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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:glucose metabolism disease
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Accession:DOID:4194 term browser browse the term
Definition:Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM.
Synonyms:exact_synonym: Glucose Metabolic Disorder;   Glucose Metabolic Disorders;   Glucose Metabolism Disorder;   Glucose Metabolism Disorders;   disorder of glucose metabolism
 primary_id: MESH:D044882;   RDO:0002537
 xref: NCI:C53655
For additional species annotation, visit the Alliance of Genome Resources.


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glucose metabolism disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29802709 NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221
JBrowse link
G Ranbp2 RAN binding protein 2 ISO RGD PMID:17069463 RGD:9835347 NCBI chrNW_004955470:12,180,426...12,247,737
Ensembl chrNW_004955470:12,180,544...12,249,555
JBrowse link
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO OMIM NCBI chrNW_004955435:22,804,484...22,820,807
Ensembl chrNW_004955435:22,804,484...22,821,482
JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO ClinVar Annotator: match by term: MITOCHONDRIAL HMG-CoA SYNTHASE DEFICIENCY ClinVar NCBI chrNW_004955435:22,757,473...22,803,123
Ensembl chrNW_004955435:22,757,454...22,803,123
JBrowse link
abdominal obesity-metabolic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15309680 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:23320128 RGD:7241841 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
JBrowse link
abdominal obesity-metabolic syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:increased oxidation:cardiac muscle cell RGD PMID:23997093 RGD:13782087 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Fadd Fas associated via death domain treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281
JBrowse link
G Fas Fas cell surface death receptor ISO RGD PMID:30172001 RGD:13792561 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Lpl lipoprotein lipase treatment ISO RGD PMID:26996629 RGD:13794382 NCBI chrNW_004955403:43,646,084...43,672,116
Ensembl chrNW_004955403:43,646,084...43,673,967
JBrowse link
G Mttp microsomal triglyceride transfer protein ISO OMIM NCBI chrNW_004955496:7,963,323...8,022,393
Ensembl chrNW_004955496:7,963,262...8,009,838
JBrowse link
G Tlr2 toll like receptor 2 susceptibility ISO RGD PMID:19841034 RGD:15090861 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
abdominal obesity-metabolic syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahdc1 AT-hook DNA binding motif containing 1 ISO ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 ClinVar PMID:25741868 NCBI chrNW_004955452:6,767,250...6,832,989
Ensembl chrNW_004955452:6,767,266...6,832,868
JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B ISO OMIM NCBI chrNW_004955578:1,187,128...1,195,574
Ensembl chrNW_004955578:1,187,742...1,195,574
JBrowse link
adrenocorticotropic hormone deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe65 retinoid isomerohydrolase RPE65 ISO ClinVar Annotator: match by term: Adrenocorticotropic hormone deficiency ClinVar PMID:9326941 PMID:9501220 PMID:9843205 PMID:18632300 PMID:25741868 More... NCBI chrNW_004955423:23,184,326...23,208,206
Ensembl chrNW_004955423:23,183,937...23,208,282
JBrowse link
G Tbx19 T-box transcription factor 19 ISO OMIM NCBI chrNW_004955462:8,830,280...8,856,721
Ensembl chrNW_004955462:8,830,280...8,856,721
JBrowse link
autosomal dominant Wolfram syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wfs1 wolframin ER transmembrane glycoprotein ISO OMIM NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610
JBrowse link
background diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase ISO associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO protein:decreased expression:aqueous humor: RGD PMID:23853629 RGD:10402120 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G LOC102021956 alpha-2-macroglobulin treatment ISO RGD PMID:10848441 RGD:10046010 NCBI chrNW_004955413:6,019,457...6,062,366
Ensembl chrNW_004955413:6,019,082...6,062,529
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein:decreased expression:vitreous: RGD PMID:19799585 RGD:10449447 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
carnitine palmitoyltransferase I deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpt1a carnitine palmitoyltransferase 1A ISO OMIM NCBI chrNW_004955422:17,105,887...17,159,696
Ensembl chrNW_004955422:17,109,256...17,159,838
JBrowse link
Carnitine Palmitoyltransferase II Deficiency, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpt2 carnitine palmitoyltransferase 2 ISO OMIM NCBI chrNW_004955464:5,942,986...5,970,325
Ensembl chrNW_004955464:5,942,986...5,970,345
JBrowse link
cataract 47 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc16a12 solute carrier family 16 member 12 ISO OMIM NCBI chrNW_004955425:3,474,814...3,560,138
Ensembl chrNW_004955425:3,509,142...3,560,138
JBrowse link
Childhood-Onset Spasticity with Hyperglycinemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx5 glutaredoxin 5 ISO OMIM NCBI chrNW_004955438:17,067,017...17,076,162
Ensembl chrNW_004955438:17,066,955...17,075,789
JBrowse link
chromosome 17q11.2 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf135 ring finger protein 135 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: VAN ASPEREN SYNDROME
ClinVar Annotator: match by term: Macrocephaly, macrosomia, facial dysmorphism syndrome
CTD
ClinVar
PMID:17632510 PMID:21681106 PMID:25741868 PMID:27535533 PMID:28135719 More... NCBI chrNW_004955481:7,111,760...7,122,800 JBrowse link
Cleft Palate, Proliferative Retinopathy, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrc32 leucine rich repeat containing 32 ISO OMIM NCBI chrNW_004955414:15,296,704...15,309,088
Ensembl chrNW_004955414:15,296,563...15,309,088
JBrowse link
Combined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 ISO OMIM NCBI chrNW_004955404:14,361,540...14,412,533
Ensembl chrNW_004955404:14,360,832...14,412,533
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 ISO ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus ClinVar PMID:2256350 PMID:22563501 PMID:24220513 PMID:32214227 PMID:33983693 NCBI chrNW_004955423:25,269,459...25,382,664
Ensembl chrNW_004955423:25,269,466...25,377,641
JBrowse link
Congenital Hyperinsulinism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO ClinVar Annotator: match by term: Familial hyperinsulinism
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy
ClinVar Annotator: match by term: familial hyperinsulinism
DNA:missense mutations, nonsense mutations, splice-site mutations:CDS:multiple
DNA:mutations:exon, intron:multiple
CTD Direct Evidence: marker/mechanism
DNA:deletion: :p.S1387del (human)
DNA:mutations:exon:multiple
DNA:missense mutations:exon:p.G1485E (c.4454G>A), p.D1506E (c.4518C>A), p.M1544K (c.4541T>A) (human)
RGD
ClinVar
CTD
PMID:7716548 PMID:8751851 PMID:8923011 PMID:9041101 PMID:9536098 More... RGD:11067821 RGD:11069847 RGD:11070657 RGD:12743628 RGD:12790587 RGD:12790596 RGD:12790723 RGD:704365 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
JBrowse link
G Gck glucokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15277402 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO DNA:missense mutations: : RGD PMID:9571255 RGD:1302513 NCBI chrNW_004955510:5,987,811...6,021,001 JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO DNA:deletion:cds (human) RGD PMID:14693719 RGD:2306664 NCBI chrNW_004955496:1,835,034...1,861,410
Ensembl chrNW_004955496:1,835,034...1,861,407
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO DNA:mutations: :
ClinVar Annotator: match by term: Familial hyperinsulinism
RGD
ClinVar
PMID:10227563 PMID:10447526 PMID:10768098 PMID:10983627 PMID:15281001 More... RGD:12904701 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 ISO DNA:deletion, insertion:exon
ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL
DNA:SNPs:exon:c.151G>T, c.1017G>T (human)
DNA:missense mutations, frameshift mutations:CDS:multiple
DNA:deletion, frameshift mutation, missense mutations:exon:multiple
DNA:missense mutation:exon:p.R34H (c.101G>A) (human)
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:9867219 PMID:11318841 PMID:11872696 PMID:12196481 PMID:12475776 More... RGD:11069847 RGD:12743624 RGD:12743643 RGD:12790587 RGD:12790723 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 ISO ClinVar Annotator: match by term: KCNT2-related condition ClinVar PMID:29069600 NCBI chrNW_004955406:33,080,570...33,441,342
Ensembl chrNW_004955406:33,076,426...33,441,793
JBrowse link
G Tbc1d4 TBC1 domain family member 4 ISO RGD PMID:19470471 RGD:7248544 NCBI chrNW_004955404:31,516,727...31,691,414
Ensembl chrNW_004955404:31,622,102...31,691,517
JBrowse link
G Ucp2 uncoupling protein 2 ISO ClinVar Annotator: match by term: Familial hyperinsulinism ClinVar PMID:25741868 NCBI chrNW_004955414:17,592,914...17,596,477
Ensembl chrNW_004955414:17,592,914...17,596,477
JBrowse link
Developmental Delay, Epilepsy, and Neonatal Diabetes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 ISO ClinVar Annotator: match by term: DEND syndrome ClinVar PMID:25741868 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717
JBrowse link
Diabetes Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chrNW_004955404:14,700,808...14,927,944
Ensembl chrNW_004955404:14,700,808...14,928,617
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:20479236 RGD:7241550 NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO RGD PMID:20479236 RGD:7241550 NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
JBrowse link
G Casp9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24252320 RGD:13782355 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO Associated with obesity RGD PMID:21282363 RGD:6906933 NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO protein: decreased expression: serum RGD PMID:18025762 RGD:7242563 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812
JBrowse link
G Glo1 glyoxalase I no_association ISO DNA:SNP: :419C>A (human) RGD PMID:21738003 RGD:7242569 NCBI chrNW_004955437:4,728,709...4,749,834
Ensembl chrNW_004955437:4,728,709...4,749,834
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Muc1 mucin 1, cell surface associated ISO associated with Diabetes Mellitus, Experimental RGD PMID:23977093 RGD:7349380 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Nr0b2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chrNW_004955452:6,251,047...6,253,541
Ensembl chrNW_004955452:6,250,889...6,254,541
JBrowse link
G Pln phospholamban ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:diaphragm RGD PMID:23443767 RGD:7327179 NCBI chrNW_004955436:1,439,098...1,447,070
Ensembl chrNW_004955436:1,439,098...1,447,070
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19003935 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21548839 RGD:6484542 NCBI chrNW_004955426:25,079,718...25,102,090
Ensembl chrNW_004955426:25,079,718...25,102,090
JBrowse link
G Slc10a2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chrNW_004955404:8,122,119...8,137,236
Ensembl chrNW_004955404:8,122,119...8,137,236
JBrowse link
G Slc51a solute carrier family 51 alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chrNW_004955420:12,452,562...12,463,369
Ensembl chrNW_004955420:12,453,554...12,463,150
JBrowse link
G Slc51b solute carrier family 51 beta subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chrNW_004955450:10,365,554...10,374,209
Ensembl chrNW_004955450:10,365,554...10,374,209
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18057998 RGD:6771339 NCBI chrNW_004955452:6,409,833...6,467,841
Ensembl chrNW_004955452:6,409,833...6,467,841
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
diabetes mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:9618169 PMID:9648840 PMID:10204114 PMID:14692646 PMID:14715863 More... NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO protein:increased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:8620937 RGD:2313188 NCBI chrNW_004955487:290,434...302,405
Ensembl chrNW_004955487:290,557...302,547
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18378355 NCBI chrNW_004955431:19,025,663...19,027,026 JBrowse link
