025794 PMID:10746728 PMID:10750554 More... NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G MMP14 matrix metallopeptidase 14 IEP RGD PMID:12477149 RGD:1582581 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16681562 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G NOS2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea RGD PMID:19241604 PMID:19587355 RGD:4891384, RGD:2313210 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO
EXP
associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12124201 PMID:19241604 PMID:29329611 RGD:4891384, RGD:13504708 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased tyrosine phosphorylation:conceptus RGD PMID:10329590 RGD:2311657 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PLAT plasminogen activator, tissue type IDA associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:18945481 RGD:2311663 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G POLR1C RNA polymerase I and III subunit C IAGP ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar PMID:11978667 NCBI chr 6:43,517,089...44,461,400
Ensembl chr 6:43,509,702...43,562,419
JBrowse link
G PON1 paraoxonase 1 IAGP associated with Diabetes Mellitus;DNA:polymorphisms: p.L55M, p.Q192R (human)
ClinVar Annotator: match by term: RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO
OMIM
ClinVar
RGD
PMID:9011577 PMID:9661650 PMID:11335891 PMID:11788650 PMID:11889198 More... RGD:2313270 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PTK2B protein tyrosine kinase 2 beta treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21926342 RGD:10041069 NCBI chr 8:27,311,478...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G SERPINE1 serpin family E member 1 susceptibility IAGP associated with Diabetes Mellitus, Type 2;DNA:deletion, haplotype:promoter:g.-676_-674delG (human) RGD PMID:9844142 RGD:8547700 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERPINF1 serpin family F member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SOD1 superoxide dismutase 1 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IAGP ClinVar Annotator: match by term: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 6 OMIM
ClinVar
PMID:8633092 PMID:10425186 PMID:12624725 PMID:15591282 PMID:16538174 More... NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:mesentery, blood vessel RGD PMID:10625572 RGD:2300063 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G THBS1 thrombospondin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G THBS2 thrombospondin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 6:169,215,785...169,253,846
Ensembl chr 6:169,215,780...169,254,050
JBrowse link
G TNF tumor necrosis factor susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:c.-308G>A (human) RGD PMID:18575614 RGD:2313255 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G VEGFA vascular endothelial growth factor A ISO
IAGP
protein:increased expression:cochlea:
ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO
OMIM
ClinVar
RGD
PMID:11978667 PMID:19241604 RGD:4891384 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
Diabetic Cardiomyopathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21742475 RGD:10046044 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G ACE angiotensin I converting enzyme treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACOT1 acyl-CoA thioesterase 1 ISO associated with type 2 diabetes mellitus RGD PMID:23226270 RGD:13831128 NCBI chr14:73,493,021...73,543,799
Ensembl chr14:73,537,143...73,543,796
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr 1:202,940,825...202,958,572
Ensembl chr 1:202,940,826...202,958,572
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:heart (rat) RGD PMID:23251674 PMID:23251674 RGD:7244283, RGD:7244283 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGT angiotensinogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:29353218 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR2 angiotensin II receptor type 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15587404 PMID:16025228 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G APOA1 apolipoprotein A1 EXP CTD Direct Evidence: therapeutic CTD PMID:18332268 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO
EXP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16685413 PMID:21441944 RGD:6771209 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP7A ATPase copper transporting alpha treatment ISO RGD PMID:24927960 RGD:11341676 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21296063 RGD:10053697 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:myocardium (mouse)
RGD PMID:21296063 PMID:21474815 RGD:10053697, RGD:11522727 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) treatment ISO associated with Experimental Diabetes Mellitus RGD PMID:26869403 RGD:13782171 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CASQ2 calsequestrin 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21441944 RGD:6771209 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,714
JBrowse link
G CASR calcium sensing receptor ISO protein:decreased expression:myocardium (rat) RGD PMID:22137362 RGD:7205677 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G CFL1 cofilin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:27576917 RGD:11568692 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CTNNB1 catenin beta 1 ISO mRNA,protein:increased expression:heart RGD PMID:25586361 RGD:13524855 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23853776 PMID:23453443 RGD:9586347, RGD:10412713 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IGF1 insulin like growth factor 1 EXP CTD Direct Evidence: therapeutic CTD PMID:11375343 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23843977 RGD:7247697 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G INS insulin EXP CTD Direct Evidence: therapeutic CTD PMID:20828608 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G KLK1 kallikrein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:16129698 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MYLK2 myosin light chain kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:9005973 RGD:1580244 NCBI chr20:31,819,356...31,834,684
Ensembl chr20:31,819,308...31,834,689
