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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:mood disorder
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Accession:DOID:3324 term browser browse the term
Definition:A cognitive disorder that involves a disturbance in mood as the predominant underlying feature. (DO)
Synonyms:exact_synonym: affective disorder;   affective disorders;   episodic mood disorder;   mood disorders
 primary_id: MESH:D019964
 xref: ICD10CM:F39;   NCI:C92200
For additional species annotation, visit the Alliance of Genome Resources.


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mood disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19691954 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adcy9 adenylate cyclase 9 no_association ISO DNA:polymorphisms:repeat,cds: RGD PMID:11840511 RGD:1358365 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29987918 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Avpr1b arginine vasopressin receptor 1B no_association ISO DNA:SNP: :rs28536160 (human)
DNA:SNP: :rs28373064, 35369693, rs28632197 (human)
RGD PMID:23962971, PMID:23962971 RGD:11528373, RGD:11528373 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Dctn1 dynactin subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19136952 NCBI chr 4:114,876,770...114,896,567
Ensembl chr 4:114,876,770...114,896,573
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IMP RGD PMID:22884333 RGD:9686419 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29921868 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit ISO
ISS
MouseDO PMID:16619054 RGD:8694301 NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
JBrowse link
G Rara retinoic acid receptor, alpha ISO RGD PMID:19596122 RGD:2314250 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878141 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25600109 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
bipolar disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEA GAD PMID:15118671 RGD:1331525 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Add3 adducin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:plasma RGD PMID:22137759 RGD:5686381 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570127 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO DNA:SNP, haplotype: :multiple (human) RGD PMID:20214684 RGD:5509071 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ank3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18711365 PMID:21926974 PMID:31043756 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO
ISS
MouseDO PMID:9646882 RGD:1358437 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO DNA:SNP: :rs28536160 (human) RGD PMID:24012103 RGD:14700651 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 PMID:19018715, PMID:15118671 RGD:1331525 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25395965 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Brd1 bromodomain containing 1 susceptibility ISO DNA,SNP,haplotype:3'UTR: RGD PMID:16924267 RGD:9586096 NCBI chr 7:129,676,119...129,724,303
Ensembl chr 7:129,676,120...129,724,303
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18711365 PMID:21926972 PMID:21926974 PMID:31043756 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28194001 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISS MouseDO NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO RGD PMID:15034225 RGD:1358456 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd47 Cd47 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:18391128 RGD:5688274 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP: :rs324650 (human)
protein:decreased expression:cerebral cortex
RGD PMID:20351719, PMID:19103464 RGD:5509579, RGD:5509584 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Clock clock circadian regulator ISS MouseDO NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11772685 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cplx1 complexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Cplx2 complexin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Ddc dopa decarboxylase ISO DNA:deletions:5' utr, intron:g.-601delG, g.722_725delGAGA (human) RGD PMID:12555230 RGD:1358586 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Disc1 DISC1 scaffold protein susceptibility ISO DNA;SNPs: :rs2738864,rs16841582 (human)
DNA:SNPs: :rs1538979, rs821577, rs821633 (human)
DNA:SNPs: :multiple
RGD PMID:21222298, PMID:18317464, PMID:15386212 RGD:5509829, RGD:5509836, RGD:5509833 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dixdc1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19153942 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd5 dopamine receptor D5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Fads2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fstl5 follistatin-like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:174,542,667...175,234,835
Ensembl chr 2:174,542,667...175,233,457
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 ISO DNA:repeat:intron:IVS8CA (human) RGD PMID:11840313 RGD:1358391 NCBI chr  X:152,414,332...152,642,607
Ensembl chr  X:152,414,615...152,642,531
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 ISO RGD PMID:9514592 RGD:1358630 NCBI chr 1:112,833,941...112,947,482
Ensembl chr 1:112,833,944...112,947,451
JBrowse link
