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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:acute kidney failure
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Accession:DOID:3021 term browser browse the term
Definition:Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Synonyms:exact_synonym: Acute Kidney Failures;   Acute Kidney Injuries;   Acute Kidney Injury;   Acute Kidney Insufficiencies;   Acute Kidney Insufficiency;   Acute Renal Failure;   Acute Renal Failures;   Acute Renal Injuries;   Acute Renal Injury;   Acute Renal Insufficiencies;   Acute Renal Insufficiency
 narrow_synonym: post-operative acute kidney injury;   postoperative acute kidney injury
 primary_id: MESH:D058186;   RDO:0001702
 xref: EFO:0009955
For additional species annotation, visit the Alliance of Genome Resources.

GViewer not supported for the selected species.

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acute kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 treatment ISO associated with endotoxemia; protein:increased expression:kidney
associated with Endotoxemia;
associated with Bacteremia;		 RGD PMID:14747378 PMID:19020966 PMID:19887504 RGD:7175276 RGD:7175281 RGD:7175283 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980 		JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO RGD PMID:21811803 RGD:7243868 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955420:21,071,111...21,078,397
Ensembl chrNW_004955420:21,069,681...21,078,298 		JBrowse link
G Alad aminolevulinate dehydratase ISO protein:decreased activity:kidney (rat) RGD PMID:19484701 RGD:4144146 NCBI chrNW_004955419:14,093,010...14,104,376
Ensembl chrNW_004955419:14,093,010...14,104,545 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2048579 PMID:21259293 PMID:24361871 PMID:28885000 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:19194548 RGD:2317536 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:8963945 PMID:28885000 RGD:6904218 NCBI chrNW_004955419:13,478,904...13,492,329
Ensembl chrNW_004955419:13,478,552...13,492,327 		JBrowse link
G Amn amnion associated transmembrane protein ISO CTD Direct Evidence: therapeutic CTD PMID:20514524 NCBI chrNW_004955538:2,017,476...2,021,890 JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:22101490 RGD:7421583 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Ar androgen receptor ISO RGD PMID:24503548 RGD:11570523 NCBI chrNW_004955475:7,013,960...7,192,473
Ensembl chrNW_004955475:7,013,960...7,186,069 		JBrowse link
G Arg1 arginase 1 ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Arg2 arginase 2 ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25666834 NCBI chrNW_004955458:4,188,167...4,195,575
Ensembl chrNW_004955458:4,186,461...4,195,494 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:17347933 RGD:2300348 NCBI chrNW_004955458:10,245,325...10,253,209
Ensembl chrNW_004955458:10,245,111...10,253,209 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO RGD PMID:23849457 RGD:153350150 NCBI chrNW_004955573:902,153...910,481
Ensembl chrNW_004955573:899,798...912,272 		JBrowse link
G B2m beta-2-microglobulin ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:2689182 PMID:19536607 PMID:22005293 PMID:28885000 RGD:6482685 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO RGD PMID:20037173 RGD:10053672 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:20037173 PMID:20623750 RGD:10053672 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244 		JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Bcl2l1 BCL2 like 1 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chrNW_004955422:29,254,440...29,307,104
Ensembl chrNW_004955422:29,254,216...29,308,174 		JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24975837 NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172 		JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G Capn1 calpain 1 treatment ISO associated with Rhabdomyolysis; RGD PMID:24158126 RGD:13792553 NCBI chrNW_004955422:20,006,448...20,026,984
Ensembl chrNW_004955422:20,004,426...20,025,708 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:serum (mouse) RGD PMID:19508392 RGD:4889990 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chrNW_004955424:12,379,222...12,402,161 JBrowse link
G Cd44 CD44 molecule (IN blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:kidney RGD PMID:16557226 RGD:2293624 NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542 		JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:urine		 CTD
RGD		 PMID:20118187 PMID:20623750 PMID:22005293 PMID:22581811 PMID:23052191 More... RGD:7245501 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955448:470,063...522,909
Ensembl chrNW_004955448:473,179...523,100 		JBrowse link
G Csf1 colony stimulating factor 1 ISO RGD PMID:23143303 RGD:7257565 NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751 		JBrowse link
G Cst3 cystatin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 PMID:28885000 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO Protein:increased expression:renal tubule epithelium RGD PMID:15476864 RGD:1599736 NCBI chrNW_004955458:5,232,979...5,238,513
Ensembl chrNW_004955458:5,232,979...5,238,513 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 ameliorates ISO RGD PMID:19828677 RGD:155663373 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:10073607 PMID:11043448 RGD:7244180 RGD:7244185 NCBI chrNW_004955452:1,653,783...1,704,619
Ensembl chrNW_004955452:1,651,316...1,751,489 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:kidney (mouse)		 CTD
RGD		 PMID:9788586 PMID:19967049 RGD:4144852 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Egf epidermal growth factor ISO mRNA:decreased expression:kidney RGD PMID:11340354 PMID:20482449 RGD:10395241 RGD:6906908 NCBI chrNW_004955496:325,954...401,430
