|
G |
Abcb1 |
ATP binding cassette subfamily B member 1 |
treatment |
ISO |
DNA:SNPs: :2677G>T, 3435C>T(human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:17534875 PMID:20627363 |
RGD:11080964 |
NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
treatment |
ISO |
DNA:SNPs: :-24C>T, 3972C>T(human) |
RGD |
PMID:17534875 |
RGD:11080964 |
NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:26758680 |
RGD:126925226 |
NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669
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G |
Acvr1b |
activin A receptor type 1B |
susceptibility |
ISO |
DNA:SNP:intron:rs12809597(human) |
RGD |
PMID:22586632 |
RGD:151665491 |
NCBI chrNW_004936512:9,407,578...9,449,611
Ensembl chrNW_004936512:9,407,581...9,449,632
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G |
Ada |
adenosine deaminase |
|
ISO |
protein:decreased expression:lymphocyte,erythrocyte: |
RGD |
PMID:31375946 |
RGD:152995295 |
NCBI chrNW_004936530:2,217,713...2,224,070
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G |
Adam28 |
ADAM metallopeptidase domain 28 |
treatment |
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:21429053 PMID:22354764 |
RGD:153297789 RGD:153298914 |
NCBI chrNW_004936555:7,615,639...7,660,776
Ensembl chrNW_004936555:7,617,822...7,664,215
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19027488 |
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NCBI chrNW_004936640:959,405...967,305
Ensembl chrNW_004936640:959,417...968,842
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G |
Ager |
advanced glycosylation end-product specific receptor |
|
ISO |
mRNA, protein:decreased expression:lung (human) |
RGD |
PMID:15539404 |
RGD:7245515 |
NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147
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G |
Akt1 |
AKT serine/threonine kinase 1 |
treatment ameliorates |
ISO |
human cells in mouse model human cells in mouse model |
RGD |
PMID:23632475 PMID:32276600 |
RGD:150404268 RGD:151357000 |
NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
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G |
Akt3 |
AKT serine/threonine kinase 3 |
disease_progression |
ISO |
|
RGD |
PMID:19846969 |
RGD:13432583 |
NCBI chrNW_004936526:6,944,056...7,201,226
Ensembl chrNW_004936526:6,944,005...7,200,583
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G |
Alk |
ALK receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17625570 PMID:20979469 PMID:20979473 PMID:21102269 PMID:21336183 PMID:21587085 PMID:21757253 PMID:21767331 PMID:21791641 PMID:21823889 PMID:21904575 PMID:21933749 PMID:22215748 PMID:22277784 PMID:22282074 PMID:22286583 PMID:22508824 PMID:22568572 PMID:22617245 PMID:22713522 PMID:22787409 PMID:22887466 PMID:22920921 PMID:22954507 PMID:22968692 PMID:22986231 PMID:23020724 PMID:23686600 More...
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NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874
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G |
Amd1 |
adenosylmethionine decarboxylase 1 |
disease_progression |
ISO |
DNA:SNP: :rs1279590(human) |
RGD |
PMID:30650190 |
RGD:14390072 |
NCBI chrNW_004936564:6,656,789...6,675,564
Ensembl chrNW_004936564:6,656,746...6,673,462
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
|
ISO |
mRNA:decreased expression:lung |
RGD |
PMID:28982084 |
RGD:13703106 |
NCBI chrNW_004936492:14,818,561...14,902,231
Ensembl chrNW_004936492:14,816,623...14,902,132
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G |
Apc |
APC regulator of WNT signaling pathway |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18337602 |
|
NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453
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G |
Areg |
amphiregulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 PMID:16230376 |
|
NCBI chrNW_004936598:1,276,599...1,283,612
Ensembl chrNW_004936598:1,274,565...1,283,746
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G |
Arid1a |
AT-rich interaction domain 1A |
treatment disease_progression |
ISO |
DNA:mutations protein:decreased expression:lung (human) |
RGD |
PMID:24566899 PMID:32791957 |
RGD:126848781 RGD:126848874 |
NCBI chrNW_004936474:11,148,857...11,197,312
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G |
Arid1b |
AT-rich interaction domain 1B |
treatment |
ISO |
DNA:mutations |
RGD |
PMID:32791957 |
RGD:126848874 |
NCBI chrNW_004936489:8,811,094...9,202,423
Ensembl chrNW_004936489:9,087,697...9,205,203
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G |
Arpc5 |
actin related protein 2/3 complex subunit 5 |
|
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:22089643 |
RGD:11049488 |
NCBI chrNW_004936481:6,267,133...6,276,173
Ensembl chrNW_004936481:6,267,091...6,278,170
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G |
Atf3 |
activating transcription factor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
|
NCBI chrNW_004936557:909,302...922,619
Ensembl chrNW_004936557:908,318...922,624
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G |
Atm |
ATM serine/threonine kinase |
susceptibility treatment |
ISO |
DNA:SNPs,haplotypes:intron: (rs227060, rs170548) (human) human cells in mouse model |
RGD |
PMID:17582598 PMID:23632475 |
RGD:150383340 RGD:150404268 |
NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
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G |
Aven |
apoptosis and caspase activation inhibitor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
|
NCBI chrNW_004936673:2,434,984...2,568,868
Ensembl chrNW_004936673:2,435,308...2,565,180
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G |
Axin1 |
axin 1 |
disease_progression |
ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:19735876 |
RGD:150530290 |
NCBI chrNW_004936501:599,963...633,837
Ensembl chrNW_004936501:599,919...633,873
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G |
Axl |
AXL receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:22751098 |
|
NCBI chrNW_004936661:3,658,140...3,687,290
Ensembl chrNW_004936661:3,657,831...3,687,816
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G |
Bad |
BCL2 associated agonist of cell death |
disease_progression |
ISO |
protein:decreased expression:lung |
RGD |
PMID:21918885 PMID:24092988 |
RGD:13432584 RGD:13434906 |
NCBI chrNW_004936599:4,924,349...4,933,683
Ensembl chrNW_004936599:4,924,789...4,933,368
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G |
Bag6 |
BAG cochaperone 6 |
susceptibility |
ISO |
DNA:SNP: :rs3117582(human) |
RGD |
PMID:25884493 |
RGD:14390136 |
NCBI chrNW_004936727:1,866,235...1,885,266
Ensembl chrNW_004936727:1,873,413...1,885,366
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G |
Bambi |
BMP and activin membrane bound inhibitor |
|
ISO |
mRNA,protein:increased expression:lung: |
RGD |
PMID:20716422 |
RGD:14390157 |
NCBI chrNW_004936613:3,098,549...3,103,868
Ensembl chrNW_004936613:3,098,159...3,103,868
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G |
Bard1 |
BRCA1 associated RING domain 1 |
disease_progression |
ISO |
|
RGD |
PMID:21815143 |
RGD:127229947 |
NCBI chrNW_004936586:2,200,211...2,272,781
Ensembl chrNW_004936586:2,200,205...2,273,307
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G |
Bax |
BCL2 associated X, apoptosis regulator |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820
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G |
Bbc3 |
BCL2 binding component 3 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936664:962,115...966,797
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|
G |
Bcl11a |
BCL11 transcription factor A |
severity |
ISO |
mRNA, protein:increased expression:lung (human) |
RGD |
PMID:23758992 |
RGD:11099968 |
NCBI chrNW_004936491:6,021,340...6,118,103
Ensembl chrNW_004936491:6,021,343...6,118,568
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G |
Bcorl1 |
BCL6 corepressor like 1 |
severity |
ISO |
|
RGD |
PMID:26648304 |
RGD:11342082 |
NCBI chrNW_004936479:1,539,676...1,605,647
Ensembl chrNW_004936479:1,538,051...1,606,344
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G |
Bend4 |
BEN domain containing 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28722770 |
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NCBI chrNW_004936482:9,318,875...9,352,735
Ensembl chrNW_004936482:9,327,469...9,346,905
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G |
Birc2 |
baculoviral IAP repeat containing 2 |
exacerbates |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:27737687 |
RGD:152998985 |
NCBI chrNW_004936551:5,515,904...5,535,864
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G |
Birc3 |
baculoviral IAP repeat containing 3 |
exacerbates ameliorates |
ISO |
protein:increased expression:lung (human) DNA:SNP:intron: (rs11225211) (human) |
RGD |
PMID:20959404 PMID:27737687 PMID:32905523 |
RGD:152998985 RGD:152999005 RGD:153297804 |
NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555
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G |
Birc5 |
baculoviral IAP repeat containing 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16382892 |
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NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
|
ISO |
ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:2102266 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 PMID:12619120 PMID:12644542 PMID:12670889 PMID:12794760 PMID:12960123 PMID:14513361 PMID:14602780 PMID:14612909 PMID:14681681 PMID:14688025 PMID:15001635 PMID:15016963 PMID:15035987 PMID:15046639 PMID:15126572 PMID:15181070 PMID:15342696 PMID:15356022 PMID:15386408 PMID:15488754 PMID:15687339 PMID:15753399 PMID:15998781 PMID:16015629 PMID:16174717 PMID:16187918 PMID:16772349 PMID:17096326 PMID:17119447 PMID:17311103 PMID:17314276 PMID:17374713 PMID:17488796 PMID:17785355 PMID:18039235 PMID:18368129 PMID:18398503 PMID:18413255 PMID:19206169 PMID:19363522 PMID:19376813 PMID:19383316 PMID:19571295 PMID:19593635 PMID:19794125 PMID:19913317 PMID:20186801 PMID:20818844 PMID:20823850 PMID:21107320 PMID:21107323 PMID:21190184 PMID:21204800 PMID:21343559 PMID:21716161 PMID:22039425 PMID:22113612 PMID:22281684 PMID:22535154 PMID:22892241 PMID:23093928 PMID:23302800 PMID:23352452 PMID:23680146 PMID:23685455 PMID:23756559 PMID:23907581 PMID:24033266 PMID:24512911 PMID:24670642 PMID:24717435 PMID:25079330 PMID:25155755 PMID:25741868 PMID:25950823 PMID:28492532 PMID:28854169 PMID:29595366 PMID:29925953 PMID:31891627 PMID:32978145 PMID:33522658 PMID:34476331 More...
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NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
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G |
Brca1 |
BRCA1 DNA repair associated |
treatment disease_progression |
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:21575522 PMID:23128816 PMID:23335114 PMID:24443257 |
RGD:126925968 RGD:127229935 RGD:127229948 RGD:127229949 |
NCBI chrNW_004936490:17,735,444...17,801,456
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G |
Brd7 |
bromodomain containing 7 |
disease_progression |
ISO |
protein:increased expression:lung: |
RGD |
PMID:22008115 |
RGD:9586442 |
NCBI chrNW_004936475:3,394,423...3,432,998
Ensembl chrNW_004936475:3,393,373...3,433,103
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G |
Btk |
Bruton tyrosine kinase |
ameliorates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:32623229 |
RGD:151347854 |
NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441
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G |
Ca12 |
carbonic anhydrase 12 |
disease_progression |
ISO |
|
RGD |
PMID:20521252 PMID:23910904 |
RGD:155226863 RGD:155226864 |
NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987
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G |
Ca9 |
carbonic anhydrase 9 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:23910904 PMID:30381462 |
RGD:155226863 |
NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433
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G |
Calr |
calreticulin |
ameliorates |
ISO |
protein:increased expression:lung (human) mRNA, protein:increased expression:lung (human) |
RGD |
PMID:26842877 PMID:29228584 |
RGD:150521685 RGD:150521696 |
NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430
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G |
Casp3 |
caspase 3 |
|
ISO |
mRNA:increased expression:lung DNA:SNP: :77G>A (human) |
RGD |
PMID:16231180 PMID:20661084 |
RGD:13434908 RGD:13434909 |
NCBI chrNW_004936554:4,571,072...4,593,765
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G |
Casp6 |
caspase 6 |
|
ISO |
mRNA:increased expression:lung |
RGD |
PMID:16231180 |
RGD:13434909 |
NCBI chrNW_004936563:912,502...920,025
Ensembl chrNW_004936563:911,304...919,119
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G |
Casp7 |
caspase 7 |
|
ISO |
DNA:SNP: :rs2227310 (human) |
RGD |
PMID:20661084 |
RGD:13434908 |
NCBI chrNW_004936486:4,082,664...4,114,942
Ensembl chrNW_004936486:4,088,372...4,114,955
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G |
Casp8 |
caspase 8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20471133 |
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NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
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G |
Casp9 |
caspase 9 |
no_association |
ISO |
mRNA:splice variant:lung mRNA:increased expression:lung DNA:SNP:exon:rs1052571 (human) DNA, mRNA:SNP, decreased expression:exon, lung:rs1052576 (human) DNA:SNP: :rs4645981 (human) |
RGD |
PMID:16231180 PMID:17285546 PMID:20661084 PMID:20972334 |
RGD:13434907 RGD:13434908 RGD:13434909 RGD:9999427 |
NCBI chrNW_004936474:3,178,097...3,196,130
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G |
Cat |
catalase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11731445 |
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NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422
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G |
Cbl |
Cbl proto-oncogene |
|
ISO |
DNA:missense mutations, loss of heterozygosity:multiple (human) |
RGD |
PMID:20126411 |
RGD:11576301 |
NCBI chrNW_004936542:4,136,389...4,235,746
Ensembl chrNW_004936542:4,136,511...4,228,288
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G |
Cblb |
Cbl proto-oncogene B |
disease_progression treatment no_association |
ISO |
DNA:SNPs: :rs2305035, rs9657904 (human) DNA:SNP,haplotype: :rs2305035(human) DNA:SNPs: :rs3772534 (human) |
RGD |
PMID:26732495 PMID:29707316 |
RGD:126925239 RGD:150540334 |
NCBI chrNW_004936701:1,157,790...1,353,375
Ensembl chrNW_004936701:1,157,797...1,353,388
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G |
Ccnb1 |
cyclin B1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34837450 |
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NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704
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G |
Ccnd1 |
cyclin D1 |
disease_progression treatment |
ISO |
DNA:amplification DNA:SNP: :870A>G (human) mRNA:splice variant |
RGD |
PMID:9462706 PMID:16406195 PMID:18715616 PMID:26055143 |
RGD:11052612 RGD:13434924 RGD:13434926 RGD:13434928 |
Ensembl chrNW_004936599:973,838...983,316
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G |
Ccnd2 |
cyclin D2 |
|
ISO |
protein:increased expression:lung mRNA:increased expression:lung |
RGD |
PMID:30227870 PMID:31253987 |
RGD:151665100 RGD:151665108 |
NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810
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G |
Ccne1 |
cyclin E1 |
disease_progression |
ISO |
|
RGD |
PMID:11212263 |
RGD:13673913 |
NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008
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G |
Ccnh |
cyclin H |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936469:5,933,163...5,952,190
Ensembl chrNW_004936469:5,935,131...5,952,460
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G |
Cd74 |
CD74 molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22919003 |
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NCBI chrNW_004936504:4,522,576...4,532,289
Ensembl chrNW_004936504:4,522,751...4,531,750
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G |
Cd9 |
CD9 molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936709:1,497,504...1,530,114
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G |
Cda |
cytidine deaminase |
|
ISO |
DNA:snp:cds:p.K27Q (human) |
RGD |
PMID:18347182 |
RGD:2316365 |
NCBI chrNW_004936474:6,543,295...6,564,575
Ensembl chrNW_004936474:6,543,220...6,566,308
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G |
Cdh13 |
cadherin 13 |
|
ISO |
DNA:hypermethylation:promoter CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:11389090 PMID:18337602 |
RGD:2293545 |
NCBI chrNW_004936641:3,925,185...4,223,421
Ensembl chrNW_004936641:3,931,033...4,224,101
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G |
Cdk4 |
cyclin dependent kinase 4 |
disease_progression treatment |
ISO |
|
RGD |
PMID:24496383 PMID:24959380 |
RGD:13464275 RGD:13464276 |
NCBI chrNW_004936646:1,886,262...1,889,260
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G |
Cdk6 |
cyclin dependent kinase 6 |
treatment |
ISO |
|
RGD |
PMID:23591808 PMID:27874949 |
RGD:13464321 RGD:13464324 |
NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
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G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
disease_progression |
ISO |
|
RGD |
PMID:9500468 |
RGD:13673920 |
NCBI chrNW_004936587:4,573,166...4,578,480
Ensembl chrNW_004936587:4,572,728...4,578,461
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Cdkn2b |
cyclin dependent kinase inhibitor 2B |
disease_progression |
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:11445839 |
RGD:13673922 |
NCBI chrNW_004936652:3,576,975...3,582,790
Ensembl chrNW_004936652:3,538,986...3,581,159
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G |
Cenpa |
centromere protein A |
severity |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:30008938 |
RGD:36947379 |
NCBI chrNW_004936493:5,715,274...5,720,816
Ensembl chrNW_004936493:5,714,782...5,720,837
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G |
Cert1 |
ceramide transporter 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936549:1,261,913...1,368,743
Ensembl chrNW_004936549:1,261,931...1,371,380
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G |
Chfr |
checkpoint with forkhead and ring finger domains |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20705357 |
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NCBI chrNW_004936660:2,725,019...2,754,564
Ensembl chrNW_004936660:2,724,989...2,754,586
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G |
Chga |
chromogranin A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21595568 |
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NCBI chrNW_004936733:915,700...927,220
Ensembl chrNW_004936733:915,830...927,409
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G |
Chi3l1 |
chitinase 3 like 1 |
severity |
ISO |
protein:increased secretion:serum (human) |
RGD |
PMID:20564116 |
RGD:4892660 |
NCBI chrNW_004936567:1,411,080...1,418,332
Ensembl chrNW_004936567:1,411,037...1,418,801
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G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
disease_progression susceptibility |
ISO |
DNA:SNP: :rs6495309(human) DNA:SNP:exon: (rs1051730) (human) |
RGD |
PMID:21747048 PMID:22722785 |
RGD:151347532 RGD:151660346 |
NCBI chrNW_004936471:36,427,598...36,447,903
Ensembl chrNW_004936471:36,427,495...36,457,758
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G |
Chrna5 |
cholinergic receptor nicotinic alpha 5 subunit |
disease_progression |
ISO |
DNA:SNP: :rs667282(human) |
RGD |
PMID:27050379 |
RGD:150527847 |
NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618
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Chrna7 |
cholinergic receptor nicotinic alpha 7 subunit |
ameliorates |
ISO |
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RGD |
PMID:19151195 PMID:19326440 |
RGD:151667906 RGD:151667908 |
NCBI chrNW_004937351:32,324...46,871
Ensembl chrNW_004937351:34,921...47,246
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G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
severity |
ISO |
|
RGD |
PMID:25172267 |
RGD:151361147 |
NCBI chrNW_004936471:36,408,471...36,425,571
Ensembl chrNW_004936471:36,408,447...36,426,021
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G |
Clptm1l |
CLPTM1 like |
no_association disease_progression |
ISO |
DNA:SNPs:: rs401681,rs4975616(human) CTD Direct Evidence: marker/mechanism DNA:SNP: :rs31490(human) DNA:SNPs: :rs4975616,rs401681(human) |
RGD CTD |
PMID:22675468 PMID:24175795 PMID:24679952 PMID:27982019 |
RGD:150530500 RGD:150530632 RGD:150530644 |
NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750
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Cmpk1 |
cytidine/uridine monophosphate kinase 1 |
severity |
ISO |
DNA:snps:intron:IVS1+1057C>A rs4492666, IVS1-928C>A rs11211524 (human) |
RGD |
PMID:21642870 |
RGD:5133252 |
NCBI chrNW_004936474:28,147,459...28,180,779
Ensembl chrNW_004936474:28,147,085...28,182,043
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G |
Col7a1 |
collagen type VII alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30381462 |
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NCBI chrNW_004936529:348,938...381,701
