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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:brain glioblastoma multiforme
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Accession:DOID:3073 term browser browse the term
Definition:A brain glioma that has_material_basis_in abnormally proliferating cells derives_from glial cells, has_symptom seizure, headaches, nausea and vomiting, memory loss, changes to personality, mood or concentration; and localized neurological problems. (DO)
Synonyms:exact_synonym: brain glioblastoma;   glioblastoma multiforme of brain
 primary_id: RDO:9002207
 xref: NCI:C4642
For additional species annotation, visit the Alliance of Genome Resources.



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brain glioblastoma multiforme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir139 microRNA 139 ISO RNA:decreased expression:brain: RGD PMID:26449464 RGD:13838722 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902
JBrowse link
G Ncam1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:20219118 RGD:40924672 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17240
    disease of cellular proliferation 7045
      cancer 5000
        cell type cancer 3406
          high grade glioma 625
            brain glioma 22
              brain glioblastoma multiforme 2
Path 2
Term Annotations click to browse term
  disease 17240
    disease of cellular proliferation 7045
      Neoplasms by Site 6687
        Nervous System Neoplasms 1691
          Central Nervous System Neoplasms 1366
            Brain Neoplasms 1308
              Supratentorial Neoplasms 441
                supratentorial cancer 441
                  cerebrum cancer 389
                    malignant astrocytoma 385
                      glioblastoma 154
                        brain glioblastoma multiforme 2
paths to the root