RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: invasive ductal carcinoma
Accession: DOID:3008
browse the term
Definition: A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated. (DO)
Synonyms: exact_synonym: ductal adenocarcinoma; infiltrating duct carcinoma; infiltrating duct carcinoma of breast; infiltrating duct carcinomas; infiltrating ductal carcinoma of breast; invasive breast ductal carcinoma; invasive ductal breast cancer; invasive ductal carcinoma, NST; invasive ductal carcinoma, not otherwise specified; mammary ductal carcinoma; mammary ductal carcinomas
narrow_synonym: invasive breast ductal and lobular carcinoma
primary_id: MESH:D018270
xref: EFO:0000184 ; EFO:0000186 ; EFO:0000552 ; NCI:C4017 ; NCI:C4194
For additional species annotation, visit the
Alliance of Genome Resources .
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Abcb1a
ATP-binding cassette, sub-family B member 1A
disease_progression
ISO
RGD
PMID:19879256
RGD:2315549
NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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Abcc9
ATP-binding cassette, sub-family C member 9
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 6:142,533,592...142,648,472
Ensembl chr 6:142,533,588...142,648,041
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Adam28
a disintegrin and metallopeptidase domain 28
disease_progression
ISO
DNA:hypermethylation:CpG island
RGD
PMID:19549921
RGD:153298911
NCBI chr14:68,842,447...68,893,338
Ensembl chr14:68,843,476...68,893,291
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Adgrb1
adhesion G protein-coupled receptor B1
disease_progression
ISO
RGD
PMID:25376607
RGD:13831358
NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314
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Ager
advanced glycosylation end product-specific receptor
ISO
protein:increased expression:breast
RGD
PMID:22366088
RGD:8695990
NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
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Akt1
thymoma viral proto-oncogene 1
ISO
DNA:missense mutation:p.E17K (human)
RGD
PMID:18392055
RGD:13209138
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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Alox5
arachidonate 5-lipoxygenase
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
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Amfr
autocrine motility factor receptor
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 8:94,698,216...94,739,301
Ensembl chr 8:94,698,216...94,739,470
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Anxa1
annexin A1
treatment
ISO
RGD
PMID:18776816 PMID:19171478
RGD:7421535 , RGD:7421560
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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Anxa2
annexin A2
treatment
ISO
RGD
PMID:19171478
RGD:7421560
NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
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Ar
androgen receptor
severity
ISO
RGD
PMID:16075292
RGD:1643344
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Areg
amphiregulin
ISO
RGD
PMID:11523048
RGD:2292660
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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Arpc2
actin related protein 2/3 complex, subunit 2
ISO
protein:increased expression:breast (human)
RGD
PMID:21136934
RGD:11049179
NCBI chr 1:74,275,656...74,307,368
Ensembl chr 1:74,275,243...74,307,368
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Atf4
activating transcription factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14604972
NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
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Aurka
aurora kinase A
ISO
protein:altered expression
RGD
PMID:14693746
RGD:1643348
NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
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Bag1
BCL2-associated athanogene 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19066611
NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294
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Brca1
breast cancer 1, early onset
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast
ClinVar
PMID:7493024 PMID:9063749 PMID:10196379 PMID:11179017 PMID:11400546 PMID:11956590 PMID:12698193 PMID:12955716 PMID:14517958 PMID:14555511 PMID:14760071 PMID:15145354 PMID:15235020 PMID:16014699 PMID:16455195 PMID:17341484 PMID:17585057 PMID:17645508 PMID:19661094 PMID:20104584 PMID:20727672 PMID:21232165 PMID:21702907 PMID:21708019 PMID:21965345 PMID:21990134 PMID:22136207 PMID:22703879 PMID:22711857 PMID:22798144 PMID:23192404 PMID:23249957 PMID:23469205 PMID:23479189 PMID:23633455 PMID:24033266 PMID:24728327 PMID:24884479 PMID:25256238 PMID:25741868 PMID:25863477 PMID:26026974 PMID:26295337 PMID:26467025 PMID:28324225 PMID:28492532 PMID:29446198 PMID:30078507 PMID:30702160 PMID:30720863 PMID:31214711 PMID:33471991 PMID:36329109 More...
