Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:bipolar disorder
go back to main search page
Accession:DOID:3312 term browser browse the term
Definition:A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Synonyms:exact_synonym: BPAD;   Bipolar and Related Disorders;   Mania;   Manias;   Manic Depressive Psychosis;   Manic Disorder;   bipolar affective disorder;   bipolar affective psychoses;   bipolar affective psychosis;   bipolar depression;   bipolar disorder manic phase;   bipolar disorders;   depressive-manic psych.;   manic bipolar I disorder;   manic bipolar affective disorder;   manic depression;   manic depressive disorder;   manic disorders;   manic state;   manic states;   manic-depressive psychoses;   mixed bipolar disorder
 related_synonym: BIPOLAR AFFECTIVE DISORDER, SUSCEPTIBILITY TO
 primary_id: MESH:D000068105;   MESH:D001714
 xref: GARD:10249;   ICD10CM:F31;   ICD10CM:F31.9;   ICD9CM:296.40;   ICD9CM:296.60;   ICD9CM:296.80;   NCI:C34423;   NCI:C34424;   NCI:C34805
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
bipolar disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACE angiotensin I converting enzyme JBrowse link 17 63,477,061 63,498,373 RGD:1331525
G ADCY2 adenylate cyclase 2 JBrowse link 5 7,396,138 7,830,081 RGD:11554173
G ADD3 adducin 3 JBrowse link 10 109,996,365 110,135,565 RGD:11554173
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 186,842,710 186,858,463 RGD:5686381
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,122 RGD:1331525
G AKR1C4 aldo-keto reductase family 1 member C4 JBrowse link 10 5,196,837 5,218,949 RGD:11554173
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:5509071
G ANK3 ankyrin 3 JBrowse link 10 60,026,298 60,733,528 RGD:11554173
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 19 41,966,582 41,994,230 RGD:1358437
RGD:13592920
G AVPR1B arginine vasopressin receptor 1B JBrowse link 1 206,106,936 206,117,388 RGD:14700651
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:1331525
RGD:11554173
G BHLHE40 basic helix-loop-helix family member e40 JBrowse link 3 4,979,420 4,985,323 RGD:11554173
G BRD1 bromodomain containing 1 JBrowse link 22 49,773,278 49,827,873 RGD:9586096
G CACNA1C calcium voltage-gated channel subunit alpha1 C JBrowse link 12 1,969,552 2,697,950 RGD:11554173
G CACNA1D calcium voltage-gated channel subunit alpha1 D JBrowse link 3 53,494,611 53,813,733 RGD:11554173
G CAMK2A calcium/calmodulin dependent protein kinase II alpha JBrowse link 5 150,219,491 150,290,130 RGD:13592920
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:1358456
G CD47 CD47 molecule JBrowse link 3 108,043,094 108,094,200 RGD:11554173
G CDC42 cell division cycle 42 JBrowse link 1 22,052,709 22,101,360 RGD:5688274
G CHRM2 cholinergic receptor muscarinic 2 JBrowse link 7 136,868,637 137,020,255 RGD:5509579
RGD:5509584
G CLOCK clock circadian regulator JBrowse link 4 55,427,901 55,547,138 RGD:13592920
G COMT catechol-O-methyltransferase JBrowse link 22 19,941,772 19,969,975 RGD:11554173
G CPLX1 complexin 1 JBrowse link 4 784,957 826,129 RGD:11554173
G CPLX2 complexin 2 JBrowse link 5 175,796,533 175,884,021 RGD:11554173
G DDC dopa decarboxylase JBrowse link 7 50,458,436 50,565,460 RGD:1358586
G DISC1 DISC1 scaffold protein JBrowse link 1 231,626,790 232,041,272 RGD:5509829
RGD:5509836
RGD:5509833
G DIXDC1 DIX domain containing 1 JBrowse link 11 111,927,144 112,022,653 RGD:11554173
G DRD1 dopamine receptor D1 JBrowse link 5 175,440,036 175,444,182 RGD:11554173
G DRD5 dopamine receptor D5 JBrowse link 4 9,781,634 9,784,009 RGD:11554173
G FADS2 fatty acid desaturase 2 JBrowse link 11 61,816,203 61,867,354 RGD:11554173
G FSTL5 follistatin like 5 JBrowse link 4 161,383,892 162,164,034 RGD:11554173
G GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 JBrowse link X 152,166,234 152,451,341 RGD:1358391
G GABRA5 gamma-aminobutyric acid type A receptor subunit alpha5 JBrowse link 15 26,867,062 26,949,210 RGD:1358630
G GAD1 glutamate decarboxylase 1 JBrowse link 2 170,813,210 170,861,151 RGD:6480428
RGD:11554173