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G |
Coro1c |
coronin 1C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936769:555,719...637,420
Ensembl chrNW_004936769:553,642...637,008
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G |
Csf1r |
colony stimulating factor 1 receptor |
severity ameliorates |
ISO |
DNA:missense mutation:CDS:p.H362R (rs10079250) (human) mRNA,protein:increased expression:lung (human) human cells in a mouse model mRNA:decreased expression:lung (human) |
RGD |
PMID:24451080 PMID:27486763 PMID:28449811 PMID:33428598 |
RGD:150524288 RGD:150524292 RGD:150524294 RGD:150524295 |
NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
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G |
Csf3 |
colony stimulating factor 3 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:7692001 |
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NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
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G |
Cst6 |
cystatin E/M |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936599:3,541,359...3,543,206
Ensembl chrNW_004936599:3,541,272...3,543,418
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G |
Ctdspl |
CTD small phosphatase like |
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ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:22491060 |
RGD:153350086 |
NCBI chrNW_004936473:27,228,512...27,340,483
Ensembl chrNW_004936473:27,228,036...27,340,483
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G |
Cux1 |
cut like homeobox 1 |
exacerbates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:28405678 |
RGD:152985544 |
NCBI chrNW_004936543:1,482,606...1,781,294
Ensembl chrNW_004936543:1,485,970...1,796,070
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
disease_progression |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:22977534 |
RGD:152023747 |
NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118
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G |
Dab2ip |
DAB2 interacting protein |
disease_progression |
ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:31849482 |
RGD:151665206 |
NCBI chrNW_004936487:10,056,809...10,243,021
Ensembl chrNW_004936487:10,145,278...10,243,174
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G |
Dapk1 |
death associated protein kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11313923 |
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NCBI chrNW_004936680:2,842,930...3,020,757
Ensembl chrNW_004936680:2,842,547...3,021,058
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G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
disease_progression |
ISO |
|
RGD |
PMID:17299390 |
RGD:150429714 |
NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833
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G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
|
ISO |
mRNA:decreased expression:lung ClinVar Annotator: match by term: Non-small cell lung carcinoma |
RGD ClinVar |
PMID:17299390 PMID:22328973 PMID:28492532 |
RGD:150429714 |
NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139
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G |
Deup1 |
deuterosome assembly protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936674:1,334,605...1,401,943
Ensembl chrNW_004936674:1,334,605...1,401,943
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G |
Diablo |
diablo IAP-binding mitochondrial protein |
|
ISO |
mRNA:increased expression:lung |
RGD |
PMID:16231180 |
RGD:13434909 |
NCBI chrNW_004936558:2,260,459...2,268,941
Ensembl chrNW_004936558:2,260,359...2,268,941
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G |
Dnai7 |
dynein axonemal intermediate chain 7 |
ameliorates |
ISO |
|
RGD |
PMID:24860162 |
RGD:152998908 |
NCBI chrNW_004936548:2,123,248...2,197,245
Ensembl chrNW_004936548:2,123,360...2,202,032
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G |
Dnmt1 |
DNA methyltransferase 1 |
treatment |
ISO |
|
RGD |
PMID:32211850 |
RGD:126848780 |
NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416
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G |
Dusp3 |
dual specificity phosphatase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936541:325,443...338,426
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G |
E2f1 |
E2F transcription factor 1 |
treatment severity disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12237873 PMID:12358350 PMID:23543735 PMID:28498400 PMID:29754146 |
RGD:13464333 RGD:13464342 RGD:13464343 RGD:9590260 |
NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026
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G |
E2f2 |
E2F transcription factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29754146 |
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NCBI chrNW_004936474:8,719,243...8,739,811
Ensembl chrNW_004936474:8,719,253...8,737,763
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G |
E2f3 |
E2F transcription factor 3 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNP: :rs3806116 (human) |
CTD RGD |
PMID:27557513 PMID:29754146 |
RGD:13464345 |
NCBI chrNW_004936552:5,712,247...5,783,643
Ensembl chrNW_004936552:5,711,923...5,783,694
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G |
E2f5 |
E2F transcription factor 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29754146 |
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NCBI chrNW_004936544:124,243...153,325
Ensembl chrNW_004936544:125,360...152,670
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G |
E2f6 |
E2F transcription factor 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29754146 |
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NCBI chrNW_004936532:7,356,525...7,375,173
Ensembl chrNW_004936532:7,356,510...7,375,536
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G |
E2f7 |
E2F transcription factor 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29754146 |
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NCBI chrNW_004936568:5,206,135...5,245,324
Ensembl chrNW_004936568:5,206,135...5,244,450
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G |
E2f8 |
E2F transcription factor 8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29754146 |
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NCBI chrNW_004936654:322,863...339,365
Ensembl chrNW_004936654:322,863...338,699
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
disease_progression |
ISO |
protein:increased expression:blood serum (human) |
RGD |
PMID:24377563 |
RGD:153298905 |
NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609
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G |
Egf |
epidermal growth factor |
treatment |
ISO |
|
RGD |
PMID:25992884 PMID:26927662 |
RGD:13464348 RGD:13464350 |
NCBI chrNW_004936563:1,058,803...1,181,393
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G |
Egfr |
epidermal growth factor receptor |
severity ameliorates treatment susceptibility |
ISO |
ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma | ClinVar Annotator: match by term: Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somatic human cells in mouse model protein:decreased expression:tumor (human) |
RGD ClinVar |
PMID:11423618 PMID:11789762 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 PMID:15604253 PMID:15623594 PMID:15625347 PMID:15710947 PMID:15728811 PMID:15737014 PMID:15738541 PMID:15741570 PMID:15788655 PMID:15897572 PMID:15901872 PMID:15998907 PMID:16105816 PMID:16115929 PMID:16187797 PMID:16199108 PMID:16203769 PMID:16204011 PMID:16205628 PMID:16258541 PMID:16467085 PMID:16533793 PMID:16863509 PMID:16865253 PMID:16912157 PMID:16956694 PMID:17020982 PMID:17047654 PMID:17085664 PMID:17106442 PMID:17192902 PMID:17285735 PMID:17317677 PMID:17387341 PMID:17429313 PMID:17473653 PMID:17473659 PMID:17510392 PMID:17726540 PMID:17904685 PMID:18093943 PMID:18176089 PMID:18227510 PMID:18325048 PMID:18334834 PMID:18372921 PMID:18450321 PMID:18596266 PMID:18948947 PMID:18981003 PMID:18992959 PMID:19096302 PMID:19096324 PMID:19381876 PMID:19536777 PMID:19589612 PMID:19692680 PMID:20022809 PMID:20033049 PMID:20038723 PMID:20068085 PMID:20129249 PMID:20479403 PMID:20522446 PMID:20559149 PMID:20573926 PMID:20808254 PMID:21057810 PMID:21124077 PMID:21233402 PMID:21248300 PMID:21252721 PMID:21317742 PMID:21430269 PMID:21527506 PMID:21531810 PMID:21572125 PMID:21592614 PMID:21841502 PMID:21899495 PMID:21900837 PMID:21921847 PMID:22019513 PMID:22215752 PMID:22370314 PMID:22588155 PMID:22760226 PMID:22809298 PMID:22992668 PMID:23468066 PMID:23540867 PMID:24033266 PMID:24039832 PMID:24202392 PMID:24453288 PMID:24478319 PMID:24712396 PMID:24736066 PMID:24736080 PMID:25061320 PMID:25521405 PMID:25741868 PMID:26051236 PMID:26490356 PMID:26700910 PMID:27040853 PMID:27993330 PMID:28492532 PMID:28947568 PMID:29100434 PMID:29141884 PMID:30610926 PMID:31205511 PMID:31396478 PMID:32276600 PMID:33858029 More...
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RGD:126790479 RGD:13464349 RGD:151357000 RGD:153344584 RGD:5131640 |
NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
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Egr1 |
early growth response 1 |
resistance |
ISO |
mRNA:increased expression:tumor (human) |
RGD |
PMID:15774784 |
RGD:5131925 |
NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936710:1,446,030...1,461,945
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G |
Eml4 |
EMAP like 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17625570 PMID:21757253 PMID:21767331 PMID:22568572 PMID:22617245 PMID:22986231 More...
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NCBI chrNW_004936508:9,303,639...9,447,478
Ensembl chrNW_004936508:9,303,639...9,447,548
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G |
Eno1 |
enolase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183
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G |
Eno2 |
enolase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21595568 |
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NCBI chrNW_004936709:904,647...913,445
Ensembl chrNW_004936709:904,031...913,451
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G |
Epas1 |
endothelial PAS domain protein 1 |
treatment |
ISO |
|
RGD |
PMID:21812995 |
RGD:10395382 |
NCBI chrNW_004936508:5,855,748...5,938,879
Ensembl chrNW_004936508:5,855,732...5,938,856
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Ephx1 |
epoxide hydrolase 1 |
disease_progression |
ISO |
|
RGD |
PMID:17273734 |
RGD:4889124 |
NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
|
ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:15457249 PMID:15753357 PMID:16638863 PMID:16863509 PMID:18334834 PMID:22325357 PMID:22761469 PMID:24033266 More...
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NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
disease_progression treatment |
ISO |
|
RGD |
PMID:11789762 PMID:20364069 |
RGD:126790478 RGD:126790479 |
NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
disease_progression treatment severity |
ISO |
DNA:SNPs:multiple (human) protein:decreased expression:lung (human) CTD Direct Evidence: marker/mechanism DNA:silent mutation:cds:p.N118N (human) |
RGD CTD |
PMID:15140544 PMID:16957145 PMID:21553054 PMID:23549037 PMID:23912706 PMID:24443257 PMID:28924235 More...
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RGD:127229948 RGD:127229950 RGD:13207308 RGD:13207428 RGD:153323316 |
NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
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G |
Ercc2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
disease_progression treatment |
ISO |
DNA:polymorphism:cds:p.K751Q(human) DNA:SNPs:multiple (human) |
RGD |
PMID:25596702 PMID:28924235 |
RGD:12880391 RGD:153323316 |
NCBI chrNW_004936706:1,816,561...1,829,638
Ensembl chrNW_004936706:1,816,571...1,829,692
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G |
Ercc3 |
ERCC excision repair 3, TFIIH core complex helicase subunit |
treatment |
ISO |
DNA:snp:intron:c.2064+741T>C (rs3738948) (human) |
RGD |
PMID:25069034 |
RGD:11098167 |
NCBI chrNW_004936469:43,970,002...43,998,279
Ensembl chrNW_004936469:43,969,740...43,998,448
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G |
Ercc5 |
ERCC excision repair 5, endonuclease |
treatment |
ISO |
DNA:SNPs:multiple (human) |
RGD |
PMID:24782167 PMID:28924235 |
RGD:151347410 RGD:153323316 |
NCBI chrNW_004936472:8,209,482...8,234,696
Ensembl chrNW_004936472:8,209,540...8,234,334
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G |
Ercc6 |
ERCC excision repair 6, chromatin remodeling factor |
treatment |
ISO |
DNA:SNP:intron: (rs4253002) (human) |
RGD |
PMID:28924235 |
RGD:153323316 |
NCBI chrNW_004936728:706,499...843,447
Ensembl chrNW_004936728:761,804...844,690
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G |
Ergic3 |
ERGIC and golgi 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27588471 |
|
NCBI chrNW_004936561:5,256,450...5,270,073
Ensembl chrNW_004936561:5,256,417...5,270,344
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G |
Esr1 |
estrogen receptor 1 |
|
ISO |
DNA:hypermethylation: :lung |
RGD |
PMID:19506903 |
RGD:4892255 |
NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
disease_progression |
ISO |
|
RGD |
PMID:21539681 PMID:23300840 |
RGD:126781700 RGD:126781715 |
NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939
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G |
Fap |
fibroblast activation protein alpha |
disease_progression |
ISO |
|
RGD |
PMID:29415055 |
RGD:152600902 |
NCBI chrNW_004936469:16,817,000...16,889,066
Ensembl chrNW_004936469:16,817,232...16,888,773
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G |
Faslg |
Fas ligand |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21807637 |
|
NCBI chrNW_004936481:14,789,547...14,795,780
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G |
Fat1 |
FAT atypical cadherin 1 |
treatment |
ISO |
CTD Direct Evidence: therapeutic |
RGD CTD |
PMID:31085721 PMID:34390292 |
RGD:151347689 |
NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823
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Fbxo11 |
F-box protein 11 |
treatment |
ISO |
|
RGD |
PMID:31778188 |
RGD:152025265 |
NCBI chrNW_004936508:4,622,695...4,708,694
Ensembl chrNW_004936508:4,685,595...4,708,694
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G |
Fgf9 |
fibroblast growth factor 9 |
severity |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung (human) |
CTD RGD |
PMID:19358281 PMID:24239165 PMID:31884893 |
RGD:152177524 RGD:152177912 |
NCBI chrNW_004936720:282,291...316,629
Ensembl chrNW_004936720:279,521...316,674
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Fgfr1 |
fibroblast growth factor receptor 1 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:22286583 PMID:23806793 PMID:27794399 |
RGD:25330355 |
NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
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G |
Fgfr4 |
fibroblast growth factor receptor 4 |
severity disease_progression |
ISO |
DNA:SNP:exon 9: p.G3888R (rs351855) (human) mRNA, protein:increased expression:lung (human) |
RGD |
PMID:23524567 PMID:26045670 |
RGD:150429970 RGD:150429982 |
NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
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Fh |
fumarate hydratase |
severity |
ISO |
DNA:SNP: (rs1414493) (human) |
RGD |
PMID:25576295 |
RGD:150340558 |
NCBI chrNW_004936526:8,936,096...8,965,155
Ensembl chrNW_004936526:8,935,991...8,965,367
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Fhit |
fragile histidine triad diadenosine triphosphatase |
disease_progression |
ISO |
DNA:loss of heterozygosity:intron: CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:9635574 PMID:9850082 PMID:11788890 |
RGD:13792770 RGD:13792815 |
NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506
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Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
disease_progression |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:25375657 |
RGD:11074609 |
NCBI chrNW_004936493:4,308,683...4,327,102
Ensembl chrNW_004936493:4,304,395...4,327,179
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G |
Foxa1 |
forkhead box A1 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung |
CTD RGD |
PMID:26658322 PMID:26909612 PMID:32717239 |
RGD:11554787 RGD:151665747 |
NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
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Foxa2 |
forkhead box A2 |
|
ISO |
mRNA:decreased expression:lung |
RGD |
PMID:26658322 |
RGD:11554787 |
NCBI chrNW_004936620:2,966,341...2,969,349
Ensembl chrNW_004936620:2,966,341...2,969,349
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Foxl2 |
forkhead box L2 |
|
ISO |
DNA:hypermethylation: (human) |
RGD |
PMID:23599765 |
RGD:13503323 |
NCBI chrNW_004936540:1,136,403...1,137,984
Ensembl chrNW_004936540:1,136,468...1,137,574
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Foxm1 |
forkhead box M1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18345025 PMID:19672312 |
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NCBI chrNW_004936606:3,185,289...3,198,427
Ensembl chrNW_004936606:3,185,982...3,198,378
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G |
Foxo3 |
forkhead box O3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19380174 |
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NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837
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G |
Foxp1 |
forkhead box P1 |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:22491060 |
RGD:153350086 |
NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
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Frzb |
frizzled related protein |
|
ISO |
DNA:hypermethylation:exon 1 |
RGD |
PMID:27623992 |
RGD:32716395 |
NCBI chrNW_004936509:11,440,414...11,471,042
Ensembl chrNW_004936509:11,440,148...11,470,967
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Gclc |
glutamate-cysteine ligase catalytic subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936476:7,371,270...7,418,756
Ensembl chrNW_004936476:7,371,149...7,418,958
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Gipr |
gastric inhibitory polypeptide receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936706:2,052,069...2,062,722
Ensembl chrNW_004936706:2,053,433...2,061,241
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Gpr135 |
G protein-coupled receptor 135 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28722770 |
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NCBI chrNW_004936495:3,812,825...3,814,252
Ensembl chrNW_004936495:3,813,078...3,814,256
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G |
Gpx1 |
glutathione peroxidase 1 |
onset treatment |
ISO |
mRNA:increased expression:leukocyte (human) DNA:SNP: (human) |
RGD |
PMID:19347979 PMID:33474835 |
RGD:152998881 RGD:152998904 |
NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987
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Grik2 |
glutamate ionotropic receptor kainate type subunit 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936651:2,756,559...3,401,806
Ensembl chrNW_004936651:2,762,380...3,401,808
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G |
Grp |
gastrin releasing peptide |
disease_progression |
ISO |
protein:increased expression:serum (human) |
RGD |
PMID:30146822 |
RGD:401700396 |
NCBI chrNW_004936497:5,473,293...5,487,344
Ensembl chrNW_004936497:5,476,800...5,487,358
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G |
Gstp1 |
glutathione S-transferase pi 1 |
susceptibility |
ISO |
DNA:SNP: :p.A114V (human) CTD Direct Evidence: marker/mechanism DNA:polymorphism:exon:p.I105V (human) |
RGD CTD |
PMID:17094902 PMID:18258609 PMID:19174490 |
RGD:4140944 RGD:4140950 |
NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050
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Hdac3 |
histone deacetylase 3 |
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ISO |
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RGD |
PMID:24482232 |
RGD:9588265 |
NCBI chrNW_004936504:12,530,546...12,546,556
Ensembl chrNW_004936504:12,530,528...12,546,556
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G |
Hes1 |
hes family bHLH transcription factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21994468 |
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NCBI chrNW_004936711:640,002...642,580
Ensembl chrNW_004936711:639,905...642,622
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:21812995 PMID:30381462 |
RGD:10395382 |
NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
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ISO |
protein:increased expression:lung (human) |
RGD |
PMID:20716340 |
RGD:9999189 |
NCBI chrNW_004936512:11,481,017...11,487,737
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Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
susceptibility |
ISO |
antibody 703D4 recognizes Hnrnpa2b1 protein (RGD:9685415);protein:increased expression:sputum (human) |
RGD |
PMID:2846790 |
RGD:9685413 |
NCBI chrNW_004936478:2,970,261...2,980,277
Ensembl chrNW_004936478:2,970,468...2,980,381
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G |
Hras |
HRas proto-oncogene, GTPase |
|
ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 PMID:6287573 PMID:6288698 PMID:10716188 PMID:21779495 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29493581 More...
