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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:uterine disease
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Accession:DOID:345 term browser browse the term
Definition:Pathological processes involving any part of the UTERUS.
Synonyms:exact_synonym: uterine diseases
 primary_id: MESH:D014591
 alt_id: RDO:0004098
 xref: ICD10CM:N85.9;   ICD9CM:621.9;   NCI:C26907
For additional species annotation, visit the Alliance of Genome Resources.


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uterine disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide ISO CTD Direct Evidence: therapeutic CTD PMID:20146381 NCBI chrNW_004936510:4,679,349...4,696,511 JBrowse link
adhesions of uterus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor treatment
severity
ISO mRNA, protein:increased expression:endometrium RGD PMID:31596310 RGD:126925216 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA, protein:increased expression:endometrium RGD PMID:31596310 RGD:126925216 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
anogenital venereal wart term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 ISO protein:decreased expression:skin RGD PMID:17545018 RGD:7483603 NCBI chrNW_004936525:8,238,128...8,240,974 JBrowse link
G Cd8a CD8a molecule ISO mRNA:decreased expression:zone of skin (human) RGD PMID:25774455 RGD:36174028 NCBI chrNW_004936712:885,301...891,247 JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936631:484,356...489,643 JBrowse link
G Foxp3 forkhead box P3 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il10 interleukin 10 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il12b interleukin 12B treatment ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:16114559 PMID:23754510 RGD:40400714 RGD:7829774 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il2 interleukin 2 ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il6 interleukin 6 ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936473:27,672,237...27,676,339 JBrowse link
G Pdcd1 programmed cell death 1 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936745:152,571...163,712 JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Serpinf1 serpin family F member 1 disease_progression ISO mRNA, protein:decreased expression:skin of body (human) RGD PMID:23569025 RGD:27226706 NCBI chrNW_004936538:7,885,816...7,898,308 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tlr2 toll like receptor 2 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tlr3 toll like receptor 3 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Tlr4 toll like receptor 4 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tlr7 toll like receptor 7 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936470:2,593,544...2,610,972 JBrowse link
G Tlr8 toll like receptor 8 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936470:2,638,020...2,642,201 JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chrNW_004936737:1,905,307...1,910,356 JBrowse link
cervical adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink1 serine peptidase inhibitor Kazal type 1 ISO RGD PMID:2258083 RGD:2300391 NCBI chrNW_004936504:6,975,044...6,981,304 JBrowse link
G Tfrc transferrin receptor ISO protein:increased expression:uterine cervix RGD PMID:9739406 RGD:2292022 NCBI chrNW_004936784:696,738...728,385 JBrowse link
G Tp53 tumor protein p53 disease_progression ISO RGD PMID:17354237 RGD:2298527 NCBI chrNW_004936595:919,807...935,367 JBrowse link
cervical cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin ISO protein:increased expression:serum RGD PMID:11299848 RGD:2325708 NCBI chrNW_004936880:39,372...40,070 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO DNA:polymorphism: :p.D148E (human) RGD PMID:18503157 PMID:19292061 RGD:2315657 RGD:2315662 NCBI chrNW_004936877:666,545...669,351 JBrowse link
G Api5 apoptosis inhibitor 5 disease_progression ISO mRNA:increased expression RGD PMID:10780674 RGD:1643340 NCBI chrNW_004936562:5,229,157...5,253,175 JBrowse link
G Bcl2l1 BCL2 like 1 ISO protein:increased expression:uterine cervix RGD PMID:17311011 RGD:1643476 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Birc2 baculoviral IAP repeat containing 2 ISO mRNA:decreased expression:uterine cervix RGD PMID:16504151 RGD:1643527 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Brca1 BRCA1 DNA repair associated disease_progression ISO DNA:hypermethylation:promoter RGD PMID:12773202 RGD:2298941 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brip1 BRCA1 interacting helicase 1 ISO ClinVar Annotator: match by term: Cancer of cervix ClinVar PMID:18483852 PMID:25741868 PMID:26467025 PMID:26790966 PMID:28492532 PMID:31214711 PMID:32566746 NCBI chrNW_004936490:3,001,445...3,139,538 JBrowse link
G Bsg basigin (Ok blood group) disease_progression ISO RGD PMID:18223224 RGD:2296028 NCBI chrNW_004936588:181,688...189,795 JBrowse link
G Casp3 caspase 3 ISO RGD PMID:18177927 RGD:2298948 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Ccnb1 cyclin B1 ISO mRNA, protein:increased expression:uterine cervix RGD PMID:16614707 RGD:2315938 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) ISO RGD PMID:9358772 RGD:2293549 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cdc25a cell division cycle 25A ISO RGD PMID:18299147 RGD:2296067 NCBI chrNW_004936596:1,657,411...1,680,109 JBrowse link
G Cdc25c cell division cycle 25C ISO RGD PMID:15289842 RGD:4105450 NCBI chrNW_004936531:7,471,722...7,499,781 JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation:promoter RGD PMID:17548682 RGD:2293543 NCBI chrNW_004936641:3,925,185...4,223,421 JBrowse link
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:18299147 RGD:2296067 NCBI chrNW_004936614:2,300,682...2,313,611 JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 disease_progression ISO protein:increased expression:uterine cervix RGD PMID:16112176 RGD:2289851 NCBI chrNW_004936470:35,449,920...35,473,635 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO protein:increased expression: uterine cervix, cytoplasm RGD PMID:28042953 RGD:126790468 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Fanca FA complementation group A no_association ISO DNA:SNP: :rs11649196 (human)
DNA:SNPs, haplotypes: :[rs2239359, rs7190823, rs7195066 (human)
RGD PMID:19012493 PMID:21543111 RGD:11344886 RGD:11344901 NCBI chrNW_004936641:281,119...319,796 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Cervical cancer
ClinVar Annotator: match by term: Cancer of cervix
ClinVar PMID:1908846 PMID:7773297 PMID:8589699 PMID:8858131 PMID:9677066 PMID:10073901 PMID:10471491 PMID:10696568 PMID:11038465 PMID:11055896 PMID:11241532 PMID:11529856 PMID:11879084 PMID:12833394 PMID:15772091 PMID:16841094 PMID:17384684 PMID:17875876 PMID:18583390 PMID:18642369 PMID:19381019 PMID:19749790 PMID:25157968 PMID:25606676 PMID:25741868 PMID:25809207 PMID:26619011 PMID:26818779 PMID:28492532 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C ISO protein:increased expression:cervical epithelium (human) RGD PMID:19319956 RGD:10054394 NCBI chrNW_004936880:368,041...425,967 JBrowse link
G Hoxb13 homeobox B13 ISO mRNA:increased expression:uterine cervix RGD PMID:16803519 RGD:2314728 NCBI chrNW_004936490:12,688,572...12,690,908 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO Protein: increased expression RGD PMID:21137014 RGD:6218976 NCBI chrNW_004936542:7,577,192...7,581,598 JBrowse link
G Il10 interleukin 10 disease_progression ISO protein:increased expression:serum RGD PMID:9541628 RGD:2317658 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il1b interleukin 1 beta susceptibility ISO associated with Papillomavirus Infections;DNA:SNP:promoter: -511 C>T (rs16944)(human) RGD PMID:25893807 RGD:36174015 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Kdm3a lysine demethylase 3A severity ISO human gene in a mouse model RGD PMID:23492365 RGD:9590219 NCBI chrNW_004936712:1,053,210...1,097,845 JBrowse link
G Kmt2a lysine methyltransferase 2A ISO human gene in a mouse model RGD PMID:22926525 RGD:9588221 NCBI chrNW_004936542:3,480,071...3,566,823 JBrowse link
G Kmt2e lysine methyltransferase 2E (inactive) ISO human gene in a mouse model RGD PMID:25172963 RGD:9588553 NCBI chrNW_004936479:18,674,657...18,764,177 JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 treatment ISO RGD PMID:20980434 RGD:7495806 NCBI chrNW_004936741:362,682...386,633 JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 ISO mRNA, protein:increased expression:uterine cervix (human) RGD PMID:21853275 RGD:9589052 NCBI chrNW_004936837:363,870...379,406 JBrowse link
G Med4 mediator complex subunit 4 severity ISO mRNA:decreased expression:uterine cervix (human) RGD PMID:19911042 RGD:12880436 NCBI chrNW_004936565:1,397,434...1,414,674 JBrowse link
G Mmp1 matrix metallopeptidase 1 disease_progression ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:14550952 RGD:7207024 NCBI chrNW_004936551:5,167,909...5,175,149 JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO mRNA:increased expression:uterine cervix RGD PMID:17243165 RGD:2306082 NCBI chrNW_004936551:5,040,084...5,050,384 JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:missense mutation:cds:g.1298A>C (human) RGD PMID:27771518 RGD:38501051 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 disease_progression ISO DNA, mRNA:amplification, increased expression:uterine cervix RGD PMID:18559093 RGD:2302384 NCBI chrNW_004936815:144,994...157,788 JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO mRNA:increased expression:uterine cervix RGD PMID:14984964 RGD:2314838 NCBI chrNW_004936627:73,413...82,590 JBrowse link
G Pgm3 phosphoglucomutase 3 ISO RGD PMID:508567 RGD:2299870 NCBI chrNW_004936510:7,586,817...7,622,586 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase disease_progression ISO protein:decreased expression:uterine cervix (human) RGD PMID:28631565 RGD:13432557 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Ptk2 protein tyrosine kinase 2 disease_progression ISO RGD PMID:16638855 RGD:2292556 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Rassf1 Ras association domain family member 1 ISO associated with Papillomavirus Infections;DNA:hypermethylation:promoter RGD PMID:18608185 RGD:2299861 NCBI chrNW_004936529:1,857,177...1,866,198 JBrowse link
G Smad2 SMAD family member 2 ISO DNA, mRNA:insertion, deletion, decreased expression:uterine cervix RGD PMID:12894231 RGD:2299968 NCBI chrNW_004936497:14,723,199...14,812,160 JBrowse link
G Smad4 SMAD family member 4 ISO mRNA:decreased expression:uterine cervix RGD PMID:12894231 RGD:2299968 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO mRNA:increased expression:cervix epithelium (human) RGD PMID:27581326 RGD:13441596 NCBI chrNW_004936508:12,162,553...12,281,812 JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:SNPs: : RGD PMID:12648582 PMID:18248301 RGD:6482260 RGD:6482272 NCBI chrNW_004936476:25,899,514...25,907,690 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:SNPs: : RGD PMID:12648582 PMID:18248301 RGD:6482260 RGD:6482272 NCBI chrNW_004936476:25,913,699...25,923,419 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 disease_progression ISO mRNA:increased expression:uterine cervix RGD PMID:15816637 RGD:2290434 NCBI chrNW_004936602:1,488,993...1,496,108 JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:polymorphism:promoter:-308G>A (human) RGD PMID:19823053 RGD:2315116 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Cervical cancer ClinVar PMID:1349102 PMID:1849234 PMID:25741868 PMID:28492532 PMID:30374176 PMID:30816478 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO DNA:polymorphism: :p.R194W RGD PMID:18851872 RGD:2302567 NCBI chrNW_004936706:752,571...783,746 JBrowse link
G Zfhx3 zinc finger homeobox 3 ISO mRNA:increased expression:uterine cervix RGD PMID:11812077 RGD:2315697 NCBI chrNW_004936475:21,005,242...21,235,992 JBrowse link
cervical mucinous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stk11 serine/threonine kinase 11 disease_progression ISO DNA:mutations RGD PMID:12533684 RGD:2291947 NCBI chrNW_004936588:579,816...601,033 JBrowse link
cervical squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase RNA specific disease_progression ISO protein:increased expression:cervix squamous epithelium (human) RGD PMID:28109322 RGD:125097518 NCBI chrNW_004936580:4,183,016...4,208,341 JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO protein:increased expression:uterine cervix RGD PMID:17694953 RGD:1643352 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Birc2 baculoviral IAP repeat containing 2 disease_progression ISO DNA, protein:amplification, increased expression:uterine cervix, nucleus RGD PMID:12208731 RGD:1643529 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Brip1 BRCA1 interacting helicase 1 severity ISO mRNA, protein:increased expression:uterine cervix, nucleus (human) RGD PMID:24708616 RGD:11252104 NCBI chrNW_004936490:3,001,445...3,139,538 JBrowse link
G Ccl22 C-C motif chemokine ligand 22 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936475:9,432,505...9,436,240 JBrowse link
G Ccr4 C-C motif chemokine receptor 4 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936473:23,321,167...23,323,075 JBrowse link
G Cd82 CD82 molecule ISO protein:decreased expression:uterine cervix RGD PMID:15642213 RGD:2289399
