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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:plague
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Accession:DOID:3482 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food. (DO)
Synonyms:exact_synonym: Black Plague;   Meningeal Plague;   Meningeal Plagues;   Pulmonic Plague;   Yersinia pestis infections;   Yersinia pestis infectious disease;   black plagues;   pulmonic plagues
 related_synonym: N-FORMYLPEPTIDE RECEPTOR POLYMORPHISM
 primary_id: MESH:D010930
 xref: EFO:0009425;   ICD10CM:A20;   ICD9CM:020;   NCI:C85015
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
plague term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr5 C-C motif chemokine receptor 5 resistance IAGP DNA:polymorphism:cds:p.H184R (rat) RGD PMID:18703167 RGD:4890425 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO RGD PMID:21356370 RGD:5134954 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Fpr1 formyl peptide receptor 1 ISO ClinVar Annotator: match by term: N-FORMYLPEPTIDE RECEPTOR POLYMORPHISM ClinVar PMID:25741868 PMID:28492532 PMID:31534221 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559
JBrowse link
G Il17a interleukin 17A IEP mRNA,protein:increased expression:lymph node RGD PMID:20876291 RGD:4781452 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:20565713 RGD:4142820 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mavs mitochondrial antiviral signaling protein susceptibility ISO RGD PMID:25064677 RGD:40903046 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    disease by infectious agent 2252
      Bacterial Infections and Mycoses 1118
        bacterial infectious disease 824
          primary bacterial infectious disease 198
            plague 6
              bubonic plague 0
              pneumonic plague 0
              septicemic plague 0
Path 2
Term Annotations click to browse term
  disease 19134
    disease by infectious agent 2252
      Bacterial Infections and Mycoses 1118
        bacterial infectious disease 824
          Gram-Negative Bacterial Infections 200
            Enterobacteriaceae Infections 47
              Yersinia Infections 6
                plague 6
                  bubonic plague 0
                  pneumonic plague 0
                  septicemic plague 0
paths to the root