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NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
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G |
Hs3st2 |
heparan sulfate-glucosamine 3-sulfotransferase 2 |
|
ISO |
DNA:hypermethylation |
RGD |
PMID:27777637 |
RGD:152998954 |
NCBI chrNW_004936501:7,645,007...7,729,313
Ensembl chrNW_004936501:7,644,619...7,729,323
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G |
Htra1 |
HtrA serine peptidase 1 |
exacerbates |
ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:32878625 |
RGD:152975629 |
NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739
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G |
Icam1 |
intercellular adhesion molecule 1 |
disease_progression |
ISO |
progression-free survival; protein:increased secretion:serum (human) |
RGD |
PMID:19949019 |
RGD:4145465 |
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
severity |
ISO |
DNA:SNP: (rs11540478) (human) |
RGD |
PMID:25576295 |
RGD:150340558 |
NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
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G |
Ikzf2 |
IKAROS family zinc finger 2 |
exacerbates |
ISO |
protein:decreased expression:venous blood, lung, regulatory T cell (human) |
RGD |
PMID:26460798 |
RGD:151347635 |
NCBI chrNW_004936586:3,522,614...3,676,070
Ensembl chrNW_004936586:3,525,933...3,674,061
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G |
Ikzf3 |
IKAROS family zinc finger 3 |
exacerbates |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:24823637 |
RGD:151347636 |
NCBI chrNW_004936490:14,939,693...15,025,728
Ensembl chrNW_004936490:14,939,776...15,025,728
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Il10 |
interleukin 10 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20471133 |
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NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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G |
Il18 |
interleukin 18 |
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ISO |
protein:increased expression:serum |
RGD |
PMID:15955140 |
RGD:4889836 |
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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G |
Il1a |
interleukin 1 alpha |
|
ISO |
DNA:SNPs: : |
RGD |
PMID:19505916 |
RGD:4142793 |
NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
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G |
Il1b |
interleukin 1 beta |
susceptibility |
ISO |
DNA:polymorphism: :-31T>C (human) |
RGD |
PMID:16126303 |
RGD:4143167 |
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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G |
Il1rn |
interleukin 1 receptor antagonist |
susceptibility |
ISO |
DNA:polymorphism (human) |
RGD |
PMID:16126303 |
RGD:4143167 |
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
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G |
Il6r |
interleukin 6 receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22552503 |
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NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885
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G |
Il7 |
interleukin 7 |
disease_progression |
ISO |
|
RGD |
PMID:21159243 |
RGD:151347686 |
NCBI chrNW_004936702:110,625...162,957
Ensembl chrNW_004936702:111,211...162,322
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G |
Il7r |
interleukin 7 receptor |
susceptibility disease_progression |
ISO |
DNA:SNPs:: rs1494555,rs7737000(human) |
RGD |
PMID:19505916 PMID:21159243 |
RGD:151347686 RGD:4142793 |
NCBI chrNW_004936518:5,815,820...5,842,571
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Iqsec1 |
IQ motif and Sec7 domain ArfGEF 1 |
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ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:22491060 |
RGD:153350086 |
NCBI chrNW_004936898:318,564...425,785
Ensembl chrNW_004936898:337,400...425,859
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G |
Irf1 |
interferon regulatory factor 1 |
|
ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:10395927 |
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NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636
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G |
Irs4 |
insulin receptor substrate 4 |
|
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:33894221 |
RGD:151347872 |
NCBI chrNW_004936499:6,111,422...6,127,487
Ensembl chrNW_004936499:6,111,487...6,115,272
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G |
Itga9 |
integrin subunit alpha 9 |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:22491060 |
RGD:153350086 |
NCBI chrNW_004936473:26,875,337...27,188,747
Ensembl chrNW_004936473:26,876,671...27,184,795
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G |
Itgb1 |
integrin subunit beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung |
CTD RGD |
PMID:21478906 PMID:28537888 |
RGD:13792830 |
NCBI chrNW_004936574:1,465,981...1,495,717
Ensembl chrNW_004936574:1,465,897...1,495,762
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Itgb3 |
integrin subunit beta 3 |
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ISO |
|
RGD |
PMID:19386436 |
RGD:5037228 |
NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035
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G |
Itgb4 |
integrin subunit beta 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27107458 |
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NCBI chrNW_004936594:912,302...944,819
Ensembl chrNW_004936594:912,291...946,012
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G |
Jak1 |
Janus kinase 1 |
disease_progression |
ISO |
protein:increased phosphorylation:lung |
RGD |
PMID:28989534 |
RGD:150524360 |
NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132
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G |
Jak2 |
Janus kinase 2 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:21325979 PMID:25869210 |
RGD:149735332 RGD:149735342 |
NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
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Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
severity |
ISO |
RNA:increased expression:lung (human) |
RGD |
PMID:29895215 |
RGD:151347665 |
NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123
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G |
Kat2a |
lysine acetyltransferase 2A |
disease_progression |
ISO |
|
RGD |
PMID:23543735 |
RGD:9590260 |
NCBI chrNW_004936490:16,952,698...16,960,424
Ensembl chrNW_004936490:16,952,363...16,960,489
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G |
Kdm1a |
lysine demethylase 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22493729 |
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NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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G |
Kdm2a |
lysine demethylase 2A |
severity |
ISO |
mRNA:increased expression:stomach (human) human gene in a mouse model |
RGD |
PMID:24200691 PMID:24482232 |
RGD:9588263 RGD:9588265 |
NCBI chrNW_004936599:2,466,427...2,576,623
Ensembl chrNW_004936599:2,466,214...2,576,623
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G |
Kdm3b |
lysine demethylase 3B |
|
ISO |
DNA:amplification:lung, peripheral blood mononuclear cell (human) |
RGD |
PMID:18975135 |
RGD:9586737 |
NCBI chrNW_004936531:7,517,810...7,600,319
Ensembl chrNW_004936531:7,516,125...7,600,347
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G |
Kdm5a |
lysine demethylase 5A |
severity |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:25162518 |
RGD:9588530 |
NCBI chrNW_004936606:486,424...570,546
Ensembl chrNW_004936606:485,655...570,739
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G |
Kdm6a |
lysine demethylase 6A |
exacerbates |
ISO |
human cells in a mouse model |
RGD |
PMID:32879445 |
RGD:150429731 |
NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
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G |
Kdr |
kinase insert domain receptor |
disease_progression treatment |
ISO |
DNA:CNVs DNA:SNP:promoter:���906T>C (rs2071559) (human) DNA, protein:CNVs, increased expression:lung protein:increased expression:plasma |
RGD |
PMID:12415261 PMID:16697074 PMID:21481963 PMID:21724587 PMID:25561764 PMID:25975224 More...
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RGD:126908001 RGD:126925188 RGD:126925189 RGD:126925192 RGD:126925198 RGD:126925199 |
NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002
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G |
Keap1 |
kelch like ECH associated protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22684020 |
|
NCBI chrNW_004936659:785,059...793,775
Ensembl chrNW_004936659:782,340...793,688
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G |
Kif5b |
kinesin family member 5B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21757253 |
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NCBI chrNW_004936574:780,074...823,858
Ensembl chrNW_004936574:779,777...823,970
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G |
Kit |
KIT proto-oncogene, receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24688052 |
|
NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274
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G |
Kmt2c |
lysine methyltransferase 2C |
disease_progression |
ISO |
|
RGD |
PMID:33665490 |
RGD:150523771 |
NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365
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G |
Kmt2d |
lysine methyltransferase 2D |
disease_progression |
ISO |
DNA, protein:missense mutations, nonsense mutations, frameshift mutation, increased expression:lung |
RGD |
PMID:25112956 PMID:29627316 PMID:33665490 |
RGD:150523767 RGD:150523769 RGD:150523771 |
NCBI chrNW_004936512:6,819,240...6,860,852
Ensembl chrNW_004936512:6,822,057...6,854,451
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G |
Kras |
KRAS proto-oncogene, GTPase |
|
ISO |
ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:2547513 PMID:3627975 PMID:6320174 PMID:6695174 PMID:7773929 PMID:8439212 PMID:11745231 PMID:12720172 PMID:15093544 PMID:15696205 PMID:15842656 PMID:16051643 PMID:16247081 PMID:16474404 PMID:16474405 PMID:17062680 PMID:17332249 PMID:17704260 PMID:17910045 PMID:19047918 PMID:19349489 PMID:19358724 PMID:19396835 PMID:19794967 PMID:20805368 PMID:20926413 PMID:20949522 PMID:20949621 PMID:21044336 PMID:21063026 PMID:21079152 PMID:21169357 PMID:22499344 PMID:22571758 PMID:22683711 PMID:23096712 PMID:23255105 PMID:23548132 PMID:24033266 PMID:24138715 PMID:24382853 PMID:24720724 PMID:25695684 PMID:25705018 PMID:25741868 PMID:25808193 PMID:26242988 PMID:26521233 PMID:27577878 PMID:28492532 PMID:29298116 PMID:29493581 PMID:30443000 PMID:30544177 PMID:30732632 PMID:30902772 PMID:31573083 PMID:31666701 PMID:31891627 PMID:32581362 PMID:33142350 PMID:34114335 PMID:34958143 PMID:35658005 PMID:35794233 More...
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NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
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L1cam |
L1 cell adhesion molecule |
disease_progression |
ISO |
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RGD |
PMID:22307136 |
RGD:11570503 |
NCBI chrNW_004936809:736,385...768,822
Ensembl chrNW_004936809:736,319...761,973
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Lamb3 |
laminin subunit beta 3 |
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ISO |
mRNA:increased expression:lung: |
RGD |
PMID:10964684 |
RGD:13793368 |
NCBI chrNW_004936557:3,429,488...3,487,995
Ensembl chrNW_004936557:3,450,247...3,487,954
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Lamc2 |
laminin subunit gamma 2 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung: |
RGD CTD |
PMID:10964684 PMID:26180921 PMID:30381462 |
RGD:13793367 RGD:13793368 |
NCBI chrNW_004936481:6,588,797...6,647,167
Ensembl chrNW_004936481:6,588,865...6,647,188
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Lep |
leptin |
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ISO |
protein:increased expression:serum |
RGD |
PMID:19033693 |
RGD:5128815 |
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
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Lgals1 |
galectin 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936492:3,407,704...3,411,197
Ensembl chrNW_004936492:3,407,049...3,411,222
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LOC101954516 |
signal transducer and activator of transcription 5B |
disease_progression |
ISO |
mRNA,protein:increased expression:lung (human) |
RGD |
PMID:25137041 |
RGD:153298930 |
NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941
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LOC101957714 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
susceptibility disease_progression exacerbates |
ISO |
DNA:SNPs:multiple (human) DNA:SNP:exon, intron: (rs6068816, rs2181874) (human) DNA:SNP:intron 4: (rs3787554) (human) mRNA:increased expression:lung (human) DNA:SNPs:CDS, 3' utr: (rs6068816, rs4809957) (human) |
RGD |
PMID:17671213 PMID:21169243 PMID:23435876 PMID:25544771 PMID:27669215 PMID:29250167 PMID:29726119 More...
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RGD:151361179 RGD:151361182 RGD:151361185 RGD:151665175 RGD:151665789 RGD:151708738 RGD:151708739 |
NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
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LOC101964975 |
interleukin-8 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15956251 |
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NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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LOC101971998 |
guanine nucleotide-binding protein G(q) subunit alpha |
disease_progression |
ISO |
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RGD |
PMID:24518087 |
RGD:126781753 |
NCBI chrNW_004936503:13,098,517...13,276,106
Ensembl chrNW_004936503:13,099,558...13,276,152
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LOC101973029 |
cytochrome P450 2E1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16142352 |
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NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102
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Lrp1b |
LDL receptor related protein 1B |
ameliorates |
ISO |
DNA:mutations:multiple: (human) |
RGD |
PMID:31164891 |
RGD:150429775 |
NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283
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Lrrc56 |
leucine rich repeat containing 56 |
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ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 PMID:6287573 PMID:6288698 PMID:10716188 PMID:21779495 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29493581 More...
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NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
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Lrrc59 |
leucine rich repeat containing 59 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936490:11,296,590...11,308,379
Ensembl chrNW_004936490:11,296,530...11,310,946
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Lta |
lymphotoxin alpha |
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ISO |
protein:increased expression:lung |
RGD |
PMID:9669810 |
RGD:4143264 |
NCBI chrNW_004936727:1,940,081...1,941,022
Ensembl chrNW_004936727:1,940,081...1,941,022
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Ltf |
lactotransferrin |
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ISO |
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RGD |
PMID:21532506 |
RGD:7243860 |
NCBI chrNW_004936596:344,287...373,788
Ensembl chrNW_004936596:344,274...373,952
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Macir |
macrophage immunometabolism regulator |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936523:1,273,812...1,292,837
Ensembl chrNW_004936523:1,275,214...1,292,854
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Manf |
mesencephalic astrocyte derived neurotrophic factor |
susceptibility |
ISO |
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RGD |
PMID:8971156 |
RGD:1599219 |
NCBI chrNW_004936529:2,774,651...2,777,960
Ensembl chrNW_004936529:2,774,543...2,779,579
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Map2k1 |
mitogen-activated protein kinase kinase 1 |
ameliorates |
ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma |
RGD ClinVar |
PMID:7651428 PMID:17704260 PMID:18060073 PMID:18632602 PMID:19411838 PMID:19915144 PMID:20301365 PMID:21514245 PMID:22327936 PMID:23444215 PMID:23569304 PMID:24033266 PMID:25049390 PMID:25157968 PMID:25741868 PMID:28492532 PMID:29643386 PMID:30763456 More...
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RGD:150530476 |
NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302
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Map2k2 |
mitogen-activated protein kinase kinase 2 |
ameliorates |
ISO |
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RGD |
PMID:21514245 |
RGD:150530476 |
NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090
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Map2k4 |
mitogen-activated protein kinase kinase 4 |
ameliorates |
ISO |
associated with Postoperative Complications;DNA:SNP:intron: (rs12452497)(human) |
RGD |
PMID:26165383 |
RGD:11521299 |
NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662
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Map2k7 |
mitogen-activated protein kinase kinase 7 |
exacerbates susceptibility |
ISO |
DNA:SNP:3' utr: (rs3679) (human) |
RGD |
PMID:21317887 PMID:27861856 |
RGD:155230827 RGD:155249848 |
NCBI chrNW_004936588:4,882,191...4,891,807
Ensembl chrNW_004936588:4,882,184...4,892,071
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Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
severity |
ISO |
DNA:SNPs:5'-UTR, intron 1: (rs17661089, rs16886403, rs726501) (human) |
RGD |
PMID:21636554 |
RGD:150573805 |
NCBI chrNW_004936480:11,082,811...11,156,691
Ensembl chrNW_004936480:11,083,605...11,156,691
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Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
disease_progression |
ISO |
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RGD |
PMID:23533274 PMID:28393206 |
RGD:151356965 RGD:151356978 |
NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892
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Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
ameliorates disease_progression severity |
ISO |
human cells in mouse model protein:increased expression:lung, cytoplasm (human) DNA:mutations:multiple protein:increased expression:lung (human) |
RGD |
PMID:24469836 PMID:27264345 PMID:29567880 PMID:31662324 PMID:32276600 PMID:32945371 More...