Ensembl chrNW_004955496:328,075...401,569 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: therapeutic
mRNA:increased expression:kidney		 CTD
RGD		 PMID:11340354 PMID:14638913 RGD:10395241 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Egln1 egl-9 family hypoxia inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chrNW_004955492:7,407,800...7,454,851
Ensembl chrNW_004955492:7,407,800...7,454,842 		JBrowse link
G Egln3 egl-9 family hypoxia inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chrNW_004955409:26,939,933...26,967,156
Ensembl chrNW_004955409:26,939,933...26,967,156 		JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO RGD PMID:16762988 RGD:10395386 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:26165641 NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572 		JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21847101 PMID:22209169 PMID:22235348 PMID:24561306 RGD:10400913 RGD:11041660 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355 		JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:renal tubule (rat) RGD PMID:21374789 RGD:8663469 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA:increased expression:kidney (rat) RGD PMID:15805072 RGD:9685024 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fis1 fission, mitochondrial 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623 		JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:kidney RGD PMID:11768240 PMID:12884040 RGD:7205684 RGD:729934 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975 		JBrowse link
G Fstl1 follistatin like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20861081 NCBI chrNW_004955427:19,952,823...20,003,832
Ensembl chrNW_004955427:19,952,853...20,004,241 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:602954 PMID:734759 PMID:4794122 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083 		JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19564549 NCBI chrNW_004955404:276,397...303,864
Ensembl chrNW_004955404:275,946...304,809 		JBrowse link
G Gatm glycine amidinotransferase ISO protein:decreased activity:kidney (rat) RGD PMID:2752493 RGD:1599823 NCBI chrNW_004955409:8,068,524...8,084,603
Ensembl chrNW_004955409:8,068,476...8,084,603 		JBrowse link
G Gc GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:cortex of kidney,renal medulla:
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:20030531 RGD:9685736 NCBI chrNW_004955442:15,280,753...15,283,405
Ensembl chrNW_004955442:15,281,419...15,283,266 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:19625378 RGD:7242430 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO protein:decreased activity:kidney (rat) RGD PMID:23924727 RGD:13506245 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113 		JBrowse link
G Gpnmb glycoprotein nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chrNW_004955410:25,554,279...25,583,368
Ensembl chrNW_004955410:25,553,973...25,582,500 		JBrowse link
G Gpt glutamic--pyruvic transaminase treatment ISO RGD PMID:22209169 RGD:10400913 NCBI chrNW_004955454:3,127,997...3,132,459
Ensembl chrNW_004955454:3,127,997...3,132,459 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:decreased expression:kidney RGD PMID:36583727 RGD:401827125 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032 		JBrowse link
G Gpx4 glutathione peroxidase 4 treatment ISO RGD PMID:29548851 RGD:401827911 NCBI chrNW_004955495:6,767,969...6,772,256
Ensembl chrNW_004955495:6,767,975...6,772,178 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22785175 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137 		JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:decreased activity:kidney:
glycerol-induced		 RGD PMID:1870354 PMID:22286819 RGD:7257559 RGD:7257585 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20623750 PMID:20798258 RGD:6903954 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine
associated with Pyelonephritis;protein:increased expression:urine:
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20118187 PMID:21259293 PMID:21835770 PMID:22005293 PMID:23019274 More... RGD:7244370 RGD:7245472 RGD:7245495 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Hbegf heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:kidney		 CTD
RGD		 PMID:7635938 PMID:11340354 RGD:10395241 NCBI chrNW_004955418:259,860...321,340
Ensembl chrNW_004955418:309,096...321,387 		JBrowse link
G Hdac2 histone deacetylase 2 treatment ISO associated with sepsis; RGD PMID:22933299 RGD:9590257 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707 		JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:21416250 RGD:10047111 NCBI chrNW_004955415:12,138,520...12,154,234
Ensembl chrNW_004955415:12,138,870...12,154,234 		JBrowse link
G Hdac5 histone deacetylase 5 treatment ISO associated with sepsis; RGD PMID:21416250 PMID:22933299 RGD:10047111 RGD:9590257 NCBI chrNW_004955451:17,223,217...17,246,451
Ensembl chrNW_004955451:17,223,287...17,244,051 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO protein:increased expression:kidney tubule (rat)
mRNA:increased expression:kidney collecting duct (rat)		 RGD PMID:24325066 PMID:24397211 RGD:9685383 RGD:9685389 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447 		JBrowse link
G Hexb hexosaminidase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 NCBI chrNW_004955425:25,942,341...25,961,312
Ensembl chrNW_004955425:25,942,278...25,961,312 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO mRNA:increased expression:renal cortex (rat) RGD PMID:15673301 PMID:16762988 PMID:18593636 RGD:10395376 RGD:10395386 RGD:9068894 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36052886 NCBI chrNW_004955435:17,201,866...17,257,371
Ensembl chrNW_004955435:17,172,651...17,257,371 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO associated with Sepsis RGD PMID:16557230 RGD:5508471 NCBI chrNW_004955425:25,362,165...25,380,611
