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ONTOLOGY REPORT - ANNOTATIONS


Term:granulosa cell tumor
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Accession:DOID:2999 term browser browse the term
Definition:A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Synonyms:exact_synonym: Cancer of Granulosa Cells;   Granulosa Cell Cancer;   Granulosa Cell Cancers;   Granulosa Cell Tumors;   Granulosa Cells Cancer;   Granulosa Cells Cancers;   Granulosa cell neoplasm;   Granulosa cell tumor, adult type;   Granulosa cell tumor, somatic;   Granulosa cell tumour, sarcomatoid;   malignant granulosa cell neoplasm
 primary_id: MESH:D006106
 alt_id: RDO:0000751
 xref: NCI:C3070;   NCI:C4205
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granulosa cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amh anti-Mullerian hormone JBrowse link NW_004936588 1,342,791 1,345,746 RGD:9068941
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004936697 1,054,237 1,061,468 RGD:9068941
G Ccnd2 cyclin D2 JBrowse link NW_004936606 4,474,801 4,496,158 RGD:9068941
G Cmklr1 chemerin chemokine-like receptor 1 JBrowse link NW_004936769 302,391 304,166 RGD:9068941
G Ctnnb1 catenin beta 1 JBrowse link NW_004936473 29,999,542 30,034,610 RGD:9068941
G Fancf FA complementation group F JBrowse link NW_004936654 3,298,193 3,301,251 RGD:9068941
G Fhit fragile histidine triad diadenosine triphosphatase JBrowse link NW_004936473 397,140 1,424,805 RGD:9068941
G Fshr follicle stimulating hormone receptor JBrowse link NW_004936508 3,601,205 3,754,234 RGD:9068941
G Gnai2 G protein subunit alpha i2 JBrowse link NW_004936529 1,779,582 1,801,251 RGD:9068941
G Kit KIT proto-oncogene, receptor tyrosine kinase JBrowse link NW_004936482 17,162,854 17,238,319 RGD:9068941
G Lepr leptin receptor JBrowse link NW_004936591 5,771,371 5,846,177 RGD:9068941
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link NW_004936508 3,928,467 3,983,481 RGD:9068941
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link NW_004936486 16,744,607 16,923,209 RGD:9068941
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link NW_004936479 16,894,068 16,988,879 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004936481 3,821,564 3,828,086 RGD:9068941
G Rarres2 retinoic acid receptor responder 2 JBrowse link NW_004936527 5,949,161 5,952,367 RGD:9068941
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link NW_004936560 1,979,804 2,009,167 RGD:9068941
G Smad1 SMAD family member 1 JBrowse link NW_004936535 3,582,512 3,626,312 RGD:9068941
G Smad5 SMAD family member 5 JBrowse link NW_004936597 3,225,374 3,264,604 RGD:9068941
G St14 suppression of tumorigenicity 14 JBrowse link NW_004936572 2,137,820 2,182,674 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004936476 16,245,134 16,261,180 RGD:9068941
G Wif1 WNT inhibitory factor 1 JBrowse link NW_004936545 3,263,646 3,334,163 RGD:9068941
Granulosa Cell Tumor of the Ovary term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai2 G protein subunit alpha i2 JBrowse link NW_004936529 1,779,582 1,801,251 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11544
    disease of anatomical entity 11219
      endocrine system disease 3965
        endocrine gland cancer 1399
          ovarian cancer 212
            granulosa cell tumor 22
              Abrikosov's Tumor 0
              Granulosa Cell Tumor of the Ovary 1
              testicular granulosa cell tumor + 0
Path 2
Term Annotations click to browse term
  disease 11544
    disease of anatomical entity 11219
      Urogenital Diseases 3399
        Female Urogenital Diseases and Pregnancy Complications 1654
          Female Urogenital Diseases 1392
            female reproductive system disease 1388
              Adnexal Diseases 621
                ovarian disease 615
                  Ovarian Neoplasms 358
                    ovarian cancer 212
                      granulosa cell tumor 22
                        Abrikosov's Tumor 0
                        Granulosa Cell Tumor of the Ovary 1
                        testicular granulosa cell tumor + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.