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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:acute kidney failure
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Accession:DOID:3021 term browser browse the term
Definition:Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Synonyms:exact_synonym: Acute Kidney Failures;   Acute Kidney Injuries;   Acute Kidney Injury;   Acute Kidney Insufficiencies;   Acute Kidney Insufficiency;   Acute Renal Failure;   Acute Renal Failures;   Acute Renal Injuries;   Acute Renal Injury;   Acute Renal Insufficiencies;   Acute Renal Insufficiency
 narrow_synonym: post-operative acute kidney injury;   postoperative acute kidney injury
 primary_id: MESH:D058186;   RDO:0001702
 xref: EFO:0009955
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
acute kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Ace angiotensin I converting enzyme treatment ISO RGD PMID:24502693 RGD:11039053 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 treatment ISO associated with endotoxemia; protein:increased expression:kidney
associated with Endotoxemia;
associated with Bacteremia;		 RGD PMID:14747378 PMID:19020966 PMID:19887504 PMID:14747378 RGD:7175276, RGD:7175283, RGD:7175281, RGD:7175276 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Afm afamin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21811803 RGD:7243868 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase ISO protein:decreased activity:kidney (rat) RGD PMID:19484701 RGD:4144146 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2048579 PMID:21259293 PMID:24361871 PMID:28885000 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:19194548 RGD:2317536 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:8963945 PMID:28885000 PMID:8963945 RGD:6904218 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036 		JBrowse link
G Amn amnionless ISO CTD Direct Evidence: therapeutic CTD PMID:20514524 NCBI chr12:111,237,530...111,242,860
Ensembl chr12:111,237,529...111,242,860 		JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:22101490 RGD:7421583 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Ar androgen receptor ISO RGD PMID:24503548 RGD:11570523 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arg1 arginase, liver ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Arg2 arginase type II ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25666834 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2139164 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:17347933 RGD:2300348 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc disease_progression ISO RGD PMID:23849457 RGD:153350150 NCBI chr 5:137,979,783...137,988,495
Ensembl chr 5:137,979,782...137,988,495 		JBrowse link
G B2m beta-2 microglobulin ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:2689182 PMID:22005293 PMID:28885000 PMID:19536607 RGD:6482685 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO RGD PMID:20037173 RGD:10053672 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20623750 PMID:20037173 RGD:10053672 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24975837 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496 		JBrowse link
G C3 complement component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Capn1 calpain 1 treatment ISO associated with Rhabdomyolysis; RGD PMID:24158126 RGD:13792553 NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927 		JBrowse link
G Casp1 caspase 1 ISO RGD PMID:16557226 RGD:2293624 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP protein:increased expression:kidney RGD PMID:22778179 RGD:7247739 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:20482449 RGD:6906908 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP protein:increased secretion:serum (mouse) RGD PMID:19508392 RGD:4889990 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26055553 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457 		JBrowse link
G Cd44 CD44 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:kidney RGD PMID:16557226 RGD:2293624 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Ces1c carboxylesterase 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 8:93,825,643...93,857,911
Ensembl chr 8:93,825,643...93,857,911 		JBrowse link
G Clu clusterin ISO protein:increased expression:urine
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20118187 PMID:20623750 PMID:22005293 PMID:23052191 PMID:24361871 More... RGD:7245501 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum
associated with Myocardial Infarction;		 RGD PMID:22551254 PMID:22694718 RGD:6903282, RGD:6906888 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IMP RGD PMID:23143303 RGD:7257565 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:23143303 RGD:7257565 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Cst3 cystatin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 PMID:28885000 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:kidney, liver, spleen RGD PMID:21677145 RGD:7175314 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 treatment IDA RGD PMID:19890363 PMID:18495746 RGD:7257732, RGD:7257735 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 treatment IDA RGD PMID:23981375 PMID:18495746 RGD:7257727, RGD:7257735 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO RGD PMID:6223803 RGD:2307326 NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 treatment ISO RGD PMID:24717297 PMID:24412858 RGD:14700914, RGD:14700920 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO Protein:increased expression:renal tubule epithelium RGD PMID:15476864 RGD:1599736 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 ameliorates IDA RGD PMID:19828677 RGD:155663373 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:11043448 PMID:10073607 RGD:7244180, RGD:7244185 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540 		JBrowse link