G Ager advanced glycosylation end-product specific receptor susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:23396398 RGD:7243186 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22831748 PMID:25741868 PMID:26336158 PMID:28492532 NCBI chrNW_004955513:4,142,074...4,145,097
Ensembl chrNW_004955513:4,135,460...4,149,677
JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO mRNA:reduced expression:pancreatic islet (mouse) RGD PMID:11904435 RGD:2313440 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
JBrowse link
G Alms1 ALMS1 centrosome and basal body associated protein ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18154657 PMID:21157496 PMID:21943378 PMID:22876109 PMID:24033266 More... NCBI chrNW_004955424:12,130,496...12,258,684
Ensembl chrNW_004955424:12,130,607...12,258,522
JBrowse link
G Alpk1 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chrNW_004955457:14,325,278...14,444,368
Ensembl chrNW_004955457:14,325,281...14,379,937
JBrowse link
G Apob apolipoprotein B ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chrNW_004955469:3,437,422...3,478,408
Ensembl chrNW_004955469:3,436,450...3,478,424
JBrowse link
G Apoc2 apolipoprotein C2 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830
JBrowse link
G Apoc3 apolipoprotein C3 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Apoe apolipoprotein E treatment ISO RGD PMID:17192461 RGD:1601230 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Apoh apolipoprotein H ISO protein:increased expression:plasma
mRNA:increased expression:retina
RGD PMID:9377806 PMID:18695102 RGD:2313982 RGD:2313991 NCBI chrNW_004955478:5,612,258...5,626,061
Ensembl chrNW_004955478:5,610,164...5,626,020
JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO protein:altered localization:retina RGD PMID:19748503 RGD:2316076 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
G Aqp4 aquaporin 4 ISO RGD PMID:19748503 RGD:2316076 NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
JBrowse link
G Arpc3 actin related protein 2/3 complex subunit 3 ISO associated with Obesity, Morbid;mRNA:decreased expression:omentum, adipose tissue (human) RGD PMID:26504501 RGD:11049459 NCBI chrNW_004955482:7,350,456...7,364,266
Ensembl chrNW_004955482:7,350,456...7,364,266
JBrowse link
G Asip agouti signaling protein ISO associated with Obesity;DNA:mutation (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:1473152 PMID:10426381 RGD:2314006 NCBI chrNW_004955422:27,021,810...27,150,339
Ensembl chrNW_004955422:27,020,386...27,057,626
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:19667185 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chrNW_004955403:52,825,397...52,874,007
Ensembl chrNW_004955403:52,832,604...52,874,264
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:23430896 PMID:23963299 PMID:25588603 PMID:25741868 PMID:26467025 More... NCBI chrNW_004955599:505,725...514,225
Ensembl chrNW_004955599:507,501...514,151
JBrowse link
G Casp3 caspase 3 ISO protein:increased expression:ovary RGD PMID:28412870 RGD:40400904 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11117918 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Cav1 caveolin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Cavin1 caveolae associated protein 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955451:16,364,915...16,374,523
Ensembl chrNW_004955451:16,364,915...16,374,634
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:serum RGD PMID:18385799 RGD:2307062 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Cd36 CD36 molecule ISO protein:increased expression:macrophage RGD PMID:17551591 RGD:2307209 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Cd40lg CD40 ligand ISO associated with Coronary Arteriosclerosis, Myocardial Infarction; protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1 like 1 ISO DNA:snp: :rs10946398(human) RGD PMID:19741467 RGD:2313940 NCBI chrNW_004955483:5,398,748...5,993,071
Ensembl chrNW_004955483:5,398,687...5,993,079
JBrowse link
G Cel carboxyl ester lipase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955513:2,324,025...2,382,877 JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12572680 NCBI chrNW_004955448:470,063...522,909
Ensembl chrNW_004955448:473,179...523,100
JBrowse link
G Cpb2 carboxypeptidase B2 ISO protein:increased expression, increased activity:plasma RGD PMID:14983223 RGD:2313643 NCBI chrNW_004955518:3,740,348...3,803,540
Ensembl chrNW_004955518:3,740,348...3,803,539
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233164 NCBI chrNW_004955422:17,105,887...17,159,696
Ensembl chrNW_004955422:17,109,256...17,159,838
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO associated with hepatocellular��carcinoma;DNA:hypermethylation:promoter (human) RGD PMID:32724427 RGD:150524282 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
JBrowse link
G Ctsb cathepsin B onset ISO DNA:transversion:cds:p.L26V (human) RGD PMID:18706099 RGD:2315528 NCBI chrNW_004955403:53,086,236...53,100,217
Ensembl chrNW_004955403:53,085,574...53,093,809
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23307960 RGD:9491759 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230
JBrowse link
G Dicer1 dicer 1, ribonuclease III ISO RGD PMID:22216196 RGD:149735536 NCBI chrNW_004955438:17,374,899...17,431,599
Ensembl chrNW_004955438:17,382,493...17,431,797
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955424:210,867...279,267
Ensembl chrNW_004955424:226,038...280,593
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression:plasma
protein:decreased expression:urine
RGD PMID:8914465 PMID:9212353 RGD:11060253 RGD:2313869 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159
JBrowse link
G F7 coagulation factor VII no_association ISO protein:increased activity:plasma (rat) RGD PMID:10899350 PMID:10910004 PMID:15258325 RGD:1598920 RGD:2312391 RGD:2312393 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11213886 PMID:20551625 RGD:7206845 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Foxp3 forkhead box P3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO protein:decreased activity:blood platelets RGD PMID:3609421 RGD:2315945 NCBI chrNW_004955452:3,744,071...3,759,776
Ensembl chrNW_004955452:3,744,755...3,759,676
JBrowse link
G Fxn frataxin ISO DNA:deletion:exon (mouse) RGD PMID:12925693 RGD:2307048 NCBI chrNW_004955434:3,983,225...4,008,324
Ensembl chrNW_004955434:3,980,653...4,008,761
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO protein:decreased activity:blood RGD PMID:24865682 RGD:10449112 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Gad1 glutamate decarboxylase 1 ISO RGD PMID:1924335 RGD:728511 NCBI chrNW_004955449:3,964,006...4,001,850
Ensembl chrNW_004955449:3,963,705...4,001,850
JBrowse link
G Gc GC vitamin D binding protein ISO protein:increased expression:ascitic fluid RGD PMID:20054029 RGD:5509921 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491
JBrowse link
G Gck glucokinase ISO neonatal-onset diabetes mellitus,OMIM:606176;DNA:point mutation:exon:T228M
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
RGD
ClinVar
PMID:7542040 PMID:8325892 PMID:8433729 PMID:8446612 PMID:8454109 More... RGD:1601295 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Cystic Fibrosis; protein:increased activity:plasma RGD PMID:17888134 RGD:2315601 NCBI chrNW_004955455:8,082,578...8,099,523 JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO human gene, mouse model RGD PMID:15582721 RGD:2312617 NCBI chrNW_004955574:140,307...153,684
Ensembl chrNW_004955574:140,307...156,899
JBrowse link
G Glis3 GLIS family zinc finger 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955434:8,140,965...8,581,889
Ensembl chrNW_004955434:8,145,053...8,573,537
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955510:5,987,811...6,021,001 JBrowse link
G Gnb3 G protein subunit beta 3 no_association ISO DNA:polymorphism: :multiple (human) RGD PMID:16908025 RGD:2313206 NCBI chrNW_004955413:4,440,693...4,447,419
Ensembl chrNW_004955413:4,440,693...4,447,416
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:skeletal muscle (mouse) RGD PMID:18562625 PMID:18936159 RGD:2312632 RGD:2312633 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032
JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:decreased activity:blood: RGD PMID:22540111 RGD:7257584 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22662265 PMID:25741868 PMID:27104957 PMID:28492532 NCBI chrNW_004955496:1,835,034...1,861,410
Ensembl chrNW_004955496:1,835,034...1,861,407
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hgf hepatocyte growth factor ISO mRNA, protein:increased expression:cornea RGD PMID:16186340 RGD:2313569 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:15476492 RGD:2313755 NCBI chrNW_004955425:25,362,165...25,380,611
Ensembl chrNW_004955425:25,359,884...25,380,745
JBrowse link
G Hnf1a HNF1 homeobox A ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:8945470 PMID:9032114 PMID:9112026 PMID:9133564 PMID:9166684 More... NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613
JBrowse link
G Hnf1b HNF1 homeobox B ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15930087 PMID:16249435 PMID:18065799 PMID:19639018 PMID:20633866 More... NCBI chrNW_004955451:320,283...371,420
Ensembl chrNW_004955451:320,283...371,420
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:10983627 PMID:16946562 PMID:18414213 PMID:24033266 PMID:25741868 More... NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G Ica1 islet cell autoantigen 1 ISO RGD PMID:7918678 RGD:633043 NCBI chrNW_004955432:15,136,606...15,297,415
Ensembl chrNW_004955432:15,136,757...15,269,125
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:19394054 RGD:2313467 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Igf1 insulin like growth factor 1 ISO mRNA,protein:decreased expression:corpus cavernosum: RGD PMID:22133301 RGD:10046054 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:16642022 RGD:2311506 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:22802947 RGD:7364853 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:18503494 RGD:2311530 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913
JBrowse link
G Il33 interleukin 33 ISO protein:increased expression:serum,ovary RGD PMID:28412870 RGD:40400904 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il6 interleukin 6 susceptibility ISO protein:increased expression:extracellular space (human)
associated with Dementia; protein:increased expression:brain (human)
mRNA:decreased expression:dendritic cell (mouse)
DNA:polymorphism:promoter:-174G>C (human)
RGD PMID:18689695 PMID:19120268 PMID:19139294 PMID:19442860 RGD:2307180 RGD:2307273 RGD:2307278 RGD:2307293 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ins insulin ISO protein:altered localization :endoplasmic reticulum
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
CTD Direct Evidence: marker/mechanism
DNA, protein:missense mutations, altered processing:exons, endoplasmic reticulum:multiple
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:point mutation (mouse)
DNA, protein:missense mutations:exons:multiple
RGD
ClinVar
CTD
PMID:2055425 PMID:7294224 PMID:7624867 PMID:8400068 PMID:11446671 More... RGD:2311109 RGD:2311115 RGD:2317259 RGD:2317260 RGD:2317262 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Insr insulin receptor ISO DNA:deletions, missense mutation:multiple (human)
ClinVar Annotator: match by term: Monogenic diabetes
RGD
ClinVar
PMID:2040394 PMID:2211730 PMID:2983222 PMID:8257688 PMID:8432414 More... RGD:2307343 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
JBrowse link
G Irs1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10591678 NCBI chrNW_004955453:7,685,715...7,742,262
Ensembl chrNW_004955453:7,685,715...7,742,262
JBrowse link
G Itga2 integrin subunit alpha 2 ISO protein:increased expression:monocyte (human) RGD PMID:17466965 RGD:2307424 NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170
JBrowse link
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 ISO Diabetes Mellitus, permanent neonatal, OMIM:606176
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
DNA:mutation: :p.V59M (mouse)
RGD
ClinVar
PMID:8897013 PMID:10338089 PMID:12524280 PMID:14715863 PMID:15115830 More... RGD:1625256 RGD:2311536 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717
JBrowse link