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:uterine cervix RGD PMID:18565574 RGD:2299119 NCBI chrNW_004936504:4,898,947...4,927,195 JBrowse link
G Fgf7 fibroblast growth factor 7 ISO cervical squamous cell carcinoma; mRNA:increased expression:cervical squamous cells RGD PMID:17306351 RGD:2289084 NCBI chrNW_004936471:11,636,733...11,692,782 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 no_association ISO DNA:missense mutation:cds: p.S249G (human) RGD PMID:11605053 RGD:38500202 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit disease_progression ISO protein:increased expression:uterine cervix RGD PMID:15514944 RGD:2293757 NCBI chrNW_004936488:4,384,710...4,388,118 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit ISO protein:decreased expression:uterine cervix RGD PMID:15514944 RGD:2293757 NCBI chrNW_004936599:3,642,504...3,649,294 JBrowse link
G Foxp3 forkhead box P3 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G LOC101977033 thymidine phosphorylase disease_progression ISO RGD PMID:16803522 RGD:2293719 NCBI chrNW_004936629:315,609...320,356 JBrowse link
G Pdpn podoplanin disease_progression ISO RGD PMID:16528371 RGD:2292237 NCBI chrNW_004936474:1,751,159...1,779,011 JBrowse link
G Smad3 SMAD family member 3 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO protein:decreased expression:uterine cervix RGD PMID:16619570 RGD:2290402 NCBI chrNW_004936594:3,232,433...3,244,241 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 disease_progression ISO mRNA:increased expression:uterine cervix RGD PMID:15337562 RGD:2291959 NCBI chrNW_004936512:7,427,926...7,448,700 JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936737:1,901,749...1,904,382 JBrowse link
G Tnfsf4 TNF superfamily member 4 severity ISO RGD PMID:28086903 RGD:38455996 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
G Tp53 tumor protein p53 disease_progression ISO RGD PMID:17969407 RGD:2298526 NCBI chrNW_004936595:919,807...935,367 JBrowse link
cervix carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO DNA:SNPs (human) RGD PMID:19202550 RGD:2315691 NCBI chrNW_004936877:666,545...669,351 JBrowse link
G Bag1 BAG cochaperone 1 ISO protein:increased expression:uterine cervix RGD PMID:10047462 RGD:2293889 NCBI chrNW_004936524:1,793,001...1,804,145 JBrowse link
G Bak1 BCL2 antagonist/killer 1 ISO DNA:missense mutations:exon:multiple (human) RGD PMID:12771926 RGD:2315701 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Ccnd3 cyclin D3 ISO RGD PMID:14751136 RGD:2316013 NCBI chrNW_004936476:17,799,754...17,886,835 JBrowse link
G Cd9 CD9 molecule disease_progression ISO RGD PMID:14695144 RGD:2326206 NCBI chrNW_004936709:1,497,504...1,530,114 JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 exacerbates ISO mRNA, protein:increased expression:cervix epithelium (human) RGD PMID:24737201 RGD:42722607 NCBI chrNW_004936599:3,663,288...3,670,048 JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 ISO DNA:SNPs (human) RGD PMID:19202550 RGD:2315691 NCBI chrNW_004936523:6,661,119...6,686,988 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO DNA:missense mutation:CDS:amino acid S249C, only found in 1/51 primary tumors and no cell lines tested implying that mutation frequency is much lower than previously reported
DNA:missense mutations:CDS:somatic mutations found in 3/12 (25%) of cervix carcinomas, all mutations are equivalent to activating germline mutations which cause thanatophoric dysplasia
RGD PMID:10471491 PMID:11114733 RGD:2289864 RGD:2289865 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:polymorphisms:cds:p.I143V, p.K178R (human) RGD PMID:17234722 RGD:2317690 NCBI chrNW_004936486:16,744,607...16,923,209 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 disease_progression ISO RGD PMID:16803521 RGD:2300207 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO protein:increased tyrosine phosphorylation:cervix RGD PMID:14675348 RGD:2292568 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO DNA:hypermethylation RGD PMID:16434596 RGD:2300022 NCBI chrNW_004936515:11,026,156...11,046,812 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:SNP: :(rs4148876)(human) RGD PMID:17366619 RGD:6482264 NCBI chrNW_004936476:25,913,699...25,923,419 JBrowse link
G Tk1 thymidine kinase 1 ISO protein:increased expression:serum (human) RGD PMID:11474248 RGD:2317243 NCBI chrNW_004936594:2,784,891...2,794,693 JBrowse link
G Tsg101 tumor susceptibility 101 ISO mRNA:alternative form:uterine cervix
mRNA:alternative forms:uterine cervix:multiple
RGD PMID:10505033 PMID:10600297 RGD:2291851 RGD:2291852 NCBI chrNW_004936590:61,352...62,037 JBrowse link
cervix uteri carcinoma in situ term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 ISO protein:increased expression:uterine cervix RGD PMID:19473694 RGD:2325246 NCBI chrNW_004936710:2,301,470...2,388,533 JBrowse link
G Bcl2 BCL2 apoptosis regulator disease_progression ISO protein:increased expression:uterine cervix RGD PMID:18561741 RGD:2298889 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Brca1 BRCA1 DNA repair associated ISO DNA:deletions:exon RGD PMID:10442317 RGD:2298942 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Cadm1 cell adhesion molecule 1 severity ISO RGD PMID:17009984 RGD:2289089 NCBI chrNW_004936542:569,739...883,738 JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:uterine cervix RGD PMID:18301453 RGD:2293574
G Ccne1 cyclin E1 ISO protein:increased expression:uterine cervix RGD PMID:18301453 RGD:2293574 NCBI chrNW_004936570:5,536,817...5,547,880 JBrowse link
G Ccng1 cyclin G1 ISO protein:increased expression:uterine cervix RGD PMID:16845792 RGD:2316022 NCBI chrNW_004936515:614,287...621,213 JBrowse link
G Cd274 CD274 molecule severity ISO associated with Papillomavirus Infections; protein:increased expression:dendritic cell RGD PMID:23521696 RGD:40822817 NCBI chrNW_004936539:132,870...145,288 JBrowse link
G Cd46 CD46 molecule ISO protein:increased expression:uterine cervix RGD PMID:9358772 RGD:2293549 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G Cdh1 cadherin 1 ISO DNA:hypermethylation:uterine cervix RGD PMID:17894941 RGD:2289490 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdk4 cyclin dependent kinase 4 disease_progression ISO associated with Papillomavirus Infections;protein:increased expression:cervix epithelium RGD PMID:18301453 RGD:2293574 NCBI chrNW_004936646:1,886,262...1,889,260 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO protein:increased expression:epithelial cell: RGD PMID:9546362 RGD:8662446 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B disease_progression ISO associated with Papillomavirus Infections;protein:decreased expression:cervical epithelium RGD PMID:18301453 RGD:2293574 NCBI chrNW_004936587:4,573,166...4,578,480 JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO protein:increased expression:uterine cervix RGD PMID:17632454 RGD:2289695 NCBI chrNW_004936652:3,576,975...3,582,790 JBrowse link
G Csf1r colony stimulating factor 1 receptor disease_progression ISO protein:increased expression:uterine cervix RGD PMID:18565574 RGD:2299119 NCBI chrNW_004936504:4,898,947...4,927,195 JBrowse link
G Ctnna1 catenin alpha 1 disease_progression ISO protein:decreased expression:uterine cervix RGD PMID:11161853 RGD:2289797 NCBI chrNW_004936531:7,865,907...8,036,020 JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 ISO protein:decreased expression:cervical lesions:targetted by the HPV oncoprotein E6 for ubiquitin-mediated proteolysis RGD PMID:15221964 RGD:2306812 NCBI chrNW_004936833:551,989...843,064 JBrowse link
G Faslg Fas ligand ISO associated with Papillomavirus Infections RGD PMID:17433060 RGD:2290052 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Hdac1 histone deacetylase 1 ISO protein:increased expression:uterine cervix RGD PMID:19147762 RGD:2306200 NCBI chrNW_004936474:15,320,635...15,351,418 JBrowse link
G Hdac2 histone deacetylase 2 ISO protein:increased expression:uterine cervix RGD PMID:19147762 RGD:2306200 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Hdac6 histone deacetylase 6 ISO protein:increased expression:uterine cervix RGD PMID:19147762 RGD:2306200 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO protein:decreased expression:serum:significantly decreased (p<0.0001), levels inversely associated with serum IGF-II levels (p<0.01)
mRNA:decreased expression:tumor:significant decrease in cancer relative to controls (P=0.03)
RGD PMID:14675666 PMID:17709267 RGD:2290004 RGD:2290021 NCBI chrNW_004936478:20,511,490...20,518,251 JBrowse link
G Il1b interleukin 1 beta susceptibility ISO associated with Papillomavirus Infections;DNA:SNP:promoter: -511 C>T (rs16944)(human) RGD PMID:25893807 RGD:36174015 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G LOC101974254 X-linked inhibitor of apoptosis ISO protein:increased expression:uterine cervix RGD PMID:18325467 RGD:2315850 NCBI chrNW_004936479:6,677,533...6,724,800 JBrowse link
G LOC101976563 matrix Gla protein ISO RGD PMID:17960611 RGD:2293584 NCBI chrNW_004936587:2,601,419...2,605,848 JBrowse link
G Mlh1 mutL homolog 1 ISO protein:increased expression:uterine cervix RGD PMID:15807307 RGD:2293515 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO protein:increased expression:uterine cervix RGD PMID:16619570 RGD:2290402 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Msh2 mutS homolog 2 ISO protein:increased expression:uterine cervix RGD PMID:15807307 RGD:2293515 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17303386 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Pdcd1 programmed cell death 1 severity ISO associated with Papillomavirus Infections; protein:increased expression:T cell RGD PMID:23521696 RGD:40822817 NCBI chrNW_004936745:152,571...163,712 JBrowse link
G Phb prohibitin ISO protein:increased expression:uterine cervix RGD PMID:16426920 RGD:2292398 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
G Pou4f1 POU class 4 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20190800 NCBI chrNW_004936511:2,857,017...2,859,705 JBrowse link
G Pten phosphatase and tensin homolog ISO protein:decreased expression:uterine cervix RGD PMID:17672936 RGD:2298701 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression ISO protein:increased expression:uterine cervix, epithelial cell RGD PMID:18565574 RGD:2299119 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO associated with Adenocarcinoma RGD PMID:18234283 RGD:2299896 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit disease_progression ISO protein:altered localization, increased expression:nucleus, uterine cervix RGD PMID:16850495 RGD:2298759 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Skp2 S-phase kinase associated protein 2 severity ISO associated with Papillomavirus Infections RGD PMID:19094580 RGD:2315036 NCBI chrNW_004936518:5,635,856...5,664,057 JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 disease_progression ISO associated with Papillomavirus Infections;protein:altered expression:uterine cervix (human) RGD PMID:19718710 RGD:11039410 NCBI chrNW_004936490:5,055,258...5,059,118 JBrowse link
G Stat3 signal transducer and activator of transcription 3 disease_progression ISO protein:increased expression:nucleus
protein:increased serine phosphorylation:cervix epithelium
RGD PMID:16005944 PMID:17110342 RGD:2291916 RGD:2298536 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO protein:increased expression:uterine cervix RGD PMID:17644806 RGD:2291985 NCBI chrNW_004936815:468,987...492,666 JBrowse link
G Thrb thyroid hormone receptor beta ISO DNA:loss of heterozygosity (human) RGD PMID:11483913 RGD:2315099 NCBI chrNW_004936473:15,766,214...15,986,389 JBrowse link
G Top2a DNA topoisomerase II alpha ISO RGD PMID:19051821 RGD:2315126 NCBI chrNW_004936490:15,441,463...15,465,692 JBrowse link
G Tp63 tumor protein p63 disease_progression ISO RGD PMID:16804722 RGD:2315435 NCBI chrNW_004936578:492,267...705,282 JBrowse link
G Tp73 tumor protein p73 disease_progression ISO mRNA:increased expression:uterine cervix RGD PMID:11870517 RGD:2290589 NCBI chrNW_004936737:171,894...211,464 JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:uterine cervix RGD PMID:19723043 RGD:2315456 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
chorioamnionitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO RGD PMID:22578261 RGD:6767308 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:villous trophoblast RGD PMID:12700199 RGD:12904022 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21493953 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il6 interleukin 6 ISO associated with Premature Birth;protein:increased expression:tracheal aspirate fluid:
protein:increased expression: cervicovaginal fluid :
protein:increased expression:plasma
RGD PMID:15547537 PMID:25011638 PMID:25687566 RGD:12791291 RGD:12792243 RGD:5128667 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Lta lymphotoxin alpha severity ISO associated with Premature Birth;DNA:SNP:promoter:250G>A (human) RGD PMID:15128916 RGD:12904055 NCBI chrNW_004936727:1,940,081...1,941,022 JBrowse link
G Mmp9 matrix metallopeptidase 9 severity ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:12712078 RGD:13204828 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Tgfb1 transforming growth factor beta 1 severity ISO protein:increased expression:amniotic fluid RGD PMID:19332995 RGD:4145137 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tnf tumor necrosis factor no_association
