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ONTOLOGY REPORT - ANNOTATIONS


Term:bipolar disorder
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Accession:DOID:3312 term browser browse the term
Definition:A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Synonyms:exact_synonym: BPAD;   Bipolar and Related Disorders;   Mania;   Manias;   Manic Bipolar Affective disorder;   Manic Depressive Psychosis;   Manic Depressive disorder;   Manic Disorder;   Manic Disorders;   Manic bipolar I disorder;   Manic-Depressive Psychoses;   bipolar affective disorder;   bipolar affective psychoses;   bipolar affective psychosis;   bipolar depression;   bipolar disorder manic phase;   bipolar disorders;   manic depression;   manic state;   manic states;   mixed bipolar disorder
 related_synonym: BIPOLAR AFFECTIVE DISORDER, SUSCEPTIBILITY TO;   Depressive-manic psych.
 primary_id: MESH:D000068105;   MESH:D001714
 alt_id: DOID:9007676
 xref: ICD10CM:F31;   ICD10CM:F31.9;   ICD9CM:296.40;   ICD9CM:296.60;   ICD9CM:296.80;   NCI:C34423;   NCI:C34424;   NCI:C34805
For additional species annotation, visit the Alliance of Genome Resources.


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bipolar disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:1331525
G Adcy2 adenylate cyclase 2 JBrowse link 1 37,043,071 37,698,390 RGD:11554173
G Add3 adducin 3 JBrowse link 1 273,854,195 273,961,982 RGD:11554173
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686381
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1331525
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:11554173
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:5509071
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:11554173
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 1 81,852,423 81,881,565 RGD:1358437
RGD:13592920
G Avpr1b arginine vasopressin receptor 1B JBrowse link 13 48,367,307 48,378,831 RGD:14700651
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1331525
RGD:8554872
RGD:11554173
G Bhlhe40 basic helix-loop-helix family, member e40 JBrowse link 4 140,703,619 140,709,319 RGD:11554173
G Brd1 bromodomain containing 1 JBrowse link 7 129,676,119 129,724,303 RGD:9586096
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:11554173
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:11554173
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:13592920
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:1358456
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:11554173
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:5688274
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:5509579
RGD:5509584
G Clock clock circadian regulator JBrowse link 14 34,418,226 34,502,218 RGD:13592920
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:11554173
G Cplx1 complexin 1 JBrowse link 14 2,194,895 2,226,610 RGD:11554173
G Cplx2 complexin 2 JBrowse link 17 10,756,871 10,828,811 RGD:11554173
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:1358586
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:5509829
RGD:5509836
RGD:5509833
G Dixdc1 DIX domain containing 1 JBrowse link 8 55,091,232 55,164,636 RGD:11554173
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:11554173
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:11554173
G Fads2 fatty acid desaturase 2 JBrowse link 1 225,906,582 226,152,568 RGD:11554173
G Fstl5 follistatin-like 5 JBrowse link 2 174,542,667 175,234,835 RGD:11554173
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 JBrowse link X 152,414,332 152,642,607 RGD:1358391
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 JBrowse link 1 112,833,941 112,947,482 RGD:1358630
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480428
RGD:11554173
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:11554173
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1601281
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:11554173
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1358644
RGD:11554173
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1642201
G Grk3 G protein-coupled receptor kinase 3 JBrowse link 12 49,626,871 49,750,389 RGD:5685029
RGD:11554173
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:10401641
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:11554173
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1641929
RGD:11554173
RGD:1641931
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:11554173
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:1331525
RGD:11554173
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:1358737
G Impa2 inositol monophosphatase 2 JBrowse link 18 63,016,577 63,050,123 RGD:6480265
RGD:6480269
RGD:6480267
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:11554173
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 JBrowse link 16 7,012,376 7,026,542 RGD:11554173
G Kat6b lysine acetyltransferase 6B JBrowse link 15 2,811,933 2,966,833 RGD:9588521
G L1cam L1 cell adhesion molecule JBrowse link X 156,901,244 156,928,064 RGD:6483084
G Lman2l lectin, mannose-binding 2-like JBrowse link 9 43,020,940 43,023,015 RGD:11554173
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:12910826
G Mrps33 mitochondrial ribosomal protein S33 JBrowse link 4 67,606,971 67,616,056 RGD:11554173
G Mt-nd1 mitochondrially encoded NADH dehydrogenase 1 JBrowse link MT 2,740 3,694 RGD:5490261
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:1358750