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23453443 PMID:23353773 RGD:10412713, RGD:10412721 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29274332 RGD:13504685 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPPA natriuretic peptide A treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23497378 RGD:7297056 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NRG1 neuregulin 1 ISO associated with Diabetes Mellitus, Experimental;protein:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:heart left ventricle RGD PMID:22185592 RGD:7327207 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO RGD PMID:19317897 RGD:5509944 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G RYR2 ryanodine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16685413 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SLC25A4 solute carrier family 25 member 4 EXP CTD Direct Evidence: therapeutic CTD PMID:18945756 NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382
JBrowse link
G SLC8A1 solute carrier family 8 member A1 treatment ISO RGD PMID:27058979 RGD:13628396 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G SPP1 secreted phosphoprotein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16980342 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TERT telomerase reverse transcriptase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21264070 RGD:11038677 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:17909696 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23843977 RGD:7247697 NCBI chr 2:31,334,320...31,414,777
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
diabetic cataract term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSR glutathione-disulfide reductase IEP RGD PMID:12518238 RGD:10401829 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
Diabetic Cystopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nuclei: RGD PMID:20879002 RGD:10053565 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23129268 RGD:10053664 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:urinary bladder detrusor smooth muscle RGD PMID:26370333 RGD:13782173 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
Diabetic Embryopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain ISO RGD PMID:26419589 RGD:13792560 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
JBrowse link
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23529380 PMID:24291733 RGD:7244255, RGD:8553040 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G APP amyloid beta precursor protein treatment ISO associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G IDE insulin degrading enzyme IEP associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096
JBrowse link
G NGF nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NGFR nerve growth factor receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
Diabetic Foot term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP protein:decreased expression:plasma RGD PMID:20836881 RGD:5686889 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP associated with Diabetes Mellitus, Type 2;protein:decreased expression:blood RGD PMID:21941211 RGD:6767555 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G CRP C-reactive protein disease_progression IEP protein:increased expression:blood: RGD PMID:22712631 RGD:6906887 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G GJA1 gap junction protein alpha 1 IEP protein:increased expression:dermis RGD PMID:22455314 RGD:7207269 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B severity IAGP DNA:polymorphism: :1538G>A (human) RGD PMID:19731315 RGD:8662463 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G IGF1 insulin like growth factor 1 IEP protein:decreased expression:fibroblast of dermis,stratum basale of epidermis: RGD PMID:10727985 RGD:8549356 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL15 interleukin 15 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:dermis, endothelial cell RGD PMID:17014667 RGD:2313575 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
JBrowse link
G MBL2 mannose binding lectin 2 IEP protein:increased expression:serum: RGD PMID:19997692 RGD:8694068 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MMP9 matrix metallopeptidase 9 severity IEP RGD PMID:22688339 RGD:8547813 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G PLAT plasminogen activator, tissue type IDA RGD PMID:17275886 RGD:2311669 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PTX3 pentraxin 3 IEP protein:decreased expression:plasma (human) RGD PMID:30767386 RGD:38501100 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
JBrowse link
G TLR4 toll like receptor 4 susceptibility IAGP DNA:SNPs,haplotype: :rs4986790,rs4986791,rs10759931,rs1927911(human); RGD PMID:23936790 RGD:7777174 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
diabetic ketoacidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP2 aquaporin 2 IEP RGD PMID:12021537 RGD:2314345 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
JBrowse link
G INS insulin EXP CTD Direct Evidence: therapeutic CTD PMID:11430560 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INSR insulin receptor ISO RGD PMID:15254588 RGD:1302526 NCBI chr19:7,112,257...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G PAX4 paired box 4 susceptibility IAGP ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone, susceptibility to ClinVar
OMIM
PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 7:127,610,292...127,618,142
Ensembl chr 7:127,610,292...127,618,142
JBrowse link
G SERPINA7 serpin family A member 7 IEP protein:decreased expression:serum RGD PMID:6768790 RGD:2312332 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727
JBrowse link
Diabetic Nephropathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment
no_association
susceptibility
ISO
EXP
IAGP
IEA
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:insertion/deletion
associated with Diabetes Mellitus, Type 1;DNA:insertion/deletion
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
CTD
RGD
PMID:7909524 PMID:10099885 PMID:10857950 PMID:23733546 PMID:19301230 More... RGD:2311449, RGD:11039044, RGD:8548885, RGD:8548872, RGD:7829780, RGD:7829777, RGD:1331525 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 no_association IEP