severity
ISO associated with Premature Birth;DNA:SNP:promoter:c.-308 G>A (human)
associated with Premature Birth;DNA:SNP:promoter:c.-238G>A (human)
RGD PMID:15128916 RGD:12904055 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ISO associated with Premature Obstetric Labor;protein:increased expression:amniotic fluid: RGD PMID:19591072 RGD:127229904 NCBI chrNW_004936476:18,577,825...18,583,675 JBrowse link
choriocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf8 fibroblast growth factor 8 ISO protein:increased expression:testicular germ cell neoplasms RGD PMID:11764380 RGD:2289339 NCBI chrNW_004936600:4,004,847...4,010,626 JBrowse link
G Igf2 insulin like growth factor 2 disease_progression ISO protein:increased expression:tumor:elevated IGF-II increased choriocarcinoma cell invasion via activation of INSR RGD PMID:17556377 RGD:2290454 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Insr insulin receptor disease_progression ISO protein:increased activity:tumor:IGF-II increased choriocarcinoma cell invasion via activation of INSR RGD PMID:17556377 RGD:2290454 NCBI chrNW_004936588:4,345,306...4,453,380 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO mRNA:increased expression:mononuclear cytotrophoblast cell RGD PMID:8504434 RGD:2292200 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO mRNA:increased expression:mononuclear cytotrophoblast cell RGD PMID:8504434 RGD:2292200 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO DNA, protein:hypermethylation, decreased expression:promoter, placenta RGD PMID:15507671 RGD:2290418 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
endometrial adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 ISO protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chrNW_004936470:37,105,469...37,328,183 JBrowse link
G Angpt2 angiopoietin 2 ISO protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chrNW_004936615:4,472,261...4,524,537 JBrowse link
G Arid1a AT-rich interaction domain 1A treatment ISO human cell in mouse model RGD PMID:21900401 RGD:126725086 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Axin2 axin 2 ISO RGD PMID:11940574 RGD:13432156 NCBI chrNW_004936541:7,155,963...7,242,466 JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein like disease_progression ISO RGD PMID:28654152 RGD:14394612 NCBI chrNW_004936888:42,646...56,589 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) ISO RGD PMID:11506079 RGD:2326173 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 ISO protein:increased expression:endometrium RGD PMID:16112719 RGD:2289850 NCBI chrNW_004936470:35,449,920...35,473,635 JBrowse link
G Foxo3 forkhead box O3 severity ISO associated with Obesity;protein:decreased expression:endometrium (human) RGD PMID:26045339 RGD:11530998 NCBI chrNW_004936564:4,788,036...4,907,600 JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:endometrium (rat) RGD PMID:19426485 RGD:2312621 NCBI chrNW_004936647:3,904,787...3,914,223 JBrowse link
G Irf1 interferon regulatory factor 1 ISO DNA:deletions (rat) RGD PMID:19075038 RGD:5128782 NCBI chrNW_004936647:2,686,247...2,693,633 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit no_association ISO protein, mRNA::endometrial epithelium and stroma:no correlation between expression and type of tissue or cancer stage or grade RGD PMID:10684716 RGD:2290482 NCBI chrNW_004936522:3,034,364...3,037,632 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12D, p.G12S, p.Q61H (rat) RGD PMID:10775052 RGD:1600499 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO protein:decreased phosphorylation:endometrium (human)
human tumor in a mouse model
RGD PMID:14760076 PMID:23402905 RGD:13703125 RGD:13703137 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO human tumor in a mouse model
protein:decreased phosphorylation:endometrium (human)
RGD PMID:14760076 PMID:23402905 RGD:13703125 RGD:13703137 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO DNA:mutations:multiple (human) RGD PMID:21478295 RGD:13441595 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Ptges prostaglandin E synthase ISO protein:increased expression:endometrium RGD PMID:11592775 RGD:2300089 NCBI chrNW_004936487:16,959,263...16,968,909 JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO DNA:amplification (rat) RGD PMID:15942940 RGD:2324953 NCBI chrNW_004936532:6,348,041...6,390,144 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO mRNA:decreased expression:endometrium RGD PMID:15745937 RGD:1579943 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
G Tp53 tumor protein p53 disease_progression ISO DNA:missense mutations
protein:increased expression:endometrium
RGD PMID:1540970 RGD:2290541 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Tsg101 tumor susceptibility 101 ISO mRNA:alternative forms RGD PMID:10027311 RGD:2291854 NCBI chrNW_004936590:61,352...62,037 JBrowse link
endometrial cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb3 adrenoceptor beta 3 susceptibility ISO associated with Obesity;DNA:polymorphism: :p.W64R (human) RGD PMID:15743038 RGD:2313164 NCBI chrNW_004936710:1,410,589...1,413,279 JBrowse link
G Akt2 AKT serine/threonine kinase 2 severity ISO DNA:snp:intron:c.287+993G>A (rs892119) (human) RGD PMID:22146979 RGD:13432140 NCBI chrNW_004936661:2,652,568...2,694,039 JBrowse link
G Ang angiogenin ISO protein:increased expression:serum RGD PMID:9119882 RGD:2317659 NCBI chrNW_004936880:39,372...40,070 JBrowse link
G Apc APC regulator of WNT signaling pathway severity
treatment
ISO DNA:mutations, haplotype:cds:multiple (human)
with Pten knockout
human cells in a mouse model
protein:increased expression:endometrium (human)
RGD PMID:15951972 PMID:22907428 PMID:23288720 PMID:29876005 RGD:13524585 RGD:13524624 RGD:13673916 RGD:13673917 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO DNA:nonsense mutation, missense mutations: :p.W188X, p.P112L, p.R237C (human) RGD PMID:11465542 RGD:2315878 NCBI chrNW_004936877:666,545...669,351 JBrowse link
G Ar androgen receptor ISO RGD PMID:15721279 RGD:1578689 NCBI chrNW_004936635:485,903...647,820 JBrowse link
G Arid1a AT-rich interaction domain 1A onset ISO protein:decreased expression:endometrium (human) RGD PMID:23887303 RGD:126779522 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO RGD PMID:17164260 RGD:2293868 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Bad BCL2 associated agonist of cell death disease progression ISO protein:altered expression:endometrium (human) RGD PMID:24645842 RGD:13432164 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bag1 BAG cochaperone 1 ISO protein:increased expression:endometrium RGD PMID:15297164 RGD:2293886 NCBI chrNW_004936524:1,793,001...1,804,145 JBrowse link
G Bcl2l1 BCL2 like 1 ISO protein:increased expression:endometrium RGD PMID:17311011 RGD:1643476 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Brca2 BRCA2 DNA repair associated ISO DNA:deletion, frameshift mutation RGD PMID:10451700 RGD:2296027 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Bst2 bone marrow stromal cell antigen 2 treatment ISO protein:increased expression:endometrium: RGD PMID:22729361 PMID:26498112 RGD:14398492 RGD:14398498
G Cd59 CD59 molecule (CD59 blood group) ISO protein:increased expression:endometrium RGD PMID:10637067 RGD:2293548 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G Cd9 CD9 molecule ISO RGD PMID:11505398 RGD:2326208 NCBI chrNW_004936709:1,497,504...1,530,114 JBrowse link
G Cdc25b cell division cycle 25B ISO RGD PMID:14559803 RGD:4105451 NCBI chrNW_004936485:14,897,050...14,914,034 JBrowse link
G Cdc25c cell division cycle 25C ISO DNA:mutation (human) RGD PMID:12124347 RGD:4105455 NCBI chrNW_004936531:7,471,722...7,499,781 JBrowse link
G Cdh1 cadherin 1 ISO OMIM NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO DNA:deletion (rat) RGD PMID:18558284 RGD:2316081 NCBI chrNW_004936652:3,576,975...3,582,790 JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:17023034 RGD:4892642 NCBI chrNW_004936567:1,411,080...1,418,332 JBrowse link
G Comt catechol-O-methyltransferase no_association
susceptibility
ISO DNA:hypermethylation:promoter
DNA:polymorphism: :p.V158M
RGD PMID:12810635 PMID:15285606 PMID:17442187 RGD:2289714 RGD:2289721 RGD:2289723 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 exacerbates
ameliorates
ISO protein:decreased expression:endometrium (human)
human EFEMP2 knockdown cell line in a mouse model
RGD PMID:28177909 RGD:42722012 NCBI chrNW_004936599:3,663,288...3,670,048 JBrowse link
G Egf epidermal growth factor severity ISO DNA:snps:5'utr:multiple (human) RGD PMID:19319135 RGD:13673915 NCBI chrNW_004936563:1,058,803...1,181,393 JBrowse link
G Fgf1 fibroblast growth factor 1 disease_progression ISO mRNA:increased expression:myometrium RGD PMID:8685603 RGD:2298516 NCBI chrNW_004936504:11,590,687...11,684,410 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Endometrial cancer, somatic ClinVar PMID:7719344 PMID:8651276 PMID:9462761 PMID:9719378 PMID:10851026 PMID:11121055 PMID:11390973 PMID:12124745 PMID:14499350 PMID:15975938 PMID:16440883 PMID:17525745 PMID:18552176 PMID:20301628 PMID:21367659 PMID:22238366 PMID:22664175 PMID:23002168 PMID:23495007 PMID:23546041 PMID:24489893 PMID:25157968 PMID:25741868 PMID:25867380 PMID:26380986 PMID:26619011 PMID:28492532 PMID:31145570 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Ghrh growth hormone releasing hormone ISO mRNA:increased expression:tumor:expression in 17/22 specimens RGD PMID:10022420 PMID:15784701 RGD:2289974 RGD:2301423 NCBI chrNW_004936561:3,946,256...3,954,472 JBrowse link
G Hoxb13 homeobox B13 ISO RGD PMID:15756448 RGD:2314730 NCBI chrNW_004936490:12,688,572...12,690,908 JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:decreased expression:endometrium (human) RGD PMID:19424634 RGD:5688747 NCBI chrNW_004936556:741,718...746,016 JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:serum RGD PMID:9119882 RGD:2317659 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Endometrial cancer ClinVar PMID:6320174 PMID:11745231 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 PMID:17384584 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19114683 PMID:19255327 PMID:19679400 PMID:19773371 PMID:20921462 PMID:20921465 PMID:21228335 PMID:21975775 PMID:23014527 PMID:23182985 PMID:23406027 PMID:25044103 PMID:25157968 PMID:31666701 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G LOC101954950 aromatase ISO DNA:SNP::increase in frequency of mutant heterozygote C/T (p=0.0004) RGD PMID:18497059 RGD:2301045 NCBI chrNW_004936471:13,107,603...13,136,910 JBrowse link
G LOC101960169 junction plakoglobin ISO protein:decreased expression:endometrium RGD PMID:12635138 RGD:2301747 NCBI chrNW_004936490:16,671,176...16,694,552 JBrowse link
G LOC101966155 alpha fetoprotein severity ISO protein:increased expression:serum RGD PMID:17659325 RGD:2292039 NCBI chrNW_004936598:2,058,474...2,077,711 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO DNA:SNP:CDS:rs4646903 T/T genotype, rs4646903-rs1048943 T-A haplotype, rs4646903 (TT) combined with SULT1A1 SNP rs9282861 (GA + AA) or rs4646903 (TT) combined with SULT1E1 SNP rs3736599 (GA+AA) RGD PMID:18318428 RGD:2301040 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO DNA:SNP::differences in allele and genotype distribution for CYP1A2*1F polymorphism (p=0.00000002) RGD PMID:18497059 RGD:2301045 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G LOC101977033 thymidine phosphorylase ISO RGD PMID:18348659 RGD:2293715 NCBI chrNW_004936629:315,609...320,356 JBrowse link
G Lta lymphotoxin alpha susceptibility ISO DNA:polymorphism: :252A>G, 804C>A (human) RGD PMID:17045328 RGD:2313259 NCBI chrNW_004936727:1,940,081...1,941,022 JBrowse link
G Mcph1 microcephalin 1 ISO DNA:deletions:exons:multiple (human) RGD PMID:20638839 RGD:9589018 NCBI chrNW_004936615:4,386,667...4,580,720 JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Endometrial cancer, somatic ClinVar PMID:8566964 PMID:8574961 PMID:8592341 PMID:9697702 PMID:9806477 PMID:10480359 PMID:10732761 PMID:11112663 PMID:11385712 PMID:11429708 PMID:11601928 PMID:11781295 PMID:11948175 PMID:12112654 PMID:12362047 PMID:12373605 PMID:12522551 PMID:12618391 PMID:12810663 PMID:12919140 PMID:15300854 PMID:15713769 PMID:16395668 PMID:16451135 PMID:16830052 PMID:17135187 PMID:17192056 PMID:17510385 PMID:18373977 PMID:18383312 PMID:18470917 PMID:18547406 PMID:18561205 PMID:18566915 PMID:18726168 PMID:18772310 PMID:19224586 PMID:19267393 PMID:19698169 PMID:19863800 PMID:20233461 PMID:22322191 PMID:22949387 PMID:23403630 PMID:24033266 PMID:24362816 PMID:25741868 PMID:26467025 PMID:26845104 PMID:28135145 PMID:28449805 PMID:28492532 PMID:28874130 PMID:30521064 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Mlh3 mutL homolog 3 ISO OMIM NCBI chrNW_004936488:4,164,322...4,195,408 JBrowse link
G Mmp7 matrix metallopeptidase 7 disease_progression ISO protein:increased expression:endometrium RGD PMID:17352221 RGD:2298522 NCBI chrNW_004936551:5,388,456...5,395,071 JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO DNA:deletions:intron:IVS4_delT (human) RGD PMID:15048091 RGD:2317737 NCBI chrNW_004936674:466,495...528,072 JBrowse link
