adenocarcinoma - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	adenocarcinoma	go back to main search page
Accession:	DOID:299	browse the term
Definition:	A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue. (DO)
Synonyms:	exact_synonym:	adenocarcinomas; basal cell adenocarcinoma; basal cell adenocarcinomas; cribriform carcinoma; cribriform carcinomas; oxyphilic adenocarcinoma; oxyphilic adenocarcinomas
	primary_id:	MESH:D000230
	xref:	EFO:0000228; ICDO:8140/3; NCI:C2852
For additional species annotation, visit the Alliance of Genome Resources.

GViewer not supported for the selected species.

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Rat (1882) Mouse (1959) Human (15066) Chinchilla (1483) Bonobo (1573) Dog (1645) Squirrel (1510) Pig (1593) Green Monkey (1546) Naked Mole-rat (1468) All
Genes (1510)

adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669

G

AKT serine/threonine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

AKT serine/threonine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936661:2,652,568...2,694,039
Ensembl chrNW_004936661:2,652,566...2,694,086

G

arachidonate 12-lipoxygenase, 12R type

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985

G

arachidonate 5-lipoxygenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

angiopoietin 2

protein:increased expression:cerebrum, blood vessels (rat)

NCBI chrNW_004936615:4,472,261...4,524,537
Ensembl chrNW_004936615:4,472,247...4,524,556

G

APC regulator of WNT signaling pathway

DNA:frameshift mutations, nonsense mutations:exon:multiple (human)
CTD Direct Evidence: marker/mechanism

PMID:9111214 PMID:11677205 PMID:15639718

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

apolipoprotein A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854

G

apolipoprotein E

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936706:1,512,438...1,516,805

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,148,857...11,197,312

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Adenocarcinoma

PMID:9443866 PMID:9536098 PMID:9887333 PMID:10330348 PMID:10817650 More...

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

alpha-2-glycoprotein 1, zinc-binding

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190

G

BCL2 apoptosis regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

baculoviral IAP repeat containing 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

carbonic anhydrase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936544:246,797...257,798
Ensembl chrNW_004936544:246,797...257,650

G

carbonic anhydrase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936544:362,591...379,151
Ensembl chrNW_004936544:362,591...380,223

G

caspase 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922

G

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936560:42,561...45,748
Ensembl chrNW_004936560:42,537...45,807

G

cyclin D1

CTD Direct Evidence: marker/mechanism

Ensembl chrNW_004936599:973,838...983,316

G

cyclin dependent kinase inhibitor 1C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936794:1,023,891...1,025,470

G

creatine kinase B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:1,612,398...1,615,821
Ensembl chrNW_004936621:1,612,393...1,615,822

G

catenin beta 1

CTD Direct Evidence: marker/mechanism

PMID:10965019 PMID:14507667 PMID:15459021

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Adenocarcinoma

PMID:9443866 PMID:9536098 PMID:9887333 PMID:10330348 PMID:10817650 More...

NCBI chrNW_004936551:305,617...343,369
Ensembl chrNW_004936551:305,611...351,063

G

death associated protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936680:2,842,930...3,020,757
Ensembl chrNW_004936680:2,842,547...3,021,058

G

discoidin domain receptor tyrosine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833

G

DNA methyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

eukaryotic translation elongation factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

EGF containing fibulin extracellular matrix protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:2,159,654...2,214,480
Ensembl chrNW_004936491:2,159,096...2,214,677

G

epidermal growth factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936563:1,058,803...1,181,393

G

epidermal growth factor receptor

CTD Direct Evidence: marker/mechanism

PMID:2523869 PMID:20934974 PMID:21541241 PMID:22042947 PMID:27720938

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

enolase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183

G

erb-b2 receptor tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

PMID:21673877 PMID:22042947

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:15639718 PMID:20458558

NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171

G

estrogen receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:7,956,168...8,018,356
Ensembl chrNW_004936495:7,956,766...8,004,357

G

FAT atypical cadherin 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936662:3,537,917...3,704,012
Ensembl chrNW_004936662:3,537,925...3,690,877

G

flap structure-specific endonuclease 1

susceptibility

NCBI chrNW_004936581:1,328,685...1,332,713
Ensembl chrNW_004936581:1,328,685...1,332,728

G

fibroblast growth factor 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936720:282,291...316,629
Ensembl chrNW_004936720:279,521...316,674

G

gastrin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:16,636,146...16,636,548
Ensembl chrNW_004936490:16,636,146...16,636,548

G

ghrelin and obestatin prepropeptide

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:3,037,862...3,044,863
Ensembl chrNW_004936602:3,038,549...3,042,506

G

gastrokine 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:13,259,073...13,264,213
Ensembl chrNW_004936491:13,259,073...13,264,213

G

guanosine monophosphate reductase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936722:323,917...330,648

G

glutathione peroxidase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

growth factor receptor bound protein 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337

G

histone deacetylase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936504:12,530,546...12,546,556
Ensembl chrNW_004936504:12,530,528...12,546,556

G

heme oxygenase 1

susceptibility

Lung Adenocarcinoma; DNA:allele:promoter:L allele of the (GT)n repeat (>30 repeats)

NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311

G

homeobox A10

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:3,798,679...3,802,007

G

histamine receptor H4

CTD Direct Evidence: marker/mechanism

G

heat shock protein family A (Hsp70) member 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:7,577,192...7,581,598
Ensembl chrNW_004936542:7,577,149...7,581,923

G

heat shock protein family D (Hsp60) member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936506:1,678,069...1,687,632

G

inhibitor of DNA binding 3, HLH protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:8,758,098...8,759,684
Ensembl chrNW_004936474:8,758,030...8,759,823

G

interleukin 1 beta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165

G

potassium voltage-gated channel subfamily Q member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936794:707,122...994,206
Ensembl chrNW_004936794:707,119...994,778

G

kinase insert domain receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

lysine methyltransferase 2A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:3,480,071...3,566,823
Ensembl chrNW_004936542:3,391,774...3,562,147

G

lysine methyltransferase 2C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365

G

KRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

PMID:11745231 PMID:16247444 PMID:20101149

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

keratin 20

CTD Direct Evidence: marker/mechanism

G

keratin 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:10,247,049...10,254,748
Ensembl chrNW_004936512:10,246,991...10,254,827

G

CEA cell adhesion molecule 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936706:37,480...53,306

G

aromatase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:13,107,603...13,136,910
Ensembl chrNW_004936471:13,107,603...13,136,910

G

cytochrome P450 7B1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936496:8,900,320...9,072,109
Ensembl chrNW_004936496:8,899,965...9,072,089

G

interleukin-8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353

G

angiotensin-converting enzyme

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177

G

cytochrome P450 2E1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102

G

cytochrome P450 26A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074

G

leukotriene A4 hydrolase

protein:increased expression:esophagus (rat)

NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091

G

MET proto-oncogene, receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

PMID:20934974 PMID:22042947

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

marker of proliferation Ki-67

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:15,561,327...15,587,109

G

matrix metallopeptidase 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611

G

MAGUK p55 scaffold protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936927:147,448...170,435
Ensembl chrNW_004936927:147,282...170,575

G

mechanistic target of rapamycin kinase

CTD Direct Evidence: marker/mechanism

PMID:18058806 PMID:33129824

NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342

G

mucin 2, oligomeric mucus/gel-forming

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936816:60,499...91,628
Ensembl chrNW_004936816:60,499...91,628

G

MYC proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

nuclear receptor coactivator 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936514:5,900,135...5,967,862
Ensembl chrNW_004936514:5,901,601...5,967,865

G

nuclear factor kappa B subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435

G

nitric oxide synthase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534

G

natriuretic peptide A

CTD Direct Evidence: therapeutic

NCBI chrNW_004936474:671,362...673,610

G

nuclear receptor subfamily 1 group I member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936536:6,691,590...6,726,421
Ensembl chrNW_004936536:6,691,590...6,726,704

G

8-oxoguanine DNA glycosylase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

pro-apoptotic WT1 regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057

G

proliferating cell nuclear antigen

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936485:13,766,221...13,771,215

G

phosphoglycerate mutase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936636:2,240,452...2,248,689
Ensembl chrNW_004936636:2,236,508...2,248,768

G

progesterone receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936551:6,498,553...6,573,212
Ensembl chrNW_004936551:6,498,553...6,573,222

G

prohibitin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:12,127,065...12,138,870
Ensembl chrNW_004936490:12,127,065...12,138,870

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

plasminogen activator, urokinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877

G

phospholipase C epsilon 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:817,151...1,105,824
Ensembl chrNW_004936601:816,190...1,105,830

G

peroxisome proliferator activated receptor gamma

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743

G

protein kinase D1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936494:4,469,092...4,601,183
Ensembl chrNW_004936494:4,469,089...4,601,214

G

prolactin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936552:7,204,298...7,212,632

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

prostaglandin E receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:3,014,633...3,018,617
Ensembl chrNW_004936659:3,012,012...3,018,275

G

prostaglandin-endoperoxide synthase 2

associated with Esophageal Neoplasms
CTD Direct Evidence: marker/mechanism

PMID:10485483 PMID:16820089 PMID:17675820

NCBI chrNW_004936481:3,821,564...3,828,086

G

protein tyrosine phosphatase non-receptor type 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936668:2,602,261...2,687,903
Ensembl chrNW_004936668:2,628,706...2,682,448

G

PYD and CARD domain containing

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805

G

receptor activity modifying protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:17,479,899...17,481,788
Ensembl chrNW_004936490:17,479,650...17,482,716

G

retinoic acid receptor beta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885

G

Ras association domain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:1,857,177...1,866,198
Ensembl chrNW_004936529:1,857,145...1,867,260

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813

G

roundabout guidance receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936505:4,329,428...4,711,310
Ensembl chrNW_004936505:4,330,303...4,709,655

G

RUNX family transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910

G

selenium binding protein 1

CTD Direct Evidence: marker/mechanism

PMID:14991897 PMID:15378696

NCBI chrNW_004936580:1,573,208...1,584,266
Ensembl chrNW_004936580:1,573,150...1,581,921

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

sphingosine kinase 1

protein, mRNA:increased expression:colon mucosa (rat)

NCBI chrNW_004936594:1,482,830...1,489,337
Ensembl chrNW_004936594:1,486,111...1,489,188

G

secreted phosphoprotein 1

CTD Direct Evidence: marker/mechanism

PMID:20495387 PMID:21552421

NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

PMID:19028472 PMID:26432044

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

G

serine/threonine kinase 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:579,816...601,033
Ensembl chrNW_004936588:579,816...603,654

G

serine/threonine kinase receptor associated protein

NCBI chrNW_004936587:1,679,570...1,700,610
Ensembl chrNW_004936587:1,678,439...1,701,216

G

synaptonemal complex protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936627:239,232...365,062

G

transcription factor 7 like 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:3,473,877...3,660,565
Ensembl chrNW_004936486:3,473,843...3,660,576

G

transforming growth factor beta 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

tumor necrosis factor

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:1733439 PMID:19028472

NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766

G

tumor protein p53

ClinVar Annotator: match by term: Adenocarcinoma

PMID:1565143 PMID:1591732 PMID:2046748 PMID:4122735 PMID:7565304 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor protein p63

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:492,267...705,282
Ensembl chrNW_004936578:491,507...705,729

G

tropomyosin 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:3,860,185...3,893,251
Ensembl chrNW_004936580:3,860,190...3,889,978

G

tyrosinase related protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936539:6,537,448...6,555,440
Ensembl chrNW_004936539:6,537,509...6,556,513

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

vesicle transport through interaction with t-SNAREs 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:3,010,169...3,353,512
Ensembl chrNW_004936486:3,010,490...3,347,424

acinar cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

DNA:mutations (human)

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

adenocarcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

FA complementation group F

disease_progression

DNA:hypermethylation:promoter:

NCBI chrNW_004936654:3,298,193...3,301,251

adenosquamous gallbladder carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

discoidin domain receptor tyrosine kinase 2

disease_progression

NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139

adenosquamous lung carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

transthyretin

protein:increased expression:lung (human)

NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566

adrenocortical carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427

G

ATRX chromatin remodeler

ClinVar Annotator: match by term: Adrenal cortex carcinoma | ClinVar Annotator: match by term: Adrenocortical carcinoma

PMID:15591283 PMID:18409179 PMID:23681356 PMID:28492532

NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

baculoviral IAP repeat containing 2

exacerbates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936551:5,515,904...5,535,864

G

baculoviral IAP repeat containing 3

ameliorates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

exacerbates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

baculoviral IAP repeat containing 6

exacerbates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936493:903,295...1,115,434
Ensembl chrNW_004936493:899,961...1,115,493

G

baculoviral IAP repeat containing 7

ameliorates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

B-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

basigin (Ok blood group)

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287

G

checkpoint kinase 2

ClinVar Annotator: match by term: Adrenal cortex carcinoma

PMID:10617473 PMID:11053450 PMID:11298456 PMID:11390408 PMID:11461078 More...

NCBI chrNW_004936657:2,805,947...2,848,180
Ensembl chrNW_004936657:2,805,959...2,848,180

G

catenin beta 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

death domain associated protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:25,546,091...25,550,390
Ensembl chrNW_004936476:25,546,036...25,550,392

G

epidermal growth factor receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

insulin like growth factor 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

insulin like growth factor 2

CTD Direct Evidence: marker/mechanism

PMID:21521927 PMID:23417626

NCBI chrNW_004936816:972,902...981,232
Ensembl chrNW_004936816:972,282...979,167

G

mediator complex subunit 12

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936762:460,342...483,264
Ensembl chrNW_004936762:460,342...483,195

G

menin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

RB transcriptional corepressor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846

G

ribonucleotide reductase catalytic subunit M1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793

G

secreted protein acidic and cysteine rich

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936515:11,026,156...11,046,812
Ensembl chrNW_004936515:11,025,724...11,046,849

G

telomerase reverse transcriptase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

DNA topoisomerase II alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978

G

tumor protein p53

ClinVar Annotator: match by term: Adrenal cortex carcinoma | ClinVar Annotator: match by term: Adrenocortical carcinoma

PMID:1349102 PMID:1565143 PMID:1683921 PMID:1849234 PMID:1978757 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

X-linked inhibitor of apoptosis

ameliorates

mRNA:increased expression:adrenal gland (human)

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

G

zinc and ring finger 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936657:3,064,199...3,119,903
Ensembl chrNW_004936657:3,064,201...3,119,684

aflatoxins-related hepatocellular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

epoxide hydrolase 1

associated with estrogen excess;protein:increased activity;liver (rat)

NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286

G

gamma-glutamyltransferase 1

associated with estrogen excess;protein:increased activity;liver (rat)

NCBI chrNW_004936619:762,278...791,610

Barrett's adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione peroxidase 3

DNA:hypermethylation:promoter

PMID:16229808 PMID:18664505

RGD:151665354 RGD:151665749

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

glutathione peroxidase 7

DNA:hypermethylation:promoter

NCBI chrNW_004936522:8,381,678...8,388,800
Ensembl chrNW_004936522:8,381,377...8,389,357

G

cytochrome P450 26A1

NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074

bile duct adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

solute carrier family 7 member 5

disease_progression

NCBI chrNW_004936641:1,513,110...1,538,955

breast adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

ClinVar Annotator: match by term: Breast adenocarcinoma

PMID:17611497 PMID:18954143 PMID:21793738 PMID:23237847 PMID:25741868 More...

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

BRCA1 DNA repair associated

treatment

NCBI chrNW_004936490:17,735,444...17,801,456

G

catalase

NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422

G

cyclin E1

DNA:amplification

NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008

G

cyclin G1

mRNA, protein:altered expression:mammary (mouse)

NCBI chrNW_004936515:614,287...621,213
Ensembl chrNW_004936515:614,290...619,963

G

fibroblast growth factor receptor 3

no_association

DNA:mutation:exons:no mutations found in mutation hotspots in exons 7, 10 or 15

NCBI chrNW_004936477:21,591,772...21,606,289
Ensembl chrNW_004936477:21,591,792...21,606,296

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Breast adenocarcinoma, somatic

PMID:2547513 PMID:3627975 PMID:15696205 PMID:17332249 PMID:21063026 More...

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

kinase suppressor of ras 1

severity

NCBI chrNW_004936538:3,945,411...4,006,300
Ensembl chrNW_004936538:3,863,771...4,011,649

G

cytochrome P450 1B1

mRNA:increased expression:mammary epithelium (rat)

NCBI chrNW_004936663:345,021...355,188
Ensembl chrNW_004936663:348,368...355,191

G

mucin 1, cell surface associated

mRNA,protein:increased expression:breast

NCBI chrNW_004936580:4,691,870...4,694,092

G

MAX interactor 1, dimerization protein

NCBI chrNW_004936486:1,103,908...1,173,982
Ensembl chrNW_004936486:1,101,552...1,177,220

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Breast adenocarcinoma | ClinVar Annotator: match by term: Breast adenocarcinoma, somatic

PMID:15016963 PMID:15520168 PMID:15608678 PMID:15930273 PMID:17673550 More...

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

RB1 inducible coiled-coil 1

ClinVar Annotator: match by term: Breast adenocarcinoma

NCBI chrNW_004936590:260,685...335,143
Ensembl chrNW_004936590:260,685...334,721

G

solute carrier family 67 member 1

ClinVar Annotator: match by term: Breast adenocarcinoma

NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345

G

tumor necrosis factor

human protein in a rat model

NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766

G

tumor protein p53

ClinVar Annotator: match by term: Breast adenocarcinoma

PMID:1673792 PMID:1686725 PMID:7881428 PMID:8364550 PMID:10713666 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

breast ductal carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 9

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936548:4,983,461...5,110,693
Ensembl chrNW_004936548:4,987,847...5,108,104

G

arachidonate 5-lipoxygenase

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

autocrine motility factor receptor

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936475:8,692,969...8,727,252
Ensembl chrNW_004936475:8,692,844...8,727,385

G

BCAR1 scaffold protein, Cas family member

NCBI chrNW_004936475:23,994,130...24,032,829
Ensembl chrNW_004936475:23,992,193...24,033,031

G

BRCA1 DNA repair associated

ClinVar Annotator: match by term: Ductal breast carcinoma

PMID:9063749 PMID:10196379 PMID:11400546 PMID:14555511 PMID:15235020 More...

NCBI chrNW_004936490:17,735,444...17,801,456

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Ductal breast carcinoma

PMID:11062481 PMID:11927503 PMID:14555511 PMID:15235023 PMID:17767707 More...

NCBI chrNW_004936472:26,945,659...27,017,693

G

basigin (Ok blood group)

mRNA:increased expression:breast

NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287

G

calcium voltage-gated channel subunit alpha1 C

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936606:2,168,104...2,867,560
Ensembl chrNW_004936606:2,168,625...2,865,758

G

calcium voltage-gated channel subunit alpha1 H

ClinVar Annotator: match by term: Ductal breast carcinoma

PMID:26467025 PMID:27148582 PMID:28492532

NCBI chrNW_004936694:2,702,224...2,724,574

G

coiled-coil domain containing 180

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936524:6,168,334...6,230,934
Ensembl chrNW_004936524:6,168,938...6,230,925

G

coiled-coil domain containing 71 like

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004939850:3,101...4,265
Ensembl chrNW_004939850:3,547...4,283

G

CD44 molecule (IN blood group)

disease_progression

mRNA, protein:splice variant, increased expression:breast

NCBI chrNW_004936533:2,949,026...3,033,166

G

cyclin and CBS domain divalent metal cation transport mediator 1

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936636:646,309...699,768
Ensembl chrNW_004936636:644,876...699,824

G

coronin 6

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936538:5,724,336...5,732,487
Ensembl chrNW_004936538:5,723,994...5,732,525

G

C3 and PZP like alpha-2-macroglobulin domain containing 8

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936596:3,756,446...3,819,840

G

carboxypeptidase X, M14 family member 2

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936486:12,250,128...12,335,578
Ensembl chrNW_004936486:12,251,199...12,345,542

G

cAMP responsive element binding protein 3

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936524:3,727,104...3,730,962
Ensembl chrNW_004936524:3,727,098...3,730,975

G

estrogen receptor binding site associated antigen 9

severity

protein:increased expression:breast

NCBI chrNW_004936470:35,449,920...35,473,635
Ensembl chrNW_004936470:35,450,292...35,473,110

G

far upstream element binding protein 1

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942

G

HtrA serine peptidase 2

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936556:741,718...746,016
Ensembl chrNW_004936556:741,718...749,090

G

kinase non-catalytic C-lobe domain containing 1

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936486:19,287,468...19,341,127
Ensembl chrNW_004936486:19,287,462...19,341,145

G

keratin-associated protein 10-12

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936778:1,582,160...1,583,314

G

lecithin retinol acyltransferase

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936576:1,491,480...1,498,568
Ensembl chrNW_004936576:1,492,297...1,501,917

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936528:6,217,130...6,349,891
Ensembl chrNW_004936528:6,217,112...6,349,937

G

notch receptor 3

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429

G

neurotensin

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936507:3,318,982...3,329,248
Ensembl chrNW_004936507:3,318,915...3,329,342

G

PHD finger protein 24

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936524:3,020,421...3,031,720
Ensembl chrNW_004936524:3,005,705...3,031,744

G

polo like kinase 4

protein:increased expression:breast

NCBI chrNW_004936642:2,837,041...2,855,369
Ensembl chrNW_004936642:2,837,022...2,855,103

G

PML nuclear body scaffold

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936471:33,135,186...33,173,218
Ensembl chrNW_004936471:33,135,164...33,177,666

G

RAD54 like

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936474:27,276,570...27,316,427
Ensembl chrNW_004936474:27,280,573...27,316,428

G

RPTOR independent companion of MTOR complex 2

human cells in mouse model

NCBI chrNW_004936518:3,198,312...3,314,393
Ensembl chrNW_004936518:3,198,337...3,310,000

G

ring finger protein 212

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936477:22,122,854...22,173,324

G

RP1 axonemal microtubule associated

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936496:1,524,123...1,583,114

G

ribosomal RNA processing 1

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936500:475,213...488,475
Ensembl chrNW_004936500:475,178...488,514

G

solute carrier organic anion transporter family member 1B3

disease_progression

protein:decreased expression:breast (human)

NCBI chrNW_004936548:5,593,908...5,682,187

G

SLIT and NTRK like family member 6

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936866:412,719...419,381
Ensembl chrNW_004936866:412,818...419,381

G

spen family transcriptional repressor

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936474:3,473,892...3,535,307
Ensembl chrNW_004936474:3,473,901...3,534,628

G

synaptotagmin 6

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936690:2,435,573...2,497,332
Ensembl chrNW_004936690:2,435,541...2,497,553

G

tumor protein p73

mRNA:decreased expression:breast

NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464

G

tetraspanin 8

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936568:285,130...304,479
Ensembl chrNW_004936568:285,696...311,864

G

thrombospondin type laminin G domain and EAR repeats

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936778:1,576,580...1,660,344
Ensembl chrNW_004936778:1,478,617...1,660,331

G

X-linked inhibitor of apoptosis

severity

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

G

YEATS domain containing 2

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936578:6,004,427...6,075,414
Ensembl chrNW_004936578:6,006,018...6,075,449

G

zinc finger DBF-type containing 2

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936631:2,649,792...2,686,430
Ensembl chrNW_004936631:2,648,381...2,686,434

G

zinc finger protein 420

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936801:338,743...403,206

G

zinc finger protein 473

ClinVar Annotator: match by term: Ductal breast carcinoma

NCBI chrNW_004936889:39,812...56,052
Ensembl chrNW_004936889:41,119...57,582

breast lobular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin II receptor type 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936479:13,252,678...13,255,570
Ensembl chrNW_004936479:13,252,678...13,255,570

G

cadherin 1

ClinVar Annotator: match by term: Breast lobular carcinoma

PMID:8557030 PMID:9744472 PMID:15235021 PMID:20373070 PMID:28492532 More...

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

myosin heavy chain 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:4,384,215...4,466,229
Ensembl chrNW_004936492:4,384,215...4,466,262

G

protein phosphatase 1 regulatory subunit 12B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936567:1,992,487...2,208,611
Ensembl chrNW_004936567:1,992,495...2,208,684

G

tumor protein p53 binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936526:936,981...1,000,070
Ensembl chrNW_004936526:936,359...1,000,076

bronchiolo-alveolar adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ALX homeobox 4

ameliorates

NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000

G

cyclin D1

protein:increased expression:lung

Ensembl chrNW_004936599:973,838...983,316

G

DNA methyltransferase 1

disease_progression

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

epidermal growth factor receptor

DNA:mutations:exons:
DNA:snp:cds:p.T790M (human)
protein:increased expression:tumor (human)

PMID:15737014 PMID:21419590 PMID:26059825

RGD:11075076 RGD:5131465 RGD:5131630

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

early growth response 1

mRNA:decreased expression:tumor (human)

NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749

G

glutathione S-transferase pi 1

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

KRAS proto-oncogene, GTPase

DNA:mutations:cds:

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

tumor protein p53

DNA:mutations:exons:

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

Carcinoid Tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

enolase 2

NCBI chrNW_004936709:904,647...913,445
Ensembl chrNW_004936709:904,031...913,451

G

menin 1

DNA:loss of heterozygosity:lung:PYGM,D11S449,D11S906(human)

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

O-6-methylguanine-DNA methyltransferase

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

regenerating family member 1 alpha

associated with Hypergastrinemia;DNA:missense mutations:cds:multiple (human)

NCBI chrNW_004936556:4,873,331...4,875,608
Ensembl chrNW_004936556:4,873,331...4,875,608

cervical adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

serine peptidase inhibitor Kazal type 1

NCBI chrNW_004936504:6,975,044...6,981,304
Ensembl chrNW_004936504:6,975,044...6,981,304

G

transferrin receptor

protein:increased expression:uterine cervix

NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543

G

tumor protein p53

disease_progression

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

cervical mucinous adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

serine/threonine kinase 11

disease_progression

DNA:mutations

NCBI chrNW_004936588:579,816...601,033
Ensembl chrNW_004936588:579,816...603,654

childhood hepatocellular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

MET proto-oncogene, receptor tyrosine kinase

ClinVar Annotator: match by term: Pediatric hepatocellular carcinoma

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

childhood kidney cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

dicer 1, ribonuclease III

ClinVar Annotator: match by term: Childhood kidney cell carcinoma

PMID:25741868 PMID:28492532

NCBI chrNW_004936846:528,768...584,599
Ensembl chrNW_004936846:532,972...575,689

cholangiocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 2

susceptibility

DNA:polymorphism:exon:c.3972C>T (human)

NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393

G

adrenoceptor beta 2

protein:decreased expression:liver

NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210

G

arachidonate 5-lipoxygenase

protein:increased expression:bile duct

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

annexin A2

disease_progression

NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503

G

APC regulator of WNT signaling pathway

DNA:hypermethylation:promoter
DNA:loss of heterozygosity

PMID:10212000 PMID:15467712

RGD:2317198 RGD:2317205

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

apolipoprotein A1

protein:decreased expression:serum

NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,148,857...11,197,312

G

aspartate beta-hydroxylase

NCBI chrNW_004936496:11,604,992...11,815,680
Ensembl chrNW_004936496:11,604,680...11,816,852

G

autophagy related 101

disease_progression

NCBI chrNW_004936512:9,518,128...9,525,986
Ensembl chrNW_004936512:9,518,074...9,526,961

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

PMID:24185509 PMID:25231345

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

baculoviral IAP repeat containing 6

ameliorates

mRNA:increased expression:bile duct (human)

NCBI chrNW_004936493:903,295...1,115,434
Ensembl chrNW_004936493:899,961...1,115,493

G

B-Raf proto-oncogene, serine/threonine kinase

DNA:missense mutation:cds:p.V600E (human)

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

C-X-C motif chemokine receptor 1

ClinVar Annotator: match by term: Cholangiocarcinoma

NCBI chrNW_004936569:715,129...716,187
Ensembl chrNW_004936569:715,129...716,181

G

epidermal growth factor

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:18550579 PMID:25741868 PMID:28492532

NCBI chrNW_004936563:1,058,803...1,181,393

G

epidermal growth factor receptor

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:18550579 PMID:24728327 PMID:25741868 PMID:28492532

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

erythropoietin

mRNA, protein:increased expression:liver

NCBI chrNW_004936543:742,722...745,332
Ensembl chrNW_004936543:743,537...745,343

G

erythropoietin receptor

mRNA, protein:increased expression:liver

NCBI chrNW_004936659:1,468,391...1,473,880
Ensembl chrNW_004936659:1,468,634...1,473,880

G

erb-b2 receptor tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

disease_progression
no_association

DNA:SNP: :g.148505302C>T (rs887569) (human)
DNA:SNPs: :g.148525904C>G, (rs2302427), g.148519011C>T (rs6464926), g.148517456T>G (rs17171119) (human)

NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939

G

Fas ligand

NCBI chrNW_004936481:14,789,547...14,795,780

G

fibroblast growth factor receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019

G

fascin actin-bundling protein 1

disease_progression

protein:increased expression:bile ducts

NCBI chrNW_004936765:609,894...619,417
Ensembl chrNW_004936765:609,861...619,456

G

glutathione S-transferase pi 1

treatment

human cell line in a mouse model
DNA:hypermethylation:promoter

PMID:12805482 PMID:15467712

RGD:14401711 RGD:2317198

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

histone deacetylase 6

protein:increased expression:liver:

NCBI chrNW_004936721:757,500...778,416
Ensembl chrNW_004936721:758,181...778,053

G

hepatocyte growth factor

protein:increased expression:serum
mRNA, protein:increased expression: :

PMID:10827151 PMID:16974053

RGD:2317909 RGD:2317925

NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779

G

hypoxia inducible factor 1 subunit alpha

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:12919954 PMID:18550579 PMID:22647679 PMID:24120591 PMID:25741868

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

isocitrate dehydrogenase (NADP(+)) 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

G

isocitrate dehydrogenase (NADP(+)) 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341

G

interleukin 10

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:11121048 PMID:14657422 PMID:14657427 PMID:18550579 PMID:25741868 More...

NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502

G

interleukin 19

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:11121048 PMID:14657422 PMID:14657427 PMID:18550579 PMID:25741868 More...

NCBI chrNW_004936557:5,765,093...5,769,853
Ensembl chrNW_004936557:5,765,093...5,769,853

G

interleukin 1 beta

ClinVar Annotator: match by term: Cholangiocarcinoma

NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165

G

interleukin 1 receptor type 2

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936713:679,680...716,801
Ensembl chrNW_004936713:701,155...716,650

G

interleukin 4 receptor

mRNA:increased expression:bile duct

NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818

G

interleukin 6

ClinVar Annotator: match by term: Cholangiocarcinoma

PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More...