G Kif1a kinesin family member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chrNW_004955542:756,834...832,805
Ensembl chrNW_004955542:756,835...832,889
JBrowse link
G Kif5b kinesin family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chrNW_004955429:23,632,246...23,678,797
Ensembl chrNW_004955429:23,631,282...23,678,562
JBrowse link
G Klf11 Kruppel like factor 11 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15774581 PMID:17130512 PMID:18414213 PMID:18593768 PMID:19122346 More... NCBI chrNW_004955487:5,448,869...5,454,322 JBrowse link
G Lep leptin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:15028607 PMID:25741868 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
JBrowse link
G Lmna lamin A/C ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2007407 PMID:2270059 PMID:2526018 PMID:10587585 PMID:10655060 More... NCBI chrNW_004955545:2,290,076...2,310,982
Ensembl chrNW_004955545:2,290,037...2,313,033
JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO associated with Smoking Inhalation Injury; DNA:polymorphism:3' UTR:5639T>C (human) RGD PMID:11996959 RGD:2307073 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
G LOC102012042 cytochrome b-245 heavy chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912
JBrowse link
G LOC102015388 cytochrome b5 reductase 4 ISO RGD PMID:15247412 RGD:2315644 NCBI chrNW_004955411:11,424,923...11,508,193
Ensembl chrNW_004955411:11,424,505...11,508,193
JBrowse link
G LOC102027002 lanosterol 14-alpha demethylase ISO mRNA,protein:decreased expression:liver RGD PMID:10876162 RGD:41412168 NCBI chrNW_004955432:9,092,923...9,112,615
Ensembl chrNW_004955432:9,092,933...9,112,615
JBrowse link
G Lrp1 LDL receptor related protein 1 treatment ISO RGD PMID:22889684 RGD:13800521 NCBI chrNW_004955458:4,861,431...4,941,939
Ensembl chrNW_004955458:4,861,431...4,941,146
JBrowse link
G Mafa MAF bZIP transcription factor A treatment ISO RGD PMID:23801580 RGD:13506744 NCBI chrNW_004955454:2,134,340...2,136,962
Ensembl chrNW_004955454:2,135,484...2,136,560
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16731828 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808
JBrowse link
G Marco macrophage receptor with collagenous structure ISO protein:decreased expression:Alveolar macrophage RGD PMID:27630197 RGD:41412199 NCBI chrNW_004955459:10,700,645...10,739,222
Ensembl chrNW_004955459:10,698,294...10,739,131
JBrowse link
G Mc4r melanocortin 4 receptor ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:9267995 PMID:10078568 PMID:10199800 PMID:10592235 PMID:10903341 More... NCBI chrNW_004955402:44,453,973...44,456,689
Ensembl chrNW_004955402:44,455,294...44,456,292
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO RGD PMID:11159210 RGD:8693313 NCBI chrNW_004955412:5,965,388...5,976,353
Ensembl chrNW_004955412:5,965,394...5,976,382
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association ISO DNA:transition:cds:g.677C>T (human) RGD PMID:9607212 RGD:38501049 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chrNW_004955456:13,353,780...13,363,956
Ensembl chrNW_004955456:13,354,011...13,363,891
JBrowse link
G Neurod1 neuronal differentiation 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955403:15,595,888...15,600,040
Ensembl chrNW_004955403:15,595,888...15,600,040
JBrowse link
G Nppb natriuretic peptide B onset ISO RGD PMID:23733199 RGD:7246907 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Nr0b2 nuclear receptor subfamily 0 group B member 2 ISO mRNA:increased expression:pancreatic islet RGD PMID:17259388 RGD:2311606 NCBI chrNW_004955452:6,251,047...6,253,541
Ensembl chrNW_004955452:6,250,889...6,254,541
JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chrNW_004955427:19,459,936...19,487,276
Ensembl chrNW_004955427:19,459,936...19,487,276
JBrowse link
G Nr1i3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chrNW_004955468:12,985,105...13,002,850 JBrowse link
G Pax4 paired box 4 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955479:8,660,089...8,664,463
Ensembl chrNW_004955479:8,660,089...8,664,463
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO mRNA, decreased expression:pancreatic islet (mouse)
ClinVar Annotator: match by term: Monogenic diabetes
RGD
ClinVar
PMID:10545530 PMID:10545531 PMID:10720084 PMID:11022198 PMID:11270685 More... RGD:2308812 NCBI chrNW_004955497:7,281,886...7,307,969 JBrowse link
G Plin1 perilipin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955416:15,538,309...15,549,275
Ensembl chrNW_004955416:15,533,268...15,549,772
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19153526 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16229851 PMID:19022366 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:16168052 PMID:19748282 PMID:25741868 PMID:27749844 PMID:28492532 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
G Ppp1r3a protein phosphatase 1 regulatory subunit 3A ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:12118251 PMID:25741868 PMID:28492532 NCBI chrNW_004955432:19,854,649...19,893,148
Ensembl chrNW_004955432:19,858,423...19,893,175
JBrowse link
G Prom1 prominin 1 ISO RGD PMID:11237753 RGD:68837 NCBI chrNW_004955480:7,955,501...8,059,537
Ensembl chrNW_004955480:7,961,389...8,059,589
JBrowse link
G Pten phosphatase and tensin homolog ISO protein:increased expression, increased phosphorylation:inferior vena cava RGD PMID:16961925 RGD:2292543 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:25775927 PMID:28492532 NCBI chrNW_004955429:5,807,804...5,809,522
Ensembl chrNW_004955429:5,808,124...5,809,522
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:15885672 RGD:5143927 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp: cds: C1858T RGD PMID:18764813 RGD:6484729 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351
JBrowse link
G Rfx6 regulatory factor X6 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15592663 PMID:18414213 PMID:20148032 PMID:25741868 PMID:28492532 More... NCBI chrNW_004955436:213,810...278,699
Ensembl chrNW_004955436:213,809...280,577
JBrowse link
G Serpina7 serpin family A member 7 ISO RGD PMID:8742570 RGD:2312329 NCBI chrNW_004955548:2,855,377...2,861,946
Ensembl chrNW_004955548:2,855,111...2,861,952
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO RGD PMID:10910004 RGD:2312393 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Shbg sex hormone binding globulin ISO protein:increased expression:plasma RGD PMID:18346991 RGD:2313784 NCBI chrNW_004955467:9,301,173...9,305,010 JBrowse link
G Shld2 shieldin complex subunit 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004955510:6,021,477...6,114,745
Ensembl chrNW_004955510:6,075,510...6,114,898
JBrowse link
G Sim1 SIM bHLH transcription factor 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2152513 PMID:16924270 PMID:21512513 PMID:23778136 PMID:23778139 More... NCBI chrNW_004955411:26,173,009...26,256,545
Ensembl chrNW_004955411:26,173,009...26,259,752
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894401 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link
G Slc19a2 solute carrier family 19 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes RGD
ClinVar
PMID:10391221 PMID:25741868 PMID:28492532 RGD:1599325 NCBI chrNW_004955462:7,786,920...7,804,828
Ensembl chrNW_004955462:7,786,913...7,805,792
JBrowse link
G Slc22a12 solute carrier family 22 member 12 ISO protein:decreased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chrNW_004955422:20,555,458...20,561,818
Ensembl chrNW_004955422:20,556,098...20,596,012
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO RGD PMID:10022440 RGD:12879500 NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:8027028 PMID:8063045 PMID:11810292 PMID:23986439 PMID:25741868 More... NCBI chrNW_004955420:1,101,769...1,129,672
Ensembl chrNW_004955420:1,101,769...1,129,715
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ameliorates ISO RGD PMID:15100317 RGD:151232286 NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23786522 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:12830380 RGD:1581299 NCBI chrNW_004955480:257,716...263,149 JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:10835640 PMID:15980664 PMID:16849362 PMID:18978175 PMID:23017645 More... NCBI chrNW_004955415:6,328,672...6,378,611
Ensembl chrNW_004955415:6,371,059...6,378,529
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO RGD PMID:12749121 RGD:1600067 NCBI chrNW_004955441:12,149...95,733
Ensembl chrNW_004955441:10,443...95,743
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO associated with Cystic Fibrosis;DNA:SNP (human) RGD PMID:19585101 RGD:2312417 NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO protein:increased expression:plasma: RGD PMID:8914465 RGD:11060253 NCBI chrNW_004955403:10,925,155...11,004,229
Ensembl chrNW_004955403:10,924,893...11,004,284
JBrowse link
G Thbs2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chrNW_004955411:4,315,055...4,347,044
Ensembl chrNW_004955411:4,314,984...4,347,383
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO protein:decreased expression:glomerulus RGD PMID:19506087 RGD:2312464 NCBI chrNW_004955516:507,113...511,360
Ensembl chrNW_004955516:505,789...512,118
JBrowse link
G Tlr4 toll like receptor 4 ISO protein:increased expression:monocyte RGD PMID:15632890 PMID:19210958 RGD:1580736 RGD:2312485 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 ISO RGD PMID:10192335 RGD:2312735 NCBI chrNW_004955486:1,839,642...1,910,080 JBrowse link
G Ucp3 uncoupling protein 3 ISO RGD PMID:17587402 RGD:2313514 NCBI chrNW_004955414:17,558,889...17,578,108
Ensembl chrNW_004955414:17,558,889...17,578,737
JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs: :rs731236, rs1544410, rs7975232 (human) RGD PMID:22856230 RGD:8158070 NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048
JBrowse link
G Vwf von Willebrand factor treatment ISO RGD PMID:19722571 RGD:7207029 NCBI chrNW_004955413:3,672,470...3,825,588
Ensembl chrNW_004955413:3,672,470...3,819,571
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein onset ISO DNA:missense mutations:cds:p.R456H, p.R611H (rs1801206, rs1801214) (human)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
RGD
ClinVar
PMID:10521293 PMID:10624825 PMID:10679252 PMID:11161832 PMID:11244483 More... RGD:149735331 RGD:8694404 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610
JBrowse link
G Zfp57 ZFP57 zinc finger protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:18414213 PMID:18622393 PMID:23748067 PMID:25741868 PMID:28492532 NCBI chrNW_004955583:151,338...154,827 JBrowse link
Diabetes Mellitus, Congenital Autoimmune term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12930356 NCBI chrNW_004955419:12,763,343...12,790,044
Ensembl chrNW_004955419:12,762,748...12,788,117
JBrowse link
Diabetes Mellitus, New-Onset after Transplantation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:22645144 RGD:10040997 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
diabetic angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy3 adenylate cyclase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955469:6,933,208...7,026,179
Ensembl chrNW_004955469:6,929,092...7,026,758
JBrowse link
G Adcy8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955461:5,497,708...5,725,574
Ensembl chrNW_004955461:5,497,628...5,725,574
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372816 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19733855 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Ass1 argininosuccinate synthase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25033204 NCBI chrNW_004955513:443,372...485,190
Ensembl chrNW_004955513:445,462...485,190
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:15878326 RGD:7241570 NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Cd28 CD28 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased expression:T cell RGD PMID:15504310 RGD:2307197 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:14963650 RGD:2314223 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955462:2,491,504...2,547,587
Ensembl chrNW_004955462:2,491,504...2,536,385
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 susceptibility ISO associated with Diabetic Foot;DNA:polymorphism:3' utr (human) RGD PMID:16723689 RGD:2306558 NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690
JBrowse link
G Epo erythropoietin ISO OMIM NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression:plasma