Ensembl chrNW_004955425:25,359,884...25,380,745 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: therapeutic
associated with Sepsis		 CTD
RGD		 PMID:21048024 PMID:23807243 RGD:10755583 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955414:22,158,654...22,169,133
Ensembl chrNW_004955414:22,156,819...22,169,631 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO protein:increased expression:kidney, lysosome (rat) RGD PMID:14966137 RGD:7242786 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:22659586 RGD:7175102 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755 		JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152 		JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO mRNA: decreased expression: kidney: both cortex and medulla RGD PMID:9767523 RGD:7242908 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666 		JBrowse link
G Igfbp1 insulin like growth factor binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chrNW_004955456:6,810,461...6,814,944
Ensembl chrNW_004955456:6,810,056...6,815,685 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18460982 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:11342578 RGD:6893450 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:21716595 RGD:6907069 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466 		JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:kidney, liver, spleen (mouse)
protein:increased expression:kidney (rat)		 RGD PMID:21677145 PMID:22286667 PMID:22659586 PMID:22750969 RGD:7175094 RGD:7175102 RGD:7175258 RGD:7175314 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO associated with Sepsis
associated with Asphyxia; rat model treated with human protein		 RGD PMID:14610321 PMID:16259926 PMID:16763508 RGD:6907360 RGD:6907369 RGD:6907375 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471 		JBrowse link
G Il20 interleukin 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18496552 NCBI chrNW_004955406:42,398,510...42,401,561
Ensembl chrNW_004955406:42,398,782...42,401,490 		JBrowse link
G Il6 interleukin 6 ISO associated with Acute Lung Injury;protein:increased expression:plasma
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:18074478 PMID:21570986 RGD:5128661 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ins insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12243603 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with Carcinoma, Lewis Lung, human cells in mouse model RGD PMID:31250048 RGD:149735351 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208 		JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18227104 NCBI chrNW_004955559:457,030...461,086
Ensembl chrNW_004955559:456,932...465,704 		JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: therapeutic CTD PMID:513486 PMID:3015452 NCBI chrNW_004955420:20,989,197...21,016,084 JBrowse link
G Lgals3 galectin 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G LOC102010322 cytochrome P450 1A2 treatment ISO RGD PMID:18495746 PMID:23981375 RGD:7257727 RGD:7257735 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942 		JBrowse link
G LOC102010850 cytochrome P450 1A1 treatment ISO RGD PMID:18495746 PMID:19890363 RGD:7257732 RGD:7257735 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488 		JBrowse link
G LOC102011841 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO RGD PMID:6223803 RGD:2307326 NCBI chrNW_004955458:5,472,404...5,477,001
Ensembl chrNW_004955458:5,472,404...5,477,001 		JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G LOC102021956 alpha-2-macroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chrNW_004955413:6,019,457...6,062,366
Ensembl chrNW_004955413:6,019,082...6,062,529 		JBrowse link
G LOC102026028 cytochrome P450 2E1 treatment ISO RGD PMID:24412858 PMID:24717297 RGD:14700914 RGD:14700920 NCBI chrNW_004955507:6,293,162...6,303,255
Ensembl chrNW_004955507:6,289,576...6,304,193 		JBrowse link
G LOC102027549 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910 		JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chrNW_004955495:4,402,670...4,405,666
Ensembl chrNW_004955495:4,402,746...4,406,943 		JBrowse link
G Lrp2 LDL receptor related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chrNW_004955449:5,155,109...5,314,886
Ensembl chrNW_004955449:5,160,946...5,314,948 		JBrowse link
G Mb myoglobin ISO protein: increased expression: serum RGD PMID:9822635 PMID:23497406 RGD:7244253 RGD:7244259 NCBI chrNW_004955405:43,215,404...43,221,606
Ensembl chrNW_004955405:43,215,007...43,222,052 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:renal parenchyma (rat) RGD PMID:17940345 RGD:2317469 NCBI chrNW_004955432:22,440,671...22,519,592
Ensembl chrNW_004955432:22,440,637...22,517,647 		JBrowse link
G Mfn1 mitofusin 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chrNW_004955420:8,541,547...8,596,494
Ensembl chrNW_004955420:8,541,936...8,594,437 		JBrowse link
G Mpo myeloperoxidase ISO DNA:haplotye: :
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19793022 PMID:20623750 PMID:22739978 RGD:6909168 RGD:6909185 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17387702 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:23022334 RGD:7245507 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694 		JBrowse link
G Muc20 mucin 20, cell surface associated ISO RGD PMID:14565953 RGD:7364790 NCBI chrNW_004955420:12,212,666...12,234,213 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor susceptibility ISO protein:decreased phosphorylation:kidney (mouse) RGD PMID:23228991 RGD:7207407 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22160772 RGD:13801199 NCBI chrNW_004955485:9,607,781...9,613,123
Ensembl chrNW_004955485:9,607,781...9,613,151 		JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chrNW_004955545:2,748,132...2,756,595