NCBI chrNW_004936549:7,015,595...7,016,246

G

insulin

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357

G

potassium voltage-gated channel subfamily D member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936605:4,370,222...4,828,972
Ensembl chrNW_004936605:4,372,671...4,825,423

G

KIT proto-oncogene, receptor tyrosine kinase

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274

G

lysine methyltransferase 2C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365

G

KRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

PMID:8968066 PMID:22561520

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

keratin 7

NCBI chrNW_004936512:9,641,587...9,656,573
Ensembl chrNW_004936512:9,641,587...9,656,524

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

protein:increased expression:intrahepatic bile, extrahepatic bile duct (human)

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

G

mucin-3B

mRNA:decreased expression:bile duct

NCBI chrNW_004936543:886,333...904,504

G

interleukin-8

ClinVar Annotator: match by term: Cholangiocarcinoma

NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353

G

neuroendocrine secretory protein 55

disease_progression

DNA:polymorphism:393T>C (human)
CTD Direct Evidence: marker/mechanism

PMID:17356712 PMID:22561520

NCBI chrNW_004936530:1,353,432...1,407,437

G

MDM2 proto-oncogene

disease_progression

protein:increased expression:intrahepatic bile duct (human)

NCBI chrNW_004936545:6,709,903...6,732,334

G

MET proto-oncogene, receptor tyrosine kinase

disease_progression

protein:increased phosphorylation:liver, carcinoma (human)
protein:increased expression:liver, biliary epithelium (rat)

PMID:14656942 PMID:16818635

RGD:2317578 RGD:2317601

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

major facilitator superfamily domain containing 4A

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936557:6,823,771...6,852,534
Ensembl chrNW_004936557:6,823,597...6,842,741

G

O-6-methylguanine-DNA methyltransferase

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

marker of proliferation Ki-67

disease_progression

NCBI chrNW_004936486:15,561,327...15,587,109

G

matrix metallopeptidase 2

disease_progression

protein:increased expression:bile duct

PMID:15213623 PMID:19629755

RGD:2324667 RGD:2325769

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

protein:increased expression:bile duct
mRNA:increased expression:bile duct

PMID:15213623 PMID:16463672

RGD:2324667 RGD:2325856

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

methylenetetrahydrofolate reductase

susceptibility

DNA:polymorphism (human)

NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193

G

mucin 1, cell surface associated

disease_progression

mRNA:increased expression:bile duct
protein:increased expression:bile duct:
protein:increased expression:serum
protein:increased secretion:bile

PMID:15213623 PMID:18081149 PMID:19055478 PMID:19260467 PMID:19639217

RGD:2317986 RGD:2324622 RGD:2324638 RGD:2324664 RGD:2324667

NCBI chrNW_004936580:4,691,870...4,694,092

G

mucin 16, cell surface associated

associated with Opisthorchiasis;protein:increased expression:serum

NCBI chrNW_004936588:5,506,683...5,586,450

G

mucin 2, oligomeric mucus/gel-forming

mRNA:decreased expression:bile duct

NCBI chrNW_004936816:60,499...91,628
Ensembl chrNW_004936816:60,499...91,628

G

mucin 4, cell surface associated

disease_progression

protein:increased expression:bile duct

PMID:14752841 PMID:19082442

RGD:2303602 RGD:2324944

NCBI chrNW_004936784:515,608...539,915

G

mucin 5AC, oligomeric mucus/gel-forming

disease_progression

protein:increased expression:serum
mRNA:increased expression:bile duct

PMID:11680592 PMID:14508831

RGD:2324948 RGD:2324990

NCBI chrNW_004936816:129,926...159,396

G

mucin 5B, oligomeric mucus/gel-forming

mRNA:decreased expression:bile duct

NCBI chrNW_004936816:174,943...209,241

G

mucin 6, oligomeric mucus/gel-forming

protein:increased expression: :

NCBI chrNW_004936816:882...14,717

G

neural cell adhesion molecule 1

associated with hepatitis

NCBI chrNW_004936612:1,262,557...1,556,281
Ensembl chrNW_004936612:1,262,544...1,556,016

G

nitric oxide synthase 2

protein:increased expression:bile duct
CTD Direct Evidence: marker/mechanism

PMID:16094703 PMID:16818635

NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051

G

notch receptor 1

protein:increased expression:cholangiocyte

NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428

G

nuclear receptor subfamily 1 group H member 4

disease_progression

mRNA:decreased expression:liver (rat)

NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034

G

8-oxoguanine DNA glycosylase

disease_progression

DNA:loss of heterozygosity (human)

PMID:11260864 PMID:11866974

RGD:2317134 RGD:2317136

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

oxysterol binding protein 2

mRNA:increased expression:blood

NCBI chrNW_004936755:31,113...120,747
Ensembl chrNW_004936755:31,009...121,887

G

oxysterol binding protein like 7

mRNA:increased expression:blood

NCBI chrNW_004936490:13,491,704...13,506,742
Ensembl chrNW_004936490:13,491,544...13,506,768

G

pannexin 2

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936629:618,758...626,446
Ensembl chrNW_004936629:618,042...626,452

G

pro-apoptotic WT1 regulator

mRNA,protein:decreased expression:cholangiocyte:

NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057

G

polybromo 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052

G

paternally expressed 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936882:577,424...607,691
Ensembl chrNW_004936882:577,395...591,042

G

pescadillo ribosomal biogenesis factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936904:125,922...140,559
Ensembl chrNW_004936904:126,003...140,235

G

pirin

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936470:4,794,803...4,902,211
Ensembl chrNW_004936470:4,793,823...4,902,471

G

peptidylprolyl isomerase A

ameliorates

human cell line and construct in a mouse model

NCBI chrNW_004936478:19,669,727...19,673,355
Ensembl chrNW_004936478:19,669,506...19,673,398

G

protein phosphatase 3 catalytic subunit alpha

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

sexual_dimorphism

DNA:substitutions, insertion/deletions: (human)

NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346

G

protein kinase cAMP-activated catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753

G

protein kinase cAMP-activated catalytic subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636

G

proline rich and Gla domain 4

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936533:5,032,718...5,053,452
Ensembl chrNW_004936533:5,032,581...5,053,529

G

serine protease 56

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936525:4,568,854...4,574,332
Ensembl chrNW_004936525:4,568,802...4,574,396

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

PMID:23376645 PMID:27022031

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

prostaglandin-endoperoxide synthase 2

ClinVar Annotator: match by term: Cholangiocarcinoma

NCBI chrNW_004936481:3,821,564...3,828,086

G

Ras association domain family member 8

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936548:1,353,237...1,444,176
Ensembl chrNW_004936548:1,352,902...1,444,202

G

regenerating family member 1 alpha

susceptibility

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936556:4,873,331...4,875,608
Ensembl chrNW_004936556:4,873,331...4,875,608

G

ring finger protein 39

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936723:967,376...972,496
Ensembl chrNW_004936723:967,263...975,952

G

ring finger protein 43

exacerbates

CTD Direct Evidence: marker/mechanism
associated with opisthorchiasis;DNA:SNPs:multiple: (human)

NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828

G

roundabout guidance receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936505:5,544,011...6,747,417
Ensembl chrNW_004936505:5,548,164...6,094,225

G

RUNX family transcription factor 3

protein:decreased expression:bile duct

NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910

G

solute carrier family 4 member 4

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936598:3,391,587...3,713,629
Ensembl chrNW_004936598:3,391,575...3,713,635

G

solute carrier family 5 member 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:3,176,009...3,188,637
Ensembl chrNW_004936596:3,177,422...3,188,637

G

solute carrier family 7 member 5

disease_progression
treatment

PMID:24131658 PMID:25475870 PMID:28347255

RGD:151361214 RGD:151361287 RGD:151361294

NCBI chrNW_004936641:1,513,110...1,538,955

G

SMAD family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

suppressor of cytokine signaling 3

severity

protein:decreased expression:bile duct (human)

NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451

G

SRY-box transcription factor 17

severity

NCBI chrNW_004936496:1,248,582...1,251,406
Ensembl chrNW_004936496:1,248,577...1,251,430

G

SRY-box transcription factor 2

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613

G

transforming growth factor beta 1

disease_progression

protein:increased expression:pancreas

PMID:12632524 PMID:16083599

RGD:1299231 RGD:2325020

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

transforming growth factor beta receptor 2

mRNA:increased expression:bile duct

NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430

G

thrombospondin 1

disease_progression

DNA:hypermethylation (human)

PMID:11927969 PMID:12213730 PMID:16465407

RGD:2325024 RGD:2325026 RGD:2325027

NCBI chrNW_004936471:3,064,466...3,081,125
Ensembl chrNW_004936471:3,064,422...3,081,949

G

tenascin C

severity

NCBI chrNW_004936487:4,172,263...4,256,780
Ensembl chrNW_004936487:4,172,886...4,233,126

G

TNF alpha induced protein 3

severity

protein:increased expression:bile duct (human)

NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

PMID:16818635 PMID:22561520

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

transthyretin

protein:decreased expression:blood serum (human)

NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566

G

vascular endothelial growth factor A

ClinVar Annotator: match by term: Cholangiocarcinoma

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

WD repeat and HMG-box DNA binding protein 1

ameliorates

NCBI chrNW_004936697:129,821...184,238
Ensembl chrNW_004936697:130,105...183,576

G

Wnt family member 9A

disease_progression

mRNA:altered expression:liver (human)

NCBI chrNW_004936864:216,381...245,885
Ensembl chrNW_004936864:239,651...244,312

choriocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibroblast growth factor 8

protein:increased expression:testicular germ cell neoplasms

NCBI chrNW_004936600:4,004,847...4,010,626
Ensembl chrNW_004936600:4,004,824...4,010,689

G

insulin like growth factor 2

disease_progression

protein:increased expression:tumor:elevated IGF-II increased choriocarcinoma cell invasion via activation of INSR

NCBI chrNW_004936816:972,902...981,232
Ensembl chrNW_004936816:972,282...979,167

G

insulin receptor

disease_progression

protein:increased activity:tumor:IGF-II increased choriocarcinoma cell invasion via activation of INSR

NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668

G

platelet derived growth factor subunit B

mRNA:increased expression:mononuclear cytotrophoblast cell

NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573

G

platelet derived growth factor receptor beta

mRNA:increased expression:mononuclear cytotrophoblast cell

NCBI chrNW_004936504:4,762,251...4,799,789
Ensembl chrNW_004936504:4,762,184...4,799,829

G

TIMP metallopeptidase inhibitor 3

DNA, protein:hypermethylation, decreased expression:promoter, placenta

NCBI chrNW_004936492:6,996,627...7,046,137
Ensembl chrNW_004936492:6,996,613...7,046,190

chromophobe renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

baculoviral IAP repeat containing 5

exacerbates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

HNF1 homeobox A

ClinVar Annotator: match by term: Chromophobe renal cell carcinoma

PMID:9392505 PMID:9754819 PMID:10966642 PMID:11393552 PMID:15649945 More...

NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505

G

HNF1 homeobox B

ClinVar Annotator: match by term: Chromophobe renal cell carcinoma

PMID:15649945 PMID:16371430 PMID:25536396 PMID:25700310 PMID:25741868

NCBI chrNW_004936490:649,551...702,448
Ensembl chrNW_004936490:649,546...702,672

clear cell adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 apoptosis regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

chromobox 7

disease_progression

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

death domain associated protein

protein:increased expression:ovary:

NCBI chrNW_004936476:25,546,091...25,550,390
Ensembl chrNW_004936476:25,546,036...25,550,392

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

clear cell renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

atypical chemokine receptor 3

mRNA:increased expression:kidney:

NCBI chrNW_004936525:1,559,575...1,570,679

G

advanced glycosylation end-product specific receptor

mRNA:increased expression:renal cortex (human)

NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Clear cell carcinoma of kidney

PMID:8755918 PMID:9792409 PMID:10980530 PMID:18560558 PMID:19431188 More...

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

ATP synthase membrane subunit c locus 2

NCBI chrNW_004936512:10,908,915...10,918,445
Ensembl chrNW_004936512:10,908,881...10,918,445

G

ATP synthase peripheral stalk-membrane subunit b

NCBI chrNW_004936690:120,572...135,509

G

ATP synthase peripheral stalk subunit OSCP

NCBI chrNW_004936500:8,444,681...8,454,694
Ensembl chrNW_004936500:8,444,546...8,456,048

G

BRCA1 associated deubiquitinase 1

ClinVar Annotator: match by term: Clear cell carcinoma of kidney

PMID:25741868 PMID:28492532 PMID:35483881 PMID:35992853

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

BCL2 associated X, apoptosis regulator

mRNA, protein:increased expression:kidney

NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820

G

baculoviral IAP repeat containing 3

disease_progression

mRNA:increased expression:kidney (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

exacerbates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

baculoviral IAP repeat containing 6

ameliorates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936493:903,295...1,115,434
Ensembl chrNW_004936493:899,961...1,115,493

G

chromodomain helicase DNA binding protein 4

mRNA:decreased expression:kidney (human)

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Clear cell carcinoma of kidney

PMID:8755918 PMID:9792409 PMID:10980530 PMID:18560558 PMID:19431188 More...

NCBI chrNW_004936551:305,617...343,369
Ensembl chrNW_004936551:305,611...351,063

G

C-X-C motif chemokine ligand 12

mRNA:decreased expression:kidney:

NCBI chrNW_004936617:4,224,131...4,239,080
Ensembl chrNW_004936617:4,224,131...4,238,796

G

C-X-C motif chemokine receptor 4

mRNA:increased expression:kidney:

NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459

G

discoidin domain receptor tyrosine kinase 1

severity

mRNA:increased expression:kidney, lymph nodes (human)
mRNA, protein:decreased expression:kidney (human)

PMID:27020590 PMID:31018949

RGD:151347528 RGD:151347863

NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833

G

DNA methyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

DNA methyltransferase 3 alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610

G

egl-9 family hypoxia inducible factor 3

disease_progression

NCBI chrNW_004936494:8,240,272...8,267,487
Ensembl chrNW_004936494:8,238,858...8,267,606

G

endoglin

severity

protein:increased expression:tumor, vasculature (human)
protein:decreased expression:kidney, tumor (human)

PMID:16536758 PMID:22204709

RGD:7248775 RGD:7248780

NCBI chrNW_004936487:15,467,165...15,499,180
Ensembl chrNW_004936487:15,467,835...15,477,488

G

E1A binding protein p300

severity

mRNA:altered expression:kidney, tumor (human)
mRNA, protein:increased expression:kidney

PMID:23029358 PMID:28551630

RGD:15036804 RGD:7296925

NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138

G

coagulation factor II, thrombin

protein:increased expression:brain

NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650

G

fms related receptor tyrosine kinase 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936739:240,572...281,925
Ensembl chrNW_004936739:236,510...281,729

G

FTO alpha-ketoglutarate dependent dioxygenase

disease_progression
treatment

mRNA:decreased expression:kidney
mRNA:increased expression:kidney

PMID:30648791 PMID:32817424

RGD:329812005 RGD:329812006

NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588

G

GATA binding protein 1

disease_progression

NCBI chrNW_004936721:742,862...750,843
Ensembl chrNW_004936721:742,862...750,768

G

GATA binding protein 2

disease_progression

NCBI chrNW_004936798:406,258...414,785
Ensembl chrNW_004936798:406,258...414,931

G

glutathione S-transferase pi 1

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

HNF1 homeobox A

ClinVar Annotator: match by term: Clear cell carcinoma of kidney | ClinVar Annotator: match by term: Clear cell renal carcinoma

PMID:8866553 PMID:8945470 PMID:9032114 PMID:9045858 PMID:9075818 More...

NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505

G

insulin like growth factor 1 receptor

xenograph of human clear cell renal cancer cells in mouse

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

iron-sulfur cluster assembly enzyme

disease_progression

mRNA,protein:decreased expression:kidney (human)

NCBI chrNW_004936769:492,024...498,587
Ensembl chrNW_004936769:491,530...498,692

G

lysine acetyltransferase 8

mRNA, protein:decreased expression:kidney (human)

NCBI chrNW_004936501:13,475,676...13,487,617
Ensembl chrNW_004936501:13,474,735...13,489,341

G

mitogen-activated protein kinase kinase kinase 8

ameliorates
disease_progression

NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892

G

matrix metallopeptidase 12

NCBI chrNW_004936551:5,107,567...5,117,843
Ensembl chrNW_004936551:5,106,285...5,117,843

G

methylenetetrahydrofolate reductase

susceptibility
severity

DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human)

PMID:20039875 PMID:21489764

RGD:6893474 RGD:6893632

NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193

G

MYC proto-oncogene, bHLH transcription factor

severity

protein:increased expression:kidney (human)

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

8-oxoguanine DNA glycosylase

ClinVar Annotator: match by term: Clear cell carcinoma of kidney

PMID:9681819 PMID:10987279 PMID:12172214 PMID:19537786 PMID:21195604 More...

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

p21 (RAC1) activated kinase 4

disease_progression

NCBI chrNW_004936661:2,012,439...2,048,523

G

p21 (RAC1) activated kinase 6

disease_progression

NCBI chrNW_004936471:3,692,058...3,747,355
Ensembl chrNW_004936471:3,713,406...3,747,356

G

polybromo 1

ClinVar Annotator: match by term: Clear cell carcinoma of kidney

NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052

G

platelet derived growth factor subunit B

disease_progression

PMID:23879920 PMID:25766258

RGD:13504817 RGD:13506650

NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573

G

PML nuclear body scaffold

protein:decreased expression:kidney (human)

NCBI chrNW_004936471:33,135,186...33,173,218
Ensembl chrNW_004936471:33,135,164...33,177,666

G

pro-platelet basic protein

ameliorates
disease_progression

NCBI chrNW_004936598:1,719,501...1,720,890
Ensembl chrNW_004936598:1,719,480...1,720,911

G

SET domain containing 2, histone lysine methyltransferase

severity

DNA:mutations:multiple (human)
DNA:SNPs,loss of heterozygosity:multiple (human)

PMID:26864202 PMID:26891804

RGD:150429635 RGD:150429640

NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

mRNA,protein:decreased expression:kidney:

NCBI chrNW_004936619:1,276,239...1,308,945
Ensembl chrNW_004936619:1,275,362...1,308,913

G

serine and arginine rich splicing factor 1

mRNA:altered expression:kidney (human)

NCBI chrNW_004936490:5,055,258...5,059,118
Ensembl chrNW_004936490:5,055,253...5,059,116

G

serine and arginine rich splicing factor 2

mRNA:altered expression:kidney (human)

NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164

G

serine and arginine rich splicing factor 4

mRNA:altered expression:kidney (human)

NCBI chrNW_004936474:13,113,191...13,140,956
Ensembl chrNW_004936474:13,113,867...13,140,599

G

serine and arginine rich splicing factor 5

mRNA:altered expression:kidney (human)

NCBI chrNW_004936495:12,952,610...12,957,640
Ensembl chrNW_004936495:12,952,646...12,960,681

G

serine and arginine rich splicing factor 6

mRNA:altered expression:kidney (human)

NCBI chrNW_004936530:3,086,944...3,092,780
Ensembl chrNW_004936530:3,086,680...3,092,828

G

serine and arginine rich splicing factor 7

mRNA:altered expression:kidney (human)

NCBI chrNW_004936508:12,475,906...12,481,501
Ensembl chrNW_004936508:12,475,661...12,481,501

G

tumor protein p53

mRNA, protein:increased expression:kidney

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

X-linked inhibitor of apoptosis

ameliorates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

colon adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

disease_progression

mRNA:decreased expression:colon (human)
human cells in mouse model

NCBI chrNW_004936695:1,644,758...1,672,024
Ensembl chrNW_004936695:1,644,581...1,672,117

G

annexin A7

protein:decreased expression:colon

NCBI chrNW_004936521:5,639,193...5,671,369
Ensembl chrNW_004936521:5,651,719...5,671,050

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Colon adenocarcinoma

PMID:24033266 PMID:24728327 PMID:25741868 PMID:27978560 PMID:28492532

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

AT-rich interaction domain 1A

disease_progression

protein:decreased expression:colorectum (human)

NCBI chrNW_004936474:11,148,857...11,197,312

G

BCL2 associated X, apoptosis regulator

susceptibility

DNA:frameshift mutation: ;

NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820

G

BCL2 apoptosis regulator

treatment

human cells in mouse model

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

Bruton tyrosine kinase

mRNA:decreased expression:colon (human)

NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441

G

carbonic anhydrase 12

disease_progression

NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987

G

calcium voltage-gated channel subunit alpha1 D

disease_progression

protein:increased expression:colon (human)

NCBI chrNW_004936473:4,164,633...4,479,866
Ensembl chrNW_004936473:4,037,533...4,478,073

G

calreticulin

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

chromodomain helicase DNA binding protein 4

ameliorates

human cells in a mouse model

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

colony stimulating factor 1 receptor

ameliorates

mouse cell line in a mouse model
human cells in a mouse model

PMID:24898549 PMID:29436396 PMID:32304779

RGD:150524289 RGD:150524290 RGD:150524303

NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923

G

colony stimulating factor 2

treatment

NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864

G

catenin beta 1

DNA:mutation

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

death domain associated protein

protein:decreased expression:colon:

NCBI chrNW_004936476:25,546,091...25,550,390
Ensembl chrNW_004936476:25,546,036...25,550,392

G

eukaryotic translation elongation factor 2

protein:increased expression:colon(human)

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

ferrochelatase

mRNA:decreased expression:colon

NCBI chrNW_004936497:6,755,626...6,788,568
Ensembl chrNW_004936497:6,755,553...6,790,944

G

FOS like 1, AP-1 transcription factor subunit

protein:increased expression:colon (human)

NCBI chrNW_004936599:3,642,504...3,649,294
Ensembl chrNW_004936599:3,642,504...3,648,417

G

FOS like 2, AP-1 transcription factor subunit

protein:increased expression:colon (human)

NCBI chrNW_004936493:4,308,683...4,327,102
Ensembl chrNW_004936493:4,304,395...4,327,179

G

forkhead box A1

mRNA:decreased expression:colon

NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224

G

GATA binding protein 1

NCBI chrNW_004936721:742,862...750,843
Ensembl chrNW_004936721:742,862...750,768

G

high mobility group box 1

NCBI chrNW_004936472:25,236,728...25,246,585
Ensembl chrNW_004936472:25,236,728...25,246,580

G

interleukin 21

treatment

NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883

G

Janus kinase 2

ameliorates
treatment

human cells in mouse model
Human cell in mouse model

PMID:22050790 PMID:32504672

RGD:125097526 RGD:127285665

NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867

G

lysine demethylase 6A

DNA:hypermethylation

NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163

G

signal transducer and activator of transcription 5B

DNA:SNPs:introns: (rs6503691, rs7218653) (human)

NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

mRNA:increased expression:colonic mucosa (human)
mRNA:increased expression:colon (human)

PMID:27793774 PMID:33791222

RGD:151665173 RGD:151665790

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

G

lysyl oxidase

ameliorates

NCBI chrNW_004936575:2,526,067...2,533,996
Ensembl chrNW_004936575:2,524,342...2,533,559

G

mitogen-activated protein kinase kinase 7

human cell line and gene in a mouse model

NCBI chrNW_004936588:4,882,191...4,891,807
Ensembl chrNW_004936588:4,882,184...4,892,071

G

mitogen-activated protein kinase 1

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

mitogen-activated protein kinase 3

NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180

G

O-6-methylguanine-DNA methyltransferase

mRNA:decreased expression:colon (rat)

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

matrix metallopeptidase 2

protein:increased expression:colon (human)

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

protein:increased expression:colon (human)

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

mutS homolog 6

ClinVar Annotator: match by term: Colon adenocarcinoma

NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787

G

MYD88 innate immune signal transduction adaptor

exacerbates

human cell line in a mouse model

NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372

G

NLR family apoptosis inhibitory protein

exacerbates

mRNA:increased expression:colon (human)

NCBI chrNW_004936549:5,000,526...5,069,110

G

nitric oxide synthase 2

protein:increased expression:colon (human)

NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051

G

proprotein convertase subtilisin/kexin type 5

mRNA:decreased expression:colon:

NCBI chrNW_004936503:11,466,955...11,896,887
Ensembl chrNW_004936503:11,466,950...11,896,887

G

phosphoribosylformylglycinamidine synthase

NCBI chrNW_004936595:1,483,688...1,499,716
Ensembl chrNW_004936595:1,483,689...1,501,364

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

DNA:mutation

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phosphoinositide-3-kinase regulatory subunit 3

treatment

NCBI chrNW_004936474:27,095,125...27,171,416
Ensembl chrNW_004936474:27,095,100...27,171,252

G

Rac family small GTPase 1

treatment

mRNA:alternative form

PMID:10597294 PMID:19561401

RGD:13432049 RGD:13432051

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

RAD54 like

ClinVar Annotator: match by term: Colon adenocarcinoma

NCBI chrNW_004936474:27,276,570...27,316,427
Ensembl chrNW_004936474:27,280,573...27,316,428

G

ribonuclease L

severity

NCBI chrNW_004936481:7,165,400...7,177,342
Ensembl chrNW_004936481:7,165,353...7,177,538

G

ribonuclease T2

human cells in mouse model

NCBI chrNW_004936489:16,540,558...16,555,669
Ensembl chrNW_004936489:16,540,562...16,555,670

G

solute carrier family 67 member 1

ameliorates

mRNA:decreased expression:colorectum (human)

NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345

G

structural maintenance of chromosomes 2

severity

human cell line in a mouse model

NCBI chrNW_004936793:909,663...958,883
Ensembl chrNW_004936793:910,654...958,811

G

SRC proto-oncogene, non-receptor tyrosine kinase

ameliorates

NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483

G

serine and arginine rich splicing factor 4

mRNA:decreased expression:colon mucosa (human)

NCBI chrNW_004936474:13,113,191...13,140,956
Ensembl chrNW_004936474:13,113,867...13,140,599

G

serine and arginine rich splicing factor 5

mRNA:decreased expression:colon mucosa (human)

NCBI chrNW_004936495:12,952,610...12,957,640
Ensembl chrNW_004936495:12,952,646...12,960,681

G

serine and arginine rich splicing factor 6

mRNA:decreased expression:colon mucosa (human)

NCBI chrNW_004936530:3,086,944...3,092,780
Ensembl chrNW_004936530:3,086,680...3,092,828

G

signal transducer and activator of transcription 1

DNA:SNPs:introns: (rs2280232, rs4327257) (human)

NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756

G

signal transducer and activator of transcription 3

treatment

human cells in mouse model
DNA:SNPs:introns: (rs12949918, rs6503695) (human)

PMID:22121102 PMID:32504672

RGD:125097526 RGD:153323313

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

G

signal transducer and activator of transcription 6

DNA:SNP:3' utr: (rs324015) (human)

NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157

G

telomerase reverse transcriptase

treatment

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

tet methylcytosine dioxygenase 2

mRNA:increased expression:colorectum, Cancer Stem-like Cells (human)

NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615

G

transforming growth factor beta 1

disease_progression

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

tumor protein p73

mRNA:increased expression:colon (human)

NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464

G

ubiquitin protein ligase E3 component n-recognin 5

ameliorates
severity

human cell line in a mouse model

PMID:28856538 PMID:29296225

RGD:151665195 RGD:151665199

NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134

G

vascular endothelial growth factor C

mRNA:increased expression:colon

NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559

colorectal adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1

susceptibility

DNA:polymorphism: :3435C>T (human)

NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427

G

actin related protein 2/3 complex subunit 2

mRNA:decreased expression:colonic mucosa (human)

NCBI chrNW_004936569:758,358...786,995
Ensembl chrNW_004936569:758,199...786,760

G

BCL2 like 1

protein:increased expression:colonic mucosa (human)

NCBI chrNW_004936485:18,654,046...18,707,324

G

baculoviral IAP repeat containing 7

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

BLOC-1 related complex subunit 5

susceptibility

DNA:SNP:3'utr: (rs3803098) A>G (human)

NCBI chrNW_004936587:4,806,537...4,906,301
Ensembl chrNW_004936587:4,806,113...4,906,411

G

B-Raf proto-oncogene, serine/threonine kinase

disease_progression

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

bromodomain containing 8

disease_progression

NCBI chrNW_004936531:7,333,974...7,361,855
Ensembl chrNW_004936531:7,333,907...7,362,114

G

carbonic anhydrase 12

severity

NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987

G

coiled-coil domain containing 17

susceptibility

DNA:SNP:3'utr: (rs2275085) T>C (human)

NCBI chrNW_004936474:26,744,393...26,748,173
Ensembl chrNW_004936474:26,744,603...26,748,165

G

CD44 molecule (IN blood group)

disease_progression

mRNA, protein:splice variant, increased expression:large intestine

NCBI chrNW_004936533:2,949,026...3,033,166

G

DNA methyltransferase 3 beta

susceptibility

DNA:SNP: : 39179G>T(human)

NCBI chrNW_004936485:19,547,836...19,570,716

G

docking protein 3

susceptibility

DNA:SNP:3'utr: (rs2279398) (human)

NCBI chrNW_004936597:1,781,129...1,785,998
Ensembl chrNW_004936597:1,781,306...1,785,959

G

empty spiracles homeobox 2

exacerbates

mRNA:decreased expression:colorectal mucosa (human)

NCBI chrNW_004936486:7,313,689...7,319,971
Ensembl chrNW_004936486:7,313,190...7,319,995

G

erb-b2 receptor tyrosine kinase 3

severity

NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297

G

ERCC excision repair 6, chromatin remodeling factor

mRNA:decreased expression:colorectum (human)

NCBI chrNW_004936728:706,499...843,447
Ensembl chrNW_004936728:761,804...844,690

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

disease_progression

DNA:SNP: rs3757441 (human)

NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939

G

family with sequence similarity 151 member A

susceptibility

DNA:SNP:3'utr: (rs11206394) G>C (human)

NCBI chrNW_004936522:6,623,107...6,637,532

G

fibroblast growth factor receptor 2

treatment

human cell line in a mouse model

NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019

G

fms related receptor tyrosine kinase 3

severity

DNA:polymorphisms:multiple

NCBI chrNW_004936472:23,169,967...23,239,178
Ensembl chrNW_004936472:23,170,470...23,256,904

G

Fos proto-oncogene, AP-1 transcription factor subunit

NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122

G

GATA binding protein 6

severity

human cells in a mouse model

NCBI chrNW_004936550:1,814,336...1,844,399
Ensembl chrNW_004936550:1,814,336...1,844,399

G

gap junction protein beta 3

susceptibility

DNA:SNP:3'utr: (rs9118) C>G (human)

NCBI chrNW_004936474:17,427,255...17,431,368
Ensembl chrNW_004936474:17,429,926...17,430,729

G

glutathione peroxidase 4

susceptibility

DNA:SNP:3' utr:c.718T>C (human)

NCBI chrNW_004936588:506,101...508,469
Ensembl chrNW_004936588:506,147...508,101

G

glycogen synthase kinase 3 beta

NCBI chrNW_004936536:6,730,070...6,893,818
Ensembl chrNW_004936536:6,730,062...6,894,303

G

hippocalcin

severity

mRNA, protein:increased expression:colon carcinoma (human)

NCBI chrNW_004936474:15,786,171...15,794,830
Ensembl chrNW_004936474:15,785,879...15,798,740

G

immediate early response 2

disease_progression

protein:increased expression:colon (human)

NCBI chrNW_004936659:2,176,962...2,179,900
Ensembl chrNW_004936659:2,178,312...2,178,983

G

interleukin 16

susceptibility

DNA:SNP:3'utr: (rs1131445) T>C (human)

NCBI chrNW_004936483:19,417,580...19,512,654
Ensembl chrNW_004936483:19,418,086...19,512,639

G

Jun proto-oncogene, AP-1 transcription factor subunit

NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350

G

JunB proto-oncogene, AP-1 transcription factor subunit

protein:increased expression:colorectal mucosa (human)

NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123

G

potassium voltage-gated channel subfamily H member 1

severity

DNA:amplification: (human)

NCBI chrNW_004936557:2,133,596...2,493,170
Ensembl chrNW_004936557:2,133,564...2,493,155

G

kinase insert domain receptor

treatment
severity

protein:altered phosphorylation:colon

PMID:25372416 PMID:26325365

RGD:11529678 RGD:126848811

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

lysine methyltransferase 2B

human gene in a mouse model

NCBI chrNW_004936570:583,616...605,846
Ensembl chrNW_004936570:583,616...605,603

G

signal transducer and activator of transcription 5B

disease_progression
ameliorates

protein:increased expression:colorectum (human)
human cells in a mouse model

PMID:21826656 PMID:23733954

RGD:11076784 RGD:153298931

NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

susceptibility

DNA:SNPs:enhancers: (rs6013897, rs158552, rs17217119) (human)

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

G

mitogen-activated protein kinase 1

treatment

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

mitogen-activated protein kinase 3

treatment

NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180

G

mitogen-activated protein kinase 8

NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907

G

mutS homolog 2

disease_progression

NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356

G

MYD88 innate immune signal transduction adaptor

exacerbates

RNA:decreased expression:colon (human)

NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372

G

nuclear receptor coactivator 2

protein:increased expression:colorectal mucosa (human)

NCBI chrNW_004936496:14,844,923...15,102,922
Ensembl chrNW_004936496:14,844,855...15,016,454

G

nucleotide binding oligomerization domain containing 2

susceptibility

DNA:SNP:3'utr: (rs3135499) C>A (human)

NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982

G

proprotein convertase subtilisin/kexin type 4

susceptibility

DNA:SNP:3'utr: (rs1047854) C>T (human)

NCBI chrNW_004936588:793,615...800,038
Ensembl chrNW_004936588:794,227...799,663

G

RAB24, member RAS oncogene family

susceptibility

DNA:SNP:3'utr: (rs1128287) C>A (human)

NCBI chrNW_004936597:1,578,529...1,580,787
Ensembl chrNW_004936597:1,578,322...1,580,775

G

Rac family small GTPase 1

disease_progression

mRNA, protein:increased expression:colorectum (human)

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

Raf-1 proto-oncogene, serine/threonine kinase

NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096

G

regulator of G protein signaling 5

susceptibility

DNA:SNP:3'utr: (rs15049) C>A (human)

NCBI chrNW_004936481:21,421,319...21,483,108
Ensembl chrNW_004936481:21,421,277...21,483,132

G

RPTOR independent companion of MTOR complex 2

disease_progression

protein:increased expression:colon (human)

NCBI chrNW_004936518:3,198,312...3,314,393
Ensembl chrNW_004936518:3,198,337...3,310,000

G

ribonuclease T2

human cells in mouse model

NCBI chrNW_004936489:16,540,558...16,555,669
Ensembl chrNW_004936489:16,540,562...16,555,670

G

radial spoke head component 1

susceptibility

DNA:SNP:3'utr: (rs2839531) T>C (human)

NCBI chrNW_004936500:1,402,289...1,423,398
Ensembl chrNW_004936500:1,402,219...1,423,509

G

solute carrier family 7 member 5

disease_progression

NCBI chrNW_004936641:1,513,110...1,538,955

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

disease_progression

protein:decreased expression:colon, nucleus

NCBI chrNW_004936619:1,276,239...1,308,945
Ensembl chrNW_004936619:1,275,362...1,308,913

G

suppressor of cytokine signaling 1

no_association

NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165

G

signaling receptor and transporter of retinol STRA6

mRNA:increased expression:colorectum (human)

NCBI chrNW_004936471:33,224,174...33,245,076
Ensembl chrNW_004936471:33,224,859...33,245,030

G

tumor protein p53

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor protein p73

exacerbates

protein:increased expression:colon (human)

NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464

G

tyrosylprotein sulfotransferase 1

susceptibility

DNA:SNP:3'utr: (rs3757417) G>T (human)

NCBI chrNW_004936543:7,497,431...7,592,790
Ensembl chrNW_004936543:7,497,424...7,565,483

G

thymidylate synthetase

protein:increased activity:colon (rat)

NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840

G

UTP23 small subunit processome component

susceptibility

DNA:missense mutation:cds:p.P215Q (rs16888728) (human)

NCBI chrNW_004936470:29,489,354...29,495,171
Ensembl chrNW_004936470:29,486,977...29,495,222

G

X-ray repair cross complementing 1

treatment

associated with Neoplasm Metastasis; DNA:missense mutation:cds: p.R399Q, c.1196G>A (human)

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

cutaneous Paget's disease

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

severity

DNA:mutations:multiple:

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

Ductal Carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCAR1 scaffold protein, Cas family member

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:23,994,130...24,032,829
Ensembl chrNW_004936475:23,992,193...24,033,031

G

carbonic anhydrase 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433

G

cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

forkhead box A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224

G

hypoxia inducible factor 1 subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

heat shock protein 90 alpha family class A member 1

NCBI chrNW_004936835:316,767...321,999
Ensembl chrNW_004936835:316,767...321,990

G

MYC proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

solute carrier family 2 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713

G

speckle type BTB/POZ protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

ductal carcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiogenin

protein:increased expression:breast

NCBI chrNW_004936880:39,372...40,070

G

annexin A1

protein:decreased expression:mammary gland

NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413

G

androgen receptor

NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932

G

amphiregulin

protein:increased expression:breast

NCBI chrNW_004936598:1,276,599...1,283,612
Ensembl chrNW_004936598:1,274,565...1,283,746

G

BCL2 apoptosis regulator

disease_progression

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

baculoviral IAP repeat containing 5

disease_progression

protein:increased expression:breast

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

BCL2 interacting protein 3

NCBI chrNW_004936486:18,449,371...18,460,435
Ensembl chrNW_004936486:18,448,494...18,455,927

G

BRCA1 DNA repair associated

treatment

NCBI chrNW_004936490:17,735,444...17,801,456

G

BRCA2 DNA repair associated

treatment
onset

DNA:missense mutation: :5972C>T

PMID:16280055 PMID:25861310

RGD:127284854 RGD:2289048

NCBI chrNW_004936472:26,945,659...27,017,693

G

carbonic anhydrase 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433

G

caspase 6

protein:increased expression:breast

NCBI chrNW_004936563:912,502...920,025
Ensembl chrNW_004936563:911,304...919,119

G

cyclin D1

protein:decreased expression:breast

Ensembl chrNW_004936599:973,838...983,316

G

cyclin D2

DNA:hypermethylation:promoter, breast

NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810

G

cyclin dependent kinase inhibitor 1A

disease_progression

protein:increased expression:breast

NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182

G

erb-b2 receptor tyrosine kinase 2

disease_progression

protein:increased expression:breast

PMID:15788662 PMID:17119686

RGD:2289931 RGD:2289981

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

erb-b2 receptor tyrosine kinase 3

NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297

G

erb-b2 receptor tyrosine kinase 4

disease_progression

NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035

G

fms related receptor tyrosine kinase 1

associated with Carcinoma, Ductal, Breast

NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041

G

FOS like 1, AP-1 transcription factor subunit

mRNA, protein:increased expression:breast

NCBI chrNW_004936599:3,642,504...3,649,294
Ensembl chrNW_004936599:3,642,504...3,648,417

G

hypoxia inducible factor 1 subunit alpha

CTD Direct Evidence: marker/mechanism
protein:altered localization:nucleus

PMID:16080559 PMID:20526721

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

homeobox B13

DNA:hypermethylation

NCBI chrNW_004936490:12,688,572...12,690,908
Ensembl chrNW_004936490:12,688,559...12,690,908

G

lactate dehydrogenase B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936548:5,224,905...5,244,708
Ensembl chrNW_004936548:5,227,666...5,244,525

G

kallikrein-10

disease_progression

mRNA:decreased expression:breast

NCBI chrNW_004936889:663,114...666,067
Ensembl chrNW_004936889:663,573...667,519

G

matrix metallopeptidase 2

protein:increased expression:breast

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

protein:increased expression:breast

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

notch receptor 4

NCBI chrNW_004936727:1,386,842...1,409,823

G

p21 (RAC1) activated kinase 2

NCBI chrNW_004936784:1,351,034...1,391,992
Ensembl chrNW_004936784:1,351,039...1,391,992

G

progesterone receptor

disease_progression

NCBI chrNW_004936551:6,498,553...6,573,212
Ensembl chrNW_004936551:6,498,553...6,573,222

G

protein kinase C alpha

protein:decreased expression:breast

NCBI chrNW_004936541:6,231,604...6,488,201
Ensembl chrNW_004936541:6,233,110...6,488,052

G

prostaglandin E synthase

protein:increased expression:breast

NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922

G

prostaglandin-endoperoxide synthase 2

disease_progression

mRNA, protein:decreased expression:breast

PMID:18199541 PMID:18237383

RGD:2300199 RGD:2300203

NCBI chrNW_004936481:3,821,564...3,828,086

G

protein tyrosine kinase 2

protein:increased expression:breast

NCBI chrNW_004936470:10,379,855...10,578,531
Ensembl chrNW_004936470:10,379,872...10,578,543

G

RB transcriptional corepressor 1

mRNA, protein:decreased expression:breast

NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846

G

RELA proto-oncogene, NF-kB subunit

DNA:amplification

NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813

G

solute carrier family 2 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713

G

suppressor of cytokine signaling 1

mRNA:increased expression:breast

NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165

G

suppressor of cytokine signaling 2

mRNA:increased expression:breast

NCBI chrNW_004936507:10,013,982...10,015,480
Ensembl chrNW_004936507:10,012,101...10,014,456

G

suppressor of cytokine signaling 3

mRNA:increased expression:breast

NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451

G

SRC proto-oncogene, non-receptor tyrosine kinase

severity

protein:increased activity:breast

NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483

G

ST14 transmembrane serine protease matriptase

protein:increased expression:breast

NCBI chrNW_004936572:2,137,820...2,182,674
Ensembl chrNW_004936572:2,137,332...2,182,742

G

telomerase reverse transcriptase

mRNA:decreased expression:breast

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

TIMP metallopeptidase inhibitor 2

protein:increased expression:breast

NCBI chrNW_004936594:3,232,433...3,244,241
Ensembl chrNW_004936594:3,232,355...3,244,241

G

TIMP metallopeptidase inhibitor 4

protein:increased expression:breast

NCBI chrNW_004936602:1,488,993...1,496,108
Ensembl chrNW_004936602:1,489,545...1,495,478

G

DNA topoisomerase II alpha

severity

protein:increased expression:breast

NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978

G

tumor protein p53

ClinVar Annotator: match by term: Ductal breast carcinoma in situ

PMID:1565143 PMID:1683921 PMID:1978757 PMID:7887414 PMID:8023157 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

thymidine phosphorylase

NCBI chrNW_004936629:315,609...320,356
Ensembl chrNW_004936629:315,610...319,076

G

vascular endothelial growth factor A

protein:increased expression:breast

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

duodenal gastrinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

menin 1

associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: :

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

duodenum adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Duodenal adenocarcinoma

PMID:24033266 PMID:25741868 PMID:26530882 PMID:28195569 PMID:28492532 More...