G Edn1 endothelin 1 IEP
ISO		 mRNA, protein:increased expression:kidney (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9788586 PMID:19967049 RGD:4144852 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Egf epidermal growth factor ISO mRNA:decreased expression:kidney RGD PMID:20482449 PMID:11340354 RGD:6906908, RGD:10395241 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egfr epidermal growth factor receptor ISO mRNA:increased expression:kidney
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:14638913 PMID:11340354 RGD:10395241 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646 		JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO RGD PMID:16762988 RGD:10395386 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO CTD Direct Evidence: therapeutic CTD PMID:26165641 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21847101 PMID:24561306 PMID:22209169 PMID:22235348 RGD:10400913, RGD:11041660 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:renal tubule (rat) RGD PMID:21374789 RGD:8663469 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA:increased expression:kidney (rat) RGD PMID:15805072 RGD:9685024 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fis1 fission, mitochondrial 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:kidney RGD PMID:12884040 PMID:11768240 RGD:7205684, RGD:729934 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fstl1 follistatin-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20861081 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:602954 PMID:734759 PMID:4794122 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19564549 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490 		JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) ISO protein:decreased activity:kidney (rat) RGD PMID:2752493 RGD:1599823 NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784 		JBrowse link
G Gc vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:cortex of kidney,renal medulla:
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:20030531 PMID:20030531 PMID:20030531 RGD:9685736, RGD:9685736 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,130 		JBrowse link
G Ghrl ghrelin IDA RGD PMID:19625378 RGD:7242430 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial ISO protein:decreased activity:kidney (rat) RGD PMID:23924727 RGD:13506245 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175 		JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble treatment ISO RGD PMID:22209169 RGD:10400913 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:decreased expression:kidney RGD PMID:36583727 RGD:401827125 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gpx4 glutathione peroxidase 4 treatment ISO RGD PMID:29548851 RGD:401827911 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22785175 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsr glutathione reductase ISO
IEP		 glycerol-induced
protein:decreased activity:kidney:		 RGD PMID:1870354 PMID:22286819 RGD:7257559, RGD:7257585 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20623750 PMID:20798258 RGD:6903954 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
IEP		 protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
protein:increased expression:urine:
associated with Pyelonephritis;protein:increased expression:urine:		 CTD
RGD		 PMID:20118187 PMID:21259293 PMID:21835770 PMID:22005293 PMID:23052191 More... RGD:7244370, RGD:7245495, RGD:7245472 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7635938 PMID:11340354 RGD:10395241 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hdac2 histone deacetylase 2 treatment IEP associated with sepsis; RGD PMID:22933299 RGD:9590257 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:21416250 RGD:10047111 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069 		JBrowse link
G Hdac5 histone deacetylase 5 treatment IEP
ISO		 associated with sepsis; RGD PMID:22933299 PMID:21416250 RGD:9590257, RGD:10047111 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO mRNA:increased expression:kidney collecting duct (rat)
protein:increased expression:kidney tubule (rat)		 RGD PMID:24397211 PMID:24325066 RGD:9685383, RGD:9685389 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Hexb hexosaminidase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment ISO mRNA:increased expression:renal cortex (rat) RGD PMID:18593636 PMID:16762988 PMID:15673301 RGD:9068894, RGD:10395386, RGD:10395376 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36052886 NCBI chr 3:103,647,131...103,699,210
Ensembl chr 3:103,647,131...103,698,879 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase IMP associated with Sepsis RGD PMID:16557230 RGD:5508471 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO associated with Sepsis
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:21048024 PMID:23807243 RGD:10755583 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28885000 PMID:19270397 RGD:11041863 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344 		JBrowse link