Ensembl chrNW_004955545:2,748,078...2,756,301 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24291173 PMID:24958931 RGD:10412697 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chrNW_004955496:5,842,734...5,950,995
Ensembl chrNW_004955496:5,842,600...5,927,885 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:14531809 RGD:13825139 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9810145 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism
in females;mRNA:increased expression:cortex of kidney (rat)		 CTD
RGD		 PMID:9788586 PMID:28947737 RGD:13450947 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814 		JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:kidney		 CTD
RGD		 PMID:1825077 PMID:2948068 PMID:19298916 PMID:22209992 RGD:7247715 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003 		JBrowse link
G Nppb natriuretic peptide B ISO associated with lung diseases;protein:increased expression:serum:
associated with Myocardial Infarction;protein:increased expression:serum:
associated with Pneumonia;protein:increased expression:serum:
mRNA:increased expression:kidney		 RGD PMID:22209992 PMID:23192919 PMID:23415693 PMID:23837838 RGD:7247620 RGD:7247622 RGD:7247624 RGD:7247715 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26723870 PMID:28230744 RGD:13440091 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604 		JBrowse link
G Ocln occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19766176 NCBI chrNW_004955575:163,646...210,379 JBrowse link
G Orm1 orosomucoid 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955419:13,262,119...13,264,986 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:21884784 RGD:5510015 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:altered localization RGD PMID:12089381 RGD:7175293 NCBI chrNW_004955474:1,831,221...1,868,170
Ensembl chrNW_004955474:1,833,701...1,868,817 		JBrowse link
G Plat plasminogen activator, tissue type ISO protein:increased expression:plasma (human) RGD PMID:9767551 RGD:11541071 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394 		JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955439:20,317,814...20,366,724
Ensembl chrNW_004955439:20,317,552...20,366,475 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: therapeutic CTD PMID:17216604 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:17494862 PMID:20623750 PMID:24011919 PMID:24433871 RGD:8553020 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO associated with Endotoxemia; mRNA:decreased expression:kidney (mouse) RGD PMID:21881206 RGD:7242026 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19092124 RGD:11250410 NCBI chrNW_004955459:3,097,229...3,105,566
Ensembl chrNW_004955459:3,094,120...3,104,135 		JBrowse link
G Procr protein C receptor treatment ISO associated with Sepsis RGD PMID:23807243 RGD:10755583 NCBI chrNW_004955422:26,215,757...26,220,396
Ensembl chrNW_004955422:26,216,002...26,220,101 		JBrowse link
G Ptafr platelet activating factor receptor treatment ISO associated with Endotoxemia RGD PMID:2538527 RGD:10043182 NCBI chrNW_004955452:7,309,854...7,345,579
Ensembl chrNW_004955452:7,311,901...7,312,929 		JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21893983 RGD:5508181 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21745194 NCBI chrNW_004955500:6,655,056...6,674,311
Ensembl chrNW_004955500:6,655,056...6,674,311 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO associated with Sepsis;protein:increased phosphorylation:kidney RGD PMID:19428114 RGD:8547990 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576 		JBrowse link
G Ren renin exacerbates ISO Associated with toxic shock syndrome;protein:increased expression:blood plasma (human) RGD PMID:30407370 RGD:125097506 NCBI chrNW_004955406:40,016,624...40,026,286
Ensembl chrNW_004955406:40,016,630...40,026,286 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO associated with LPS induced endotoxemia RGD PMID:18824919 RGD:2313129 NCBI chrNW_004955599:688,414...690,644 JBrowse link
G Serpinc1 serpin family C member 1 ISO associated with heart failure; protein:decreased activity:plasma: RGD PMID:26108065 RGD:11354006 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948 		JBrowse link
G Sirt1 sirtuin 1 severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney (rat)		 CTD
RGD		 PMID:21416250 RGD:10047111 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14655203 NCBI chrNW_004955422:20,555,458...20,561,818
Ensembl chrNW_004955422:20,556,098...20,596,012 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 treatment
susceptibility		 ISO mRNA:decreased expression:kidney
DNA:SNP: :808G>T (rs316019) human		 RGD PMID:18612803 PMID:19625999 PMID:22414646 RGD:7243179 RGD:7243880 RGD:7243884 NCBI chrNW_004955439:20,567,241...20,608,281
Ensembl chrNW_004955439:20,567,212...20,609,105 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 disease_progression ISO associated with Sepsis; protein:decreased expression:renal proximal tubule (mouse) RGD PMID:19729856 RGD:7242943 NCBI chrNW_004955408:29,626,775...29,640,811
Ensembl chrNW_004955408:29,626,775...29,640,875 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11274264 PMID:20623750 PMID:22863853 RGD:6903264 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016 		JBrowse link
G Tbx1 T-box transcription factor 1 ISO mRNA:increased expression:kidney (rat) RGD PMID:24817956 RGD:155882498 NCBI chrNW_004955442:18,320,674...18,327,062
Ensembl chrNW_004955442:18,319,762...18,325,337 		JBrowse link
G Tff3 trefoil factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chrNW_004955407:39,398,534...39,401,085
Ensembl chrNW_004955407:39,398,074...39,401,248 		JBrowse link
G Tgfa transforming growth factor alpha ISO mRNA:increased expression:kidney RGD PMID:11340354 RGD:10395241 NCBI chrNW_004955424:14,616,390...14,709,723