EXP
ISO
IAGP
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:decreased expression:kidney
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple (human)
mRNA, protein:altered expression:kidney
CTD
RGD
PMID:12623933 PMID:17600118 PMID:20844835 PMID:19034303 PMID:18235039 More... RGD:2313797, RGD:2313800, RGD:2313800, RGD:2313796 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACVR1 activin A receptor type 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:11675415 RGD:2313802 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing disease_progression
no_association
IEP
EXP
IAGP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1501299 (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs2241766 (human)
CTD
RGD
PMID:17942768 PMID:21945031 PMID:17970779 PMID:23260797 PMID:23260797 RGD:5686409, RGD:8694475, RGD:8694443, RGD:8694443 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADORA1 adenosine A1 receptor ISO associated with Diabetes Mellitus, Experimental RGD PMID:19552053 RGD:2313803 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADRA2B adrenoceptor alpha 2B IAGP associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism (human) RGD PMID:15660746 RGD:2313545 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571
JBrowse link
G ADRB3 adrenoceptor beta 3 IAGP associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9867224 RGD:5684403 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility
treatment
ISO
IAGP
IEP
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney cortex, glomerulus
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1704G>T (human)
associated with Diabetes Mellitus;DNA:polymorphisms, haplotype:cds, intron:p.G82S, g.2184A>G (rs2070600, rs3134940) (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;protein:increased expression:renal cortex (mouse)
RGD PMID:19142024 PMID:14747204 PMID:21533139 PMID:23091285 PMID:12651605 More... RGD:2325651, RGD:8695982, RGD:7244187, RGD:7244174, RGD:7243248, RGD:7243852, RGD:7243248 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGT angiotensinogen disease_progression
no_association
IEA
EXP
IAGP
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :p.M235T (human)
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)
CTD
RGD
PMID:17890855 PMID:20383342 PMID:15118671 PMID:19014923 PMID:11938025 More... RGD:1331525, RGD:11039058, RGD:8548885, RGD:8548872, RGD:8548868 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO
IAGP
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1166A>C (human)
RGD PMID:12172324 PMID:12476891 RGD:6903861, RGD:8548891 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:18565281 RGD:6903847 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G AHSG alpha 2-HS glycoprotein IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15698447 RGD:2313813 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility IEP
IAGP
associated with Diabetes Mellitus, Type 1;DNA:promoter:repeat:g.?(AC)n (human) RGD PMID:9215310 PMID:9000706 RGD:734542, RGD:8548641 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G ALB albumin ISO
EXP
IEP
associated with Metabolic Syndrome X;protein:increased expression:urine
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD
RGD
PMID:16380483 PMID:19424163 PMID:21441310 PMID:19246226 PMID:19397971 RGD:2306882, RGD:5135032, RGD:2306886, RGD:2306885 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALPK1 alpha kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621
JBrowse link
G AOC3 amine oxidase copper containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14977883 NCBI chr17:42,851,182...42,858,130
Ensembl chr17:42,851,184...42,858,130
JBrowse link
G APOA1 apolipoprotein A1 IEP RGD PMID:9829487 RGD:2313960 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA2 apolipoprotein A2 IEP associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:9829487 PMID:11126402 RGD:2313960, RGD:2313958 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOB apolipoprotein B IEP associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19324028 RGD:2313979 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOC1 apolipoprotein C1 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:very-low-density lipoprotein particle RGD PMID:12753304 RGD:2313950 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
JBrowse link
G APOC3 apolipoprotein C3 IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-455T>C RGD PMID:16813599 RGD:2306755 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G APOE apolipoprotein E susceptibility
no_association
IAGP
ISO
DNA:missense mutations, haplotype:cds:p.C112R, p.R158C (human)
associated with Diabetes Mellitus, type 1;
associated with Diabetes Mellitus, Experimental
RGD PMID:21127830 PMID:11495633 PMID:22859852 RGD:6903840, RGD:7771553, RGD:6902935 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOH apolipoprotein H IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:11302005 RGD:2313989 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G AQP2 aquaporin 2 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased secretion:urine RGD PMID:12218327 RGD:2314343 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
JBrowse link
G ARG2 arginase 2 ISO RGD PMID:21926276 RGD:6902923 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta treatment ISO mRNA:decreased expression:renal glomerulus (rat) RGD PMID:22591908 RGD:13792578 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G AXL AXL receptor tyrosine kinase TAS
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12644472 PMID:15619028 RGD:1579938 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766
JBrowse link
G AZIN1 antizyme inhibitor 1 treatment ISO RGD PMID:26751697 RGD:14700801 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864
JBrowse link
G BDKRB2 bradykinin receptor B2 susceptibility ISO associated with Diabetes Mellitus, Experimental RGD PMID:17596525 RGD:2313335 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:20557422 RGD:4891134 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:kidney RGD PMID:21866636 RGD:6483069 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP associated with Diabetes Mellitus, Type2; protein:increased expression:serum: RGD PMID:9347246 RGD:7207424 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO RGD PMID:17437042 RGD:2289036 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G C3 complement C3 ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:kidney:
associated with Diabetes Mellitus, Type 2
RGD PMID:19200691 PMID:25662584 RGD:7183082, RGD:11040807 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C5 complement C5 ISO associated with Diabetes Mellitus, Type 2 RGD PMID:25662584 RGD:11040807 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B treatment ISO RGD PMID:27273361 RGD:13506726 NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
JBrowse link
G CAPN10 calpain 10 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22012129 RGD:7247733 NCBI chr 2:240,586,734...240,599,104
Ensembl chr 2:240,586,734...240,617,705
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 treatment ISO associated with Diabetes Mellitus, Experimental;protein:increased activity:kidney
associated with Diabetes Mellitus, Experimental
associated with type 2 diabetes mellitus
RGD PMID:19601660 PMID:29606028 PMID:28456626 RGD:2311440, RGD:13792586, RGD:13782304 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 treatment ISO associated with type 2 diabetes mellitus RGD PMID:28456626 RGD:13782304 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 treatment ISO associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:28456626 PMID:29606028 RGD:13782304, RGD:13792586 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:30038056 PMID:29606028 RGD:13782342, RGD:13792586 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase ISO rat gene in db/db mice
associated with experimentally induced diabetes
RGD PMID:22315314 PMID:20299359 PMID:21525431 PMID:21686137 RGD:7205651, RGD:7205676, RGD:7205665, RGD:7205662 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL11 C-C motif chemokine ligand 11 IEP associated with Diabetes Mellitus, Type 2 RGD PMID:21113841 RGD:5683918 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 susceptibility
disease_progression
ISO
EXP
IEP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
protein:increased expression:urine
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
CTD
RGD
PMID:16374426 PMID:17968528 PMID:19409809 PMID:19369290 PMID:19097668 More... RGD:2306991, RGD:2306979, RGD:2306980, RGD:2306982, RGD:2306989 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17664181 RGD:7483629 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility IAGP
IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-28C>G
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:urine
RGD PMID:12610055 PMID:18326229 RGD:2307107, RGD:2307063 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCN2 cellular communication network factor 2 ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney, glomerulus (rat)
RGD PMID:19065061 PMID:19895808 RGD:2314604, RGD:2314366 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCNE1 cyclin E1 ISO protein:increased expression:kidney RGD PMID:17825795 RGD:2289273 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CCR2 C-C motif chemokine receptor 2 no_association IAGP
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.V64I (human)
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:11756347 PMID:17631861 RGD:2313563, RGD:2313558 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR5 C-C motif chemokine receptor 5 susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:59029G>A (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :59029G>A (human)
RGD PMID:12610055 PMID:17428349 RGD:2307107, RGD:8549756 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CD36 CD36 molecule ISO protein:increased expression:renal proximal tubule, endothelial cell RGD PMID:15737001 RGD:2307215 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD38 CD38 molecule IDA
ISO
associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:19300526 PMID:19073639 RGD:2307228, RGD:2307227 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CD40LG CD40 ligand IEP associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:serum RGD PMID:18756582 RGD:2314208 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:27652271 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:increased expression:kidney
mRNA, protein:increased expression:kidney, glomerulus
RGD PMID:16805985 PMID:15698433 RGD:2293619, RGD:2293628 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CFL1 cofilin 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:renal glomerulus (rat) RGD PMID:24726496 RGD:11570419 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CLU clusterin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:18949565 RGD:9068414 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G CNDP1 carnosine dipeptidase 1 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17942768 PMID:21393041 PMID:21573905 PMID:21393041 RGD:7207213 NCBI chr18:74,534,500...74,587,212
Ensembl chr18:74,534,500...74,587,212
JBrowse link
G CNDP2 carnosine dipeptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21573905 NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus (rat) RGD PMID:22903132 RGD:8552684 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL4A1 collagen type IV alpha 1 chain ISO
EXP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA:increased expression:kidney
CTD
RGD
PMID:18682491 PMID:27997345 PMID:17582205 PMID:19466391 RGD:2311342, RGD:2311340 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157
JBrowse link
G CPB2 carboxypeptidase B2 susceptibility IAGP
IEP
DNA:SNP:cds:1040C>T(human)
protein:increased expression:plasma
RGD PMID:22932273 PMID:12574207 RGD:7243116, RGD:7243123 NCBI chr13:46,053,066...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G CREB1 cAMP responsive element binding protein 1 susceptibility ISO RGD PMID:15862029 RGD:10059365 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRP C-reactive protein disease_progression IDA
IEP
associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