G Gad1 glutamate decarboxylase 1 ISO protein:decreased expression:prefrontal cortex layers 2-5 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:15560956, PMID:18534564 RGD:6480428 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15560956 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO DNA:polymorphism RGD PMID:15909293 RGD:1601281 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18332879 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO DNA:repeat:promoter:(GT)18-33 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:31043756, PMID:12809987 RGD:1358644 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16549338 RGD:1642201 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO mRNA, protein:decreased expression:frontal cortex (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:12808434, PMID:19400979 RGD:5685029 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grn granulin precursor ISO protein:decreased expression:plasma RGD PMID:24581833 RGD:10401641 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20357757 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20357757, PMID:17357145, PMID:16397405 RGD:1641929, RGD:1641931 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IEA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:14708030, PMID:15118671 RGD:1331525 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO DNA:missense mutation:cds:p.C23S (human) RGD PMID:8823764 RGD:1358737 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Impa2 inositol monophosphatase 2 susceptibility ISO DNA:SNPs:promoter:-461C>T, -207T>C(human) RGD PMID:9322233, PMID:11673796, PMID:14699425 RGD:6480265, RGD:6480269, RGD:6480267 NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:5506046 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr16:7,012,376...7,026,542
Ensembl chr16:7,012,354...7,026,540
JBrowse link
G Kat6b lysine acetyltransferase 6B ISO DNA:mutations:multiple (human) RGD PMID:24444492 RGD:9588521 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G L1cam L1 cell adhesion molecule ISO associated with Depressive Disorder; mRNA:increased expression:blood (human) RGD PMID:18430502 RGD:6483084 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Lman2l lectin, mannose-binding 2-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 9:43,020,940...43,023,015
Ensembl chr 9:42,999,229...43,022,999
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:haplotype: : RGD PMID:24856568 RGD:12910826 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:67,606,971...67,616,056
Ensembl chr 4:67,607,273...67,610,710
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO DNA:missense mutation:cds:m.3644T>C (human) RGD PMID:15533721 RGD:5490261 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17074966 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO DNA:snps:introns:IVS6+32T>C, IVS7+11G>C, IVS12+21C>A (human) RGD PMID:15050861 RGD:1358750 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ncan neurocan ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr16:21,050,243...21,076,707
Ensembl chr16:21,050,243...21,076,707
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:20368511 RGD:6484696 NCBI chr 7:12,318,776...12,326,403
Ensembl chr 7:12,318,757...12,326,392
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19135101 NCBI chr 9:113,875,718...113,900,169
Ensembl chr 9:113,875,703...113,900,190
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrg1 neuregulin 1 ISO DNA:SNP:enhancer: (rs35753505) RGD PMID:18585932 RGD:39131291 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ntng1 netrin G1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17507910 NCBI chr 2:212,695,464...213,073,046
Ensembl chr 2:212,696,624...212,852,870
JBrowse link
G Ntng2 netrin G2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17507910 NCBI chr 3:7,742,511...7,800,834
Ensembl chr 3:7,742,531...7,796,385
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO protein:decreased expression:cerebellum
CTD Direct Evidence: marker/mechanism
CTD PMID:19018715, PMID:21612826 RGD:5684549 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:220,515,117...220,645,611
Ensembl chr 1:220,516,316...220,644,636
JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18394866 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:198,112,104...198,120,202
Ensembl chr 2:198,112,076...198,120,120
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit ISS MouseDO NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2843795 PMID:9664777 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pou3f2 POU class 3 homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 5:36,677,452...36,683,356
Ensembl chr 5:36,681,528...36,683,356
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B ISO DNA, mRNA:SNPs, haplotype, splice variant:multiple RGD PMID:23295814 RGD:13515076 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO mRNA, protein:decreased expression:prefrontal cortex RGD PMID:20038946 RGD:5688160 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO mRNA, protein:increased expression:prefrontal cortex RGD PMID:20038946 RGD:5688160 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pvalb parvalbumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA, protein:increased expression:dorsolateral prefrontal cortex (human) RGD PMID:16687443 RGD:5490162 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395
JBrowse link