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

eccrine porocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

lysine methyltransferase 2D

ClinVar Annotator: match by term: Eccrine porocarcinoma

NCBI chrNW_004936512:6,819,240...6,860,852
Ensembl chrNW_004936512:6,822,057...6,854,451

G

MRE11 homolog, double strand break repair nuclease

ClinVar Annotator: match by term: Eccrine porocarcinoma

NCBI chrNW_004936674:466,495...528,072
Ensembl chrNW_004936674:466,456...530,317

G

T-box transcription factor 3

ClinVar Annotator: match by term: Eccrine porocarcinoma

NCBI chrNW_004936558:7,230,361...7,243,651
Ensembl chrNW_004936558:7,230,668...7,244,361

endometrial adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiopoietin 1

protein:increased expression:endometrium epithelium

NCBI chrNW_004936470:37,105,469...37,328,183
Ensembl chrNW_004936470:37,105,466...37,328,190

G

angiopoietin 2

protein:increased expression:endometrium epithelium

NCBI chrNW_004936615:4,472,261...4,524,537
Ensembl chrNW_004936615:4,472,247...4,524,556

G

AT-rich interaction domain 1A

treatment

human cell in mouse model

NCBI chrNW_004936474:11,148,857...11,197,312

G

axin 2

NCBI chrNW_004936541:7,155,963...7,242,466
Ensembl chrNW_004936541:7,211,985...7,242,470

G

Bet1 golgi vesicular membrane trafficking protein like

disease_progression

NCBI chrNW_004936888:42,646...56,589
Ensembl chrNW_004936888:52,019...56,776

G

CD55 molecule (Cromer blood group)

NCBI chrNW_004936557:5,344,373...5,364,234

G

estrogen receptor binding site associated antigen 9

protein:increased expression:endometrium

NCBI chrNW_004936470:35,449,920...35,473,635
Ensembl chrNW_004936470:35,450,292...35,473,110

G

forkhead box O3

severity

associated with Obesity;protein:decreased expression:endometrium (human)

NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837

G

glutathione peroxidase 3

mRNA:decreased expression:endometrium (rat)

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

interferon regulatory factor 1

DNA:deletions (rat)

NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636

G

Jun proto-oncogene, AP-1 transcription factor subunit

no_association

protein, mRNA::endometrial epithelium and stroma:no correlation between expression and type of tissue or cancer stage or grade

NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350

G

KRAS proto-oncogene, GTPase

DNA:point mutation:CDS:p.G12D, p.G12S, p.Q61H (rat)

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

mitogen-activated protein kinase 1

treatment

protein:decreased phosphorylation:endometrium (human)
human tumor in a mouse model

PMID:14760076 PMID:23402905

RGD:13703125 RGD:13703137

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

mitogen-activated protein kinase 3

treatment

human tumor in a mouse model
protein:decreased phosphorylation:endometrium (human)

PMID:14760076 PMID:23402905

RGD:13703125 RGD:13703137

NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180

G

programmed cell death 10

disease_progression

protein:increased expression:endometrium (human)

NCBI chrNW_004936593:4,650,624...4,693,387
Ensembl chrNW_004936593:4,651,114...4,692,534

G

phosphoinositide-3-kinase regulatory subunit 1

DNA:mutations:multiple (human)

NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537

G

phosphatase and tensin homolog

ameliorates

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

prostaglandin E synthase

protein:increased expression:endometrium

NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922

G

ribonucleotide reductase regulatory subunit M2

DNA:amplification (rat)

NCBI chrNW_004936532:6,348,041...6,390,144

G

transforming growth factor beta receptor 3

mRNA:decreased expression:endometrium

NCBI chrNW_004936537:7,154,125...7,340,218
Ensembl chrNW_004936537:7,175,516...7,336,895

G

tumor protein p53

disease_progression

DNA:missense mutations
protein:increased expression:endometrium

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor susceptibility 101

mRNA:alternative forms

NCBI chrNW_004936590:61,352...62,037

endometrial serous adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Uterine corpus serous adenocarcinoma

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

BRCA2 DNA repair associated

susceptibility

DNA:deletion: :6174delT

NCBI chrNW_004936472:26,945,659...27,017,693

G

mutS homolog 6

ClinVar Annotator: match by term: Papillary carcinoma of the corpus uteri

PMID:18269114 PMID:21642682 PMID:24362816 PMID:25741868 PMID:28492532 More...

NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787

esophagus adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

onset

DNA:SNP:3'utr: (rs4740363) (human)

NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669

G

AT-rich interaction domain 1A

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:23525077 PMID:31906887

NCBI chrNW_004936474:11,148,857...11,197,312

G

BARX homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004937000:88,529...96,794
Ensembl chrNW_004937000:88,529...92,147

G

BCL2 apoptosis regulator

onset

DNA:SNPs:3'utr: (rs720321, rs17757541) (human)

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

beclin 1

NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151

G

baculoviral IAP repeat containing 3

treatment

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

caspase 8

onset

DNA:SNP:5'utr: (rs1035142) (human)

NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922

G

cell division cycle 5 like

disease_progression

protein:increased expression:esophageal mucosa (human)

NCBI chrNW_004936476:15,647,470...15,698,095
Ensembl chrNW_004936476:15,648,678...15,698,106

G

CREB regulated transcription coactivator 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:2,551,621...2,625,327
Ensembl chrNW_004936596:2,551,506...2,625,327

G

dedicator of cytokinesis 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936609:4,695,202...5,099,038
Ensembl chrNW_004936609:4,695,628...5,099,038

G

engulfment and cell motility 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:12,308,255...12,754,957
Ensembl chrNW_004936478:12,306,450...12,754,963

G

empty spiracles homeobox 2

protein:decreased expression:esophagus (human)

NCBI chrNW_004936486:7,313,689...7,319,971
Ensembl chrNW_004936486:7,313,190...7,319,995

G

ERCC excision repair 1, endonuclease non-catalytic subunit

susceptibility

DNA:snps:cds, 3' utr:c.354C>T, c.8092C>A (human)

NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745

G

Fas cell surface death receptor

associated with Barrett Esophagus;protein:increased expression:esophageal mucosa (human)

NCBI chrNW_004936735:209,369...234,582

G

forkhead box A1

protein:increased expression:esophagus

NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224

G

forkhead box P1

CTD Direct Evidence: marker/mechanism
DNA:snps:intron, enhancer:g.70959438A>G, g.70879779A>C (rs9837992, rs2687201) (human)

PMID:24121790 PMID:26383589

NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324

G

ghrelin and obestatin prepropeptide

onset

DNA:SNP:5'utr: (rs696217) (human)

NCBI chrNW_004936602:3,037,862...3,044,863
Ensembl chrNW_004936602:3,038,549...3,042,506

G

glutathione peroxidase 3

susceptibility

DNA:SNPs:intron: (rs4958872, rs3792797) (human)

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

growth factor receptor bound protein 7

treatment
exacerbates

human cells in a mouse model

PMID:31809243 PMID:32737994

RGD:151347656 RGD:151347659

NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337

G

kinase insert domain receptor

onset

DNA:SNP:5'utr: (rs11941492) (human)

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

aromatase

onset

DNA:SNP:5'utr: (rs2445762) (human)

NCBI chrNW_004936471:13,107,603...13,136,910
Ensembl chrNW_004936471:13,107,603...13,136,910

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

treatment

mRNA:increased expression:esophagus (human)

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

G

matrix metallopeptidase 1

susceptibility

DNA:insertion:promoter:g.-1607insG rs1799750 (human)

NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857

G

matrix metallopeptidase 12

DNA:snp:promoter:g.-82A>G rs2276109 (human)

NCBI chrNW_004936551:5,107,567...5,117,843
Ensembl chrNW_004936551:5,106,285...5,117,843

G

matrix metallopeptidase 14

onset

DNA:SNP:5'utr: (rs2236302) (human)

NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611

G

matrix metallopeptidase 9

protein:increased expression:esophagus

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

neural EGFL like 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936654:1,591,016...2,392,496
Ensembl chrNW_004936654:1,591,847...2,394,692

G

nitric oxide synthase 3

onset

DNA:SNP:3'utr: (rs2070744) (human)

NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

prostaglandin-endoperoxide synthase 1

mRNA,protein:increased expression:Esophagus

NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823

G

prostaglandin-endoperoxide synthase 2

disease_progression

CTD Direct Evidence: marker/mechanism
protein: increased expression: esophagus

PMID:12055587 PMID:12507933

NCBI chrNW_004936481:3,821,564...3,828,086

G

solute carrier family 67 member 1

disease_progression

DNA:hypermethylation: (human)

NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345

G

SMAD family member 4

CTD Direct Evidence: marker/mechanism

PMID:23525077 PMID:24952744

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

smoothened, frizzled class receptor

treatment

NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281

G

superoxide dismutase 2

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

spartin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:30,467,975...30,525,880
Ensembl chrNW_004936472:30,467,964...30,504,624

G

toll like receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

vitamin D receptor

susceptibility
disease_progression

DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human)

PMID:24951052 PMID:25910066

RGD:11055189 RGD:13432070

NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109

extrahepatic bile duct adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 associated deubiquitinase 1

disease_progression

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

polybromo 1

disease_progression

NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052

G

Rac family small GTPase 1

protein:increased expression:mucosa (human)

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

solute carrier family 7 member 5

disease_progression

NCBI chrNW_004936641:1,513,110...1,538,955

extrahepatic bile duct carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

polycystin 1, transient receptor potential channel interacting

ClinVar Annotator: match by term: Extrahepatic bile duct cancer

NCBI chrNW_004936694:1,923,383...1,958,160
Ensembl chrNW_004936694:1,930,621...1,957,179

G

DNA polymerase delta 1, catalytic subunit

ClinVar Annotator: match by term: Extrahepatic bile duct cancer

PMID:25741868 PMID:26467025 PMID:28492532

NCBI chrNW_004936889:231,373...250,985
Ensembl chrNW_004936889:231,373...250,987
Ensembl chrNW_004936889:231,373...250,987

G

exportin 1

disease_progression

protein:increased expression:extrahepatic bile duct (human)

NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343

fibrolamellar carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

carbonic anhydrase 12

mRNA:increased expression:liver

NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987

G

catenin beta 1

protein:increased tyrosine phosphorylation:exon:

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

fibroblast growth factor receptor 1

protein:increased expression:liver:

NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508

G

protein kinase cAMP-activated catalytic subunit alpha

mRNA,protein:increased expression:liver (human)

NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753

follicular thyroid carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

KRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR

PMID:1654209 PMID:6587382 PMID:12727991 PMID:14508525 PMID:18633438 More...

NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590

G

protein kinase cAMP-dependent type I regulatory subunit alpha

OMIM:188470

NCBI chrNW_004936541:7,845,876...7,863,677
Ensembl chrNW_004936541:7,845,676...7,863,709

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR

PMID:24033266 PMID:24055113 PMID:25741868 PMID:25980754 PMID:28492532 More...

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

SLIT-ROBO Rho GTPase activating protein 1

ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR

NCBI chrNW_004936545:2,277,449...2,557,330
Ensembl chrNW_004936545:2,278,290...2,552,552

G

thyroid hormone receptor beta

CTD Direct Evidence: marker/mechanism
OMIM:188470

NCBI chrNW_004936473:15,766,214...15,986,389
Ensembl chrNW_004936473:15,770,146...15,986,561

gallbladder adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin dependent kinase 1

protein:increased expression:gallbladder

NCBI chrNW_004936614:2,300,682...2,313,611
Ensembl chrNW_004936614:2,300,513...2,313,624

G

discoidin domain receptor tyrosine kinase 2

disease_progression

NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139

G

angiotensin-converting enzyme

DNA:polymorphism: :rs4646994 (human)

NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177

gastric adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ALX homeobox 4

severity

NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000

G

adhesion molecule with Ig like domain 2

mRNA:increased expression:serosa of stomach (human)

NCBI chrNW_004936512:5,157,076...5,160,251
Ensembl chrNW_004936512:5,157,175...5,159,818

G

apolipoprotein C1

protein:decreased expression:serum

NCBI chrNW_004936706:1,519,248...1,520,102

G

apolipoprotein C3

disease_progression

protein:decreased expression:serum

PMID:21267442 PMID:27002935

RGD:153344621 RGD:153350083

NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603

G

AT-rich interaction domain 1A

disease_progression
exacerbates
severity

protein:decreased expression:stomach (human)
mRNA, protein:decreased expression:mucosa of stomach (human)
mRNA:decreased expression:mucosa of stomach (human)

PMID:22808142 PMID:24293408 PMID:25717252

RGD:125097488 RGD:125097521 RGD:126848753

NCBI chrNW_004936474:11,148,857...11,197,312

G

baculoviral IAP repeat containing 2

exacerbates

mRNA:increased expression:stomach (human)

NCBI chrNW_004936551:5,515,904...5,535,864

G

baculoviral IAP repeat containing 3

disease_progression

mRNA:increased expression:stomach (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 7

exacerbates

mRNA:increased expression:stomach (human)

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Adenocarcinoma of stomach

PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More...

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

calreticulin

ameliorates

human cell line and construct in a mouse model

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

catalase

protein:decreased expression:blood serum (human)

NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422

G

CD44 molecule (IN blood group)

disease_progression

mRNA, protein:splice variant, increased expression:stomach

NCBI chrNW_004936533:2,949,026...3,033,166

G

cell division cycle 73

exacerbates

protein:decreased expression:stomach (human)

NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277

G

cadherin 1

severity

mRNA:decreased expression:mucosa of stomach (human)
ClinVar Annotator: match by term: Adenocarcinoma of stomach

PMID:10896919 PMID:11968083 PMID:12588804 PMID:12944922 PMID:14500541 More...

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

cyclin dependent kinase 12

exacerbates

protein:increased expression:stomach (human)

NCBI chrNW_004936490:14,674,783...14,759,433
Ensembl chrNW_004936490:14,674,800...14,738,818

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

glutathione peroxidase 1

exacerbates
susceptibility

protein:decreased expression:mucosa of stomach (human)
mRNA:decreased expression:stomach, erythrocyte, lymphocyte (human)

PMID:24228025 PMID:27957666

RGD:152995446 RGD:152998894

NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987

G

glutathione peroxidase 4

susceptibility

mRNA:decreased expression:stomach, erythrocyte, lymphocyte (human)

NCBI chrNW_004936588:506,101...508,469
Ensembl chrNW_004936588:506,147...508,101

G

heterogeneous nuclear ribonucleoprotein A0

severity

mRNA:decreased expression:gastric adenocarcinoma (human)

NCBI chrNW_004936597:4,712,201...4,714,949

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of stomach
ClinVar Annotator: match by term: Adenocarcinoma of stomach | ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

interleukin 1 beta

protein:increased expression:blood serum (human)

NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165

G

interleukin 6

protein:increased expression:blood serum (human)

NCBI chrNW_004936549:7,015,595...7,016,246

G

interferon regulatory factor 1

NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636

G

lysine methyltransferase 2D

NCBI chrNW_004936512:6,819,240...6,860,852
Ensembl chrNW_004936512:6,822,057...6,854,451

G

signal transducer and activator of transcription 5B

exacerbates

mRNA:increased expression:stomach (human)

NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Adenocarcinoma of stomach | ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More...

NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083

G

mitogen-activated protein kinase kinase 4

severity

protein:increased expression:stomach (human)
protein:decreased expression: stomach (human)

PMID:10854223 PMID:17116802

RGD:150429764 RGD:150429780

NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662

G

mitogen-activated protein kinase 14

disease_progression
exacerbates

mRNA:increased expression:stomach (human)

PMID:30238991 PMID:32243890

RGD:151665345 RGD:151665792

NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232

G

NLR family apoptosis inhibitory protein

disease_progression

mRNA:increased expression:stomach (human)

NCBI chrNW_004936549:5,000,526...5,069,110

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of stomach

PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 More...

NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Adenocarcinoma of stomach
ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15647370 PMID:15805248 More...

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phospholipase C epsilon 1

ameliorates

human cells in a mouse model

NCBI chrNW_004936601:817,151...1,105,824
Ensembl chrNW_004936601:816,190...1,105,830

G

prostate transmembrane protein, androgen induced 1

mRNA:increased expression:stomach

NCBI chrNW_004936530:429,059...439,847
Ensembl chrNW_004936530:429,045...439,866

G

protein phosphatase 2 scaffold subunit Aalpha

ClinVar Annotator: match by term: Adenocarcinoma of stomach | ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265

NCBI chrNW_004936901:622,893...653,044
Ensembl chrNW_004936901:622,888...653,044

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Adenocarcinoma of stomach | ClinVar Annotator: match by term: Gastric adenocarcinoma

PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More...

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

protein tyrosine phosphatase non-receptor type 13

disease_progression

protein:increased expression:stomach

PMID:10660140 PMID:32536826

RGD:152599189 RGD:152975628

NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001

G

protein tyrosine phosphatase receptor type A

associated with metastasis; protein:increased expression:gastric mucosa (human)

NCBI chrNW_004936485:15,745,054...15,872,377
Ensembl chrNW_004936485:15,744,205...15,872,995

G

protein tyrosine phosphatase receptor type Z1

associated with metastasis; protein:increased expression:gastric mucosa (human)

NCBI chrNW_004936605:3,195,893...3,368,102
Ensembl chrNW_004936605:3,196,548...3,368,175

G

Rac family small GTPase 1

exacerbates

protein:increased expression:stomach (human)

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

ribonuclease T2

disease_progression

mRNA, protein:decreased expression:stomach (human)

NCBI chrNW_004936489:16,540,558...16,555,669
Ensembl chrNW_004936489:16,540,562...16,555,670

G

ring finger protein 43

severity

human cells in a mouse model

NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828

G

regulator of telomere elongation helicase 1

susceptibility

DNA:amplification:cds: (human)

NCBI chrNW_004936514:10,920,979...10,954,483
Ensembl chrNW_004936514:10,922,322...10,954,402

G

solute carrier family 7 member 5

protein:increased expression:mucosa:

NCBI chrNW_004936641:1,513,110...1,538,955

G

signal transducer and activator of transcription 1

exacerbates

mRNA:increased expression:stomach (human)

NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756

G

signal transducer and activator of transcription 2

mRNA:increased expression:stomach (human)

NCBI chrNW_004936646:747,178...763,449
Ensembl chrNW_004936646:748,727...761,287

G

signal transducer and activator of transcription 3

mRNA:increased expression:stomach (human)

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

G

signal transducer and activator of transcription 4

mRNA:increased expression:stomach (human)

NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689

G

signal transducer and activator of transcription 6

exacerbates

mRNA:increased expression:stomach (human)

NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157

G

tumor protein p53

ClinVar Annotator: match by term: Gastric adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of stomach
DNA:missense mutations, loss of heterozygosity:multiple

PMID:1359493 PMID:1565143 PMID:1565144 PMID:1631137 PMID:1978757 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

ubiquitin protein ligase E3 component n-recognin 5

ameliorates

human cell line in a mouse model

NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134

G

X-linked inhibitor of apoptosis

disease_progression

mRNA:increased expression:stomach (human)

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

G

exportin 1

exacerbates
ameliorates

protein:decreased expression:stomach (human)
human cell line in a mouse model

PMID:28373767 PMID:30115935

RGD:151665802 RGD:151667432

NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343

Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Gastric adenocarcinoma and proximal polyposis of the stomach

PMID:1316610 PMID:1324223 PMID:1944466 PMID:2996804 PMID:8381579 More...

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

gastric cardia adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

X-ray repair cross complementing 1

susceptibility

DNA:SNP:cds: p.R399Q (human)

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

gastric papillary adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

GLI family zinc finger 1

protein:increased expression:stomach

NCBI chrNW_004936646:1,622,308...1,629,787
Ensembl chrNW_004936646:1,622,308...1,629,779

G

smoothened, frizzled class receptor

protein:increased expression:stomach

NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281

gastric tubular adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

GLI family zinc finger 1

protein:increased expression:stomach

NCBI chrNW_004936646:1,622,308...1,629,787
Ensembl chrNW_004936646:1,622,308...1,629,779

G

smoothened, frizzled class receptor

protein:increased expression:stomach

NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281

gastrinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

insulin like growth factor 1 receptor

mRNA and protein: increased expression::poor prognosis for high expression

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

menin 1

DNA:mutations: :
CTD Direct Evidence: marker/mechanism

PMID:15944766 PMID:17961653

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

MET proto-oncogene, receptor tyrosine kinase

severity

associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human)

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

O-6-methylguanine-DNA methyltransferase

DNA:hypomethylation:promoter (human)

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

solute carrier family 2 member 2

mRNA:decreased expression:pancreatic islet

PMID:8421107 PMID:12114701

RGD:2324976 RGD:2324977

NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947

gastroesophageal adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

mitogen-activated protein kinase kinase kinase 13

NCBI chrNW_004936578:4,363,361...4,461,133
Ensembl chrNW_004936578:4,368,900...4,532,966

Glucagonoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

betacellulin

protein:increased expression:pancreas

NCBI chrNW_004936598:971,253...1,019,043
Ensembl chrNW_004936598:971,241...1,019,121

G

menin 1

DNA:deletion:exon
CTD Direct Evidence: marker/mechanism

PMID:17961653 PMID:20138042

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

solute carrier family 2 member 2

mRNA:decreased expression:pancreatic islet

PMID:8421107 PMID:12114701

RGD:2324976 RGD:2324977

NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947

G

somatostatin receptor 4

NCBI chrNW_004936620:2,575,880...2,577,761
Ensembl chrNW_004936620:2,576,598...2,577,761

hepatocellular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936516:2,030,032...2,052,025
Ensembl chrNW_004936516:2,029,715...2,052,041

G

ATP binding cassette subfamily A member 1

severity

mRNA:decreased expression:liver (human)

PMID:16941710 PMID:30580964

RGD:1598532 RGD:24922199

NCBI chrNW_004936559:7,177,887...7,312,660
Ensembl chrNW_004936559:7,177,904...7,312,741

G

ATP binding cassette subfamily B member 1

susceptibility

CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :c.3751G>A(human)
DNA:polymorphism: : c.1465C > T(human)

PMID:17510421 PMID:23488625 PMID:24175826 PMID:25625052

RGD:11041138 RGD:14700904 RGD:14700905

NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427

G

ATP binding cassette subfamily B member 4

CTD Direct Evidence: marker/mechanism
OMIM:114550

NCBI chrNW_004936763:1,339,849...1,415,528
Ensembl chrNW_004936763:1,339,824...1,415,586

G

ATP binding cassette subfamily C member 3

mRNA:increased expression:liver

NCBI chrNW_004936490:11,039,968...11,086,670
Ensembl chrNW_004936490:11,040,445...11,086,566

G

ATP binding cassette subfamily E member 1

mRNA:increased expression:liver (human)

NCBI chrNW_004936535:3,956,490...3,985,002
Ensembl chrNW_004936535:3,955,682...3,985,223

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669

G

acetyl-CoA carboxylase alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:927,769...1,191,483
Ensembl chrNW_004936490:927,769...1,191,481

G

alkaline ceramidase 3

disease_progression

NCBI chrNW_004936498:5,496,991...5,653,206
Ensembl chrNW_004936498:5,496,991...5,653,206

G

ATP citrate lyase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:16,758,001...16,798,152
Ensembl chrNW_004936490:16,757,985...16,798,237

G

aconitase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:407,482...452,538
Ensembl chrNW_004936492:407,482...452,537

G

acyl-CoA oxidase 1

CTD Direct Evidence: marker/mechanism

PMID:12771043 PMID:15565109

NCBI chrNW_004936594:1,115,607...1,140,085
Ensembl chrNW_004936594:1,112,565...1,140,228

G

acyl-CoA synthetase long chain family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144

G

actin beta

CTD Direct Evidence: marker/mechanism

PMID:19363144 PMID:21472284

NCBI chrNW_004936765:667,107...670,627
Ensembl chrNW_004936765:667,053...670,672

G

ADAM metallopeptidase with thrombospondin type 1 motif 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936640:959,405...967,305
Ensembl chrNW_004936640:959,417...968,842

G

ADAM metallopeptidase with thrombospondin type 1 motif 13

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936669:3,449,259...3,478,471
Ensembl chrNW_004936669:3,456,494...3,478,512

G

adducin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:20,695,109...20,766,053
Ensembl chrNW_004936477:20,691,951...20,766,152

G

adhesion G protein-coupled receptor G7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936630:2,569,513...2,624,252
Ensembl chrNW_004936630:2,569,513...2,624,252

G

adiponectin, C1Q and collagen domain containing

susceptibility

DNA:SNP:intron:+276T>G (rs1501299) (human)

NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928

G

adrenoceptor alpha 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710

G

adrenoceptor alpha 2B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936744:249,673...253,040
Ensembl chrNW_004936744:251,467...252,816

G

alpha fetoprotein

disease_progression
treatment
severity

associated with hepatitis B
protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism

PMID:9029167 PMID:15276417 PMID:22147961 PMID:22392353 PMID:24012840 More...

RGD:125097525 RGD:126790579 RGD:126790583 RGD:14401581 RGD:152177911

NCBI chrNW_004936598:2,058,474...2,077,711
Ensembl chrNW_004936598:2,058,117...2,077,728

G

activation induced cytidine deaminase

NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601

G

adenylate kinase 3

protein:decreased expression:liver

NCBI chrNW_004936503:497,391...517,011
Ensembl chrNW_004936503:496,965...516,888

G

aldo-keto reductase family 1 member A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214

G

aldo-keto reductase family 1 member B

protein:increased expression:liver (rat)
protein:increased expression:liver (human)

PMID:19422879 PMID:21683810

RGD:5509919 RGD:8548685

NCBI chrNW_004936579:1,312,175...1,328,397

G

AKT serine/threonine kinase 1

treatment
exacerbates

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver

PMID:25999787 PMID:31801250 PMID:32045588 PMID:37460115

RGD:151893509 RGD:152177911 RGD:408364960

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

AKT serine/threonine kinase 2

protein:increased phosphorylation:liver (mouse)
protein:increased phosphorylation:liver cancer cell (rat)

PMID:19309364 PMID:28100771

RGD:127285675 RGD:2313299

NCBI chrNW_004936661:2,652,568...2,694,039
Ensembl chrNW_004936661:2,652,566...2,694,086

G

aldehyde dehydrogenase 2 family member

susceptibility
no_association
severity

associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human)
DNA:missense mutation:cds: (rs671) (human)
protein:decreased expression: liver (human)
DNA:missense mutation:exon 12: (human)
associated with hepatitis C:DNA:SNP:exon 12 (human)
DNA:missense mutation:cds, exon 12:p.E487K (human)
mRNA, protein:decreased expression:liver (human)
associated with alcohol use disorder;DNA:missense mutation:cds: (human)
associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human)

PMID:1916152 PMID:10737710 PMID:12940444 PMID:18439068 PMID:25778454 More...

RGD:11054822 RGD:14696699 RGD:14696778 RGD:14696779 RGD:14700899 RGD:15036809 RGD:15042857 RGD:15042859 RGD:15042862

NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414

G

aldehyde dehydrogenase 7 family member A1

severity

mRNA:altered expression:liver tumor (human)

NCBI chrNW_004936575:6,467,224...6,506,052
Ensembl chrNW_004936575:6,467,340...6,506,006

G

aldolase, fructose-bisphosphate C

mRNA:increased expression:liver

NCBI chrNW_004936538:4,798,991...4,802,700
Ensembl chrNW_004936538:4,798,989...4,802,994

G

ALX homeobox 4

ameliorates

mRNA, protein:decreased expression:liver

PMID:28081728 PMID:31132711

RGD:153323329 RGD:153323330

NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000

G

angiopoietin like 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:491,330...499,409
Ensembl chrNW_004936659:487,983...499,448

G

ankyrin 3

protein:decreased expression:liver

NCBI chrNW_004936614:2,664,594...2,976,174

G

anillin actin binding protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:11,873,676...11,934,425
Ensembl chrNW_004936478:11,880,103...11,933,247

G

ANTXR cell adhesion molecule 1

treatment

NCBI chrNW_004936491:13,288,986...13,516,878
Ensembl chrNW_004936491:13,288,717...13,516,984

G

annexin A10

disease_progression

mRNA:decreased expression:liver (human)

NCBI chrNW_004936516:584,631...644,023
Ensembl chrNW_004936516:564,432...643,586

G

annexin A2

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503

G

annexin A4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:13,982,926...14,047,690
Ensembl chrNW_004936491:13,982,677...14,047,690

G

annexin A6

disease_progression

associated with tumor vascularization; protein:decreased expression:liver tumor (human)

NCBI chrNW_004936647:3,978,047...4,029,485
Ensembl chrNW_004936647:3,976,903...4,029,485

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:1316610 PMID:8381579 PMID:8381580 PMID:8395941 PMID:9101302 More...

