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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Sertoli cell tumor
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Accession:DOID:3577 term browser browse the term
Definition:A sex cord-gonadal stromal tumor characterized by excessive proliferation of Sertoli cells. (DO)
Synonyms:exact_synonym: tubular androblastoma
 narrow_synonym: Testicular Large Cell Calcifying Sertoli Cell Tumor;   Testicular Sclerosing Sertoli Cell Tumor;   Testicular Sertoli Cell Tumor
 primary_id: MESH:D012707
 alt_id: DOID:0050617
 xref: EFO:1000568;   EFO:1000571;   EFO:1000572;   NCI:C39976
For additional species annotation, visit the Alliance of Genome Resources.


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Sertoli cell tumor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inha inhibin subunit alpha ISO reexpression in tumor derived cells eliminates the transformed phenotype RGD PMID:10602485 RGD:2290369 NCBI chrNW_004936569:1,949,747...1,954,179
Ensembl chrNW_004936569:1,950,297...1,954,165
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    disease of cellular proliferation 6811
      Neoplasms by Histologic Type 4727
        Gonadal Tissue Neoplasms 135
          sex cord-gonadal stromal tumor 36
            Sertoli cell tumor 1
Path 2
Term Annotations click to browse term
  disease 16465
    disease of anatomical entity 14117
      Urogenital Diseases 4491
        reproductive system disease 2779
          reproductive system neoplasm 1186
            reproductive organ cancer 1172
              sex cord-gonadal stromal tumor 36
                Sertoli cell tumor 1
paths to the root