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RGD:151356750 RGD:151356758 RGD:151356906 RGD:151356915 RGD:151356931 RGD:151357000 |
NCBI chrNW_004936580:803,452...806,966
Ensembl chrNW_004936580:804,903...806,796
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Mdm2 |
MDM2 proto-oncogene |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19941079 PMID:21268124 |
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NCBI chrNW_004936545:6,709,903...6,732,334
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Meox1 |
mesenchyme homeobox 1 |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:34837450 |
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NCBI chrNW_004936541:216,390...238,153
Ensembl chrNW_004936541:217,193...236,031
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Met |
MET proto-oncogene, receptor tyrosine kinase |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:21623265 PMID:21815704 PMID:22787409 PMID:24092988 PMID:24688052 |
RGD:13434906 |
NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179
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Mier3 |
MIER family member 3 |
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ISO |
mRNA:decreased expression:lung |
RGD |
PMID:35117188 |
RGD:407571696 |
NCBI chrNW_004936480:11,001,964...11,031,891
Ensembl chrNW_004936480:11,002,583...11,032,329
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Mif |
macrophage migration inhibitory factor |
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ISO |
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RGD |
PMID:12576459 |
RGD:4891022 |
NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442
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Mki67 |
marker of proliferation Ki-67 |
ameliorates |
ISO |
human cells in mouse model |
RGD |
PMID:31205511 PMID:32276600 |
RGD:151357000 RGD:153344584 |
NCBI chrNW_004936486:15,561,327...15,587,109
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Mlh1 |
mutL homolog 1 |
severity |
ISO |
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RGD |
PMID:18370958 PMID:32211850 |
RGD:126848780 RGD:126848801 |
NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
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Mmp1 |
matrix metallopeptidase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20471133 |
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NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857
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Mmp11 |
matrix metallopeptidase 11 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:10741738 |
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NCBI chrNW_004936619:1,309,013...1,320,062
Ensembl chrNW_004936619:1,310,846...1,320,062
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Mmp2 |
matrix metallopeptidase 2 |
severity |
ISO |
protein:increased expression, increased activity:lung |
RGD |
PMID:17143501 |
RGD:5130739 |
NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851
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Mmp7 |
matrix metallopeptidase 7 |
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ISO |
mRNA:increased expression:lung |
RGD |
PMID:19596921 |
RGD:5129528 |
NCBI chrNW_004936551:5,388,456...5,395,071
Ensembl chrNW_004936551:5,388,459...5,395,071
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Mmp9 |
matrix metallopeptidase 9 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:serum |
CTD RGD |
PMID:20704821 PMID:21789004 |
RGD:5129215 |
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
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Ms4a1 |
membrane spanning 4-domains A1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22514692 |
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NCBI chrNW_004936581:2,466,294...2,477,530
Ensembl chrNW_004936581:2,466,312...2,477,530
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Msh2 |
mutS homolog 2 |
treatment |
ISO |
DNA:SNP: :rs6544991 (human) protein:decreased expression:lung |
RGD |
PMID:16783774 PMID:20145178 PMID:20458443 PMID:28093084 PMID:32211850 |
RGD:126848780 RGD:126848786 RGD:126848789 RGD:126848791 RGD:126848800 |
NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
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Msh3 |
mutS homolog 3 |
treatment |
ISO |
DNA:SNPs: :rs6151627, rs6151670, rs7709909 (human) |
RGD |
PMID:28093084 |
RGD:126848786 |
NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561
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Msh5 |
mutS homolog 5 |
treatment |
ISO |
DNA:SNPs: :rs805304, rs707939 (human) |
RGD |
PMID:28093084 |
RGD:126848786 |
NCBI chrNW_004936727:1,776,038...1,794,152
Ensembl chrNW_004936727:1,777,570...1,793,711
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Mt3 |
metallothionein 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936475:8,864,512...8,866,516
Ensembl chrNW_004936475:8,864,675...8,866,506
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Mtor |
mechanistic target of rapamycin kinase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342
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Mxra5 |
matrix remodeling associated 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22696596 |
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NCBI chrNW_004936644:2,502,334...2,528,278
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Myc |
MYC proto-oncogene, bHLH transcription factor |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24688052 |
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NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965
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Myd88 |
MYD88 innate immune signal transduction adaptor |
disease_progression |
ISO |
protein:increased expression:lung (human) DNA:hypomethylation:promoter (human) |
RGD |
PMID:31432177 PMID:32010578 |
RGD:150519919 RGD:150524328 |
NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
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Ncaph |
non-SMC condensin I complex subunit H |
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ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:32945371 |
RGD:151356931 |
NCBI chrNW_004936744:440,958...468,964
Ensembl chrNW_004936744:440,956...468,972
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Ncoa2 |
nuclear receptor coactivator 2 |
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ISO |
DNA:SNPs:introns: (rs2926702, rs11993276) (human) |
RGD |
PMID:23144319 |
RGD:153002581 |
NCBI chrNW_004936496:14,844,923...15,102,922
Ensembl chrNW_004936496:14,844,855...15,016,454
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Ncoa3 |
nuclear receptor coactivator 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20852035 |
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NCBI chrNW_004936514:5,900,135...5,967,862
Ensembl chrNW_004936514:5,901,601...5,967,865
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Ndc80 |
NDC80 kinetochore complex component |
disease_progression |
ISO |
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RGD |
PMID:17079454 |
RGD:28867236 |
NCBI chrNW_004936672:1,872,205...1,910,956
Ensembl chrNW_004936672:1,872,193...1,909,675
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Ndrg1 |
N-myc downstream regulated 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15341671 |
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NCBI chrNW_004936470:16,051,291...16,102,563
Ensembl chrNW_004936470:16,051,015...16,102,585
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Nek2 |
NIMA related kinase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28509438 |
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NCBI chrNW_004936557:1,683,027...1,695,410
Ensembl chrNW_004936557:1,682,984...1,695,414
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Nf1 |
neurofibromin 1 |
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ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:30280776 |
RGD:126925764 |
NCBI chrNW_004936538:3,394,623...3,596,025
Ensembl chrNW_004936538:3,398,222...3,595,261
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Nf2 |
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor |
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ISO |
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RGD |
PMID:21743150 |
RGD:150530639 |
NCBI chrNW_004936657:3,536,212...3,622,999
Ensembl chrNW_004936657:3,536,141...3,623,821
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22684020 PMID:26482881 PMID:33148531 |
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NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
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Nfkb1 |
nuclear factor kappa B subunit 1 |
susceptibility |
ISO |
DNA:polymorphism:rs28362491(human) protein:increased expression:nucleus |
RGD |
PMID:17899287 PMID:26221384 |
RGD:13793390 RGD:13793391 |
NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435
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Nnat |
neuronatin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936561:3,739,664...3,744,015
Ensembl chrNW_004936561:3,739,664...3,742,154
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Notch3 |
notch receptor 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21994468 |
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NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429
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Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
disease_progression |
ISO |
DNA:polymorphism:cds: 609 C>T (human) DNA:polymorphism: : CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:9865924 PMID:19596483 PMID:21479364 |
RGD:5133265 RGD:5133268 |
NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311
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Nr3c1 |
nuclear receptor subfamily 3 group C member 1 |
disease_progression |
ISO |
protein:increased expression:lung |
RGD |
PMID:16806572 |
RGD:4892333 |
NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856
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Nras |
NRAS proto-oncogene, GTPase |
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ISO |
ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:1654209 PMID:6587382 PMID:12727991 PMID:14508525 PMID:18633438 PMID:19880792 PMID:22499344 PMID:22773810 PMID:23392294 PMID:24006476 PMID:24033266 PMID:25741868 More...
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NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590
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Nrp1 |
neuropilin 1 |
disease_progression |
ISO |
DNA, protein:CNVs, increased expression:lung |
RGD |
PMID:25561764 |
RGD:126925188 |
NCBI chrNW_004936574:1,694,433...1,834,720
Ensembl chrNW_004936574:1,694,336...1,834,720
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Nsd2 |
nuclear receptor binding SET domain protein 2 |
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ISO |
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RGD |
PMID:34551195 |
RGD:155663369 |
NCBI chrNW_004936477:21,460,442...21,531,563
Ensembl chrNW_004936477:21,460,478...21,534,909
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Nuf2 |
NUF2 component of NDC80 kinetochore complex |
disease_progression |
ISO |
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RGD |
PMID:17079454 |
RGD:28867236 |
NCBI chrNW_004936481:21,342,667...21,371,311
Ensembl chrNW_004936481:21,342,786...21,371,328
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Osmr |
oncostatin M receptor |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936518:3,320,057...3,381,518
Ensembl chrNW_004936518:3,318,803...3,382,184
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G |
Oxtr |
oxytocin receptor |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17043644 |
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NCBI chrNW_004936602:4,241,743...4,259,866
Ensembl chrNW_004936602:4,241,737...4,260,549
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G |
Paox |
polyamine oxidase |
susceptibility |
ISO |
DNA:SNPs: :rs7316, rs1046175(human) |
RGD |
PMID:31016788 |
RGD:151667418 |
NCBI chrNW_004936486:19,503,631...19,511,918
Ensembl chrNW_004936486:19,503,631...19,511,920
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G |
Pbrm1 |
polybromo 1 |
disease_progression |
ISO |
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RGD |
PMID:32195359 |
RGD:150340625 |
NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052
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Pdpk1 |
3-phosphoinositide dependent protein kinase 1 |
disease_progression |
ISO |
mRNA:increased expression:blood serum |
RGD |
PMID:25064732 |
RGD:13503320 |
NCBI chrNW_004936694:1,444,819...1,487,628
Ensembl chrNW_004936694:1,444,880...1,488,265 Ensembl chrNW_004936694:1,444,880...1,488,265
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Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500
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G |
Pgam1 |
phosphoglycerate mutase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936636:2,240,452...2,248,689
Ensembl chrNW_004936636:2,236,508...2,248,768
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Phgdh |
phosphoglycerate dehydrogenase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26482881 |
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NCBI chrNW_004936627:4,414,122...4,448,347
Ensembl chrNW_004936627:4,414,122...4,448,623
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
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ISO |
ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma |
ClinVar |
PMID:15016963 PMID:15520168 PMID:15608678 PMID:15930273 PMID:17376864 PMID:17673550 PMID:20593314 PMID:21078999 PMID:22120714 PMID:22370636 PMID:22658544 PMID:22729222 PMID:22729223 PMID:22729224 PMID:23066039 PMID:23100325 PMID:23946963 PMID:24033266 PMID:24782230 PMID:25599672 PMID:25741868 PMID:25880439 PMID:26266975 PMID:26266985 PMID:26627007 PMID:26637981 PMID:26822237 PMID:26851524 PMID:27126994 PMID:27626068 PMID:27631024 PMID:28151489 PMID:28425981 PMID:28492532 PMID:29446767 PMID:29661094 PMID:29988677 PMID:30376034 PMID:30543347 PMID:31536475 PMID:31775759 PMID:33054853 PMID:34008892 PMID:34496175 PMID:35483878 PMID:37667289 PMID:37712948 More...
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NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
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Plau |
plasminogen activator, urokinase |
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ISO |
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RGD |
PMID:20937265 |
RGD:4892055 |
NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877
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Plbd1 |
phospholipase B domain containing 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936587:2,869,059...2,918,628
Ensembl chrNW_004936587:2,869,006...2,918,511
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G |
Plcg1 |
phospholipase C gamma 1 |
treatment |
ISO |
human cell line in a mouse model |
RGD |
PMID:33928024 |
RGD:151665816 |
NCBI chrNW_004936561:598,372...631,575
Ensembl chrNW_004936561:598,382...631,581
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G |
Pole |
DNA polymerase epsilon, catalytic subunit |
ameliorates |
ISO |
DNA:mutations:multiple (human) |
RGD |
PMID:32433714 |
RGD:151347639 |
NCBI chrNW_004936660:2,575,255...2,622,867
Ensembl chrNW_004936660:2,575,360...2,622,852
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G |
Ppia |
peptidylprolyl isomerase A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936478:19,669,727...19,673,355
Ensembl chrNW_004936478:19,669,506...19,673,398
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G |
Prame |
PRAME nuclear receptor transcriptional regulator |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16179254 |
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NCBI chrNW_004936619:1,748,337...1,751,748
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G |
Prdm14 |
PR/SET domain 14 |
disease_progression |
ISO |
DNA:hypermethylation |
RGD |
PMID:23690269 PMID:27777637 |
RGD:150530468 RGD:152998954 |
NCBI chrNW_004936496:14,789,443...14,820,967
Ensembl chrNW_004936496:14,806,928...14,820,967
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G |
Prdx1 |
peroxiredoxin 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
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NCBI chrNW_004936474:26,641,776...26,653,291
Ensembl chrNW_004936474:26,639,259...26,653,328
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G |
Prex2 |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 |
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ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:31711559 |
RGD:151665187 |
NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:23632475 |
RGD:150404268 |
NCBI chrNW_004936518:1,817,051...1,843,376
Ensembl chrNW_004936518:1,804,969...1,843,380
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G |
Prkcb |
protein kinase C beta |
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ISO |
DNA:hypermethylation:promoter:lung |
RGD |
PMID:28422739 |
RGD:13503321 |
NCBI chrNW_004936501:8,410,273...8,729,238
Ensembl chrNW_004936501:8,437,715...8,728,716
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G |
Prr13 |
proline rich 13 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21157449 |
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NCBI chrNW_004936512:10,717,905...10,721,348
Ensembl chrNW_004936512:10,718,654...10,720,748
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G |
Psat1 |
phosphoserine aminotransferase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26482881 |
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NCBI chrNW_004936632:4,392,165...4,422,670
Ensembl chrNW_004936632:4,391,459...4,423,264
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G |
Pten |
phosphatase and tensin homolog |
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ISO |
mRNA:decreased expression:lung (human) DNA:loss of heterozygosity:cds: (human) |
RGD |
PMID:9458098 PMID:20223231 PMID:22956424 |
RGD:12832745 RGD:152998889 RGD:152998901 |
NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
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G |
Ptges |
prostaglandin E synthase |
severity |
ISO |
protein:increased expression:lung |
RGD |
PMID:20592629 |
RGD:5135302 |
NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922
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G |
Ptgis |
prostaglandin I2 synthase |
severity |
ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:16314486 |
RGD:151347842 |
NCBI chrNW_004936514:4,775,884...4,814,574
Ensembl chrNW_004936514:4,791,031...4,812,027
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
severity |
ISO |
DNA:SNP: :929G>C(human) protein:increased expression:lung |
RGD |
PMID:20016751 PMID:20592629 |
RGD:5135302 RGD:5135471 |
NCBI chrNW_004936481:3,821,564...3,828,086
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G |
Pthlh |
parathyroid hormone like hormone |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:17676588 |
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NCBI chrNW_004936760:197,525...209,212
Ensembl chrNW_004936760:197,525...209,518
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G |
Ptprb |
protein tyrosine phosphatase receptor type B |
disease_progression |
ISO |
mRNA:decreased expression:lung (human) human cells in mouse model |
RGD |
PMID:27314562 |
RGD:151361281 |
NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715
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G |
Pxn |
paxillin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21159652 |
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NCBI chrNW_004936668:660,415...709,282
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G |
Pycard |
PYD and CARD domain containing |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16778195 |
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NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805
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G |
Rad21 |
RAD21 cohesin complex component |
susceptibility exacerbates |
ISO |
DNA:SNP:intron: (rs1374297) (human) mRNA:increased expression:lung (human) |
RGD |
PMID:28977903 PMID:32178590 |
RGD:150520031 RGD:150520036 |
NCBI chrNW_004936470:29,377,793...29,403,422
Ensembl chrNW_004936470:29,377,734...29,407,312
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Rad52 |
RAD52 homolog, DNA repair protein |
susceptibility |
ISO |
DNA:SNPs,haplotype:multiple |
RGD |
PMID:32401173 |
RGD:151660355 |
NCBI chrNW_004936606:1,070,336...1,099,684
Ensembl chrNW_004936606:1,066,905...1,099,703
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16862215 |
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NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096
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G |
Rarb |
retinoic acid receptor beta |
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ISO |
DNA:hypermethylation:lung |
RGD |
PMID:18349282 PMID:23599765 |
RGD:13503323 RGD:13503324 |
NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885
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G |
Rassf1 |
Ras association domain family member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism DNA:hypermethylation |
CTD RGD |
PMID:18337602 PMID:27777637 |
RGD:152998954 |
NCBI chrNW_004936529:1,857,177...1,866,198
Ensembl chrNW_004936529:1,857,145...1,867,260
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Rassf5 |
Ras association domain family member 5 |
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ISO |
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RGD |
PMID:20434789 |
RGD:13503325 |
NCBI chrNW_004936557:5,988,578...6,014,214
Ensembl chrNW_004936557:5,988,554...6,045,274
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Rb1 |
RB transcriptional corepressor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16862215 |
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NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846
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Rbm7 |
RNA binding motif protein 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15496427 |
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NCBI chrNW_004936612:239,618...247,277
Ensembl chrNW_004936612:240,340...247,197
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G |
Reck |
reversion inducing cysteine rich protein with kazal motifs |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17233834 |
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NCBI chrNW_004936524:4,021,666...4,099,703
Ensembl chrNW_004936524:4,021,660...4,099,705
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Rela |
RELA proto-oncogene, NF-kB subunit |
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ISO |
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RGD |
PMID:16287968 |
RGD:2298765 |
NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813
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G |
Rheb |
Ras homolog, mTORC1 binding |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20554106 |
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NCBI chrNW_004936527:6,832,286...6,877,938
Ensembl chrNW_004936527:6,832,169...6,878,164
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G |
Rnf168 |
ring finger protein 168 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34873829 |
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NCBI chrNW_004936784:1,073,236...1,094,575
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G |
Robo1 |
roundabout guidance receptor 1 |
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ISO |
mRNA:altered expression:lung |
RGD |
PMID:15264215 |
RGD:2314868 |
NCBI chrNW_004936505:4,329,428...4,711,310
Ensembl chrNW_004936505:4,330,303...4,709,655
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Ros1 |
ROS proto-oncogene 1, receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22215748 PMID:22585869 PMID:22617245 PMID:22919003 |
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NCBI chrNW_004936658:382,025...506,818
Ensembl chrNW_004936658:382,261...506,818
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G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17195088 |
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NCBI chrNW_004936475:17,173,170...17,176,446
Ensembl chrNW_004936475:17,173,165...17,176,463
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G |
Rrm1 |
ribonucleotide reductase catalytic subunit M1 |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:19002265 PMID:21496433 |
RGD:127229933 |
NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793
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G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
treatment |
ISO |
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RGD |
PMID:19002265 |
RGD:127229933 |
NCBI chrNW_004936532:6,348,041...6,390,144
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G |
Runx2 |
RUNX family transcription factor 2 |
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ISO |
human cells in mouse model |
RGD |
PMID:30780105 |
RGD:152995466 |
NCBI chrNW_004936476:14,695,965...14,818,246
Ensembl chrNW_004936476:14,695,965...14,905,157
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G |
Runx3 |
RUNX family transcription factor 3 |
|
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:18349282 |
RGD:13503324 |
NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910
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G |
Rxrg |
retinoid X receptor gamma |
|
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:20113835 |
RGD:13503326 |
NCBI chrNW_004936481:19,789,753...19,826,665
Ensembl chrNW_004936481:19,789,641...19,826,698
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Scgb3a2 |
secretoglobin family 3A member 2 |
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ISO |
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RGD |
PMID:20466451 |
RGD:5147390 |
NCBI chrNW_004936504:6,933,641...6,936,838
Ensembl chrNW_004936504:6,933,769...6,936,838
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G |
Sdc4 |
syndecan 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22919003 |
