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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:ovary adenocarcinoma
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Accession:DOID:3713 term browser browse the term
Definition:An ovarian carcinoma that derives_from epithelial cells of glandular origin. (DO)
Synonyms:exact_synonym: ovarian adenoacanthoma;   ovarian adenocarcinoma
 related_synonym: adenocarcinoma of the ovary
 primary_id: RDO:9002507
 xref: EFO:0006460;   NCI:C129858;   NCI:C7700
For additional species annotation, visit the Alliance of Genome Resources.


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ovary adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd3 cyclin D3 disease_progression ISO RGD PMID:17885491 RGD:2316011 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ISO mRNA:increased expression:ovary (human) RGD PMID:16180015 RGD:151361183 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Ovarian adenocarcinoma ClinVar PMID:15457249 PMID:18339846 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Pramex1 PRAME like, X-linked 1 severity ISO mRNA, protein:increased expression:female gonad (human) RGD PMID:18709641 RGD:11535054 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096 		JBrowse link
ovarian serous cystadenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:26619011 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates ISO mRNA:increased expression:ovary (human) RGD PMID:31964418 RGD:153344516 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:24033266 PMID:24446311 PMID:25157968 PMID:25741868 PMID:26619011 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:22908275 PMID:26619011 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More... NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
ovary serous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A ISO ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary ClinVar NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma ClinVar PMID:16084575 PMID:16455195 PMID:16949048 PMID:17100994 PMID:19656164 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma ClinVar PMID:16793542 PMID:18704680 PMID:25741868 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Bsg basigin (Ok blood group) ISO protein:increased expression:ovary RGD PMID:16633062 RGD:2289053 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary ClinVar PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 More... NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Tp53 tumor protein p53 ISO DNA, protein:loss of heterozygosity, increased expression:ovary RGD PMID:1310251 RGD:2290540 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    disease of cellular proliferation 7667
      cancer 5483
        cell type cancer 3731
          carcinoma 3200
            adenocarcinoma 1713
              ovary adenocarcinoma 19
                endometrioid ovary carcinoma 0
                ovarian clear cell adenocarcinoma 0
                ovarian cystadenocarcinoma + 11
                ovarian mucinous adenocarcinoma 0
                ovary serous adenocarcinoma + 16
                rete ovarii adenocarcinoma 0
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18212
      Urogenital Diseases 5216
        Female Urogenital Diseases and Pregnancy Complications 2432
          Female Urogenital Diseases 1981
            female reproductive system disease 1978
              Adnexal Diseases 903
                ovarian disease 894
                  Ovarian Neoplasms 580
                    ovarian cancer 456
                      ovary epithelial cancer 127
                        malignant ovarian surface epithelial-stromal neoplasm 103
                          ovarian carcinoma 103
                            ovary adenocarcinoma 19
                              endometrioid ovary carcinoma 0
                              ovarian clear cell adenocarcinoma 0
                              ovarian cystadenocarcinoma + 11
                              ovarian mucinous adenocarcinoma 0
                              ovary serous adenocarcinoma + 16
                              rete ovarii adenocarcinoma 0
paths to the root