G Hspa1a heat shock protein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12690470 PMID:19546256 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa8 heat shock protein 8 ISO protein:increased expression:kidney, lysosome (rat) RGD PMID:14966137 RGD:7242786 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:22659586 RGD:7175102 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO mRNA: decreased expression: kidney: both cortex and medulla RGD PMID:9767523 RGD:7242908 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18460982 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:11342578 RGD:6893450 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha IMP RGD PMID:21716595 RGD:6907069 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta ISO
IEP
IDA		 mRNA:increased expression:kidney, liver, spleen (mouse)
protein:increased expression:kidney (rat)		 RGD PMID:22750969 PMID:21677145 PMID:22286667 PMID:22659586 RGD:7175094, RGD:7175314, RGD:7175258, RGD:7175102 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO
IDA		 associated with Sepsis
associated with Asphyxia; rat model treated with human protein		 RGD PMID:16763508 PMID:14610321 PMID:16259926 RGD:6907360, RGD:6907375, RGD:6907369 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il20 interleukin 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18496552 NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188 		JBrowse link
G Il6 interleukin 6 ISO associated with Acute Lung Injury;protein:increased expression:plasma
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:21570986 PMID:18074478 RGD:5128661 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:12243603 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Jak2 Janus kinase 2 treatment IEP associated with Carcinoma, Lewis Lung, human cells in mouse model RGD PMID:31250048 RGD:149735351 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18227104 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042 		JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: therapeutic CTD PMID:513486 PMID:3015452 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine
associated with open cardiac surgeries;protein:increased expression:urine:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20623750 PMID:22005293 PMID:23052191 PMID:27888128 PMID:28885000 More... RGD:7244370, RGD:126781714, RGD:125973912 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001 		JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409 		JBrowse link
G Mb myoglobin ISO protein: increased expression: serum RGD PMID:23497406 PMID:9822635 RGD:7244253, RGD:7244259 NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870 		JBrowse link
G Met met proto-oncogene ISO protein:increased expression:renal parenchyma (rat) RGD PMID:17940345 RGD:2317469 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mfn1 mitofusin 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388 		JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100 		JBrowse link
G Mir122 microRNA 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997 		JBrowse link
G Mir140 microRNA 140 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945 		JBrowse link
G Mir143 microRNA 143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329 		JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309 		JBrowse link
G Mir148a microRNA 148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890 		JBrowse link
G Mir151 microRNA 151 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr15:73,126,664...73,126,731
Ensembl chr15:73,126,664...73,126,731 		JBrowse link
G Mir152 microRNA 152 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32583487 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291 		JBrowse link
G Mir192 microRNA 192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962 		JBrowse link
G Mir215 microRNA 215 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 1:185,045,778...185,045,889
Ensembl chr 1:185,045,778...185,045,889 		JBrowse link
G Mir23a microRNA 23a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mir25 microRNA 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 5:138,163,583...138,163,666
Ensembl chr 5:138,163,583...138,163,666 		JBrowse link
G Mir26a-1 microRNA 26a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953 		JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420 		JBrowse link
G Mir30d microRNA 30d ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr15:68,213,057...68,213,138
Ensembl chr15:68,213,057...68,213,138 		JBrowse link
G Mir335 microRNA 335 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36052886 NCBI chr 6:30,741,298...30,741,395
Ensembl chr 6:30,741,298...30,741,395 		JBrowse link
G Mir423 microRNA 423 disease_progression ISO miRNA:increased expression:serum, urine RGD PMID:32984995 RGD:158014895 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998 		JBrowse link
G Mir486 microRNA 486 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:30682439 PMID:35279909 NCBI chr 8:23,632,571...23,632,698
Ensembl chr 8:23,632,571...23,632,698 		JBrowse link
G Mir494 microRNA 494 ISO RNA:increased expression:urine RGD PMID:23160513 RGD:155883172 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888 		JBrowse link
G Mirlet7i microRNA let7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr10:122,821,545...122,821,629
Ensembl chr10:122,821,545...122,821,629 		JBrowse link
G Mpo myeloperoxidase ISO DNA:haplotye: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20623750 PMID:22739978 PMID:19793022 RGD:6909168, RGD:6909185 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17387702 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:23022334 RGD:7245507 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Muc20 mucin 20 IEP RGD PMID:14565953 RGD:7364790 NCBI chr16:32,597,793...32,617,805