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
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Brca2
breast cancer 2, early onset
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast
ClinVar
PMID:11062481 PMID:11927503 PMID:14555511 PMID:14973102 PMID:15145354 PMID:15235023 PMID:17767707 PMID:17899372 PMID:18627636 PMID:18779604 PMID:19043619 PMID:19499246 PMID:20135345 PMID:21218378 PMID:22126563 PMID:22476429 PMID:22703879 PMID:24033266 PMID:24323938 PMID:24470074 PMID:24728327 PMID:25741868 PMID:25782689 PMID:25980754 PMID:26221963 PMID:26402875 PMID:26467025 PMID:26530882 PMID:26757417 PMID:27157322 PMID:27257965 PMID:27658390 PMID:27701467 PMID:27907908 PMID:28111427 PMID:28222693 PMID:28277317 PMID:28283652 PMID:28351343 PMID:28419251 PMID:28492532 PMID:28993434 PMID:29192238 PMID:29240602 PMID:29394989 PMID:29681614 PMID:29752822 PMID:29988080 PMID:30287823 PMID:30415210 PMID:30702160 PMID:31825140 PMID:31837001 PMID:31911673 PMID:32444794 PMID:32467295 PMID:33428613 PMID:33471991 PMID:33563768 PMID:36329109 More...
NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
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Brms1
breast cancer metastasis-suppressor 1
disease_progression
ISO
RGD
PMID:15592684
RGD:2289400
NCBI chr19:5,091,391...5,099,940
Ensembl chr19:5,091,382...5,099,945
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Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
PMID:28492532
NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851
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Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
PMID:26467025 PMID:27148582 PMID:28492532
NCBI chr17:25,593,259...25,655,308
Ensembl chr17:25,593,259...25,652,759
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Cav1
caveolin 1, caveolae protein
no_association
ISO
DNA:missense mutation: :p.P132L (human)
RGD
PMID:21909981
RGD:8661779
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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Ccdc180
coiled-coil domain containing 180
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 4:45,890,303...45,950,774
Ensembl chr 4:45,890,303...45,950,774
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Ccdc71l
coiled-coil domain containing 71 like
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr12:32,428,788...32,432,942
Ensembl chr12:32,428,703...32,432,942
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Ccl5
C-C motif chemokine ligand 5
ISO
protein:increased expression:breast, ductal carcinoma (human)
RGD
PMID:18790652
RGD:4891911
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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Ccnd3
cyclin D3
severity
ISO
protein:increased expression:breast
RGD
PMID:11329139
RGD:2316016
NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
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Cd274
CD274 antigen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16611412
NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
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Cd44
CD44 antigen
disease_progression
ISO
protein:increased expression:breast
RGD
PMID:17059779
RGD:2289352
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
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Cdh1
cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8557030 PMID:17660459
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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Cdkn2a
cyclin dependent kinase inhibitor 2A
ISO
DNA:hypermethylation:promoter:breast, serum
RGD
PMID:17383681
RGD:2289677
NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
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Cldn4
claudin 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19142967
NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
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Clu
clusterin
ISO
RGD
PMID:10934144
RGD:8699513
NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
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Cnnm1
cyclin M1
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr19:43,427,508...43,485,649
Ensembl chr19:43,428,875...43,485,649
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Coro6
coronin 6
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr11:77,353,149...77,361,310
Ensembl chr11:77,353,237...77,361,310
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Cpxm2
carboxypeptidase X, M14 family member 2
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 7:131,634,416...131,756,483
Ensembl chr 7:131,634,416...131,756,468
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Creb3
cAMP responsive element binding protein 3
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 4:43,562,658...43,567,061
Ensembl chr 4:43,562,332...43,567,060
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Crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
disease_progression
ISO
protein:increased expression:breast
RGD
PMID:23686806
RGD:7488897
NCBI chr16:17,269,849...17,305,304
Ensembl chr16:17,269,851...17,305,298
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Csnk1e
casein kinase 1, epsilon
ISO
DNA:mutation:CDS:multiple nonsynonymous mutations (human)
RGD
PMID:14871824
RGD:2306813
NCBI chr15:79,302,054...79,339,779
Ensembl chr15:79,302,056...79,339,767
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Dlg1
discs large MAGUK scaffold protein 1
ISO
DNA:mutation:CDS:multiple nonsynonymous mutations (human)
RGD
PMID:14871824
RGD:2306813
NCBI chr16:31,482,261...31,692,174
Ensembl chr16:31,482,261...31,693,947
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Ebag9
estrogen receptor-binding fragment-associated gene 9
ISO
mRNA, protein:increased expression:breast
RGD
PMID:11742495
RGD:2289858
NCBI chr15:44,482,574...44,504,916
Ensembl chr15:44,482,571...44,504,911
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Erbb2