RGD PMID:22885250 PMID:22590912 RGD:6906965, RGD:6906967 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF1R colony stimulating factor 1 receptor disease_progression ISO associated with Diabetes Mellitus, Type 2 RGD PMID:19466391 RGD:2311340 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CST3 cystatin C ISO
IEP
protein:increased expression:plasma (rat)
protein:increased expression:serum (human)
RGD PMID:18946178 PMID:19132849 RGD:2314297, RGD:2314328 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:plasma: RGD PMID:18026823 RGD:2312302 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G CUBN cubilin ISO RGD PMID:17037740 RGD:1599655 NCBI chr10:16,823,966...17,130,492
Ensembl chr10:16,823,966...17,129,811
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:17425653 PMID:19073786 RGD:2311359, RGD:2311357 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22791342 RGD:7257674 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CYBA cytochrome b-245 alpha chain IAGP associated with Diabetes Mellitus, Type 2;DNA:SNP: :242C>T (human) RGD PMID:14747204 RGD:8695982 NCBI chr16:88,643,289...88,651,079
Ensembl chr16:88,643,289...88,651,054
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-344C>T (human) RGD PMID:16672053 RGD:2307295 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22301628 RGD:7257708 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 IDA associated with Diabetes Mellitus, Experimental; RGD PMID:21742052 RGD:7243153 NCBI chr 1:59,893,308...59,926,773
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G DCN decorin IEP
ISO
IAGP
protein:increased expression:plasma, urine
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;mRNA, protein:decreased expression:kidney cortex, glomerulus
RGD PMID:11259366 PMID:17884968 PMID:16868749 PMID:12187087 RGD:2311416, RGD:2311411, RGD:2311412, RGD:2311415 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DGKH diacylglycerol kinase eta EXP CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr13:42,040,070...42,256,584
Ensembl chr13:42,040,036...42,256,578
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20019166 RGD:6907383 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G EDN1 endothelin 1 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased secretion:plasma (human) RGD PMID:18346810 RGD:2313284 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDNRA endothelin receptor type A ISO associated with Diabetes Mellitus, Experimental RGD PMID:21191784 RGD:4892326 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EGF epidermal growth factor IEP RGD PMID:17475821 RGD:6906912 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G ELMO1 engulfment and cell motility 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17942768 NCBI chr 7:36,852,906...37,449,326
Ensembl chr 7:36,852,906...37,449,223
JBrowse link
G ENG endoglin IEP associated with Diabetes Mellitus, Insulin-Dependent; mRNA:increased expression:kidney RGD PMID:19395281 RGD:2313795 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IAGP RGD PMID:19506043 RGD:6906926 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G EP300 E1A binding protein p300 treatment ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat) RGD PMID:19268536 PMID:19268536 RGD:2311716, RGD:2311716 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17967803 PMID:17914354 RGD:10395374, RGD:10395377 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21832210 RGD:5688728 NCBI chr 8:27,491,143...27,597,559
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin IAGP
IEP
IDA
DNA:snp:promoter:-1125T>G(rs1617640)(human)
Protein:decreased expression:serum
associated with Diabetes Mellitus, Experimental;
RGD PMID:18458324 PMID:19619913 PMID:19356735 RGD:2313838, RGD:2313832, RGD:2313833 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney: RGD PMID:10749885 RGD:9685546 NCBI chr 1:8,011,725...8,026,309
Ensembl chr 1:8,004,404...8,026,309
JBrowse link
G ESR1 estrogen receptor 1 ISO
IAGP
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:snps:introns: multiple(human)
RGD PMID:16464734 PMID:18305958 RGD:2314020, RGD:2314005 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G F2 coagulation factor II, thrombin disease_progression IEP
IAGP
protein:increased expression:plasma (human)
DNA:polymorphism: :20210G>A(human)
RGD PMID:21955218 PMID:14983223 PMID:21574459 RGD:6893574, RGD:2313643, RGD:6893575 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:15004866 RGD:2313863 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FABP2 fatty acid binding protein 2 IAGP DNA:polymorphism:CDS:amino acid A54T, in a Brazilian population RGD PMID:16249461 RGD:1578457 NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
JBrowse link
G FAS Fas cell surface death receptor IEP
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney
associated with Diabetes Mellitus, Experimental;protein:increased expression:renal distal tubule (rat)
mRNA:increased expression:kidney
RGD PMID:17851466 PMID:12861046 PMID:18287563 RGD:2315705, RGD:8686421, RGD:2312739 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand IEP associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney RGD PMID:17851466 RGD:2315705 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FBN1 fibrillin 1 onset ISO associated with Diabetes Mellitus, Experimental RGD PMID:16395273 PMID:16380460 RGD:7365077, RGD:7365080 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721
JBrowse link
G FGF2 fibroblast growth factor 2 IEP mRNA:increased expression:kidney RGD PMID:19279131 RGD:2315842 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGF21 fibroblast growth factor 21 IEP protein:increased expression:serum: RGD PMID:25625802 RGD:10401920 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
JBrowse link
G FGF23 fibroblast growth factor 23 severity ISO mRNA,protein:increased expression:kidney: RGD PMID:23967103 RGD:10044235 NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine RGD PMID:15610240 RGD:2313731 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G FMOD fibromodulin ISO
IEP
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:decreased expression:kidney cortex
mRNA,protein:increased expression:Kidney Glomerulus
RGD PMID:16868749 PMID:11259366 RGD:2311412, RGD:2311416 NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758
JBrowse link
G FN1 fibronectin 1 treatment ISO