Ensembl chr16:32,597,793...32,617,805 		JBrowse link
G Mug1 murinoglobulin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 6:121,815,455...121,866,016
Ensembl chr 6:121,815,500...121,866,016 		JBrowse link
G Myc myelocytomatosis oncogene susceptibility IEP protein:decreased phosphorylation:kidney (mouse) RGD PMID:23228991 RGD:7207407 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22160772 RGD:13801199 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879 		JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24958931 PMID:24291173 RGD:10412697 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:14531809 RGD:13825139 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:9810145 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO CTD Direct Evidence: marker/mechanism
in females;mRNA:increased expression:cortex of kidney (rat)		 CTD
RGD		 PMID:9788586 PMID:28947737 RGD:13450947 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nppa natriuretic peptide type A ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:1825077 PMID:2948068 PMID:19298916 PMID:22209992 RGD:7247715 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nppb natriuretic peptide type B ISO associated with lung diseases;protein:increased expression:serum:
mRNA:increased expression:kidney
associated with Myocardial Infarction;protein:increased expression:serum:
associated with Pneumonia;protein:increased expression:serum:		 RGD PMID:23837838 PMID:22209992 PMID:23192919 PMID:23415693 RGD:7247620, RGD:7247715, RGD:7247624, RGD:7247622 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26723870 PMID:28230744 RGD:13440091 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Ocln occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19766176 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226 		JBrowse link
G Orm1 orosomucoid 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IMP RGD PMID:21884784 RGD:5510015 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:altered localization RGD PMID:12089381 RGD:7175293 NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685 		JBrowse link
G Plat plasminogen activator, tissue ISO protein:increased expression:plasma (human) RGD PMID:9767551 RGD:11541071 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: therapeutic CTD PMID:17216604 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:20623750 PMID:24011919 PMID:24433871 PMID:17494862 RGD:8553020 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IEP
IMP		 associated with Endotoxemia; mRNA:decreased expression:kidney (mouse) RGD PMID:21881206 PMID:21881206 RGD:7242026, RGD:7242026 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Proc protein C treatment ISO RGD PMID:19092124 RGD:11250410 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Procr protein C receptor, endothelial treatment ISO associated with Sepsis RGD PMID:23807243 RGD:10755583 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391 		JBrowse link
G Ptafr platelet-activating factor receptor treatment ISO associated with Endotoxemia RGD PMID:2538527 RGD:10043182 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21893983 RGD:5508181 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21745194 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO associated with Sepsis;protein:increased phosphorylation:kidney RGD PMID:19428114 RGD:8547990 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Ren1 renin 1 structural exacerbates ISO Associated with toxic shock syndrome;protein:increased expression:blood plasma (human) RGD PMID:30407370 RGD:125097506 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 ISO associated with LPS induced endotoxemia RGD PMID:18824919 RGD:2313129 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO associated with heart failure; protein:decreased activity:plasma: RGD PMID:26108065 RGD:11354006 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Sirt1 sirtuin 1 severity ISO protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21416250 PMID:21416250 RGD:10047111 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 treatment ISO RGD PMID:22414646 RGD:7243179 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14655203 NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 treatment
susceptibility		 ISO DNA:SNP: :808G>T (rs316019) human
mRNA:decreased expression:kidney		 RGD PMID:22414646 PMID:19625999 PMID:18612803 RGD:7243179, RGD:7243884, RGD:7243880 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 disease_progression IEP associated with Sepsis; protein:decreased expression:renal proximal tubule (mouse) RGD PMID:19729856 RGD:7242943 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405 		JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Spp1 secreted phosphoprotein 1 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11274264 PMID:20623750 PMID:22863853 RGD:6903264 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Tbx1 T-box 1 ISO mRNA:increased expression:kidney (rat) RGD PMID:24817956 RGD:155882498 NCBI chr16:18,399,729...18,409,412
Ensembl chr16:18,399,729...18,409,421 		JBrowse link
G Tff3 trefoil factor 3, intestinal ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620 		JBrowse link
G Tgfa transforming growth factor alpha ISO mRNA:increased expression:kidney RGD PMID:11340354 RGD:10395241 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10469268 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Thbd thrombomodulin treatment ISO RGD PMID:19176699 PMID:17804460 RGD:5684994, RGD:5685010 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Tlr2 toll-like receptor 2 IMP