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD PMID:9285207 PMID:16371118 RGD:2313861 RGD:2313868 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159
JBrowse link
G Fas Fas cell surface death receptor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15803113 RGD:2315753 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD
RGD
PMID:15803113 PMID:25381014 RGD:2315753 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:12716757 RGD:1601179 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:21411989 RGD:7242686 NCBI chrNW_004955467:10,333,537...10,347,488
Ensembl chrNW_004955467:10,333,575...10,346,989
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
G Hfe homeostatic iron regulator ISO OMIM NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16959961 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta
RGD PMID:18093596 PMID:18796303 RGD:2306988 RGD:2313473 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Igfbp1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chrNW_004955456:6,810,461...6,814,944
Ensembl chrNW_004955456:6,810,056...6,815,685
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO OMIM NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO RGD PMID:12477149 RGD:1582581 NCBI chrNW_004955409:37,438,924...37,448,704
Ensembl chrNW_004955409:37,440,541...37,448,437
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16681562 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea RGD PMID:19241604 PMID:19587355 RGD:2313210 RGD:4891384 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12124201 PMID:19241604 PMID:29329611 RGD:13504708 RGD:4891384 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased tyrosine phosphorylation:conceptus RGD PMID:10329590 RGD:2311657 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
JBrowse link
G Plat plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:18945481 RGD:2311663 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
JBrowse link
G Polr1c RNA polymerase I and III subunit C ISO ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar PMID:11978667 NCBI chrNW_004955437:9,346,397...9,350,591
Ensembl chrNW_004955437:9,346,397...9,350,591
JBrowse link
G Pon1 paraoxonase 1 ISO OMIM NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21926342 RGD:10041069 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:deletion, haplotype:promoter:g.-676_-674delG (human) RGD PMID:9844142 RGD:8547700 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Serpinf1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955481:1,414,930...1,426,436
Ensembl chrNW_004955481:1,414,930...1,426,241
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 ISO OMIM NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:mesentery, blood vessel RGD PMID:10625572 RGD:2300063 NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Thbs2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chrNW_004955411:4,315,055...4,347,044
Ensembl chrNW_004955411:4,314,984...4,347,383
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:c.-308G>A (human) RGD PMID:18575614 RGD:2313255 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Vegfa vascular endothelial growth factor A ISO OMIM NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
Diabetic Cardiomyopathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adipor1 adiponectin receptor 1 ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chrNW_004955406:38,939,167...38,955,647
Ensembl chrNW_004955406:38,936,588...38,955,352
JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental;
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:heart (rat)
RGD PMID:23251674 RGD:7244283 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29353218 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15587404 PMID:16025228 NCBI chrNW_004955534:3,653,112...3,654,248
Ensembl chrNW_004955534:3,653,157...3,654,248
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:18332268 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:16685413 PMID:21441944 RGD:6771209 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754
JBrowse link
G Atp7a ATPase copper transporting alpha treatment ISO RGD PMID:24927960 RGD:11341676 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21296063 RGD:10053697 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:myocardium (mouse)
RGD PMID:21296063 PMID:21474815 RGD:10053697 RGD:11522727 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp8 caspase 8 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Casq2 calsequestrin 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21441944 RGD:6771209 NCBI chrNW_004955435:18,941,975...18,996,027
Ensembl chrNW_004955435:18,941,936...18,996,200
JBrowse link
G Casr calcium sensing receptor ISO protein:decreased expression:myocardium (rat) RGD PMID:22137362 RGD:7205677 NCBI chrNW_004955427:21,486,608...21,574,017
Ensembl chrNW_004955427:21,486,427...21,575,210
JBrowse link
G Cfl1 cofilin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:27576917 RGD:11568692 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
JBrowse link
G Ctnnb1 catenin beta 1 ISO mRNA,protein:increased expression:heart RGD PMID:25586361 RGD:13524855 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chrNW_004955457:3,177,905...4,236,152
Ensembl chrNW_004955457:3,177,991...4,228,558
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23453443 PMID:23853776 RGD:10412713 RGD:9586347 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11375343 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:23843977 RGD:7247697 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Ins insulin ISO CTD Direct Evidence: therapeutic CTD PMID:20828608 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16129698 NCBI chrNW_004955559:457,030...461,086
Ensembl chrNW_004955559:456,932...465,704
JBrowse link
G LOC102021956 alpha-2-macroglobulin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21742475 RGD:10046044 NCBI chrNW_004955413:6,019,457...6,062,366
Ensembl chrNW_004955413:6,019,082...6,062,529
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152
JBrowse link
G Mylk2 myosin light chain kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:9005973 RGD:1580244 NCBI chrNW_004955422:29,141,699...29,154,927
Ensembl chrNW_004955422:29,141,348...29,154,927
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23353773 PMID:23453443 RGD:10412713 RGD:10412721 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29274332 RGD:13504685 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Nppa natriuretic peptide A treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23497378 RGD:7297056 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003
JBrowse link
G Nrg1 neuregulin 1 ISO associated with Diabetes Mellitus, Experimental;protein:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chrNW_004955463:8,009,436...9,037,116
Ensembl chrNW_004955463:8,009,530...9,037,116
JBrowse link
G Pln phospholamban ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:heart left ventricle RGD PMID:22185592 RGD:7327207 NCBI chrNW_004955436:1,439,098...1,447,070
Ensembl chrNW_004955436:1,439,098...1,447,070
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO Strain: ZDF RGD PMID:19317897 RGD:5509944 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685413 NCBI chrNW_004955492:2,647,597...3,275,512
Ensembl chrNW_004955492:2,648,956...3,076,509
JBrowse link
G Slc25a4 solute carrier family 25 member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:18945756 NCBI chrNW_004955403:23,878,329...23,882,322
Ensembl chrNW_004955403:23,878,329...23,882,322
JBrowse link
G Slc8a1 solute carrier family 8 member A1 treatment ISO RGD PMID:27058979 RGD:13628396 NCBI chrNW_004955441:7,653,107...8,037,784
Ensembl chrNW_004955441:7,656,031...7,957,640
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16980342 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
JBrowse link
G Tert telomerase reverse transcriptase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21264070 RGD:11038677 NCBI chrNW_004955504:649,248...669,796
Ensembl chrNW_004955504:651,779...670,589
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909696 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
diabetic cataract term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsr glutathione-disulfide reductase ISO RGD PMID:12518238 RGD:10401829 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
Diabetic Cystopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nuclei: RGD PMID:20879002 RGD:10053565 NCBI chrNW_004955473:4,891,955...4,925,705
Ensembl chrNW_004955473:4,891,955...4,926,428
JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23129268 RGD:10053664 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
JBrowse link
Diabetic Embryopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO RGD PMID:26419589 RGD:13792560 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281
JBrowse link
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23529380 PMID:24291733 RGD:7244255 RGD:8553040 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G App amyloid beta precursor protein treatment ISO associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137
JBrowse link
G Ide insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chrNW_004955425:819,461...926,440
Ensembl chrNW_004955425:847,615...926,318
JBrowse link
G Ngf nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
JBrowse link
G Ngfr nerve growth factor receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
Diabetic Foot term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:plasma RGD PMID:20836881 RGD:5686889 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO associated with Diabetes Mellitus, Type 2;protein:decreased expression:blood RGD PMID:21941211 RGD:6767555 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Gja1 gap junction protein alpha 1 ISO protein:increased expression:dermis RGD PMID:22455314 RGD:7207269 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
JBrowse link
G Igf1 insulin like growth factor 1 ISO protein:decreased expression:fibroblast of dermis,stratum basale of epidermis: RGD PMID:10727985 RGD:8549356 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il15 interleukin 15 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:dermis, endothelial cell RGD PMID:17014667 RGD:2313575 NCBI chrNW_004955471:1,496,352...1,583,919
Ensembl chrNW_004955471:1,497,483...1,511,469
JBrowse link
G Mbl2 mannose binding lectin 2 ISO protein:increased expression:serum: RGD PMID:19997692 RGD:8694068 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
JBrowse link
G Mmp9 matrix metallopeptidase 9 severity ISO RGD PMID:22688339 RGD:8547813 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Plat plasminogen activator, tissue type ISO RGD PMID:17275886 RGD:2311669 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
JBrowse link
G Ptx3 pentraxin 3 ISO protein:decreased expression:plasma (human) RGD PMID:30767386 RGD:38501100 NCBI chrNW_004955448:8,366,795...8,373,010
Ensembl chrNW_004955448:8,366,925...8,372,411
JBrowse link
G Tlr4 toll like receptor 4 susceptibility ISO DNA:SNPs,haplotype: :rs4986790,rs4986791,rs10759931,rs1927911(human); RGD PMID:23936790 RGD:7777174 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
diabetic ketoacidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 ISO RGD PMID:12021537 RGD:2314345 NCBI chrNW_004955547:547,770...555,764
Ensembl chrNW_004955547:547,064...555,958
JBrowse link
G Ins insulin ISO CTD Direct Evidence: therapeutic CTD PMID:11430560 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Insr insulin receptor ISO RGD PMID:15254588 RGD:1302526 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
JBrowse link
G Pax4 paired box 4 susceptibility ISO ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone, susceptibility to OMIM
ClinVar
PMID:15509590 PMID:18414213 PMID:25741868 PMID:28492532 NCBI chrNW_004955479:8,660,089...8,664,463
Ensembl chrNW_004955479:8,660,089...8,664,463
JBrowse link
G Serpina7 serpin family A member 7 ISO protein:decreased expression:serum RGD PMID:6768790 RGD:2312332 NCBI chrNW_004955548:2,855,377...2,861,946
Ensembl chrNW_004955548:2,855,111...2,861,952
JBrowse link
Diabetic Nephropathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 no_association ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple (human)