G Reln reelin ISO protein:decreased expression:hippocampus (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:11126396 PMID:14708030 PMID:15560956, PMID:11126396 RGD:2324681 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G RT1-Da RT1 class II, locus Da ISO RGD PMID:16687443 RGD:5490162 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G S100b S100 calcium binding protein B IEP
ISO
protein:increased expression:cerebrospinal fluid
CTD Direct Evidence: marker/mechanism
CTD PMID:15581912 PMID:16476148, PMID:15581912 RGD:5508853 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659342 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Slc18a1 solute carrier family 18 member A1 ISO DNA:SNPs:5' utr, cds:g.-584A>G (rs988713), p.T136I (rs1390938) (human) RGD PMID:16936705 RGD:5131197 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183
JBrowse link
G Slc5a3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16420717 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism
DNA:repeats:promoter:
CTD PMID:11772685 PMID:16395126, PMID:10484962 RGD:36947381 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Snca synuclein alpha ISO RGD PMID:19198857 RGD:6478716 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sp4 Sp4 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19401786 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Srpk2 SRSF protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:7,994,025...8,187,455
Ensembl chr 4:8,066,737...8,185,935
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:18281098 RGD:11039413 NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:20,416,795...20,707,838
Ensembl chr 2:20,431,243...20,702,515
JBrowse link
G Sstr5 somatostatin receptor 5 ISO DNA:SNP, missense mutations, haplotype: :573G>A, p.L48M, p.P335L (human) RGD PMID:12192619 RGD:1358589 NCBI chr10:14,847,749...14,853,827
Ensembl chr10:14,847,749...14,853,827
JBrowse link
G Stard9 StAR-related lipid transfer domain containing 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:112,428,361...112,659,558
Ensembl chr 3:112,428,395...112,659,140
JBrowse link
G Stk4 serine/threonine kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 susceptibility ISO DNA:SNPs:promoter,intron: RGD PMID:28178086 RGD:13209005 NCBI chr 1:41,608,287...41,763,591
NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15845098 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19204064 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tenm4 teneurin transmembrane protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21926972 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:38,658,512...39,103,411
Ensembl chr 4:38,664,066...39,102,807
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:plasma RGD PMID:20861651 RGD:7205488 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO mRNA:increased expression:frontal association cortex
ClinVar Annotator: match by term: Bipolar affective disorder, susceptibility to
ClinVar PMID:17905754 PMID:19319927, PMID:16240163 RGD:5686358 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link
G Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 8:119,566,509...119,644,249
Ensembl chr 8:119,566,509...119,644,249
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23602965 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23602965 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Tshb thyroid stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:6455462 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Vwf von Willebrand factor ISO protein:increased expression:plasma RGD PMID:19839997 RGD:7207027 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr13:25,961,762...26,052,472
Ensembl chr13:25,966,428...26,013,338
JBrowse link
G Zfp592 zinc finger protein 592 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:142,833,999...142,870,997
Ensembl chr 1:142,834,157...142,870,995
JBrowse link
endogenous depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disc1 DISC1 scaffold protein ISS OMIM:608516 MouseDO NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISS OMIM:608516 MouseDO NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Hap1 huntingtin-associated protein 1 ISS OMIM:608516 MouseDO NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISS OMIM:608516 MouseDO NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Morc1 MORC family CW-type zinc finger 1 ISS OMIM:608516 MouseDO NCBI chr11:54,762,654...55,044,581
Ensembl chr11:54,762,654...55,044,581
JBrowse link
G Tph2 tryptophan hydroxylase 2 ISS OMIM:608516 MouseDO NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link
Major Affective Disorder 7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 susceptibility ISO ClinVar Annotator: match by term: Major affective disorder 7
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
major depressive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 susceptibility IEP protein: increased expression: cerebrospinal fluid RGD PMID:20580919 RGD:5128563 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 IEP protein:increased expression:blood serum (rat) RGD PMID:20580919 RGD:5128563 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Arrb1 arrestin, beta 1 severity ISO protein:decreased expression:blood, mononuclear cell RGD PMID:15514408 RGD:1578803 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:21803060 RGD:8655887 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Calm2 calmodulin 2 ISO mRNA:decreased expression:frontal association cortex RGD PMID:22885997 RGD:6892958 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP:3' utr:1890A>T (human)