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NCBI chrNW_004936514:7,528,538...7,562,391
Ensembl chrNW_004936514:7,555,685...7,562,391
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G |
Sdha |
succinate dehydrogenase complex flavoprotein subunit A |
susceptibility |
ISO |
DNA:SNP: 3'utr (rs13173911) (human) |
RGD |
PMID:25576295 |
RGD:150340558 |
NCBI chrNW_004936815:1,148,963...1,167,585
Ensembl chrNW_004936815:1,148,963...1,167,568
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Sdhc |
succinate dehydrogenase complex subunit C |
exacerbates |
ISO |
DNA:SNP: 3'utr (rs12064957) (human) |
RGD |
PMID:25576295 |
RGD:150340558 |
NCBI chrNW_004936903:592,641...636,845
Ensembl chrNW_004936903:601,355...636,092
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Selenos |
selenoprotein S |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20471133 |
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NCBI chrNW_004936483:2,589,773...2,600,837
Ensembl chrNW_004936483:2,589,828...2,599,987
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G |
Serpinf1 |
serpin family F member 1 |
|
ISO |
protein:increased expression:serum, pleural effusion (human) |
RGD |
PMID:20230924 |
RGD:27226710 |
NCBI chrNW_004936538:7,885,816...7,898,308
Ensembl chrNW_004936538:7,885,475...7,899,113
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G |
Sftpb |
surfactant protein B |
susceptibility |
ISO |
DNA:SNPs: :rs7316, rs9752 (human) |
RGD |
PMID:31016788 |
RGD:151667418 |
NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466
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Sftpd |
surfactant protein D |
disease_progression |
ISO |
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RGD |
PMID:20401612 |
RGD:4143490 |
NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099
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G |
Shmt2 |
serine hydroxymethyltransferase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26482881 |
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NCBI chrNW_004936646:1,422,844...1,427,929
Ensembl chrNW_004936646:1,422,817...1,429,037
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G |
Slc34a2 |
solute carrier family 34 member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22617245 PMID:22919003 |
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NCBI chrNW_004936477:3,954,377...3,975,259
Ensembl chrNW_004936477:3,956,061...3,966,392
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G |
Slc3a2 |
solute carrier family 3 member 2 |
severity disease_progression sexual_dimorphism |
ISO |
DNA:SNP:5'utr: (rs105929) (human) protein:increased expression:lung (human) |
RGD |
PMID:22110199 PMID:24782339 PMID:25084765 |
RGD:151361206 RGD:152995442 RGD:152995443 |
NCBI chrNW_004936581:424,801...441,592
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Slc67a1 |
solute carrier family 67 member 1 |
disease_progression |
ISO |
protein:increased expression:lung (human) mRNA:increased expression:lung (human) |
RGD |
PMID:22237119 PMID:25498886 |
RGD:150557424 RGD:150557425 |
NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345
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G |
Slc7a5 |
solute carrier family 7 member 5 |
disease_progression treatment |
ISO |
|
RGD |
PMID:21187458 PMID:22110199 |
RGD:151361159 RGD:151361206 |
NCBI chrNW_004936641:1,513,110...1,538,955
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G |
Smad3 |
SMAD family member 3 |
|
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:25375657 |
RGD:11074609 |
NCBI chrNW_004936471:27,080,662...27,185,861
Ensembl chrNW_004936471:27,080,575...27,189,793
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Smarca4 |
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 |
|
ISO |
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RGD |
PMID:15287030 |
RGD:2302526 |
NCBI chrNW_004936659:1,152,846...1,246,718
Ensembl chrNW_004936659:1,169,792...1,249,213
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G |
Snap47 |
synaptosome associated protein 47 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34664776 |
|
NCBI chrNW_004936864:313,650...381,553
Ensembl chrNW_004936864:318,096...377,526
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G |
Socs1 |
suppressor of cytokine signaling 1 |
disease_progression |
ISO |
|
RGD |
PMID:31910343 |
RGD:150573699 |
NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165
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G |
Socs2 |
suppressor of cytokine signaling 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35305058 |
|
NCBI chrNW_004936507:10,013,982...10,015,480
Ensembl chrNW_004936507:10,012,101...10,014,456
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G |
Sod2 |
superoxide dismutase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11731445 PMID:17094902 |
|
NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
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G |
Sox30 |
SRY-box transcription factor 30 |
disease_progression |
ISO |
|
RGD |
PMID:32443323 |
RGD:151660331 |
NCBI chrNW_004936515:5,501,315...5,537,946
Ensembl chrNW_004936515:5,458,393...5,537,946
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Spop |
speckle type BTB/POZ protein |
ameliorates |
ISO |
mRNA, protein:increased expression:lung (human) |
RGD |
PMID:28927035 |
RGD:153298923 |
NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155
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G |
Spp1 |
secreted phosphoprotein 1 |
|
ISO |
|
RGD |
PMID:16533775 |
RGD:1581361 |
NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
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G |
Srsf1 |
serine and arginine rich splicing factor 1 |
severity |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:20682707 PMID:23071587 |
RGD:11038729 RGD:150429662 |
NCBI chrNW_004936490:5,055,258...5,059,118
Ensembl chrNW_004936490:5,055,253...5,059,116
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G |
Srsf2 |
serine and arginine rich splicing factor 2 |
|
ISO |
protein:increased expression:lung epithelium,nucleus |
RGD |
PMID:23071587 |
RGD:150429662 |
NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164
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G |
Stat3 |
signal transducer and activator of transcription 3 |
severity |
ISO |
CTD Direct Evidence: marker/mechanism protein:increased phosphorylation:lung (human) |
CTD RGD |
PMID:21549414 PMID:22977534 |
RGD:152023747 |
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
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G |
Stim1 |
stromal interaction molecule 1 |
|
ISO |
mRNA:increased expression:blood plasma (human) |
RGD |
PMID:32184656 |
RGD:152995359 |
NCBI chrNW_004936498:849,775...1,063,552
Ensembl chrNW_004936498:849,739...1,063,552
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G |
Syp |
synaptophysin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21595568 |
|
NCBI chrNW_004936721:1,062,206...1,075,935
Ensembl chrNW_004936721:1,062,217...1,075,988
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G |
Tab2 |
TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
|
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:34551195 |
RGD:155663369 |
NCBI chrNW_004936489:2,371,953...2,421,882
Ensembl chrNW_004936489:2,372,216...2,424,515
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G |
Tent5a |
terminal nucleotidyltransferase 5A |
susceptibility |
ISO |
DNA:repeats: : |
RGD |
PMID:25884493 |
RGD:14390136 |
NCBI chrNW_004936510:8,813,977...8,820,909
Ensembl chrNW_004936510:8,814,292...8,816,929
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G |
Tert |
telomerase reverse transcriptase |
disease_progression |
ISO |
DNA:SNP: :rs2736098(human) CTD Direct Evidence: marker/mechanism DNA:SNPs, haplotype: :rs2853669,rs2736108(human) |
RGD CTD |
PMID:21252717 PMID:24679952 PMID:27982019 |
RGD:150530632 RGD:150530644 |
NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697
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Tes |
testin LIM domain protein |
ameliorates |
ISO |
|
RGD |
PMID:28000866 |
RGD:597621667 |
NCBI chrNW_004936589:2,755,905...2,796,244
Ensembl chrNW_004936589:2,755,903...2,796,308
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G |
Tet2 |
tet methylcytosine dioxygenase 2 |
|
ISO |
DNA:mutations:multiple |
RGD |
PMID:32554069 |
RGD:150429694 |
NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615
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G |
Tgfa |
transforming growth factor alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16230376 |
|
NCBI chrNW_004936491:14,659,089...14,758,614
Ensembl chrNW_004936491:14,657,100...14,758,848
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G |
Thbd |
thrombomodulin |
disease_progression |
ISO |
|
RGD |
PMID:20607726 |
RGD:5685035 |
NCBI chrNW_004936620:2,563,900...2,568,117
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
disease_progression |
ISO |
|
RGD |
PMID:30233216 |
RGD:151708743 |
NCBI chrNW_004936492:6,996,627...7,046,137
Ensembl chrNW_004936492:6,996,613...7,046,190
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G |
Tk1 |
thymidine kinase 1 |
|
ISO |
protein:increased expression:serum (human) |
RGD |
PMID:15583816 |
RGD:2317237 |
NCBI chrNW_004936594:2,784,891...2,794,693
Ensembl chrNW_004936594:2,784,226...2,794,830
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G |
Tmem135 |
transmembrane protein 135 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chrNW_004936736:1,986,361...2,113,455
Ensembl chrNW_004936736:1,978,110...2,113,451
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G |
Tnf |
tumor necrosis factor |
|
ISO |
protein:increased expression:lung DNA:SNPs: : |
RGD |
PMID:9669810 PMID:19505916 |
RGD:4142793 RGD:4143264 |
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
disease_progression severity |
ISO |
protein:increased expression:serum (human) DNA:snp:5' utr:g.-329G>T rs4149570 (human) |
RGD |
PMID:20422457 PMID:20824709 |
RGD:5131156 RGD:5131202 |
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
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G |
Tp53 |
tumor protein p53 |
treatment |
ISO |
human cells in mouse model CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:17290066 PMID:23435014 PMID:23632475 PMID:24688052 PMID:30381462 |
RGD:150404268 |
NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
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G |
Tp53bp1 |
tumor protein p53 binding protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chrNW_004936471:6,589,395...6,668,242
Ensembl chrNW_004936471:6,589,564...6,668,305
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G |
Tp73 |
tumor protein p73 |
treatment |
ISO |
DNA:SNP:intron: (rs3765701) (human) |
RGD |
PMID:21965272 |
RGD:151347589 |
NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464
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G |
Trmt11 |
tRNA methyltransferase 11 homolog |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chrNW_004936639:3,442,026...3,494,303
Ensembl chrNW_004936639:3,440,703...3,494,362
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G |
Ttr |
transthyretin |
disease_progression |
ISO |
protein:decreased expression:blood serum (human) |
RGD |
PMID:31031974 |
RGD:151664739 |
NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566
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G |
Tymp |
thymidine phosphorylase |
|
ISO |
|
RGD |
PMID:19671868 |
RGD:2325156 |
NCBI chrNW_004936629:315,609...320,356
Ensembl chrNW_004936629:315,610...319,076
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G |
Ubr5 |
ubiquitin protein ligase E3 component n-recognin 5 |
exacerbates |
ISO |
circRNA:decreased expression:lung (human) |
RGD |
PMID:29944885 |
RGD:151665198 |
NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17094902 |
|
NCBI chrNW_004936482:8,551,749...8,563,586
Ensembl chrNW_004936482:8,551,603...8,563,651
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G |
Vegfa |
vascular endothelial growth factor A |
disease_progression |
ISO |
protein:increased expression:plasma CTD Direct Evidence: marker/mechanism protein:inctreased expression:lung (human) |
RGD CTD |
PMID:15956251 PMID:21481963 PMID:22977534 |
RGD:126925199 RGD:152023747 |
NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
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G |
Wee1 |
WEE1 G2 checkpoint kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34664776 |
|
NCBI chrNW_004936528:8,573,837...8,588,988
Ensembl chrNW_004936528:8,573,497...8,588,576
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G |
Wrap53 |
WD repeat containing antisense to TP53 |
disease_progression |
ISO |
RNA:increased expression:lung DNA:hypermethylation:promoter |
RGD |
PMID:30344734 PMID:31281482 |
RGD:21081513 RGD:21081519 |
NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791
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G |
Xpc |
XPC complex subunit, DNA damage recognition and repair factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27777383 |
|
NCBI chrNW_004936602:118,173...139,884
Ensembl chrNW_004936602:118,188...139,675
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G |
Xpo1 |
exportin 1 |
treatment ameliorates |
ISO |
human cell line in a mouse model |
RGD |
PMID:24946002 PMID:31113936 |
RGD:151665798 RGD:151667438 |
NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343
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G |
Xpo5 |
exportin 5 |
severity |
ISO |
DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) |
RGD |
PMID:21799879 |
RGD:11041736 |
NCBI chrNW_004936476:16,434,629...16,481,044
Ensembl chrNW_004936476:16,434,638...16,481,044
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G |
Xrcc1 |
X-ray repair cross complementing 1 |
treatment susceptibility severity |
ISO |
DNA:missense mutation:p.R399Q (human) DNA:missense mutation:cds: p.R194W (human) DNA:SNP:3'utr: (rs25487) (human) DNA:missense mutations:cds:p.R194W, p.R399Q (human) |
RGD |
PMID:15301704 PMID:19157633 PMID:19958624 PMID:22152690 PMID:23549037 PMID:24446315 PMID:24782167 PMID:25308691 PMID:26097609 PMID:26345972 More...
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RGD:11097268 RGD:11251107 RGD:11538163 RGD:127229950 RGD:151232295 RGD:151232297 RGD:151347175 RGD:151347402 RGD:151347410 RGD:151347427 |
NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777
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G |
Zfhx3 |
zinc finger homeobox 3 |
ameliorates exacerbates |
ISO |
DNA:mutations:multiple (human) mRNA:decreased expression:lung (human) |
RGD |
PMID:23144151 PMID:32653938 |
RGD:151361163 RGD:151361164 |
NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544
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G |
Znf462 |
zinc finger protein 462 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29059373 |
|
NCBI chrNW_004936559:5,510,933...5,644,727
Ensembl chrNW_004936559:5,510,892...5,596,528
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G |
Alx4 |
ALX homeobox 4 |
ameliorates |
ISO |
|
RGD |
PMID:24037716 |
RGD:153344522 |
NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000
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G |
Ccnd1 |
cyclin D1 |
|
ISO |
protein:increased expression:lung |
RGD |
PMID:14674039 |
RGD:13434930 |
Ensembl chrNW_004936599:973,838...983,316
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G |
Dnmt1 |
DNA methyltransferase 1 |
disease_progression |
ISO |
|
RGD |
PMID:19484794 |
RGD:4140940 |
NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416
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G |
Egfr |
epidermal growth factor receptor |
|
ISO |
DNA:mutations:exons: protein:increased expression:tumor (human) DNA:snp:cds:p.T790M (human) |
RGD |
PMID:15737014 PMID:21419590 PMID:26059825 |
RGD:11075076 RGD:5131465 RGD:5131630 |
NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
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G |
Egr1 |
early growth response 1 |
|
ISO |
mRNA:decreased expression:tumor (human) |
RGD |
PMID:11948124 |
RGD:5131942 |
NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749
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G |
Gstp1 |
glutathione S-transferase pi 1 |
|
ISO |
DNA:hypermethylation:promoter (human) |
RGD |
PMID:19484794 |
RGD:4140940 |
NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050
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G |
Kras |
KRAS proto-oncogene, GTPase |
|
ISO |
DNA:mutations:cds: |
RGD |
PMID:26059825 |
RGD:11075076 |
NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
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G |
Tp53 |
tumor protein p53 |
|
ISO |
DNA:mutations:exons: |
RGD |
PMID:26059825 |
RGD:11075076 |
NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
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G |
Slc7a5 |
solute carrier family 7 member 5 |
disease_progression |
ISO |
|
RGD |
PMID:18440724 |
RGD:151361285 |
NCBI chrNW_004936641:1,513,110...1,538,955
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G |
Abce1 |
ATP binding cassette subfamily E member 1 |
severity |
ISO |
mRNA, protein:increased expression:lung (human) |
RGD |
PMID:18788636 |
RGD:11046260 |
NCBI chrNW_004936535:3,956,490...3,985,002
Ensembl chrNW_004936535:3,955,682...3,985,223
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G |
Acsl4 |
acyl-CoA synthetase long chain family member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144
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G |
Adam19 |
ADAM metallopeptidase domain 19 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936515:5,603,095...5,683,347
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G |
Adam28 |
ADAM metallopeptidase domain 28 |
exacerbates treatment disease_progression |
ISO |
protein:increased expression:lung |
RGD |
PMID:20112342 PMID:26800504 PMID:29882245 PMID:30190423 |
RGD:11531771 RGD:153297792 RGD:153297794 RGD:153297795 |
NCBI chrNW_004936555:7,615,639...7,660,776
Ensembl chrNW_004936555:7,617,822...7,664,215
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G |
Adamtsl3 |
ADAMTS like 3 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936483:18,191,568...18,523,988
Ensembl chrNW_004936483:18,193,198...18,522,028
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G |
Adgrg6 |
adhesion G protein-coupled receptor G6 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936625:3,552,611...3,688,281
Ensembl chrNW_004936625:3,552,602...3,688,287
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G |
Ahcy |
adenosylhomocysteinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936561:6,314,797...6,333,961
Ensembl chrNW_004936561:6,314,705...6,334,439
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G |
Ahr |
aryl hydrocarbon receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12597446 |
|
NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
disease_progression |
ISO |
|
RGD |
PMID:30727821 |
RGD:27226687 |
NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214
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G |
Alk |
ALK receptor tyrosine kinase |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874
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G |
Alox12b |
arachidonate 12-lipoxygenase, 12R type |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30258081 |
|
NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985
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G |
Alox5 |
arachidonate 5-lipoxygenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30258081 |
|
NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931
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G |
Alx1 |
ALX homeobox 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
|
NCBI chrNW_004936507:2,775,752...2,797,065
Ensembl chrNW_004936507:2,775,752...2,797,062
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G |
Alx4 |
ALX homeobox 4 |
disease_progression |
ISO |
|
RGD |
PMID:18978557 |
RGD:153350135 |
NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000
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G |
Anapc2 |
anaphase promoting complex subunit 2 |
severity |
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:12036940 |
RGD:14696682 |
NCBI chrNW_004936669:797,475...808,952
Ensembl chrNW_004936669:797,318...811,721
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G |
Anp32a |
acidic nuclear phosphoprotein 32 family member A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936471:28,601,816...28,635,002
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G |
Anxa1 |
annexin A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
|
NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413
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G |
Anxa5 |
annexin A5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
|
NCBI chrNW_004936662:926,302...959,964
Ensembl chrNW_004936662:925,940...939,451
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G |
Apc |
APC regulator of WNT signaling pathway |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936877:666,545...669,351
Ensembl chrNW_004936877:666,523...669,338
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G |
Apoa1 |
apolipoprotein A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854
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G |
Apoc3 |
apolipoprotein C3 |
|
ISO |
protein:altered glycosylation:: |
RGD |
PMID:19322776 |
RGD:153344619 |
NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603
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Aqp4 |
aquaporin 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354
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G |
Arhgap35 |
Rho GTPase activating protein 35 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
|
NCBI chrNW_004936664:714,036...788,584
Ensembl chrNW_004936664:713,984...789,344
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G |
Arhgap44 |
Rho GTPase activating protein 44 |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:28527113 |
RGD:401901290 |
NCBI chrNW_004936595:5,373,645...5,542,915
Ensembl chrNW_004936595:5,373,476...5,543,073
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936594:354,416...359,415
Ensembl chrNW_004936594:353,980...359,414
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G |
Atrx |
ATRX chromatin remodeler |
disease_progression |
ISO |
|
RGD |
PMID:31374064 |
RGD:127285382 |
NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620
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G |
Axin2 |
axin 2 |
disease_progression susceptibility |
ISO |
DNA:SNPs::1712 +19 G>A,148 C>T(human) DNA:SNP:cds:p.P50S(human) |
RGD |
PMID:16820935 PMID:30346805 |
RGD:151356655 RGD:151356657 |
NCBI chrNW_004936541:7,155,963...7,242,466
Ensembl chrNW_004936541:7,211,985...7,242,470
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G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
|
ISO |
mRNA,protein:increased expression:lung |
RGD |
PMID:17724461 |
RGD:153350134 |
NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190
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G |
Bap1 |
BRCA1 associated deubiquitinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25231345 |
|
NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806
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G |
Bhlhe41 |
basic helix-loop-helix family member e41 |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:18223678 |
RGD:151665316 |
NCBI chrNW_004936548:1,306,939...1,314,678
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G |
Birc3 |
baculoviral IAP repeat containing 3 |
exacerbates |
ISO |
mRNA:increased expression:B cell (human) |
RGD |
PMID:33098370 |
RGD:153323293 |
NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555
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G |
Birc5 |
baculoviral IAP repeat containing 5 |
ameliorates disease_progression |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:31964418 |
RGD:153344516 |
NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 PMID:12619120 PMID:12644542 PMID:12670889 PMID:12794760 PMID:12960123 PMID:14513361 PMID:14602780 PMID:14612909 PMID:14679157 PMID:14688025 PMID:15001635 PMID:15035987 PMID:15126572 PMID:15181070 PMID:15342696 PMID:15356022 PMID:15386408 PMID:15687339 PMID:15998781 PMID:16015629 PMID:16174717 PMID:16187918 PMID:16439621 PMID:16474404 PMID:16772349 PMID:16825433 PMID:17096326 PMID:17119447 PMID:17311103 PMID:17374713 PMID:17488796 PMID:17603483 PMID:17785355 PMID:18039235 PMID:18042262 PMID:18186519 PMID:18368129 PMID:18398503 PMID:18413255 PMID:18794803 PMID:19001320 PMID:19010912 PMID:19018267 PMID:19206169 PMID:19238210 PMID:19376813 PMID:19383316 PMID:19404918 PMID:19537845 PMID:19561230 PMID:19571295 PMID:19913317 PMID:20008640 PMID:20350999 PMID:20413299 PMID:20619739 PMID:20630094 PMID:20818844 PMID:20823850 PMID:20857202 PMID:21062266 PMID:21107320 PMID:21107323 PMID:21129611 PMID:21156289 PMID:21163703 PMID:21426297 PMID:21483012 PMID:21502544 PMID:21639808 PMID:21641636 PMID:21683865 PMID:21784453 PMID:21975775 PMID:22038996 PMID:22039425 PMID:22048237 PMID:22113612 PMID:22180495 PMID:22281684 PMID:22310681 PMID:22351686 PMID:22356324 PMID:22389471 PMID:22448344 PMID:22495831 PMID:22536370 PMID:22586120 PMID:22608338 PMID:22649091 PMID:22663011 PMID:22735384 PMID:22743296 PMID:22773810 PMID:22798288 PMID:22805292 PMID:22876591 PMID:22972589 PMID:22997239 PMID:23020132 PMID:23031422 PMID:23251002 PMID:23273605 PMID:23302800 PMID:23325582 PMID:23352452 PMID:23470635 PMID:23524406 PMID:23549875 PMID:23614898 PMID:23685455 PMID:23715574 PMID:23812671 PMID:23833300 PMID:23845441 PMID:23918947 PMID:24033266 PMID:24107445 PMID:24112392 PMID:24163374 PMID:24303953 PMID:24388723 PMID:24446311 PMID:24451042 PMID:24508103 PMID:24512911 PMID:24576830 PMID:24583796 PMID:24586605 PMID:24594804 PMID:24670642 PMID:24717435 PMID:24920063 PMID:25024077 PMID:25037139 PMID:25079330 PMID:25157968 PMID:25265492 PMID:25265494 PMID:25370471 PMID:25399551 PMID:25463315 PMID:25741868 PMID:25950823 PMID:25989278 PMID:26619011 PMID:26678033 PMID:27236105 PMID:27276561 PMID:27404270 PMID:27480103 PMID:28492532 PMID:28832562 PMID:28854169 PMID:28891408 PMID:29453417 PMID:29595366 PMID:29907801 PMID:29925953 PMID:31277584 PMID:31336229 PMID:31779674 PMID:31891627 PMID:34476331 More...