Ensembl chrNW_004955424:14,616,259...14,710,183 		JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10469268 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chrNW_004955419:26,490,899...26,546,349
Ensembl chrNW_004955419:26,490,899...26,547,017 		JBrowse link
G Thbd thrombomodulin treatment ISO RGD PMID:17804460 PMID:19176699 RGD:5684994 RGD:5685010 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Tlr2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism
associated with Sepsis		 CTD
RGD		 PMID:22655058 PMID:29286200 RGD:7207898 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr4 toll like receptor 4 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Sepsis		 CTD
RGD		 PMID:16638912 PMID:22266601 PMID:22655058 PMID:29286200 RGD:6892690 RGD:7207898 RGD:7241084 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr9 toll like receptor 9 ISO associated with Sepsis RGD PMID:23548820 RGD:7245966 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:16595132 PMID:18460982 PMID:20623750 PMID:21150875 RGD:7245548 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chrNW_004955442:14,320,159...14,322,146
Ensembl chrNW_004955442:14,320,159...14,322,146 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A susceptibility ISO associated with Endotoxemia
associated with Acute Lung Injury
associated with Shock, Septic;protein:increased expression:serum		 RGD PMID:12023385 PMID:12500222 PMID:18074478 PMID:21150875 RGD:5128661 RGD:7245534 RGD:7245535 RGD:7245548 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO associated with Acute Lung Injury
associated with Shock, Septic;protein:increased expression:serum		 RGD PMID:12500222 PMID:12865254 PMID:18074478 RGD:5128661 RGD:7245532 RGD:7245534 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20603111 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004955402:18,921,235...18,927,976
Ensembl chrNW_004955402:18,921,274...18,928,108 		JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:15146030 RGD:2306847 NCBI chrNW_004955506:756,859...761,891 JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20943766 PMID:22808199 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Wnt4 Wnt family member 4 ISO RGD PMID:12707392 RGD:727218 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
G Znf644 zinc finger protein 644 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36052886 NCBI chrNW_004955423:3,251,726...3,346,023
Ensembl chrNW_004955423:3,251,119...3,348,039 		JBrowse link
acute kidney tubular necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak4 adenylate kinase 4 ISO protein:decreased expression:kidney (rat) RGD PMID:21152904 RGD:5134352 NCBI chrNW_004955423:25,395,086...25,402,324
Ensembl chrNW_004955423:25,395,836...25,427,474 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO associated with Kidney Reperfusion Injury;protein:increased expression:kidney RGD PMID:16284088 RGD:1601494 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chrNW_004955424:12,379,222...12,402,161 JBrowse link
G Ciita class II major histocompatibility complex transactivator ISO mRNA:increased expression:kidney RGD PMID:9422398 RGD:7242901 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624 		JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:decreased activity:renal cortex: RGD PMID:12885594 PMID:17078987 RGD:7257555 RGD:7257573 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:kidney tubule, urine: RGD PMID:12081583 RGD:7245970 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Nog noggin ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chrNW_004955451:6,192,368...6,193,766
Ensembl chrNW_004955451:6,193,042...6,193,740 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4358912 PMID:6254450 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834340 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19917352 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chrNW_004955472:7,633,790...7,748,130
Ensembl chrNW_004955472:7,633,721...7,748,386 		JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chrNW_004955472:3,141,473...3,170,959
Ensembl chrNW_004955472:3,141,257...3,170,959 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480 		JBrowse link
G Clu clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
G Cs citrate synthase treatment ISO RGD PMID:20005400 RGD:243048470 NCBI chrNW_004955458:3,881,798...3,913,044
Ensembl chrNW_004955458:3,881,798...3,893,401 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO mRNA:increased expression:kidney: RGD PMID:11889420 PMID:15785371 RGD:10449491 RGD:11080974 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004955447:16,570,652...16,613,410
Ensembl chrNW_004955447:16,569,909...16,612,373 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587 		JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600 RGD:13208601 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142 		JBrowse link
Contrast-Induced Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Ddit3 DNA damage inducible transcript 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chrNW_004955458:5,232,979...5,238,513
Ensembl chrNW_004955458:5,232,979...5,238,513 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney medulla RGD PMID:18385664 RGD:7243946 NCBI chrNW_004955452:1,653,783...1,704,619
Ensembl chrNW_004955452:1,651,316...1,751,489 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:23335628 RGD:7245471 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131 		JBrowse link
G Il1b interleukin 1 beta ISO associated with Diabetes Mellitus, Experimental RGD PMID:22094062 RGD:7175334 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
G Mpo myeloperoxidase ISO RGD PMID:20722568 RGD:6909183 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358 		JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:19298916 RGD:7247719 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003 		JBrowse link