erb-b2 receptor tyrosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28235801
NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
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Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
ISO
RGD
PMID:14532106
RGD:9588325
NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275
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Fgd1
FYVE, RhoGEF and PH domain containing 1
ISO
protein:increased expression:breast (human)
RGD
PMID:19141649
RGD:11554027
NCBI chr X:149,829,141...149,872,682
Ensembl chr X:149,829,146...149,872,517
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Fhit
fragile histidine triad gene
ISO
RGD
PMID:12231533
RGD:2289894
NCBI chr14:11,307,718...12,919,681
Ensembl chr14:11,307,738...12,919,681
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Foxc1
forkhead box C1
disease_progression
ISO
RGD
PMID:21424368
RGD:8662363
NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459
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Fubp1
far upstream element (FUSE) binding protein 1
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463
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Gm7298
predicted gene 7298
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 6:121,711,454...121,761,598
Ensembl chr 6:121,709,891...121,766,043
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Hif1a
hypoxia inducible factor 1, alpha subunit
ISO
protein:altered localization:nucleus
RGD
PMID:16080559
RGD:2306227
NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
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Hoxb7
homeobox B7
ISO
mRNA:increased expression:breast epithelium (human)
RGD
PMID:17018609
RGD:10402178
NCBI chr11:96,176,431...96,180,989
Ensembl chr11:96,177,449...96,180,988
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
severity
ISO
protein:decreased expression:ductal breast carcinoma (human)
RGD
PMID:10682658
RGD:4890946
NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353
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Htra2
HtrA serine peptidase 2
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254
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Il13
interleukin 13
ISO
protein:increased expression:breast
RGD
PMID:22135852
RGD:8549515
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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Il18
interleukin 18
ISO
protein:increased expression:breast
RGD
PMID:21263407
RGD:8655888
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Inha
inhibin alpha
ISO
RGD
PMID:15583806
RGD:2290390
NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010
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Jup
junction plakoglobin
disease_progression
ISO
RGD
PMID:16610682
RGD:2291882
NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589
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Kiss1
KiSS-1 metastasis-suppressor
disease_progression
ISO
RGD
PMID:15592684
RGD:2289400
NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460 Ensembl chr 1:133,237,565...133,257,460
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Kit
KIT proto-oncogene receptor tyrosine kinase
severity
ISO
RGD
PMID:16721362
RGD:2292426
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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Kndc1
kinase non-catalytic C-lobe domain (KIND) containing 1
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 7:139,474,612...139,521,453
Ensembl chr 7:139,474,612...139,521,450
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Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
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Map2k4
mitogen-activated protein kinase kinase 4
disease_progression
ISO
RGD
PMID:15592684
RGD:2289400
NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
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Met
met proto-oncogene
severity
ISO
protein:increased expression:tumor (human)
RGD
PMID:10590366
RGD:2317607
NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
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Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 7:111,825,032...112,012,311
Ensembl chr 7:111,825,063...112,012,313
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Mmp13
matrix metallopeptidase 13
disease_progression
ISO
RGD
PMID:11585740
RGD:2293606
NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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Ncoa4
nuclear receptor coactivator 4
ISO
protein:decreased expression:breast
RGD
PMID:11561770
RGD:2293536
NCBI chr14:31,881,884...31,901,210
Ensembl chr14:31,881,822...31,901,812
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Nefl
neurofilament, light polypeptide
ISO
DNA:loss of heterozygosity
RGD
PMID:8814452
RGD:2298999
NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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Nherf1
NHERF family PDZ scaffold protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28235801
NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
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Notch3
notch 3
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
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Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
ISO
mRNA,protein:increased expression:breast:
RGD
PMID:20802235
RGD:150520014
NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
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Nts
neurotensin
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347
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Pcna
proliferating cell nuclear antigen
severity
ISO
RGD
PMID:8102204
RGD:2315014
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Phf24
PHD finger protein 24
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 4:42,872,619...42,944,752
Ensembl chr 4:42,916,660...42,944,752
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Pml
promyelocytic leukemia