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

amyloid P component, serum

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936740:979,007...987,312
Ensembl chrNW_004936740:986,460...987,361

G

apurinic/apyrimidinic endodeoxyribonuclease 1

treatment

CTD Direct Evidence: marker/mechanism

PMID:25109342 PMID:33841550

NCBI chrNW_004936877:666,545...669,351
Ensembl chrNW_004936877:666,523...669,338

G

apelin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936479:1,889,930...1,899,811
Ensembl chrNW_004936479:1,890,229...1,899,730

G

apolipoprotein A1

disease_progression

protein:decreased expression:plasma (human)
associated with hepatitis B;
CTD Direct Evidence: marker/mechanism

PMID:21472284 PMID:23935864 PMID:31211449

RGD:153350082 RGD:25671438

NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854

G

apolipoprotein A2

associated with hepatitis B; mRNA:increased expression:liver

NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910

G

apolipoprotein A4

disease_progression

associated with hepatitis B;

NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127

G

apolipoprotein C1

disease_progression

associated with hepatitis B;

NCBI chrNW_004936706:1,519,248...1,520,102

G

apolipoprotein C2

associated with hepatitis B; mRNA:increased expression:liver

NCBI chrNW_004936706:1,531,219...1,531,921

G

apolipoprotein C3

susceptibility
disease_progression

associated with Chronic Hepatitis B;DNA:SNP: :rs2854116(human)
associated with hepatitis B;

PMID:27547913 PMID:31211449

RGD:153344620 RGD:153350082

NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603

G

apolipoprotein C4

disease_progression

associated with hepatitis B;

NCBI chrNW_004936706:1,528,187...1,530,028

G

apolipoprotein E

protein:increased expression:liver, serum (mouse)

NCBI chrNW_004936706:1,512,438...1,516,805

G

adenine phosphoribosyltransferase

protein:increased activity:hepatoma (rat)

NCBI chrNW_004936641:913,674...916,312
Ensembl chrNW_004936641:913,475...918,748

G

androgen receptor

CTD Direct Evidence: therapeutic

NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932

G

Rho GTPase activating protein 11A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936673:1,290,476...1,308,753

G

Rho GTPase activating protein 44

exacerbates

protein:decreased expression:liver (human)

NCBI chrNW_004936595:5,373,645...5,542,915
Ensembl chrNW_004936595:5,373,476...5,543,073

G

Rho guanine nucleotide exchange factor 39

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:3,660,364...3,663,664
Ensembl chrNW_004936524:3,660,454...3,663,696

G

AT-rich interaction domain 1A

exacerbates
treatment

associated with non-alcoholic steatohepatitis
mRNA, protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:liver (human)
human gene in mouse model

PMID:22561517 PMID:22634756 PMID:22922871 PMID:25975202 PMID:26569409 More...

RGD:11344640 RGD:125097485 RGD:125097495 RGD:125097519 RGD:126790634

NCBI chrNW_004936474:11,148,857...11,197,312

G

AT-rich interaction domain 1B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:8,811,094...9,202,423
Ensembl chrNW_004936489:9,087,697...9,205,203

G

AT-rich interaction domain 2

disease_progression
exacerbates

associated with hepatitis B;protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:21822264 PMID:22634756 PMID:25701229 PMID:27351279 PMID:28498550 More...

RGD:150340708 RGD:150340711 RGD:150340712 RGD:150429631

NCBI chrNW_004936512:4,020,303...4,199,390
Ensembl chrNW_004936512:4,020,966...4,196,459

G

AT-rich interaction domain 3A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:389,213...418,360
Ensembl chrNW_004936588:394,469...415,893

G

arrestin beta 2

treatment

NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520

G

anti-silencing function 1B histone chaperone

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:2,772,310...2,782,687
Ensembl chrNW_004936659:2,770,900...2,782,748

G

argininosuccinate lyase

disease_progression

associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human)

NCBI chrNW_004936543:7,688,788...7,699,842
Ensembl chrNW_004936543:7,688,741...7,699,851

G

asparagine synthetase (glutamine-hydrolyzing)

protein:increased activity:serum (rat)

NCBI chrNW_004936585:2,834,202...2,854,740
Ensembl chrNW_004936585:2,834,008...2,855,387

G

asparaginase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:1,140,651...1,163,608
Ensembl chrNW_004936621:1,140,658...1,163,589

G

assembly factor for spindle microtubules

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:18676753 PMID:28284560

NCBI chrNW_004936567:6,653,382...6,701,856
Ensembl chrNW_004936567:6,653,728...6,701,752

G

argininosuccinate synthase 1

disease_progression

associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human)

PMID:12359751 PMID:30901224

RGD:152995286 RGD:4140479

NCBI chrNW_004936487:17,482,307...17,527,407
Ensembl chrNW_004936487:17,486,826...17,527,435

G

autophagy related 101

disease_progression

NCBI chrNW_004936512:9,518,128...9,525,986
Ensembl chrNW_004936512:9,518,074...9,526,961

G

autophagy related 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:1,938,720...2,179,239
Ensembl chrNW_004936602:1,935,507...2,179,256

G

ATM serine/threonine kinase

exacerbates

protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism

PMID:12866955 PMID:19919837

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

ATP synthase peripheral stalk-membrane subunit b

associated with hepatitis C

NCBI chrNW_004936690:120,572...135,509

G

ATP synthase peripheral stalk subunit d

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:354,416...359,415
Ensembl chrNW_004936594:353,980...359,414

G

aurora kinase A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936875:295,238...310,457

G

aurora kinase B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:1,435,601...1,437,423
Ensembl chrNW_004936595:1,435,852...1,440,351

G

axin 1

disease_progression

associated with Hepatitis B, Chronic,DNA:SNP, haplotype:exon:(rs1805105) T>C (human)
ClinVar Annotator: match by term: AXIN1-related condition | ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
protein:decreased expression:liver (human)

RGD
ClinVar
OMIM

PMID:10700176 PMID:25741868 PMID:26968103 PMID:28492532 PMID:31514071 More...

RGD:14402039 RGD:150530482

NCBI chrNW_004936501:599,963...633,837
Ensembl chrNW_004936501:599,919...633,873

G

axin 2

protein:increased expression:liver:

NCBI chrNW_004936541:7,155,963...7,242,466
Ensembl chrNW_004936541:7,211,985...7,242,470

G

alpha-2-glycoprotein 1, zinc-binding

disease_progression

mRNA:decreased expression:liver
associated with hepatitis B;mRNA:decreased expression:liver

PMID:22625427 PMID:26902423 PMID:27993894

RGD:153350130 RGD:153350132 RGD:153350133

NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190

G

antizyme inhibitor 1

disease_progression

RNA:increased editing:liver

NCBI chrNW_004936470:40,801,943...40,832,543
Ensembl chrNW_004936470:40,801,943...40,834,003

G

barrier to autointegration nuclear assembly factor 1

treatment

mRNA, protein:increased expression:liver (human)
mRNA, protein:increased expression:liver (rat)

NCBI chrNW_004936599:3,553,190...3,555,167
Ensembl chrNW_004936599:3,553,193...3,555,162

G

BCL2 associated X, apoptosis regulator

treatment

NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820

G

BCL2 apoptosis regulator

treatment

mRNA:increased expression:liver (mouse)

PMID:28100771 PMID:33841550

RGD:127285675 RGD:152998960

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

BCL2 like 1

treatment

mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism|therapeutic

PMID:10629087 PMID:11509945 PMID:28100771 PMID:33841550

RGD:127285675 RGD:152998960

NCBI chrNW_004936485:18,654,046...18,707,324

G

beta-carotene oxygenase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936612:2,262,115...2,294,287
Ensembl chrNW_004936612:2,262,066...2,294,255

G

BCL6 corepressor like 1

disease_progression

PMID:26879601 PMID:29679906

RGD:11556159 RGD:150340705

NCBI chrNW_004936479:1,539,676...1,605,647
Ensembl chrNW_004936479:1,538,051...1,606,344

G

BH3 interacting domain death agonist

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936807:708,340...750,127
Ensembl chrNW_004936807:708,276...750,093

G

baculoviral IAP repeat containing 3

treatment
exacerbates
ameliorates

human cell line in a mouse model
associated with hepatitis B;mRNA, protein:increased expression:liver (human)

PMID:22682366 PMID:22820591 PMID:30210622 PMID:30368883 PMID:33310033

RGD:152998937 RGD:152998984 RGD:152998986 RGD:152998988 RGD:152999010

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

disease_progression

CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human)

PMID:16086872 PMID:20514400 PMID:31964418

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

baculoviral IAP repeat containing 7

exacerbates

mRNA:increased expression:liver (human)

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

basic leucine zipper nuclear factor 1

disease_progression

NCBI chrNW_004936481:17,261,399...17,280,642
Ensembl chrNW_004936481:17,260,472...17,281,309

G

BMI1 proto-oncogene, polycomb ring finger

treatment

NCBI chrNW_004936520:5,707,542...5,716,966
Ensembl chrNW_004936520:5,707,778...5,717,024

G

BMP binding endothelial regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:9,705,634...9,941,382
Ensembl chrNW_004936478:9,705,604...9,941,340

G

B-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

basigin (Ok blood group)

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287

G

BTG anti-proliferation factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936567:1,310,525...1,314,469
Ensembl chrNW_004936567:1,309,658...1,314,515

G

BUB1 mitotic checkpoint serine/threonine kinase B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:3,631,760...3,696,024
Ensembl chrNW_004936471:3,633,536...3,695,684

G

complement C3

NCBI chrNW_004936588:3,985,732...4,023,221

G

complement C9

CTD Direct Evidence: marker/mechanism

PMID:19363144 PMID:28284560

NCBI chrNW_004936518:2,947,956...2,994,892
Ensembl chrNW_004936518:2,958,995...2,994,880

G

carbonic anhydrase 12

disease_progression
ameliorates

mRNA:altered expression:liver

PMID:29900055 PMID:31934040 PMID:35362480

RGD:153352325 RGD:153352328 RGD:155226869

NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987

G

carbonic anhydrase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936544:362,591...379,151
Ensembl chrNW_004936544:362,591...380,223

G

carbonic anhydrase 9

mRNA:altered expression:liver

NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433

G

calcium binding protein 39

disease_progression

NCBI chrNW_004936525:5,955,252...6,002,917
Ensembl chrNW_004936525:5,954,978...6,032,644

G

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

DNA:amplification:cds (rat)
mRNA:increased expression:liver

PMID:2888462 PMID:2914957 PMID:7053379

RGD:10755426 RGD:2303530 RGD:5132587

NCBI chrNW_004936493:5,308,268...5,332,934
Ensembl chrNW_004936493:5,310,228...5,332,918

G

cell adhesion molecule 1

DNA, mRNA, protein:hypermethylation, decreased expression:promoter:liver

NCBI chrNW_004936542:569,739...883,738
Ensembl chrNW_004936542:565,843...883,609

G

cell adhesion molecule 2

disease_progression

mRNA, protein:decreased expression:liver

NCBI chrNW_004936610:3,304,556...4,297,745
Ensembl chrNW_004936610:3,305,551...3,598,837

G

calreticulin

exacerbates
treatment

protein:increased expression:liver (human)
human cells and recombinant gene in a mouse model

PMID:12096119 PMID:24997628 PMID:27055635

RGD:150521681 RGD:150521690 RGD:150521691

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

calcium/calmodulin dependent protein kinase II inhibitor 1

NCBI chrNW_004936474:6,463,691...6,466,641
Ensembl chrNW_004936474:6,461,050...6,466,641

G

cyclase associated actin cytoskeleton regulatory protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936552:3,395,785...3,501,949
Ensembl chrNW_004936552:3,395,649...3,501,940

G

calpain 3

mRNA:decreased expression:skeletal muscle

NCBI chrNW_004936471:5,667,839...5,711,822
Ensembl chrNW_004936471:5,668,169...5,711,075

G

coactivator associated arginine methyltransferase 1

mRNA,protein:increased expression:liver:

NCBI chrNW_004936659:1,071,883...1,120,917
Ensembl chrNW_004936659:1,090,164...1,123,920

G

caspase 3

treatment

PMID:29133031 PMID:33841550

RGD:13782296 RGD:152998960

NCBI chrNW_004936554:4,571,072...4,593,765

G

caspase 8

treatment
severity

associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human)

PMID:28643196 PMID:29133031

RGD:13782296 RGD:14695027

NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922

G

caspase 9

treatment

NCBI chrNW_004936474:3,178,097...3,196,130

G

catalase

disease_progression

CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human)

PMID:21907168 PMID:33010264

NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422

G

core-binding factor subunit beta

mRNA:decreased expression:liver

NCBI chrNW_004936475:17,537,273...17,589,383
Ensembl chrNW_004936475:17,537,236...17,589,330

G

Cbl proto-oncogene

disease_progression

NCBI chrNW_004936542:4,136,389...4,235,746
Ensembl chrNW_004936542:4,136,511...4,228,288

G

carbonyl reductase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:6,569,708...6,591,266
Ensembl chrNW_004936500:6,458,721...6,591,928

G

chromobox 2

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936594:3,886,926...3,902,459
Ensembl chrNW_004936594:3,893,772...3,900,000

G

chromobox 4

disease_progression

protein:increased expression:cytoplasm:

PMID:23943028 PMID:24838576

RGD:9586738 RGD:9586739

NCBI chrNW_004936594:3,943,933...3,950,124
Ensembl chrNW_004936594:3,943,924...3,950,196

G

chromobox 7

mRNA:decreased expression:liver

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

collagen and calcium binding EGF domains 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:5,290,068...5,321,656
Ensembl chrNW_004936497:5,290,077...5,321,876

G

C-C motif chemokine ligand 1

mRNA:increased expression:liver (mouse)

NCBI chrNW_004936538:781,687...784,199
Ensembl chrNW_004936538:781,687...784,199

G

C-C motif chemokine ligand 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:290,452...293,330
Ensembl chrNW_004936490:290,437...293,360

G

C-C motif chemokine ligand 5

treatment
susceptibility

associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human)
DNA:polymorphisms:promoter:-403G>A,-28C>G (human)

PMID:21610221 PMID:22374185 PMID:28011329

RGD:14995306 RGD:14995333 RGD:14995338

NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965

G

cellular communication network factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936608:152,174...155,123
Ensembl chrNW_004936608:151,838...155,358

G

cyclin A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:30,574,957...30,586,596
Ensembl chrNW_004936472:30,573,812...30,586,559

G

cyclin B1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704

G

cyclin B2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:20,216,435...20,238,543

G

cyclin D1

susceptibility

mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism
associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human)

PMID:12029619 PMID:19919837 PMID:22649188 PMID:25822088 PMID:25851350 More...

RGD:127285675 RGD:14401586

Ensembl chrNW_004936599:973,838...983,316

G

cyclin D2

severity
disease_progression
susceptibility

associated with hepatitis B
DNA:hypermethylation:CpG site
associated with Chronic Hepatitis C;DNA:SNP: :rs1049606(human)

PMID:22004425 PMID:31059558 PMID:33320844

RGD:151664743 RGD:151665109 RGD:151665169

NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810

G

cyclin E1

ameliorates

CTD Direct Evidence: marker/mechanism

PMID:12029619 PMID:17196522 PMID:22634754 PMID:28100771 PMID:29551768

RGD:127285675 RGD:153297807 RGD:2289277

NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008

G

cyclin F

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:1,596,897...1,620,588
Ensembl chrNW_004936694:1,596,766...1,620,643

G

cyclin G1

treatment
severity
disease_progression

protein:decreased expression:liver (human)
protein:increased expression:liver (human)
human cells in mouse model

PMID:19584283 PMID:22835824 PMID:23804702 PMID:24034575 PMID:25431954 More...

RGD:151356922 RGD:151356932 RGD:151356933 RGD:151356967 RGD:151356970 RGD:151356981 RGD:151361198 RGD:151361200

NCBI chrNW_004936515:614,287...621,213
Ensembl chrNW_004936515:614,290...619,963

G

cyclin G2

NCBI chrNW_004936676:1,026,113...1,035,313
Ensembl chrNW_004936676:1,025,856...1,037,698

G

CD274 molecule

disease_progression

associated with hepatitis B
CTD Direct Evidence: marker/mechanism
associated with hepatitis B

PMID:21912640 PMID:22396772 PMID:30267213

RGD:40818240 RGD:41410800

NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602

G

CD276 molecule

CTD Direct Evidence: therapeutic

NCBI chrNW_004936471:32,864,778...32,892,044
Ensembl chrNW_004936471:32,864,781...32,892,095

G

CD34 molecule

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936557:5,030,788...5,051,864
Ensembl chrNW_004936557:5,030,441...5,051,868

G

CD40 ligand

NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403

G

CD68 molecule

severity

protein:increased expression:liver (human)

NCBI chrNW_004936595:858,289...861,131

G

cell division cycle 20

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:24,760,258...24,765,069
Ensembl chrNW_004936474:24,760,298...24,767,725

G

cell division cycle 25C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:7,471,722...7,499,781
Ensembl chrNW_004936531:7,471,722...7,499,766

G

cell division cycle 27

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma

NCBI chrNW_004936541:2,700,997...2,762,180
Ensembl chrNW_004936541:2,700,997...2,762,147

G

cell division cycle 45

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936619:3,420,110...3,452,419
Ensembl chrNW_004936619:3,420,191...3,452,436

G

cell division cycle 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:15,360,477...15,370,519
Ensembl chrNW_004936490:15,360,504...15,370,008

G

cell division cycle associated 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936757:1,195,604...1,249,367
Ensembl chrNW_004936757:1,195,567...1,248,237

G

cell division cycle associated 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936709:966,559...969,667
Ensembl chrNW_004936709:967,294...968,896

G

cell division cycle associated 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:4,285,007...4,291,875
Ensembl chrNW_004936599:4,284,958...4,291,874

G

cell division cycle associated 8

disease_progression

mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism

PMID:28284560 PMID:35693827

NCBI chrNW_004936474:19,895,681...19,912,451
Ensembl chrNW_004936474:19,895,640...19,912,933

G

cadherin 1

severity

protein:decreased expression:liver
DNA:hypermethylation
mRNA:increased expression:liver

PMID:17295234 PMID:18837082 PMID:24840851 PMID:30697077

RGD:14402045 RGD:14402046 RGD:14402047 RGD:2289638

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

cadherin 13

CTD Direct Evidence: marker/mechanism

PMID:18425332 PMID:18553387 PMID:28284560

NCBI chrNW_004936641:3,925,185...4,223,421
Ensembl chrNW_004936641:3,931,033...4,224,101

G

cyclin dependent kinase 1

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)

PMID:19136513 PMID:28284560

NCBI chrNW_004936614:2,300,682...2,313,611
Ensembl chrNW_004936614:2,300,513...2,313,624

G

cyclin dependent kinase 12

exacerbates

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936490:14,674,783...14,759,433
Ensembl chrNW_004936490:14,674,800...14,738,818

G

cyclin dependent kinase 13

onset

DNA:amplification: :

NCBI chrNW_004936478:15,296,055...15,387,749
Ensembl chrNW_004936478:15,296,055...15,388,309

G

cyclin dependent kinase 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:3,030,964...3,504,294
Ensembl chrNW_004936621:2,946,035...3,504,306

G

cyclin dependent kinase 4

treatment

CTD Direct Evidence: marker/mechanism

PMID:26189965 PMID:33841550

NCBI chrNW_004936646:1,886,262...1,889,260

G

cyclin dependent kinase inhibitor 1A

OMIM:114550

NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182

G

cyclin dependent kinase inhibitor 1B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936587:4,573,166...4,578,480
Ensembl chrNW_004936587:4,572,728...4,578,461

G

cyclin dependent kinase inhibitor 1C

severity

protein:decreased expression:liver (human)

NCBI chrNW_004936794:1,023,891...1,025,470

G

cyclin dependent kinase inhibitor 2B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936652:3,576,975...3,582,790
Ensembl chrNW_004936652:3,538,986...3,581,159

G

cyclin dependent kinase inhibitor 2C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936522:9,769,761...9,775,374
Ensembl chrNW_004936522:9,769,756...9,775,077

G

cyclin dependent kinase inhibitor 3

severity
treatment

mRNA:increased expression:liver
protein:decreased expression:liver
associated with alcoholism; protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:22390936 PMID:23292002 PMID:27314282 PMID:28284560

RGD:15090800 RGD:15090801 RGD:15090802

NCBI chrNW_004936697:669,154...684,077
Ensembl chrNW_004936697:670,785...683,996

G

chromatin licensing and DNA replication factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936641:916,695...925,411
Ensembl chrNW_004936641:917,435...920,981

G

CCAAT enhancer binding protein alpha

CTD Direct Evidence: marker/mechanism

PMID:16288022 PMID:21785164

NCBI chrNW_004936570:2,513,561...2,516,213

G

CCAAT enhancer binding protein delta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936590:4,919,862...4,920,612

G

cadherin EGF LAG seven-pass G-type receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:437,476...464,012
Ensembl chrNW_004936529:437,418...464,017

G

centromere protein A

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)

PMID:21956590 PMID:28284560

NCBI chrNW_004936493:5,715,274...5,720,816
Ensembl chrNW_004936493:5,714,782...5,720,837

G

centromere protein E

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936520:188,601...265,904
Ensembl chrNW_004936520:188,628...265,733

G

centromere protein F

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936628:3,642,281...3,695,262
Ensembl chrNW_004936628:3,643,000...3,695,221

G

centromere protein M

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:75,196...88,446
Ensembl chrNW_004936492:75,238...87,912

G

centromere protein U

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936554:4,497,675...4,536,274
Ensembl chrNW_004936554:4,500,486...4,536,239

G

centromere protein W

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936639:3,173,832...3,184,439
Ensembl chrNW_004936639:3,173,385...3,184,454

G

centrosomal protein 131

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:4,914,174...4,938,364
Ensembl chrNW_004936594:4,914,358...4,938,394

G

centrosomal protein 164

susceptibility

associated with Chronic Hepatitis C;DNA:SNP: :rs573455 (human)

NCBI chrNW_004936542:2,544,677...2,609,753
Ensembl chrNW_004936542:2,544,665...2,609,792

G

centrosomal protein 55

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:1,455,641...1,474,045
Ensembl chrNW_004936601:1,455,641...1,474,045

G

cholesteryl ester transfer protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073

G

complement factor properdin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936502:13,391,613...13,398,723
Ensembl chrNW_004936502:13,391,535...13,397,440

G

chromatin assembly factor 1 subunit B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:6,262,207...6,288,833
Ensembl chrNW_004936500:6,262,229...6,288,839

G

chromodomain helicase DNA binding protein 4

exacerbates

protein:increased expression:liver (human)
mRNA:increased expression:liver (human)

PMID:26095183 PMID:28486105 PMID:32070428

RGD:11571740 RGD:153323299 RGD:153323308

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

chromodomain helicase DNA binding protein 5

mRNA:decreased expression:liver

NCBI chrNW_004936623:988,423...1,046,969
Ensembl chrNW_004936623:991,193...1,046,969

G

cytoskeleton associated protein 2 like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936783:1,175,044...1,194,407
Ensembl chrNW_004936783:1,173,627...1,193,813

G

cytoskeleton associated protein 4

disease_progression

associated with tumor vascularization; mRNA,protein:increased expression:liver tumor (human)

NCBI chrNW_004936492:8,635,275...8,638,696

G

claudin 1

severity

protein:decreased expression:liver (human)
protein:increased expression:liver (human)
associated with liver cirrhosis;protein:increased expression:liver (human)

PMID:17270214 PMID:24696415 PMID:24815833

RGD:26884345 RGD:26884348 RGD:26884352

NCBI chrNW_004936578:98,489...113,125
Ensembl chrNW_004936578:98,273...113,153

G

C-type lectin domain family 1 member B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936902:504,095...510,261
Ensembl chrNW_004936902:504,095...510,261

G

C-type lectin domain family 4 member G

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:4,737,278...4,740,750
Ensembl chrNW_004936588:4,738,182...4,740,750

G

CLPTM1 like

susceptibility
disease_progression

DNA:SNPs::rs401681(human)
DNA:SNP: :rs401681(human)

PMID:25339005 PMID:29042796

RGD:150530496 RGD:150537100

NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750

G

collectrin, amino acid transport regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:5,040,831...5,124,611
Ensembl chrNW_004936470:5,040,795...5,124,192

G

carnosine dipeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936616:3,955,847...3,984,021

G

contactin associated protein family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:24,809,813...25,049,362
Ensembl chrNW_004936475:24,809,531...25,049,854

G

collagen type XV alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:7,481,541...7,591,452
Ensembl chrNW_004936524:7,481,761...7,590,544

G

collagen type XVIII alpha 1 chain

severity

Protein:increased expression

NCBI chrNW_004936778:847,473...943,038

G

collectin subfamily member 10

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:27,416,471...27,449,206
Ensembl chrNW_004936470:27,416,494...27,449,206

G

catechol-O-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936619:3,847,059...3,883,866
Ensembl chrNW_004936619:3,876,299...3,882,747

G

COP9 signalosome subunit 5

severity

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)

PMID:20698225 PMID:26606000

NCBI chrNW_004936496:7,035,973...7,050,538
Ensembl chrNW_004936496:7,035,924...7,050,786

G

ceruloplasmin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936519:6,431,156...6,473,183
Ensembl chrNW_004936519:6,431,144...6,481,858

G

cytoplasmic polyadenylation element binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:2,470,021...2,616,451
Ensembl chrNW_004936601:2,470,036...2,610,942

G

carbamoyl-phosphate synthase 1

disease_progression

associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human)

NCBI chrNW_004936586:5,739,038...5,850,317
Ensembl chrNW_004936586:5,739,337...5,850,312

G

CREB binding protein

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: LIVER CELL CARCINOMA

PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More...

NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617

G

corticotropin releasing hormone binding protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936549:64,866...78,272
Ensembl chrNW_004936549:64,866...78,272

G

C-reactive protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606

G

colony stimulating factor 1 receptor

exacerbates
severity

DNA:hypomethylation
mRNA:increased expression:liver (human)
protein:increased expression:liver (human)
protein:increased expression: liver (human)
DNA:hypomethylation:promoter (human)

PMID:11412385 PMID:14969845 PMID:20551429 PMID:32724427 PMID:32760707

RGD:150524279 RGD:150524282 RGD:150524286 RGD:150524301 RGD:150524302

NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923

G

colony stimulating factor 2

treatment

NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864

G

C-terminal Src kinase

protein:decreased expression:liver

NCBI chrNW_004936471:33,757,778...33,777,871
Ensembl chrNW_004936471:33,757,772...33,778,933

G

CUB and Sushi multiple domains 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936615:1,677,845...2,063,781
Ensembl chrNW_004936615:1,679,243...3,319,300

G

chondroitin sulfate proteoglycan 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:34,438,676...34,475,005
Ensembl chrNW_004936471:34,438,676...34,475,052

G

cysteine and serine rich nuclear protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:28,398,528...28,409,962
Ensembl chrNW_004936473:28,398,543...28,409,962

G

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNPs: :rs231775,rs231725(human)
protein:increased expression:CD4+ and CD8+ T cells:

PMID:23432218 PMID:28648905

RGD:14398741 RGD:14398742

NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643

G

catenin beta 1

susceptibility
severity
exacerbates

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: AXIN1-related condition | ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA
associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human)
associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human)
DNA:Mutations:exon:
DNA:missense mutations:exon 3:multiple (human)

OMIM
ClinVar
RGD

PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More...

RGD:14402039 RGD:14402040 RGD:14402052 RGD:150429592

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

cathepsin D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936816:680,798...690,959
Ensembl chrNW_004936816:680,798...691,039

G

cathepsin L

NCBI chrNW_004936680:3,047,355...3,050,640

G

chromosome unknown C14orf180 homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:781,145...790,441

G

cut like homeobox 1

mRNA:increased expression:liver (human)

NCBI chrNW_004936543:1,482,606...1,781,294
Ensembl chrNW_004936543:1,485,970...1,796,070

G

C-X-C motif chemokine ligand 10

treatment
disease_progression

PMID:27245433 PMID:28592115 PMID:28638480

RGD:27095889 RGD:27095898 RGD:27095899

NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106

G

C-X-C motif chemokine ligand 11

mRNA:increased expression:liver (mouse)

NCBI chrNW_004936676:72,383...73,697
Ensembl chrNW_004936676:71,667...73,738

G

C-X-C motif chemokine ligand 12

CTD Direct Evidence: marker/mechanism

PMID:19363144 PMID:28284560

NCBI chrNW_004936617:4,224,131...4,239,080
Ensembl chrNW_004936617:4,224,131...4,238,796

G

C-X-C motif chemokine ligand 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936597:2,746,415...2,754,169
Ensembl chrNW_004936597:2,746,296...2,754,716

G

C-X-C motif chemokine receptor 4

severity
treatment

protein:increased expression:liver (human)
human cells in mouse model

PMID:30034941 PMID:33574707

RGD:151665327 RGD:151665331

NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459

G

CYLD lysine 63 deubiquitinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118

G

DAB2 interacting protein

severity

mRNA:decreased expression:liver (human)
protein:decreased expression:liver (human)

PMID:22168621 PMID:31176165

RGD:151665110 RGD:151665148

NCBI chrNW_004936487:10,056,809...10,243,021
Ensembl chrNW_004936487:10,145,278...10,243,174

G

dopamine beta-hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936669:3,302,014...3,326,233
Ensembl chrNW_004936669:3,301,802...3,320,643

G

decorin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936507:7,887,259...7,923,055
Ensembl chrNW_004936507:7,884,654...7,922,961

G

discoidin domain receptor tyrosine kinase 1

severity

mRNA:increased expression:liver (human)

NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833

G

discoidin domain receptor tyrosine kinase 2

disease_progression
treatment

PMID:26362312 PMID:33969575

RGD:11086753 RGD:150429748

NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139

G

DEAD-box helicase 3 X-linked

sexual_dimorphism
exacerbates

associated with hepatitis B; mRNA,protein:decreased expression:liver (human)

PMID:16301996 PMID:30297359

RGD:151356499 RGD:151356660

NCBI chrNW_004936502:7,770,896...7,820,555
Ensembl chrNW_004936502:7,804,824...7,820,569

G

DEP domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936591:3,303,915...3,323,462
Ensembl chrNW_004936591:3,304,067...3,323,462

G

DEP domain containing 1B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936480:7,750,244...7,841,556
Ensembl chrNW_004936480:7,750,241...7,841,536

G

DEP domain containing 5, GATOR1 subcomplex subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936755:871,935...1,024,538
Ensembl chrNW_004936755:872,815...1,024,057

G

dihydrofolate reductase

ClinVar Annotator: match by term: Hepatocellular cancer

NCBI chrNW_004936469:67,962...83,116

G

dicer 1, ribonuclease III

susceptibility

associated with hepatitis B; DNA:SNP: :rs1057035 T>C (human)

NCBI chrNW_004936846:528,768...584,599
Ensembl chrNW_004936846:532,972...575,689

G

divergent protein kinase domain 2B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936502:11,243,167...11,284,186
Ensembl chrNW_004936502:11,247,775...11,284,186

G

DIRAS family GTPase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936591:3,688,774...3,691,342

G

DLG associated protein 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936697:8,001...20,724

G

delta like non-canonical Notch ligand 1

mRNA:increased expression:liver (mouse)

NCBI chrNW_004936604:4,504,519...4,511,897
Ensembl chrNW_004936604:4,504,503...4,511,910

G

dimethylglycine dehydrogenase

disease_progression

associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human)

NCBI chrNW_004936549:6,838,773...6,899,961
Ensembl chrNW_004936549:6,839,295...6,899,911

G

DnaJ heat shock protein family (Hsp40) member C6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936692:2,788,477...2,836,094
Ensembl chrNW_004936692:2,741,632...2,834,078

G

deoxyribonuclease 1L3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:8,430,235...8,495,170
Ensembl chrNW_004936473:8,430,231...8,457,469

G

DNA methyltransferase 1

mRNA, protein:increased expression:liver

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

DNA methyltransferase 3 alpha

protein:increased expression:liver:
mRNA, protein:increased expression:liver

PMID:11844796 PMID:15885882

RGD:2289670 RGD:9588598

NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610

G

DNA methyltransferase 3 beta

mRNA, protein:increased expression:liver
mRNA:increased expression:liver:

PMID:11844796 PMID:15885882

RGD:2289670 RGD:9588598

NCBI chrNW_004936485:19,547,836...19,570,716

G

dihydropyrimidine dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936537:1,660,461...2,439,305
Ensembl chrNW_004936537:1,660,477...2,439,273

G

DSN1 component of MIS12 kinetochore complex

disease_progression

NCBI chrNW_004936561:4,322,709...4,337,405
Ensembl chrNW_004936561:4,322,675...4,337,506

G

denticleless E3 ubiquitin protein ligase homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936557:1,347,991...1,389,836
Ensembl chrNW_004936557:1,347,991...1,389,836

G

dynein light chain roadblock-type 1

NCBI chrNW_004936561:6,118,849...6,135,001

G

dynein light chain roadblock-type 2

NCBI chrNW_004936475:28,286,434...28,295,345
Ensembl chrNW_004936475:28,286,390...28,296,001

G

E2F transcription factor 1

CTD Direct Evidence: marker/mechanism

PMID:12029619 PMID:15565109 PMID:28284560

NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026

G

E2F transcription factor 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936654:322,863...339,365
Ensembl chrNW_004936654:322,863...338,699

G

ELL associated factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936536:8,213,794...8,257,595
Ensembl chrNW_004936536:8,213,763...8,258,201

G

extracellular matrix protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:750,423...756,765
Ensembl chrNW_004936580:750,736...756,771

G

epithelial cell transforming 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936703:5,744...45,636

G

eukaryotic translation elongation factor 2

exacerbates

protein:increased expression, increased phosphorylation:liver (human)

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

EGF containing fibulin extracellular matrix protein 1

disease_progression

protein:decreased expression:liver:

NCBI chrNW_004936491:2,159,654...2,214,480
Ensembl chrNW_004936491:2,159,096...2,214,677

G

elongation factor Tu GTP binding domain containing 2

ameliorates
severity

NCBI chrNW_004936541:1,216,584...1,259,355
Ensembl chrNW_004936541:1,217,138...1,257,935

G

epidermal growth factor

susceptibility

CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human)
associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human)

PMID:9029167 PMID:18167406 PMID:23790025

RGD:14695013 RGD:14695014

NCBI chrNW_004936563:1,058,803...1,181,393

G

epidermal growth factor receptor

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:9029167 PMID:11355950

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

early growth response 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749

G

early growth response 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936753:1,958,250...1,962,640
Ensembl chrNW_004936753:1,958,264...1,962,640

G

EH domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:1,864,836...1,896,079
Ensembl chrNW_004936493:1,864,755...1,896,097

G

eukaryotic translation initiation factor 3 subunit H

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:29,509,154...29,606,124
Ensembl chrNW_004936470:29,509,151...29,606,124

G

ENAH actin regulator

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936526:2,332,344...2,477,827
Ensembl chrNW_004936526:2,332,664...2,477,833

G

endoglin

protein:increased expression:liver (rat)

NCBI chrNW_004936487:15,467,165...15,499,180
Ensembl chrNW_004936487:15,467,835...15,477,488

G

enolase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183

G

E1A binding protein p300

protein:increased expression:liver (rat)

NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138

G

endothelial PAS domain protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936508:5,855,748...5,938,879
Ensembl chrNW_004936508:5,855,732...5,938,856

G

epithelial cell adhesion molecule

severity

protein:increased expression:liver

NCBI chrNW_004936508:5,019,513...5,032,610
Ensembl chrNW_004936508:5,019,918...5,032,414

G

EPH receptor B1

protein:increased phosphorylation:liver (mouse)

NCBI chrNW_004936529:8,006,780...8,261,923
Ensembl chrNW_004936529:7,839,768...8,261,942

G

epoxide hydrolase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286

G

erythropoietin

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936543:742,722...745,332
Ensembl chrNW_004936543:743,537...745,343

G

EPS8 signaling adaptor L3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936704:1,241,341...1,251,702

G

erb-b2 receptor tyrosine kinase 3

disease_progression

NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297

G

erb-b2 receptor tyrosine kinase 4

DNA:insertion/deletion:3'UTR:rs6147150 (human)

NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035

G

ERCC excision repair 1, endonuclease non-catalytic subunit

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745

G

ERCC excision repair 2, TFIIH core complex helicase subunit

disease_progression
susceptibility

DNA:SNP:cd: 312A>G (human)
DNA:SNPs:exon 23: p.K751Q (rs13181) (human)
DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNPs:exon 23: p.K751Q (human)

PMID:19919686 PMID:25531380 PMID:28598207 PMID:28927037

RGD:150530503 RGD:25671459 RGD:25671460 RGD:25671461

NCBI chrNW_004936706:1,816,561...1,829,638
Ensembl chrNW_004936706:1,816,571...1,829,692

G

epiregulin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936598:1,328,803...1,336,141
Ensembl chrNW_004936598:1,328,803...1,344,360

G

endoplasmic reticulum to nucleus signaling 1

DNA:hypomethylation: CpG islands:

NCBI chrNW_004936541:4,613,197...4,705,911
Ensembl chrNW_004936541:4,617,555...4,705,866

G

endoplasmic reticulum protein 29

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936558:4,531,397...4,538,943
Ensembl chrNW_004936558:4,531,471...4,538,943

G

endothelial cell specific molecule 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936480:12,750,732...12,758,262
Ensembl chrNW_004936480:12,750,731...12,758,286

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:19363144 PMID:28284560

NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171

G

electron transfer flavoprotein subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:35,868,851...35,942,662
Ensembl chrNW_004936471:35,868,757...35,943,139

G

exonuclease 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936526:8,570,488...8,627,004

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

susceptibility

mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)
DNA:SNPs: :multiple

PMID:24040354 PMID:24211739 PMID:25226601 PMID:26517514 PMID:28284560 More...