ISO		 associated with Sepsis
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29286200 PMID:22655058 RGD:7207898 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IMP
ISO
IEP		 associated with Sepsis
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29286200 PMID:22655058 PMID:16638912 PMID:22266601 RGD:7207898, RGD:7241084, RGD:6892690 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr9 toll-like receptor 9 IMP associated with Sepsis RGD PMID:23548820 RGD:7245966 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnf tumor necrosis factor susceptibility IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16595132 PMID:18460982 PMID:20623750 PMID:21150875 RGD:7245548 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a susceptibility ISO
IMP		 associated with Acute Lung Injury
associated with Endotoxemia
associated with Shock, Septic;protein:increased expression:serum		 RGD PMID:18074478 PMID:21150875 PMID:12023385 PMID:12500222 RGD:5128661, RGD:7245548, RGD:7245535, RGD:7245534 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO
IMP		 associated with Acute Lung Injury
associated with Shock, Septic;protein:increased expression:serum		 RGD PMID:18074478 PMID:12500222 PMID:12865254 RGD:5128661, RGD:7245534, RGD:7245532 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Trf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
G Trp53 transformation related protein 53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20603111 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3864191 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Uox urate oxidase ISO CTD Direct Evidence: therapeutic CTD PMID:16313266 NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060 		JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:15146030 RGD:2306847 NCBI chr11:121,051,097...121,052,799
Ensembl chr11:121,051,097...121,052,799 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20943766 PMID:22808199 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 ISO RGD PMID:12707392 RGD:727218 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO
IDA		 associated with Reperfusion Injury RGD PMID:22571266 PMID:18539378 PMID:19628223 RGD:7247641, RGD:7247656, RGD:7247650 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Zfp644 zinc finger protein 644 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36052886 NCBI chr 5:106,764,605...106,844,696
Ensembl chr 5:106,764,605...106,845,153 		JBrowse link
acute kidney tubular necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak4 adenylate kinase 4 ISO protein:decreased expression:kidney (rat) RGD PMID:21152904 RGD:5134352 NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO associated with Kidney Reperfusion Injury;protein:increased expression:kidney RGD PMID:16284088 RGD:1601494 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457 		JBrowse link
G Ciita class II transactivator IEP mRNA:increased expression:kidney RGD PMID:9422398 RGD:7242901 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Fabp1 fatty acid binding protein 1, liver ISO CTD Direct Evidence: therapeutic CTD PMID:18368030 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007 		JBrowse link
G Gsr glutathione reductase IMP
ISO		 protein:decreased activity:renal cortex: RGD PMID:17078987 PMID:12885594 RGD:7257555, RGD:7257573 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:kidney tubule, urine: RGD PMID:12081583 RGD:7245970 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Nog noggin ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:4358912 PMID:6254450 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834340 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO CTD Direct Evidence: therapeutic CTD PMID:19917352 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213 		JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Clu clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Cs citrate synthase treatment ISO RGD PMID:20005400 RGD:243048470 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,586 		JBrowse link
G Pdgfa platelet derived growth factor, alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
Contrast-Induced Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp12 caspase 12 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO associated with coronary disease; RGD PMID:23102387 RGD:6909166 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney medulla RGD PMID:18385664 RGD:7243946 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:23335628 RGD:7245471 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hspa5 heat shock protein 5 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Il1b interleukin 1 beta ISO associated with Diabetes Mellitus, Experimental RGD PMID:22094062 RGD:7175334 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine:
associated with Diabetes Mellitus, Experimental; protein:increased expression:urine		 RGD PMID:23335628 PMID:23085980 RGD:7245471, RGD:7245484 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mir188 microRNA 188 ISO RNA:increased expression:plasma
RNA:increased expression:plasma, kidney		 RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr  X:7,114,228...7,114,295
Ensembl chr  X:7,114,228...7,114,295 		JBrowse link
G Mir30a microRNA 30a ISO RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420 		JBrowse link
G Mir30e microRNA 30e ISO RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894 		JBrowse link