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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Prkci
protein kinase C, iota
disease_progression
ISO
protein:increased expression, altered localization:breast, cytoplasm
RGD
PMID:18538170
RGD:2314932
NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108
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Ptger1
prostaglandin E receptor 1 (subtype EP1)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11751431
NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21153458
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Rad50
RAD50 double strand break repair protein
ISO
RGD
PMID:14511253
RGD:2300250
NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
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Rad54l
RAD54 like (S. cerevisiae)
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
PMID:10362365
NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887
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Rnf212
ring finger protein 212
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 5:108,875,971...108,922,933
Ensembl chr 5:108,877,156...108,922,848
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Rp1
retinitis pigmentosa 1 (human)
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 1:4,185,896...4,479,508
Ensembl chr 1:4,069,780...4,479,464
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Rrp1
ribosomal RNA processing 1
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr10:78,236,196...78,248,877
Ensembl chr10:78,236,218...78,248,877
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Runx3
runt related transcription factor 3
disease_progression
ISO
DNA, protein:hypermethylation, altered localization:promoter
RGD
PMID:18256927
RGD:2302557
NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
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Serpinb5
serine (or cysteine) peptidase inhibitor, clade B, member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19944674
NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078
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Slitrk6
SLIT and NTRK-like family, member 6
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr14:110,984,770...110,992,640
Ensembl chr14:110,986,012...110,992,581
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Smad4
SMAD family member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20565773
NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
G
Socs1
suppressor of cytokine signaling 1
ISO
mRNA:increased expression:breast
RGD
PMID:12888825
RGD:2298909
NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
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Socs2
suppressor of cytokine signaling 2
ISO
mRNA:increased expression:breast
RGD
PMID:12888825
RGD:2298909
NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
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Socs3
suppressor of cytokine signaling 3
ISO
mRNA:increased expression:breast
RGD
PMID:12888825
RGD:2298909
NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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Sod2
superoxide dismutase 2, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23964924
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Spen
spen family transcription repressor
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 4:141,195,199...141,265,955
Ensembl chr 4:141,195,201...141,265,908
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Syt6
synaptotagmin VI
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 3:103,482,561...103,552,883
Ensembl chr 3:103,482,547...103,552,885
G
Tmbim6
transmembrane BAX inhibitor motif containing 6
disease_progression
ISO
RGD
PMID:17054309
RGD:2291958
NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930
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Tspan8
tetraspanin 8
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
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Tspear
thrombospondin type laminin G domain and EAR repeats
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
PMID:25741868
NCBI chr10:77,521,942...77,722,844
Ensembl chr10:77,522,403...77,722,855
G
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
ISO
DNA:mutation:CDS:multiple nonsynonymous mutations (human)
RGD
PMID:14871824
RGD:2306813
NCBI chr15:37,966,421...38,084,103
Ensembl chr15:37,967,572...38,079,098
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Vegfc
vascular endothelial growth factor C
disease_progression
ISO
RGD
PMID:19885590
RGD:2315471
NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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Wif1
Wnt inhibitory factor 1
ISO
protein:decreased expression:breast
RGD
PMID:14517837
RGD:727214
NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555
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Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
susceptibility
ISO
DNA:polymorphism: :p.R399Q
RGD
PMID:18752184
RGD:2302569
NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
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Yeats2
YEATS domain containing 2
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr16:19,959,803...20,051,323
Ensembl chr16:19,959,813...20,051,323
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Zdbf2
zinc finger, DBF-type containing 2
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 1:63,239,517...63,353,735
Ensembl chr 1:63,312,424...63,353,735
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Zfp420
zinc finger protein 420
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 7:29,559,392...29,576,727
Ensembl chr 7:29,559,404...29,576,717
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Zfp473
zinc finger protein 473
ISO
ClinVar Annotator: match by term: Breast cancer, invasive ductal
ClinVar
NCBI chr 7:44,380,904...44,398,041
Ensembl chr 7:44,380,904...44,400,474
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