G Msh3 mutS homolog 3 ISO OMIM NCBI chrNW_004936469:82,967...275,772 JBrowse link
G Msh6 mutS homolog 6 ISO OMIM NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: malignant endometrial neoplasm ClinVar PMID:11818965 PMID:12606733 PMID:15931596 PMID:15987719 PMID:16492921 PMID:16557584 PMID:17489848 PMID:17956577 PMID:18534194 PMID:19032956 PMID:19245865 PMID:19394335 PMID:19732775 PMID:19793053 PMID:19836313 PMID:19953527 PMID:19998059 PMID:20418187 PMID:20848659 PMID:21063410 PMID:21171015 PMID:21178863 PMID:21815886 PMID:21952991 PMID:22158503 PMID:22297469 PMID:22473953 PMID:22703879 PMID:22744763 PMID:22926731 PMID:23035301 PMID:23108399 PMID:23361220 PMID:23561487 PMID:23625202 PMID:23805267 PMID:24033266 PMID:24082139 PMID:24278394 PMID:24444654 PMID:24728327 PMID:24953332 PMID:25741868 PMID:25820570 PMID:26467025 PMID:26822237 PMID:26845104 PMID:27829682 PMID:28492532 PMID:28634180 NCBI chrNW_004936474:26,484,316...26,492,652 JBrowse link
G Notch1 notch receptor 1 ISO mRNA:increased expression:endometrium RGD PMID:11078798 RGD:2299153 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Notch4 notch receptor 4 ISO mRNA:decreased expression:endometrium RGD PMID:11078798 RGD:2299153 NCBI chrNW_004936727:1,386,842...1,409,823 JBrowse link
G Pgm1 phosphoglucomutase 1 ISO RGD PMID:508567 RGD:2299870 NCBI chrNW_004936692:1,160,836...1,221,270 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta onset ISO mRNA:increased expression:endometrium (human) RGD PMID:28002804 RGD:13674181 NCBI chrNW_004936540:907,118...1,041,814 JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO RGD PMID:21478295 RGD:13441595 NCBI chrNW_004936623:3,672,201...3,696,959 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO DNA:mutations:multiple (human) RGD PMID:21984976 RGD:13674179 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Endometrial cancer, somatic ClinVar PMID:10480359 PMID:15256438 PMID:16472587 PMID:22703879 PMID:24033266 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Endometrial cancer
ClinVar Annotator: match by term: Endometrial cancer, somatic
ClinVar PMID:9536098 PMID:10866302 PMID:10920277 PMID:11504908 PMID:16014636 PMID:17576681 PMID:18767981 PMID:20085938 PMID:21103832 PMID:21824802 PMID:21828076 PMID:25157968 PMID:26619011 PMID:26795104 PMID:27535533 PMID:28492532 PMID:28677221 PMID:29706350 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Shbg sex hormone binding globulin ISO DNA:polymorphism:exon:p.D327N (human) RGD PMID:17315164 RGD:1625245 NCBI chrNW_004936595:894,048...897,249 JBrowse link
G Smad2 SMAD family member 2 ISO protein:increased expression:endometrium RGD PMID:12883738 RGD:2299970 NCBI chrNW_004936497:14,723,199...14,812,160 JBrowse link
G Smad3 SMAD family member 3 ISO protein:increased expression:endometrium RGD PMID:12883738 RGD:2299970 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Smad7 SMAD family member 7 disease_progression ISO mRNA:increased expression:endometrium RGD PMID:15661223 RGD:2299963 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO DNA:hypermethylated RGD PMID:15159323 RGD:2298926 NCBI chrNW_004936507:10,013,982...10,015,480 JBrowse link
G Spag9 sperm associated antigen 9 ISO protein:increased expression:serum: RGD PMID:24460345 RGD:30296659 NCBI chrNW_004936490:10,663,155...10,796,658 JBrowse link
G Stk11 serine/threonine kinase 11 ISO RGD PMID:18245476 RGD:2291944 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO mRNA:decreased expression:endometrium RGD PMID:15273280 RGD:2290435 NCBI chrNW_004936602:1,488,993...1,496,108 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:serum (human) RGD PMID:8920779 RGD:5131439 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:serum (human) RGD PMID:8920779 RGD:5131439 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Wt1 WT1 transcription factor disease_progression ISO RGD PMID:19443388 RGD:2315542 NCBI chrNW_004936533:5,411,949...5,459,693 JBrowse link
endometrial carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,735,206...1,778,100 JBrowse link
G Apc APC regulator of WNT signaling pathway onset ISO ClinVar Annotator: match by term: Endometrial carcinoma
DNA:hypermethylation:promoter: (human)
RGD
ClinVar
PMID:19900189 PMID:21363919 PMID:25741868 PMID:28492532 RGD:13524625 RGD:13525011 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12702580 PMID:17656264 PMID:22290698 PMID:28492532 NCBI chrNW_004936488:3,835,021...3,882,055 JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12810666 PMID:19781682 PMID:21787400 PMID:23555315 PMID:24728327 PMID:25186627 PMID:25741868 PMID:27443514 PMID:28492532 PMID:30651582 PMID:31159747 PMID:31206626 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Aurka aurora kinase A ISO mRNA, protein:increased expression:endometrium RGD PMID:16311121 RGD:2293878 NCBI chrNW_004936875:295,238...310,457 JBrowse link
G Aurkb aurora kinase B disease_progression ISO mRNA, protein:increased expression:endometrium RGD PMID:16311121 RGD:2293878 NCBI chrNW_004936595:1,435,601...1,437,423 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutations, nonsense mutation:cds:multiple (human)
ClinVar Annotator: match by term: Endometrial carcinoma
RGD
ClinVar
PMID:16144912 PMID:28492532 RGD:13432166 NCBI chrNW_004936592:4,728,371...4,833,830 JBrowse link
G Brca1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7581445 PMID:10667592 PMID:10667595 PMID:12566964 PMID:12955716 PMID:16014699 PMID:16168118 PMID:16267036 PMID:16284991 PMID:16685647 PMID:17924331 PMID:18489799 PMID:18936166 PMID:19147582 PMID:19340607 PMID:20104584 PMID:21520273 PMID:21702907 PMID:21990134 PMID:23161852 PMID:23867111 PMID:25452441 PMID:25637381 PMID:25741868 PMID:25777348 PMID:26467025 PMID:26681312 PMID:28324225 PMID:28492532 PMID:32295079 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brca2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:20104584 PMID:22476429 PMID:22703879 PMID:24448499 PMID:24916970 PMID:25036526 PMID:25348012 PMID:25741868 PMID:26467025 PMID:26689913 PMID:27495310 PMID:27974047 PMID:28492532 PMID:29470806 PMID:30555256 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Bricd5 BRICHOS domain containing 5 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,836,566...1,838,950 JBrowse link
G Bsg basigin (Ok blood group) disease_progression ISO protein:increased expression:endometrium RGD PMID:17342307 RGD:2296029 NCBI chrNW_004936588:181,688...189,795 JBrowse link
G Caskin1 CASK interacting protein 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,856,529...1,868,107 JBrowse link
G Ccnb1 cyclin B1 ISO RGD PMID:17483252 RGD:2289230 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Cd82 CD82 molecule disease_progression ISO RGD PMID:12684410 RGD:2289403
G Cdh1 cadherin 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:8075649 PMID:11598162 PMID:12588804 PMID:14500541 PMID:20233471 PMID:20921021 PMID:22470475 PMID:22703879 PMID:24728327 PMID:25067988 PMID:25637381 PMID:25741868 PMID:25980754 PMID:26182300 PMID:26467025 PMID:27616075 PMID:27720647 PMID:28125075 PMID:28135145 PMID:28352678 PMID:28492532 PMID:30311375 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdh13 cadherin 13 disease_progression ISO DNA:hypomethylation RGD PMID:18519763 RGD:2298985 NCBI chrNW_004936641:3,925,185...4,223,421 JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25186627 PMID:25741868 PMID:26094658 PMID:26467025 PMID:28492532 PMID:28779002 PMID:30303537 PMID:30374176 PMID:30851065 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G CUNH11orf65 chromosome unknown C11orf65 homolog ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12810666 PMID:19781682 PMID:21787400 PMID:23555315 PMID:25741868 PMID:28492532 PMID:30651582 PMID:31159747 NCBI chrNW_004936551:305,617...343,369 JBrowse link
G Dhfr dihydrofolate reductase ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936469:67,962...83,116 JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,808,184...1,810,735 JBrowse link
G E4f1 E4F transcription factor 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,811,131...1,829,193 JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,794,673...1,807,306 JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 disease_progression ISO RGD PMID:15741767 RGD:2315693 NCBI chrNW_004936523:6,661,119...6,686,988 JBrowse link
G Fgf7 fibroblast growth factor 7 ISO mRNA:decreased expression:endometrium RGD PMID:9070494 RGD:2301091 NCBI chrNW_004936471:11,636,733...11,692,782 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7719344 PMID:8651276 PMID:8696350 PMID:9462761 PMID:9719378 PMID:10851026 PMID:11121055 PMID:11390973 PMID:12000365 PMID:12124745 PMID:12145519 PMID:12900900 PMID:14499350 PMID:15975938 PMID:16440883 PMID:16531735 PMID:17525745 PMID:18552176 PMID:20301628 PMID:20856019 PMID:21367659 PMID:21397175 PMID:22238366 PMID:22664175 PMID:23002168 PMID:23495007 PMID:23546041 PMID:24489893 PMID:25157968 PMID:25706251 PMID:25741868 PMID:25867380 PMID:25937001 PMID:26380986 PMID:26619011 PMID:27079505 PMID:28492532 PMID:31145570 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Grb2 growth factor receptor bound protein 2 severity ISO Shc-Grb2 complex;protein:increased expression:serum (human) RGD PMID:22459351 RGD:13441552 NCBI chrNW_004936594:592,760...661,369 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta severity ISO protein:increased expression:endometrium (human) RGD PMID:27050373 RGD:13524565 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Hdac3 histone deacetylase 3 disease_progression ISO RGD PMID:18714364 RGD:2306205 NCBI chrNW_004936504:12,530,546...12,546,556 JBrowse link
G Hras HRas proto-oncogene, GTPase disease_progression ISO DNA:snps:cds: (human)
protein:increased expression:endometrial stroma, cytoplasm (human)
RGD PMID:8960147 PMID:9641239 RGD:13441555 RGD:13781876 NCBI chrNW_004936888:375,372...378,125 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit disease_progression ISO protein:increased expression:tumor:positive correlation between expression and tumor grade (P=0.027) RGD PMID:15800680 RGD:2290481 NCBI chrNW_004936522:3,034,364...3,037,632 JBrowse link
G Kiss1 KiSS-1 metastasis suppressor disease_progression ISO mRNA:decreased expression:endometrium RGD PMID:15949424 RGD:2302170 NCBI chrNW_004936567:584,443...595,045 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:6320174 PMID:11745231 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16474405 PMID:16618717 PMID:16987887 PMID:17056636 PMID:17384584 PMID:17704260 PMID:17875937 PMID:18316791 PMID:18794081 PMID:18958496 PMID:19018267 PMID:19020799 PMID:19114683 PMID:19255327 PMID:19679400 PMID:19773371 PMID:20921462 PMID:20921465 PMID:20949621 PMID:21228335 PMID:21686179 PMID:21784453 PMID:21975775 PMID:23014527 PMID:23182985 PMID:23406027 PMID:23885229 PMID:24033266 PMID:24803665 PMID:25044103 PMID:25157968 PMID:25359213 PMID:25741868 PMID:28492532 PMID:29493581 PMID:31666701 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G LOC101963077 phosphoglycolate phosphatase ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,834,016...1,836,359 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 severity ISO protein:increased expression:endometrium (human)
protein:increased phosphorylation:endometrium (human)
RGD PMID:22459351 PMID:29081408 RGD:13441552 RGD:13702082 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 severity ISO protein:increased expression:endometrium (human)
protein:increased phosphorylation:endometrium (human)
RGD PMID:22459351 PMID:29081408 RGD:13441552 RGD:13702082 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:8566964 PMID:8574961 PMID:8592341 PMID:9526167 PMID:9697702 PMID:9806477 PMID:9833759 PMID:10480359 PMID:10732761 PMID:11112663 PMID:11385712 PMID:11429708 PMID:11601928 PMID:11781295 PMID:11948175 PMID:12112654 PMID:12115348 PMID:12362047 PMID:12373605 PMID:12522551 PMID:12618391 PMID:12810663 PMID:12919140 PMID:15133479 PMID:15300854 PMID:15713769 PMID:15849733 PMID:16341804 PMID:16395668 PMID:16451135 PMID:16830052 PMID:16995940 PMID:17135187 PMID:17192056 PMID:17510385 PMID:18373977 PMID:18383312 PMID:18470917 PMID:18547406 PMID:18561205 PMID:18566915 PMID:18726168 PMID:18772310 PMID:19224586 PMID:19267393 PMID:19698169 PMID:19863800 PMID:20233461 PMID:21056691 PMID:21681552 PMID:22322191 PMID:22703879 PMID:22736432 PMID:22949387 PMID:23329266 PMID:23403630 PMID:24033266 PMID:24055113 PMID:24090359 PMID:24362816 PMID:24728327 PMID:24933000 PMID:25637381 PMID:25741868 PMID:26096739 PMID:26332594 PMID:26467025 PMID:26845104 PMID:27600092 PMID:28135145 PMID:28449805 PMID:28492532 PMID:28874130 PMID:30521064 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Mlh3 mutL homolog 3 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12702580 PMID:17656264 PMID:22290698 PMID:25741868 PMID:28492532 NCBI chrNW_004936488:4,164,322...4,195,408 JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,839,135...1,849,307 JBrowse link