G Mpo myeloperoxidase ISO RGD PMID:20722568 RGD:6909183 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Nppa natriuretic peptide type A ISO RGD PMID:19298916 RGD:7247719 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nppb natriuretic peptide type B ISO associated with Heart Failure RGD PMID:20438292 RGD:7248591 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
hepatorenal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7967349 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21253390 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IDA RGD PMID:15531919 RGD:1581228 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA, protein:increased expression:kidney RGD PMID:18093430 RGD:4144102 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:plasma RGD PMID:18093430 RGD:4144102 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO RGD PMID:21680852 RGD:6893484 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 ISO mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Acta1 actin alpha 1, skeletal muscle ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490 		JBrowse link
G Acvr2b activin receptor IIB treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO RGD PMID:22015440 RGD:13703100 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adam2 a disintegrin and metallopeptidase domain 2 ISO RGD PMID:11967014 RGD:10047130 NCBI chr14:66,264,778...66,315,300
Ensembl chr14:66,264,778...66,315,182 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO RGD PMID:18272597 RGD:9684850 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin treatment ISO protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 IMP RGD PMID:31089212 RGD:27226686 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial IMP RGD PMID:22022451 RGD:7241603 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:20953576 RGD:7421585 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:26362957 RGD:13703110 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Atm ataxia telangiectasia mutated ISO protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:18221257 PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 IMP RGD PMID:18725957 RGD:7241559 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687 		JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO RGD PMID:26412257 RGD:11561958 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:19691975 RGD:7411689 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha ISO RGD PMID:19194162 RGD:7204479 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17596683 RGD:5684536 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment IDA RGD PMID:22160777 RGD:7247742 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment
ameliorates		 IEP
ISO		 mRNA, protein:increased expression:kidney, lung, serum RGD PMID:20396927 PMID:18650485 PMID:24920753 RGD:4891433, RGD:11526113, RGD:329845564 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates IMP RGD PMID:24920753 RGD:329845564 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Cd14 CD14 antigen IEP mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen treatment ISO RGD PMID:25993320 RGD:11251055 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cfb complement factor B IMP RGD PMID:16467447 PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Cfh complement component factor h treatment ISO protein:decreased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Ciita class II transactivator IEP RGD PMID:14569092 RGD:7242896 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr  X:101,290,984...101,295,787
Ensembl chr  X:101,290,987...101,295,787 		JBrowse link
G Col1a1 collagen, type I, alpha 1 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col3a1 collagen, type III, alpha 1 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IMP
ISO		 mRNA:increased expression:kidney RGD PMID:23143303 PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:23143303 RGD:7257565 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP
ISO		 RGD PMID:22189844 PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:20038794 RGD:7257679 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment ISO RGD PMID:23552495 RGD:7244372 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Daxx Fas death domain-associated protein IEP
ISO		 protein:increased expression:kidney: RGD PMID:18480747 PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Ddr1 discoidin domain receptor family, member 1 IEP protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513 		JBrowse link
G Dhfr dihydrofolate reductase treatment ISO mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Drd3 dopamine receptor D3 treatment ISO RGD PMID:25989500 RGD:13506961 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295 		JBrowse link
G Eed embryonic ectoderm development IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 7:89,603,862...89,630,184
Ensembl chr 7:89,603,862...89,630,191 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646 		JBrowse link
G Elane elastase, neutrophil expressed treatment ISO RGD PMID:16980042 RGD:10450580 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Eng endoglin ISO
IMP		 mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653 PMID:16751653 RGD:7248779, RGD:7248779 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Ep300 E1A binding protein p300 ISO protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832 PMID:25581532 RGD:10401077, RGD:11041698 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G F3 coagulation factor III ISO protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I treatment ISO RGD PMID:22402584 RGD:9685699 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fgb fibrinogen beta chain treatment ISO mRNA, protein:increased expression:kidney RGD PMID:21685370 PMID:21685370 RGD:7175292, RGD:7175292 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates