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NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
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G |
Btk |
Bruton tyrosine kinase |
susceptibility exacerbates |
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:31803536 PMID:32351880 |
RGD:151347848 RGD:151347849 |
NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441
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G |
Bzw2 |
basic leucine zipper and W2 domains 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936546:3,160,047...3,215,591
Ensembl chrNW_004936546:3,160,004...3,216,331
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G |
Cadm1 |
cell adhesion molecule 1 |
|
ISO |
DNA, mRNA:hypermethylation, decreased expression:promoter:liver |
RGD |
PMID:16814249 |
RGD:2289096 |
NCBI chrNW_004936542:569,739...883,738
Ensembl chrNW_004936542:565,843...883,609
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G |
Calr |
calreticulin |
treatment |
ISO |
human cells and recombinant gene in a mouse model |
RGD |
PMID:18245558 |
RGD:150521698 |
NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430
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G |
Capg |
capping actin protein, gelsolin like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936712:1,793,666...1,803,621
Ensembl chrNW_004936712:1,793,480...1,806,602
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G |
Cbx5 |
chromobox 5 |
disease_progression |
ISO |
mRNA,protein:increased expression:lung: |
RGD |
PMID:22900142 |
RGD:9586743 |
NCBI chrNW_004936512:11,441,770...11,480,924
Ensembl chrNW_004936512:11,450,060...11,480,727
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G |
Cbx7 |
chromobox 7 |
|
ISO |
mRNA,DNA:decreased expression, loss of heterozygosity:lung: |
RGD |
PMID:22214847 |
RGD:9587356 |
NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682
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G |
Ccnd1 |
cyclin D1 |
disease_progression treatment |
ISO |
|
RGD |
PMID:19355812 PMID:26681199 |
RGD:11536846 RGD:13434927 |
Ensembl chrNW_004936599:973,838...983,316
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G |
Ccnd2 |
cyclin D2 |
disease_progression |
ISO |
|
RGD |
PMID:30308939 |
RGD:151665105 |
NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936643:2,354,799...2,368,048
Ensembl chrNW_004936643:2,354,799...2,368,048
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G |
Cd44 |
CD44 molecule (IN blood group) |
disease_progression |
ISO |
mRNA:increased expression:lung (human) mRNA:splice variants:lung |
RGD |
PMID:18091389 PMID:29537891 |
RGD:149735539 RGD:2289345 |
NCBI chrNW_004936533:2,949,026...3,033,166
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G |
Cdc73 |
cell division cycle 73 |
exacerbates |
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:21692036 |
RGD:150537041 |
NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277
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G |
Cdh1 |
cadherin 1 |
|
ISO |
DNA:increased methylation |
RGD |
PMID:16329148 |
RGD:1599556 |
NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203
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G |
Cdk12 |
cyclin dependent kinase 12 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
|
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NCBI chrNW_004936490:14,674,783...14,759,433
Ensembl chrNW_004936490:14,674,800...14,738,818
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G |
Cdk4 |
cyclin dependent kinase 4 |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 PMID:9425228 PMID:11756559 PMID:15880589 PMID:21801156 PMID:22804906 PMID:23384855 PMID:23546221 PMID:24256466 PMID:25157968 PMID:25741868 PMID:26619011 PMID:28492532 PMID:29774366 More...
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NCBI chrNW_004936646:1,886,262...1,889,260
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G |
Cdk6 |
cyclin dependent kinase 6 |
|
ISO |
protein:increased expression:lung |
RGD |
PMID:10574260 |
RGD:13464325 |
NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516
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G |
Chd4 |
chromodomain helicase DNA binding protein 4 |
susceptibility ameliorates |
ISO |
DNA:missense mutation:CDS:p.D140E (rs7479004) (human) mRNA:increased expression:lung (human) human cells in a mouse model |
RGD |
PMID:28486105 PMID:29667179 PMID:32228507 |
RGD:151660359 RGD:153323299 RGD:153323307 |
NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149
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G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
susceptibility |
ISO |
DNA:SNP: :rs8042374(human) associated with smoking; DNA:SNP: :rs1051730(human) ClinVar Annotator: match by term: Lung adenocarcinoma |
RGD ClinVar |
PMID:20554942 PMID:24686516 PMID:27993330 |
RGD:150527848 RGD:151347530 |
NCBI chrNW_004936471:36,427,598...36,447,903
Ensembl chrNW_004936471:36,427,495...36,457,758
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G |
Chrna5 |
cholinergic receptor nicotinic alpha 5 subunit |
susceptibility disease_progression |
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma DNA:SNP: :rs503464(human) associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human) DNA:SNP:cds: p.D398N(human) |
ClinVar RGD |
PMID:19577767 PMID:20554942 PMID:23314339 PMID:27993330 |
RGD:150524359 RGD:150527848 RGD:150527849 |
NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618
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G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
|
ISO |
DNA:hypomethylation:promoter: mRNA:increased expression:lung |
RGD |
PMID:20124469 PMID:22945651 |
RGD:150527851 RGD:151361154 |
NCBI chrNW_004936471:36,408,471...36,425,571
Ensembl chrNW_004936471:36,408,447...36,426,021
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G |
Clptm1l |
CLPTM1 like |
susceptibility no_association ameliorates |
ISO |
DNA:SNP:: rs4975616(human) CTD Direct Evidence: marker/mechanism DNA:SNP: :rs401681(human) DNA:SNP::rs77518573(human) DNA:SNP:: rs31490(human) DNA:SNP::rs401681(human) mRNA:increased expression:lung |
RGD CTD |
PMID:19955392 PMID:22675468 PMID:23738012 PMID:23908149 PMID:24366883 PMID:24386361 PMID:24861918 PMID:31935503 More...
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RGD:150530483 RGD:150530485 RGD:150530498 RGD:150530499 RGD:150530502 RGD:150530635 RGD:150537098 |
NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750
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G |
Cmtr2 |
cap methyltransferase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936475:22,434,009...22,441,350
Ensembl chrNW_004936475:22,434,180...22,440,846
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G |
Col10a1 |
collagen type X alpha 1 chain |
disease_progression |
ISO |
mRNA:increased expression:lung |
RGD |
PMID:33324550 |
RGD:150429752 |
NCBI chrNW_004936824:734,499...741,674
Ensembl chrNW_004936824:734,488...769,010
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G |
Crebbp |
CREB binding protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617
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G |
Csf1r |
colony stimulating factor 1 receptor |
|
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:23702648 |
RGD:150524280 |
NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
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G |
Csrp3 |
cysteine and glycine rich protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936654:271,067...313,251
Ensembl chrNW_004936654:271,067...289,823
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G |
Ctnnb1 |
catenin beta 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar Annotator: match by term: Adenocarcinoma of lung |
ClinVar |
PMID:10192393 PMID:25741868 PMID:26619011 |
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NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
exacerbates |
ISO |
protein:increased expression:lung (human) mRNA:increased expression:lung (human) |
RGD |
PMID:19716197 PMID:30103827 |
RGD:152023735 RGD:152177480 |
NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459
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G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139
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G |
Dll4 |
delta like canonical Notch ligand 4 |
treatment |
ISO |
|
RGD |
PMID:33628824 |
RGD:155663482 |
NCBI chrNW_004936471:4,320,235...4,330,251
Ensembl chrNW_004936471:4,320,933...4,330,253
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G |
Dnmt3a |
DNA methyltransferase 3 alpha |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 PMID:22898539 PMID:22898541 PMID:24606448 PMID:24622842 PMID:24656771 PMID:25741868 PMID:26619011 PMID:26822784 PMID:26876596 PMID:27317772 PMID:27991732 PMID:28166811 PMID:28252636 PMID:28432085 PMID:28492532 PMID:28941052 PMID:29900417 PMID:30185810 PMID:30478443 PMID:31582562 PMID:31620784 PMID:31640986 PMID:31961069 PMID:32123902 PMID:32385248 PMID:34788385 More...
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NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
susceptibility |
ISO |
DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) |
RGD |
PMID:15528220 |
RGD:9589086 |
NCBI chrNW_004936485:19,547,836...19,570,716
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G |
Dok1 |
docking protein 1 |
disease_progression |
ISO |
|
RGD |
PMID:20139980 |
RGD:152177521 |
NCBI chrNW_004936556:766,522...769,557
Ensembl chrNW_004936556:766,613...771,316
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G |
Dok2 |
docking protein 2 |
exacerbates disease_progression |
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:20139980 PMID:24255704 PMID:30475228 |
RGD:152177492 RGD:152177493 RGD:152177521 |
NCBI chrNW_004936555:5,749,787...5,754,149
Ensembl chrNW_004936555:5,750,270...5,753,964
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G |
Dok3 |
docking protein 3 |
disease_progression |
ISO |
|
RGD |
PMID:20139980 |
RGD:152177521 |
NCBI chrNW_004936597:1,781,129...1,785,998
Ensembl chrNW_004936597:1,781,306...1,785,959
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G |
Dot1l |
DOT1 like histone lysine methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936588:1,288,447...1,332,489
Ensembl chrNW_004936588:1,288,392...1,330,297
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G |
E2f1 |
E2F transcription factor 1 |
|
ISO |
mRNA:increased expression:lung |
RGD |
PMID:26695082 |
RGD:13464334 |
NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026
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G |
E2f3 |
E2F transcription factor 3 |
|
ISO |
|
RGD |
PMID:16938365 |
RGD:13464341 |
NCBI chrNW_004936552:5,712,247...5,783,643
Ensembl chrNW_004936552:5,711,923...5,783,694
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
exacerbates |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:21554491 |
RGD:153298904 |
NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609
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G |
Eef2k |
eukaryotic elongation factor 2 kinase |
ameliorates |
ISO |
Human cells in mouse model |
RGD |
PMID:30522114 |
RGD:153298964 |
NCBI chrNW_004936501:7,160,134...7,205,231
Ensembl chrNW_004936501:7,160,134...7,207,377
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G |
Egf |
epidermal growth factor |
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ISO |
DNA:polymorphism: :p.A61G (human) |
RGD |
PMID:26625757 |
RGD:11538684 |
NCBI chrNW_004936563:1,058,803...1,181,393
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G |
Egfr |
epidermal growth factor receptor |
disease_progression |
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma |
RGD ClinVar |
PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 PMID:15604253 PMID:15623594 PMID:15625347 PMID:15625379 PMID:15728811 PMID:15737014 PMID:15741570 PMID:15788655 PMID:15897572 PMID:15901872 PMID:15998907 PMID:16105816 PMID:16115929 PMID:16187797 PMID:16199108 PMID:16203769 PMID:16204011 PMID:16258541 PMID:16467085 PMID:16533793 PMID:16863509 PMID:16865253 PMID:16912157 PMID:16956694 PMID:17020982 PMID:17047654 PMID:17085664 PMID:17106442 PMID:17177598 PMID:17192902 PMID:17236554 PMID:17285735 PMID:17317677 PMID:17387341 PMID:17429313 PMID:17473653 PMID:17473659 PMID:17510392 PMID:17726540 PMID:17904685 PMID:17941001 PMID:18093943 PMID:18176089 PMID:18227510 PMID:18261621 PMID:18325048 PMID:18334834 PMID:18596266 PMID:18948947 PMID:18981003 PMID:18992959 PMID:19096301 PMID:19096324 PMID:19147750 PMID:19381876 PMID:19536777 PMID:19589612 PMID:19692680 PMID:20022809 PMID:20033049 PMID:20038723 PMID:20068085 PMID:20129249 PMID:20479403 PMID:20559149 PMID:20573926 PMID:20808254 PMID:20942962 PMID:21057810 PMID:21233402 PMID:21248300 PMID:21252721 PMID:21317742 PMID:21430269 PMID:21527506 PMID:21592614 PMID:21841502 PMID:21899495 PMID:21900837 PMID:21921847 PMID:22019513 PMID:22215752 PMID:22370314 PMID:22483783 PMID:22588155 PMID:22760226 PMID:22809298 PMID:22992668 PMID:23371856 PMID:23468066 PMID:23540867 PMID:24033266 PMID:24039832 PMID:24202392 PMID:24212795 PMID:24453288 PMID:24478319 PMID:24736066 PMID:24736080 PMID:25061320 PMID:25382819 PMID:25741868 PMID:26066407 PMID:26490356 PMID:26700910 PMID:26824984 PMID:27294619 PMID:27993330 PMID:28492532 PMID:28947568 PMID:29100434 PMID:29228562 PMID:30098700 PMID:30610926 PMID:31721094 PMID:32171629 PMID:32978515 PMID:32978518 PMID:33858029 PMID:1111234672 More...
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RGD:126790475 |
NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
disease_progression |
ISO |
|
RGD |
PMID:20940408 |
RGD:9589170 |
NCBI chrNW_004936727:1,648,451...1,663,294
Ensembl chrNW_004936727:1,648,448...1,663,455
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G |
Eif2b1 |
eukaryotic translation initiation factor 2B subunit alpha |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936558:1,196,111...1,205,321
Ensembl chrNW_004936558:1,196,068...1,205,867
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G |
Eif2b4 |
eukaryotic translation initiation factor 2B subunit delta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24366584 |
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NCBI chrNW_004936493:5,213,036...5,217,670
Ensembl chrNW_004936493:5,213,055...5,217,664
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G |
Eif2b5 |
eukaryotic translation initiation factor 2B subunit epsilon |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24366584 |
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NCBI chrNW_004936578:5,716,333...5,724,869
Ensembl chrNW_004936578:5,715,512...5,725,096
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G |
Eif3e |
eukaryotic translation initiation factor 3 subunit E |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936470:36,556,666...36,599,075
Ensembl chrNW_004936470:36,556,599...36,599,264
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G |
Eml4 |
EMAP like 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22980554 PMID:22999080 |
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NCBI chrNW_004936508:9,303,639...9,447,478
Ensembl chrNW_004936508:9,303,639...9,447,548
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G |
Emx2 |
empty spiracles homeobox 2 |
exacerbates |
ISO |
mRNA,protein:decreased expression:lung (human) |
RGD |
PMID:21726823 |
RGD:153323303 |
NCBI chrNW_004936486:7,313,689...7,319,971
Ensembl chrNW_004936486:7,313,190...7,319,995
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G |
Eno1 |
enolase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 PMID:27602772 |
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NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183
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G |
Ep300 |
E1A binding protein p300 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
disease_progression |
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
RGD ClinVar |
PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 PMID:22761469 PMID:24033266 PMID:26824984 More...