mRNA, protein:altered expression:kidney
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:decreased expression:kidney
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:12623933 PMID:17600118 PMID:18235039 PMID:19034303 PMID:19077419 More... RGD:2313796 RGD:2313797 RGD:2313800 NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495
JBrowse link
G Acvr1 activin A receptor type 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:11675415 RGD:2313802 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression
no_association
ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs2241766 (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1501299 (human)
RGD
CTD
PMID:17942768 PMID:17970779 PMID:21945031 PMID:23260797 RGD:5686409 RGD:8694443 RGD:8694475 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adora1 adenosine A1 receptor ISO associated with Diabetes Mellitus, Experimental RGD PMID:19552053 RGD:2313803 NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism (human) RGD PMID:15660746 RGD:2313545 NCBI chrNW_004955470:3,711,075...3,714,450
Ensembl chrNW_004955470:3,711,031...3,714,241
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9867224 RGD:5684403 NCBI chrNW_004955463:13,663,064...13,665,553 JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment
susceptibility
ISO associated with Diabetes Mellitus, Type 2; protein:increased expression:renal cortex (mouse)
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney cortex, glomerulus
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1704G>T (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus;DNA:polymorphisms, haplotype:cds, intron:p.G82S, g.2184A>G (rs2070600, rs3134940) (human)
RGD PMID:12651605 PMID:14747204 PMID:19142024 PMID:21533139 PMID:21856399 More... RGD:2325651 RGD:7243248 RGD:7243852 RGD:7244174 RGD:7244187 RGD:8695982 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Agt angiotensinogen no_association
disease_progression
ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :p.M235T (human)
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)
RGD
CTD
PMID:8772723 PMID:10862638 PMID:11938025 PMID:17890855 PMID:19014923 More... RGD:11039058 RGD:8548868 RGD:8548872 RGD:8548885 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1166A>C (human)
RGD PMID:12172324 PMID:12476891 RGD:6903861 RGD:8548891 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255
JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:18565281 RGD:6903847 NCBI chrNW_004955534:3,653,112...3,654,248
Ensembl chrNW_004955534:3,653,157...3,654,248
JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15698447 RGD:2313813 NCBI chrNW_004955420:21,071,111...21,078,397
Ensembl chrNW_004955420:21,069,681...21,078,298
JBrowse link
G Alb albumin ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
associated with Metabolic Syndrome X;protein:increased expression:urine
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16380483 PMID:19246226 PMID:19397971 PMID:19424163 PMID:21441310 RGD:2306882 RGD:2306885 RGD:2306886 RGD:5135032 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Alpk1 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chrNW_004955457:14,325,278...14,444,368
Ensembl chrNW_004955457:14,325,281...14,379,937
JBrowse link
G Apoa1 apolipoprotein A1 ISO RGD PMID:9829487 RGD:2313960 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298
JBrowse link
G Apoa2 apolipoprotein A2 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:9829487 PMID:11126402 RGD:2313958 RGD:2313960 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apob apolipoprotein B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19324028 RGD:2313979 NCBI chrNW_004955469:3,437,422...3,478,408
Ensembl chrNW_004955469:3,436,450...3,478,424
JBrowse link
G Apoc1 apolipoprotein C1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:very-low-density lipoprotein particle RGD PMID:12753304 RGD:2313950 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc3 apolipoprotein C3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-455T>C RGD PMID:16813599 RGD:2306755 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Apoe apolipoprotein E susceptibility
no_association
ISO DNA:missense mutations, haplotype:cds:p.C112R, p.R158C (human)
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, type 1;
RGD PMID:11495633 PMID:21127830 PMID:22859852 RGD:6902935 RGD:6903840 RGD:7771553 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Apoh apolipoprotein H ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:11302005 RGD:2313989 NCBI chrNW_004955478:5,612,258...5,626,061
Ensembl chrNW_004955478:5,610,164...5,626,020
JBrowse link
G Aqp2 aquaporin 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased secretion:urine RGD PMID:12218327 RGD:2314343 NCBI chrNW_004955547:547,770...555,764
Ensembl chrNW_004955547:547,064...555,958
JBrowse link
G Arg2 arginase 2 ISO RGD PMID:21926276 RGD:6902923 NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta treatment ISO mRNA:decreased expression:renal glomerulus (rat) RGD PMID:22591908 RGD:13792578 NCBI chrNW_004955458:4,188,167...4,195,575
Ensembl chrNW_004955458:4,186,461...4,195,494
JBrowse link
G Axl AXL receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 NCBI chrNW_004955555:189,445...218,509
Ensembl chrNW_004955555:189,174...218,565
JBrowse link
G Azin1 antizyme inhibitor 1 treatment ISO RGD PMID:26751697 RGD:14700801 NCBI chrNW_004955417:27,231,695...27,259,564
Ensembl chrNW_004955417:27,231,696...27,259,564
JBrowse link
G Bdkrb2 bradykinin receptor B2 susceptibility ISO associated with Diabetes Mellitus, Experimental RGD PMID:17596525 RGD:2313335 NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
JBrowse link
G Bdnf brain derived neurotrophic factor ISO RGD PMID:20557422 RGD:4891134 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Becn1 beclin 1 ISO protein:increased expression:kidney RGD PMID:21866636 RGD:6483069 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO associated with Diabetes Mellitus, Type2; protein:increased expression:serum: RGD PMID:9347246 RGD:7207424 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO RGD PMID:17437042 RGD:2289036 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795
JBrowse link
G C3 complement C3 ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Type 1; protein:increased expression:kidney:
RGD PMID:19200691 PMID:25662584 RGD:11040807 RGD:7183082 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B treatment ISO RGD PMID:27273361 RGD:13506726 NCBI chrNW_004955513:5,654,915...5,823,094
Ensembl chrNW_004955513:5,654,238...5,824,386
JBrowse link
G Capn10 calpain 10 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22012129 RGD:7247733 NCBI chrNW_004955542:874,083...885,085
Ensembl chrNW_004955542:874,083...885,084
JBrowse link
G Casp3 caspase 3 treatment ISO associated with Diabetes Mellitus, Experimental;protein:increased activity:kidney
associated with Diabetes Mellitus, Experimental
associated with type 2 diabetes mellitus
RGD PMID:19601660 PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 RGD:2311440 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp7 caspase 7 treatment ISO associated with type 2 diabetes mellitus RGD PMID:28456626 RGD:13782304 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524
JBrowse link
G Casp8 caspase 8 treatment ISO associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
JBrowse link
G Casp9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29606028 PMID:30038056 RGD:13782342 RGD:13792586 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Cat catalase ISO associated with experimentally induced diabetes
rat gene in db/db mice
RGD PMID:20299359 PMID:21525431 PMID:21686137 PMID:22315314 RGD:7205651 RGD:7205662 RGD:7205665 RGD:7205676 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17664181 RGD:7483629 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-28C>G
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:urine
RGD PMID:12610055 PMID:18326229 RGD:2307063 RGD:2307107 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Ccn2 cellular communication network factor 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney, glomerulus (rat)
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)
RGD PMID:19065061 PMID:19895808 RGD:2314366 RGD:2314604 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480
JBrowse link
G Ccne1 cyclin E1 ISO protein:increased expression:kidney RGD PMID:17825795 RGD:2289273 NCBI chrNW_004955468:7,803,610...7,814,872
Ensembl chrNW_004955468:7,803,346...7,814,872
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 no_association ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.V64I (human)
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:11756347 PMID:17631861 RGD:2313558 RGD:2313563 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Cd36 CD36 molecule ISO protein:increased expression:renal proximal tubule, endothelial cell RGD PMID:15737001 RGD:2307215 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Cd38 CD38 molecule ISO associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:19073639 PMID:19300526 RGD:2307227 RGD:2307228 NCBI chrNW_004955480:8,177,178...8,218,483
Ensembl chrNW_004955480:8,178,473...8,217,643
JBrowse link
G Cd40lg CD40 ligand ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:serum RGD PMID:18756582 RGD:2314208 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27652271 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO mRNA, protein:increased expression:kidney, glomerulus RGD PMID:15698433 PMID:16805985 RGD:2293619 RGD:2293628 NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542
JBrowse link
G Cfl1 cofilin 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:renal glomerulus (rat) RGD PMID:24726496 RGD:11570419 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
JBrowse link
G Clu clusterin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:18949565 RGD:9068414 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
JBrowse link
G Cndp1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17942768 PMID:21393041 PMID:21573905 RGD:7207213 NCBI chrNW_004955402:57,970,205...58,019,980
Ensembl chrNW_004955402:57,970,161...58,019,479
JBrowse link
G Cndp2 carnosine dipeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21573905 NCBI chrNW_004955402:57,939,003...57,960,056
Ensembl chrNW_004955402:57,938,276...57,960,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus (rat) RGD PMID:22903132 RGD:8552684 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17582205 PMID:18682491 PMID:19466391 PMID:27997345 RGD:2311340 RGD:2311342 NCBI chrNW_004955404:2,196,193...2,327,324
Ensembl chrNW_004955404:2,260,029...2,326,074
JBrowse link
G Cpb2 carboxypeptidase B2 susceptibility ISO DNA:SNP:cds:1040C>T(human)
protein:increased expression:plasma
RGD PMID:12574207 PMID:22932273 RGD:7243116 RGD:7243123 NCBI chrNW_004955518:3,740,348...3,803,540
Ensembl chrNW_004955518:3,740,348...3,803,539
JBrowse link
G Creb1 cAMP responsive element binding protein 1 susceptibility ISO RGD PMID:15862029 RGD:10059365 NCBI chrNW_004955457:7,424,403...7,490,630
Ensembl chrNW_004955457:7,431,736...7,491,149
JBrowse link
G Csf1r colony stimulating factor 1 receptor disease_progression ISO associated with Diabetes Mellitus, Type 2 RGD PMID:19466391 RGD:2311340 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
JBrowse link
G Cst3 cystatin C ISO protein:increased expression:plasma (rat)
protein:increased expression:serum (human)
RGD PMID:18946178 PMID:19132849 RGD:2314297 RGD:2314328 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:plasma: RGD PMID:18026823 RGD:2312302 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460
JBrowse link
G Cubn cubilin ISO RGD PMID:17037740 RGD:1599655 NCBI chrNW_004955429:10,789,674...11,038,297
Ensembl chrNW_004955429:10,788,959...11,038,845
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:17425653 PMID:19073786 RGD:2311357 RGD:2311359 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927
JBrowse link
G Dcn decorin ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;mRNA, protein:decreased expression:kidney cortex, glomerulus
protein:increased expression:plasma, urine
RGD PMID:11259366 PMID:12187087 PMID:16868749 PMID:17884968 RGD:2311411 RGD:2311412 RGD:2311415 RGD:2311416 NCBI chrNW_004955405:28,335,493...28,371,912