RGD:10755339 RGD:11537550 RGD:126779595 RGD:126779608

NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939

G

coagulation factor II, thrombin

severity

CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;protein:altered expression, altered processing:liver (human)

PMID:2821104 PMID:7620113

NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650

G

fatty acid binding protein 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936656:2,881,552...2,886,192

G

family with sequence similarity 180 member A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936592:501,764...514,153
Ensembl chrNW_004936592:500,440...514,238

G

family with sequence similarity 83 member D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936561:2,528,463...2,549,665
Ensembl chrNW_004936561:2,528,404...2,549,711

G

FA complementation group D2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:3,162,177...3,220,468
Ensembl chrNW_004936602:3,161,960...3,209,868

G

FA complementation group I

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:15,096,215...15,179,856
Ensembl chrNW_004936483:15,106,902...15,179,094

G

Fas cell surface death receptor

treatment

protein:increased expression:liver:

PMID:11274632 PMID:29634416 PMID:30737368

RGD:13792608 RGD:14700677 RGD:14700700

NCBI chrNW_004936735:209,369...234,582

G

Fas ligand

protein:increased expression:liver:

NCBI chrNW_004936481:14,789,547...14,795,780

G

fatty acid synthase

CTD Direct Evidence: marker/mechanism

PMID:14563831 PMID:15543204 PMID:21147110

NCBI chrNW_004936594:5,591,785...5,609,886
Ensembl chrNW_004936594:5,592,609...5,608,972

G

FAT atypical cadherin 1

disease_progression

mRNA,protein:increased expression:liver (human)

NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823

G

fetal and adult testis expressed 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936714:1,029,390...1,036,254

G

fructose-bisphosphatase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936626:3,555,835...3,581,651
Ensembl chrNW_004936626:3,555,762...3,581,659

G

F-box and leucine rich repeat protein 18

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936765:679,643...721,379
Ensembl chrNW_004936765:679,554...721,411

G

F-box protein 11

ameliorates
exacerbates

mRNA:increased expression:liver (human)
protein:increased expression:liver (human)

PMID:29518611 PMID:29603830 PMID:32657545

RGD:152025259 RGD:152025263 RGD:152025266

NCBI chrNW_004936508:4,622,695...4,708,694
Ensembl chrNW_004936508:4,685,595...4,708,694

G

ficolin 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,680,166...11,685,214

G

farnesyl-diphosphate farnesyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936628:3,599,435...3,600,061

G

FES proto-oncogene, tyrosine kinase

exacerbates

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936483:16,123,938...16,135,044
Ensembl chrNW_004936483:16,123,779...16,135,044

G

fibroblast growth factor 19

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:923,943...932,428
Ensembl chrNW_004936599:923,943...932,321

G

fibroblast growth factor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:868,634...875,464
Ensembl chrNW_004936599:868,634...875,464

G

fibroblast growth factor 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:894,091...895,676

G

fibroblast growth factor receptor 1

treatment

CTD Direct Evidence: marker/mechanism

PMID:16452204 PMID:20155451 PMID:21573021 PMID:36029209

RGD:25330358 RGD:25440476 RGD:25440478

NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508

G

fibroblast growth factor receptor 2

severity

associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human)

NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019

G

fibroblast growth factor receptor 4

treatment

NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758

G

fumarate hydratase

ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:10896297 PMID:15221078 PMID:16876016 PMID:17182618 PMID:18313410 More...

NCBI chrNW_004936526:8,936,096...8,965,155
Ensembl chrNW_004936526:8,935,991...8,965,367

G

fragile histidine triad diadenosine triphosphatase

NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506

G

fms related receptor tyrosine kinase 3

ameliorates

human cells in mouse model

NCBI chrNW_004936472:23,169,967...23,239,178
Ensembl chrNW_004936472:23,170,470...23,256,904

G

FLVCR choline and heme transporter 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936557:693,445...727,166
Ensembl chrNW_004936557:692,489...726,965

G

Fos proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

PMID:9029167 PMID:28284560

NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122

G

FosB proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936706:1,900,954...1,907,567
Ensembl chrNW_004936706:1,900,931...1,906,772

G

FOS like 2, AP-1 transcription factor subunit

mRNA:increased expression:liver (human)

PMID:30086463 PMID:32048611

RGD:153344517 RGD:153344521

NCBI chrNW_004936493:4,308,683...4,327,102
Ensembl chrNW_004936493:4,304,395...4,327,179

G

forkhead box A1

susceptibility
sexual_dimorphism
disease_progression

DNA:VNTR, SNPs, haplotypes:multiple:
protein:decreased expression:liver

PMID:25965836 PMID:29208003 PMID:31400761

RGD:11054501 RGD:151665752 RGD:151665820

NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224

G

forkhead box M1

CTD Direct Evidence: marker/mechanism
OMIM:114550

PMID:15082532 PMID:17173139 PMID:28284560

NCBI chrNW_004936606:3,185,289...3,198,427
Ensembl chrNW_004936606:3,185,982...3,198,378

G

forkhead box O1

mRNA:decreased expression:liver

NCBI chrNW_004936565:5,210,014...5,299,213
Ensembl chrNW_004936565:5,210,014...5,302,436

G

forkhead box P1

treatment

NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324

G

forkhead box P3

protein:increased expression:liver

NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308

G

follistatin

CTD Direct Evidence: marker/mechanism

PMID:12203361 PMID:19363144

NCBI chrNW_004936480:13,990,967...13,997,248
Ensembl chrNW_004936480:13,990,929...13,997,248

G

ferritin heavy chain 1

mRNA:increased expression:liver (rat)

NCBI chrNW_004936581:1,118,905...1,120,592

G

far upstream element binding protein 1

ameliorates
exacerbates

human cell line in a mouse model
associated with Chronic Hepatitis C;mRNA:increased expression:liver (human)

PMID:19637194 PMID:25995247 PMID:31587040

RGD:151361188 RGD:151361194 RGD:151361196

NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942

G

glucose-6-phosphatase catalytic subunit 1

treatment

associated with Glycogen Storage Disease IA, human gene in a mouse model

NCBI chrNW_004936490:17,605,865...17,614,754
Ensembl chrNW_004936490:17,605,865...17,615,145

G

glucose-6-phosphate dehydrogenase

disease_progression

mRNA:increased expression:liver (human)

PMID:25473368 PMID:35693827

RGD:10449118 RGD:153344586

NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889

G

gamma-aminobutyric acid type A receptor subunit delta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936737:1,400,437...1,405,885
Ensembl chrNW_004936737:1,400,395...1,406,119

G

glyceraldehyde-3-phosphate dehydrogenase

CTD Direct Evidence: marker/mechanism

PMID:16767786 PMID:21472284

NCBI chrNW_004936709:1,243,149...1,247,782
Ensembl chrNW_004936709:1,243,147...1,247,903

G

GC vitamin D binding protein

susceptibility

protein:increased expression:liver
associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human)

PMID:21683810 PMID:25541958

RGD:14402025 RGD:5509919

NCBI chrNW_004936598:3,220,029...3,256,091
Ensembl chrNW_004936598:3,219,991...3,261,629

G

growth differentiation factor 15

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:2,854,620...2,857,018
Ensembl chrNW_004936596:2,854,841...2,857,111

G

growth differentiation factor 2

CTD Direct Evidence: marker/mechanism

PMID:23936038 PMID:28284560

NCBI chrNW_004936554:7,307,461...7,322,048
Ensembl chrNW_004936554:7,316,435...7,322,060

G

gamma-glutamyltransferase 1

disease_progression

RNA,protein:increased expression, activity:liver:
HBV associated

PMID:10572675 PMID:11940314 PMID:27793641

RGD:14701040 RGD:14701041 RGD:14701048

NCBI chrNW_004936619:762,278...791,610

G

growth hormone receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936518:235,996...380,225
Ensembl chrNW_004936518:235,990...380,272

G

GINS complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936620:421,845...446,853
Ensembl chrNW_004936620:422,230...446,753

G

gap junction protein beta 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936762:389,655...398,035
Ensembl chrNW_004936762:389,669...395,898

G

gap junction protein beta 2

DNA, mRNA:promoter hypermethylation, decreased expression:liver

NCBI chrNW_004936720:1,528,205...1,530,296
Ensembl chrNW_004936720:1,528,249...1,528,929

G

GLI family zinc finger 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936646:1,622,308...1,629,787
Ensembl chrNW_004936646:1,622,308...1,629,779

G

glutamate-ammonia ligase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936481:7,293,301...7,301,416
Ensembl chrNW_004936481:7,293,091...7,306,202

G

geminin DNA replication inhibitor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936671:1,017,621...1,027,224
Ensembl chrNW_004936671:1,018,124...1,026,968

G

guanine monophosphate synthase

protein:increased activity:hepatoma (rat)

NCBI chrNW_004936519:3,094,763...3,143,322
Ensembl chrNW_004936519:3,104,701...3,141,549

G

G protein subunit alpha o1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:8,610,123...8,681,606
Ensembl chrNW_004936475:8,565,889...8,690,673

G

G protein subunit alpha z

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936619:191,097...244,034
Ensembl chrNW_004936619:191,091...244,235

G

glycine N-methyltransferase

CTD Direct Evidence: marker/mechanism
OMIM:114550

PMID:19146867 PMID:31086990

NCBI chrNW_004936476:16,961,734...16,965,487
Ensembl chrNW_004936476:16,957,270...16,965,346

G

golgi membrane protein 1

severity

protein:increased expression:serum
mRNA, protein:increased expression:liver

PMID:21140449 PMID:21443671

RGD:401827118 RGD:401827119

NCBI chrNW_004936680:1,463,991...1,528,322

G

glypican 1

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936745:1,118,732...1,127,169

G

glypican 3

severity
exacerbates
disease_progression
treatment

protein:increased expression:liver
protein:increased expression:liver (human)
protein:increased expression:blood serum (human)
mRNA:increased expression:Peripheral Blood (human)
mRNA,protein:increased expression:peripheral blood mononuclear cell,blood serum, liver (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum

PMID:16698587 PMID:19496787 PMID:21438004 PMID:22883669 PMID:23558072 More...

RGD:14695019 RGD:14695020 RGD:243065125 RGD:243065131 RGD:243065134 RGD:243065135 RGD:243065139

NCBI chrNW_004936691:1,060,013...1,459,736
Ensembl chrNW_004936691:1,059,994...1,459,740

G

glycoprotein M6A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936516:6,339,058...6,647,412
Ensembl chrNW_004936516:6,338,819...6,481,425

G

G protein-coupled receptor 158

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936484:835,886...1,224,450
Ensembl chrNW_004936484:836,700...1,226,162

G

G protein-coupled receptor 182

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936646:1,210,711...1,212,746
Ensembl chrNW_004936646:1,210,757...1,212,425

G

glutathione peroxidase 1

no_association
susceptibility
severity

DNA:missense mutation:CDS:p.P198L (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:CDS:p.P198L (human)
associated with hepatitis C;DNA:missense mutation:CDS:p.P198L (rs1050450) (human)

PMID:16510607 PMID:19929244 PMID:25894370 PMID:26990426

RGD:11533013 RGD:151708729 RGD:152995483 RGD:152998906

NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987

G

glutathione peroxidase 3

disease_progression
severity

DNA:hypermethylation
mRNA,protein:decreased expression:liver, blood plasma (human)

PMID:25333265 PMID:25445749 PMID:27570561

RGD:151665355 RGD:151665509 RGD:401827855

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

growth factor receptor bound protein 7

exacerbates

protein:increased expression:liver (human)

NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337

G

glutathione S-transferase pi 1

CTD Direct Evidence: marker/mechanism
DNA:increased methylation:promoter

PMID:9029167 PMID:22536438

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

G2 and S-phase expressed 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936629:3,590,101...3,607,625
Ensembl chrNW_004936629:3,592,100...3,607,754

G

glycogen synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936548:5,256,185...5,309,758
Ensembl chrNW_004936548:5,256,437...5,309,758

G

hepcidin antimicrobial peptide

mRNA:decreased expression:liver (human)
CTD Direct Evidence: marker/mechanism
DNA:hypermethylation,hypomethylation:promoter

PMID:28284560 PMID:29235098

NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686

G

hydroxyacid oxidase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936627:4,167,501...4,179,596
Ensembl chrNW_004936627:4,159,214...4,179,806

G

hepatitis A virus cellular receptor 1

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936515:6,030,402...6,051,161

G

hepatitis A virus cellular receptor 2

disease_progression

associated with hepatitis B;DNA:SNP: : ��1516 G>T (human)

NCBI chrNW_004936515:6,001,324...6,015,407

G

histone deacetylase 2

disease_progression

mRNA:increased expression:liver:

NCBI chrNW_004936679:2,448,676...2,474,641
Ensembl chrNW_004936679:2,448,390...2,474,641

G

histone deacetylase 4

mRNA:increased expression:liver:

NCBI chrNW_004936745:1,730,743...1,942,071
Ensembl chrNW_004936745:1,730,694...1,942,074

G

HECT and RLD domain containing E3 ubiquitin protein ligase 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936685:917,019...966,814

G

homeostatic iron regulator

disease_progression

associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human)

PMID:20019189 PMID:29642405

RGD:14746967 RGD:2317357

NCBI chrNW_004936671:1,940,079...1,947,574
Ensembl chrNW_004936671:1,940,101...1,947,580

G

hepatocyte growth factor

CTD Direct Evidence: marker/mechanism

PMID:9932610 PMID:11896611

NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779

G

HGF activator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:20,291,791...20,298,764
Ensembl chrNW_004936477:20,291,852...20,298,764

G

hedgehog interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936535:4,210,305...4,305,930
Ensembl chrNW_004936535:4,210,305...4,305,930

G

hypoxia inducible factor 1 subunit alpha

treatment
disease_progression

protein:increased expression:liver (human)

PMID:19335982 PMID:26078356 PMID:31321740

RGD:11526468 RGD:155882550 RGD:9068886

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

hypoxia inducible lipid droplet associated

disease_progression

mRNA, protein:increased expression:liver (human)
human cells in mouse model
mRNA:increased expression:liver (human)

PMID:30205391 PMID:31142329 PMID:35693827

RGD:153344574 RGD:153344577 RGD:153344586

NCBI chrNW_004936479:15,582,260...15,583,213
Ensembl chrNW_004936479:15,582,260...15,607,428

G

Holliday junction recognition protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936525:3,528,379...3,544,088

G

high mobility group box 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936516:4,536,664...4,539,331
Ensembl chrNW_004936516:4,534,306...4,539,387

G

3-hydroxy-3-methylglutaryl-CoA reductase

CTD Direct Evidence: marker/mechanism

PMID:9207284 PMID:21147110

NCBI chrNW_004936549:1,378,536...1,400,501
Ensembl chrNW_004936549:1,378,736...1,400,532

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

disease_progression

NCBI chrNW_004936627:4,451,847...4,473,163
Ensembl chrNW_004936627:4,451,823...4,473,223

G

hyaluronan mediated motility receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936515:570,112...599,400
Ensembl chrNW_004936515:571,139...600,132

G

HNF1 homeobox A

treatment

human cell line in mouse model

NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505

G

hepatocyte nuclear factor 4 alpha

protein:decreased expression:liver:

NCBI chrNW_004936530:2,401,053...2,425,989
Ensembl chrNW_004936530:2,401,043...2,454,466

G

heterogeneous nuclear ribonucleoprotein A1

protein:increased expression:liver (human)

NCBI chrNW_004936512:11,481,017...11,487,737

G

heterogeneous nuclear ribonucleoprotein A2/B1

mRNA:increased expression:liver (rat)
protein:increased expression:liver (human)

PMID:20604928 PMID:23633480

RGD:9685422 RGD:9685423

NCBI chrNW_004936478:2,970,261...2,980,277
Ensembl chrNW_004936478:2,970,468...2,980,381

G

heterogeneous nuclear ribonucleoprotein A/B

severity

mRNA:increased expression:liver (human)

NCBI chrNW_004936647:478,445...520,361
Ensembl chrNW_004936647:478,443...484,570

G

heterogeneous nuclear ribonucleoprotein D

protein:increased expression:liver (rat)
protein:increased expression:liver (human)

PMID:20102719 PMID:22318685

RGD:10042969 RGD:10042977

NCBI chrNW_004936738:2,096,370...2,115,135
Ensembl chrNW_004936738:2,096,370...2,113,604

G

heterogeneous nuclear ribonucleoprotein H1

protein:increased expression:liver (human)

NCBI chrNW_004936739:1,135,282...1,144,643
Ensembl chrNW_004936739:1,135,289...1,144,643

G

heterogeneous nuclear ribonucleoprotein L

associated with Hepatitis B

NCBI chrNW_004936661:1,793,791...1,806,564
Ensembl chrNW_004936661:1,793,801...1,806,579

G

homeobox A10

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:3,798,679...3,802,007

G

homeobox A13

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:3,824,715...3,827,277
Ensembl chrNW_004936478:3,824,715...3,827,277

G

homeobox D9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936509:5,609,744...5,611,943
Ensembl chrNW_004936509:5,609,744...5,611,943

G

hypoxanthine phosphoribosyltransferase 1

protein:increased activity:hepatoma (rat)

NCBI chrNW_004936691:650,753...694,362
Ensembl chrNW_004936691:652,769...694,463

G

HRas proto-oncogene, GTPase

treatment

human cells in a mouse model
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:10791191 PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

heat shock protein family A (Hsp70) member 5

CTD Direct Evidence: marker/mechanism

PMID:21472284 PMID:29698666

NCBI chrNW_004936487:13,348,465...13,352,717
Ensembl chrNW_004936487:13,348,465...13,352,717

G

heat shock protein family A (Hsp70) member 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:7,702,186...7,716,428
Ensembl chrNW_004936531:7,702,695...7,716,380

G

heat shock protein family B (small) member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186

G

HIV-1 Tat interactive protein 2

CTD Direct Evidence: therapeutic

NCBI chrNW_004936654:1,315,921...1,332,926
Ensembl chrNW_004936654:1,315,862...1,333,005

G

HtrA serine peptidase 1

disease_progression
exacerbates

mRNA:decreased expression:liver (human)
protein:decreased expression:liver (human)

PMID:20943460 PMID:26403966

RGD:152985524 RGD:152985529

NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739

G

intercellular adhesion molecule 1

severity

protein:increased expression:serum

NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174

G

isocitrate dehydrogenase (NADP(+)) 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

G

isocitrate dehydrogenase (NADP(+)) 2

disease_progression

NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341

G

immediate early response 2

mRNA, protein:decreased expression:liver (human)

NCBI chrNW_004936659:2,176,962...2,179,900
Ensembl chrNW_004936659:2,178,312...2,178,983

G

interferon gamma

mRNA:increased expression:liver (mouse)

NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452

G

immunoglobulin binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936762:1,292,572...1,319,145

G

insulin like growth factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351

G

insulin like growth factor 1 receptor

susceptibility

DNA:SNPs, haplotype: :
CTD Direct Evidence: marker/mechanism

PMID:17441810 PMID:23958494 PMID:24758241

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

insulin like growth factor 2

susceptibility

associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human)
CTD Direct Evidence: marker/mechanism

PMID:12532445 PMID:16092956 PMID:16750516 PMID:17554210

RGD:14401723 RGD:2311523

NCBI chrNW_004936816:972,902...981,232
Ensembl chrNW_004936816:972,282...979,167

G

insulin like growth factor 2 mRNA binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:12,430,343...12,468,794
Ensembl chrNW_004936490:12,430,008...12,469,083

G

insulin like growth factor 2 mRNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:456,369...595,705
Ensembl chrNW_004936478:458,871...595,742

G

insulin like growth factor 2 receptor

no_association
treatment
disease_progression

ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:loss of heterozygosity,mutations:liver:
DNA:loss of heterozygosity:liver

OMIM
ClinVar
RGD

PMID:9722161 PMID:10347113 PMID:18322954 PMID:25741868 PMID:30720132

RGD:14985219 RGD:14985220 RGD:14985221

NCBI chrNW_004936489:11,447,043...11,523,695
Ensembl chrNW_004936489:11,447,038...11,524,174

G

insulin like growth factor binding protein acid labile subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:2,205,294...2,207,343
Ensembl chrNW_004936694:2,204,182...2,207,328

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

treatment

protein:decreased expression:liver (human)

PMID:17292824 PMID:22176836 PMID:22922425 PMID:24971483 PMID:25173965 More...

RGD:11079569 RGD:153297807 RGD:153297813 RGD:153305943 RGD:153305945 RGD:153305947

NCBI chrNW_004936809:1,280,254...1,306,964
Ensembl chrNW_004936809:1,257,654...1,301,813

G

IKAROS family zinc finger 1

ameliorates

protein:increased expression:liver (human)

NCBI chrNW_004936686:1,459,582...1,556,478
Ensembl chrNW_004936686:1,462,145...1,556,451

G

interleukin 10

treatment

PMID:23822114 PMID:26890368

RGD:14975171 RGD:7365006

NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502

G

interleukin 12A

susceptibility

associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human)

PMID:20521253 PMID:26631030 PMID:27819525

RGD:25440490 RGD:25440491 RGD:25440501

NCBI chrNW_004936519:6,166,060...6,180,652
Ensembl chrNW_004936519:6,175,261...6,180,396

G

interleukin 15 receptor subunit alpha

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936484:8,590,945...8,623,478
Ensembl chrNW_004936484:8,590,482...8,623,469

G

interleukin 18

susceptibility
disease_progression
severity

DNA:SNP:promoter:-137G>C(rs187238)(human)
associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)
associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)

PMID:26893476 PMID:27429592 PMID:27470888 PMID:29341496

RGD:11538094 RGD:14695526 RGD:14695540 RGD:14696663

NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189

G

interleukin 18 receptor 1

mRNA:decreased expression:liver

NCBI chrNW_004936713:1,038,985...1,075,770
Ensembl chrNW_004936713:1,038,877...1,075,811

G

interleukin 1 beta

susceptibility

DNA:polymorphism:promoter:-31T>C (human)

NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165

G

interleukin 1 receptor accessory protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004937049:48,267...185,766
Ensembl chrNW_004937049:48,274...181,281

G

interleukin 1 receptor antagonist

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340

G

interleukin 2

treatment

PMID:9449371 PMID:10933975

RGD:14747035 RGD:8693323

NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625

G

interleukin 21

associated with hepatitis B;DNA:SNPS, haplotype:(rs13143866, rs2221903, rs907715) (human)

NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883

G

interleukin 6

disease_progression
treatment

mRNA,protein:increased expression:liver, blood serum (mouse)
DNA:SNP: :rs2069852 (human)
CTD Direct Evidence: marker/mechanism

PMID:17615358 PMID:20818158 PMID:26297436 PMID:26569409 PMID:27022031 More...

RGD:11344640 RGD:127285672 RGD:14975289

NCBI chrNW_004936549:7,015,595...7,016,246

G

interleukin 6 cytokine family signal transducer

NCBI chrNW_004936480:11,867,573...11,913,563
Ensembl chrNW_004936480:11,884,582...11,909,635

G

inhibitor of growth family member 3

treatment

NCBI chrNW_004936605:4,154,276...4,179,627
Ensembl chrNW_004936605:4,151,202...4,179,689

G

indolethylamine N-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:6,997,605...7,002,649
Ensembl chrNW_004936478:6,997,549...7,002,666

G

inositol polyphosphate-4-phosphatase type II B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936535:5,427,131...6,168,622
Ensembl chrNW_004936535:5,794,135...6,171,072

G

insulin

associated with Chronic Hepatitis C;mRNA:decreased expression:liver (human)

NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357

G

insulin receptor

mRNA, protein:increased expression:liver (human, rat)
human cells in a mouse model

PMID:23633480 PMID:29610518

RGD:14700930 RGD:9685423

NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668

G

IQ motif containing GTPase activating protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:16,489,127...16,594,712
Ensembl chrNW_004936483:16,489,133...16,594,783

G

IQ motif containing GTPase activating protein 2

CTD Direct Evidence: marker/mechanism
OMIM:114550

NCBI chrNW_004936549:256,097...541,860
Ensembl chrNW_004936549:255,303...541,917

G

IQ motif containing GTPase activating protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:5,712,118...5,751,721
Ensembl chrNW_004936580:5,713,156...5,751,721

G

interferon regulatory factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936554:4,706,688...4,793,236
Ensembl chrNW_004936554:4,706,650...4,793,701

G

insulin receptor substrate 1

CTD Direct Evidence: marker/mechanism

PMID:1311924 PMID:23958494

NCBI chrNW_004936525:9,064,442...9,125,972
Ensembl chrNW_004936525:9,064,466...9,122,635

G

insulin receptor substrate 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:2,772,187...2,796,398

G

ISG15 ubiquitin like modifier

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936737:2,043,383...2,044,761

G

inter-alpha-trypsin inhibitor heavy chain 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:3,553,210...3,568,636
Ensembl chrNW_004936473:3,553,210...3,568,636

G

inter-alpha-trypsin inhibitor heavy chain 4

disease_progression

associated with hepatitis B;protein:decreased expression:serum

NCBI chrNW_004936473:3,573,282...3,589,345
Ensembl chrNW_004936473:3,573,384...3,589,345

G

jagged canonical Notch ligand 1

protein:increased expression:liver

NCBI chrNW_004936485:8,857,688...8,894,270
Ensembl chrNW_004936485:8,857,669...8,895,315

G

Janus kinase 1

NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132

G

Janus kinase 2

ameliorates
severity
treatment
exacerbates

L-JAK2 KO
mRNA:decreased expression:liver (human)
protein:increased phosphorylation:liver (mouse)
associated with Diseases of the Aged and non-alcoholic fatty liver disease
protein:increased phosphorylation:liver (human)

PMID:22392353 PMID:22821478 PMID:25420511 PMID:28100771 PMID:29486150 More...

RGD:125097525 RGD:127285621 RGD:127285655 RGD:127285672 RGD:127285675 RGD:18182928

NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867

G

Jun dimerization protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936488:4,523,879...4,553,028
Ensembl chrNW_004936488:4,523,888...4,553,117

G

Jun proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350

G

lysine acetyltransferase 2B

severity

protein:decreased expression:liver (human)

NCBI chrNW_004936473:12,341,545...12,415,637
Ensembl chrNW_004936473:12,344,343...12,417,875

G

kelch repeat and BTB domain containing 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936615:1,120,512...1,127,488
Ensembl chrNW_004936615:1,130,826...1,132,754

G

potassium voltage-gated channel subfamily H member 1

protein:increased expression:liver (human)

NCBI chrNW_004936557:2,133,596...2,493,170
Ensembl chrNW_004936557:2,133,564...2,493,155

G

potassium calcium-activated channel subfamily N member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004937043:133,981...269,593

G

lysine demethylase 1A

severity

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092

G

lysine demethylase 3A

mRNA:increased expression:liver (human)

NCBI chrNW_004936712:1,053,210...1,097,845
Ensembl chrNW_004936712:1,053,210...1,096,961

G

lysine demethylase 5C

exacerbates

protein:increased expression:liver (human)

NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966

G

lysine demethylase 6A

ameliorates

human cells in a mouse model

NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163

G

lysine demethylase 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936501:10,932,541...10,955,772
Ensembl chrNW_004936501:10,933,671...10,951,707

G

kinase insert domain receptor

treatment
disease_progression

protein:decreased expression:liver
associated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human)
DNA:SNPs: :rs1870377, rs2071559, rs2305948 (human)
protein:increased expression:liver

PMID:19177438 PMID:23660204 PMID:24445728 PMID:25182707 PMID:25333267

RGD:126848806 RGD:126848810 RGD:126848812 RGD:126848813 RGD:126848814

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

kinesin family member 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:2,163,316...2,213,674
Ensembl chrNW_004936601:2,163,795...2,213,588

G

kinesin family member 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936567:3,704,672...3,764,111

G

kinesin family member 15

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936695:861,324...919,368
Ensembl chrNW_004936695:861,550...919,368

G

kinesin family member 18A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936533:9,173,739...9,242,928
Ensembl chrNW_004936533:9,173,715...9,239,931

G

kinesin family member 18B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936541:1,285,137...1,304,179
Ensembl chrNW_004936541:1,285,661...1,295,458

G

kinesin family member 1B

susceptibility
severity

DNA:snp:intron:c.2537+518A>G (rs17401966) (human)
mRNA, protein:decreased expression:liver (human)

PMID:26217094 PMID:27122668

RGD:11052488 RGD:12738461

NCBI chrNW_004936623:4,091,093...4,222,510
Ensembl chrNW_004936623:4,091,190...4,218,251

G

kinesin family member 20A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:7,361,928...7,371,397
Ensembl chrNW_004936531:7,361,928...7,374,789

G

kinesin family member 23

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:29,154,618...29,177,865
Ensembl chrNW_004936471:29,150,205...29,177,769

G

kinesin family member 2C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:25,967,095...26,000,678
Ensembl chrNW_004936474:25,978,707...26,000,140

G

kinesin family member 4A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936762:1,062,570...1,194,192
Ensembl chrNW_004936762:1,061,526...1,187,863

G

kinesin family member C1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:25,488,426...25,503,135
Ensembl chrNW_004936476:25,487,503...25,546,359

G

KLF transcription factor 4

disease_progression
treatment

NCBI chrNW_004936559:5,105,456...5,109,970
Ensembl chrNW_004936559:5,105,463...5,109,970

G

lysine methyltransferase 2A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:3,480,071...3,566,823
Ensembl chrNW_004936542:3,391,774...3,562,147

G

lysine methyltransferase 2B

CTD Direct Evidence: marker/mechanism
DNA:insertions, translocations:intron:IVS3, multiple (human)

PMID:18320596 PMID:22634754

NCBI chrNW_004936570:583,616...605,846
Ensembl chrNW_004936570:583,616...605,603

G

lysine methyltransferase 2C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365

G

KRAS proto-oncogene, GTPase

induced

aflatoxin B1 induced:DNA:transversion,transition mutations:cds:
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver

PMID:8446626 PMID:11286481 PMID:11563603 PMID:29275358

RGD:11568697 RGD:14398750

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

keratin 18

OMIM:114550

NCBI chrNW_004936512:10,290,706...10,294,647
Ensembl chrNW_004936512:10,290,690...10,294,651

G

lecithin-cholesterol acyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248

G

leukocyte cell derived chemotaxin 2

ameliorates

human cells in mouse model
protein:increased expression:blood serum (mouse)
protein:increased expression:blood serum (human)

PMID:21394108 PMID:24892551

RGD:153323333 RGD:153323335

NCBI chrNW_004936597:3,051,143...3,057,383
Ensembl chrNW_004936597:3,051,143...3,057,383

G

leptin

susceptibility
severity

DNA:SNP:enhancer:-2548G>A (rs7799039) (human)
protein:increased expression:liver (human)

PMID:18573568 PMID:28452232

RGD:15039399 RGD:25330348

NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334

G

leptin receptor

susceptibility

associated with Hepatitis B, Chronic;DNA:missense mutations:cds:p.Q223R, p.K109R (human)

NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444

G

leucine zipper and EF-hand containing transmembrane protein 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004936477:21,550,104...21,589,662
Ensembl chrNW_004936477:21,550,013...21,587,007

G

LIF receptor subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936518:3,651,630...3,693,072
Ensembl chrNW_004936518:3,652,152...3,693,078

G

signal transducer and activator of transcription 5B

exacerbates
ameliorates

protein:increased expression:liver (human)
mRNA:increased expression:liver (human)

PMID:17047057 PMID:31485610

RGD:153298929 RGD:153298932

NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941

G

apolipoprotein F

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936646:764,689...766,265

G

HLA class II histocompatibility antigen, DP alpha 1 chain

DNA:hypomethylation: CpG islands:

NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907

G

alpha-2-macroglobulin

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver:

NCBI chrNW_004936870:424,832...468,303
Ensembl chrNW_004936870:424,951...468,167

G

PZP alpha-2-macroglobulin like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936870:497,071...542,364

G

C-C chemokine receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186

G

urocanate hydratase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936898:583,802...600,305
Ensembl chrNW_004936898:584,157...600,305

G

interleukin-8

disease_progression
susceptibility

protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human)
DNA:SNPs, haplotype:multiple

PMID:12432545 PMID:24381110 PMID:26078356 PMID:30523154 PMID:35776891

RGD:11526468 RGD:26884364 RGD:26884366

NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353

G

angiotensin-converting enzyme

susceptibility

CTD Direct Evidence: therapeutic
DNA:insertion/deletion:intron 16:

PMID:16328049 PMID:25208933

NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177

G

cytochrome P450 1A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332

G

cytochrome P450 1A2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484

G

cytochrome c oxidase subunit 7B2, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936482:12,950,597...12,951,029

G

steroid 17-alpha-hydroxylase/17,20 lyase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936600:3,097,620...3,102,713
Ensembl chrNW_004936600:3,097,638...3,102,713

G

neuroendocrine secretory protein 55

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More...

