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ONTOLOGY REPORT - ANNOTATIONS


Term:chronic obstructive pulmonary disease
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Accession:DOID:3083 term browser browse the term
Definition:A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
Synonyms:exact_synonym: COAD;   COLD;   COPD;   Chronic Airflow Obstruction;   Chronic Airflow Obstructions;   Chronic Obstructive Airway Disease;   Chronic Obstructive Lung Disease
 narrow_synonym: PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, RATE OF DECLINE OF LUNG FUNCTION IN
 related_synonym: ANTICHYMOTRYPSIN BONN 1;   Pulmonary disease, chronic obstructive, susceptibility to
 primary_id: MESH:D029424
 alt_id: OMIM:606963;   RDO:0007473
 xref: ICD10CM:J44.9;   NCI:C3199
For additional species annotation, visit the Alliance of Genome Resources.


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chronic obstructive pulmonary disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:5128827
RGD:5128824
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:4140487
RGD:4140480
RGD:4140912
G Adam33 ADAM metallopeptidase domain 33 JBrowse link 3 123,595,018 123,607,549 RGD:4145361
RGD:4145358
RGD:4145357
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686379
RGD:5686825
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:4890385
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129114
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:5129114
RGD:4145082
RGD:4140935
RGD:4145080
RGD:4145095
RGD:4145093
RGD:4144899
RGD:4145086
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6767312
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:6892708
G Bambi BMP and activin membrane-bound inhibitor JBrowse link 17 56,905,419 56,909,675 RGD:14390164
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:11353864
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:4890451
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:11561985
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129504
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:5129705
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:5130165
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:13782182
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782303
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:13782303
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:4293707
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:4891410
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:4145389
G Ccl17 C-C motif chemokine ligand 17 JBrowse link 19 10,619,220 10,620,671 RGD:4145489
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:4891429
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:4145489
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:5130900
RGD:5130901
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:4891477
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483765
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314483
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:4145632
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892070
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:5131618
RGD:5131620
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:5490968
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:4892292
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892292
RGD:4891504
G Cd8a CD8a molecule JBrowse link 4 99,217,640 99,243,352 RGD:11554173
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:4140431
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:4892658
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:5133441
G Clca1 chloride channel accessory 1 JBrowse link 2 250,897,980 250,923,711 RGD:4145655
RGD:1331524
G Cma1 chymase 1 JBrowse link 15 34,601,037 34,603,819 RGD:5128552
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:5131854
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:11097322
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:5131278
RGD:5131279
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:5131476
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:4891499
RGD:4891504
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:4890939
RGD:11554173
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:5135436
G Cxcl11 C-X-C motif chemokine ligand 11 JBrowse link 14 17,195,395 17,198,170 RGD:5135436
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:11554173
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:11554173
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:5135248
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:4892070
RGD:5135436
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:5135248
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:5135435
RGD:4145632
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:4304108
RGD:4293707
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:4892071
RGD:11554173
RGD:4293707
RGD:4892045
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:4293707
RGD:11554173
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:4892219
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:13782182
G Defb1 defensin beta 1 JBrowse link 16 75,294,385 75,309,127 RGD:4892257
RGD:4892251
RGD:1331523
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:11554173
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4144868
RGD:4145062
G Eefsec eukaryotic elongation factor, selenocysteine-tRNA-specific JBrowse link 4 120,194,335 120,390,203 RGD:11554173
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131627
RGD:7204496
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131878
RGD:5131854
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:1580326
RGD:11554173
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4889120
RGD:8554872
RGD:11554173
RGD:4889121
RGD:1601065
RGD:4889122
RGD:4889123
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2289953
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:5147752
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:4892586
G Faim2 Fas apoptotic inhibitory molecule 2 JBrowse link 7 141,158,769 141,185,781 RGD:13792601
G Fam13a family with sequence similarity 13, member A JBrowse link 4 89,183,180 89,281,282 RGD:11552597
RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:13792601
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:13792601
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:5684420
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:11554173
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:1331525
RGD:5509932
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:4140939
RGD:4142517
RGD:4142538