G GAD2 glutamate decarboxylase 2 JBrowse link 10 26,216,307 26,304,562 RGD:11554173
G GCH1 GTP cyclohydrolase 1 JBrowse link 14 54,842,005 54,902,826 RGD:1601281
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 6 101,393,708 102,070,083 RGD:11554173
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 16 9,753,404 10,182,928 RGD:1358644
RGD:11554173
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 12 13,537,337 13,982,012 RGD:1642201
G GRK3 G protein-coupled receptor kinase 3 JBrowse link 22 25,564,675 25,729,294 RGD:5685029
RGD:11554173
G GRN granulin precursor JBrowse link 17 44,345,302 44,353,106 RGD:10401641
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 42,230,186 42,243,330 RGD:11554173
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:1641929
RGD:11554173
RGD:1641931
G HDAC5 histone deacetylase 5 JBrowse link 17 44,076,753 44,123,651 RGD:11554173
G HLA-DRA major histocompatibility complex, class II, DR alpha JBrowse link 6 32,439,887 32,445,046 RGD:5490162
G HTR2A 5-hydroxytryptamine receptor 2A JBrowse link 13 46,831,542 46,897,076 RGD:1331525
RGD:11554173
G HTR2C 5-hydroxytryptamine receptor 2C JBrowse link X 114,584,078 114,910,061 RGD:1358737
G IMPA2 inositol monophosphatase 2 JBrowse link 18 11,981,465 12,030,878 RGD:6480265
RGD:6480269
RGD:6480267
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:11554173
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 JBrowse link 3 52,777,599 52,792,068 RGD:11554173
G KAT6B lysine acetyltransferase 6B JBrowse link 10 74,824,927 75,032,624 RGD:9588521
G L1CAM L1 cell adhesion molecule JBrowse link X 153,861,514 153,886,173 RGD:6483084
G LMAN2L lectin, mannose binding 2 like JBrowse link 2 96,705,929 96,740,092 RGD:11554173
G MBL2 mannose binding lectin 2 JBrowse link 10 52,765,380 52,772,784 RGD:12910826
G MRPS33 mitochondrial ribosomal protein S33 JBrowse link 7 141,002,610 141,014,952 RGD:11554173
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 JBrowse link MT 3,307 4,262 RGD:5490261
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,785,723 11,806,103 RGD:11554173
G NCAM1 neural cell adhesion molecule 1 JBrowse link 11 112,961,420 113,278,436 RGD:1358750
G NCAN neurocan JBrowse link 19 19,211,958 19,252,233 RGD:11554173
G NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 JBrowse link 19 1,383,904 1,395,584 RGD:6484696
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 18 9,102,642 9,134,341 RGD:11554173
G NR3C1 nuclear receptor subfamily 3 group C member 1 JBrowse link 5 143,277,931 143,435,512 RGD:11554173
G NTNG1 netrin G1 JBrowse link 1 107,140,017 107,484,923 RGD:11554173
G NTNG2 netrin G2 JBrowse link 9 132,161,234 132,244,534 RGD:11554173
G NTRK1 neurotrophic receptor tyrosine kinase 1 JBrowse link 1 156,815,750 156,881,850 RGD:11554173
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,668,458 85,027,070 RGD:5684549
RGD:11554173
G PACS1 phosphofurin acidic cluster sorting protein 1 JBrowse link 11 66,070,272 66,244,744 RGD:11554173
G PC pyruvate carboxylase JBrowse link 11 66,848,420 66,958,418 RGD:11554173
G PDE4B phosphodiesterase 4B JBrowse link 1 65,792,510 66,374,579 RGD:11554173
G PLEKHO1 pleckstrin homology domain containing O1 JBrowse link 1 150,149,434 150,160,065 RGD:11554173
G POLG DNA polymerase gamma, catalytic subunit JBrowse link 15 89,316,320 89,334,824 RGD:13592920
G POMC proopiomelanocortin JBrowse link 2 25,160,853 25,168,851 RGD:11554173
G POU3F2 POU class 3 homeobox 2 JBrowse link 6 98,834,574 98,839,458 RGD:11554173
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B JBrowse link 17 39,626,735 39,636,625 RGD:13515076
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 122,369,906 122,395,703 RGD:5688160
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:5688160
G PVALB parvalbumin JBrowse link 22 36,800,703 36,819,499 RGD:11554173
G RAP1GAP RAP1 GTPase activating protein JBrowse link 1 21,596,221 21,669,444 RGD:5490162
G RELN reelin JBrowse link 7 103,471,784 103,989,658 RGD:2324681
RGD:11554173
G RIMS1 regulating synaptic membrane exocytosis 1 JBrowse link 6 71,886,703 72,403,145 RGD:11554173