NCBI chrNW_004936530:1,353,432...1,407,437

G

S-methylmethionine--homocysteine S-methyltransferase BHMT2

severity

mRNA:altered expression:liver tumor (human)

NCBI chrNW_004936549:6,900,075...6,914,217
Ensembl chrNW_004936549:6,899,948...6,914,263

G

betaine--homocysteine S-methyltransferase 1

disease_progression

associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human)

NCBI chrNW_004936549:6,938,100...6,956,380
Ensembl chrNW_004936549:6,938,092...6,957,363

G

24-hydroxycholesterol 7-alpha-hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:13,697,598...13,819,362
Ensembl chrNW_004936476:13,697,583...13,819,109

G

cytochrome P450 2E1

associated with alcohol dependence
DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human)
CTD Direct Evidence: marker/mechanism

PMID:15162526 PMID:20364586 PMID:29765251

RGD:14700882 RGD:14700899

NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102

G

cytochrome P450 26B1

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895

G

haptoglobin

protein:increased expression:saliva
protein:decreased expression:liver (human)

PMID:24259486 PMID:31041878

RGD:152995276 RGD:27095881

NCBI chrNW_004936475:21,841,054...21,845,821

G

calmodulin-like protein 3

severity

protein:decreased expression:liver (human)

NCBI chrNW_004936484:8,976,512...8,977,792
Ensembl chrNW_004936484:8,977,252...8,977,701

G

PTTG1 regulator of sister chromatid separation, securin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936841:274,458...275,148

G

insulin

CTD Direct Evidence: marker/mechanism

G

lysyl oxidase like 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936556:745,798...765,926
Ensembl chrNW_004936556:745,798...765,918

G

lysophosphatidic acid receptor 1

NCBI chrNW_004936559:2,187,791...2,331,587
Ensembl chrNW_004936559:2,259,420...2,332,806

G

lecithin retinol acyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936576:1,491,480...1,498,568
Ensembl chrNW_004936576:1,492,297...1,501,917

G

LDL receptor related protein 1B

exacerbates

DNA:mutations:multiple: (human)
protein:increased expression:liver (human)

PMID:33324588 PMID:33391418

RGD:150429776 RGD:150429785

NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283

G

leucine rich repeat containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:7,016,435...7,141,398
Ensembl chrNW_004936476:7,015,891...7,141,564

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More...

NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083

G

leucine rich repeat containing 59

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:11,296,590...11,308,379
Ensembl chrNW_004936490:11,296,530...11,310,946

G

lymphatic vessel endothelial hyaluronan receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936528:7,788,560...7,802,821
Ensembl chrNW_004936528:7,788,352...7,802,902

G

leucine zipper like post translational regulator 1

DNA:missense mutation:cds, liver (human)

NCBI chrNW_004936619:2,505,300...2,523,500
Ensembl chrNW_004936619:2,505,542...2,523,500

G

mitotic arrest deficient 2 like 1

CTD Direct Evidence: marker/mechanism

PMID:28284560 PMID:39316419

NCBI chrNW_004936662:92,421...98,531
Ensembl chrNW_004936662:92,328...99,517

G

mitogen-activated protein kinase kinase 2

exacerbates

mRNA:increased expression:liver (human)
protein:increased expression:liver, cytosol (rat)

PMID:9397988 PMID:33553243

RGD:150530475 RGD:150530477

NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090

G

mitogen-activated protein kinase kinase 4

protein:decreased expression:liver (human)

NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662

G

mitogen-activated protein kinase kinase kinase 1

exacerbates

mRNA:decreased expression:liver (human)

NCBI chrNW_004936480:11,082,811...11,156,691
Ensembl chrNW_004936480:11,083,605...11,156,691

G

mitogen-activated protein kinase kinase kinase 8

ameliorates

NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892

G

mitogen-activated protein kinase kinase kinase kinase 4

ameliorates
severity
treatment

human cell line in a mouse model
human recombinant gene and cell line in a mouse model

PMID:21196414 PMID:27010469 PMID:31922225

RGD:151347673 RGD:151347674 RGD:151347839

NCBI chrNW_004936713:515,388...616,024
Ensembl chrNW_004936713:435,238...612,835

G

mitogen-activated protein kinase 1

protein:increased expression:liver

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

mitogen-activated protein kinase 14

exacerbates
treatment

PMID:23271722 PMID:25216638

RGD:151665347 RGD:151665348

NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232

G

mitogen-activated protein kinase 8

ameliorates

protein:decreased phosphorylation:liver (human)

NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907

G

microtubule associated protein tau

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936541:2,381,411...2,479,984

G

macrophage receptor with collagenous structure

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:51,323,746...51,366,551

G

methionine adenosyltransferase 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936716:126,628...142,986
Ensembl chrNW_004936716:126,574...143,155

G

membrane bound transcription factor peptidase, site 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936641:3,696,506...3,751,558
Ensembl chrNW_004936641:3,696,536...3,751,598

G

membrane bound transcription factor peptidase, site 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936624:2,464,152...2,510,984
Ensembl chrNW_004936624:2,463,909...2,511,158

G

minichromosome maintenance 10 replication initiation factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004937104:132,692...160,965

G

minichromosome maintenance complex component 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936798:756,350...768,600
Ensembl chrNW_004936798:756,588...765,338

G

minichromosome maintenance complex component 7

susceptibility

associated with hepatitis B;miRNA:increased expression:liver (human)
associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human)

PMID:24416400 PMID:27298561

RGD:15042853 RGD:15042885

NCBI chrNW_004936543:238,573...246,746
Ensembl chrNW_004936543:233,960...246,746

G

minichromosome maintenance 9 homologous recombination repair factor

OMIM:114550

NCBI chrNW_004936658:1,657,226...1,734,150

G

MDM2 proto-oncogene

susceptibility

DNA:transversion:promoter:g.-309T>G (human)

NCBI chrNW_004936545:6,709,903...6,732,334

G

malic enzyme 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936510:7,425,983...7,571,090
Ensembl chrNW_004936510:7,426,347...7,571,553

G

methyl-CpG binding protein 2

CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver

PMID:11844796 PMID:26189965

NCBI chrNW_004936809:902,938...967,771
Ensembl chrNW_004936809:911,764...966,839

G

mediator complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,625,201...14,663,184
Ensembl chrNW_004936490:14,625,897...14,657,802

G

maternal embryonic leucine zipper kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:4,479,639...4,544,561
Ensembl chrNW_004936524:4,469,256...4,544,290

G

MET proto-oncogene, receptor tyrosine kinase

severity

protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular cancer

RGD
ClinVar
OMIM

PMID:21774103 PMID:21970370 PMID:22703879 PMID:24728327 PMID:25741868 More...

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

MFSD2 lysolipid transporter A, lysophospholipid

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:21,790,807...21,803,336
Ensembl chrNW_004936474:21,790,747...21,803,360

G

marker of proliferation Ki-67

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936486:15,561,327...15,587,109

G

MLX interacting protein like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:2,839,105...2,856,997
Ensembl chrNW_004936543:2,839,105...2,857,002

G

membrane metalloendopeptidase

NCBI chrNW_004936519:2,513,896...2,595,896
Ensembl chrNW_004936519:2,513,704...2,595,971

G

matrix metallopeptidase 14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611

G

matrix metallopeptidase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

CTD Direct Evidence: marker/mechanism

PMID:20084675 PMID:21681821

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

monoacylglycerol O-acyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936498:4,464,453...4,482,237
Ensembl chrNW_004936498:4,464,427...4,481,509

G

MPL proto-oncogene, thrombopoietin receptor

human cells in mouse model

NCBI chrNW_004936474:24,744,673...24,757,189
Ensembl chrNW_004936474:24,744,673...24,757,085

G

myeloperoxidase

susceptibility
disease_progression

associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human)
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human)
CTD Direct Evidence: marker/mechanism

PMID:19731237 PMID:21907168

RGD:26923907 RGD:27095879

NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070

G

maestro

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:12,468,839...12,482,645
Ensembl chrNW_004936497:12,468,810...12,484,070

G

mutS homolog 3

ClinVar Annotator: match by term: Hepatocellular cancer

NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561

G

mutS homolog 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936727:1,776,038...1,794,152
Ensembl chrNW_004936727:1,777,570...1,793,711

G

MDM2 binding protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:26,312,670...26,386,410
Ensembl chrNW_004936470:26,312,590...26,386,427

G

metadherin

treatment

human cells in a mouse model

NCBI chrNW_004936470:45,016,099...45,079,709
Ensembl chrNW_004936470:45,016,099...45,079,710

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

mRNA:increased expression:liver

NCBI chrNW_004936556:462,998...475,092
Ensembl chrNW_004936556:462,974...475,159

G

methylenetetrahydrofolate reductase

susceptibility
onset
disease_progression

DNA:SNP,haplotype: :677C>T, 1298A>C(human)
DNA:SNPs: :677C>T, 1298A>C(human)
DNA:SNP: :1298A>C(human)
DNA:SNP: :677C>T(human)

PMID:17503006 PMID:17659576 PMID:19035314 PMID:23996892

RGD:14696703 RGD:14696704 RGD:14696707 RGD:14696708

NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193

G

mechanistic target of rapamycin kinase

severity

CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human)

PMID:21147110 PMID:25371154

NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342

G

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

susceptibility

DNA:SNP: :66A>G(human)

NCBI chrNW_004936643:379,790...410,034
Ensembl chrNW_004936643:380,968...409,464

G

mevalonate kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936769:1,274,595...1,295,186
Ensembl chrNW_004936769:1,274,540...1,298,178

G

MYB proto-oncogene like 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936530:2,918,924...2,953,467
Ensembl chrNW_004936530:2,918,951...2,953,467

G

MYC proto-oncogene, bHLH transcription factor

severity
treatment

OMIM:114550
mRNA:increased expression:liver (rat)
mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism

MouseDO
RGD
CTD

PMID:9029167 PMID:12029619 PMID:15565109 PMID:21644509 PMID:22076107 More...

RGD:6903288 RGD:7240567 RGD:7240695 RGD:7241004

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

MYD88 innate immune signal transduction adaptor

exacerbates
treatment
ameliorates

human gene and cell in a mouse model
mouse cell line in a mouse model
protein:increased expression:liver (human)
human cell line in a mouse model
protein, mRNA:decreased expression:liver (human)
mRNA:increased expression:liver (human)

PMID:17615358 PMID:24603331 PMID:26985932 PMID:28370778 PMID:29022910 More...

RGD:150520022 RGD:150520169 RGD:150521532 RGD:150521534 RGD:150524327 RGD:150524329 RGD:150524330 RGD:150524334 RGD:150530285

NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372

G

nibrin

ClinVar Annotator: match by term: Hepatocellular cancer

PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More...

NCBI chrNW_004936544:3,773,828...3,812,673
Ensembl chrNW_004936544:3,775,220...3,808,837

G

non-SMC condensin I complex subunit G

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:10,408,347...10,445,361
Ensembl chrNW_004936477:10,405,997...10,445,206

G

non-SMC condensin I complex subunit H

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936744:440,958...468,964
Ensembl chrNW_004936744:440,956...468,972

G

nuclear receptor coactivator 2

exacerbates

PMID:22556267 PMID:28273073

RGD:153002573 RGD:153002576

NCBI chrNW_004936496:14,844,923...15,102,922
Ensembl chrNW_004936496:14,844,855...15,016,454

G

NDC80 kinetochore complex component

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936672:1,872,205...1,910,956
Ensembl chrNW_004936672:1,872,193...1,909,675

G

nei like DNA glycosylase 3

disease_progression

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)

PMID:28284560 PMID:35693827

NCBI chrNW_004936516:7,739,191...7,781,735
Ensembl chrNW_004936516:7,739,157...7,782,024

G

NIMA related kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936557:1,683,027...1,695,410
Ensembl chrNW_004936557:1,682,984...1,695,414

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

disease_progression

protein:decreased expression:liver
DNA, protein:SNP, increased expression:intron, liver

PMID:26443326 PMID:27289045 PMID:29130106

RGD:11076529 RGD:150530489 RGD:150530504

NCBI chrNW_004936657:3,536,212...3,622,999
Ensembl chrNW_004936657:3,536,141...3,623,821

G

NFE2 like bZIP transcription factor 1

OMIM:114550

NCBI chrNW_004936490:13,265,269...13,279,164
Ensembl chrNW_004936490:13,266,347...13,279,206

G

NFE2 like bZIP transcription factor 2

CTD Direct Evidence: marker/mechanism

PMID:22561517 PMID:31546024

NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262

G

nuclear factor kappa B subunit 1

disease_progression
treatment

associated with Chronic Hepatitis B;DNA:insertion/deletion:3'utr: -94ins/delATTG (rs28720239) (human)

PMID:19797428 PMID:25999787

RGD:152177911 RGD:40400751

NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435

G

NFKB inhibitor alpha

susceptibility
disease_progression

associated with hepatitis B;DNA:SNP:promoter:-826C>T (rs2233406) (human)
CTD Direct Evidence: therapeutic
associated with Chronic Hepatitis B;DNA:SNPs,haplotype:3'utr,promoter: 826C>T,881A>G (rs2233406,rs3138053) (human)

PMID:19797428 PMID:22022477 PMID:25223483

RGD:40400751 RGD:40902986

NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612

G

NK3 homeobox 1

treatment

mRNA:decreased expression:liver
human gene in a mouse model

NCBI chrNW_004936555:7,087,677...7,091,334
Ensembl chrNW_004936555:7,088,577...7,091,334

G

NLR family CARD domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:757,121...773,924

G

NLR family CARD domain containing 5

protein:increased expression:liver

NCBI chrNW_004936475:9,137,929...9,218,682
Ensembl chrNW_004936475:9,168,391...9,217,251

G

nicotinamide N-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936612:333,421...351,202
Ensembl chrNW_004936612:333,421...351,202

G

nitric oxide synthase 2

treatment

NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051

G

notch receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429

G

nuclear receptor subfamily 0 group B member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,316,857...11,319,669
Ensembl chrNW_004936474:11,316,700...11,319,669

G

nuclear receptor subfamily 1 group H member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936889:223,137...229,968
Ensembl chrNW_004936889:223,101...229,990

G

nuclear receptor subfamily 1 group H member 4

mRNA:splice variant(s):liver (human)
OMIM:114550
intestinally expressed human gene in mouse model
CTD Direct Evidence: marker/mechanism

RGD
MouseDO
CTD

PMID:23213087 PMID:23811326 PMID:24954587 PMID:25496033

RGD:14696796 RGD:14928330 RGD:14928334

NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034

G

NRAS proto-oncogene, GTPase

disease_progression
severity

human gene in mouse model
mRNA, protein:increased expression:liver (mouse, human)

PMID:21993994 PMID:30685691

RGD:14696775 RGD:14696793

NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590

G

neuregulin 1

disease_progression

mRNA:increased expression:liver (human)
associated with hepatitis C;mRNA:altered expression:liver (human

PMID:17393520 PMID:27514687

RGD:39456104 RGD:39456110

NCBI chrNW_004936766:1,104,841...1,306,368
Ensembl chrNW_004936766:1,104,728...1,305,972

G

neuropilin 1

disease_progression

protein:decreased expression:liver

NCBI chrNW_004936574:1,694,433...1,834,720
Ensembl chrNW_004936574:1,694,336...1,834,720

G

NUF2 component of NDC80 kinetochore complex

treatment
disease_progression

CTD Direct Evidence: marker/mechanism

PMID:28284560 PMID:30653265 PMID:31933938

RGD:28867240 RGD:28912742

NCBI chrNW_004936481:21,342,667...21,371,311
Ensembl chrNW_004936481:21,342,786...21,371,328

G

nucleolar and spindle associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:4,705,757...4,732,446
Ensembl chrNW_004936471:4,705,866...4,731,903

G

oncoprotein induced transcript 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936521:6,098,071...6,123,740
Ensembl chrNW_004936521:6,098,111...6,123,745

G

olfactomedin like 2A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:12,999,818...13,031,539
Ensembl chrNW_004936487:12,999,901...13,027,760

G

olfactomedin like 2B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936831:169,866...210,974
Ensembl chrNW_004936831:169,864...211,315

G

origin recognition complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936522:8,580,661...8,610,750
Ensembl chrNW_004936522:8,586,591...8,610,747

G

ornithine transcarbamylase

severity

mRNA:altered expression:liver tumor (human)

NCBI chrNW_004936502:5,234,253...5,291,891
Ensembl chrNW_004936502:5,234,253...5,291,891

G

platelet activating factor acetylhydrolase 1b regulatory subunit 1

disease_progression

mRNA,protein:decreased expression:liver:

NCBI chrNW_004936538:8,612,142...8,693,698
Ensembl chrNW_004936538:8,612,049...8,694,015

G

peptidase domain containing associated with muscle regeneration 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936533:2,684,826...2,764,682
Ensembl chrNW_004936533:2,684,479...2,764,874

G

Parkinsonism associated deglycase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817

G

poly(ADP-ribose) polymerase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642

G

PDZ binding kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936675:704,001...722,769
Ensembl chrNW_004936675:704,516...722,755

G

phosphoenolpyruvate carboxykinase 1

CTD Direct Evidence: marker/mechanism

PMID:19363144 PMID:28284560

NCBI chrNW_004936530:361,872...367,005
Ensembl chrNW_004936530:361,872...367,005

G

PCNA clamp associated factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:24,797,291...24,812,196
Ensembl chrNW_004936471:24,797,393...24,808,227

G

proliferating cell nuclear antigen

treatment

protein:increased expression:liver:

PMID:23219601 PMID:25999787

RGD:10448993 RGD:152177911

NCBI chrNW_004936485:13,766,221...13,771,215

G

programmed cell death 1

disease_progression

associated with hepatitis B;DNA:SNP: : +8669 A>G (human)

PMID:21912640 PMID:27034168

RGD:40818257 RGD:41410800

NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587

G

platelet derived growth factor subunit B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573

G

platelet derived growth factor receptor like

ClinVar Annotator: match by term: Hepatocellular carcinoma

NCBI chrNW_004936614:195,058...241,748
Ensembl chrNW_004936614:195,030...240,502

G

protein disulfide isomerase family A member 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:6,809,181...6,834,189
Ensembl chrNW_004936471:6,809,195...6,836,169

G

pyruvate dehydrogenase kinase 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936585:4,701,012...4,713,421
Ensembl chrNW_004936585:4,700,418...4,714,450

G

phosphoribosylformylglycinamidine synthase

protein:increased activity:hepatoma (rat)
protein:increased expression:liver

NCBI chrNW_004936595:1,483,688...1,499,716
Ensembl chrNW_004936595:1,483,689...1,501,364

G

profilin 2

disease_progression

mRNA:increased expression:liver (human)

G

phosphogluconate dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936623:4,234,869...4,251,690
Ensembl chrNW_004936623:4,234,837...4,252,467

G

phosphoglycerate kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936547:286,267...310,062
Ensembl chrNW_004936547:286,267...310,062

G

prohibitin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:12,127,065...12,138,870
Ensembl chrNW_004936490:12,127,065...12,138,870

G

PHD finger protein 6

exacerbates

mRNA:increased expression:liver (human)

PMID:30888215 PMID:31329335

RGD:155260288 RGD:155260308

NCBI chrNW_004936691:716,723...767,960
Ensembl chrNW_004936691:716,697...768,016

G

pleckstrin homology like domain family A member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936568:4,400,094...4,407,900
Ensembl chrNW_004936568:4,404,818...4,406,006

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

treatment
no_association
severity
susceptibility

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:mutation:exon:
DNA:mutations:exons:
DNA:SNPs: :rs17849071,rs17849079(human)

OMIM
ClinVar
RGD

PMID:15016963 PMID:15520168 PMID:15608678 PMID:16331247 PMID:17376864 More...

RGD:11556371 RGD:14402404 RGD:14402405 RGD:152177911

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

NCBI chrNW_004936540:907,118...1,041,814
Ensembl chrNW_004936540:907,112...1,041,848

G

phosphoinositide-3-kinase regulatory subunit 1

treatment

PMID:25999787 PMID:31801250

RGD:151893509 RGD:152177911

NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537

G

phosphoinositide-3-kinase regulatory subunit 2

treatment

NCBI chrNW_004936596:3,010,526...3,021,848
Ensembl chrNW_004936596:3,010,488...3,021,920

G

phosphoinositide-3-kinase regulatory subunit 3

treatment

NCBI chrNW_004936474:27,095,125...27,171,416
Ensembl chrNW_004936474:27,095,100...27,171,252

G

PIN2 (TERF1) interacting telomerase inhibitor 1

disease_progression

associated with Chronic Hepatitis B; DNA:SNP::rs1469557(human)

NCBI chrNW_004936675:2,641,851...2,706,201
Ensembl chrNW_004936675:2,640,068...2,706,238

G

PITPNM family member 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936677:1,451,974...1,528,864
Ensembl chrNW_004936677:1,430,391...1,529,484

G

paired like homeodomain 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936597:2,211,087...2,217,065
Ensembl chrNW_004936597:2,211,080...2,217,071

G

pyruvate kinase M1/2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:31,589,322...31,617,891
Ensembl chrNW_004936471:31,589,324...31,617,873

G

protein kinase, membrane associated tyrosine/threonine 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:1,191,534...1,196,532
Ensembl chrNW_004936694:1,188,442...1,199,079

G

plakophilin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936567:3,089,902...3,138,252
Ensembl chrNW_004936567:3,089,881...3,138,331

G

placenta associated 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936738:1,484,905...1,503,181
Ensembl chrNW_004936738:1,484,859...1,503,302

G

plasminogen activator, urokinase

OMIM:114550

NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877

G

phospholipase C gamma 1

ameliorates

human cell line in a mouse model

NCBI chrNW_004936561:598,372...631,575
Ensembl chrNW_004936561:598,382...631,581

G

polo like kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936501:8,321,415...8,332,414
Ensembl chrNW_004936501:8,321,305...8,332,424

G

polo like kinase 4

sexual_dimorphism

DNA:hypermethylation:promoter

NCBI chrNW_004936642:2,837,041...2,855,369
Ensembl chrNW_004936642:2,837,022...2,855,103

G

procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

treatment

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936543:1,090,268...1,097,170
Ensembl chrNW_004936543:1,090,253...1,097,301

G

plasmalemma vesicle associated protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:3,511,235...3,523,164
Ensembl chrNW_004936596:3,511,185...3,523,252

G

plexin domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,370,767...14,425,608
Ensembl chrNW_004936490:14,370,795...14,424,209

G

PML nuclear body scaffold

disease_progression
exacerbates
ameliorates

protein:increased expression:liver (human)
associated with hepatitis C
mRNA:increased expression:liver (mouse)

PMID:11511788 PMID:26118777 PMID:31144474

RGD:41404685 RGD:41404687 RGD:41404690

NCBI chrNW_004936471:33,135,186...33,173,218
Ensembl chrNW_004936471:33,135,164...33,177,666

G

PMS1 homolog 2, mismatch repair system component

ClinVar Annotator: match by term: Hepatocellular carcinoma

NCBI chrNW_004936750:439,396...468,747

G

patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase

associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human)

NCBI chrNW_004936718:1,620,034...1,638,315
Ensembl chrNW_004936718:1,619,948...1,638,317

G

polyribonucleotide nucleotidyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:1,989,429...2,032,430
Ensembl chrNW_004936491:1,987,097...2,032,430

G

DNA polymerase gamma, catalytic subunit

susceptibility

DNA:SNPs:introns: (rs1061316, rs758130) (human)

NCBI chrNW_004936483:15,178,947...15,196,277
Ensembl chrNW_004936483:15,179,342...15,195,258

G

paraoxonase 1

disease_progression

mRNA:decreased expression:liver (human)

NCBI chrNW_004936585:4,954,871...4,979,560
Ensembl chrNW_004936585:4,954,869...4,979,591

G

protection of telomeres 1

disease_progression

associated with hepatitis B;DNA:SNP: :rs7784168(human)

NCBI chrNW_004936605:836,824...919,099
Ensembl chrNW_004936605:836,769...920,201

G

peroxisome proliferator activated receptor alpha

susceptibility

associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human)

NCBI chrNW_004936629:3,672,445...3,725,645
Ensembl chrNW_004936629:3,672,460...3,725,626

G

peroxisome proliferator activated receptor gamma

severity

CTD Direct Evidence: therapeutic
protein:decreased expression:liver

PMID:16374840 PMID:27451128

NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743

G

phosphoribosyl pyrophosphate amidotransferase

protein:increased activity:hepatoma (rat)

NCBI chrNW_004936482:18,606,124...18,648,989
Ensembl chrNW_004936482:18,606,124...18,648,681

G

protein phosphatase 1 regulatory inhibitor subunit 1A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:11,765,769...11,775,573
Ensembl chrNW_004936512:11,767,172...11,775,573

G

protein phosphatase 1 regulatory subunit 9A

onset

protein:increased expression:liver (rat)

NCBI chrNW_004936585:4,981,555...5,277,185

G

protein phosphatase 1 regulatory subunit 9B

severity

mRNA, protein:decreased expression:liver (human)

NCBI chrNW_004936490:11,497,389...11,514,191

G

protein regulator of cytokinesis 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:16,034,577...16,061,856
Ensembl chrNW_004936483:16,034,550...16,060,909

G

PR/SET domain 1

disease_progression

associated with hepatitis B;DNA:SNP: :rs1010273(human)

PMID:31100710 PMID:31376415

RGD:150530465 RGD:150530466

NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683

G

peroxiredoxin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:26,641,776...26,653,291
Ensembl chrNW_004936474:26,639,259...26,653,328

G

peroxiredoxin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:1,894,423...1,897,690

G

peroxiredoxin 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936481:14,223,422...14,233,634
Ensembl chrNW_004936481:14,222,696...14,233,641

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

exacerbates

mRNA:increased expression:liver (human)
mRNA:decreased expression:liver (human)
protein:increased expression:liver (human)

PMID:25151370 PMID:28000796 PMID:28205209 PMID:31776854

RGD:151665185 RGD:151665186 RGD:151665188 RGD:151665343

NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346

G

parkin RBR E3 ubiquitin protein ligase

severity

protein:decreased expression:liver (human)

NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872

G

prolactin

onset

protein:increased expression:serum (human)

NCBI chrNW_004936552:7,204,298...7,212,632

G

prominin 1

mRNA:increased expression:liver (mouse)

NCBI chrNW_004936477:11,878,261...12,017,228
Ensembl chrNW_004936477:11,878,012...12,018,177

G

patched 1

disease_progression
severity

PMID:18538319 PMID:22911366

RGD:150523837 RGD:150523842

NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476

G

phosphatase and tensin homolog

exacerbates
severity
treatment

protein:decreased expression:liver (human)
OMIM:114550
CTD Direct Evidence: marker/mechanism
associated with hepatitis B;protein:decreased expression:liver (human)
associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human)

RGD
MouseDO
CTD

PMID:12115563 PMID:12673720 PMID:27022031 PMID:29303510 PMID:30690477 More...

RGD:127285591 RGD:127285603 RGD:127285610 RGD:151893509 RGD:152995524

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

prostaglandin-endoperoxide synthase 2

severity
susceptibility
treatment

protein:increased expression:liver, cytosol
DNA:SNP:promoter:-1195A>G (rs689466) (human)
mRNA,protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:11872629 PMID:12024111 PMID:14563831 PMID:15800977 PMID:16374840 More...

RGD:14695010 RGD:14695011 RGD:14695012 RGD:152177911 RGD:2300283

NCBI chrNW_004936481:3,821,564...3,828,086

G

parathyroid hormone 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:674,088...693,191
Ensembl chrNW_004936596:674,088...693,213

G

protein tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

PMID:14578863 PMID:17203219

NCBI chrNW_004936470:10,379,855...10,578,531
Ensembl chrNW_004936470:10,379,872...10,578,543

G

protein tyrosine phosphatase non-receptor type 13

susceptibility
disease_progression

DNA:SNP: :p.Y2081D(human)

PMID:16489062 PMID:26801674

RGD:152176666 RGD:152599190

NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001

G

protein tyrosine phosphatase receptor type B

disease_progression

mRNA:decreased expression:liver (human)

NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715

G

PYD and CARD domain containing

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805

G

glycogen phosphorylase L

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:14,692,688...14,728,663
Ensembl chrNW_004936495:14,692,332...14,730,231

G

Rac family small GTPase 1

exacerbates

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)
protein:increased expression:liver (human)

PMID:18506888 PMID:20522449 PMID:33482578

RGD:153298967 RGD:153350129

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

Rac GTPase activating protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:7,665,144...7,696,615
Ensembl chrNW_004936512:7,665,208...7,689,112

G

RAD21 cohesin complex component

susceptibility
treatment
exacerbates

associated with hepatitis c, liver cirrhosis;mRNA:increased expression:liver (human)
human cells in a mouse model
protein:increased expression:liver (human)

PMID:28434945 PMID:30698808 PMID:32596342 PMID:33251678

RGD:150520026 RGD:150520029 RGD:150520030 RGD:150520035

NCBI chrNW_004936470:29,377,793...29,403,422
Ensembl chrNW_004936470:29,377,734...29,407,312

G

RAD50 double strand break repair protein

ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:16385572 PMID:18281469 PMID:19409520 PMID:24894818 PMID:25452441 More...

NCBI chrNW_004936647:2,546,100...2,637,524
Ensembl chrNW_004936647:2,543,599...2,637,846

G

RAD52 homolog, DNA repair protein

susceptibility
onset

associated with hepatitis B;DNA:SNP:3'utr: (rs7963551) (human)
mRNA,protein:increased expression:liver (human)

PMID:24729511 PMID:31719794

RGD:151361199 RGD:151361207

NCBI chrNW_004936606:1,070,336...1,099,684
Ensembl chrNW_004936606:1,066,905...1,099,703

G

RAD54 like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:27,276,570...27,316,427
Ensembl chrNW_004936474:27,280,573...27,316,428

G

retinoic acid receptor alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:15,376,217...15,420,638
Ensembl chrNW_004936490:15,376,205...15,421,611

G

RB transcriptional corepressor 1

treatment

CTD Direct Evidence: marker/mechanism

PMID:12029619 PMID:14961299 PMID:33841550

NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846

G

RNA binding motif protein 10

disease_progression

mRNA:decreased expression:liver

NCBI chrNW_004936502:12,923,890...12,952,179
Ensembl chrNW_004936502:12,925,910...12,955,470

G

regulator of calcineurin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:7,942,099...7,950,256
Ensembl chrNW_004936500:7,942,133...7,950,271

G

RecQ like helicase

disease_progression

protein:increased expression:liver

NCBI chrNW_004936548:5,349,878...5,384,603
Ensembl chrNW_004936548:5,362,517...5,384,338

G

ret proto-oncogene

severity

protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma

PMID:7784092 PMID:7845675 PMID:7911697 PMID:8807338 PMID:8918855 More...

NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602

G

regucalcin

protein:decreased expression:liver

NCBI chrNW_004936502:12,872,938...12,891,270
Ensembl chrNW_004936502:12,872,824...12,891,506

G

RPTOR independent companion of MTOR complex 2

severity

mRNA, protein:increased expression:liver (human)

PMID:25371154 PMID:29303510

RGD:152995471 RGD:152995524

NCBI chrNW_004936518:3,198,312...3,314,393
Ensembl chrNW_004936518:3,198,337...3,310,000

G

Ras like without CAAX 1

ameliorates

human cells in mouse model

NCBI chrNW_004936580:5,157,351...5,166,790
Ensembl chrNW_004936580:5,156,565...5,167,040

G

Rho family GTPase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:26,981,358...26,998,902
Ensembl chrNW_004936469:26,981,318...27,000,739

G

ring finger protein 157

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:1,290,515...1,359,262
Ensembl chrNW_004936594:1,290,413...1,359,263

G

ring finger protein 43

exacerbates

human cells in a mouse model

NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828

G

ring finger protein 6

disease_progression

NCBI chrNW_004936948:57,806...67,875
Ensembl chrNW_004936948:55,699...67,972

G

roundabout guidance receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936505:4,329,428...4,711,310
Ensembl chrNW_004936505:4,330,303...4,709,655

G

ribosomal protein S6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936652:1,252,986...1,255,987
Ensembl chrNW_004936652:1,253,025...1,255,906

G

ribosomal protein S6 kinase A3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936624:3,897,878...4,005,664
Ensembl chrNW_004936624:3,897,791...4,000,558

G

ribonucleotide reductase catalytic subunit M1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793

G

ribonucleotide reductase regulatory subunit M2

CTD Direct Evidence: marker/mechanism

PMID:18230555 PMID:28284560

NCBI chrNW_004936532:6,348,041...6,390,144

G

R-spondin 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936639:2,475,710...2,552,725
Ensembl chrNW_004936639:2,475,710...2,552,725

G

rhotekin

mRNA:increased expression:liver

NCBI chrNW_004936556:650,303...665,324
Ensembl chrNW_004936556:650,303...665,324

G

receptor transporter protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:392,885...408,892

G

RUNX family transcription factor 3

CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver

PMID:17094378 PMID:28458013

NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910

G

ryanodine receptor 3

disease_progression

DNA:SNP:3'UTR:rs1044129(human)

NCBI chrNW_004936673:2,078,095...2,434,872
Ensembl chrNW_004936673:1,932,755...2,434,066

G

S100 calcium binding protein A9

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936580:3,228,097...3,230,652
Ensembl chrNW_004936580:3,228,092...3,230,676

G

sarcosine dehydrogenase

severity

mRNA:altered expression:liver tumor (human)

NCBI chrNW_004936669:3,244,302...3,297,906
Ensembl chrNW_004936669:3,243,762...3,297,905

G

salvador family WW domain containing protein 1

OMIM:114550

NCBI chrNW_004936495:14,955,234...14,977,720
Ensembl chrNW_004936495:14,954,542...14,976,580

G

SREBF chaperone

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:1,124,573...1,180,219
Ensembl chrNW_004936596:1,122,042...1,180,297

G

serpin family B member 5

disease_progression

associated with hepatitis B;

NCBI chrNW_004936497:2,067,796...2,089,965
Ensembl chrNW_004936497:2,069,035...2,089,745

G

serpin family F member 1

associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human)

NCBI chrNW_004936538:7,885,816...7,898,308
Ensembl chrNW_004936538:7,885,475...7,899,113

G

SET nuclear proto-oncogene

ClinVar Annotator: match by term: Hepatocellular carcinoma

NCBI chrNW_004936487:16,181,764...16,184,706

G

splicing factor 3b subunit 1

treatment
disease_progression

protein:increased expression:liver
mRNA, protein:increased expression:liver

PMID:29954402 PMID:33038489

RGD:126790493 RGD:126790494

NCBI chrNW_004936506:1,749,591...1,790,860
Ensembl chrNW_004936506:1,749,563...1,791,739

G

splicing factor 3b subunit 4

severity
treatment

mRNA, protein:increased expression:liver(human)
human cells in mouse model
mRNA, protein:increased expression:liver (human)
mRNA, protein:increased expression:liver (rat)

PMID:29059470 PMID:30391496

RGD:155791679 RGD:155804298

NCBI chrNW_004936580:260,013...265,057

G

stratifin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433

G

secreted frizzled related protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936785:1,276,478...1,320,397
Ensembl chrNW_004936785:1,276,420...1,321,017

G

SH3 domain containing GRB2 like 1, endophilin A2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:2,504,372...2,535,993
Ensembl chrNW_004936588:2,504,374...2,536,011

G

SHC adaptor protein 1

protein:increased expression, increased phosphorylation:hepatocyte

NCBI chrNW_004936580:4,511,560...4,522,003
Ensembl chrNW_004936580:4,512,680...4,519,715

G

sonic hedgehog signaling molecule

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599

G

salt inducible kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936612:2,691,729...2,810,975
Ensembl chrNW_004936612:2,691,524...2,810,981

G

SIX homeobox 1

severity

protein:increased expression:liver (human)

NCBI chrNW_004936495:4,839,496...4,842,906
Ensembl chrNW_004936495:4,838,051...4,842,994

G

spindle and kinetochore associated complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:12,777,454...12,793,992
Ensembl chrNW_004936497:12,777,334...12,794,032

G

spindle and kinetochore associated complex subunit 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936720:586,730...610,397
Ensembl chrNW_004936720:586,850...605,406

G

S-phase kinase associated protein 2

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver

PMID:12717389 PMID:19533683

NCBI chrNW_004936518:5,635,856...5,664,057
Ensembl chrNW_004936518:5,637,331...5,664,778

G

solute carrier family 22 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745

G

solute carrier family 25 member 47

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936604:3,976,677...3,981,572
Ensembl chrNW_004936604:3,978,061...3,980,958

G

solute carrier family 26 member 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:425,839...435,590
Ensembl chrNW_004936529:424,720...435,293

G

solute carrier family 2 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713

G

solute carrier family 2 member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947

G

solute carrier family 38 member 1

ameliorates
disease_progression

NCBI chrNW_004936512:4,438,827...4,504,416
Ensembl chrNW_004936512:4,444,684...4,487,165

G

solute carrier family 5 member 5

CTD Direct Evidence: therapeutic

PMID:15347726 PMID:15520214

NCBI chrNW_004936596:3,176,009...3,188,637
Ensembl chrNW_004936596:3,177,422...3,188,637

G

solute carrier family 7 member 5

ameliorates
disease_progression

mRNA:increased expression:liver

PMID:7532544 PMID:23696029 PMID:26389641

RGD:151361140 RGD:151361280 RGD:634202

NCBI chrNW_004936641:1,513,110...1,538,955

G

solute carrier organic anion transporter family member 1B3

exacerbates
disease_progression

mRNA,protein:decreased expression:liver (human)

PMID:21626360 PMID:32534581

RGD:152995417 RGD:152995423

NCBI chrNW_004936548:5,593,908...5,682,187

G

slit guidance ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:8,111,212...8,448,567
Ensembl chrNW_004936477:8,109,228...8,446,653

G

SMAD family member 2

NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697

G

SMAD family member 4

disease_progression

protein:increased expression:liver:
protein:decreased expression:liver

PMID:18971187 PMID:22799322 PMID:23922662 PMID:29924446

RGD:12880056 RGD:18182921 RGD:21066341 RGD:21066342

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

SMAD family member 7

mRNA:increased expression:liver (human)

NCBI chrNW_004936497:13,894,586...13,921,978
Ensembl chrNW_004936497:13,894,580...13,922,065

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

DNA:SNPs: :rs11879293, rs2072382 (human)

NCBI chrNW_004936659:1,152,846...1,246,718
Ensembl chrNW_004936659:1,169,792...1,249,213

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

disease_progression

mRNA:decreased expression:liver

NCBI chrNW_004936619:1,276,239...1,308,945
Ensembl chrNW_004936619:1,275,362...1,308,913

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

ameliorates

mRNA, protein:increased expression:liver (human)

NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038

G

structural maintenance of chromosomes 3

exacerbates

mRNA:increased editing:cds:p.K96R,p.Q103R(human)

NCBI chrNW_004936486:1,409,757...1,436,206
Ensembl chrNW_004936486:1,408,045...1,435,875

G

SMG9 nonsense mediated mRNA decay factor

severity

NCBI chrNW_004936706:908,471...929,075
Ensembl chrNW_004936706:908,867...929,305

G

smoothened, frizzled class receptor

disease_progression

DNA:SNP: :rs3824 (human)

NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281

G

snail family transcriptional repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987

G

small nuclear ribonucleoprotein polypeptide E

human gene in a mouse model

NCBI chrNW_004936567:849,300...855,214
Ensembl chrNW_004936567:849,397...855,187

G

SNW domain containing 1

severity

protein:increased expression:liver (human)

NCBI chrNW_004936488:6,494,556...6,531,297
Ensembl chrNW_004936488:6,494,562...6,531,600

G

sorting nexin 27

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:1,815,582...1,893,076
Ensembl chrNW_004936580:1,815,651...1,893,753

G

sterol O-acyltransferase 1

exacerbates

associated with hepatitis B;protein:increased expression:liver (human)

NCBI chrNW_004936481:9,614,605...9,669,705
Ensembl chrNW_004936481:9,616,850...9,669,705

G

sterol O-acyltransferase 2

NCBI chrNW_004936512:10,420,847...10,430,813
Ensembl chrNW_004936512:10,420,804...10,430,881

G

suppressor of cytokine signaling 1

treatment

associated with liver cirrhosis;DNA:altered methylation:liver:
DNA:hypermethylation:CpG island, 5'untranslated region:

PMID:14614012 PMID:15235874 PMID:18843197 PMID:22318090

RGD:150573687 RGD:150573689 RGD:150573700 RGD:150573703

NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165

G

suppressor of cytokine signaling 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936507:10,013,982...10,015,480
Ensembl chrNW_004936507:10,012,101...10,014,456

G

suppressor of cytokine signaling 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451

G

superoxide dismutase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:10,345,154...10,352,873
Ensembl chrNW_004936500:10,345,154...10,352,867

G

superoxide dismutase 2

disease_progression
susceptibility

CTD Direct Evidence: marker/mechanism
protein:increased expression:saliva
associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human)

PMID:15869407 PMID:16767786 PMID:18760346 PMID:19731237 PMID:21472284 More...

RGD:1581242 RGD:26923907 RGD:26923955 RGD:27095881

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

SRY-box transcription factor 30

disease_progression
exacerbates

NCBI chrNW_004936515:5,501,315...5,537,946
Ensembl chrNW_004936515:5,458,393...5,537,946

G

sperm associated antigen 9

associated with Human Viral Hepatitis

NCBI chrNW_004936490:10,663,155...10,796,658
Ensembl chrNW_004936490:10,663,122...10,799,474

G

SPC25 component of NDC80 kinetochore complex

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:10,628,235...10,652,168
Ensembl chrNW_004936469:10,628,230...10,652,232

G

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1

ameliorates

human cells in mouse model

NCBI chrNW_004936597:4,000,433...4,493,920
Ensembl chrNW_004936597:4,000,400...4,156,221

G

speckle type BTB/POZ protein

exacerbates

human cells in mouse model
mRNA:decreased expression:liver (human)

PMID:26156804 PMID:33209975

RGD:11074965 RGD:153298924

NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155

G

secreted phosphoprotein 1

disease_progression

mRNA:increased expression:liver (human)

PMID:16047475 PMID:35693827

RGD:153344586 RGD:1581375

NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079

G

SprT-like N-terminal domain

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936484:19,391,685...19,402,938
Ensembl chrNW_004936484:19,391,420...19,402,944

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483

G

sterol regulatory element binding transcription factor 1

CTD Direct Evidence: marker/mechanism

PMID:14563831 PMID:21147110

NCBI chrNW_004936741:1,408,669...1,419,717
Ensembl chrNW_004936741:1,406,521...1,419,776

G

sterol regulatory element binding transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:115,923...174,614
Ensembl chrNW_004936492:115,821...174,775

G

serum response factor

NCBI chrNW_004936476:16,779,941...16,789,499
Ensembl chrNW_004936476:16,782,233...16,789,130

G

sushi repeat containing protein X-linked

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936502:5,010,692...5,107,221
Ensembl chrNW_004936502:5,010,682...5,107,254

G

serine and arginine rich splicing factor 1

mRNA:increased expression:liver (human)

NCBI chrNW_004936490:5,055,258...5,059,118
Ensembl chrNW_004936490:5,055,253...5,059,116

G

serine and arginine rich splicing factor 2

disease_progression
treatment

PMID:28082404 PMID:29278882 PMID:32372053

RGD:150429663 RGD:150429666 RGD:150429692

NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

protein:increased activity:liver:

NCBI chrNW_004936578:2,966,690...3,107,237
Ensembl chrNW_004936578:2,966,694...3,003,970

G

stabilin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:10,678,074...10,817,870
Ensembl chrNW_004936492:10,678,115...10,833,963

G

signal transducer and activator of transcription 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756

G

signal transducer and activator of transcription 3

protein:increased phosphorylation:liver (mouse)

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

G

signal transducer and activator of transcription 4

susceptibility

CTD Direct Evidence: marker/mechanism
Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human)

PMID:23242368 PMID:26745093

NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689

G

stanniocalcin 2

disease_progression

mRNA:increased expression:liver (human)

NCBI chrNW_004936609:2,319,546...2,331,049
Ensembl chrNW_004936609:2,319,111...2,332,988

G

stromal interaction molecule 1

mRNA:increased expression:liver (human)

NCBI chrNW_004936498:849,775...1,063,552
Ensembl chrNW_004936498:849,739...1,063,552

G

stathmin 1

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:28284560 PMID:28982915

NCBI chrNW_004936474:10,470,006...10,475,557
Ensembl chrNW_004936474:10,468,728...10,475,594

G

transforming acidic coiled-coil containing protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:21,648,958...21,665,855
Ensembl chrNW_004936477:21,648,716...21,665,625

G

transgelin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936740:689,745...697,145
Ensembl chrNW_004936740:689,595...699,763

G

transaldolase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936888:531,002...540,194
Ensembl chrNW_004936888:531,020...540,820

G

TatD DNase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:23,123,693...23,156,764
Ensembl chrNW_004936470:23,123,730...23,167,274

G

T-box transcription factor 3

severity
disease_progression
ameliorates

protein:increased expression:liver (human)
human cells in mouse model

PMID:22811581 PMID:26922018 PMID:29295731 PMID:30578408 PMID:33577921

RGD:151361112 RGD:151361114 RGD:151361122 RGD:151361123 RGD:151361132

NCBI chrNW_004936558:7,230,361...7,243,651
Ensembl chrNW_004936558:7,230,668...7,244,361

G

transcription factor 19

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936837:821,884...825,766
Ensembl chrNW_004936837:821,861...826,088

G

transcriptional and immune response regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936843:485,453...486,895
Ensembl chrNW_004936843:486,387...486,707

G

tubulin epsilon and delta complex 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:1,591,392...1,595,693
Ensembl chrNW_004936694:1,590,919...1,595,719

G

TEK receptor tyrosine kinase

protein:increased expression

NCBI chrNW_004936611:2,420,176...2,531,726
Ensembl chrNW_004936611:2,420,172...2,531,722

G

telomerase associated protein 1

disease_progression
susceptibility

associated with hepatitis B;DNA:SNPs: :rs1713449,rs1760898, rs872072 (human)
DNA:SNP:intron:rs1760893(human)

PMID:23907815 PMID:27305982

RGD:152975963 RGD:152977750

NCBI chrNW_004936877:575,264...613,965
Ensembl chrNW_004936877:575,037...641,642

G

telomerase reverse transcriptase

susceptibility
disease_progression
no_association
treatment

DNA:SNPs::rs2736098(human)
ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with hepatitis B;DNA:SNP: :rs13167280 (human)
DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human)
DNA:mutations:promoter:
DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human

PMID:17175353 PMID:19184104 PMID:23000435 PMID:23907815 PMID:25123086 More...

RGD:11564803 RGD:14696767 RGD:14696768 RGD:14696769 RGD:14696770 RGD:150530496 RGD:152975963

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

tet methylcytosine dioxygenase 2

severity
disease_progression
ameliorates

mRNA:decreased expression:liver (human)
mRNA, protein:decreased expression:liver (human)
mRNA, protein:increased expression:liver (human)
human cells in mouse model

PMID:26366235 PMID:29331390 PMID:30070373 PMID:33097695

RGD:150429595 RGD:150429597 RGD:150429684 RGD:150429689

NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615

G

tissue factor pathway inhibitor 2

CTD Direct Evidence: marker/mechanism

PMID:17464989 PMID:28284560

NCBI chrNW_004936803:69,296...90,270
Ensembl chrNW_004936803:73,946...90,295

G

transferrin receptor

mRNA:increased expression:liver

NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543

G

transforming growth factor alpha

associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism

PMID:9029167 PMID:9060843 PMID:15565109

NCBI chrNW_004936491:14,659,089...14,758,614
Ensembl chrNW_004936491:14,657,100...14,758,848

G

transforming growth factor beta 1

mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism

PMID:9029167 PMID:28100771

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

transforming growth factor beta 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007

G

transforming growth factor beta receptor 2

mRNA, protein:decreased expression:liver

NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430

G

transglutaminase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936485:16,259,197...16,325,167
Ensembl chrNW_004936485:16,259,643...16,296,783

G

tyrosine hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936794:478,651...486,887
Ensembl chrNW_004936794:478,614...487,061

G

thioesterase superfamily member 4

CTD Direct Evidence: therapeutic

NCBI chrNW_004936580:2,058,960...2,085,919
Ensembl chrNW_004936580:2,058,643...2,085,945

G

Thy-1 cell surface antigen

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:4,323,905...4,329,940
Ensembl chrNW_004936542:4,323,408...4,330,077

G

TOPBP1 interacting checkpoint and replication regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:15,381,486...15,422,600

G

T cell immunoglobulin and mucin domain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936515:6,106,991...6,141,027

G

thymidine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:2,784,891...2,794,693
Ensembl chrNW_004936594:2,784,226...2,794,830

G

toll like receptor 2

susceptibility

DNA:deletion:promoter:-196 to -174(human)
associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human)

PMID:21500195 PMID:22859216 PMID:27183918

RGD:15090813 RGD:15090815 RGD:18337266

NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788

G

toll like receptor 3

disease_progression

NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907

G

toll like receptor 4

susceptibility

DNA:SNP: :rs1057317(human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:
DNA:SNPs, haplotype: :multiples

PMID:21559380 PMID:25179842 PMID:27022031 PMID:28578348

RGD:14700552 RGD:14700557 RGD:14700558

NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095

G

toll like receptor 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:2,593,544...2,610,972
Ensembl chrNW_004936470:2,607,508...2,610,675

G

transmembrane protein 70

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936648:2,636,667...2,650,311

G

tumor necrosis factor

disease_progression

mRNA, protein:increased expression:liver, blood serum (mouse)
CTD Direct Evidence: marker/mechanism

PMID:26569409 PMID:26890368 PMID:27022031

RGD:11344640 RGD:14975171

NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766

G

TNF alpha induced protein 3

ameliorates
sexual_dimorphism

protein:decreased expression:liver (human)
mRNA,protein:increased expression:liver (human)
mRNA:decreased expression:liver (human)

PMID:26538215 PMID:27253414 PMID:29190981 PMID:32015333

RGD:151347600 RGD:151347604 RGD:151347618 RGD:151347622

NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

NCBI chrNW_004936593:212,642...230,645
Ensembl chrNW_004936593:212,532...230,651

G

TNF superfamily member 9

NCBI chrNW_004936588:3,844,924...3,847,218

G

TRAF2 and NCK interacting kinase

disease_progression

protein:increased phosphorylation:liver, nucleus (human)

NCBI chrNW_004936593:1,166,995...1,546,253
Ensembl chrNW_004936593:1,167,395...1,540,399

G

tonsoku like, DNA repair protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:7,817,444...7,829,124

G

DNA topoisomerase II alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978

G

tumor protein p53

treatment

ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA

ClinVar
OMIM
RGD

PMID:253702 PMID:960674 PMID:1349102 PMID:1349175 PMID:1359493 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor protein p73

exacerbates
treatment

mRNA:increased expression:liver (human)
protein:decreased phosphorylation:liver (human)
human cells in a mouse model

PMID:14760085 PMID:19664633 PMID:25371988 PMID:27359056 PMID:31429776

RGD:151347579 RGD:151347592 RGD:151347593 RGD:151347594 RGD:151347596

NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464

G

TPX2 microtubule nucleation factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936485:18,718,801...18,773,315
Ensembl chrNW_004936485:18,718,795...18,767,951

G

TNF receptor associated factor 7

treatment

mRNA:increased expression:liver

NCBI chrNW_004936694:1,868,309...1,886,772

G

TRAF interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:1,434,629...1,466,382

G

tripartite motif containing 24

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936592:2,902,805...2,962,602
Ensembl chrNW_004936592:2,863,743...2,963,977

G

thyroid hormone receptor interactor 13

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936815:734,029...745,381
Ensembl chrNW_004936815:734,167...745,092

G

trophinin associated protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:7,079,485...7,086,382

G

TSC complex subunit 2

severity

protein:decreased expression:liver (human)

NCBI chrNW_004936694:1,958,152...1,993,373
Ensembl chrNW_004936694:1,958,154...1,993,363

G

thymic stromal lymphopoietin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:5,495,872...5,500,462

G

thiosulfate sulfurtransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:3,880,545...3,886,881
Ensembl chrNW_004936492:3,880,500...3,886,950

G

tetratricopeptide repeat domain 36

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:3,567,469...3,571,393
Ensembl chrNW_004936542:3,566,876...3,571,504

G

TTK protein kinase

disease_progression

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)

PMID:28284560 PMID:35693827

NCBI chrNW_004936510:10,176,968...10,213,483

G

transthyretin

disease_progression

protein:increased expression:blood serum (rat)
protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (human)

PMID:16240287 PMID:28876464 PMID:29534342

RGD:151356736 RGD:151664602 RGD:151665161

NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566

G

thioredoxin interacting protein

OMIM:114550

NCBI chrNW_004936867:722,544...726,595
Ensembl chrNW_004936867:722,514...726,617

G

thymidylate synthetase

susceptibility

CTD Direct Evidence: marker/mechanism
DNA:deletion:3'UTR:1494del6(human)

PMID:17659576 PMID:18019677 PMID:18230555

NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840

G

uveal autoantigen with coiled-coil domains and ankyrin repeats

OMIM:114550

NCBI chrNW_004936471:30,213,742...30,312,873
Ensembl chrNW_004936471:30,211,588...30,363,992

G

ubiquitin D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936723:1,218,621...1,221,070
Ensembl chrNW_004936723:1,218,258...1,221,451

G

ubiquitin conjugating enzyme E2 C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936514:7,204,332...7,208,340
Ensembl chrNW_004936514:7,199,539...7,207,655

G

ubiquitin conjugating enzyme E2 E2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:14,988,802...15,280,650

G

ubiquitin conjugating enzyme E2 T

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936567:2,222,317...2,226,725
Ensembl chrNW_004936567:2,222,317...2,226,678

G

ubiquitin protein ligase E3 component n-recognin 5

treatment

NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134

G

ubiquitin C-terminal hydrolase L1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936482:8,551,749...8,563,586
Ensembl chrNW_004936482:8,551,603...8,563,651

G

ubiquitin like with PHD and ring finger domains 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:2,863,651...2,890,116
Ensembl chrNW_004936588:2,862,367...2,888,946

G

uridine monophosphate synthetase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936725:553,278...564,846
Ensembl chrNW_004936725:549,804...565,141

G

ubiquitin specific peptidase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:4,284,243...4,310,545
Ensembl chrNW_004936542:4,285,819...4,307,925

G

ubiquitin specific peptidase 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:941,042...989,781
Ensembl chrNW_004936529:938,501...989,884

G

vasorin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:128,398...138,954
Ensembl chrNW_004936694:128,273...138,954

G

vav guanine nucleotide exchange factor 1

mRNA:decreased expression:liver

NCBI chrNW_004936588:4,058,312...4,107,330
Ensembl chrNW_004936588:4,058,343...4,107,109

G

vascular cell adhesion molecule 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936748:785,491...802,791
Ensembl chrNW_004936748:785,455...803,048

G

vitamin D receptor

susceptibility

associated with alcoholic liver cirrhosis;DNA:haplotype::
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human)

PMID:20572305 PMID:24033266 PMID:25541958 PMID:25741868 PMID:28492532

RGD:14402025 RGD:14402026

NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109

G

vascular endothelial growth factor A

susceptibility
treatment
disease_progression

DNA:SNP: :2578C>A (human)
associated with liver cirrhosis; protein:increased expression:platelet, liver:
protein:increased expression:serum:
DNA:polymorphism:promoter:-2578C>A (rs699947)(human)
protein:increased expression:liver

PMID:16835748 PMID:18392108 PMID:18544126 PMID:24445728 PMID:25999787 More...

RGD:11527070 RGD:126848814 RGD:15003194 RGD:15003196 RGD:15003200 RGD:15014783 RGD:15036790 RGD:152177911

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

vascular endothelial growth factor C

associated with liver cirrhosis; protein:increased expression:liver:

NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559

G

von Hippel-Lindau tumor suppressor

disease_progression

NCBI chrNW_004936602:3,135,790...3,140,622

G

vasoactive intestinal peptide receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936695:2,564,917...2,597,009
Ensembl chrNW_004936695:2,564,890...2,607,676

G

V-set and immunoglobulin domain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936635:2,167,633...2,191,725
Ensembl chrNW_004936635:2,167,617...2,191,740

G

WD repeat domain 62

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936922:80,136...119,702
Ensembl chrNW_004936922:80,217...119,653

G

WD repeat domain 76

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:6,878,350...6,923,951
Ensembl chrNW_004936471:6,878,584...6,923,921

G

Wnt family member 2

susceptibility

associated with hepatitis B;DNA:SNP: :rs4730775(human)

NCBI chrNW_004936589:1,825,209...1,866,898
Ensembl chrNW_004936589:1,825,209...1,866,889

G

WD repeat containing antisense to TP53

RNA:increased expression:liver:

NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791

G

xanthine dehydrogenase

protein:decreased activity:tumor (rat)

NCBI chrNW_004936493:1,762,814...1,824,501
Ensembl chrNW_004936493:1,762,869...1,823,238

G

exportin 1

treatment
ameliorates
exacerbates

human cell line in a mouse model
mRNA:increased expression:liver (human)

PMID:25030088 PMID:27013579 PMID:31371628

RGD:151665796 RGD:151667433 RGD:151667441

NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343

G

exportin 5

severity

DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human)

NCBI chrNW_004936476:16,434,629...16,481,044
Ensembl chrNW_004936476:16,434,638...16,481,044

G

X-ray repair cross complementing 1

disease_progression
susceptibility
severity
no_association

DNA:SNPs:cds: 194C>T, 280A>G (human)
DNA:SNPs:exon 9, exon 15: c.910A>G, c.1686C>G (human)
DNA:missense mutation:cds:p.R399Q (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)
DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human)
DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human)
DNA:missense mutation:cds:p.R399Q (rs25487) (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human)
DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human)
DNA:SNPs:exons:c.1254C>T, c.1517G>C (human)
associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human)
DNA:missense mutation:cds:c.1804C>A (p.G506A) (human)
associated with Chronic Hepatitis C;DNA:SNP:exon 14: c.1517G>C, p.506G>A (human)
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human)
DNA:SNP:exon 13: c.1471G>A, p.E491K (human)

PMID:14519756 PMID:19194663 PMID:22502666 PMID:23454624 PMID:23493666 More...

RGD:14696702 RGD:14696772 RGD:14696773 RGD:14985238 RGD:14985240 RGD:14985242 RGD:14985243 RGD:15014789 RGD:15014790 RGD:15014791 RGD:15014792 RGD:15036794 RGD:15036797 RGD:150530503 RGD:150530624 RGD:150540332 RGD:150540333

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

Yes1 associated transcriptional regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936551:5,638,383...5,740,523
Ensembl chrNW_004936551:5,634,751...5,740,567

G

YTH N6-methyladenosine RNA binding protein F2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:12,791,121...12,827,122
Ensembl chrNW_004936474:12,791,073...12,827,122

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

severity

NCBI chrNW_004936470:42,444,671...42,470,548
Ensembl chrNW_004936470:42,445,412...42,470,900

G

zinc finger CCCH-type containing 12D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:2,454,889...2,472,392
Ensembl chrNW_004936489:2,455,728...2,472,328

G

zinc finger homeobox 3

severity
disease_progression

human cell line in a mouse model
associated with Chronic Hepatitis B;protein:decreased expression:blood serum (human)

PMID:20534899 PMID:32277050

RGD:151361162 RGD:151361169

NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544

G

ZFP36 ring finger protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936661:2,251,148...2,253,527
Ensembl chrNW_004936661:2,250,665...2,253,787

G

Zic family member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:10,599,717...10,605,187
Ensembl chrNW_004936472:10,602,102...10,605,191

G

Zic family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936519:8,007,605...8,025,831
Ensembl chrNW_004936519:8,004,926...8,025,831

G

Zic family member 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:10,615,843...10,623,221
Ensembl chrNW_004936472:10,616,122...10,622,338

G

zinc finger protein 23

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:22,283,924...22,293,074
Ensembl chrNW_004936475:22,272,514...22,293,278

G

ZW10 interacting kinetochore protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936693:1,539,987...1,551,685

hepatocellular clear cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

isocitrate dehydrogenase (NADP(+)) 1

disease_progression

DNA:polymorphism: :rs12478635(human)
DNA:misssense mutation:cds:p.Arg132Cys(human)

PMID:25355558 PMID:28403884

RGD:14974227 RGD:14974228

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

G

isocitrate dehydrogenase (NADP(+)) 2

disease_progression

DNA:polymorphism: :rs11632348(human)

NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341

G

leptin

mRNA:increased expression:liver:

NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334

G

leptin receptor

mRNA:increased expression:liver

NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444

G

telomerase reverse transcriptase

disease_progression

mRNA:increased expression:liver:

PMID:20723213 PMID:28460432

RGD:14696783 RGD:14696785

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

Hereditary Adrenocortical Carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

lysosomal trafficking regulator

ClinVar Annotator: match by term: Adrenocortical carcinoma, hereditary

NCBI chrNW_004936484:16,750,976...16,915,999
Ensembl chrNW_004936484:16,763,511...16,916,022

G

tumor protein p53

ClinVar Annotator: match by term: Adrenocortical carcinoma, hereditary

PMID:224644 PMID:253702 PMID:1200021 PMID:1349175 PMID:1394133 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

hereditary renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

deoxyribonuclease 1

ClinVar Annotator: match by term: Hereditary renal cell carcinoma

NCBI chrNW_004936694:704,948...715,846
Ensembl chrNW_004936694:704,692...710,501

G

epidermal growth factor

ClinVar Annotator: match by term: Hereditary renal cell carcinoma

NCBI chrNW_004936563:1,058,803...1,181,393

G

poly(ADP-ribose) polymerase 1

ClinVar Annotator: match by term: Hereditary renal cell carcinoma

NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642

G

succinate dehydrogenase complex flavoprotein subunit A

ClinVar Annotator: match by term: Hereditary renal cell carcinoma

PMID:25741868 PMID:26467025 PMID:28492532 PMID:28546994 PMID:30680959 More...

NCBI chrNW_004936815:1,148,963...1,167,585
Ensembl chrNW_004936815:1,148,963...1,167,568

G

TNF receptor associated protein 1

ClinVar Annotator: match by term: Hereditary renal cell carcinoma

NCBI chrNW_004936694:667,687...704,994
Ensembl chrNW_004936694:667,691...704,994

Intestinal Carcinoid Tumors

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nucleosome assembly protein 1 like 1

mRNA:increased expression:intestinal mucosa (human)

NCBI chrNW_004936568:4,416,225...4,440,566
Ensembl chrNW_004936568:4,419,652...4,440,608

G

succinate dehydrogenase complex subunit D

ClinVar Annotator: match by term: Carcinoid tumors, intestinal

PMID:12007193 PMID:12111639 PMID:12386824 PMID:12696072 PMID:14557476 More...

NCBI chrNW_004936612:2,357,336...2,369,204

intrahepatic cholangiocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Intrahepatic cholangiocarcinoma

PMID:24728327 PMID:25479140 PMID:25741868 PMID:26467025 PMID:26530882 More...

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

AT-rich interaction domain 1A

disease_progression
exacerbates

mRNA,protein:decreased expression:intrahepatic bile duct (human)

PMID:27433094 PMID:30849962 PMID:31665232

RGD:126775257 RGD:126781775 RGD:14974231

NCBI chrNW_004936474:11,148,857...11,197,312

G

BRCA1 associated deubiquitinase 1

disease_progression

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

beclin 1

disease_progression

NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151

G

B-Raf proto-oncogene, serine/threonine kinase

severity

DNA:missense mutation:cds:p.V600E (human)

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

Fas cell surface death receptor

disease_progression

NCBI chrNW_004936735:209,369...234,582

G

Fas ligand

severity

NCBI chrNW_004936481:14,789,547...14,795,780

G

forkhead box P3

DNA:hypomethylation:liver

NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308

G

heat shock protein 90 alpha family class A member 1

disease_progression

protein:increased expression:liver (human)

NCBI chrNW_004936835:316,767...321,999
Ensembl chrNW_004936835:316,767...321,990

G

heat shock protein 90 alpha family class B member 1

disease_progression

protein:increased expression:liver (human)

NCBI chrNW_004936476:15,830,459...15,836,994
Ensembl chrNW_004936476:15,830,459...15,835,535

G

isocitrate dehydrogenase (NADP(+)) 1

no_association

DNA:misssense mutations:cds:p.Arg132Cys,Arg132Leu (human)

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

G

isocitrate dehydrogenase (NADP(+)) 2

disease_progression

mRNA:decreased expression:liver (mouse)
DNA:mutations: :

PMID:22824796 PMID:32463951

RGD:149735894 RGD:14985256

NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341

G

lysine demethylase 5C

exacerbates

protein:decreased expression:bile duct (human)

NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966

G

KRAS proto-oncogene, GTPase

disease_progression

DNA:mutations::

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

lipocalin 2

treatment

Protein:increased expression:bile duct

NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221

G

membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

disease_progression

protein:increased expression:intrahepatic bile duct (human)

NCBI chrNW_004936637:985,706...1,154,670
Ensembl chrNW_004936637:560,298...1,151,850

G

LDL receptor related protein 1B

exacerbates

DNA:mutations:multiple: (human)

NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283

G

polybromo 1

disease_progression

protein:increased expression:intrahepatic bile duct (human)

PMID:27864835 PMID:30377796

RGD:150340628 RGD:152998946

NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052

G

phosphatase and tensin homolog

disease_progression

protein:decreased expression:liver (human)

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

ring finger protein 43

exacerbates

mRNA, protein:decreased expression:liver, bile duct epithelium (human)

NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828

G

SMAD family member 4

disease_progression

mRNA,protein:decreased expression:intrahepatic bile duct

PMID:16917866 PMID:23981608

RGD:18936999 RGD:21066336

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

telomerase associated protein 1

mRNA:increased expression:hepatocyte,biliary epithelium.

NCBI chrNW_004936877:575,264...613,965
Ensembl chrNW_004936877:575,037...641,642

invasive ductal carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1

disease_progression

NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427

G

ATP binding cassette subfamily C member 9

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936548:4,983,461...5,110,693
Ensembl chrNW_004936548:4,987,847...5,108,104

G

ADAM metallopeptidase domain 28

disease_progression

DNA:hypermethylation:CpG island

NCBI chrNW_004936555:7,615,639...7,660,776
Ensembl chrNW_004936555:7,617,822...7,664,215

G

advanced glycosylation end-product specific receptor

protein:increased expression:breast

NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147

G

AKT serine/threonine kinase 1

DNA:missense mutation:p.E17K (human)

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

arachidonate 5-lipoxygenase

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

autocrine motility factor receptor

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936475:8,692,969...8,727,252
Ensembl chrNW_004936475:8,692,844...8,727,385

G

annexin A1

treatment

PMID:18776816 PMID:19171478

RGD:7421535 RGD:7421560

NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413

G

annexin A2

treatment

NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503

G

androgen receptor

severity

NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932

G

amphiregulin

NCBI chrNW_004936598:1,276,599...1,283,612
Ensembl chrNW_004936598:1,274,565...1,283,746

G

actin related protein 2/3 complex subunit 2

protein:increased expression:breast (human)

NCBI chrNW_004936569:758,358...786,995
Ensembl chrNW_004936569:758,199...786,760

G

activating transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:2,114,478...2,115,969
Ensembl chrNW_004936492:2,110,634...2,115,996

G

aurora kinase A

protein:altered expression

NCBI chrNW_004936875:295,238...310,457

G

BAG cochaperone 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936524:1,793,001...1,804,145
Ensembl chrNW_004936524:1,791,119...1,804,151

G

BRCA1 DNA repair associated

ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast

PMID:7493024 PMID:9063749 PMID:10196379 PMID:11179017 PMID:11400546 More...