protein:decreased expression:cerebral cortex
RGD PMID:12116189, PMID:19103464 RGD:1358507, RGD:5509584 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Cntnap2 contactin associated protein 2 susceptibility ISO DNA:SNPs: : rs2710102,rs2710117(human) RGD PMID:23123147 RGD:13450917 NCBI chr 4:74,700,539...77,025,463 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23529111 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 ISS OMIM:608520 | OMIM:608691 MouseDO NCBI chr16:20,740,746...20,798,145
Ensembl chr16:20,740,826...20,794,039
JBrowse link
G Ctnnd2 catenin delta 2 susceptibility ISO DNA:polymorphism:multiple (human) RGD PMID:24256404 RGD:40902831 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Disc1 DISC1 scaffold protein susceptibility ISO DNA:SNP:Cds:p.S704C(human)
protein:altered expression:orbitofrontal cortex
RGD PMID:16959794, PMID:15657124 RGD:5509832, RGD:5509834 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO mRNA:increased expression:dentated gyrus, hippocampus A1 RGD PMID:20953200 RGD:7771583 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B ISO protein:decreased expression:prefrontal cortex RGD PMID:21635931 RGD:11049139 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Major depressive disorder, increased recurrence of depressive episodes in, susceptibility to OMIM
ClinVar
PMID:15565110 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Foxp2 forkhead box P2 no_association ISO DNA:SNP: :rs10447760 (human)
DNA:SNPs: :multiple
RGD PMID:22404659, PMID:22404659 RGD:11535994, RGD:11535994 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26441752 NCBI chr19:30,973,329...31,032,331
Ensembl chr19:30,973,329...31,031,817
JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15560956 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15560956 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gal galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galr1 galanin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr18:79,243,009...79,258,570
Ensembl chr18:79,243,009...79,258,570
JBrowse link
G Galr2 galanin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Galr3 galanin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr 7:120,271,451...120,276,243
Ensembl chr 7:120,273,117...120,275,581
JBrowse link
G Gata1 GATA binding protein 1 ISO mRNA:increased expression:dorsolateral prefrontal cortex RGD PMID:22885997 RGD:6892958 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNP: :rs1043618 (human) RGD PMID:17428599 RGD:5147598 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO DNA:SNPs: :rs2075799, rs2227956 (human) RGD PMID:17428599 RGD:5147598 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO OMIM NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IDA mRNA:increased editing RGD PMID:16005997 RGD:1624993 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Ifi44l interferon-induced protein 44-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Il10 interleukin 10 ISO associated with Hepatitis C, Chronic;DNA:SNPs, haplotype:promoter:-592C>A, -���819C>T, -1082G>A (human) RGD PMID:30734130 RGD:14975122 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12635532 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 ISO mRNA: increased expression: BA10: frontal cortex RGD PMID:20479761 RGD:5686897 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il5 interleukin 5 ISO protein: increased expression: serum RGD PMID:22230487 RGD:5687135 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 ISO associated with Hepatitis C, Chronic;DNA:SNP, haplotype:promoter:-174G>C (human) RGD PMID:30734130 RGD:14975122 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Mc1r melanocortin 1 receptor ISO DNA:SNP:cds: rs885479,R163Q RGD PMID:21052032 RGD:5687198 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Med12 mediator complex subunit 12 ISO DNA:mutation:multiple RGD PMID:12216017 RGD:1358728 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:25001963 RGD:13825137 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:SNP:intron:IVS2+646C>G (human) RGD PMID:18246526 RGD:7174717 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nrg1 neuregulin 1 ISO mRNA:increased expression:prefrontal cortex RGD PMID:29295823 RGD:41404730 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 severity ISO mRNA:decreased expression:depression
DNA:SNPs: :rs2289657, rs56142442 (human)
DNA:SNPs: : (human)
RGD PMID:21223646, PMID:19844206, PMID:20124106 RGD:5684778, RGD:5684911, RGD:5684909 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO protein:decreased expression:brain: RGD PMID:20067857 RGD:9835359 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Reln reelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11126396 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Slc6a4 solute carrier family 6 member 4 treatment
susceptibility
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:repeats:promotor:
DNA:repeats:promoter:
DNA:hypomethylation:promoter:
DNA:SNPs, haplotypes:multiple
CTD PMID:16055263, PMID:12955294, PMID:15812265, PMID:24679990, PMID:19844206, PMID:27439447, PMID:12872203 RGD:39128240, RGD:38456009, RGD:36947871, RGD:5684911, RGD:36947384, RGD:36947382 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Syn1 synapsin I ISO mRNA:decreased expression:dorsolateral prefrontal cortex RGD PMID:22885997 RGD:6892958 NCBI chr  X:1,321,315...1,379,202