G Mmp8 matrix metallopeptidase 8 ISO RGD PMID:10502722 RGD:2306086 NCBI chrNW_004936551:5,228,950...5,238,948 JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Msh2 mutS homolog 2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:1586275 PMID:7585065 PMID:8640829 PMID:9222765 PMID:9718327 PMID:9774676 PMID:12115348 PMID:12362047 PMID:14504054 PMID:15235034 PMID:15655560 PMID:15713769 PMID:15849733 PMID:15862756 PMID:15872200 PMID:16451135 PMID:17192056 PMID:17312306 PMID:17440950 PMID:17531815 PMID:18383312 PMID:18772310 PMID:18822302 PMID:20305446 PMID:21879275 PMID:23047549 PMID:23729658 PMID:24033266 PMID:24278394 PMID:24362816 PMID:25081409 PMID:25479140 PMID:25525159 PMID:25741868 PMID:25964535 PMID:26467025 PMID:26951660 PMID:27449771 PMID:27601186 PMID:28492532 PMID:29212164 PMID:29967336 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Msh3 mutS homolog 3 ISO ClinVar Annotator: match by term: Endometrial carcinoma RGD
ClinVar
PMID:8782829 PMID:25741868 PMID:27476653 PMID:28492532 RGD:1600456 NCBI chrNW_004936469:82,967...275,772 JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:8063241 PMID:9536098 PMID:9774676 PMID:10471527 PMID:10508506 PMID:10521294 PMID:10537275 PMID:10612827 PMID:10938287 PMID:11470537 PMID:11641390 PMID:11709755 PMID:11807791 PMID:11900875 PMID:12019211 PMID:12732731 PMID:14520694 PMID:15098177 PMID:15236168 PMID:15354210 PMID:15483016 PMID:15782118 PMID:15872200 PMID:15952900 PMID:16000562 PMID:16199547 PMID:16203774 PMID:16270383 PMID:16408224 PMID:16464007 PMID:16813607 PMID:16885385 PMID:17453009 PMID:17531815 PMID:17576681 PMID:17594722 PMID:18033691 PMID:18269114 PMID:18301448 PMID:18409202 PMID:18415027 PMID:18566915 PMID:18625694 PMID:18790734 PMID:18809606 PMID:19250818 PMID:19324997 PMID:19389263 PMID:19851887 PMID:19924528 PMID:20028993 PMID:20176959 PMID:20379851 PMID:20487569 PMID:20531397 PMID:20937110 PMID:21081928 PMID:21120944 PMID:21155762 PMID:21836479 PMID:22006311 PMID:22102614 PMID:22290698 PMID:22495361 PMID:22703879 PMID:22851212 PMID:22949379 PMID:23047549 PMID:23263490 PMID:23359684 PMID:23523604 PMID:23554159 PMID:23621914 PMID:23733757 PMID:24033266 PMID:24040339 PMID:24100870 PMID:24323032 PMID:24362816 PMID:24440087 PMID:24728189 PMID:24728327 PMID:24896128 PMID:24933100 PMID:25006859 PMID:25117503 PMID:25203624 PMID:25231023 PMID:25318681 PMID:25479140 PMID:25525159 PMID:25559809 PMID:25637381 PMID:25642631 PMID:25741868 PMID:25801821 PMID:25862369 PMID:25892863 PMID:25980754 PMID:26099011 PMID:26206375 PMID:26333163 PMID:26467025 PMID:26483394 PMID:26517685 PMID:26530882 PMID:26552419 PMID:26681312 PMID:26689913 PMID:26720728 PMID:26805314 PMID:26845104 PMID:26888055 PMID:26898890 PMID:26901136 PMID:26976419 PMID:27064304 PMID:27273229 PMID:27329137 PMID:27487738 PMID:27601186 PMID:27920101 PMID:28125075 PMID:28135145 PMID:28152038 PMID:28176205 PMID:28323777 PMID:28369758 PMID:28466842 PMID:28492532 PMID:28514183 PMID:28528518 PMID:28531214 PMID:28640387 PMID:28765196 PMID:28767289 PMID:28873162 PMID:28912153 PMID:28944238 PMID:29212164 PMID:29360161 PMID:29368341 PMID:29684080 PMID:29887214 PMID:30093976 PMID:30267214 PMID:30612635 PMID:30982232 PMID:31100584 PMID:31391288 PMID:31658756 PMID:31965077 PMID:32615015 PMID:32773772 NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:11818965 PMID:12606733 PMID:16140997 PMID:16338133 PMID:16492921 PMID:16557584 PMID:16616356 PMID:17489848 PMID:17956577 PMID:18414213 PMID:18534194 PMID:19032956 PMID:19245865 PMID:19394335 PMID:19732775 PMID:19793053 PMID:19836313 PMID:19953527 PMID:20725929 PMID:20848659 PMID:21063410 PMID:21171015 PMID:22266422 PMID:22703879 PMID:22926731 PMID:23035301 PMID:23361220 PMID:23605219 PMID:24033266 PMID:24444654 PMID:24728327 PMID:25741868 PMID:25820570 PMID:26467025 PMID:26845104 PMID:27829682 PMID:28492532 NCBI chrNW_004936474:26,484,316...26,492,652 JBrowse link
G Ncoa1 nuclear receptor coactivator 1 ISO mRNA:increased expression:endometrium RGD PMID:14751175 RGD:2298984 NCBI chrNW_004936493:7,368,393...7,605,754 JBrowse link
G Ncor2 nuclear receptor corepressor 2 ISO mRNA:increased expression:endometrium RGD PMID:14751175 RGD:2298984 NCBI chrNW_004936558:658,723...775,263 JBrowse link
G Nos3 nitric oxide synthase 3 disease_progression ISO protein:increased expression:endometrium RGD PMID:9276029 RGD:2292090 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:17200668 PMID:20091115 PMID:21285249 PMID:21365267 PMID:22241545 PMID:22692731 PMID:25186627 PMID:25356972 PMID:25741868 PMID:26283626 PMID:26315354 PMID:26467025 PMID:26689913 PMID:26692951 PMID:26898890 PMID:28440294 PMID:28492532 PMID:28767289 PMID:30287823 PMID:32566746 NCBI chrNW_004936501:8,246,927...8,273,258 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936566:3,924,013...3,951,052 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO DNA:mutations:multiple (human) RGD PMID:23636398 RGD:13628733 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,923,383...1,958,160 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7628019 PMID:7704024 PMID:8072530 PMID:8993976 PMID:9683794 PMID:10479499 PMID:10480359 PMID:12208142 PMID:14756672 PMID:15256438 PMID:15304120 PMID:15521988 PMID:15872200 PMID:16144131 PMID:16472587 PMID:16619239 PMID:17139668 PMID:17557300 PMID:18178629 PMID:18268114 PMID:18273873 PMID:18602922 PMID:18768816 PMID:19132747 PMID:19156169 PMID:19479271 PMID:19526325 PMID:20176959 PMID:20186688 PMID:20186689 PMID:20205264 PMID:20487569 PMID:20531397 PMID:20698049 PMID:21204794 PMID:21239990 PMID:21376568 PMID:22577899 PMID:22703879 PMID:22875147 PMID:22941189 PMID:22949387 PMID:23012243 PMID:23017166 PMID:23435383 PMID:23709753 PMID:23981578 PMID:24027009 PMID:24033266 PMID:24055113 PMID:24130102 PMID:24326041 PMID:24362816 PMID:24434690 PMID:24556621 PMID:24689082 PMID:24728327 PMID:24897087 PMID:25006859 PMID:25117502 PMID:25186627 PMID:25194673 PMID:25345868 PMID:25503501 PMID:25559809 PMID:25567908 PMID:25637381 PMID:25741868 PMID:25856668 PMID:25871621 PMID:25938944 PMID:25980754 PMID:26110232 PMID:26116798 PMID:26272126 PMID:26318770 PMID:26467025 PMID:26483394 PMID:26681312 PMID:26689913 PMID:26811195 PMID:26845104 PMID:26866578 PMID:26898890 PMID:27001570 PMID:27050224 PMID:27203213 PMID:27379089 PMID:27433846 PMID:27435373 PMID:27476653 PMID:27863258 PMID:27878467 PMID:27930734 PMID:28135145 PMID:28492532 PMID:28528518 PMID:28596308 PMID:28873162 PMID:28975465 PMID:29345684 PMID:29785153 PMID:29887214 PMID:30322717 PMID:30608896 PMID:30651582 PMID:30653781 PMID:30680046 PMID:30702970 PMID:31159747 PMID:31300551 PMID:31327751 PMID:31391288 PMID:31433215 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12376507 PMID:17145065 PMID:25529843 PMID:25741868 PMID:26467025 PMID:26748215 PMID:26811195 PMID:28492532 NCBI chrNW_004936889:231,373...250,985 JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:27217144 PMID:28492532 NCBI chrNW_004936660:2,575,255...2,622,867 JBrowse link
G Prkca protein kinase C alpha ISO RGD PMID:11371124 RGD:2292462 NCBI chrNW_004936541:6,231,604...6,488,201 JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7728760 PMID:8980400 PMID:9326929 PMID:9536098 PMID:9740666 PMID:10555148 PMID:10866302 PMID:10920277 PMID:11504908 PMID:12372056 PMID:16014636 PMID:17576681 PMID:18767981 PMID:20085938 PMID:21103832 PMID:21194675 PMID:21659347 PMID:21824802 PMID:21828076 PMID:21956414 PMID:22703879 PMID:23161105 PMID:23442912 PMID:23555315 PMID:24033266 PMID:24055113 PMID:24728327 PMID:24763289 PMID:25157968 PMID:25186627 PMID:25669429 PMID:25741868 PMID:25980754 PMID:26467025 PMID:26580448 PMID:26619011 PMID:26795104 PMID:26800850 PMID:27428751 PMID:27477328 PMID:27535533 PMID:28135145 PMID:28492532 PMID:28677221 PMID:29706350 PMID:29785012 PMID:32350270 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 disease_progression ISO RGD PMID:18416056 RGD:2300125 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptk2 protein tyrosine kinase 2 severity ISO protein:increased expression:endometrium RGD PMID:15536334 RGD:2292562 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Rab26 RAB26, member RAS oncogene family ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,896,360...1,902,272 JBrowse link
G Rad51c RAD51 paralog C ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004936490:4,440,638...4,473,301 JBrowse link
G Rassf1 Ras association domain family member 1 ISO DNA, protein:hypermethylation, decreased expression:promoter, RGD PMID:18469797 RGD:2299863 NCBI chrNW_004936529:1,857,177...1,866,198 JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,784,396...1,794,269 JBrowse link
G Runx3 RUNX family transcription factor 3 ISO DNA:promoter:hypermethylated RGD PMID:18572225 RGD:2302555 NCBI chrNW_004936474:9,751,946...9,802,910 JBrowse link
G Sfn stratifin ISO RGD PMID:16271083 RGD:2299931 NCBI chrNW_004936474:11,274,927...11,279,427 JBrowse link
G Smad4 SMAD family member 4 severity ISO mRNA:decreased expression:endometrium
DNA:substitutions:promoter
RGD PMID:10331746 PMID:15385128 RGD:2299966 RGD:2300009 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO DNA, mRNA, protein:hypermethylation, altered expression RGD PMID:17487382 RGD:2300020 NCBI chrNW_004936515:11,026,156...11,046,812 JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Tacc3 transforming acidic coiled-coil containing protein 3 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936477:21,648,958...21,665,855 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 disease_progression ISO protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chrNW_004936502:13,345,936...13,350,170 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 disease_progression ISO mRNA:decreased expression:endometrium RGD PMID:17009991 RGD:2290360 NCBI chrNW_004936594:3,232,433...3,244,241 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 disease_progression ISO protein:increased expression:endometrium RGD PMID:12798711 RGD:2290420 NCBI chrNW_004936602:1,488,993...1,496,108 JBrowse link
G Tp53 tumor protein p53 severity ISO protein:increased expression:epithelial cell, endometrium
ClinVar Annotator: match by term: Endometrial carcinoma
DNA:mutations: :
RGD
ClinVar
PMID:18431720 PMID:25741868 PMID:26353976 RGD:11075084 RGD:2298525 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Traf7 TNF receptor associated factor 7 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,868,309...1,886,772 JBrowse link
G Tsc2 TSC complex subunit 2 ISO ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chrNW_004936694:1,958,152...1,993,373 JBrowse link
G Wnt2 Wnt family member 2 ISO mRNA:decreased expression:endometrium RGD PMID:9099960 RGD:2291875 NCBI chrNW_004936589:1,825,209...1,866,898 JBrowse link
G Wnt3 Wnt family member 3 ISO mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chrNW_004936541:1,943,260...1,985,829 JBrowse link
G Wnt4 Wnt family member 4 ISO mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
G Wnt5a Wnt family member 5A ISO mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chrNW_004936473:6,031,627...6,052,211 JBrowse link
endometrial hyperplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat containing 5 ISO protein:increased expression:endometrium RGD PMID:16803539 RGD:2298940 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Ca9 carbonic anhydrase 9 ISO protein:altered localization:membrane, endometrium RGD PMID:17452774 RGD:2298945 NCBI chrNW_004936524:3,672,393...3,678,630 JBrowse link
G Cdc25b cell division cycle 25B ISO protein:increased expression:endometrium RGD PMID:14559803 RGD:4105451 NCBI chrNW_004936485:14,897,050...14,914,034 JBrowse link
G Cdc25c cell division cycle 25C ISO RGD PMID:12931023 RGD:4105452 NCBI chrNW_004936531:7,471,722...7,499,781 JBrowse link
G Cdkn1c cyclin dependent kinase inhibitor 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22064387 NCBI chrNW_004936794:1,023,891...1,025,470 JBrowse link
G Celsr2 cadherin EGF LAG seven-pass G-type receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chrNW_004936704:779,528...803,860 JBrowse link
G Csrp1 cysteine and glycine rich protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chrNW_004936567:2,946,721...2,967,988 JBrowse link
G Ddx1 DEAD-box helicase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chrNW_004936493:14,884,532...14,918,621 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:19419940 RGD:2314912 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G LOC101960169 junction plakoglobin ISO protein:decreased expression:endometrium RGD PMID:12635138 RGD:2301747 NCBI chrNW_004936490:16,671,176...16,694,552 JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO protein:increased expression:endometrium RGD PMID:17352221 RGD:2298522 NCBI chrNW_004936551:5,388,456...5,395,071 JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402032 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO protein:increased expression:endometrium RGD PMID:15536334 RGD:2292562 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Skp2 S-phase kinase associated protein 2 ISO associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:16080017 RGD:2315043 NCBI chrNW_004936518:5,635,856...5,664,057 JBrowse link
Endometrial Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936548:4,983,461...5,110,693 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23146748 NCBI chrNW_004936579:1,312,175...1,328,397 JBrowse link
G Apc APC regulator of WNT signaling pathway ISO RGD PMID:24474556 RGD:13524584 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Arid1a AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Atr ATR serine/threonine kinase ISO ClinVar Annotator: match by term: Endometrial neoplasm ClinVar PMID:19470935 PMID:21228398 PMID:23144622 PMID:28492532 NCBI chrNW_004936540:4,074,543...4,178,859 JBrowse link