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RGD:126790475 |
NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
disease_progression |
ISO |
|
RGD |
PMID:26824984 |
RGD:126790475 |
NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
disease_progression |
ISO |
|
RGD |
PMID:26824984 |
RGD:126790475 |
NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21327329 |
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NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
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G |
Ercc6 |
ERCC excision repair 6, chromatin remodeling factor |
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ISO |
mRNA, protein:increased expression:lung (human) |
RGD |
PMID:31615563 |
RGD:155260344 |
NCBI chrNW_004936728:706,499...843,447
Ensembl chrNW_004936728:761,804...844,690
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G |
Ercc6l |
ERCC excision repair 6 like, spindle assembly checkpoint helicase |
exacerbates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:35150321 |
RGD:155260359 |
NCBI chrNW_004936959:25,084...30,143
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G |
Ergic3 |
ERGIC and golgi 3 |
disease_progression ameliorates |
ISO |
mRNA,protein:increased expression:lung (human) |
RGD |
PMID:23374247 PMID:27588471 |
RGD:151708716 RGD:153323314 |
NCBI chrNW_004936561:5,256,450...5,270,073
Ensembl chrNW_004936561:5,256,417...5,270,344
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G |
Erp29 |
endoplasmic reticulum protein 29 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936558:4,531,397...4,538,943
Ensembl chrNW_004936558:4,531,471...4,538,943
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G |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
ameliorates |
ISO |
|
RGD |
PMID:33573689 |
RGD:155791670 |
NCBI chrNW_004936675:670,915...697,696
Ensembl chrNW_004936675:670,915...697,668
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
disease_progression |
ISO |
|
RGD |
PMID:24097870 |
RGD:126781716 |
NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939
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G |
Fas |
Fas cell surface death receptor |
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ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:29254206 |
RGD:151665107 |
NCBI chrNW_004936735:209,369...234,582
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G |
Fasn |
fatty acid synthase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936594:5,591,785...5,609,886
Ensembl chrNW_004936594:5,592,609...5,608,972
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G |
Fbl |
fibrillarin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936661:2,444,985...2,455,423
Ensembl chrNW_004936661:2,444,866...2,455,528
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G |
Fes |
FES proto-oncogene, tyrosine kinase |
treatment |
ISO |
human cells in a mouse model |
RGD |
PMID:31573955 |
RGD:153323295 |
NCBI chrNW_004936483:16,123,938...16,135,044
Ensembl chrNW_004936483:16,123,779...16,135,044
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G |
Fgf10 |
fibroblast growth factor 10 |
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ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898
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G |
Fgf18 |
fibroblast growth factor 18 |
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ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:19296538 |
RGD:150429981 |
NCBI chrNW_004936609:3,677,661...3,706,511
Ensembl chrNW_004936609:3,677,237...3,706,517
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G |
Fgf9 |
fibroblast growth factor 9 |
disease_progression |
ISO |
mRNA:decreased expression:lung (human) protein:increased expression:lung (human) |
RGD |
PMID:19296538 PMID:19358281 PMID:20464547 |
RGD:150429981 RGD:152177688 RGD:152975620 |
NCBI chrNW_004936720:282,291...316,629
Ensembl chrNW_004936720:279,521...316,674
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G |
Fgfr4 |
fibroblast growth factor receptor 4 |
disease_progression exacerbates |
ISO |
DNA:SNP:exon 9: p.G388R (human) human cells in mouse model DNA:SNP:exon 9: p.G388R (rs351855)(human) |
RGD |
PMID:16061909 PMID:19296538 PMID:29402970 |
RGD:150429976 RGD:150429981 RGD:150429984 |
NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
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G |
Fkbp11 |
FKBP prolyl isomerase 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936512:6,731,942...6,736,677
Ensembl chrNW_004936512:6,731,942...6,735,456
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G |
Flt1 |
fms related receptor tyrosine kinase 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041
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G |
Foxa1 |
forkhead box A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung |
CTD RGD |
PMID:12234996 PMID:29072684 PMID:34254728 |
RGD:151665758 RGD:151665822 |
NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
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G |
Foxo3 |
forkhead box O3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19380174 |
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NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837
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G |
Foxp1 |
forkhead box P1 |
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ISO |
mRNA:decreased expression:lung (rat) |
RGD |
PMID:16023287 |
RGD:11561933 |
NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
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G |
Foxp2 |
forkhead box P2 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936589:4,120,162...4,661,258
Ensembl chrNW_004936589:4,123,182...4,382,005
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G |
Foxp4 |
forkhead box P4 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
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G |
Frzb |
frizzled related protein |
severity |
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:27623992 |
RGD:32716395 |
NCBI chrNW_004936509:11,440,414...11,471,042
Ensembl chrNW_004936509:11,440,148...11,470,967
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G |
Fubp1 |
far upstream element binding protein 1 |
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ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:32481602 |
RGD:151361197 |
NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936709:1,243,149...1,247,782
Ensembl chrNW_004936709:1,243,147...1,247,903
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G |
Gar1 |
GAR1 ribonucleoprotein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936563:1,006,475...1,014,808
Ensembl chrNW_004936563:1,006,517...1,014,808
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G |
Gart |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936500:8,750,928...8,782,303
Ensembl chrNW_004936500:8,753,463...8,786,236
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G |
Gjb2 |
gap junction protein beta 2 |
|
ISO |
DNA, mRNA:hypermethylation, decreased expression:lung |
RGD |
PMID:16637067 |
RGD:11568669 |
NCBI chrNW_004936720:1,528,205...1,530,296
Ensembl chrNW_004936720:1,528,249...1,528,929
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G |
Gng11 |
G protein subunit gamma 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24366584 |
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NCBI chrNW_004936803:57,659...62,005
Ensembl chrNW_004936803:57,151...62,047
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G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936697:2,079,396...2,087,602
Ensembl chrNW_004936697:2,079,470...2,086,877
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G |
Golm1 |
golgi membrane protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936680:1,463,991...1,528,322
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G |
Gpi |
glucose-6-phosphate isomerase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936570:1,582,120...1,608,537
Ensembl chrNW_004936570:1,579,372...1,608,788
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G |
Gpx3 |
glutathione peroxidase 3 |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:23374247 |
RGD:151708716 |
NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
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G |
Grwd1 |
glutamate rich WD repeat containing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936664:2,548,178...2,555,234
Ensembl chrNW_004936664:2,547,789...2,555,887
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G |
Hells |
helicase, lymphoid specific |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936601:626,354...662,477
Ensembl chrNW_004936601:626,823...662,465
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G |
Hk1 |
hexokinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936521:9,067,062...9,139,112
Ensembl chrNW_004936521:9,066,999...9,159,793
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G |
Hk2 |
hexokinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936556:1,054,143...1,113,425
Ensembl chrNW_004936556:1,054,021...1,113,450
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G |
Hmgb2 |
high mobility group box 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24366584 PMID:27602772 |
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NCBI chrNW_004936516:4,536,664...4,539,331
Ensembl chrNW_004936516:4,534,306...4,539,387
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936512:11,481,017...11,487,737
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G |
Hoxb7 |
homeobox B7 |
severity |
ISO |
protein:increased expression:lung epithelium (human) |
RGD |
PMID:22911672 |
RGD:10402176 |
NCBI chrNW_004936490:12,777,005...12,780,515
Ensembl chrNW_004936490:12,777,020...12,780,522
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G |
Hras |
HRas proto-oncogene, GTPase |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17601930 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20301680 PMID:20660566 PMID:20859122 PMID:20937837 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22420426 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25695684 PMID:25741868 PMID:25815234 PMID:25914166 PMID:26467025 PMID:26619011 PMID:26778095 PMID:27195699 PMID:27283355 PMID:27444071 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28328122 PMID:28492532 PMID:29493581 PMID:30055033 PMID:30138938 PMID:30191474 PMID:31222966 PMID:31394527 PMID:31560489 PMID:31564432 PMID:31775759 PMID:32165824 PMID:32371413 PMID:32732226 PMID:33027564 PMID:33372952 PMID:34008892 PMID:34958143 PMID:168335863 More...
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NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
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G |
Hsd17b10 |
hydroxysteroid 17-beta dehydrogenase 10 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936751:399,743...402,200
Ensembl chrNW_004936751:399,701...402,344
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
|
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:23374247 |
RGD:151708716 |
NCBI chrNW_004936492:10,513,908...10,528,281
Ensembl chrNW_004936492:10,513,908...10,528,285
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186
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Htr4 |
5-hydroxytryptamine receptor 4 |
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ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936504:6,146,974...6,306,000
Ensembl chrNW_004936504:6,146,974...6,265,631
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Htra1 |
HtrA serine peptidase 1 |
disease_progression |
ISO |
human cells in mouse model |
RGD |
PMID:24356998 |
RGD:152975621 |
NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739
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Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
disease_progression |
ISO |
mRNA:increased expression:lung (human) ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma protein:increased expression:blood plasma (human) |
RGD ClinVar |
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 PMID:21352804 PMID:21446021 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22898539 PMID:23558169 PMID:24046070 PMID:24606448 PMID:25043048 PMID:25157968 PMID:25741868 PMID:26619011 PMID:27993330 PMID:29537891 PMID:30231226 PMID:36201590 More...
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RGD:149735539 RGD:149735540 |
NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363
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Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
severity |
ISO |
protein:increased expression:blood serum (human) protein:increased expression:lung (human) |
RGD |
PMID:29465809 PMID:30128035 |
RGD:149735564 RGD:149735567 |
NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
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Igf2r |
insulin like growth factor 2 receptor |
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ISO |
mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) |
RGD |
PMID:12503077 |
RGD:1298968 |
NCBI chrNW_004936489:11,447,043...11,523,695
Ensembl chrNW_004936489:11,447,038...11,524,174
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Ikzf1 |
IKAROS family zinc finger 1 |
exacerbates ameliorates |
ISO |
protein:increased expression:lung (human) mRNA:increased expression:lung (human) |
RGD |
PMID:32787735 PMID:33738286 |
RGD:150540324 RGD:151347632 |
NCBI chrNW_004936686:1,459,582...1,556,478
Ensembl chrNW_004936686:1,462,145...1,556,451
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Il1r2 |
interleukin 1 receptor type 2 |
severity disease_progression |
ISO |
mRNA:increased expression:lung (human) mRNA:altered expression:lung (human) |
RGD |
PMID:29942094 PMID:31921619 |
RGD:152998982 RGD:152998998 |
NCBI chrNW_004936713:679,680...716,801
Ensembl chrNW_004936713:701,155...716,650
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Impdh2 |
inosine monophosphate dehydrogenase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936529:748,777...753,582
Ensembl chrNW_004936529:745,511...753,581
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Ipo4 |
importin 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936722:359,741...370,514
Ensembl chrNW_004936722:360,250...373,400
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Ipo5 |
importin 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936472:12,231,970...12,271,639
Ensembl chrNW_004936472:12,229,922...12,271,964
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Iqsec1 |
IQ motif and Sec7 domain ArfGEF 1 |
disease_progression |
ISO |
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RGD |
PMID:24902879 |
RGD:153350085 |
NCBI chrNW_004936898:318,564...425,785
Ensembl chrNW_004936898:337,400...425,859
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Irak3 |
interleukin 1 receptor associated kinase 3 |
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ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:21278795 |
RGD:36049796 |
NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
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Ireb2 |
iron responsive element binding protein 2 |
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ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636
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Jak2 |
Janus kinase 2 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:27025877 |
RGD:11574134 |
NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
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Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24366584 |
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NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123
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Kcnj4 |
potassium inwardly rectifying channel subfamily J member 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30512237 |
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NCBI chrNW_004936492:2,865,803...2,867,657
Ensembl chrNW_004936492:2,865,879...2,867,201
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Klf5 |
KLF transcription factor 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936511:7,806,714...7,824,833
Ensembl chrNW_004936511:7,806,708...7,824,992
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Kmt2c |
lysine methyltransferase 2C |
onset disease_progression |
ISO |
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RGD |
PMID:30821106 PMID:32867667 |
RGD:151356760 RGD:151356761 |
NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365
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Kpna2 |
karyopherin subunit alpha 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936541:5,217,389...5,228,816
Ensembl chrNW_004936541:5,217,362...5,228,846
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Kras |
KRAS proto-oncogene, GTPase |
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ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:2278970 PMID:3122217 PMID:6320174 PMID:11745231 PMID:12460918 PMID:15696205 PMID:16051643 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17384584 PMID:17704260 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19679400 PMID:19773371 PMID:19794967 PMID:20921462 PMID:20921465 PMID:21228335 PMID:21975775 PMID:22282465 PMID:22407852 PMID:22722830 PMID:23014527 PMID:23182985 PMID:23325582 PMID:23406027 PMID:25044103 PMID:25157968 PMID:26242988 PMID:26619011 PMID:28492532 PMID:31666701 PMID:35658005 More...
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NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
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Ldha |
lactate dehydrogenase A |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936528:866,607...879,977
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Lect2 |
leukocyte cell derived chemotaxin 2 |
ameliorates |
ISO |
human cells in mouse model |
RGD |
PMID:30453282 |
RGD:153323337 |
NCBI chrNW_004936597:3,051,143...3,057,383
Ensembl chrNW_004936597:3,051,143...3,057,383
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Lmna |
lamin A/C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936580:5,374,208...5,395,442
Ensembl chrNW_004936580:5,373,974...5,395,468
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Lmnb1 |
lamin B1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936504:157,459...211,916
Ensembl chrNW_004936504:157,453...211,967
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LOC101957714 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
ameliorates |
ISO |
DNA:hypomethylation:promoter (human) mRNA:decreased expression:lung (human) human cell line in a mouse model |
RGD |
PMID:24736069 PMID:25519225 PMID:27793774 |
RGD:151361181 RGD:151665173 RGD:151665499 |
NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
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LOC101959095 |
RNA polymerase I and III subunit D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936472:22,841,094...22,842,798
Ensembl chrNW_004936472:22,841,094...22,881,713
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LOC101970101 |
cytochrome P450 1B1 |
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ISO |
protein:increased expression:lung (human) |
RGD |
PMID:19358281 |
RGD:152177688 |
NCBI chrNW_004936663:345,021...355,188
Ensembl chrNW_004936663:348,368...355,191
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LOC101970831 |
serotransferrin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936529:6,917,762...6,947,512
Ensembl chrNW_004936529:6,855,958...6,947,394
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LOC101975532 |
delta-1-pyrroline-5-carboxylate synthase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936636:3,779,259...3,800,846
Ensembl chrNW_004936636:3,760,326...3,801,073
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G |
Lrp1b |
LDL receptor related protein 1B |
disease_progression |
ISO |
DNA:mutations:multiple: (human) |
RGD |
PMID:18948947 |
RGD:11064706 |
NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283
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Lrrc56 |
leucine rich repeat containing 56 |
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ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17601930 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20937837 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22420426 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25695684 PMID:25741868 PMID:25815234 PMID:25914166 PMID:26467025 PMID:26619011 PMID:26778095 PMID:27195699 PMID:27283355 PMID:27444071 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28328122 PMID:28492532 PMID:29493581 PMID:30055033 PMID:30138938 PMID:30191474 PMID:31394527 PMID:31560489 PMID:31564432 PMID:31775759 PMID:32165824 PMID:32371413 PMID:32732226 PMID:33027564 PMID:33372952 PMID:34008892 PMID:34958143 PMID:168335863 More...