G Nppb natriuretic peptide B ISO associated with Heart Failure RGD PMID:20438292 RGD:7248591 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
hepatorenal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7967349 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21253390 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:15531919 RGD:1581228 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727 		JBrowse link
G Tlr4 toll like receptor 4 ISO mRNA, protein:increased expression:kidney RGD PMID:18093430 RGD:4144102 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:plasma RGD PMID:18093430 RGD:4144102 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 ISO mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495 		JBrowse link
G Acta1 actin alpha 1, skeletal muscle ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955492:8,644,696...8,647,412
Ensembl chrNW_004955492:8,644,146...8,647,523 		JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chrNW_004955427:25,438,652...25,467,360
Ensembl chrNW_004955427:25,438,652...25,467,360 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:22015440 RGD:13703100 NCBI chrNW_004955487:5,180,241...5,218,298
Ensembl chrNW_004955487:5,180,252...5,218,216 		JBrowse link
G Adam2 ADAM metallopeptidase domain 2 ISO RGD PMID:11967014 RGD:10047130 NCBI chrNW_004955403:50,046,262...50,115,004
Ensembl chrNW_004955403:50,046,004...50,117,201 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO RGD PMID:18272597 RGD:9684850 NCBI chrNW_004955407:26,524,487...26,533,038
Ensembl chrNW_004955407:26,524,130...26,533,038 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402 		JBrowse link
G Adm adrenomedullin treatment ISO protein:increased expression:serum: RGD PMID:20538296 RGD:7364948 NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:31089212 RGD:27226686 NCBI chrNW_004955464:12,715,238...12,729,034
Ensembl chrNW_004955464:12,714,717...12,729,662 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO RGD PMID:22022451 RGD:7241603 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899 		JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:20953576 RGD:7421585 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chrNW_004955428:18,873,782...18,907,955
Ensembl chrNW_004955428:18,873,782...18,907,955 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:26362957 RGD:13703110 NCBI chrNW_004955405:34,619,780...34,693,616
Ensembl chrNW_004955405:34,623,267...34,693,677 		JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298 		JBrowse link
G Atm ATM serine/threonine kinase ISO protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:18221257 PMID:29285062 RGD:13792599 RGD:2293026 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:18725957 RGD:7241559 NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691 		JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:26412257 RGD:11561958 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955429:6,548,586...6,553,730
Ensembl chrNW_004955429:6,547,731...6,558,105 		JBrowse link
G Bnip3 BCL2 interacting protein 3 ISO mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chrNW_004955477:9,621,812...9,630,406
Ensembl chrNW_004955477:9,621,812...9,638,099 		JBrowse link
G C3 complement C3 treatment ISO RGD PMID:19691975 RGD:7411689 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17596683 RGD:5684536 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Cd14 CD14 molecule ISO mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:25993320 RGD:11251055 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cfb complement factor B ISO RGD PMID:12538716 PMID:16467447 RGD:7242709 RGD:7242734 NCBI chrNW_004955437:461,235...466,908
Ensembl chrNW_004955437:461,235...470,464 		JBrowse link
G Ciita class II major histocompatibility complex transactivator ISO RGD PMID:14569092 RGD:7242896 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624 		JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955475:11,722,514...11,725,067 JBrowse link
G Col1a1 collagen type I alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955403:9,720,831...9,758,019
Ensembl chrNW_004955403:9,721,114...9,757,887 		JBrowse link
G Csf1 colony stimulating factor 1 ISO mRNA:increased expression:kidney RGD PMID:19196448 PMID:23143303 RGD:7257565 RGD:7257570 NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 ISO RGD PMID:9407517 PMID:22189844 RGD:7204675 RGD:7204727 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109 		JBrowse link
G Daxx death domain associated protein ISO protein:increased expression:kidney: RGD PMID:18480747 RGD:9587836 NCBI chrNW_004955437:1,869,692...1,874,041
Ensembl chrNW_004955437:1,869,572...1,873,050 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chrNW_004955583:820,893...838,515
Ensembl chrNW_004955583:820,931...841,654 		JBrowse link
G Dhfr dihydrofolate reductase treatment ISO mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chrNW_004955418:29,274,170...29,283,028 JBrowse link
G Drd3 dopamine receptor D3 treatment ISO RGD PMID:25989500 RGD:13506961 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Eed embryonic ectoderm development ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955414:6,659,144...6,685,530
Ensembl chrNW_004955414:6,659,055...6,685,530 		JBrowse link
G Egln1 egl-9 family hypoxia inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chrNW_004955492:7,407,800...7,454,851
Ensembl chrNW_004955492:7,407,800...7,454,842 		JBrowse link
G Egln3 egl-9 family hypoxia inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chrNW_004955409:26,939,933...26,967,156
Ensembl chrNW_004955409:26,939,933...26,967,156 		JBrowse link
G Eng endoglin ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653 RGD:7248779 NCBI chrNW_004955419:818,797...853,319
Ensembl chrNW_004955419:818,932...852,694 		JBrowse link