EXP
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney cortex:
CTD
RGD
PMID:24413998 PMID:16301823 PMID:22736507 RGD:7206843, RGD:10402169 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FUCA1 alpha-L-fucosidase 1 IEP associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased activity;urine RGD PMID:8343614 RGD:2315943 NCBI chr 1:23,845,077...23,868,332
Ensembl chr 1:23,845,077...23,868,290
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO associated with Hypertension RGD PMID:21987533 RGD:10449128 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GAS6 growth arrest specific 6 TAS
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12644472 PMID:15619028 RGD:1579938 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076
JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 IEP RGD PMID:9519709 RGD:2313353 NCBI chr 2:69,319,780...69,387,227
Ensembl chr 2:69,319,780...69,387,250
JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP:3' utr RGD PMID:14764791 RGD:2307362 NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,698...180,353,336
JBrowse link
G GHR growth hormone receptor susceptibility ISO associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:10541297 PMID:15066219 PMID:10990443 PMID:10614635 RGD:2307370, RGD:2307364, RGD:2307368, RGD:2307369 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
JBrowse link
G GIPR gastric inhibitory polypeptide receptor IMP RGD PMID:19211686 RGD:2306734 NCBI chr19:45,668,187...45,683,722
Ensembl chr19:45,668,221...45,683,722
JBrowse link
G GLO1 glyoxalase I IAGP DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003 RGD:7242569 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
JBrowse link
G GPX1 glutathione peroxidase 1 ISO
IAGP
protein:increased expression:glomerulus
associated with Diabetes Mellitus, Type 1
RGD PMID:17609286 PMID:16249459 RGD:2306609, RGD:11068479 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GPX3 glutathione peroxidase 3 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:serum (human) RGD PMID:17269729 RGD:2312635 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr11:67,266,420...67,286,556
Ensembl chr11:67,266,473...67,286,556
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr22:25,564,675...25,729,294
Ensembl chr22:25,564,675...25,729,294
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO protein:decreased expression:cortex of kidney (rat) RGD PMID:23196710 RGD:13792785 NCBI chr 4:2,963,504...3,040,760
Ensembl chr 4:2,963,571...3,040,760
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr 5:177,426,496...177,442,891
Ensembl chr 5:177,403,204...177,442,901
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:26888388 RGD:13792773 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSR glutathione-disulfide reductase treatment IEP
ISO
associated with Diabetes Mellitus, Type 2;protein:decreased activity:kidney
associated with Diabetes Mellitus, Experimental
RGD PMID:23626958 PMID:24947049 RGD:7257582, RGD:10401899 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 no_association IAGP associated with Diabetes Mellitus, Type 1;DNA:deletion:cds: (human) RGD PMID:19752172 RGD:7495818 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 disease_progression
no_association
IAGP associated with Diabetes Mellitus, Type 2;DNA:deletion:cds (human)
associated with Diabetes Mellitus, Type 1;DNA:deletion:cds (human)
RGD PMID:15927971 PMID:19752172 RGD:2306630, RGD:7495818
G HAS2 hyaluronan synthase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal medulla RGD PMID:18441392 RGD:9588630 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO
IEP
protein:increased expression:plasma
associated with Diabetes mellitus, Type 1;
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
RGD PMID:22997966 PMID:20980978 PMID:22015481 RGD:7245497, RGD:7246890, RGD:7245960 NCBI chr 5:157,028,383...157,069,633
Ensembl chr 5:157,029,413...157,059,119
JBrowse link
G HDAC2 histone deacetylase 2 ISO
IEP
mRNA,protein:increased expression:kidney: RGD PMID:24717296 PMID:24717296 PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC4 histone deacetylase 4 treatment ISO
IEP
mRNA,protein:increased expression:kidney: RGD PMID:24717296 PMID:24717296 PMID:24717296 PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G HDAC5 histone deacetylase 5 ISO
IEP
mRNA,protein:increased expression:kidney: RGD PMID:24717296 PMID:24717296 PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr17:44,076,753...44,123,651
Ensembl chr17:44,076,746...44,123,702
JBrowse link
G HFE homeostatic iron regulator IAGP associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HGF hepatocyte growth factor IMP RGD PMID:16340242 RGD:2313567 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17967803 PMID:17914354 RGD:10395374, RGD:10395377 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21849637 RGD:10755581 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,432,845
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A IAGP associated with Diabetes Mellitus, Type 2 RGD PMID:18518860 RGD:7242747 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B IAGP RGD PMID:18518860 RGD:7242747 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:17330940 RGD:7242762 NCBI chr11:123,057,489...123,062,366
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO
IEP
mRNA,protein:increased expression:glomerulus:
protein:increased expression:glomerulus, podocyte:
RGD PMID:21931298 PMID:21931298 RGD:10402764, RGD:10402764 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO
IMP
associated with Diabetes Mellitus, Experimental;
associated with Diabetes Mellitus Type 2;
RGD PMID:18175064 PMID:12213354 RGD:7257686, RGD:7257687 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO
IEP
IAGP
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney (mouse)
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.K469E (rs5498) (human)
RGD PMID:20447389 PMID:19246972 PMID:18299691 PMID:18505543 RGD:4145414, RGD:2313470, RGD:2312766, RGD:2313475 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma ISO mRNA, protein:increased expression:kidney, T cell RGD PMID:22286547 RGD:6893364 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1 insulin like growth factor 1 IEP