Ensembl chrNW_004955405:28,332,545...28,372,323
JBrowse link
G Dgkh diacylglycerol kinase eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chrNW_004955518:4,104,700...4,263,657
Ensembl chrNW_004955518:4,113,265...4,208,449
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20019166 RGD:6907383 NCBI chrNW_004955425:7,353,964...7,357,599 JBrowse link
G Edn1 endothelin 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased secretion:plasma (human) RGD PMID:18346810 RGD:2313284 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
JBrowse link
G Ednra endothelin receptor type A ISO associated with Diabetes Mellitus, Experimental RGD PMID:21191784 RGD:4892326 NCBI chrNW_004955428:3,062,303...3,114,761
Ensembl chrNW_004955428:3,062,303...3,114,761
JBrowse link
G Egf epidermal growth factor ISO RGD PMID:17475821 RGD:6906912 NCBI chrNW_004955496:325,954...401,430
Ensembl chrNW_004955496:328,075...401,569
JBrowse link
G Elmo1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17942768 NCBI chrNW_004955460:6,044,827...6,580,770
Ensembl chrNW_004955460:6,044,725...6,581,269
JBrowse link
G Eng endoglin ISO associated with Diabetes Mellitus, Insulin-Dependent; mRNA:increased expression:kidney RGD PMID:19395281 RGD:2313795 NCBI chrNW_004955419:818,797...853,319
Ensembl chrNW_004955419:818,932...852,694
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:19506043 RGD:6906926 NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359
JBrowse link
G Ep300 E1A binding protein p300 treatment ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat) RGD PMID:19268536 RGD:2311716 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21832210 RGD:5688728 NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572
JBrowse link
G Epo erythropoietin ISO DNA:snp:promoter:-1125T>G(rs1617640)(human)
associated with Diabetes Mellitus, Experimental;
Protein:decreased expression:serum
RGD PMID:18458324 PMID:19356735 PMID:19619913 RGD:2313832 RGD:2313833 RGD:2313838 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney: RGD PMID:10749885 RGD:9685546 NCBI chrNW_004955486:4,941,143...4,955,693
Ensembl chrNW_004955486:4,941,143...4,955,693
JBrowse link
G Esr1 estrogen receptor 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:glomerulus
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:snps:introns: multiple(human)
RGD PMID:15550505 PMID:16464734 PMID:18305958 RGD:2314005 RGD:2314020 RGD:2314023 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G F2 coagulation factor II, thrombin disease_progression ISO protein:increased expression:plasma (human)
DNA:polymorphism: :20210G>A(human)
RGD PMID:14983223 PMID:21574459 PMID:21955218 RGD:2313643 RGD:6893574 RGD:6893575 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:15004866 RGD:2313863 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO DNA:polymorphism:CDS:amino acid A54T, in a Brazilian population RGD PMID:16249461 RGD:1578457 NCBI chrNW_004955428:20,930,512...20,933,950
Ensembl chrNW_004955428:20,930,479...20,933,950
JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney
associated with Diabetes Mellitus, Experimental;protein:increased expression:renal distal tubule (rat)
RGD PMID:12861046 PMID:17851466 PMID:18287563 RGD:2312739 RGD:2315705 RGD:8686421 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney RGD PMID:17851466 RGD:2315705 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Fbn1 fibrillin 1 onset ISO associated with Diabetes Mellitus, Experimental RGD PMID:16380460 PMID:16395273 RGD:7365077 RGD:7365080 NCBI chrNW_004955409:5,281,603...5,502,547
Ensembl chrNW_004955409:5,281,603...5,504,761
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO mRNA:increased expression:kidney RGD PMID:19279131 RGD:2315842 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:25625802 RGD:10401920 NCBI chrNW_004955559:1,818,400...1,821,423
Ensembl chrNW_004955559:1,817,110...1,820,417
JBrowse link
G Fgf23 fibroblast growth factor 23 severity ISO mRNA,protein:increased expression:kidney: RGD PMID:23967103 RGD:10044235 NCBI chrNW_004955413:2,182,459...2,192,279
Ensembl chrNW_004955413:2,182,459...2,192,279
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine RGD PMID:15610240 RGD:2313731 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Fmod fibromodulin ISO mRNA,protein:increased expression:Kidney Glomerulus
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:decreased expression:kidney cortex
RGD PMID:11259366 PMID:16868749 RGD:2311412 RGD:2311416 NCBI chrNW_004955406:39,328,743...39,340,113
Ensembl chrNW_004955406:39,328,743...39,340,258
JBrowse link
G Fn1 fibronectin 1 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney cortex:
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney
CTD
RGD
PMID:16301823 PMID:22736507 PMID:24413998 RGD:10402169 RGD:7206843 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased activity;urine RGD PMID:8343614 RGD:2315943 NCBI chrNW_004955452:3,744,071...3,759,776
Ensembl chrNW_004955452:3,744,755...3,759,676
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment ISO associated with Hypertension RGD PMID:21987533 RGD:10449128 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 NCBI chrNW_004955404:276,397...303,864
Ensembl chrNW_004955404:275,946...304,809
JBrowse link
G Gfpt1 glutamine--fructose-6-phosphate transaminase 1 ISO RGD PMID:9519709 RGD:2313353 NCBI chrNW_004955424:15,692,088...15,739,894
Ensembl chrNW_004955424:15,692,088...15,739,894
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP:3' utr RGD PMID:14764791 RGD:2307362 NCBI chrNW_004955408:330,112...372,413
Ensembl chrNW_004955408:330,112...372,413
JBrowse link
G Ghr growth hormone receptor susceptibility ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney RGD PMID:10541297 PMID:10614635 PMID:10990443 PMID:15066219 RGD:2307364 RGD:2307368 RGD:2307369 RGD:2307370 NCBI chrNW_004955426:26,553,509...26,873,619
Ensembl chrNW_004955426:26,689,581...26,871,684
JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO RGD PMID:19211686 RGD:2306734 NCBI chrNW_004955574:140,307...153,684
Ensembl chrNW_004955574:140,307...156,899
JBrowse link
G Glo1 glyoxalase I ISO DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003 RGD:7242569 NCBI chrNW_004955437:4,728,709...4,749,834
Ensembl chrNW_004955437:4,728,709...4,749,834
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:increased expression:glomerulus
associated with Diabetes Mellitus, Type 1
RGD PMID:16249459 PMID:17609286 RGD:11068479 RGD:2306609 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Gpx3 glutathione peroxidase 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:serum (human) RGD PMID:17269729 RGD:2312635 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chrNW_004955442:19,640,145...19,785,803
Ensembl chrNW_004955442:19,640,145...19,785,803
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO protein:decreased expression:cortex of kidney (rat) RGD PMID:23196710 RGD:13792785 NCBI chrNW_004955514:1,837,141...1,895,785
Ensembl chrNW_004955514:1,837,141...1,895,785
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chrNW_004955408:29,665,534...29,684,225
Ensembl chrNW_004955408:29,665,260...29,684,207
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO RGD PMID:26888388 RGD:13792773 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137
JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;protein:decreased activity:kidney
RGD PMID:23626958 PMID:24947049 RGD:10401899 RGD:7257582 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
G Has2 hyaluronan synthase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal medulla RGD PMID:18441392 RGD:9588630 NCBI chrNW_004955540:593,316...609,760
Ensembl chrNW_004955540:593,316...609,865
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression ISO associated with Diabetes mellitus, Type 1;
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
protein:increased expression:plasma
RGD PMID:20980978 PMID:22015481 PMID:22997966 RGD:7245497 RGD:7245960 RGD:7246890 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707
JBrowse link
G Hdac4 histone deacetylase 4 treatment ISO protein:increased expression:kidney:
mRNA,protein:increased expression:kidney:
RGD PMID:24717296 RGD:9590311 NCBI chrNW_004955542:1,629,691...1,886,160
Ensembl chrNW_004955542:1,629,691...1,886,210
JBrowse link
G Hdac5 histone deacetylase 5 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chrNW_004955451:17,223,217...17,246,451
Ensembl chrNW_004955451:17,223,287...17,244,051
JBrowse link
G Hfe homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:16340242 RGD:2313567 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2
RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21849637 RGD:10755581 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:17330940 RGD:7242762 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO mRNA,protein:increased expression:glomerulus:
protein:increased expression:glomerulus, podocyte:
RGD PMID:21931298 RGD:10402764 NCBI chrNW_004955844:8,094...9,565
Ensembl chrNW_004955844:7,790...10,004
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO associated with Diabetes Mellitus, Experimental;
associated with Diabetes Mellitus Type 2;
RGD PMID:12213354 PMID:18175064 RGD:7257686 RGD:7257687 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney (mouse)
associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.K469E (rs5498) (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
RGD PMID:18299691 PMID:18505543 PMID:19246972 PMID:20447389 RGD:2312766 RGD:2313470 RGD:2313475 RGD:4145414 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Ifng interferon gamma ISO mRNA, protein:increased expression:kidney, T cell RGD PMID:22286547 RGD:6893364 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf1 insulin like growth factor 1 ISO associated with Diabetes Mellitus, Experimental;protein:decreased expression:serum (rat) RGD PMID:10444029 PMID:17194636 RGD:12904967 RGD:2313764 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO mRNA,protein:increased expression:kidney: RGD PMID:19008912 RGD:10046022 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Igf2 insulin like growth factor 2 ISO associates with Diabetes Mellitus; mRNA:decreased expression:brain:
associated with Diabetes Mellitus, Type 2;
associated with Diabetes Mellitus, Type 2; mRNA:decreased expression:neural tissue, liver:
RGD PMID:8764603 PMID:9336345 RGD:5510019 RGD:5510022 NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
JBrowse link
G Igfbp1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chrNW_004955456:6,810,461...6,814,944
Ensembl chrNW_004955456:6,810,056...6,815,685
JBrowse link
G Il10 interleukin 10 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 RGD:2308943 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il1b interleukin 1 beta ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:19769609 PMID:22086159 RGD:7175266 RGD:7175519 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1rn interleukin 1 receptor antagonist no_association
susceptibility
ISO associated with Diabetes Mellitus, Type 2; DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:16174285 PMID:17286233 RGD:6907371 RGD:6909120 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il6 interleukin 6 susceptibility ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney (rat)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
RGD PMID:18716362 PMID:19052104 PMID:19542902 RGD:2307281 RGD:2307282 RGD:7829816 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ins insulin resistance ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:2143390 PMID:7713310 PMID:7987072 PMID:22068113 RGD:6902908 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Irs2 insulin receptor substrate 2 ISO mRNA:increased expression:kidney tubule: RGD PMID:23617393 RGD:7257702 NCBI chrNW_004955404:2,531,484...2,555,383
Ensembl chrNW_004955404:2,531,484...2,555,689
JBrowse link
G Itga2 integrin subunit alpha 2 severity ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:mesangial cell (human) RGD PMID:8989742 RGD:2307420 NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170
JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kdm6a lysine demethylase 6A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chrNW_004955516:3,151,350...3,346,832
Ensembl chrNW_004955516:3,149,948...3,346,832
