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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Arenaviridae infectious disease
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Accession:DOID:3944 term browser browse the term
Definition:A viral infectious disease that results_in infection in rodents and humans, has_material_basis_in Arenaviridae viruses. (DO)
Synonyms:exact_synonym: Arenaviridae Infection;   Arenavirus Infection;   arenaviridae infections;   arenavirus infections
 primary_id: MESH:D001117
 xref: EFO:0007150
For additional species annotation, visit the Alliance of Genome Resources.



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Arenaviridae infectious disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO RGD PMID:21641396 RGD:126779561 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G CD1D CD1d molecule ISO RGD PMID:32153566 RGD:127345122 NCBI chr38:23,489,169...23,491,712 JBrowse link
G IL21 interleukin 21 ISO RGD PMID:21423809 RGD:127285543 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL27 interleukin 27 ISO mRNA, protein:increased expression:spleen (mouse) RGD PMID:29593047 RGD:126790521 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:11927625 RGD:150340679 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G STAT2 signal transducer and activator of transcription 2 ameliorates ISO RGD PMID:15723812 RGD:41789630 NCBI chr10:641,543...660,882
Ensembl chr10:642,718...658,546
JBrowse link
G TFRC transferrin receptor ISO CTD Direct Evidence: therapeutic CTD PMID:17287727 NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242
JBrowse link
Lassa fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAG1 dystroglycan 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17287727 NCBI chr20:39,707,672...39,779,094
Ensembl chr20:39,708,053...39,778,550
JBrowse link
lymphocytic choriomeningitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule ISO RGD PMID:23230000 RGD:41410802 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522
JBrowse link
G CLEC12A C-type lectin domain family 12 member A disease_progression ISO RGD PMID:31451663 RGD:41412202 NCBI chr27:36,040,574...36,051,249
Ensembl chr27:36,040,577...36,051,184
JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 disease_progression ISO DNA:mutation: : RGD PMID:24760883 PMID:28878077 RGD:124715467 RGD:124715479 NCBI chr31:28,854,765...28,876,399 JBrowse link
G IFNGR1 interferon gamma receptor 1 ameliorates ISO RGD PMID:22496215 RGD:124715469 NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity ISO RGD PMID:25829541 RGD:40400708 NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357
JBrowse link
G IL21R interleukin 21 receptor ISO RGD PMID:19478140 RGD:6892934 NCBI chr 6:19,181,846...19,217,915
Ensembl chr 6:19,182,071...19,217,931
JBrowse link
G IRF7 interferon regulatory factor 7 disease_progression ISO RGD PMID:24760883 RGD:124715479
G IRF9 interferon regulatory factor 9 ameliorates
disease_progression
ISO DNA:mutation: : RGD PMID:22496215 PMID:24760883 PMID:28878077 RGD:124715467 RGD:124715469 RGD:124715479 NCBI chr 8:4,152,146...4,157,201 JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 ISO RGD PMID:30995287 RGD:40818298 NCBI chr 1:102,686,058...102,690,350
Ensembl chr 1:102,686,058...102,690,620
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20565293 RGD:40902858 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 disease_progression ISO RGD PMID:20565293 RGD:40902858 NCBI chr28:14,902,212...14,910,437
Ensembl chr28:14,902,706...14,910,395
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO RGD PMID:23230000 PMID:30726291 RGD:40818232 RGD:41410802 NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723
JBrowse link
G STAT1 signal transducer and activator of transcription 1 exacerbates ISO RGD PMID:22496215 RGD:124715469 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178
JBrowse link
G STAT2 signal transducer and activator of transcription 2 ISO RGD PMID:24760883 PMID:32094187 RGD:124715479 RGD:42722006 NCBI chr10:641,543...660,882
Ensembl chr10:642,718...658,546
JBrowse link
G WAS WASP actin nucleation promoting factor ISO RGD PMID:23141740 RGD:38676258 NCBI chr  X:41,882,240...41,890,053
Ensembl chr  X:41,882,875...41,890,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17773
    disease by infectious agent 2127
      viral infectious disease 1623
        RNA Virus Infections 1362
          Arenaviridae infectious disease 22
            Arenavirus hemorrhagic fever + 0
            Bolivian hemorrhagic fever 0
            Lassa fever 1
            lymphocytic choriomeningitis 15
paths to the root