ISO
protein:decreased expression:serum
associated with Diabetes Mellitus, Experimental;protein:decreased expression:serum (rat)
RGD PMID:17194636 PMID:10444029 RGD:2313764, RGD:12904967 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA,protein:increased expression:kidney: RGD PMID:19008912 RGD:10046022 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGF2 insulin like growth factor 2 ISO
IDA
associated with Diabetes Mellitus, Type 2; mRNA:decreased expression:neural tissue, liver:
associates with Diabetes Mellitus; mRNA:decreased expression:brain:
RGD PMID:9336345 PMID:8764603 PMID:9336345 RGD:5510019, RGD:5510022, RGD:5510019 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 IAGP DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G IL10 interleukin 10 susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 RGD:2308943 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:22086159 PMID:19769609 RGD:7175266, RGD:7175519 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
no_association
IAGP associated with Diabetes Mellitus, Type 2; DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:16174285 PMID:17286233 RGD:6907371, RGD:6909120 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL6 interleukin 6 susceptibility IDA
IAGP
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney (rat)
RGD PMID:18716362 PMID:19542902 PMID:19052104 RGD:2307282, RGD:7829816, RGD:2307281 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin resistance ISO
EXP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:2143390 PMID:7713310 PMID:7987072 PMID:22068113 RGD:6902908 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G IRS2 insulin receptor substrate 2 IEP mRNA:increased expression:kidney tubule: RGD PMID:23617393 RGD:7257702 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
JBrowse link
G ITGA2 integrin subunit alpha 2 severity IDA associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:mesangial cell (human) RGD PMID:8989742 RGD:2307420 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KDM6A lysine demethylase 6A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chr  X:44,873,182...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KDR kinase insert domain receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:18630688 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:21439372 RGD:6893386 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KL klotho treatment ISO protein:decreased expression:kidney: RGD PMID:24136780 RGD:10403079 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G KLK1 kallikrein 1 IDA
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:19516248 PMID:17272402 RGD:1641794 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G KLKB1 kallikrein B1 disease_progression IEP associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G KNG1 kininogen 1 IAGP associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :7965C>T (human) RGD PMID:17065357 RGD:2311541 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G LAMB2 laminin subunit beta 2 ISO RGD PMID:19864299 RGD:7207449 NCBI chr 3:49,121,114...49,133,066
Ensembl chr 3:49,121,114...49,133,118
JBrowse link
G LCN2 lipocalin 2 ISO
IEP
protein:increased expression:urine
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
RGD PMID:22997966 PMID:22015481 RGD:7245497, RGD:7245960 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LEP leptin ISO RGD PMID:22773754 RGD:6907074 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28130181 PMID:29988851 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LMNA lamin A/C IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:cds:1908C>T (human) RGD PMID:16117820 RGD:2306095 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,573...156,140,081
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase IEP RGD PMID:1789335 RGD:2311543 NCBI chr 5:96,934,859...97,037,513
Ensembl chr 5:96,935,394...97,037,513
JBrowse link
G LPL lipoprotein lipase susceptibility IAGP RGD PMID:16813599 RGD:2306755 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G LTA lymphotoxin alpha IAGP DNA:polymorphism RGD PMID:18575614 RGD:2313255 NCBI chr 6:31,560,550...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEP RGD PMID:19923143 RGD:7243957 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activity:kidney RGD PMID:19066844 RGD:2311566 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MDK midkine EXP CTD Direct Evidence: marker/mechanism CTD PMID:17607302 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837
JBrowse link
G MFN2 mitofusin 2 treatment ISO
EXP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:27997345 PMID:27997345 PMID:26123583 RGD:12910740, RGD:11053290 NCBI chr 1:11,980,215...12,013,508
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MIR145 microRNA 145 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24223694 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G MIR146A microRNA 146a exacerbates ISO RGD PMID:26647423 RGD:126925142 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression:kidney RGD PMID:30847937 RGD:41410820 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MLLT3 MLLT3 super elongation complex subunit treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23077601 RGD:9686143 NCBI chr 9:20,341,669...20,622,499
Ensembl chr 9:20,341,669...20,622,499
JBrowse link
G MMP12 matrix metallopeptidase 12 IAGP RGD PMID:21277817 RGD:7241216 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23384615 RGD:13204971 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 IEP protein: decreased expression: glomerulus RGD PMID:9211353 RGD:7241249 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment IAGP
ISO
associated with Diabetes Mellitus, Type 2;DNA:repeat:promoter
associated with Diabetes Mellitus, Experimental
RGD PMID:11576356 PMID:23384615 RGD:8547866, RGD:13204971 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
no_association
IAGP associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:14737040 PMID:18280442 RGD:6893524, RGD:6893576 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTOR mechanistic target of rapamycin kinase susceptibility ISO
IAGP
DNA:SNP,haplotype: :rs7212142(human)
associated with Diabetes Mellitus, Experimental