ameliorates		 IEP
IMP
ISO		 protein:increased phosphorylation:kidney (mouse) RGD PMID:20591940 PMID:32523960 PMID:29344510 PMID:22688984 RGD:155663667, RGD:155782882, RGD:155782904, RGD:155882537 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Fgg fibrinogen gamma chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:11352844 RGD:7205629 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fos FBJ osteosarcoma oncogene IEP RGD PMID:19095962 RGD:7242184 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:kidney: RGD PMID:20332418 PMID:20332418 RGD:9685723, RGD:9685723 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,130 		JBrowse link
G Glo1 glyoxalase 1 ISO RGD PMID:19211689 PMID:19211689 RGD:7242566, RGD:7242566 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:decreased expression:kidney
mRNA:decreased expression:kidney		 RGD PMID:37033969 PMID:22442209 RGD:401827821, RGD:401827906 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gsr glutathione reductase treatment ISO RGD PMID:24630969 RGD:10401866 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:29137244 RGD:158014894 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 ISO protein:decreased expression:kidney RGD PMID:37033969 RGD:401827821 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G H2ax H2A.X variant histone treatment ISO RGD PMID:23726287 RGD:8693706 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Has1 hyaluronan synthase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467 		JBrowse link
G Has2 hyaluronan synthase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
IEP		 protein:increased expression:urine: RGD PMID:23552495 PMID:23085062 PMID:23019274 RGD:7244372, RGD:7245489, RGD:7245495 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment
severity		 ISO RGD PMID:17519789 PMID:22432008 RGD:1626334, RGD:9068883 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:21291499 RGD:10755580 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hsf1 heat shock factor 1 ISO protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hspa8 heat shock protein 8 ISO RGD PMID:7569112 RGD:7242788 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hyal1 hyaluronoglucosaminidase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chr 9:107,454,149...107,458,898
Ensembl chr 9:107,454,126...107,458,909 		JBrowse link
G Hyal2 hyaluronoglucosaminidase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chr 9:107,445,096...107,449,975
Ensembl chr 9:107,445,144...107,449,978 		JBrowse link
G Ifng interferon gamma treatment IEP RGD PMID:28355607 RGD:14975115 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta treatment ISO RGD PMID:19546526 RGD:7495779 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Il10 interleukin 10 treatment ISO
IEP		 RGD PMID:24079335 PMID:28664613 RGD:7364864, RGD:14975137 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12b interleukin 12b ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:22089199 RGD:8655971 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1b interleukin 1 beta ameliorates ISO
IEP		 RGD PMID:20030532 PMID:24920753 RGD:7175501, RGD:329845564 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO
IMP		 rat model treated with human protein
mouse model treated with human protein		 RGD PMID:18363573 PMID:16849996 PMID:9555664 RGD:6907101, RGD:6907359, RGD:6909149 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Inhbb inhibin beta-B ISO protein:increased expression:serum (rat) RGD PMID:27732750 RGD:329322881 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978 		JBrowse link
G Itgb2 integrin beta 2 ISO Associated with renal transplant patients RGD PMID:20504838 PMID:11007822 RGD:6907049, RGD:6907073 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 ISO protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188 		JBrowse link
G Kl klotho treatment ISO
IMP		 mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278 PMID:16204278 RGD:10403064, RGD:10403064 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282 		JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A IEP protein:increased expression:kidney (mouse) RGD PMID:31570196 RGD:155888490 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594 		JBrowse link
G Lcn2 lipocalin 2 ISO
IEP		 protein:increased expression:urine:
mRNA,protein:increased expression:kidney:
mRNA,protein:increased expression:kidney,urine		 RGD PMID:23364806 PMID:23085062 PMID:20181666 PMID:27800610 RGD:7245469, RGD:7245489, RGD:126779563, RGD:126790572 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lep leptin resistance ISO RGD PMID:22969992 RGD:6909133 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP
ISO		 RGD PMID:20075199 PMID:26412257 RGD:11561916, RGD:11561958 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:23952292 RGD:10412647 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Mc1r melanocortin 1 receptor ISO protein:decreased expression:kidney outer medulla RGD PMID:18790174 RGD:5687322 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483 		JBrowse link
G Mir146 microRNA 146 treatment ISO RGD PMID:27760486 RGD:155882556 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir320 microRNA 320 treatment ISO RGD PMID:31089916 PMID:27760486 RGD:155882543, RGD:155882556 NCBI chr14:70,680,950...70,681,031
