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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:testicular cancer
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Accession:DOID:2998 term browser browse the term
Definition:A male reproductive system cancer that is located_in the testicles. (DO)
Synonyms:exact_synonym: cancer of testis;   cancer of the testes;   childhood neoplasm of the testis;   malignant tumor of testis;   pediatric testicular neoplasm;   testicular cancers;   testicular tumor;   testis cancer;   testis cancers
 xref: GARD:7746;   ICD10CM:C62;   ICD9CM:186;   NCI:C3404;   NCI:C5053;   NCI:C7251
For additional species annotation, visit the Alliance of Genome Resources.

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show annotations for term's descendants           Sort by:
testicular cancer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor ISO ClinVar Annotator: match by term: Malignant tumor of testis ClinVar PMID:10582682 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Cancer of the testes ClinVar PMID:1908846 PMID:7649548 PMID:7670477 PMID:7702086 PMID:7773297 More... NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:9111193 RGD:6906883 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Cancer of the testes | ClinVar Annotator: match by term: Malignant tumor of testis ClinVar PMID:25741868 PMID:28492532 PMID:28724667 PMID:31350202 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Cancer of the testes | ClinVar Annotator: match by term: Malignant tumor of testis ClinVar PMID:9605748 PMID:9887330 PMID:25741868 PMID:26467025 PMID:28135145 More... NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
spermatocytoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Spermatocytic seminoma ClinVar PMID:7773297 PMID:8599935 PMID:8754806 PMID:9207791 PMID:9677066 More... NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Spermatocytic seminoma ClinVar PMID:12727991 PMID:19855393 PMID:25157968 PMID:31775759 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Spermatocytic seminoma ClinVar PMID:12727991 PMID:19855393 PMID:25157968 PMID:31775759 NCBI chrNW_004955476:11,493,299...11,507,022
Ensembl chrNW_004955476:11,491,688...11,506,700 		JBrowse link
testicular germ cell cancer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:7647778 PMID:8723106 PMID:8841188 PMID:9042914 PMID:9107244 More... NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:7530509 PMID:9438854 PMID:10362788 PMID:11276010 PMID:15790786 More... NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
testicular lymphoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor ISO associated with diffuse large B-cell lymphoma;DNA:missense mutation:CDS:p.L265P (human) RGD PMID:28868954 RGD:150524335 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16063
    disease of anatomical entity 13820
      endocrine system disease 5500
        endocrine gland cancer 2144
          testicular cancer 8
            embryonal testis carcinoma + 0
            epididymal neoplasm 0
            malignant tumor of undescended testis 0
            spermatocytoma + 3
            testicular Brenner tumor 0
            testicular germ cell cancer + 3
            testicular granulosa cell tumor + 0
            testicular leukemia 0
            testicular lymphoma 1
            testicular trophoblastic tumor 0
            testis sarcoma + 0
Path 2
Term Annotations click to browse term
  disease 16063
    disease of anatomical entity 13820
      Urogenital Diseases 4394
        Male Urogenital Diseases 1777
          male reproductive system disease 1777
            Male Genital Neoplasms 1220
              Testicular Neoplasms 39
                testicular cancer 8
                  embryonal testis carcinoma + 0
                  epididymal neoplasm 0
                  malignant tumor of undescended testis 0
                  spermatocytoma + 3
                  testicular Brenner tumor 0
                  testicular germ cell cancer + 3
                  testicular granulosa cell tumor + 0
                  testicular leukemia 0
                  testicular lymphoma 1
                  testicular trophoblastic tumor 0
                  testis sarcoma + 0
paths to the root