G Ep300 E1A binding protein p300 ISO protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832 PMID:25581532 RGD:10401077 RGD:11041698 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235 		JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chrNW_004955423:254,060...264,448
Ensembl chrNW_004955423:254,189...264,159 		JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain treatment ISO mRNA, protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates
ameliorates		 ISO protein:increased phosphorylation:kidney (mouse) RGD PMID:20591940 PMID:22688984 PMID:29344510 PMID:32523960 RGD:155663667 RGD:155782882 RGD:155782904 RGD:155882537 NCBI chrNW_004955551:2,321,190...2,427,000 JBrowse link
G Fgg fibrinogen gamma chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chrNW_004955471:8,786,910...8,794,947
Ensembl chrNW_004955471:8,786,910...8,795,013 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:11352844 RGD:7205629 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:19095962 RGD:7242184 NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:kidney: RGD PMID:20332418 RGD:9685723 NCBI chrNW_004955442:15,280,753...15,283,405
Ensembl chrNW_004955442:15,281,419...15,283,266 		JBrowse link
G Glo1 glyoxalase I ISO RGD PMID:19211689 RGD:7242566 NCBI chrNW_004955437:4,728,709...4,749,834
Ensembl chrNW_004955437:4,728,709...4,749,834 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:decreased expression:kidney
mRNA:decreased expression:kidney		 RGD PMID:22442209 PMID:37033969 RGD:401827821 RGD:401827906 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032 		JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO RGD PMID:24630969 RGD:10401866 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583 		JBrowse link
G Has1 hyaluronan synthase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chrNW_004955558:826,853...836,809
Ensembl chrNW_004955558:826,853...836,809 		JBrowse link
G Has2 hyaluronan synthase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chrNW_004955540:593,316...609,760
Ensembl chrNW_004955540:593,316...609,865 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:23019274 PMID:23085062 PMID:23552495 RGD:7244372 RGD:7245489 RGD:7245495 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment
severity		 ISO RGD PMID:17519789 PMID:22432008 RGD:1626334 RGD:9068883 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:21291499 RGD:10755580 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:7569112 RGD:7242788 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
G Hyal1 hyaluronidase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chrNW_004955532:2,113,016...2,116,093
Ensembl chrNW_004955532:2,112,771...2,115,952 		JBrowse link
G Hyal2 hyaluronidase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chrNW_004955532:2,120,781...2,125,083
Ensembl chrNW_004955532:2,120,781...2,123,726 		JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:28355607 RGD:14975115 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:19546526 RGD:7495779 NCBI chrNW_004955536:611,965...658,647
Ensembl chrNW_004955536:612,774...658,647 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:24079335 PMID:28664613 RGD:14975137 RGD:7364864 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il12b interleukin 12B ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:22089199 RGD:8655971 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il1b interleukin 1 beta ameliorates ISO RGD PMID:20030532 PMID:24920753 RGD:329845564 RGD:7175501 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO mouse model treated with human protein
rat model treated with human protein		 RGD PMID:9555664 PMID:16849996 PMID:18363573 RGD:6907101 RGD:6907359 RGD:6909149 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471 		JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Inhbb inhibin subunit beta B ISO protein:increased expression:serum (rat) RGD PMID:27732750 RGD:329322881 NCBI chrNW_004955459:9,482,998...9,488,489
Ensembl chrNW_004955459:9,482,873...9,488,489 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO Associated with renal transplant patients RGD PMID:11007822 PMID:20504838 RGD:6907049 RGD:6907073 NCBI chrNW_004955407:41,779,849...41,805,637
Ensembl chrNW_004955407:41,777,777...41,800,201 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 ISO protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717 		JBrowse link
G Kl klotho treatment ISO mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278 RGD:10403064 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO protein:increased expression:kidney (mouse) RGD PMID:31570196 RGD:155888490 NCBI chrNW_004955412:19,586,435...19,670,149
Ensembl chrNW_004955412:19,586,141...19,665,527 		JBrowse link
G Lep leptin resistance ISO RGD PMID:22969992 RGD:6909133 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472 		JBrowse link
G Lgals3 galectin 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G LOC102018844 neutrophil elastase treatment ISO RGD PMID:16980042 RGD:10450580 NCBI chrNW_004955495:6,964,577...6,967,208
Ensembl chrNW_004955495:6,964,667...6,967,106 		JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like treatment ISO RGD PMID:28235038 RGD:14695051 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G LOC102023780 aromatase treatment ISO RGD PMID:23552495 RGD:7244372 NCBI chrNW_004955409:3,198,622...3,313,072
Ensembl chrNW_004955409:3,266,233...3,313,142 		JBrowse link
G LOC102025775 histone H2AX treatment ISO RGD PMID:23726287 RGD:8693706 NCBI chrNW_004955412:20,203,173...20,204,714
Ensembl chrNW_004955412:20,203,772...20,204,203 		JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:20075199 PMID:26412257 RGD:11561916 RGD:11561958 NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:23952292 RGD:10412647 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:kidney RGD PMID:18055546 PMID:22950848 RGD:6909167 RGD:7174699 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358 		JBrowse link
