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ONTOLOGY REPORT - ANNOTATIONS


Term:adrenocortical carcinoma
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Accession:DOID:3948 term browser browse the term
Definition:A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.
Synonyms:exact_synonym: Adrenal Cortical Carcinomas;   adrenal cortical carcinoma;   adrenocortical carcinomas;   carcinoma of the adrenal cortex
 primary_id: MESH:D018268
 alt_id: RDO:0007151
 xref: GARD:558;   NCI:C9325
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adrenocortical carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11554173
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:11554173
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:11554173
RGD:8554872
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:11554173
RGD:8554872
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:11554173
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:11554173
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
G H3f3a H3 histone family member 3A JBrowse link 13 99,091,246 99,102,828 RGD:8554872
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:11554173
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:11554173
G Med12 mediator complex subunit 12 JBrowse link X 71,174,653 71,197,812 RGD:11554173
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:11554173
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:8554872
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:11554173
G Rrm1 ribonucleotide reductase catalytic subunit M1 JBrowse link 1 167,538,387 167,562,688 RGD:11554173
G Sparc secreted protein acidic and cysteine rich JBrowse link 10 40,742,390 40,764,232 RGD:11554173
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11554173
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
RGD:8554872
G Znrf3 zinc and ring finger 3 JBrowse link 14 85,527,099 85,586,294 RGD:11554173
Hereditary Adrenocortical Carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:7240710
RGD:8554872
Pediatric Adrenocortical Carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15992
    disease of anatomical entity 15263
      endocrine system disease 4935
        endocrine gland cancer 1447
          adrenal gland cancer 23
            adrenal cortex cancer 22
              adrenocortical carcinoma 22
                Hereditary Adrenocortical Carcinoma 1
                Pediatric Adrenocortical Carcinoma 1
                adrenal cortical adenocarcinoma 0
Path 2
Term Annotations click to browse term
  disease 15992
    disease of cellular proliferation 5887
      Neoplasms by Site 5261
        Endocrine Gland Neoplasms 1655
          endocrine gland cancer 1447
            adrenal gland cancer 23
              adrenal cortex cancer 22
                adrenocortical carcinoma 22
                  Hereditary Adrenocortical Carcinoma 1
                  Pediatric Adrenocortical Carcinoma 1
                  adrenal cortical adenocarcinoma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.