G Ncan neurocan JBrowse link 16 21,050,243 21,076,707 RGD:11554173
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 JBrowse link 7 12,318,776 12,326,403 RGD:6484696
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 9 113,875,718 113,900,169 RGD:11554173
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:11554173
G Ntng1 netrin G1 JBrowse link 2 212,695,464 213,073,046 RGD:11554173
G Ntng2 netrin G2 JBrowse link 3 7,742,511 7,800,834 RGD:11554173
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:11554173
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:5684549
RGD:11554173
G Pacs1 phosphofurin acidic cluster sorting protein 1 JBrowse link 1 220,515,117 220,645,611 RGD:11554173
G Pc pyruvate carboxylase JBrowse link 1 219,759,157 219,859,854 RGD:11554173
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:11554173
G Plekho1 pleckstrin homology domain containing O1 JBrowse link 2 198,112,104 198,120,202 RGD:11554173
G Polg DNA polymerase gamma, catalytic subunit JBrowse link 1 141,172,117 141,188,893 RGD:13592920
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:11554173
G Pou3f2 POU class 3 homeobox 2 JBrowse link 5 36,677,452 36,683,356 RGD:11554173
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:13515076
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:5688160
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5688160
G Pvalb parvalbumin JBrowse link 7 119,428,657 119,443,674 RGD:11554173
G Rap1gap Rap1 GTPase-activating protein JBrowse link 5 156,008,868 156,074,350 RGD:5490162
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:2324681
RGD:11554173
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:11554173
G Rps6ka2 ribosomal protein S6 kinase A2 JBrowse link 1 53,219,346 53,499,445 RGD:11554173
G RT1-Da RT1 class II, locus Da JBrowse link 20 4,127,644 4,132,616 RGD:5490162
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:5508853
RGD:11554173
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:11554173
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:11554173
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:11554173
G Slc18a1 solute carrier family 18 member A1 JBrowse link 16 22,358,646 22,395,183 RGD:5131197
G Slc5a3 solute carrier family 5 member 3 JBrowse link 11 32,229,366 32,231,812 RGD:11554173
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:11554173
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:11554173
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6478716
G Sp4 Sp4 transcription factor JBrowse link 6 146,135,877 146,201,344 RGD:11554173
G Srpk2 SRSF protein kinase 2 JBrowse link 4 7,994,025 8,187,455 RGD:11554173
G Srsf3 serine and arginine rich splicing factor 3 JBrowse link 20 6,288,285 6,298,218 RGD:11039413
G Ssbp2 single-stranded DNA binding protein 2 JBrowse link 2 20,416,795 20,707,838 RGD:11554173
G Sstr5 somatostatin receptor 5 JBrowse link 10 14,847,749 14,853,827 RGD:1358589
G Stard9 StAR-related lipid transfer domain containing 9 JBrowse link 3 112,428,361 112,659,558 RGD:11554173
G Stk4 serine/threonine kinase 4 JBrowse link 3 160,467,552 160,546,540 RGD:11554173
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209005
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:11554173
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:11554173
G Tenm4 teneurin transmembrane protein 4 JBrowse link 1 161,183,858 161,885,094 RGD:11554173
G Thsd7a thrombospondin type 1 domain containing 7A JBrowse link 4 38,658,512 39,103,411 RGD:11554173
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:7205488
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:5686358
G Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 JBrowse link 8 119,566,509 119,644,249 RGD:11554173
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 JBrowse link 2 123,329,954 123,467,574 RGD:11554173
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:11554173
G Tshb thyroid stimulating hormone subunit beta JBrowse link 2 205,207,799 205,215,199 RGD:11554173
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:7207027
G Zcchc2 zinc finger CCHC-type containing 2 JBrowse link 13 25,961,762 26,052,472 RGD:11554173
G Zfp592 zinc finger protein 592 JBrowse link 1 142,833,999 142,870,997 RGD:11554173
Major Affective Disorder 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:7240710
RGD:11554173

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Term Annotations click to browse term
  disease 15489
    disease of anatomical entity 14790
      nervous system disease 10147
        central nervous system disease 8254
          brain disease 7600
            disease of mental health 5554
              cognitive disorder 1847
                mood disorder 254
                  bipolar disorder 112
                    Major Affective Disorder 3 0
                    Major Affective Disorder 4 0
                    Major Affective Disorder 5 0
                    Major Affective Disorder 6 0
                    Major Affective Disorder 7 1
                    Major Affective Disorder 8 0
                    Major Affective Disorder 9 0
                    Mental Health Wellness 1 0
                    Mental Health Wellness 2 0
                    bipolar I disorder + 0
                    bipolar ll disorder + 0
                    cyclothymic disorder 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.