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:4142517
RGD:4140938
RGD:4142511
RGD:4142514
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:4140939
RGD:4140928
G Gzma granzyme A JBrowse link 2 44,968,846 44,981,436 RGD:5135520
G Gzmb granzyme B JBrowse link 15 35,413,862 35,417,293 RGD:5135516
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:7204496
RGD:11554173
RGD:9590287
G Hdac8 histone deacetylase 8 JBrowse link X 72,163,777 72,370,058 RGD:13208820
G Hhip Hedgehog-interacting protein JBrowse link 19 31,525,134 31,614,487 RGD:11552597
RGD:11552598
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145372
RGD:10755705
RGD:7240710
RGD:4145371
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:5144151
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:8554872
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:8554872
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:8554872
G Hspa4 heat shock protein family A (Hsp70) member 4 JBrowse link 10 38,601,624 38,642,397 RGD:5688779
RGD:5688781
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:11554173
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:4145446
RGD:4145522
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:4145423
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145668
RGD:4145601
RGD:4145714
RGD:4145596
G Il13ra1 interleukin 13 receptor subunit alpha 1 JBrowse link X 122,724,081 122,783,801 RGD:4145601
G Il16 interleukin 16 JBrowse link 1 145,781,923 145,881,538 RGD:5024924
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4889104
RGD:9068943
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889551
RGD:4889575
G Il18bp interleukin 18 binding protein JBrowse link 1 167,091,521 167,095,727 RGD:4889551
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4142868
RGD:4143169
RGD:4142873
RGD:4142866
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:5144227
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4142868
RGD:4142861
RGD:4142866
G Il27 interleukin 27 JBrowse link 1 198,003,615 198,010,112 RGD:5128484
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:4890939
G Il5ra interleukin 5 receptor subunit alpha JBrowse link 4 138,796,165 138,834,164 RGD:5128619
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:4143243
RGD:11554173
G Il9 interleukin 9 JBrowse link 17 8,558,827 8,561,950 RGD:5128691
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:5684420
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:11554173
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:5128777
RGD:5128778
RGD:5128772
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:5128813
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:5490968
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:5490968
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:4889421
RGD:4889448
G Mcam melanoma cell adhesion molecule JBrowse link 8 48,472,824 48,481,005 RGD:7364780
G Mir218-2 microRNA 218-2 JBrowse link 10 20,428,661 20,428,770 RGD:11554173
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207216
RGD:8554872
RGD:7240710
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:11554173
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129553
RGD:13207319
RGD:11554173
RGD:5129494
RGD:5130149
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:5130997
RGD:5130993
G Mtcl1 microtubule crosslinking factor 1 JBrowse link 9 114,493,901 114,632,632 RGD:11554173
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:5131160
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:4145655
RGD:7349406
RGD:5131190
G Muc5b mucin 5B, oligomeric mucus/gel-forming JBrowse link 1 214,778,459 214,811,237 RGD:5131169
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:4892219
RGD:5131863
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:5134980
RGD:10412732
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:5508720
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:5132628
RGD:5132607
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891444
RGD:11554173
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:11554173
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:5134980
RGD:13439712
RGD:5133267
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:4892318
RGD:4892564
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:4891120
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:5684530
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6483803
RGD:6484146
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6484146
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:8547571
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6484530
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135277
RGD:5143926
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:11554173
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:6478682
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:4140387
RGD:8554872
RGD:11554173
RGD:7240710
G Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M JBrowse link 6 127,808,785 127,816,067 RGD:8554872
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N JBrowse link 6 128,073,344 128,080,878 RGD:5147433
RGD:5147449
RGD:5147441
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:4144041
RGD:6484146
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4143288
RGD:4143281
RGD:4143423
G Sftpb surfactant protein B JBrowse link 4 100,166,855 100,175,941 RGD:4143402
RGD:4143396
RGD:4143423
RGD:4143290
G Sftpc surfactant protein C JBrowse link 15 52,211,538 52,214,480 RGD:4144115
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143501
RGD:11554173
RGD:4143281
RGD:4143487
RGD:4143492
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:4889426
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:9999419
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:9999419
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10041059
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:1581270
RGD:11554173
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:8661725
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:4145292
RGD:11554173
RGD:4145140
RGD:4145115
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:13207319
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144145
RGD:4144119
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143273
RGD:11554173
RGD:4143424
RGD:4143421
RGD:4143270
RGD:4143272
RGD:4145714
RGD:4143391
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:5131203
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5131154
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:5684420
RGD:10755705
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:8698653