G Muc1 mucin 1, cell surface associated treatment ISO RGD PMID:22019164 RGD:7245959 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22160772 PMID:24096033 RGD:13801197 RGD:13801199 NCBI chrNW_004955485:9,607,781...9,613,123
Ensembl chrNW_004955485:9,607,781...9,613,151 		JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chrNW_004955545:2,748,132...2,756,595
Ensembl chrNW_004955545:2,748,078...2,756,301 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:31089916 RGD:155882543 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944 		JBrowse link
G Nos2 nitric oxide synthase 2 treatment ISO RGD PMID:18408363 RGD:11040540 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO RGD PMID:18408363 PMID:29291552 RGD:11040540 RGD:13504682 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814 		JBrowse link
G Nox1 NADPH oxidase 1 treatment ISO RGD PMID:34244746 RGD:329955363 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618 		JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:20471588 RGD:7247717 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:21545725 RGD:11035217 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4 group A member 1 severity ISO mRNA:increased expression:kidney RGD PMID:22343121 RGD:14700869 NCBI chrNW_004955547:2,404,532...2,426,882
Ensembl chrNW_004955547:2,404,532...2,431,050 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO RGD PMID:12531391 RGD:2317150 NCBI chrNW_004955561:1,277,362...1,282,949
Ensembl chrNW_004955561:1,277,365...1,282,793 		JBrowse link
G Pax2 paired box 2 ISO mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chrNW_004955447:16,570,652...16,613,410
Ensembl chrNW_004955447:16,569,909...16,612,373 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO mRNA:increased expression:kidney RGD PMID:10550325 PMID:12819032 RGD:1580850 RGD:8554477 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587 		JBrowse link
G Peg10 paternally expressed 10 ISO mRNA:increased expression:kidney (mouse) RGD PMID:16778176 RGD:401851077 NCBI chrNW_004955432:11,383,919...11,395,313
Ensembl chrNW_004955432:11,390,847...11,391,929 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chrNW_004955474:1,831,221...1,868,170
Ensembl chrNW_004955474:1,833,701...1,868,817 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO RGD PMID:24918615 RGD:10059636 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO mRNA:increased expression:kidney (mouse) RGD PMID:30413885 RGD:401959745 NCBI chrNW_004955445:8,624,228...8,663,385
Ensembl chrNW_004955445:8,623,430...8,677,658 		JBrowse link
G Rnls renalase, FAD dependent amine oxidase ISO mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318 RGD:7327166 NCBI chrNW_004955425:4,368,620...4,667,947 JBrowse link
G Serpinc1 serpin family C member 1 severity ISO RGD PMID:26108065 RGD:11354006 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948 		JBrowse link
G Serpine1 serpin family E member 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Sirt1 sirtuin 1 treatment ISO RGD PMID:22324445 RGD:9495930 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Six2 SIX homeobox 2 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955441:12,029,530...12,033,214
Ensembl chrNW_004955441:12,029,480...12,033,214 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 ISO RGD PMID:21835768 RGD:7243877 NCBI chrNW_004955439:20,567,241...20,608,281
Ensembl chrNW_004955439:20,567,212...20,609,105 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chrNW_004955408:29,626,775...29,640,811
Ensembl chrNW_004955408:29,626,775...29,640,875 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:12819032 RGD:1580850 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO RGD PMID:12709397 RGD:7244143 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955481:6,867,175...6,917,548
Ensembl chrNW_004955481:6,867,175...6,917,548 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chrNW_004955403:10,925,155...11,004,229
Ensembl chrNW_004955403:10,924,893...11,004,284 		JBrowse link
G Tgfb1 transforming growth factor beta 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tlr2 toll like receptor 2 treatment
severity		 ISO RGD PMID:11801667 PMID:20130923 PMID:22750071 PMID:23023072 PMID:23239000 RGD:7207892 RGD:7207894 RGD:7207896 RGD:7240552 RGD:7241087 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr4 toll like receptor 4 treatment ISO RGD PMID:11801667 PMID:20130923 PMID:23239000 RGD:7207892 RGD:7240552 RGD:7241087 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tnf tumor necrosis factor ameliorates ISO protein:increased expression:serum RGD PMID:19925291 PMID:24920753 RGD:2315112 RGD:329845564 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691 		JBrowse link
G Vwf von Willebrand factor ISO protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chrNW_004955413:3,672,470...3,825,588
Ensembl chrNW_004955413:3,672,470...3,819,571 		JBrowse link
G Wt1 WT1 transcription factor ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chrNW_004955476:10,464,688...10,504,473
Ensembl chrNW_004955476:10,464,616...10,504,473 		JBrowse link
G Znf667 zinc finger protein 667 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chrNW_004955567:395,089...404,130
Ensembl chrNW_004955567:393,977...402,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16063
    disease of anatomical entity 13820
      Urogenital Diseases 4394
        urinary system disease 2228
          kidney disease 2019
            kidney failure 468
              acute kidney failure 263
                Contrast-Induced Nephropathy 10
                Crome Syndrome 0
                Kidney Reperfusion Injury + 142
                acute kidney tubular necrosis 11
                hepatorenal syndrome 5
paths to the root