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18630688 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Keap1 kelch like ECH associated protein 1 ISO RGD PMID:21439372 RGD:6893386 NCBI chrNW_004955495:1,704,695...1,711,339
Ensembl chrNW_004955495:1,704,695...1,711,290
JBrowse link
G Kl klotho treatment ISO protein:decreased expression:kidney: RGD PMID:24136780 RGD:10403079 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:17272402 PMID:19516248 RGD:1641794 NCBI chrNW_004955559:457,030...461,086
Ensembl chrNW_004955559:456,932...465,704
JBrowse link
G Klkb1 kallikrein B1 disease_progression ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389
JBrowse link
G Kng1 kininogen 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :7965C>T (human) RGD PMID:17065357 RGD:2311541 NCBI chrNW_004955420:20,989,197...21,016,084 JBrowse link
G Lamb2 laminin subunit beta 2 ISO RGD PMID:19864299 RGD:7207449 NCBI chrNW_004955532:1,115,412...1,127,264
Ensembl chrNW_004955532:1,115,087...1,127,455
JBrowse link
G Lep leptin ISO RGD PMID:22773754 RGD:6907074 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28130181 PMID:29988851 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
JBrowse link
G Lmna lamin A/C ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:cds:1908C>T (human) RGD PMID:16117820 RGD:2306095 NCBI chrNW_004955545:2,290,076...2,310,982
Ensembl chrNW_004955545:2,290,037...2,313,033
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO RGD PMID:1789335 RGD:2311543 NCBI chrNW_004955418:15,631,703...15,718,711
Ensembl chrNW_004955418:15,640,143...15,718,711
JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :242C>T (human) RGD PMID:14747204 RGD:8695982 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G LOC102023780 aromatase treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22301628 RGD:7257708 NCBI chrNW_004955409:3,198,622...3,313,072
Ensembl chrNW_004955409:3,266,233...3,313,142
JBrowse link
G LOC102027549 serotransferrin ISO RGD PMID:23468095 RGD:7244196 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910
JBrowse link
G Lpl lipoprotein lipase susceptibility ISO RGD PMID:16813599 RGD:2306755 NCBI chrNW_004955403:43,646,084...43,672,116
Ensembl chrNW_004955403:43,646,084...43,673,967
JBrowse link
G Lta lymphotoxin alpha ISO DNA:polymorphism RGD PMID:18575614 RGD:2313255 NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO RGD PMID:19923143 RGD:7243957 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activity:kidney RGD PMID:19066844 RGD:2311566 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083
JBrowse link
G Mdk midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:17607302 NCBI chrNW_004955422:1,655,351...1,657,026
Ensembl chrNW_004955422:1,655,358...1,657,044
JBrowse link
G Mfn2 mitofusin 2 treatment ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:26123583 PMID:27997345 RGD:11053290 RGD:12910740 NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772
JBrowse link
G Mllt3 MLLT3 super elongation complex subunit treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23077601 RGD:9686143 NCBI chrNW_004955434:22,594,681...22,873,826 JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO RGD PMID:21277817 RGD:7241216 NCBI chrNW_004955412:6,045,146...6,057,112
Ensembl chrNW_004955412:6,045,100...6,057,262
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23384615 RGD:13204971 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:repeat:promoter
RGD PMID:11576356 PMID:23384615 RGD:13204971 RGD:8547866 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility
ISO associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:14737040 PMID:18280442 RGD:6893524 RGD:6893576 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Mtor mechanistic target of rapamycin kinase susceptibility ISO DNA:SNP,haplotype: :rs7212142(human)
associated with Diabetes Mellitus, Experimental
RGD PMID:21606597 PMID:23827786 PMID:28536139 RGD:10003168 RGD:13506787 RGD:7245564 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO Associated with Diabetes Mellitus, Type 1;DNA:SNP:cds:66A>G, (rs1801394) (human) RGD PMID:18774994 RGD:6893652 NCBI chrNW_004955504:5,412,290...5,435,409
Ensembl chrNW_004955504:5,413,586...5,435,645
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 treatment ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney,glomerulus
associated with Diabetes Mellitus, Experimental
RGD PMID:22591908 PMID:22903132 RGD:13792578 RGD:8552684 NCBI chrNW_004955422:713,370...717,926
Ensembl chrNW_004955422:709,784...717,926
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:20103708 PMID:21439372 PMID:23064900 RGD:10412718 RGD:6893386 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
G Nos1 nitric oxide synthase 1 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2
RGD PMID:10966937 PMID:23548923 RGD:13824991 RGD:7257655 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
JBrowse link
G Nos3 nitric oxide synthase 3 treatment
susceptibility
no_association
ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10741691 PMID:10868974 PMID:20042665 PMID:29336891 RGD:13504726 RGD:7421530 RGD:7421534 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Nox4 NADPH oxidase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney cortex RGD PMID:16135519 PMID:17511984 RGD:2324670 RGD:2324673 NCBI chrNW_004955414:4,062,337...4,220,032
Ensembl chrNW_004955414:4,062,081...4,212,746
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:decreased expression:kidney (mouse)
RGD PMID:17624267 PMID:21617141 PMID:24173355 PMID:30862474 RGD:38596322 RGD:38596325 RGD:38599008 RGD:7241083 NCBI chrNW_004955468:2,715,728...2,734,174
Ensembl chrNW_004955468:2,714,419...2,734,830
JBrowse link
G Nppa natriuretic peptide A disease_progression
no_association
ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :2238T>C (human)
DNA:polymorphism:intron
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:blood
RGD PMID:9681733 PMID:10381153 PMID:10404802 PMID:15111511 RGD:2313590 RGD:2313592 RGD:2313593 RGD:7247731 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003
JBrowse link
G Nppb natriuretic peptide B ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:10404802 PMID:16917760 RGD:7247731 RGD:7248603 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21457706 RGD:11035226 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:20557422 RGD:4891134 NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20621183 RGD:11073737 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
JBrowse link
G Pax2 paired box 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney cortex RGD PMID:15149326 RGD:2316747 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:increased expression:kidney RGD PMID:12808179 RGD:2311649 NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:glomerulus RGD PMID:15042541 RGD:2311655 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
JBrowse link
G Pgf placental growth factor disease_progression ISO associated with Diabetes Mellitus, Type 1 RGD PMID:21988672 RGD:6483606 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
JBrowse link
G Plat plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16598198 RGD:2311671 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
JBrowse link
G Plau plasminogen activator, urokinase ISO mRNA:increased expression:renal glomerulus (rat) RGD PMID:15322501 RGD:1580123 NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209
JBrowse link
G Pon1 paraoxonase 1 no_association
susceptibility
ISO associated with Diabetes Mellitus;DNA:missense mutations:cds:p.L55M, p.Q192R (rs854560, rs662) (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15270786 PMID:19207863 PMID:24100645 PMID:26884296 RGD:2313266 RGD:8547548 RGD:8547572 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Pon2 paraoxonase 2 ISO associated with type 2 diabetes mellitus;DNA:polymorphisms:multiple
associated with type 1 diabetes mellitus;DNA:missense mutation:cds:p.C311S (human)
RGD PMID:11206400 PMID:11918623 RGD:1580218 RGD:2313492 NCBI chrNW_004955432:11,988,009...12,020,702
Ensembl chrNW_004955432:11,987,919...12,020,740
JBrowse link
G Postn periostin ISO mRNA,protein:increased expression:kidney: RGD PMID:22167593 RGD:10040972 NCBI chrNW_004955431:8,510,646...8,544,901
Ensembl chrNW_004955431:8,510,624...8,544,971
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18388116 PMID:18780770 PMID:28182703 RGD:2301845 RGD:2301862 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO DNA:polymorphism:exon:p.G482S (human)
mRNA:decreased expression:kidney (human)
RGD PMID:19900151 PMID:21784897 RGD:7242027 RGD:7242045 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
JBrowse link
G Prkcb protein kinase C beta ISO associated with hypertension;protein:increased expression:glomerular mesangium RGD PMID:12540629 RGD:729635 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934
JBrowse link
G Prkce protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chrNW_004955441:12,642,703...13,142,396
Ensembl chrNW_004955441:12,642,697...13,139,372
JBrowse link
G Prmt1 protein arginine methyltransferase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23159951 RGD:9491822 NCBI chrNW_004955559:1,205,340...1,215,672
Ensembl chrNW_004955559:1,203,283...1,215,021
JBrowse link
G Pros1 protein S treatment
severity
ISO associated with diabetes mellitus, experimental;mRNA, protein:increased expression:kidney, glomerulus RGD PMID:29511111 RGD:13515131 NCBI chrNW_004955407:3,514,900...3,566,165
Ensembl chrNW_004955407:3,535,388...3,565,058
JBrowse link
G Pten phosphatase and tensin homolog ISO protein:decreased expression:kidney cortex, glomerulus RGD PMID:16804083 RGD:2292546 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829
JBrowse link
G Ptgds prostaglandin D2 synthase susceptibility ISO RGD PMID:15970590 RGD:1642581 NCBI chrNW_004955513:5,009,530...5,012,781 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17112505 PMID:21441310 RGD:5135032 RGD:5688268 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Pth parathyroid hormone ISO DNA:snps:exon, intron:g.350C>A, g.IVS2+56G>A (rs6256, rs6254) (human) RGD PMID:22777106 RGD:7242744 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17900838 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
JBrowse link
G Ren renin ISO RGD PMID:15489960 RGD:1579795 NCBI chrNW_004955406:40,016,624...40,026,286
Ensembl chrNW_004955406:40,016,630...40,026,286
JBrowse link
G Retn resistin ISO RGD PMID:21425555 RGD:7207159 NCBI chrNW_004955563:1,607,814...1,609,273
Ensembl chrNW_004955563:1,607,814...1,609,273
JBrowse link
G Selp selectin P severity ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney, serum
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD PMID:18026823 PMID:18471420 RGD:2312294 RGD:2312302 NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
JBrowse link
G Serpinb7 serpin family B member 7 ISO associated with Diabetes Mellitus, Type 2;DNA:SNP:intron:rs1720843 (human)
associated with Diabetes Mellitus, Type 1
RGD PMID:16443768 PMID:19690890 RGD:7207374 RGD:7207378 NCBI chrNW_004955402:47,599,503...47,649,537
Ensembl chrNW_004955402:47,599,150...47,649,885
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus, mesangial cell (rat)
associate with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
CTD
RGD
PMID:10809802 PMID:15322501 PMID:18682491 PMID:26712211 RGD:11073694 RGD:1580123 RGD:8547711 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma (human)
human protein in a mouse model
mRNA, protein:decreased expression:renal cortex, renal medulla (rat)
RGD PMID:15616035 PMID:18523656 PMID:23884140 RGD:1359799 RGD:8554865 RGD:8554896 NCBI chrNW_004955481:1,414,930...1,426,436
Ensembl chrNW_004955481:1,414,930...1,426,241
JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment ISO associated with Diabetes Mellitus, Type 2;DNA:SNP:exon:g.20882C>T (human)
associated with Diabetes Mellitus, Experimental
RGD PMID:15745834 PMID:22707888 PMID:26337659 RGD:12879466 RGD:12879861 RGD:2312305 NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511
JBrowse link
G Smad6 SMAD family member 6 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17437042 RGD:2289036 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Sod1 superoxide dismutase 1 ISO protein:decreased expression:kidney
human gene in a mouse model
