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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:sagittal sinus thrombosis
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Accession:DOID:3576 term browser browse the term
Definition:Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.
Synonyms:exact_synonym: Sagittal Sinus Septic Phlebitis;   Sagittal Sinus Thrombophlebitis;   Sagittal Sinus Thromboses;   Thrombosis of superior longitudinal sinus;   Thrombosis of superior sagittal sinus
 primary_id: MESH:D020225;   RDO:0007361
For additional species annotation, visit the Alliance of Genome Resources.


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sagittal sinus thrombosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F5 coagulation factor V ISO CTD Direct Evidence: marker/mechanism CTD PMID:18382986 NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296 		JBrowse link
G PLAU plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:10668740 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PROS1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:18382986 NCBI chr33:1,628,074...1,691,441
Ensembl chr33:1,628,105...1,692,058 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17773
    disease of anatomical entity 15145
      cardiovascular system disease 4407
        vascular disease 3103
          cerebrovascular disease 951
            intracranial thrombosis 20
              intracranial sinus thrombosis 6
                sagittal sinus thrombosis 3
Path 2
Term Annotations click to browse term
  disease 17773
    disease of anatomical entity 15145
      cardiovascular system disease 4407
        vascular disease 3103
          Embolism and Thrombosis 161
            Thromboembolism 50
              Intracranial Embolism and Thrombosis 21
                intracranial thrombosis 20
                  intracranial sinus thrombosis 6
                    sagittal sinus thrombosis 3
paths to the root