Ensembl chr  X:1,321,315...1,379,198
JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15845098 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO OMIM NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
mental depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:21914462 RGD:9588556 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO protein:increased expression, increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108178 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26860412 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra1a adrenoceptor alpha 1A ISO RGD PMID:19540213 RGD:5688369 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:20047711 RGD:6480482 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029664 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d treatment IDA RGD PMID:25641667 RGD:13800885 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Avpr1b arginine vasopressin receptor 1B treatment
no_association
IMP
ISO
associated with bipolar disorder;DNA:SNP: :multiple RGD PMID:24654684, PMID:26700241, PMID:23068076 RGD:14700666, RGD:14700672, RGD:14700671 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21308783 RGD:10054142 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP RGD PMID:21308783 RGD:10054142 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP
ISO
protein:decreased expression:brain
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:decreased expression:lymphocyte, platelet
CTD PMID:16330021 PMID:21945287, PMID:20920483, PMID:24128869, PMID:22097208, PMID:20227453 RGD:4891127, RGD:10059357, RGD:5684923, RGD:4891139 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 disease_progression
treatment
ISO RGD PMID:25386878, PMID:25386878 RGD:11561930, RGD:11561930 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Cadm1 cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Cat catalase ISO associated with gastric adenocarcinoma; protein:decreased expression:blood serum (human) RGD PMID:31396300 RGD:126908003 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IDA RGD PMID:21682945 RGD:13782377 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 NOT IEP RGD PMID:21682945 RGD:13782377 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 IEP mRNA:increased expression:brain RGD PMID:20830301 RGD:5509587 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18286196 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Crh corticotropin releasing hormone IEP
ISO
mRNA:increased expression:paraventricular nucleus, dorsal raphe nucleus (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12438692 PMID:18698320, PMID:20860876 RGD:5147490 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhbp corticotropin releasing hormone binding protein ISO
IEP
DNA:snps:intron, 3' utr:g.10661T>C, g.16113T>C (human)
protein:increased expression:hippocampus, frontal cortex (rat)
RGD PMID:14573312, PMID:19631474 RGD:1358530, RGD:5508785 NCBI chr 2:25,141,471...25,153,334
Ensembl chr 2:25,141,471...25,153,334
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP RGD PMID:20860876 RGD:5147490 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IEP RGD PMID:20860876 RGD:5147490 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Crp C-reactive protein ISO associated with kidney failure, chronic; protein:increased expression:plasma RGD PMID:22972567 RGD:6904211 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9018096 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP protein:increased expression:liver RGD PMID:20595028 RGD:4892242 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dbh dopamine beta-hydroxylase IEP protein:decreased expression:frontal cortex (rat) RGD PMID:19120095 RGD:5129527 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Disc1 DISC1 scaffold protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29643356 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dixdc1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO mRNA:increased expression:nucleus accumbens: RGD PMID:20729844 RGD:9589061 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Drd1 dopamine receptor D1 IEP mRNA:increased expression:caudate putamen (rat) RGD PMID:17558292 RGD:2311588 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 ISO
IEP
DNA:snp:cds:p.H313H (human)
mRNA:decreased expression:striatum
RGD PMID:9513185, PMID:21596067 RGD:1358603, RGD:6907449 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd5 dopamine receptor D5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Esr2 estrogen receptor 2 treatment IDA RGD PMID:24128867 RGD:10045672 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:30138765 RGD:13792497 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16861106 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16861106 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fth1 ferritin heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17063146 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17063146 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 ISO DNA:repeat:: (human) RGD PMID:9267853 RGD:1358629 NCBI chr 1:112,833,941...112,947,482
Ensembl chr 1:112,833,944...112,947,451
JBrowse link
G Gata1 GATA binding protein 1 ISO
IEP