G Bcl2 BCL2 apoptosis regulator severity ISO RGD PMID:18386458 RGD:2298890 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Birc5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363521 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Calb2 calbindin 2 ISO protein:decreased expression:endometrium RGD PMID:18604736 RGD:2315881 NCBI chrNW_004936475:22,344,416...22,372,015 JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:endometrium
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18306533 PMID:29232554 RGD:2296034
G Cd44 CD44 molecule (Indian blood group) disease_progression ISO mRNA, protein:splice variant, increased expression:endometrium
protein:decreased expression:endometrium
RGD PMID:14658589 PMID:16308159 RGD:2289358 RGD:2296044 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Cd46 CD46 molecule ISO protein:increased expression:tumor:versus benign endometrium (p<0.0001) RGD PMID:10637067 RGD:2293548 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8075649 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdk2 cyclin dependent kinase 2 disease_progression ISO protein:increased expression:endometrium RGD PMID:17483252 RGD:2289230 NCBI chrNW_004936646:379,849...385,648 JBrowse link
G Cdk4 cyclin dependent kinase 4 disease_progression ISO protein:increased expression:endometrium RGD PMID:14648178 RGD:2299055 NCBI chrNW_004936646:1,886,262...1,889,260 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A susceptibility ISO DNA:polymorphism:cds:p.S31R
protein:increased expression:endometrium
RGD PMID:15099969 PMID:16837908 RGD:2289683 RGD:2296047 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:endometrium RGD PMID:15188025 RGD:2299090 NCBI chrNW_004936587:4,573,166...4,578,480 JBrowse link
G Cdkn1c cyclin dependent kinase inhibitor 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22064387 NCBI chrNW_004936794:1,023,891...1,025,470 JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chrNW_004936652:3,576,975...3,582,790 JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936709:1,183,243...1,214,144 JBrowse link
G Chfr checkpoint with forkhead and ring finger domains ISO CTD Direct Evidence: marker/mechanism CTD PMID:17143476 NCBI chrNW_004936660:2,725,019...2,754,564 JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29805589 NCBI chrNW_004936510:3,779,930...3,806,615 JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29805589 NCBI chrNW_004936474:9,019,044...9,020,110 JBrowse link
G Ctnna1 catenin alpha 1 disease_progression ISO RGD PMID:16803534 RGD:2298485 NCBI chrNW_004936531:7,865,907...8,036,020 JBrowse link
G Ctnnb1 catenin beta 1 disease_progression ISO protein:increased expression:nucleus
ClinVar Annotator: match by term: Endometrial neoplasm
RGD
ClinVar
PMID:9065402 PMID:9294210 PMID:10192393 PMID:16803534 PMID:17349568 PMID:25157968 PMID:26619011 RGD:2289828 RGD:2298485 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Dcn decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chrNW_004936507:7,887,259...7,923,055 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA,protein:decreased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO mRNA,protein:decreased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Egf epidermal growth factor severity ISO protein:increased expression:plasma (human) RGD PMID:25416211 RGD:13432197 NCBI chrNW_004936563:1,058,803...1,181,393 JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 severity
disease_progression
ISO DNA:amplification RGD PMID:17945336 PMID:18202752 RGD:2298490 RGD:2298491 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO protein:increased expression:endometrium RGD PMID:10537356 RGD:2298505 NCBI chrNW_004936646:497,783...515,247 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO protein:increased expression:endometrium RGD PMID:10537356 RGD:2298505 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:polymorphism:exon:p.R156R(human) RGD PMID:26349749 RGD:12880439 NCBI chrNW_004936706:1,816,561...1,829,638 JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24185510 NCBI chrNW_004936489:4,616,839...4,887,179 JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25437045 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21903722 NCBI chrNW_004936527:5,024,077...5,069,152 JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936689:2,261,163...2,449,951 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Endometrial neoplasm
DNA:SNP
DNA:mutations
CTD
ClinVar
RGD
PMID:7719344 PMID:8651276 PMID:8696350 PMID:9462761 PMID:9719378 PMID:10851026 PMID:11121055 PMID:11390973 PMID:12000365 PMID:12124745 PMID:12145519 PMID:12900900 PMID:14499350 PMID:15975938 PMID:16440883 PMID:16531735 PMID:17525745 PMID:18247426 PMID:18552176 PMID:18785201 PMID:20301628 PMID:20856019 PMID:21367659 PMID:21397175 PMID:21936542 PMID:22238366 PMID:22664175 PMID:23002168 PMID:23495007 PMID:23546041 PMID:24127277 PMID:24489893 PMID:25157968 PMID:25706251 PMID:25741868 PMID:25867380 PMID:25937001 PMID:26380986 PMID:26619011 PMID:27079505 PMID:28492532 PMID:31145570 RGD:2301188 RGD:2301189 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO protein:decreased expression:endometrium:loss of expression in 41/111 (37%) of tumors, significantly associated with poor survival and/or poor prognostic indicators RGD PMID:10873085 RGD:2289899 NCBI chrNW_004936473:397,140...1,424,805 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 disease_progression
severity
ISO protein:increased expression:endometrium
mRNA, protein:increased expression:endometrium
RGD PMID:10831352 PMID:12485477 RGD:2301252 RGD:2301256 NCBI chrNW_004936472:23,442,946...23,617,523 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO human cells in a mouse xenograft model RGD PMID:23941783 RGD:13441554 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Hdac1 histone deacetylase 1 disease_progression ISO RGD PMID:18714364 RGD:2306205 NCBI chrNW_004936474:15,320,635...15,351,418 JBrowse link
G Hdac2 histone deacetylase 2 disease_progression ISO RGD PMID:18714364 RGD:2306205 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Hoxa10 homeobox A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21670700 NCBI chrNW_004936478:3,798,679...3,802,007 JBrowse link
G Hoxa11 homeobox A11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chrNW_004936478:3,809,288...3,813,014 JBrowse link
G Hsd17b2 hydroxysteroid 17-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chrNW_004936475:29,426,922...29,494,215 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21442237 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO protein:decreased expression:plasma:significantly lower circulating levels in 80 cases vs 80 controls (p<0.001), significantly decreased risk in the highest quartile of expression RGD PMID:15159305 RGD:2290018 NCBI chrNW_004936478:20,511,490...20,518,251 JBrowse link
G Inha inhibin subunit alpha ISO mRNA:decreased expression:endometrium RGD PMID:15745937 RGD:1579943 NCBI chrNW_004936569:1,949,747...1,954,179 JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO RGD PMID:18691378 RGD:2299152 NCBI chrNW_004936485:8,857,688...8,894,270 JBrowse link
G Jazf1 JAZF zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18264096 NCBI chrNW_004936478:4,376,531...4,522,421 JBrowse link
G Kdr kinase insert domain receptor disease_progression ISO mRNA:increased expression:endometrium RGD PMID:11745191 PMID:12485477 RGD:2301252 RGD:2301760 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:19960433 RGD:2314907 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G Lasp1 LIM and SH3 protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28232485 NCBI chrNW_004936490:14,267,185...14,296,114 JBrowse link
G LOC101964975 interleukin-8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17380299 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G LOC101966403 speckle type BTB/POZ protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936490:11,894,449...11,969,730 JBrowse link
G LOC101968824 leucyl and cystinyl aminopeptidase ISO RGD PMID:15491750 RGD:2314921 NCBI chrNW_004936523:6,443,571...6,533,122 JBrowse link
G LOC101975820 cholesterol side-chain cleavage enzyme, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chrNW_004936471:33,367,810...33,380,764 JBrowse link
G Map3k4 mitogen-activated protein kinase kinase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936489:11,908,083...11,972,186 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:24917306 RGD:13441559 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO DNA:amplification RGD PMID:11719459 RGD:70557 NCBI chrNW_004936589:2,280,803...2,390,179 JBrowse link
G Mlh3 mutL homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936488:4,164,322...4,195,408 JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO protein:increased expression:endometrium RGD PMID:17009991 RGD:2290360 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Msh2 mutS homolog 2 ISO DNA, protein:mutation, decreased expression:endometrium RGD PMID:11920468 PMID:17925543 RGD:2293523 RGD:2298951 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Msh3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936469:82,967...275,772 JBrowse link
G Msh6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10508506 NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17301261 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26656844 NCBI chrNW_004936470:20,480,844...20,485,955 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20530669 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27348297 NCBI chrNW_004936505:7,886,327...7,966,969 JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase no_association ISO DNA:mutation:exon:p.S326C (1245C>G, rs1052133) (human) RGD PMID:22271435 PMID:22544315 RGD:8657377 RGD:8657379 NCBI chrNW_004936602:3,411,106...3,418,826 JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:15877079 NCBI chrNW_004936698:650,225...746,593 JBrowse link
G Pgr progesterone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chrNW_004936551:6,498,553...6,573,212 JBrowse link
G Phb prohibitin ISO protein:increased expression:endometrium RGD PMID:10421803 RGD:2292406 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO mRNA:increased expression:endometrium (human) RGD PMID:17427168 RGD:13441594 NCBI chrNW_004936540:907,118...1,041,814 JBrowse link
G Plxna3 plexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chrNW_004936809:1,209,787...1,226,726 JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23263490 NCBI chrNW_004936889:231,373...250,985 JBrowse link
G Pten phosphatase and tensin homolog severity ISO DNA:mutations:multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:loss of heterozygosity:cds: (human)
protein:decreased expression:endometrium
RGD
CTD
PMID:9326929 PMID:9354433 PMID:9765621 PMID:12888921 PMID:16402032 PMID:16804899 PMID:17317031 RGD:12832746 RGD:12832753 RGD:2292506 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression ISO RGD PMID:18416056 RGD:2300125 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO RGD PMID:14648178 RGD:2299055 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Rnf144b ring finger protein 144B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29724995 NCBI chrNW_004936552:4,080,675...4,165,882 JBrowse link
G Rnf43 ring finger protein 43 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25344691 NCBI chrNW_004936490:4,660,904...4,742,669 JBrowse link
G Sema3b semaphorin 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chrNW_004936529:1,806,535...1,818,352 JBrowse link
G Sema3f semaphorin 3F ISO CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chrNW_004936529:1,704,523...1,733,465 JBrowse link
G Six1 SIX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27259717 NCBI chrNW_004936495:4,839,496...4,842,906 JBrowse link
G Skp2 S-phase kinase associated protein 2 ISO RGD PMID:15220466 RGD:2315045 NCBI chrNW_004936518:5,635,856...5,664,057 JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chrNW_004936594:2,932,297...2,935,358 JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO RGD PMID:9891532 RGD:2300389 NCBI chrNW_004936504:6,975,044...6,981,304 JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chrNW_004936493:1,663,999...1,708,530 JBrowse link
G Srsf10 serine and arginine rich splicing factor 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21072693 NCBI chrNW_004936474:9,068,012...9,079,717 JBrowse link
G St14 ST14 transmembrane serine protease matriptase disease_progression ISO protein:increased expression:endometrium RGD PMID:19443387 RGD:2315087 NCBI chrNW_004936572:2,137,820...2,182,674 JBrowse link
G Star steroidogenic acute regulatory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chrNW_004936710:1,523,289...1,530,181 JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased tyrosine phosphorylation:endometrium RGD PMID:17311011 RGD:1643476 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25437045 NCBI chrNW_004936664:2,626,810...2,655,290 JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18264096 NCBI chrNW_004936538:2,921,987...2,971,521 JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA:increased expression:endometrium RGD PMID:11078809 RGD:2298562 NCBI chrNW_004936815:468,987...492,666 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 disease_progression ISO protein:increased expression:endometrium RGD PMID:12798711 RGD:2290420 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:20071162 NCBI chrNW_004936593:212,642...230,645 JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7955072 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Tp73 tumor protein p73 susceptibility ISO DNA:hypermethylation