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NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
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Map2k1 |
mitogen-activated protein kinase kinase 1 |
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ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung (human) |
ClinVar CTD RGD |
PMID:22135231 PMID:26619011 PMID:29254206 |
RGD:151665107 |
NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
severity |
ISO |
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RGD |
PMID:12231543 PMID:21896780 |
RGD:150429783 RGD:150429821 |
NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662
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Map2k7 |
mitogen-activated protein kinase kinase 7 |
exacerbates |
ISO |
human gene in a mouse model |
RGD |
PMID:34236045 |
RGD:155230828 |
NCBI chrNW_004936588:4,882,191...4,891,807
Ensembl chrNW_004936588:4,882,184...4,892,071
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Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
exacerbates |
ISO |
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RGD |
PMID:23533274 |
RGD:151356978 |
NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892
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Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
exacerbates ameliorates |
ISO |
mRNA, protein:increased expression:lung (human) human cell line in a mouse model |
RGD |
PMID:22824148 PMID:28306189 PMID:33510968 |
RGD:151347677 RGD:151347678 RGD:151347681 |
NCBI chrNW_004936713:515,388...616,024
Ensembl chrNW_004936713:435,238...612,835
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Mapk14 |
mitogen-activated protein kinase 14 |
exacerbates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:31969449 |
RGD:151665505 |
NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232
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Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
severity treatment |
ISO |
mRNA:increased expression:lung (human) human cells in mouse model |
RGD |
PMID:31200834 |
RGD:151356911 |
NCBI chrNW_004936580:803,452...806,966
Ensembl chrNW_004936580:804,903...806,796
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Meox1 |
mesenchyme homeobox 1 |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:34837450 |
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NCBI chrNW_004936541:216,390...238,153
Ensembl chrNW_004936541:217,193...236,031
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Mier3 |
MIER family member 3 |
ameliorates |
ISO |
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RGD |
PMID:35117188 |
RGD:407571696 |
NCBI chrNW_004936480:11,001,964...11,031,891
Ensembl chrNW_004936480:11,002,583...11,032,329
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Mki67 |
marker of proliferation Ki-67 |
disease_progression |
ISO |
protein:altered expression:lung (human) |
RGD |
PMID:26942465 |
RGD:152999419 |
NCBI chrNW_004936486:15,561,327...15,587,109
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Mlh1 |
mutL homolog 1 |
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ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
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Mre11 |
MRE11 homolog, double strand break repair nuclease |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936674:466,495...528,072
Ensembl chrNW_004936674:466,456...530,317
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Mrpl12 |
mitochondrial ribosomal protein L12 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936594:5,301,846...5,305,362
Ensembl chrNW_004936594:5,301,866...5,305,362
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G |
Mrps5 |
mitochondrial ribosomal protein S5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004937185:25,998...39,685
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G |
Ms4a1 |
membrane spanning 4-domains A1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22514692 |
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NCBI chrNW_004936581:2,466,294...2,477,530
Ensembl chrNW_004936581:2,466,312...2,477,530
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Msh2 |
mutS homolog 2 |
no_association |
ISO |
DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human) DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human) |
RGD |
PMID:16614121 |
RGD:11065547 |
NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
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Msh3 |
mutS homolog 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21327329 |
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NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561
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G |
Msh6 |
mutS homolog 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21327329 |
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NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787
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G |
Muc1 |
mucin 1, cell surface associated |
|
ISO |
mRNA:increased expression:lung |
RGD |
PMID:8694545 |
RGD:5131260 |
NCBI chrNW_004936580:4,691,870...4,694,092
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Muc4 |
mucin 4, cell surface associated |
disease_progression |
ISO |
protein:increased expression:trachea |
RGD |
PMID:17126950 |
RGD:5131208 |
NCBI chrNW_004936784:515,608...539,915
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
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ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936816:129,926...159,396
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
|
ISO |
human cell line in mouse model CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:20033209 PMID:26656844 PMID:27602772 |
RGD:7207787 |
NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965
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G |
Myd88 |
MYD88 innate immune signal transduction adaptor |
ameliorates treatment |
ISO |
mouse cell line in a mouse model |
RGD |
PMID:30712876 PMID:32140881 |
RGD:150520172 RGD:150540309 |
NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
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G |
Naa10 |
N-alpha-acetyltransferase 10, NatA catalytic subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936809:812,454...817,226
Ensembl chrNW_004936809:812,390...817,288
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G |
Naip |
NLR family apoptosis inhibitory protein |
ameliorates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:31964418 |
RGD:153344516 |
NCBI chrNW_004936549:5,000,526...5,069,110
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G |
Ncapg |
non-SMC condensin I complex subunit G |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34419073 |
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NCBI chrNW_004936477:10,408,347...10,445,361
Ensembl chrNW_004936477:10,405,997...10,445,206
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G |
Nkx2-1 |
NK2 homeobox 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566
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G |
Nlrp3 |
NLR family pyrin domain containing 3 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936864:709,693...732,119
Ensembl chrNW_004936864:709,709...731,718
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G |
Nop56 |
NOP56 ribonucleoprotein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936485:16,038,090...16,043,408
Ensembl chrNW_004936485:16,038,182...16,043,357
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G |
Nop58 |
NOP58 ribonucleoprotein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936726:1,457,038...1,487,374
Ensembl chrNW_004936726:1,457,002...1,486,530
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Notch1 |
notch receptor 1 |
treatment |
ISO |
|
RGD |
PMID:33628824 |
RGD:155663482 |
NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428
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Npm1 |
nucleophosmin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936609:3,712,628...3,725,635
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Npm3 |
nucleophosmin/nucleoplasmin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936600:3,997,549...3,999,620
Ensembl chrNW_004936600:3,997,285...3,999,630
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Nudt21 |
nudix hydrolase 21 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936475:8,739,992...8,759,165
Ensembl chrNW_004936475:8,741,821...8,759,223
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Nuf2 |
NUF2 component of NDC80 kinetochore complex |
disease_progression |
ISO |
|
RGD |
PMID:32226507 |
RGD:28912743 |
NCBI chrNW_004936481:21,342,667...21,371,311
Ensembl chrNW_004936481:21,342,786...21,371,328
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Ogg1 |
8-oxoguanine DNA glycosylase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23951099 |
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NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831
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G |
Pabpc4 |
poly(A) binding protein cytoplasmic 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936474:21,453,244...21,468,059
Ensembl chrNW_004936474:21,452,005...21,468,065
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Pacrg |
parkin coregulated |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:12719539 |
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NCBI chrNW_004936489:13,328,143...13,787,329
Ensembl chrNW_004936489:13,328,078...13,787,344
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G |
Pcbd1 |
pterin-4 alpha-carbinolamine dehydratase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936521:7,843,945...7,847,827
Ensembl chrNW_004936521:7,845,870...7,848,426
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Pign |
phosphatidylinositol glycan anchor biosynthesis class N |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936497:3,121,184...3,230,912
Ensembl chrNW_004936497:3,124,557...3,234,061
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Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 PMID:15805248 PMID:15930273 PMID:16906227 PMID:16930767 PMID:17376864 PMID:17673550 PMID:18074223 PMID:18676830 PMID:18725974 PMID:19029981 PMID:19223544 PMID:19366826 PMID:19513541 PMID:19903786 PMID:20453058 PMID:20581867 PMID:20593314 PMID:20619739 PMID:21078999 PMID:21430269 PMID:21558396 PMID:21824802 PMID:22162582 PMID:22162589 PMID:22209294 PMID:22271473 PMID:22357840 PMID:22370636 PMID:22658544 PMID:22729222 PMID:22729223 PMID:22729224 PMID:23066039 PMID:23100325 PMID:23408298 PMID:23888070 PMID:23946963 PMID:24033266 PMID:24265155 PMID:24497998 PMID:24559322 PMID:24782230 PMID:25157968 PMID:25599672 PMID:25741868 PMID:25880439 PMID:25915946 PMID:26266975 PMID:26266985 PMID:26351730 PMID:26619011 PMID:26627007 PMID:26637981 PMID:26822237 PMID:26851524 PMID:27126994 PMID:27626068 PMID:27631024 PMID:28151489 PMID:28425981 PMID:28492532 PMID:28941273 PMID:29446767 PMID:29549527 PMID:29661094 PMID:29758562 PMID:29988677 PMID:30063105 PMID:30376034 PMID:30543347 PMID:31536475 PMID:31775759 PMID:32778138 PMID:34008892 PMID:34496175 PMID:37712948 More...
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NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
|
ISO |
mRNA:decreased expression:lung |
RGD |
PMID:26695082 |
RGD:13464334 |
NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537
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G |
Pitx2 |
paired like homeodomain 2 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936563:1,713,294...1,732,431
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Plcg1 |
phospholipase C gamma 1 |
exacerbates |
ISO |
protein:decreased expression:lung (human) |
RGD |
PMID:33077911 |
RGD:151356960 |
NCBI chrNW_004936561:598,372...631,575
Ensembl chrNW_004936561:598,382...631,581
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Plod2 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 |
disease_progression |
ISO |
|
RGD |
PMID:29072684 |
RGD:151665822 |
NCBI chrNW_004936519:9,053,192...9,139,221
Ensembl chrNW_004936519:9,053,033...9,140,059
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G |
Pold1 |
DNA polymerase delta 1, catalytic subunit |
exacerbates |
ISO |
protein:increased expression:lung (human) |
RGD |
PMID:33442399 |
RGD:153323317 |
NCBI chrNW_004936889:231,373...250,985
Ensembl chrNW_004936889:231,373...250,987 Ensembl chrNW_004936889:231,373...250,987
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Ppan |
peter pan homolog |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936659:499,447...503,316
Ensembl chrNW_004936659:499,536...503,162
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540
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G |
Prame |
PRAME nuclear receptor transcriptional regulator |
|
ISO |
mRNA:decreased expression:lung (human) |
RGD |
PMID:27241212 |
RGD:11535020 |
NCBI chrNW_004936619:1,748,337...1,751,748
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Prdm1 |
PR/SET domain 1 |
exacerbates |
ISO |
|
RGD |
PMID:28378641 |
RGD:150530469 |
NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:10072423 PMID:12719539 PMID:20301651 PMID:22956510 PMID:25741868 PMID:28492532 PMID:32647592 More...
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NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872
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G |
Psat1 |
phosphoserine aminotransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936632:4,392,165...4,422,670
Ensembl chrNW_004936632:4,391,459...4,423,264
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G |
Ptch1 |
patched 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 PMID:28492532 |
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NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476
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G |
Pten |
phosphatase and tensin homolog |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
|
NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
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G |
Ptpn13 |
protein tyrosine phosphatase non-receptor type 13 |
exacerbates susceptibility |
ISO |
mRNA,protein:decreased expression:lung DNA:missense mutations:cds:p.I1522M, p.Y2081D (human) |
RGD |
PMID:19672627 PMID:22245727 PMID:33536603 |
RGD:152176663 RGD:152176665 RGD:152975626 |
NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001
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G |
Ptprb |
protein tyrosine phosphatase receptor type B |
disease_progression |
ISO |
mRNA:altered expression:lung (human) mRNA:decreased expression:lung (human) |
RGD |
PMID:7981622 PMID:29254206 |
RGD:151665107 RGD:151665112 |
NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715
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G |
Ptprj |
protein tyrosine phosphatase receptor type J |
susceptibility |
ISO |
DNA:missense mutations:cds:p.R326Q, p.Q276P (human) |
RGD |
PMID:19672627 |
RGD:152176665 |
NCBI chrNW_004936562:1,161,764...1,234,800
Ensembl chrNW_004936562:1,165,304...1,211,817
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G |
Rac1 |
Rac family small GTPase 1 |
exacerbates ameliorates |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:31779616 PMID:32366477 |
RGD:152998910 RGD:153345550 |
NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 PMID:17603483 PMID:19568997 PMID:19953625 PMID:20052757 PMID:20301557 PMID:21440552 PMID:21784453 PMID:22389993 PMID:23312806 PMID:23321623 PMID:23877478 PMID:24033266 PMID:24775816 PMID:25706034 PMID:25741868 PMID:26619011 PMID:26918529 PMID:27631234 PMID:28492532 PMID:28973083 PMID:28991257 PMID:29084544 PMID:29493581 PMID:30105547 PMID:30138938 PMID:30384889 PMID:31560489 PMID:32573669 PMID:33240318 More...
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NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096
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G |
Rangrf |
RAN guanine nucleotide release factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936595:1,513,855...1,515,300
Ensembl chrNW_004936595:1,513,180...1,517,270
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G |
Rarb |
retinoic acid receptor beta |
|
ISO |
DNA:hypomethylation:lung |
RGD |
PMID:26695082 |
RGD:13464334 |
NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885
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G |
Rasa1 |
RAS p21 protein activator 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
|
NCBI chrNW_004936469:5,839,560...5,933,049
Ensembl chrNW_004936469:5,839,743...5,932,021
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G |
Rb1 |
RB transcriptional corepressor 1 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846
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G |
Rbm10 |
RNA binding motif protein 10 |
|
ISO |
mRNA, protein:decreased expression:lung DNA:missense mutations, protein-truncating variants: :multiple |
RGD |
PMID:22980975 PMID:29085465 PMID:30955253 |
RGD:11097386 RGD:151356983 RGD:151356984 |
NCBI chrNW_004936502:12,923,890...12,952,179
Ensembl chrNW_004936502:12,925,910...12,955,470
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G |
Rcl1 |
RNA terminal phosphate cyclase like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936503:375,191...450,596
Ensembl chrNW_004936503:373,934...450,596
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G |
Rfc4 |
replication factor C subunit 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936578:3,204,035...3,219,806
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G |
Rin3 |
Ras and Rab interactor 3 |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936733:683,309...765,897
Ensembl chrNW_004936733:683,272...765,906
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G |
Rnaseh2a |
ribonuclease H2 subunit A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34254728 |
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NCBI chrNW_004936659:1,897,777...1,905,526
Ensembl chrNW_004936659:1,897,769...1,905,457
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G |
Rnf43 |
ring finger protein 43 |
severity |
ISO |
human cells in a mouse model |
RGD |
PMID:31286874 |
RGD:151361222 |
NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828
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G |
Ros1 |
ROS proto-oncogene 1, receptor tyrosine kinase |
|
ISO |
ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:27993330 |
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NCBI chrNW_004936658:382,025...506,818
Ensembl chrNW_004936658:382,261...506,818
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G |
Rpl10a |
ribosomal protein L10a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936476:23,779,144...23,781,560
Ensembl chrNW_004936476:23,779,140...23,781,563
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G |
Rpl13a |
ribosomal protein L13a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936664:3,352,535...3,356,196
Ensembl chrNW_004936664:3,352,514...3,356,895
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G |
Rpl27a |
ribosomal protein L27a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936528:9,343,620...9,348,935
Ensembl chrNW_004936528:9,346,592...9,348,482
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G |
Rpl36a |
ribosomal protein L36a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936813:467,505...470,673
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G |
Rpsa |
ribosomal protein SA |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936473:28,624,110...28,628,488
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G |
Rrm1 |
ribonucleotide reductase catalytic subunit M1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793
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G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936532:6,348,041...6,390,144
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G |
Rrs1 |
ribosome biogenesis regulator 1 homolog |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936496:7,563,989...7,565,663
Ensembl chrNW_004936496:7,564,459...7,565,556
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G |
Satb1 |
SATB homeobox 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936473:10,906,059...11,001,007
Ensembl chrNW_004936473:10,904,989...11,001,051
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G |
Sdc1 |
syndecan 1 |
|
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:23374247 |
RGD:151708716 |
NCBI chrNW_004936493:11,177,804...11,199,678
Ensembl chrNW_004936493:11,177,708...11,199,804
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G |
Serpina3 |
serpin family A member 3 |
|
ISO |
protein:increased expression:cytoplasm |
RGD |
PMID:8620411 |
RGD:5147446 |
NCBI chrNW_004936846:174,411...182,053
Ensembl chrNW_004936846:174,233...182,203
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G |
Setd2 |
SET domain containing 2, histone lysine methyltransferase |
ameliorates exacerbates severity |
ISO |
human cells and genes in mouse model DNA:mutations:multiple (human) |
RGD |
PMID:27687306 PMID:28202515 PMID:33223508 PMID:33707235 |
RGD:126848875 RGD:150429633 RGD:150429648 RGD:150429649 |
NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373
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Sfn |
stratifin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433
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G |
Sftpc |
surfactant protein C |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25851810 |
|
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
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G |
Sfxn1 |
sideroflexin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936609:727,621...754,806
Ensembl chrNW_004936609:729,589...754,774
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G |
Shmt1 |
serine hydroxymethyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936741:1,849,239...1,877,724
Ensembl chrNW_004936741:1,849,609...1,877,727
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G |
Slc15a2 |
solute carrier family 15 member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
|
NCBI chrNW_004936536:8,280,537...8,316,011
Ensembl chrNW_004936536:8,280,448...8,316,064
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G |
Slc19a1 |
solute carrier family 19 member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936778:823,376...846,843
Ensembl chrNW_004936778:829,550...848,833
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Slc1a5 |
solute carrier family 1 member 5 |
disease_progression |
ISO |
|
RGD |
PMID:26279756 |
RGD:151361150 |
NCBI chrNW_004936664:599,012...610,689
Ensembl chrNW_004936664:598,468...610,698
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Slc3a2 |
solute carrier family 3 member 2 |
disease_progression |
ISO |
|
RGD |
PMID:19171406 |
RGD:151361151 |
NCBI chrNW_004936581:424,801...441,592
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G |
Slc4a4 |
solute carrier family 4 member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936598:3,391,587...3,713,629
Ensembl chrNW_004936598:3,391,575...3,713,635
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G |
Slc4a7 |
solute carrier family 4 member 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936473:18,550,489...18,645,470
Ensembl chrNW_004936473:18,550,484...18,645,628
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Slc67a1 |
solute carrier family 67 member 1 |
disease_progression |
ISO |
mRNA:increased expression:lung (human) ClinVar Annotator: match by term: Lung adenocarcinoma |
RGD ClinVar |
PMID:27993330 PMID:32726996 |
RGD:150557423 |
NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345
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Slc7a5 |
solute carrier family 7 member 5 |
disease_progression |
ISO |
|
RGD |
PMID:19171406 PMID:26279756 |
RGD:151361150 RGD:151361151 |
NCBI chrNW_004936641:1,513,110...1,538,955
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G |
Smad4 |
SMAD family member 4 |
|
ISO |
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma |
ClinVar |
PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 PMID:9679244 PMID:9811934 PMID:10479724 PMID:10764709 PMID:10775259 PMID:10797267 PMID:11274206 PMID:11583957 PMID:12116240 PMID:12821112 PMID:14715079 PMID:15014009 PMID:15031030 PMID:15235019 PMID:16613914 PMID:17873119 PMID:17994767 PMID:18823382 PMID:20101697 PMID:20301642 PMID:22316667 PMID:22331366 PMID:25741868 PMID:26572829 PMID:26619011 PMID:26900293 PMID:27595937 PMID:28492532 PMID:31837202 PMID:32300199 PMID:32573726 PMID:32944796 More...
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NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123
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G |
Smarcc1 |
SWI/SNF related BAF chromatin remodeling complex subunit C1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038
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G |
Snrpb |
small nuclear ribonucleoprotein polypeptides B and B1 |
severity |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:22876301 |
RGD:10768834 |
NCBI chrNW_004936485:16,142,231...16,161,761
Ensembl chrNW_004936485:16,157,485...16,163,698
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G |
Snrpe |
small nuclear ribonucleoprotein polypeptide E |
severity |
ISO |
mRNA:increased expression:lung (human) |
RGD |
PMID:22876301 |
RGD:10768834 |
NCBI chrNW_004936567:849,300...855,214
Ensembl chrNW_004936567:849,397...855,187
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G |
Snrpg |
small nuclear ribonucleoprotein polypeptide G |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936491:14,442,904...14,450,717
Ensembl chrNW_004936491:14,443,026...14,450,631
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G |
Sod2 |
superoxide dismutase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
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NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
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G |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27158780 |
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NCBI chrNW_004936508:12,162,553...12,281,812
Ensembl chrNW_004936508:12,162,547...12,281,820
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G |
Sox2 |
SRY-box transcription factor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25184679 |
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NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613
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G |
Sox30 |
SRY-box transcription factor 30 |
disease_progression |
ISO |
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RGD |
PMID:26330328 |
RGD:11535423 |
NCBI chrNW_004936515:5,501,315...5,537,946
Ensembl chrNW_004936515:5,458,393...5,537,946
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G |
Spop |
speckle type BTB/POZ protein |
ameliorates |
ISO |
human gene and cell line in mouse model mRNA, protein:increased expression:lung (human) |
RGD |
PMID:30607139 PMID:31105033 |
RGD:153298920 RGD:153298927 |
NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
severity |
ISO |
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RGD |
PMID:12826049 |
RGD:150521546 |
NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483
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G |
Srm |
spermidine synthase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27602772 |
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NCBI chrNW_004936474:121,135...124,894
Ensembl chrNW_004936474:118,000...124,963
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G |
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