mRNA:increased expression:prefrontal cortex RGD PMID:22885997, PMID:22885997 RGD:6892958, RGD:6892958 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:25340772 RGD:11049534 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272368 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Glo1 glyoxalase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gnb1 G protein subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gnb3 G protein subunit beta 3 susceptibility ISO DNA:SNP:cds: 825C>T (human) RGD PMID:12634518 RGD:1358639 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO RGD PMID:23707456 RGD:11352766 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20357757 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20357757 PMID:20534517, PMID:19815943 RGD:10045564 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hdac5 histone deacetylase 5 IEP protein:increased expression:hippocampus: RGD PMID:24495952 RGD:9681459 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:21512427, PMID:10578452 RGD:5683629, RGD:5683634 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IEA GAD PMID:15118671 RGD:1331525 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO RGD PMID:16487942 RGD:6480662 NCBI chr 8:53,247,881...53,278,170
Ensembl chr 8:53,248,705...53,277,859
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21859099, PMID:16828124 RGD:6482189 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
protein:increased expression:frontal cortex, hippocampus, hypothalamus (rat)
protein:increased expression:serum, hippocampus (mouse)
associated with gastric adenocarcinoma; protein:increased expression:blood serum (human)
RGD PMID:15000880, PMID:31396300, PMID:31396300 RGD:1626681, RGD:126908003, RGD:126908003 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO associated with Status Epilepticus; rat model treated with human protein RGD PMID:22427156 RGD:7174694 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 treatment IEP
ISO
mRNA:increased expression:colon
protein:increased expression:serum, hippocampus (mouse)
associated with gastric adenocarcinoma; protein:increased expression:blood serum (human)
associated with Chronic Hepatitis C; DNA:insertion/deletion:promoter:
associated with Hepatitis C, Chronic;DNA:SNP:promoter:-174G>C (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:hippocampus (rat)
CTD PMID:18458677, PMID:23589140, PMID:31396300, PMID:31396300, PMID:23571152, PMID:28083615, PMID:27106565 RGD:10402829, RGD:126908003, RGD:126908003, RGD:38676480, RGD:14975286, RGD:11062144 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor IEP mRNA:increased expression:colon RGD PMID:23589140 RGD:10402829 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:basolateral amygdala RGD PMID:10719210 RGD:2290593 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD PMID:21871532, PMID:16906152 RGD:9831184 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kmo kynurenine 3-monooxygenase IEP protein:decreased activity:plasma RGD PMID:29217494 RGD:13703051 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G L1cam L1 cell adhesion molecule IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:20018220 RGD:6483073 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO RGD PMID:25386878 RGD:11561930 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Mfn1 mitofusin 1 treatment ISO RGD PMID:22244747 RGD:13204844 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:22244747 RGD:13204844 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20177408 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO protein:increased expression:blood serum, hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17074966 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Ncam1 neural cell adhesion molecule 1 treatment IEP RGD PMID:29217494 RGD:13703051 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 susceptibility IEP RGD PMID:22311638 RGD:13801196 NCBI chr19:24,701,067...24,705,405
Ensembl chr19:24,701,049...24,705,405
JBrowse link
G Nefl neurofilament light chain IEP protein:decreased expression:dentate gyrus, hippocampus CA3 RGD PMID:17683840 RGD:2299053 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO protein:increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ngf nerve growth factor IEP mRNA:decreased expression:hippocampus RGD PMID:19129380 RGD:2303796 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor ISO DNA:SNP:CDS:p.S205L, minor (L) allele appears protective (human) RGD PMID:15274039 RGD:5508376 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos1 nitric oxide synthase 1 treatment ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:17854383, PMID:20571741 RGD:13824995 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein treatment IDA RGD PMID:19587612 RGD:7327168 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Depression ClinVar PMID:32581362 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Npy neuropeptide Y treatment ISO
IEP
IDA
DNA:snp, missense mutation:promoter, cds:g.-399T>C, p.L7P (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:hippocampus, prefrontal cortex
CTD PMID:9729278 PMID:17572454, PMID:14757324, PMID:22406386, PMID:19623606 RGD:1358535, RGD:10448940, RGD:10448937 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Npy1r neuropeptide Y receptor Y1 treatment IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:9729278, PMID:17265460, PMID:19623606, PMID:21803058 RGD:1642308, RGD:10448937, RGD:10448284 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Npy2r neuropeptide Y receptor Y2 treatment IMP RGD PMID:21803058 RGD:10448284 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:28763303 RGD:13439713 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP
ISO
mRNA:decreased expression:hippocampus (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:14708030, PMID:21837980 RGD:5686290 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO
IEP
RGD PMID:20956301, PMID:22097208 RGD:5684782, RGD:5684923 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA:decreased expression:striatum RGD PMID:21596067 RGD:6907449 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pde4d phosphodiesterase 4D IMP RGD PMID:22487514 RGD:7327149 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO mRNA:increased expression:blood RGD PMID:22331023 RGD:6482716 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18201294 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272368 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B treatment IDA RGD PMID:27457507 RGD:13514054 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19356723 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Reln reelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Ren renin ISO Associated with hypertension;protein:decreased activity:blood (human) RGD PMID:29960014 RGD:125097507 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Rnf103 ring finger protein 103 IDA RGD PMID:11071867 RGD:634523 NCBI chr 4:99,398,479...99,415,193
Ensembl chr 4:99,398,494...99,421,164
JBrowse link
G S100a10 S100 calcium binding protein A10 IEP
ISO
IDA
mRNA,protein:decreased expression:prefrontal cortex:
CTD Direct Evidence: marker/mechanism
DNA:hypermethylated:promoter:
CTD PMID:21682946, PMID:21682946, PMID:21682946 RGD:9588311, RGD:9588311 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:hippocampus RGD PMID:21843601 RGD:5508824 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:25451969 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Slc18a2 solute carrier family 18 member A2 ISO RGD PMID:17898223 RGD:5131168 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc6a2 solute carrier family 6 member 2 IEP RGD PMID:18800064 RGD:6218960 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility
severity
treatment
ISO
IMP
associated with Pulmonary Disease, Chronic Obstructive;DNA:SNP: :rs3794808 (human)
associated with Chronic Hepatitis C; DNA:insertion/deletion:promoter:
associated with Coronary Disease;DNA:repeats:promoter:
associated with breast cancer;DNA:repeat:promoter:
DNA:hypomethylation:promoter
associated with Radiation Injuries;DNA:repeats:promoter:
CTD Direct Evidence: marker/mechanism
CTD PMID:12898347 PMID:18458677 PMID:18686203 PMID:21843009, PMID:20981038, PMID:23571152, PMID:23096047, PMID:22134442, PMID:20664233, PMID:20808944, PMID:30582858, PMID:18295409 RGD:4889426, RGD:38676480, RGD:38456010, RGD:36947877, RGD:36947869, RGD:36947395, RGD:36947387, RGD:4889509 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Slc6a4m1Hubr solute carrier family 6 member 4; ZFN induced mutant1, Hubr IMP RGD PMID:18295409 RGD:4889509
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Snca synuclein alpha IEP
ISO
RGD PMID:18800064, PMID:19198857 RGD:6218960, RGD:6478716 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncg synuclein, gamma IEP RGD PMID:18800064 RGD:6218960 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19605942 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tg thyroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30373627 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Th tyrosine hydroxylase IEP mRNA,protein:decreased expression:hippocampus: RGD PMID:24495952 RGD:9681459 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO
IEP
mRNA,protein:decreased expression:hippocampus:
DNA:SNPs, haplotype:intron:218A>C, 779A>C (human)
RGD PMID:16165107, PMID:24495952, PMID:17134762 RGD:1580459, RGD:9681459, RGD:5686354 NCBI chr 1:102,669,868...102,699,442
Ensembl chr 1:102,669,868...102,699,442
JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17950541 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment IEP RGD PMID:32009956 RGD:127284856 NCBI chr 9:14,727,887...14,743,371
Ensembl chr 9:14,727,976...14,809,447
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein IEP RGD PMID:22311638 RGD:13801196 NCBI chr 7:71,264,501...71,269,869
Ensembl chr 7:71,264,514...71,269,869
Ensembl chr 1:71,264,514...71,269,869
JBrowse link
postpartum depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabrd gamma-aminobutyric acid type A receptor subunit delta ISS MouseDO NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353
JBrowse link
G Il10 interleukin 10 IEP RGD PMID:17033197 RGD:1598630 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO RGD PMID:15544576 RGD:1580465 NCBI chr 1:102,669,868...102,699,442
Ensembl chr 1:102,669,868...102,699,442
JBrowse link
Vascular Depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26286041 RGD:11073724 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17126
    disease of anatomical entity 16474
      nervous system disease 12073
        central nervous system disease 10352
          brain disease 9711
            disease of mental health 7018
              cognitive disorder 1946
                mood disorder 264
                  atypical depressive disorder 0
                  bipolar disorder + 113
                  dysthymic disorder 0
                  mental depression + 176
paths to the root