RGD PMID:21606597 PMID:28536139 PMID:23827786 RGD:7245564, RGD:13506787, RGD:10003168 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase IAGP Associated with Diabetes Mellitus, Type 1;DNA:SNP:cds:66A>G, (rs1801394) (human) RGD PMID:18774994 RGD:6893652 NCBI chr 5:7,851,186...7,901,124
Ensembl chr 5:7,851,186...7,906,025
JBrowse link
G NAT2 N-acetyltransferase 2 IAGP associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:10591543 RGD:2311598 NCBI chr 8:18,386,585...18,401,219
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 treatment ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney,glomerulus
associated with Diabetes Mellitus, Experimental
RGD PMID:22903132 PMID:22591908 RGD:8552684, RGD:13792578 NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO
EXP
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:20103708 PMID:21439372 PMID:23064900 RGD:6893386, RGD:10412718 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NOS1 nitric oxide synthase 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:23548923 PMID:10966937 RGD:7257655, RGD:13824991 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
treatment
no_association
IAGP
EXP
ISO
associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:20042665 PMID:10868974 PMID:29336891 PMID:10741691 RGD:7421530, RGD:13504726, RGD:7421534 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOX4 NADPH oxidase 4 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney cortex
RGD PMID:16135519 PMID:17511984 RGD:2324673, RGD:2324670 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:decreased expression:kidney (mouse)
RGD PMID:17624267 PMID:21617141 PMID:24173355 PMID:30862474 RGD:38596322, RGD:7241083, RGD:38599008, RGD:38596325 NCBI chr19:35,862,915...35,869,287
Ensembl chr19:35,825,964...35,869,287
JBrowse link
G NPPA natriuretic peptide A no_association
disease_progression
ISO
IEP
IAGP
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:blood
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
DNA:polymorphism:intron
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :2238T>C (human)
RGD PMID:10381153 PMID:10404802 PMID:9681733 PMID:15111511 RGD:2313592, RGD:7247731, RGD:2313593, RGD:2313590 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B IEP
ISO
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:10404802 PMID:16917760 RGD:7247731, RGD:7248603 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21457706 RGD:11035226 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:20557422 RGD:4891134 NCBI chr 9:84,668,458...85,027,070
Ensembl chr 9:84,668,375...85,095,751
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20621183 RGD:11073737 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PAX2 paired box 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney cortex RGD PMID:15149326 RGD:2316747 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PDGFA platelet derived growth factor subunit A IEP associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:increased expression:kidney RGD PMID:12808179 RGD:2311649 NCBI chr 7:497,245...520,700
Ensembl chr 7:497,258...520,296
JBrowse link
G PDGFB platelet derived growth factor subunit B IEP associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRB platelet derived growth factor receptor beta IEP associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:glomerulus RGD PMID:15042541 RGD:2311655 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PGF placental growth factor disease_progression IEP associated with Diabetes Mellitus, Type 1 RGD PMID:21988672 RGD:6483606 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PLAT plasminogen activator, tissue type IEP associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16598198 RGD:2311671 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:renal glomerulus (rat) RGD PMID:15322501 RGD:1580123 NCBI chr10:73,909,182...73,917,497
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PON1 paraoxonase 1 no_association
susceptibility
IDA
EXP
IAGP
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus;DNA:missense mutations:cds:p.L55M, p.Q192R (rs854560, rs662) (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
CTD
RGD
PMID:26884296 PMID:19207863 PMID:24100645 PMID:15270786 RGD:2313266, RGD:8547572, RGD:8547548 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PON2 paraoxonase 2 IAGP associated with type 1 diabetes mellitus;DNA:missense mutation:cds:p.C311S (human)
associated with type 2 diabetes mellitus;DNA:polymorphisms:multiple
RGD PMID:11918623 PMID:11206400 RGD:1580218, RGD:2313492 NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
JBrowse link
G POSTN periostin ISO mRNA,protein:increased expression:kidney: RGD PMID:22167593 RGD:10040972 NCBI chr13:37,562,585...37,598,839
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO
EXP
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD
RGD
PMID:28182703 PMID:18780770 PMID:18388116 RGD:2301845, RGD:2301862 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha IEP
IAGP
mRNA:decreased expression:kidney (human)
DNA:polymorphism:exon:p.G482S (human)
RGD PMID:21784897 PMID:19900151 RGD:7242027, RGD:7242045 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRKCB protein kinase C beta ISO associated with hypertension;protein:increased expression:glomerular mesangium RGD PMID:12540629 RGD:729635 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCE protein kinase C epsilon EXP CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr 2:45,651,315...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PRMT1 protein arginine methyltransferase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23159951 RGD:9491822 NCBI chr19:49,676,166...49,688,447
Ensembl chr19:49,675,786...49,689,029
JBrowse link
G PROS1 protein S severity
treatment
ISO
IEP
IMP
associated with diabetes mellitus, experimental
associated with diabetes mellitus, experimental;mRNA, protein:increased expression:kidney, glomerulus
RGD PMID:29511111 PMID:29511111 PMID:29511111 PMID:29511111 RGD:13515131, RGD:13515131, RGD:13515131, RGD:13515131 NCBI chr 3:93,873,051...93,973,896
Ensembl chr 3:93,873,051...93,980,003
JBrowse link
G PRSS1 serine protease 1 IEP protein:increased expression:urine RGD PMID:18428024 RGD:2324899 NC