G RPS6KA2 ribosomal protein S6 kinase A2 JBrowse link 6 166,409,364 166,862,525 RGD:11554173
G S100B S100 calcium binding protein B JBrowse link 21 46,598,604 46,605,243 RGD:5508853
RGD:11554173
G SCN2A sodium voltage-gated channel alpha subunit 2 JBrowse link 2 165,208,056 165,392,310 RGD:11554173
G SERPINA1 serpin family A member 1 JBrowse link 14 94,376,747 94,390,654 RGD:11554173
G SHANK2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 11 70,467,854 71,252,724 RGD:11554173
G SLC18A1 solute carrier family 18 member A1 JBrowse link 8 20,144,855 20,183,206 RGD:5131197
G SLC5A3 solute carrier family 5 member 3 JBrowse link 21 34,073,578 34,106,260 RGD:11554173
G SLC6A4 solute carrier family 6 member 4 JBrowse link 17 30,194,319 30,235,697 RGD:11554173
G SNAP25 synaptosome associated protein 25 JBrowse link 20 10,218,830 10,307,420 RGD:11554173
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:6478716
G SP4 Sp4 transcription factor JBrowse link 7 21,428,083 21,514,822 RGD:11554173
G SRPK2 SRSF protein kinase 2 JBrowse link 7 105,110,708 105,399,363 RGD:11554173
G SRSF3 serine and arginine rich splicing factor 3 JBrowse link 6 36,594,313 36,605,600 RGD:11039413
G SSBP2 single stranded DNA binding protein 2 JBrowse link 5 81,412,807 81,751,253 RGD:11554173
G SSTR5 somatostatin receptor 5 JBrowse link 16 1,072,756 1,081,454 RGD:1358589
G STARD9 StAR related lipid transfer domain containing 9 JBrowse link 15 42,575,606 42,720,998 RGD:11554173
G STK4 serine/threonine kinase 4 JBrowse link 20 44,966,470 45,080,021 RGD:11554173
G SYNE1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 6 152,121,684 152,637,395 RGD:13209005
G TAC1 tachykinin precursor 1 JBrowse link 7 97,732,086 97,740,472 RGD:11554173
G TACR1 tachykinin receptor 1 JBrowse link 2 75,046,463 75,199,520 RGD:11554173
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 78,652,829 79,441,030 RGD:11554173
G THSD7A thrombospondin type 1 domain containing 7A JBrowse link 7 11,370,365 11,832,198 RGD:11554173
G TNFRSF11B TNF receptor superfamily member 11b JBrowse link 8 118,923,557 118,951,885 RGD:7205488
G TPH2 tryptophan hydroxylase 2 JBrowse link 12 71,938,845 72,032,440 RGD:5686358
G TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 JBrowse link 3 36,826,817 36,945,662 RGD:11554173
G TRPC3 transient receptor potential cation channel subfamily C member 3 JBrowse link 4 121,874,481 121,952,060 RGD:11554173
G TRPM2 transient receptor potential cation channel subfamily M member 2 JBrowse link 21 44,350,112 44,443,081 RGD:11554173
G TSHB thyroid stimulating hormone subunit beta JBrowse link 1 115,029,826 115,035,935 RGD:11554173
G VWF von Willebrand factor JBrowse link 12 5,948,877 6,124,670 RGD:7207027
G ZCCHC2 zinc finger CCHC-type containing 2 JBrowse link 18 62,523,025 62,587,709 RGD:11554173
G ZNF592 zinc finger protein 592 JBrowse link 15 84,748,556 84,806,445 RGD:11554173
Major Affective Disorder 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G XBP1 X-box binding protein 1 JBrowse link 22 28,794,560 28,800,572 RGD:7240710
RGD:11554173
RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16990
    disease of anatomical entity 16013
      nervous system disease 12298
        central nervous system disease 10410
          brain disease 9612
            disease of mental health 7184
              cognitive disorder 2357
                mood disorder 234
                  bipolar disorder 112
                    Major Affective Disorder 3 0
                    Major Affective Disorder 4 0
                    Major Affective Disorder 5 0
                    Major Affective Disorder 6 0
                    Major Affective Disorder 7 1
                    Major Affective Disorder 8 0
                    Major Affective Disorder 9 0
                    Mental Health Wellness 1 0
                    Mental Health Wellness 2 0
                    bipolar I disorder + 0
                    bipolar ll disorder + 0
                    cyclothymic disorder 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.