Ensembl chr14:70,680,950...70,681,031 		JBrowse link
G Mir381 microRNA 381 ISO RNA:decreased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr12:109,693,256...109,693,330
Ensembl chr12:109,693,256...109,693,330 		JBrowse link
G Mir423 microRNA 423 treatment ISO RGD PMID:29137244 RGD:158014894 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998 		JBrowse link
G Mir494 microRNA 494 ameliorates IMP RGD PMID:23160513 RGD:155883172 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mpo myeloperoxidase ISO
IMP		 protein:increased activity:kidney RGD PMID:22950848 PMID:18055546 RGD:6909167, RGD:7174699 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Muc1 mucin 1, transmembrane treatment ISO RGD PMID:22019164 RGD:7245959 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Myc myelocytomatosis oncogene ISO mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO
IEP		 RGD PMID:24096033 PMID:22160772 RGD:13801197, RGD:13801199 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879 		JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:31089916 RGD:155882543 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible treatment ISO RGD PMID:18408363 RGD:11040540 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:29291552 PMID:18408363 RGD:13504682, RGD:11040540 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nox1 NADPH oxidase 1 treatment ISO RGD PMID:34244746 RGD:329955363 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705 		JBrowse link
G Nppa natriuretic peptide type A ISO RGD PMID:20471588 RGD:7247717 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:21545725 RGD:11035217 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 severity IEP
IMP		 mRNA:increased expression:kidney RGD PMID:22343121 PMID:22343121 RGD:14700869, RGD:14700869 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 ISO RGD PMID:12531391 RGD:2317150 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Pax2 paired box 2 ISO mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chr19:44,735,040...44,826,708
Ensembl chr19:44,744,484...44,826,310 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO mRNA:increased expression:kidney RGD PMID:12819032 PMID:10550325 RGD:1580850, RGD:8554477 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Peg10 paternally expressed 10 IEP mRNA:increased expression:kidney (mouse) RGD PMID:16778176 RGD:401851077 NCBI chr 6:4,747,306...4,760,517
Ensembl chr 6:4,747,306...4,760,517 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha treatment ISO RGD PMID:24918615 RGD:10059636 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase IEP mRNA:increased expression:kidney (mouse) RGD PMID:30413885 RGD:401959745 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO
IEP
IMP		 mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318 PMID:23393318 PMID:23393318 RGD:7327166, RGD:7327166, RGD:7327166 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 severity ISO RGD PMID:26108065 PMID:26108065 RGD:11354006, RGD:11354006 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Shh sonic hedgehog IEP mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Sirt1 sirtuin 1 treatment ISO RGD PMID:22324445 RGD:9495930 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Six2 sine oculis-related homeobox 2 IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr17:85,970,276...85,995,682
Ensembl chr17:85,991,705...85,995,702 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 ISO RGD PMID:21835768 RGD:7243877 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 ISO RGD PMID:21835768 RGD:7243877 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405 		JBrowse link
G Src Rous sarcoma oncogene ISO RGD PMID:12819032 RGD:1580850 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity IMP RGD PMID:12709397 RGD:7244143 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr11:79,883,932...79,924,949
Ensembl chr11:79,883,932...79,924,949 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tlr2 toll-like receptor 2 treatment
severity		 ISO
IDA
IMP
IEP		 RGD PMID:23239000 PMID:23023072 PMID:22750071 PMID:20130923 PMID:11801667 RGD:7207892, RGD:7207894, RGD:7207896, RGD:7240552, RGD:7241087 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO
IMP
IEP		 RGD PMID:23239000 PMID:20130923 PMID:11801667 RGD:7207892, RGD:7240552, RGD:7241087 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor ameliorates ISO
IEP		 protein:increased expression:serum RGD PMID:19925291 PMID:24920753 RGD:2315112, RGD:329845564 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEP mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vwf Von Willebrand factor ISO protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Wt1 WT1 transcription factor IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22995295 PMID:20616412 RGD:7247637, RGD:7247695 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Zfp667 zinc finger protein 667 ameliorates IEP RGD PMID:24920753 RGD:329845564 NCBI chr 7:6,289,187...6,310,882
Ensembl chr 7:6,289,578...6,310,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18300
    disease of anatomical entity 15630
      Urogenital Diseases 4892
        urinary system disease 2500
          kidney disease 2257
            kidney failure 551
              acute kidney failure 323
                Contrast-Induced Nephropathy 16
                Crome Syndrome 0
                Kidney Reperfusion Injury + 162
                acute kidney tubular necrosis 12
                hepatorenal syndrome 5
paths to the root