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple
RGD PMID:11522679 PMID:17914031 PMID:19470681 RGD:2312361 RGD:2312365 RGD:8655571 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17192491 PMID:24819633 RGD:7175540 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
G Sod3 superoxide dismutase 3 ISO protein:decreased expression:kidney RGD PMID:19470681 RGD:2312361 NCBI chrNW_004955480:257,716...263,149 JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:kidney RGD PMID:8569083 RGD:2300072 NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12032186 RGD:1581328 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney
RGD PMID:16046298 PMID:16936198 PMID:17961514 PMID:18613221 RGD:1581418 RGD:2308806 RGD:2308811 RGD:2308815 NCBI chrNW_004955577:171,425...183,669
Ensembl chrNW_004955577:171,425...186,046
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney RGD PMID:16046298 PMID:16936198 RGD:1581418 RGD:2308815 NCBI chrNW_004955413:27,271,717...27,326,655
Ensembl chrNW_004955413:27,271,953...27,326,759
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP (human) RGD PMID:19506043 RGD:6906926 NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134
JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO mRNA:increased expression:glomerulus
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18682491 PMID:19211686 PMID:19960420 PMID:24074026 RGD:2306734 RGD:7394855 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tgfbi transforming growth factor beta induced ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12911551 PMID:18682491 RGD:1304421 NCBI chrNW_004955408:31,093,450...31,124,715
Ensembl chrNW_004955408:31,093,050...31,125,398
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496156 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837
JBrowse link
G Tgif1 TGFB induced factor homeobox 1 ISO protein:decreased expression:glomerulus (rat) RGD PMID:15153551 RGD:1599409 NCBI chrNW_004955402:7,130,809...7,138,945
Ensembl chrNW_004955402:7,129,484...7,138,340
JBrowse link
G Thbs1 thrombospondin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17878288 RGD:2317941 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:kidney RGD PMID:17491697 RGD:2290407 NCBI chrNW_004955506:3,769,113...3,812,896
Ensembl chrNW_004955506:3,768,646...3,813,820
JBrowse link
G Tinag tubulointerstitial nephritis antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chrNW_004955411:1,718,969...1,809,370
Ensembl chrNW_004955411:1,717,026...1,810,055
JBrowse link
G Tlr2 toll like receptor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21617141 RGD:7241083 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
G Tlr4 toll like receptor 4 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22021706 RGD:7207902 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tnf tumor necrosis factor ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:urine RGD PMID:12969138 PMID:16141456 PMID:16336586 PMID:21441310 RGD:1580208 RGD:1580296 RGD:1580311 RGD:5135032 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfaip1 TNF alpha induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chrNW_004955481:4,786,015...4,799,376
Ensembl chrNW_004955481:4,786,015...4,799,274
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b treatment
disease_progression
ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Type 1
RGD PMID:18719882 PMID:20727867 RGD:7205493 RGD:7205514 NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2
RGD PMID:19073786 PMID:22042131 RGD:2311357 RGD:7245547 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B onset ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
RGD PMID:16408124 PMID:19073786 PMID:22266664 RGD:2311357 RGD:7245476 RGD:7245529 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO protein:increased expression:kidney RGD PMID:18287563 RGD:2312739 NCBI chrNW_004955420:2,550,392...2,566,448
Ensembl chrNW_004955420:2,549,142...2,566,564
JBrowse link
G Tp53 tumor protein p53 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17901943 RGD:2290561 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26097534 RGD:11535148 NCBI chrNW_004955495:2,770,449...2,780,650
Ensembl chrNW_004955495:2,770,713...2,780,568
JBrowse link
G Trpc1 transient receptor potential cation channel subfamily C member 1 ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chrNW_004955508:3,143,868...3,211,613
Ensembl chrNW_004955508:3,143,868...3,211,613
JBrowse link
G Trpc6 transient receptor potential cation channel subfamily C member 6 treatment
induces
ISO associated with Diabetes Mellitus, Experimental RGD PMID:22673147 PMID:29923767 RGD:149735534 RGD:7247584 NCBI chrNW_004955412:4,905,039...5,019,678
Ensembl chrNW_004955412:4,906,650...4,950,525
JBrowse link
G Txnip thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582205 NCBI chrNW_004955568:103,801...107,791
Ensembl chrNW_004955568:103,762...107,785
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine (human) RGD PMID:17634209 RGD:2311211 NCBI chrNW_004955524:3,007,074...3,009,886
Ensembl chrNW_004955524:3,006,147...3,018,772
JBrowse link
G Ucp1 uncoupling protein 1 no_association ISO DNA:SNP: :-3826A>G (human) RGD PMID:15120704 RGD:7247625 NCBI chrNW_004955428:3,253,363...3,282,518
Ensembl chrNW_004955428:3,274,810...3,283,237
JBrowse link
G Ucp2 uncoupling protein 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22848482 RGD:7175295 NCBI chrNW_004955414:17,592,914...17,596,477
Ensembl chrNW_004955414:17,592,914...17,596,477
JBrowse link
G Uts2 urotensin 2 disease_progression ISO mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
RGD PMID:15476950 PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 RGD:2306806 NCBI chrNW_004955486:5,052,045...5,056,610
Ensembl chrNW_004955486:5,052,045...5,056,610
JBrowse link
G Uts2r urotensin 2 receptor ISO mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 NCBI chrNW_004955506:756,859...761,891 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:kidney
associated with Diabetes Mellitus,Type 1;protein:increased expression:plasma:
RGD PMID:20138682 PMID:23303408 RGD:7240523 RGD:7241237 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691
JBrowse link
G Vdac1 voltage dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chrNW_004955408:5,260,444...5,275,972 JBrowse link
G Vdac2 voltage dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chrNW_004955437:16,857,715...16,871,717
Ensembl chrNW_004955437:16,853,433...16,872,345
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15610240 PMID:18630688 RGD:2313731 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vtn vitronectin ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:glomerulus RGD PMID:11728964 RGD:10003096 NCBI chrNW_004955481:4,765,078...4,768,027 JBrowse link
G Xylt1 xylosyltransferase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:missense mutation:cds:p.A115S (human) RGD PMID:17003309 RGD:2313138 NCBI chrNW_004955442:1,787,338...2,042,523
Ensembl chrNW_004955442:1,745,924...2,036,340
JBrowse link
diabetic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2b adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism (human) RGD PMID:17516297 RGD:2313542 NCBI chrNW_004955470:3,711,075...3,714,450
Ensembl chrNW_004955470:3,711,031...3,714,241
JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22171162 RGD:8695979 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15318096 RGD:2311150 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:20724598 RGD:5509623 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:20587056 RGD:5129222 NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
JBrowse link
G Bdnf brain derived neurotrophic factor ISO associated with Diabetes Mellitus, Experimental RGD PMID:20557422 RGD:4891134 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Becn1 beclin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25824552 RGD:11561957 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Casp3 caspase 3 ISO associated with Diabetes Mellitus, Experimental;protein:increased expresssion:sciatic nerve
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12502508 PMID:19555701 RGD:2311441 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10780678 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Cav1 caveolin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:19675140 RGD:8661787 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus;protein:increased expression:serum RGD PMID:19276232 RGD:2307060 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Cd63 CD63 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:platelet RGD PMID:10547212 RGD:2314203 NCBI chrNW_004955458:3,362,511...3,363,916
Ensembl chrNW_004955458:3,362,511...3,363,981
JBrowse link
G Chrm2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20624991 NCBI chrNW_004955494:5,845,581...5,975,614
Ensembl chrNW_004955494:5,847,156...5,848,556
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18810243 RGD:2314631 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
JBrowse link
G Epo erythropoietin ISO associated with Diabetes Mellitus, Experimental; RGD PMID:19244253 RGD:2313834 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:altered expression:plasma (human) RGD PMID:10468085 RGD:2312401 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:16644707 RGD:2315860 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus,Insulin-Dependent;protein:increased activity:serum RGD PMID:11311965 RGD:2315614 NCBI chrNW_004955455:8,082,578...8,099,523 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO associated with Diabetes Mellitus, Experimental RGD PMID:19733151 RGD:2313744 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812
JBrowse link
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19840219 NCBI chrNW_004955414:4,424,245...4,919,399 JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental
CTD
RGD
PMID:15734864 PMID:26000320 RGD:2313570 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Hhip hedgehog interacting protein ISO RGD PMID:19515211 RGD:11552601 NCBI chrNW_004955428:657,918...745,255
Ensembl chrNW_004955428:657,900...745,250
JBrowse link
G Ifng interferon gamma ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :874A>T (human) RGD PMID:19608431 RGD:2311489 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf1 insulin like growth factor 1 treatment ISO associated with Diabetes Mellitus, Experimental
protein:decreased expression:serum
RGD PMID:17194636 PMID:18545223 PMID:19264110 RGD:2306687 RGD:2313764 RGD:8549454 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:23280817 RGD:7401217 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Insr insulin receptor ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;protein:decreased phosphorylation:sciatic nerve
CTD
RGD
PMID:18331706 RGD:2307344 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24263156 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:cerebellum, Purkinje cell RGD PMID:24810053 RGD:13462056 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18579738 RGD:2311567 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083
JBrowse link
G Mbp myelin basic protein ISO associated with Diabetes Mellitus, Experimental; protein:decreased expression:sciatic nerve: RGD PMID:23735240 RGD:7327194 NCBI chrNW_004955402:60,324,060...60,448,926
Ensembl chrNW_004955402:60,323,950...60,441,406
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G Mme membrane metalloendopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20148083 NCBI chrNW_004955448:6,193,113...6,311,666
Ensembl chrNW_004955448:6,226,059...6,314,949
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G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
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G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
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G Mpz myelin protein zero treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22158827 RGD:9685782 NCBI chrNW_004955468:13,041,911...13,047,026
Ensembl chrNW_004955468:13,041,011...13,047,284
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G Ngf nerve growth factor ISO mRNA,protein:decreased expression:sciatic nerve RGD PMID:12469361 RGD:5508379 NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
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G Ngfr nerve growth factor receptor <