RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: testicular cancer
Accession: DOID:2998
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Definition: A male reproductive system cancer that is located_in the testicles. (DO)
Synonyms: exact_synonym: cancer of testis; cancer of the testes; childhood neoplasm of the testis; malignant tumor of testis; pediatric testicular neoplasm; testicular cancers; testicular tumor; testis cancer; testis cancers
xref: GARD:7746 ; ICD10CM:C62 ; ICD9CM:186 ; NCI:C3404 ; NCI:C5053 ; NCI:C7251
For additional species annotation, visit the
Alliance of Genome Resources .
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BCL10
BCL10 immune signaling adaptor
ISO
ClinVar Annotator: match by term: Malignant tumor of testis
ClinVar
PMID:10582682
NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368
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FGFR3
fibroblast growth factor receptor 3
ISO
ClinVar Annotator: match by term: Cancer of the testes
ClinVar
PMID:1908846 PMID:7649548 PMID:7670477 PMID:7702086 PMID:7773297 PMID:7847369 PMID:7913883 PMID:8078586 PMID:8589699 PMID:8640234 PMID:8673103 PMID:8858131 PMID:9438390 PMID:9677066 PMID:10073901 PMID:10471491 PMID:10607835 PMID:10696568 PMID:10979354 PMID:11030304 PMID:11038465 PMID:11055896 PMID:11186939 PMID:11186940 PMID:11241532 PMID:11529856 PMID:11879084 PMID:12833394 PMID:15517832 PMID:15772091 PMID:16766665 PMID:16841094 PMID:17384684 PMID:17875876 PMID:18266238 PMID:18583390 PMID:18642369 PMID:19381019 PMID:19749790 PMID:20301331 PMID:20301540 PMID:20420824 PMID:20453470 PMID:20624921 PMID:21324899 PMID:21510009 PMID:21739570 PMID:22045636 PMID:23056398 PMID:25157968 PMID:25606676 PMID:25614871 PMID:25691418 PMID:25741868 PMID:25741914 PMID:25741916 PMID:25809207 PMID:26619011 PMID:26818779 PMID:28230213 PMID:28492532 PMID:28777845 PMID:29593476 PMID:29681095 PMID:30138938 PMID:30692697 PMID:31218223 PMID:31299979 PMID:31994750 PMID:32502767 PMID:33942288 More...
NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
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GSTP1
glutathione S-transferase pi 1
ISO
RGD
PMID:9111193
RGD:6906883
NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
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KIT
KIT proto-oncogene, receptor tyrosine kinase
ISO
ClinVar Annotator: match by term: Cancer of the testes | ClinVar Annotator: match by term: Malignant tumor of testis
ClinVar
PMID:25741868 PMID:28492532 PMID:28724667 PMID:31350202
NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
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SLCO1B2
solute carrier organic anion transporter family member 1B2
ISO
mRNA:decreased expression:testis (human)
RGD
PMID:21625523
RGD:152995425
NCBI chr27:26,411,008...26,496,174
Ensembl chr27:26,411,010...26,470,989
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STK11
serine/threonine kinase 11
ISO
ClinVar Annotator: match by term: Cancer of the testes | ClinVar Annotator: match by term: Malignant tumor of testis
ClinVar
PMID:9605748 PMID:9887330 PMID:25741868 PMID:26467025 PMID:28135145 PMID:28492532 PMID:33471991 More...
NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
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FGFR3
fibroblast growth factor receptor 3
ISO
ClinVar Annotator: match by term: Spermatocytic seminoma
ClinVar
PMID:7773297 PMID:8599935 PMID:8754806 PMID:9207791 PMID:9677066 PMID:10053006 PMID:10471491 PMID:11055896 PMID:11241532 PMID:11429702 PMID:12624096 PMID:15843401 PMID:16752380 PMID:16912704 PMID:19088846 PMID:19855393 PMID:20301540 PMID:20453470 PMID:20704477 PMID:21273588 PMID:21510009 PMID:23972473 PMID:24075385 PMID:25614871 PMID:25741868 PMID:28492532 PMID:31994750 PMID:33942288 PMID:34930662 More...
NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
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HRAS
HRas proto-oncogene, GTPase
ISO
ClinVar Annotator: match by term: Spermatocytic seminoma
ClinVar
PMID:12727991 PMID:19855393 PMID:25157968 PMID:31775759
NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
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LRRC56
leucine rich repeat containing 56
ISO
ClinVar Annotator: match by term: Spermatocytic seminoma
ClinVar
PMID:12727991 PMID:19855393 PMID:25157968 PMID:31775759
NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220
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FGFR3
fibroblast growth factor receptor 3
ISO
ClinVar Annotator: match by term: Germ cell tumor of testis
ClinVar
PMID:7647778 PMID:8723106 PMID:8841188 PMID:9042914 PMID:9107244 PMID:9207791 PMID:9279753 PMID:9279764 PMID:9525367 PMID:9580776 PMID:9585583 PMID:9600744 PMID:9843059 PMID:9857065 PMID:9950359 PMID:10053006 PMID:10094188 PMID:10425034 PMID:10671061 PMID:10861678 PMID:11424131 PMID:11746040 PMID:14613973 PMID:15241680 PMID:15915095 PMID:17509076 PMID:17552943 PMID:17875876 PMID:18076102 PMID:19088846 PMID:19215249 PMID:20301540 PMID:20301588 PMID:20301628 PMID:22016144 PMID:22622662 PMID:24728327 PMID:25614871 PMID:25728633 PMID:25741868 PMID:25741914 PMID:26740388 PMID:26818779 PMID:28492532 PMID:32238909 More...
NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
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KIT
KIT proto-oncogene, receptor tyrosine kinase
ISO
ClinVar Annotator: match by term: Germ cell tumor of testis
ClinVar
PMID:7530509 PMID:9438854 PMID:10362788 PMID:11276010 PMID:15790786 PMID:16731599 PMID:18955458 PMID:19164557 PMID:20147452 PMID:21642685 PMID:21690468 PMID:25157968 PMID:25741868 PMID:26822237 PMID:28492532 More...
NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
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STK11
serine/threonine kinase 11
ISO
ClinVar Annotator: match by term: Germ cell tumor of testis
ClinVar
PMID:25741868 PMID:26467025 PMID:28492532
NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
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MYD88
MYD88 innate immune signal transduction adaptor
ISO
associated with diffuse large B-cell lymphoma;DNA:missense mutation:CDS:p.L265P (human)
RGD
PMID:28868954
RGD:150524335
NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
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