Bronchitis, Chronic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:4145442
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:4140484
RGD:4140475
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:4891509
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:4142512
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:4889126
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4145074
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:5129516
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:4142513
RGD:12798508
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:4142512
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:2308951
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:2308951
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4759835
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:4990461
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:5130990
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891494
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173
Chronic Obstructive Pulmonary Disease, Severe Early-Onset term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:8554872
pulmonary emphysema term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686887
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:11554173
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:11035274
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 JBrowse link 3 114,869,478 114,880,218 RGD:13592920
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:4145393
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:4891458
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892098
RGD:4892090
RGD:4892104
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:4892658
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039438
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:4891888
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5135245
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:4892104
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:5135245
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:5135245
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:4892104
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:4892104
G Defb1 defensin beta 1 JBrowse link 16 75,294,385 75,309,127 RGD:4892249
G Dhx34 DExH-box helicase 34 JBrowse link 1 78,069,260 78,112,488 RGD:8554872
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:4892307
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131973
RGD:5131853
RGD:5131892
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450557
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:11554173
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4140935
RGD:11554173
RGD:4889405
RGD:1601065
RGD:4889406
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:13592920
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:11040553
G Fut8 fucosyltransferase 8 JBrowse link 6 100,305,957 100,537,208 RGD:13592920
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:5134681
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:4140927
G Gstm3 glutathione S-transferase mu 3 JBrowse link 2 210,685,204 210,688,273 RGD:5135041
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:4140935
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590245
RGD:9590320
G Hhip Hedgehog-interacting protein JBrowse link 19 31,525,134 31,614,487 RGD:11552596
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601606
RGD:11554173
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145652
G Il17ra interleukin 17 receptor A JBrowse link 4 152,995,865 153,018,394 RGD:5144212
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889590
RGD:8655969
G Itgb6 integrin subunit beta 6 JBrowse link 3 46,652,624 46,775,362 RGD:737734
RGD:11554173
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:13592920
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:5134973
RGD:6893395
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:13592920
G Lox lysyl oxidase JBrowse link 18 47,500,320 47,577,819 RGD:8554872
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:4890375
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:4892307
RGD:11554173
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:4892307
RGD:11554173
RGD:8547887
RGD:5130151
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:13592920
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:5134973
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:4891488
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891488
RGD:5509103
RGD:4891415
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:4891415
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:5134973
G Pgf placental growth factor JBrowse link 6 108,994,016 109,004,598 RGD:5135245
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:7242020
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:4891488
G Ptma prothymosin alpha JBrowse link 9 93,545,396 93,549,436 RGD:13592920
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:4892126
RGD:11554173
RGD:4892125
G Sftpc surfactant protein C JBrowse link 15 52,211,538 52,214,480 RGD:4144115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:13592920
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10041059
G Srfbp1 serum response factor binding protein 1 JBrowse link 18 47,456,406 47,478,967 RGD:8554872
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:5147818
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:4145272
RGD:11554173
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:4145342
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144170
RGD:13592920
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15489
    disease of anatomical entity 14790
      respiratory system disease 2405
        lung disease 1400
          obstructive lung disease 417
            chronic obstructive pulmonary disease 199
              Bronchitis, Chronic 17
              Chronic Obstructive Pulmonary Disease, Severe Early-Onset 1
              Mucus Inspissation of Respiratory Tract 0
              pulmonary emphysema + 65
Path 2
Term Annotations click to browse term
  disease 15489
    disease of anatomical entity 14790
      respiratory system disease 2405
        lower respiratory tract disease 1441
          lung disease 1400
            obstructive lung disease 417
              chronic obstructive pulmonary disease 199
                Bronchitis, Chronic 17
                Chronic Obstructive Pulmonary Disease, Severe Early-Onset 1
                Mucus Inspissation of Respiratory Tract 0
                pulmonary emphysema + 65
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.