DNA:polymorphism:exon
RGD PMID:15723718 PMID:16928264 RGD:2290585 RGD:2298528 NCBI chrNW_004936737:171,894...211,464 JBrowse link
G Tspyl2 TSPY like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chrNW_004936751:85,104...91,596 JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17380299 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18622689 NCBI chrNW_004936574:17,643...175,762 JBrowse link
endometrial serous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated susceptibility ISO DNA:deletion: :6174delT RGD PMID:16650962 RGD:2289045 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
endometrial stromal sarcoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:tumor:increased in 6/8 (75%) of tumors RGD PMID:17367465 RGD:2292170 NCBI chrNW_004936482:17,162,854...17,238,319 JBrowse link
Endometrioid Carcinomas term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 PMID:19418217 PMID:19487299 PMID:19853286 PMID:20233444 PMID:20453058 PMID:21464312 PMID:21512767 PMID:21793738 PMID:22538770 PMID:22610119 PMID:22722201 PMID:22722839 PMID:22980975 PMID:23237847 PMID:23348505 PMID:23700467 PMID:23728071 PMID:23934607 PMID:24190505 PMID:24657128 PMID:25157968 PMID:26619011 PMID:28492532 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Apc APC regulator of WNT signaling pathway ISO mRNA, protein:decreased expression:endometrium (human) RGD PMID:18570730 RGD:13432144 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Areg amphiregulin ISO mRNA, protein:increased expression:endometrium RGD PMID:16962163 RGD:2289950 NCBI chrNW_004936598:1,276,599...1,283,612 JBrowse link
G Atp7b ATPase copper transporting beta disease_progression ISO protein:increased expression:endometrium RGD PMID:15790435 RGD:2298864 NCBI chrNW_004936565:4,694,294...4,763,661 JBrowse link
G Birc5 baculoviral IAP repeat containing 5 ISO protein:increased expression:endometrium RGD PMID:16803539 RGD:2298940 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO RGD PMID:12782598 RGD:2296026 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Ca9 carbonic anhydrase 9 ISO protein:altered localization:membrane, endometrium RGD PMID:17452774 RGD:2298945 NCBI chrNW_004936524:3,672,393...3,678,630 JBrowse link
G Ccne1 cyclin E1 ISO protein:increased expression:endometrium RGD PMID:17483252 RGD:2289230 NCBI chrNW_004936570:5,536,817...5,547,880 JBrowse link
G Cdh1 cadherin 1 ISO protein:decreased expression:endometrium RGD PMID:18295959 RGD:2296045 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdk2 cyclin dependent kinase 2 severity ISO RGD PMID:9673386 RGD:2298990 NCBI chrNW_004936646:379,849...385,648 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO RGD PMID:17985331 RGD:2299091 NCBI chrNW_004936587:4,573,166...4,578,480 JBrowse link
G Chek2 checkpoint kinase 2 susceptibility ISO RGD PMID:17164260 RGD:2293868 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Ctnnb1 catenin beta 1 ISO DNA:mutations RGD PMID:17418409 RGD:2289817 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Daxx death domain associated protein ISO protein:increased expression:ovary: RGD PMID:23539629 RGD:9587820 NCBI chrNW_004936476:25,546,091...25,550,390 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Egfr epidermal growth factor receptor ISO mRNA:decreased expression:endometrium
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
RGD
ClinVar
PMID:16962163 PMID:22885469 RGD:2289950 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Eno2 enolase 2 ISO RGD PMID:18156975 RGD:2293737 NCBI chrNW_004936709:904,647...913,445 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:16962163 RGD:2289950 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:16962163 RGD:2289950 NCBI chrNW_004936646:497,783...515,247 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:16962163 RGD:2289950 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Esr1 estrogen receptor 1 severity ISO protein:increased phosphorylation RGD PMID:14559803 RGD:4105451 NCBI chrNW_004936489:4,616,839...4,887,179 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO DNA:mutations:exons,intron, splice site:varied mutations in different patients, mutations are somatic but identical germline mutations are associated with craniosynostosis and skeletal dysplasia syndromes
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
RGD
ClinVar
PMID:7719344 PMID:8651276 PMID:9462761 PMID:9719378 PMID:10851026 PMID:11121055 PMID:11390973 PMID:12124745 PMID:14499350 PMID:15975938 PMID:16440883 PMID:17525745 PMID:18552176 PMID:20301628 PMID:21367659 PMID:22238366 PMID:22664175 PMID:23002168 PMID:23495007 PMID:23546041 PMID:23908597 PMID:24489893 PMID:25157968 PMID:25741868 PMID:25867380 PMID:26380986 PMID:26619011 PMID:28492532 PMID:31145570 RGD:2289862 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 disease_progression ISO RGD PMID:17952116 RGD:2301465 NCBI chrNW_004936478:20,511,490...20,518,251 JBrowse link
G Inha inhibin subunit alpha ISO protein:decreased expression:tumor:significantly higher in normal compared to malignant tissue RGD PMID:17143484 RGD:2290368 NCBI chrNW_004936569:1,949,747...1,954,179 JBrowse link
G Inhba inhibin subunit beta A ISO protein:decreased expression:endometrium RGD PMID:16423381 RGD:2301688 NCBI chrNW_004936478:16,878,725...16,884,065 JBrowse link
G Kdr kinase insert domain receptor severity ISO protein:increased expression, increased phosphorylation:tumor:pKDR expression associated with poor overall survival (P=0.009) RGD PMID:16557278 RGD:2291929 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO associated with Ovarian Neoplasms RGD PMID:19542870 RGD:2314910 NCBI chrNW_004936548:2,078,568...2,113,877 JBrowse link
G LOC101968824 leucyl and cystinyl aminopeptidase ISO associated with Endometrial Neoplasms RGD PMID:15218296 RGD:2314922 NCBI chrNW_004936523:6,443,571...6,533,122 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:24917306 RGD:13441559 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:24917306 RGD:13441559 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO DNA:hypermethylation RGD PMID:17504987 RGD:2290483 NCBI chrNW_004936494:10,517,488...10,520,567 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO protein:decreased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO protein:increased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:21984976 NCBI chrNW_004936596:3,010,526...3,021,848 JBrowse link
G Pten phosphatase and tensin homolog ISO DNA:loss of heterozygosity, mutations:multiple (human)
DNA:mutations: :multiple
RGD PMID:11156411 PMID:17418409 RGD:12802357 RGD:2289817 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16633066 RGD:1581360 NCBI chrNW_004936905:148,956...156,023 JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO associated with Ovarian Neoplasms;protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chrNW_004936572:2,137,820...2,182,674 JBrowse link
G Wif1 WNT inhibitory factor 1 ISO mRNA:increased expression:ovary RGD PMID:16436637 RGD:2298535 NCBI chrNW_004936545:3,263,646...3,334,163 JBrowse link
endometriosis of uterus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase disease_progression ISO RGD PMID:31247078 RGD:124715471 NCBI chrNW_004936813:429,400...467,481 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:ectopic endometrium: RGD PMID:22572543 RGD:9588664 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO protein:decreased expression:endometrium: RGD PMID:22572543 RGD:9588664 NCBI chrNW_004936493:6,963,406...7,013,256 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO protein:increased expression:ectopic endometrium: RGD PMID:22572543 RGD:9588664 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
endometritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Casp6 caspase 6 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chrNW_004936563:912,502...920,025 JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chrNW_004936486:4,082,664...4,114,942 JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chrNW_004936474:3,178,097...3,196,130 JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:endometrium RGD PMID:25330821 RGD:11059518 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates ISO RGD PMID:31365951 RGD:126928127 NCBI chrNW_004936476:18,577,825...18,583,675 JBrowse link
epidermodysplasia verruciformis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmc6 transmembrane channel like 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Epidermodysplasia verruciformis
CTD
ClinVar
PMID:9536098 PMID:15042430 PMID:16199547 PMID:17139267 PMID:17576681 PMID:25741868 PMID:28492532 NCBI chrNW_004936594:2,743,466...2,759,482 JBrowse link
G Tmc8 transmembrane channel like 8 ISO ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:9536098 PMID:10084299 PMID:12426567 PMID:16045695 PMID:16199547 PMID:17576681 PMID:22158547 PMID:25741868 PMID:28492532 NCBI chrNW_004936594:2,760,649...2,768,438 JBrowse link
Epidermodysplasia Verruciformis 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmc6 transmembrane channel like 6 ISO OMIM NCBI chrNW_004936594:2,743,466...2,759,482 JBrowse link
G Tmc8 transmembrane channel like 8 ISO ClinVar Annotator: match by term: EPIDERMODYSPLASIA VERRUCIFORMIS, SUSCEPTIBILITY TO, 1 ClinVar PMID:12426567 PMID:22158547 PMID:25741868 PMID:28492532 NCBI chrNW_004936594:2,760,649...2,768,438 JBrowse link
Epidermodysplasia Verruciformis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmc8 transmembrane channel like 8 ISO OMIM NCBI chrNW_004936594:2,760,649...2,768,438 JBrowse link
Epidermodysplasia Verruciformis 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cib1 calcium and integrin binding 1 ISO OMIM NCBI chrNW_004936483:15,963,863...15,967,458 JBrowse link
Epidermodysplasia Verruciformis 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoh ras homolog family member H susceptibility ISO ClinVar Annotator: match by term: EPIDERMODYSPLASIA VERRUCIFORMIS, SUSCEPTIBILITY TO, 4 OMIM
ClinVar
PMID:22850876 NCBI chrNW_004936482:7,721,815...7,723,395 JBrowse link
Epidermodysplasia Verruciformis 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il7 interleukin 7 susceptibility ISO ClinVar Annotator: match by term: EPIDERMODYSPLASIA VERRUCIFORMIS, SUSCEPTIBILITY TO, 5 OMIM
ClinVar
PMID:25981006 NCBI chrNW_004936702:110,625...162,957 JBrowse link
gestational trophoblastic neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18440631 NCBI chrNW_004936837:827,568...838,933 JBrowse link
Hereditary Leiomyomatosis and Renal Cell Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chml CHM like Rab escort protein ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,833,921...8,844,484 JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936484:13,953,141...14,373,174 JBrowse link
G Exo1 exonuclease 1 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,570,488...8,627,004 JBrowse link
G Fh fumarate hydratase ISO OMIM NCBI chrNW_004936526:8,936,096...8,965,155 JBrowse link
G Fmn2 formin 2 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:9,832,790...10,169,488 JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:9,820,276...9,821,907 JBrowse link
G Kmo kynurenine 3-monooxygenase ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,877,085...8,928,280 JBrowse link
G Map1lc3c microtubule associated protein 1 light chain 3 gamma ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,492,840...8,497,028 JBrowse link
G Opn3 opsin 3 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,833,495...8,876,631 JBrowse link
G Pld5 phospholipase D family member 5 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,055,190...8,447,854 JBrowse link
G Rgs7 regulator of G protein signaling 7 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:9,087,820...9,552,482 JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Wdr64 WD repeat domain 64 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936526:8,689,313...8,821,950 JBrowse link
G Zp4 zona pellucida glycoprotein 4 ISO ClinVar Annotator: match by term: Hereditary leiomyomatosis and renal cell cancer ClinVar PMID:29909963 NCBI chrNW_004936484:15,370,443...15,376,564 JBrowse link
Hydatidiform Mole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide ISO protein:increased expression:serum RGD PMID:2473429 RGD:2293636 NCBI chrNW_004936510:4,679,349...4,696,511 JBrowse link
G Mlh1 mutL homolog 1 ISO DNA, protein:hypermethylation, decreased expression:promoter, mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO protein:increased expression:syncytiotrophoblast cell RGD PMID:16884384 RGD:2290363 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Msh2 mutS homolog 2 ISO DNA, protein:hypermethylation, decreased expression:promoter, mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO mRNA:increased expression:mononuclear cytotrophoblast cell RGD PMID:8504434 RGD:2292200 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
Hydatidiform Mole, Invasive term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msh2 mutS homolog 2 ISO protein:decreased expression:mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
Hydatidiform Mole, Recurrent, 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mei1 meiotic double-stranded break formation protein 1 ISO OMIM NCBI chrNW_004936492:196,829...277,052 JBrowse link
Hydatidiform Mole, Recurrent, 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH11orf80 chromosome unknown C11orf80 homolog ISO OMIM NCBI chrNW_004936599:2,798,185...2,875,995 JBrowse link
Kniest Like Dysplasia Lethal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspg2 heparan sulfate proteoglycan 2 ISO ClinVar Annotator: match by term: Lethal Kniest-like syndrome ClinVar PMID:11279527 PMID:24088041 PMID:24781210 PMID:25504735 PMID:25741868 PMID:25803036 PMID:26467025 PMID:26508570 PMID:26633545 PMID:28242392 PMID:28492532 PMID:29271572 PMID:29901129 NCBI chrNW_004936474:7,407,622...7,478,950 JBrowse link
G Ldlrad2 low density lipoprotein receptor class A domain containing 2 ISO ClinVar Annotator: match by term: Lethal Kniest-like syndrome ClinVar PMID:25504735 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chrNW_004936474:7,375,439...7,407,318 JBrowse link
McKusick-Kaufman syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mkks MKKS centrosomal shuttling protein ISO OMIM NCBI chrNW_004936485:9,089,118...9,114,396 JBrowse link
oligohydramnios term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inf2 inverted formin 2 ISO ClinVar Annotator: match by term: Oligohydramnios ClinVar PMID:25741868 NCBI chrNW_004936621:677,548...693,609 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO mRNA, protein:increased expression:lung RGD PMID:17519529 RGD:2292203 NCBI chrNW_004936754:808,894...828,554 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO mRNA, protein:increased expression:lung RGD PMID:17519529 RGD:2292203 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO mRNA:increased expression:lung RGD PMID:17519529 RGD:2292203 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO mRNA:increased expression:lung RGD PMID:17519529 RGD:2292203 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Pdpn podoplanin ISO mRNA, protein:decreased expression:lung RGD PMID:11839536 RGD:2292243 NCBI chrNW_004936474:1,751,159...1,779,011 JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin ISO ClinVar Annotator: match by term: Oligohydramnios ClinVar PMID:11898128 PMID:11919560 PMID:12506140 PMID:12846734 PMID:12874454 PMID:15108277 PMID:15108281 PMID:15696446 PMID:15805161 PMID:16133180 PMID:16199545 PMID:19914852 PMID:20413436 PMID:21274727 PMID:25124979 PMID:25741868 PMID:26695994 PMID:28375157 PMID:28492532 PMID:33532864 NCBI chrNW_004936476:8,730,766...9,160,102 JBrowse link
G Tmem67 transmembrane protein 67 ISO ClinVar Annotator: match by term: Oligohydramnios ClinVar PMID:19466712 PMID:19508969 PMID:19540516 PMID:19574260 PMID:20607301 PMID:21068128 PMID:21866095 PMID:23559409 PMID:25741868 PMID:26035863 PMID:26092869 PMID:28492532 NCBI chrNW_004936544:6,887,867...6,931,669 JBrowse link
papillomavirus infectious disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase RNA specific exacerbates ISO associated with human immunodeficiency virus infectious disease;DNA:SNPs, haplotype:introns, 3' utr: multiple (human) RGD PMID:31882741 RGD:125097510 NCBI chrNW_004936580:4,183,016...4,208,341 JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Ccna1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chrNW_004936472:30,574,957...30,586,596 JBrowse link
G Cd274 CD274 molecule ISO associated with cervix uteri carcinoma in situ; protein:increased expression:dendritic cell RGD PMID:23521696 RGD:40822817 NCBI chrNW_004936539:132,870...145,288 JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO associated with squamous cell carcinoma RGD PMID:31430224 RGD:38599177 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Foxp3 forkhead box P3 susceptibility ISO DNA:SNP::rs3761548(human) RGD PMID:31177386 RGD:38501104 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il1rl1 interleukin 1 receptor like 1 ISO RGD PMID:30935248 RGD:39938848 NCBI chrNW_004936713:1,020,969...1,035,012 JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association ISO DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:23444906 RGD:38501058 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Tlr3 toll like receptor 3 resistance ISO mRNA:increased expression:cervix epithelium (human) RGD PMID:20473890 RGD:5129102 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Vamp7 vesicle associated membrane protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chrNW_004936958:345,055...393,384 JBrowse link
placenta disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf2 insulin like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12087403 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Prss8 serine protease 8 ISO CTD Direct Evidence: therapeutic CTD PMID:24722141 NCBI chrNW_004936501:13,487,863...13,491,837 JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24722141 NCBI chrNW_004936801:1,041,946...1,069,617 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16007645 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
placental abruption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101972215 betaine--homocysteine S-methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17376725 NCBI chrNW_004936549:6,938,100...6,956,380 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15633187 NCBI chrNW_004936495:8,100,977...8,170,244 JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11354626 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa susceptibility ISO RGD PMID:9855597 RGD:11564329 NCBI chrNW_004936469:43,841,989...43,850,322 JBrowse link
placental insufficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO mRNA, protein:increased expression:placenta RGD PMID:20621762 RGD:5147460 NCBI chrNW_004936519:6,831,096...6,873,977 JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:20809703 RGD:10400897 NCBI chrNW_004936543:742,722...745,332 JBrowse link
G Gjb3 gap junction protein beta 3 ISO RGD PMID:11237463 RGD:12436730 NCBI chrNW_004936474:17,427,255...17,431,368 JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO mRNA, protein:altered expression:hippocampus (rat) RGD PMID:19144756 RGD:2326049 NCBI chrNW_004936669:814,330...838,881 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO protein:decreased expression:hippocampus (rat) RGD PMID:19144756 RGD:2326049 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO protein:increased expression:hippocampus (rat) RGD PMID:19144756 RGD:2326049 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Itga2 integrin subunit alpha 2 ISO mRNA:decreased expression:placenta (rat) RGD PMID:20621762 RGD:5147460 NCBI chrNW_004936480:14,320,292...14,417,828 JBrowse link
G LOC101954950 aromatase ISO mRNA, protein:altered expression:hippocampus (rat) RGD PMID:20662593 RGD:4890445 NCBI chrNW_004936471:13,107,603...13,136,910 JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO mRNA:increased expression:placenta (rat) RGD PMID:17893880 RGD:2311215 NCBI chrNW_004936472:23,102,534...23,107,127 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO mRNA, protein:decreased expression:gastrocnemius muscle (rat) RGD PMID:18319353 RGD:10059693 NCBI chrNW_004936477:4,881,230...5,488,208 JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:plasma: RGD PMID:26903689 RGD:11557202 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
polyhydramnios term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldn gliomedin ISO ClinVar Annotator: match by term: Polyhydramnios ClinVar PMID:25741868 PMID:27616481 PMID:28726266 PMID:31680349 NCBI chrNW_004936471:13,234,478...13,294,306 JBrowse link
G Igf2 insulin like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9349812 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO ClinVar Annotator: match by term: Polyhydramnios ClinVar PMID:15781747 PMID:15840476 PMID:19716085 PMID:19841300 PMID:22581653 PMID:22949429 PMID:23392653 PMID:24033266 PMID:24947509 PMID:25741868 PMID:25854863 PMID:26546361 PMID:27831900 PMID:28492532 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G LOC101968824 leucyl and cystinyl aminopeptidase ISO associated with Diabetes Mellitus RGD PMID:1789335 RGD:2311543 NCBI chrNW_004936523:6,443,571...6,533,122 JBrowse link
G Mtm1 myotubularin 1 ISO ClinVar Annotator: match by term: Polyhydramnios ClinVar PMID:25741868 NCBI chrNW_004936714:1,792,893...1,870,338 JBrowse link
G Piezo1 piezo type mechanosensitive ion channel component 1 ISO ClinVar Annotator: match by term: Polyhydramnios ClinVar PMID:25741868 PMID:30244526 PMID:31680349 NCBI chrNW_004936641:932,291...980,440 JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO ClinVar Annotator: match by term: Polyhydramnios ClinVar PMID:9718329 PMID:21394828 PMID:25741868 PMID:31680349 NCBI chrNW_004936479:16,350,746...16,374,911 JBrowse link
Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Strada STE20 related adaptor alpha ISO OMIM NCBI chrNW_004936541:4,352,613...4,385,499 JBrowse link
Progesterone Resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgr progesterone receptor ISO OMIM NCBI chrNW_004936551:6,498,553...6,573,212 JBrowse link
Recurrent Respiratory Papillomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule ISO protein:increased expression: larynx RGD PMID:22322668 RGD:40822813 NCBI chrNW_004936539:132,870...145,288 JBrowse link
G Foxp3 forkhead box P3 susceptibility ISO DNA:SNPs:promoter:rs5902434,rs2232365 (human) RGD PMID:28298239 RGD:38549360 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Nlrp1 NLR family pyrin domain containing 1 ISO OMIM NCBI chrNW_004936677:2,248,153...2,290,802 JBrowse link
G Pdcd1 programmed cell death 1 ISO RGD PMID:22322668 RGD:40822813 NCBI chrNW_004936745:152,571...163,712 JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member severity ISO DNA:polymorphism:cds:p.D637G(human) RGD PMID:14976605 RGD:5147844 NCBI chrNW_004936476:25,899,514...25,907,690 JBrowse link
Rhabdomyoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10908253 NCBI chrNW_004936493:7,060,747...7,065,276 JBrowse link
skin papilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 ISO protein:decreased expression:skin RGD PMID:21715145 RGD:7483622 NCBI chrNW_004936525:8,238,128...8,240,974 JBrowse link
G Clu clusterin ISO RGD PMID:11085517 RGD:8746700 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Fgf10 fibroblast growth factor 10 ISO protein:increased expression:skin (mouse) RGD PMID:24582960 RGD:126928134 NCBI chrNW_004936480:18,114,231...18,195,884 JBrowse link
G Nrg1 neuregulin 1 ISO DNA:hypermethylation: RGD PMID:31892232 RGD:39456089 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Tlr2 toll like receptor 2 ISO protein:increased expression,altered expression:cytoplasm,membrane, nucleus: RGD PMID:24617037 RGD:8553046 NCBI chrNW_004936576:522,234...531,660 JBrowse link
Squamous Intraepithelial Lesions of the Cervix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 severity ISO DNA:SNP::rs3761548(human) RGD PMID:31177386 RGD:38501104 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
subserous uterine fibroid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnrc6b trinucleotide repeat containing adaptor 6B severity ISO DNA:SNP: :rs12484776(human) RGD PMID:23892540 RGD:14394614 NCBI chrNW_004936492:1,461,572...1,697,500 JBrowse link
uterine cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A susceptibility ISO DNA:SNP:cds:p.F31I RGD PMID:17599395 RGD:2293873 NCBI chrNW_004936875:295,238...310,457 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 PMID:16187918 PMID:19206169 PMID:21639808 PMID:22048237 PMID:22495831 PMID:22663011 PMID:22972589 PMID:24033266 PMID:24451042 PMID:25157968 PMID:26619011 PMID:28492532 PMID:28832562 NCBI chrNW_004936592:4,728,371...4,833,830 JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 PMID:10027390 PMID:10192393 PMID:10391090 PMID:10398436 PMID:10435629 PMID:10655994 PMID:10666372 PMID:11351304 PMID:11930117 PMID:11950921 PMID:12124804 PMID:15133491 PMID:19234609 PMID:23265383 PMID:24788118 PMID:25157968 PMID:26619011 PMID:26822237 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 ISO protein:increased expression:serum RGD PMID:16842844 RGD:2289849 NCBI chrNW_004936470:35,449,920...35,473,635 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:16397024 PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:26619011 NCBI chrNW_004936646:497,783...515,247 JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:25741868 PMID:26619011 NCBI chrNW_004936689:2,261,163...2,449,951 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Malignant neoplasm of body of uterus ClinVar PMID:7719344 PMID:8651276 PMID:9462761 PMID:9719378 PMID:10851026 PMID:11121055 PMID:11390973 PMID:12124745 PMID:14499350 PMID:15975938 PMID:16440883 PMID:17525745 PMID:18552176 PMID:20301628 PMID:21367659 PMID:22238366 PMID:22664175 PMID:23002168 PMID:23495007 PMID:23546041 PMID:23908597 PMID:24489893 PMID:25157968 PMID:25741868 PMID:25867380 PMID:26380986 PMID:26619011 PMID:28492532 PMID:31145570 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Hras HRas proto-oncogene, GTPase ISO