NCBI chrNW_004936490:17,735,444...17,801,456

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast | ClinVar Annotator: match by term: Invasive Ductal Carcinoma, Not Otherwise Specified

PMID:11062481 PMID:11927503 PMID:14555511 PMID:14973102 PMID:15145354 More...

NCBI chrNW_004936472:26,945,659...27,017,693

G

BRMS1 transcriptional repressor and anoikis regulator

disease_progression

mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors

NCBI chrNW_004936599:3,259,868...3,267,172
Ensembl chrNW_004936599:3,259,835...3,267,676

G

calcium voltage-gated channel subunit alpha1 C

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936606:2,168,104...2,867,560
Ensembl chrNW_004936606:2,168,625...2,865,758

G

calcium voltage-gated channel subunit alpha1 H

ClinVar Annotator: match by term: Breast cancer, invasive ductal

PMID:26467025 PMID:27148582 PMID:28492532

NCBI chrNW_004936694:2,702,224...2,724,574

G

caveolin 1

no_association

DNA:missense mutation: :p.P132L (human)

NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170

G

coiled-coil domain containing 180

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936524:6,168,334...6,230,934
Ensembl chrNW_004936524:6,168,938...6,230,925

G

coiled-coil domain containing 71 like

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004939850:3,101...4,265
Ensembl chrNW_004939850:3,547...4,283

G

C-C motif chemokine ligand 5

protein:increased expression:breast, ductal carcinoma (human)

NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965

G

cyclin D3

severity

protein:increased expression:breast

NCBI chrNW_004936476:17,799,754...17,886,835
Ensembl chrNW_004936476:17,879,869...17,886,827

G

CD274 molecule

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602

G

CD44 molecule (IN blood group)

disease_progression

protein:increased expression:breast

NCBI chrNW_004936533:2,949,026...3,033,166

G

cadherin 1

CTD Direct Evidence: marker/mechanism

PMID:8557030 PMID:17660459

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

claudin 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:2,984,797...2,986,563
Ensembl chrNW_004936543:2,984,996...2,985,625

G

clusterin

NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836

G

cyclin and CBS domain divalent metal cation transport mediator 1

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936636:646,309...699,768
Ensembl chrNW_004936636:644,876...699,824

G

coronin 6

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936538:5,724,336...5,732,487
Ensembl chrNW_004936538:5,723,994...5,732,525

G

C3 and PZP like alpha-2-macroglobulin domain containing 8

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936596:3,756,446...3,819,840

G

carboxypeptidase X, M14 family member 2

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936486:12,250,128...12,335,578
Ensembl chrNW_004936486:12,251,199...12,345,542

G

cAMP responsive element binding protein 3

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936524:3,727,104...3,730,962
Ensembl chrNW_004936524:3,727,098...3,730,975

G

CRK like proto-oncogene, adaptor protein

disease_progression

protein:increased expression:breast

NCBI chrNW_004936619:2,447,686...2,479,589
Ensembl chrNW_004936619:2,447,614...2,479,805

G

discs large MAGUK scaffold protein 1

DNA:mutation:CDS:multiple nonsynonymous mutations

NCBI chrNW_004936833:551,989...843,064
Ensembl chrNW_004936833:551,799...844,121

G

estrogen receptor binding site associated antigen 9

mRNA, protein:increased expression:breast

NCBI chrNW_004936470:35,449,920...35,473,635
Ensembl chrNW_004936470:35,450,292...35,473,110

G

erb-b2 receptor tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939

G

FYVE, RhoGEF and PH domain containing 1

protein:increased expression:breast (human)

NCBI chrNW_004936751:1,355,606...1,397,282
Ensembl chrNW_004936751:1,351,795...1,397,288

G

fragile histidine triad diadenosine triphosphatase

DNA:loss of heterozygosity,hypermethylation:breast:LOH in 8/40 tumors (20%), hypermethylation in 22/46 tumors (48%), significant positive association found (p=0.04)

NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506

G

far upstream element binding protein 1

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942

G

hypoxia inducible factor 1 subunit alpha

protein:altered localization:nucleus

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

homeobox B7

mRNA:increased expression:breast epithelium (human)

NCBI chrNW_004936490:12,777,005...12,780,515
Ensembl chrNW_004936490:12,777,020...12,780,522

G

hydroxysteroid 17-beta dehydrogenase 1

severity

protein:decreased expression:ductal breast carcinoma (human)

NCBI chrNW_004936490:17,312,390...17,314,423
Ensembl chrNW_004936490:17,312,390...17,314,409

G

HtrA serine peptidase 2

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936556:741,718...746,016
Ensembl chrNW_004936556:741,718...749,090

G

interleukin 13

protein:increased expression:breast

NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373

G

interleukin 18

protein:increased expression:breast

NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189

G

inhibin subunit alpha

protein:decreased expression:tumor:significantly lower in invasive, infiltrating and metastatic tumors than in ductal carcinoma in situ tumors

NCBI chrNW_004936569:1,949,747...1,954,179
Ensembl chrNW_004936569:1,950,297...1,954,165

G

junction plakoglobin

disease_progression

protein:decreased expression:tumor:associated with higher Robinson grade (p=0.016) and lymph node metastases (p=0.012)

NCBI chrNW_004936490:16,671,176...16,694,552
Ensembl chrNW_004936490:16,668,575...16,694,615

G

KiSS-1 metastasis suppressor

disease_progression

mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors

NCBI chrNW_004936567:584,443...595,045
Ensembl chrNW_004936567:584,443...586,837

G

KIT proto-oncogene, receptor tyrosine kinase

severity

protein:decreased expression:tumor:loss of expression associated with lymph node metastasis (p<0.0001) and reduced disease-free survival (p=0.0041)

NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274

G

kinase non-catalytic C-lobe domain containing 1

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936486:19,287,468...19,341,127
Ensembl chrNW_004936486:19,287,462...19,341,145

G

adhesion G protein-coupled receptor B1

disease_progression

NCBI chrNW_004936470:9,247,749...9,313,230
Ensembl chrNW_004936470:9,248,319...9,313,230

G

keratin-associated protein 10-12

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936778:1,582,160...1,583,314

G

lecithin retinol acyltransferase

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936576:1,491,480...1,498,568
Ensembl chrNW_004936576:1,492,297...1,501,917

G

mitogen-activated protein kinase kinase 4

disease_progression

mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors

NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662

G

MET proto-oncogene, receptor tyrosine kinase

severity

protein:increased expression:tumor (human)

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936528:6,217,130...6,349,891
Ensembl chrNW_004936528:6,217,112...6,349,937

G

MIER family member 3

mRNA:increased expression:breast

NCBI chrNW_004936480:11,001,964...11,031,891
Ensembl chrNW_004936480:11,002,583...11,032,329

G

matrix metallopeptidase 13

disease_progression

mRNA, protein:increased expression:tumor:associated with microinvasion during the transition from ductal carcinoma in situ to invasive carcinoma, also expressed in all invasive ductal carcinomas tested

NCBI chrNW_004936551:5,040,084...5,050,384
Ensembl chrNW_004936551:5,040,084...5,050,384

G

nuclear receptor coactivator 4

protein:decreased expression:breast

NCBI chrNW_004936728:376,915...402,539
Ensembl chrNW_004936728:376,852...402,539

G

neurofilament light chain

DNA:loss of heterozygosity

NCBI chrNW_004936757:1,642,122...1,646,499
Ensembl chrNW_004936757:1,642,222...1,645,697

G

NHERF family PDZ scaffold protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:119,808...136,620
Ensembl chrNW_004936594:119,770...136,789

G

notch receptor 3

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429

G

neurotrophic receptor tyrosine kinase 3

mRNA,protein:increased expression:breast:

NCBI chrNW_004936483:13,912,904...14,291,881
Ensembl chrNW_004936483:13,909,109...14,291,887

G

neurotensin

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936507:3,318,982...3,329,248
Ensembl chrNW_004936507:3,318,915...3,329,342

G

proliferating cell nuclear antigen

severity

NCBI chrNW_004936485:13,766,221...13,771,215

G

PHD finger protein 24

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936524:3,020,421...3,031,720
Ensembl chrNW_004936524:3,005,705...3,031,744

G

PML nuclear body scaffold

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936471:33,135,186...33,173,218
Ensembl chrNW_004936471:33,135,164...33,177,666

G

protein kinase C iota

disease_progression

protein:increased expression, altered localization:breast, cytoplasm

NCBI chrNW_004936593:2,170,539...2,236,904
Ensembl chrNW_004936593:2,170,808...2,236,673

G

prostaglandin E receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:3,014,633...3,018,617
Ensembl chrNW_004936659:3,012,012...3,018,275

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936481:3,821,564...3,828,086

G

RAD50 double strand break repair protein

protein:decreased expression:tumor:reduced in 28% vs adjacent or independent normal breast tissue

NCBI chrNW_004936647:2,546,100...2,637,524
Ensembl chrNW_004936647:2,543,599...2,637,846

G

RAD54 like

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936474:27,276,570...27,316,427
Ensembl chrNW_004936474:27,280,573...27,316,428

G

ring finger protein 212

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936477:22,122,854...22,173,324

G

RP1 axonemal microtubule associated

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936496:1,524,123...1,583,114

G

ribosomal RNA processing 1

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936500:475,213...488,475
Ensembl chrNW_004936500:475,178...488,514

G

RUNX family transcription factor 3

disease_progression

DNA:promoter:hypermethylation protein:mislocalization

NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910

G

serpin family B member 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:2,067,796...2,089,965
Ensembl chrNW_004936497:2,069,035...2,089,745

G

SLIT and NTRK like family member 6

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936866:412,719...419,381
Ensembl chrNW_004936866:412,818...419,381

G

SMAD family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

suppressor of cytokine signaling 1

mRNA:increased expression:breast

NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165

G

suppressor of cytokine signaling 2

mRNA:increased expression:breast

NCBI chrNW_004936507:10,013,982...10,015,480
Ensembl chrNW_004936507:10,012,101...10,014,456

G

suppressor of cytokine signaling 3

mRNA:increased expression:breast

NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

spen family transcriptional repressor

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936474:3,473,892...3,535,307
Ensembl chrNW_004936474:3,473,901...3,534,628

G

synaptotagmin 6

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936690:2,435,573...2,497,332
Ensembl chrNW_004936690:2,435,541...2,497,553

G

transmembrane BAX inhibitor motif containing 6

disease_progression

NCBI chrNW_004936512:7,427,926...7,448,700
Ensembl chrNW_004936512:7,427,729...7,449,078

G

tetraspanin 8

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936568:285,130...304,479
Ensembl chrNW_004936568:285,696...311,864

G

thrombospondin type laminin G domain and EAR repeats

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936778:1,576,580...1,660,344
Ensembl chrNW_004936778:1,478,617...1,660,331

G

ubiquitin protein ligase E3 component n-recognin 5

DNA:mutation:CDS:multiple nonsynonymous mutations

NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134

G

vascular endothelial growth factor C

disease_progression

NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559

G

WNT inhibitory factor 1

protein:decreased expression:breast

NCBI chrNW_004936545:3,263,646...3,334,163
Ensembl chrNW_004936545:3,263,623...3,333,937

G

X-ray repair cross complementing 1

susceptibility

DNA:polymorphism: :p.R399Q

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

YEATS domain containing 2

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936578:6,004,427...6,075,414
Ensembl chrNW_004936578:6,006,018...6,075,449

G

zinc finger DBF-type containing 2

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936631:2,649,792...2,686,430
Ensembl chrNW_004936631:2,648,381...2,686,434

G

zinc finger protein 420

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936801:338,743...403,206

G

zinc finger protein 473

ClinVar Annotator: match by term: Breast cancer, invasive ductal

NCBI chrNW_004936889:39,812...56,052
Ensembl chrNW_004936889:41,119...57,582

invasive lobular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Invasive lobular breast carcinoma

PMID:14973102 PMID:25741868 PMID:27257965 PMID:28222693 PMID:28492532 More...

NCBI chrNW_004936472:26,945,659...27,017,693

G

cyclin D1

DNA:amplification:cds (human)
protein:increased expression:breast

PMID:12203362 PMID:12448002

RGD:11353788 RGD:2289133

Ensembl chrNW_004936599:973,838...983,316

G

cyclin D2

DNA:hypermethylation:promoter, breast

NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810

G

CD44 molecule (IN blood group)

mRNA, protein:splice variants, altered localization:breast

NCBI chrNW_004936533:2,949,026...3,033,166

G

cadherin 1

DNA:nonsense mutation: :517insA (human)

PMID:17660459 PMID:18213475

RGD:2289450 RGD:2289492

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

catenin alpha 1

protein:decreased expression:breast

NCBI chrNW_004936531:7,865,907...8,036,020
Ensembl chrNW_004936531:7,865,820...8,037,935

G

catenin beta 1

protein:decreased expression:breast

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

erb-b2 receptor tyrosine kinase 2

severity

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

Fas ligand

protein:increased expression:breast

NCBI chrNW_004936481:14,789,547...14,795,780

Klatskin's tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Klatskin tumor

PMID:25741868 PMID:28492532

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

AT-rich interaction domain 1A

disease_progression

DNA:deletions

NCBI chrNW_004936474:11,148,857...11,197,312

G

GATA binding protein 6

sexual_dimorphism

DNA:mutations

NCBI chrNW_004936550:1,814,336...1,844,399
Ensembl chrNW_004936550:1,814,336...1,844,399

G

lysine methyltransferase 2C

onset

DNA:mutations

NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365

G

KRAS proto-oncogene, GTPase

disease_progression

DNA:mutations

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

sexual_dimorphism

DNA:substitutions, insertion/deletions: (human)

NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346

Krukenberg carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CD44 molecule (IN blood group)

protein:increased expression:ovary

NCBI chrNW_004936533:2,949,026...3,033,166

linitis plastica

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

prostate stem cell antigen

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:9,143,003...9,145,438
Ensembl chrNW_004936470:9,142,327...9,145,722

lung adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily E member 1

severity

mRNA, protein:increased expression:lung (human)

NCBI chrNW_004936535:3,956,490...3,985,002
Ensembl chrNW_004936535:3,955,682...3,985,223

G

acyl-CoA synthetase long chain family member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144

G

ADAM metallopeptidase domain 19

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936515:5,603,095...5,683,347

G

ADAM metallopeptidase domain 28

exacerbates
treatment
disease_progression

protein:increased expression:lung

PMID:20112342 PMID:26800504 PMID:29882245 PMID:30190423

RGD:11531771 RGD:153297792 RGD:153297794 RGD:153297795

NCBI chrNW_004936555:7,615,639...7,660,776
Ensembl chrNW_004936555:7,617,822...7,664,215

G

ADAMTS like 3

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936483:18,191,568...18,523,988
Ensembl chrNW_004936483:18,193,198...18,522,028

G

adhesion G protein-coupled receptor G6

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936625:3,552,611...3,688,281
Ensembl chrNW_004936625:3,552,602...3,688,287

G

adenosylhomocysteinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936561:6,314,797...6,333,961
Ensembl chrNW_004936561:6,314,705...6,334,439

G

aryl hydrocarbon receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588

G

aldo-keto reductase family 1 member A1

disease_progression

NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214

G

ALK receptor tyrosine kinase

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874

G

arachidonate 12-lipoxygenase, 12R type

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985

G

arachidonate 5-lipoxygenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

ALX homeobox 1

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936507:2,775,752...2,797,065
Ensembl chrNW_004936507:2,775,752...2,797,062

G

ALX homeobox 4

disease_progression

NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000

G

anaphase promoting complex subunit 2

severity

mRNA:decreased expression:lung (human)

NCBI chrNW_004936669:797,475...808,952
Ensembl chrNW_004936669:797,318...811,721

G

acidic nuclear phosphoprotein 32 family member A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:28,601,816...28,635,002

G

annexin A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413

G

annexin A5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936662:926,302...959,964
Ensembl chrNW_004936662:925,940...939,451

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

apurinic/apyrimidinic endodeoxyribonuclease 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936877:666,545...669,351
Ensembl chrNW_004936877:666,523...669,338

G

apolipoprotein A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854

G

apolipoprotein C3

protein:altered glycosylation::

NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603

G

aquaporin 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354

G

Rho GTPase activating protein 35

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936664:714,036...788,584
Ensembl chrNW_004936664:713,984...789,344

G

Rho GTPase activating protein 44

mRNA:decreased expression:lung (human)

NCBI chrNW_004936595:5,373,645...5,542,915
Ensembl chrNW_004936595:5,373,476...5,543,073

G

ATP synthase peripheral stalk subunit d

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:354,416...359,415
Ensembl chrNW_004936594:353,980...359,414

G

ATRX chromatin remodeler

disease_progression

NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620

G

axin 2

disease_progression
susceptibility

DNA:SNPs::1712 +19 G>A,148 C>T(human)
DNA:SNP:cds:p.P50S(human)

PMID:16820935 PMID:30346805

RGD:151356655 RGD:151356657

NCBI chrNW_004936541:7,155,963...7,242,466
Ensembl chrNW_004936541:7,211,985...7,242,470

G

alpha-2-glycoprotein 1, zinc-binding

mRNA,protein:increased expression:lung

NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

basic helix-loop-helix family member e41

mRNA:decreased expression:lung (human)

NCBI chrNW_004936548:1,306,939...1,314,678

G

baculoviral IAP repeat containing 3

exacerbates

mRNA:increased expression:B cell (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

ameliorates
disease_progression

mRNA:increased expression:lung (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More...

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

Bruton tyrosine kinase

susceptibility
exacerbates

mRNA:decreased expression:lung (human)

PMID:31803536 PMID:32351880

RGD:151347848 RGD:151347849

NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441

G

basic leucine zipper and W2 domains 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936546:3,160,047...3,215,591
Ensembl chrNW_004936546:3,160,004...3,216,331

G

cell adhesion molecule 1

DNA, mRNA:hypermethylation, decreased expression:promoter:liver

NCBI chrNW_004936542:569,739...883,738
Ensembl chrNW_004936542:565,843...883,609

G

calreticulin

treatment

human cells and recombinant gene in a mouse model

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

capping actin protein, gelsolin like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936712:1,793,666...1,803,621
Ensembl chrNW_004936712:1,793,480...1,806,602

G

chromobox 5

disease_progression

mRNA,protein:increased expression:lung:

NCBI chrNW_004936512:11,441,770...11,480,924
Ensembl chrNW_004936512:11,450,060...11,480,727

G

chromobox 7

mRNA,DNA:decreased expression, loss of heterozygosity:lung:

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

cyclin D1

disease_progression
treatment

PMID:19355812 PMID:26681199

RGD:11536846 RGD:13434927

Ensembl chrNW_004936599:973,838...983,316

G

cyclin D2

disease_progression

NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810

G

chaperonin containing TCP1 subunit 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936643:2,354,799...2,368,048
Ensembl chrNW_004936643:2,354,799...2,368,048

G

CD44 molecule (IN blood group)

disease_progression

mRNA:increased expression:lung (human)
mRNA:splice variants:lung

PMID:18091389 PMID:29537891

RGD:149735539 RGD:2289345

NCBI chrNW_004936533:2,949,026...3,033,166

G

cell division cycle 73

exacerbates

mRNA:decreased expression:lung (human)

NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277

G

cadherin 1

DNA:increased methylation

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

cyclin dependent kinase 12

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936490:14,674,783...14,759,433
Ensembl chrNW_004936490:14,674,800...14,738,818

G

cyclin dependent kinase 4

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More...

NCBI chrNW_004936646:1,886,262...1,889,260

G

cyclin dependent kinase 6

protein:increased expression:lung

NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516

G

chromodomain helicase DNA binding protein 4

susceptibility
ameliorates

DNA:missense mutation:CDS:p.D140E (rs7479004) (human)
mRNA:increased expression:lung (human)
human cells in a mouse model

PMID:28486105 PMID:29667179 PMID:32228507

RGD:151660359 RGD:153323299 RGD:153323307

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

cholinergic receptor nicotinic alpha 3 subunit

susceptibility

DNA:SNP: :rs8042374(human)
associated with smoking; DNA:SNP: :rs1051730(human)
ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:20554942 PMID:24686516 PMID:27993330

RGD:150527848 RGD:151347530

NCBI chrNW_004936471:36,427,598...36,447,903
Ensembl chrNW_004936471:36,427,495...36,457,758

G

cholinergic receptor nicotinic alpha 5 subunit

susceptibility
disease_progression

ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNP: :rs503464(human)
associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
DNA:SNP:cds: p.D398N(human)

PMID:19577767 PMID:20554942 PMID:23314339 PMID:27993330

RGD:150524359 RGD:150527848 RGD:150527849

NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618

G

cholinergic receptor nicotinic beta 4 subunit

DNA:hypomethylation:promoter:
mRNA:increased expression:lung

PMID:20124469 PMID:22945651

RGD:150527851 RGD:151361154

NCBI chrNW_004936471:36,408,471...36,425,571
Ensembl chrNW_004936471:36,408,447...36,426,021

G

CLPTM1 like

susceptibility
no_association
ameliorates

DNA:SNP:: rs4975616(human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)
DNA:SNP:: rs31490(human)
DNA:SNP::rs401681(human)
mRNA:increased expression:lung

PMID:19955392 PMID:22675468 PMID:23738012 PMID:23908149 PMID:24366883 More...

RGD:150530483 RGD:150530485 RGD:150530498 RGD:150530499 RGD:150530502 RGD:150530635 RGD:150537098

NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750

G

cap methyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:22,434,009...22,441,350
Ensembl chrNW_004936475:22,434,180...22,440,846

G

collagen type X alpha 1 chain

disease_progression

mRNA:increased expression:lung

NCBI chrNW_004936824:734,499...741,674
Ensembl chrNW_004936824:734,488...769,010

G

CREB binding protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617

G

colony stimulating factor 1 receptor

protein:increased expression:lung (human)

NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923

G

cysteine and glycine rich protein 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936654:271,067...313,251
Ensembl chrNW_004936654:271,067...289,823

G

catenin beta 1

ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung

PMID:10192393 PMID:25741868 PMID:26619011

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

C-X-C motif chemokine receptor 4

exacerbates

protein:increased expression:lung (human)
mRNA:increased expression:lung (human)

PMID:19716197 PMID:30103827

RGD:152023735 RGD:152177480

NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459

G

discoidin domain receptor tyrosine kinase 2

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139

G

delta like canonical Notch ligand 4

treatment

NCBI chrNW_004936471:4,320,235...4,330,251
Ensembl chrNW_004936471:4,320,933...4,330,253

G

DNA methyltransferase 3 alpha

ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More...

NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610

G

DNA methyltransferase 3 beta

susceptibility

DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human)

NCBI chrNW_004936485:19,547,836...19,570,716

G

docking protein 1

disease_progression

NCBI chrNW_004936556:766,522...769,557
Ensembl chrNW_004936556:766,613...771,316

G

docking protein 2

exacerbates
disease_progression

mRNA:decreased expression:lung (human)

PMID:20139980 PMID:24255704 PMID:30475228

RGD:152177492 RGD:152177493 RGD:152177521

NCBI chrNW_004936555:5,749,787...5,754,149
Ensembl chrNW_004936555:5,750,270...5,753,964

G

docking protein 3

disease_progression

NCBI chrNW_004936597:1,781,129...1,785,998
Ensembl chrNW_004936597:1,781,306...1,785,959

G

DOT1 like histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:1,288,447...1,332,489
Ensembl chrNW_004936588:1,288,392...1,330,297

G

E2F transcription factor 1

mRNA:increased expression:lung

NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026

G

E2F transcription factor 3

NCBI chrNW_004936552:5,712,247...5,783,643
Ensembl chrNW_004936552:5,711,923...5,783,694

G

eukaryotic translation elongation factor 2

exacerbates

protein:increased expression:lung (human)

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

eukaryotic elongation factor 2 kinase

ameliorates

Human cells in mouse model

NCBI chrNW_004936501:7,160,134...7,205,231
Ensembl chrNW_004936501:7,160,134...7,207,377

G

epidermal growth factor

DNA:polymorphism: :p.A61G (human)

NCBI chrNW_004936563:1,058,803...1,181,393

G

epidermal growth factor receptor

disease_progression

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More...

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

euchromatic histone lysine methyltransferase 2

disease_progression

NCBI chrNW_004936727:1,648,451...1,663,294
Ensembl chrNW_004936727:1,648,448...1,663,455

G

eukaryotic translation initiation factor 2B subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936558:1,196,111...1,205,321
Ensembl chrNW_004936558:1,196,068...1,205,867

G

eukaryotic translation initiation factor 2B subunit delta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:5,213,036...5,217,670
Ensembl chrNW_004936493:5,213,055...5,217,664

G

eukaryotic translation initiation factor 2B subunit epsilon

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:5,716,333...5,724,869
Ensembl chrNW_004936578:5,715,512...5,725,096

G

eukaryotic translation initiation factor 3 subunit E

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:36,556,666...36,599,075
Ensembl chrNW_004936470:36,556,599...36,599,264

G

EMAP like 4

CTD Direct Evidence: marker/mechanism

PMID:22980554 PMID:22999080

NCBI chrNW_004936508:9,303,639...9,447,478
Ensembl chrNW_004936508:9,303,639...9,447,548

G

empty spiracles homeobox 2

exacerbates

mRNA,protein:decreased expression:lung (human)

NCBI chrNW_004936486:7,313,689...7,319,971
Ensembl chrNW_004936486:7,313,190...7,319,995

G

enolase 1

CTD Direct Evidence: marker/mechanism

PMID:19381893 PMID:27602772

NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183

G

E1A binding protein p300

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138

G

erb-b2 receptor tyrosine kinase 2

disease_progression

ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 More...

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

erb-b2 receptor tyrosine kinase 3

disease_progression

NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297

G

erb-b2 receptor tyrosine kinase 4

disease_progression

NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035

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ERCC excision repair 1, endonuclease non-catalytic subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745

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ERCC excision repair 6, chromatin remodeling factor

mRNA, protein:increased expression:lung (human)

NCBI chrNW_004936728:706,499...843,447
Ensembl chrNW_004936728:761,804...844,690

G

ERCC excision repair 6 like, spindle assembly checkpoint helicase

exacerbates

mRNA:increased expression:lung (human)

NCBI chrNW_004936959:25,084...30,143

G

ERGIC and golgi 3

disease_progression
ameliorates

mRNA,protein:increased expression:lung (human)

PMID:23374247 PMID:27588471

RGD:151708716 RGD:153323314

NCBI chrNW_004936561:5,256,450...5,270,073
Ensembl chrNW_004936561:5,256,417...5,270,344

G

endoplasmic reticulum protein 29

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936558:4,531,397...4,538,943
Ensembl chrNW_004936558:4,531,471...4,538,943

G

establishment of sister chromatid cohesion N-acetyltransferase 2

ameliorates

NCBI chrNW_004936675:670,915...697,696
Ensembl chrNW_004936675:670,915...697,668

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

disease_progression

NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939

G

Fas cell surface death receptor

mRNA:decreased expression:lung (human)

NCBI chrNW_004936735:209,369...234,582

G

fatty acid synthase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:5,591,785...5,609,886
Ensembl chrNW_004936594:5,592,609...5,608,972

G

fibrillarin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936661:2,444,985...2,455,423
Ensembl chrNW_004936661:2,444,866...2,455,528

G

FES proto-oncogene, tyrosine kinase

treatment

human cells in a mouse model

NCBI chrNW_004936483:16,123,938...16,135,044
Ensembl chrNW_004936483:16,123,779...16,135,044

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fibroblast growth factor 10

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898

G

fibroblast growth factor 18

mRNA:decreased expression:lung (human)

NCBI chrNW_004936609:3,677,661...3,706,511
Ensembl chrNW_004936609:3,677,237...3,706,517

G

fibroblast growth factor 9

disease_progression

mRNA:decreased expression:lung (human)
protein:increased expression:lung (human)

PMID:19296538 PMID:19358281 PMID:20464547

RGD:150429981 RGD:152177688 RGD:152975620

NCBI chrNW_004936720:282,291...316,629
Ensembl chrNW_004936720:279,521...316,674

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fibroblast growth factor receptor 4

disease_progression
exacerbates

DNA:SNP:exon 9: p.G388R (human)
human cells in mouse model
DNA:SNP:exon 9: p.G388R (rs351855)(human)

PMID:16061909 PMID:19296538 PMID:29402970

RGD:150429976 RGD:150429981 RGD:150429984

NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758

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FKBP prolyl isomerase 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:6,731,942...6,736,677
Ensembl chrNW_004936512:6,731,942...6,735,456

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fms related receptor tyrosine kinase 1

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041

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forkhead box A1

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung

PMID:12234996 PMID:29072684 PMID:34254728

RGD:151665758 RGD:151665822

NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224

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forkhead box O3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837

G

forkhead box P1

mRNA:decreased expression:lung (rat)

NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324

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forkhead box P2

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936589:4,120,162...4,661,258
Ensembl chrNW_004936589:4,123,182...4,382,005

G

forkhead box P4

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199

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frizzled related protein

severity

mRNA:decreased expression:lung (human)

NCBI chrNW_004936509:11,440,414...11,471,042
Ensembl chrNW_004936509:11,440,148...11,470,967

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far upstream element binding protein 1

mRNA:decreased expression:lung (human)

NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942

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glyceraldehyde-3-phosphate dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936709:1,243,149...1,247,782
Ensembl chrNW_004936709:1,243,147...1,247,903

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GAR1 ribonucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936563:1,006,475...1,014,808
Ensembl chrNW_004936563:1,006,517...1,014,808

G

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:8,750,928...8,782,303
Ensembl chrNW_004936500:8,753,463...8,786,236

G

gap junction protein beta 2

DNA, mRNA:hypermethylation, decreased expression:lung

NCBI chrNW_004936720:1,528,205...1,530,296
Ensembl chrNW_004936720:1,528,249...1,528,929

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G protein subunit gamma 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936803:57,659...62,005
Ensembl chrNW_004936803:57,151...62,047

G

glucosamine-phosphate N-acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936697:2,079,396...2,087,602
Ensembl chrNW_004936697:2,079,470...2,086,877

G

golgi membrane protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936680:1,463,991...1,528,322

G

glucose-6-phosphate isomerase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936570:1,582,120...1,608,537
Ensembl chrNW_004936570:1,579,372...1,608,788

G

glutathione peroxidase 3

mRNA:decreased expression:lung (human)

NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498

G

glutamate rich WD repeat containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936664:2,548,178...2,555,234
Ensembl chrNW_004936664:2,547,789...2,555,887

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helicase, lymphoid specific

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936601:626,354...662,477
Ensembl chrNW_004936601:626,823...662,465

G

hexokinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936521:9,067,062...9,139,112
Ensembl chrNW_004936521:9,066,999...9,159,793

G

hexokinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936556:1,054,143...1,113,425
Ensembl chrNW_004936556:1,054,021...1,113,450

G

high mobility group box 2

CTD Direct Evidence: marker/mechanism

PMID:24366584 PMID:27602772

NCBI chrNW_004936516:4,536,664...4,539,331
Ensembl chrNW_004936516:4,534,306...4,539,387

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heterogeneous nuclear ribonucleoprotein A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:11,481,017...11,487,737

G

homeobox B7

severity

protein:increased expression:lung epithelium (human)

NCBI chrNW_004936490:12,777,005...12,780,515
Ensembl chrNW_004936490:12,777,020...12,780,522

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HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

hydroxysteroid 17-beta dehydrogenase 10

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936751:399,743...402,200
Ensembl chrNW_004936751:399,701...402,344

G

heat shock protein 90 beta family member 1

mRNA:increased expression:lung (human)

NCBI chrNW_004936492:10,513,908...10,528,281
Ensembl chrNW_004936492:10,513,908...10,528,285

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heat shock protein family B (small) member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186

G

5-hydroxytryptamine receptor 4

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936504:6,146,974...6,306,000
Ensembl chrNW_004936504:6,146,974...6,265,631

G

HtrA serine peptidase 1

disease_progression

human cells in mouse model

NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739

G

isocitrate dehydrogenase (NADP(+)) 1

disease_progression

mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
protein:increased expression:blood plasma (human)

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

RGD:149735539 RGD:149735540

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

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isocitrate dehydrogenase (NADP(+)) 2

severity

protein:increased expression:blood serum (human)
protein:increased expression:lung (human)

PMID:29465809 PMID:30128035

RGD:149735564 RGD:149735567

NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341

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insulin like growth factor 2 receptor

mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat)

NCBI chrNW_004936489:11,447,043...11,523,695
Ensembl chrNW_004936489:11,447,038...11,524,174

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IKAROS family zinc finger 1

exacerbates
ameliorates

protein:increased expression:lung (human)
mRNA:increased expression:lung (human)

PMID:32787735 PMID:33738286

RGD:150540324 RGD:151347632

NCBI chrNW_004936686:1,459,582...1,556,478
Ensembl chrNW_004936686:1,462,145...1,556,451

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interleukin 1 receptor type 2

severity
disease_progression

mRNA:increased expression:lung (human)
mRNA:altered expression:lung (human)

PMID:29942094 PMID:31921619

RGD:152998982 RGD:152998998

NCBI chrNW_004936713:679,680...716,801
Ensembl chrNW_004936713:701,155...716,650

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inosine monophosphate dehydrogenase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:748,777...753,582
Ensembl chrNW_004936529:745,511...753,581

G

importin 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936722:359,741...370,514
Ensembl chrNW_004936722:360,250...373,400

G

importin 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:12,231,970...12,271,639
Ensembl chrNW_004936472:12,229,922...12,271,964

G

IQ motif and Sec7 domain ArfGEF 1

disease_progression

NCBI chrNW_004936898:318,564...425,785
Ensembl chrNW_004936898:337,400...425,859

G

interleukin 1 receptor associated kinase 3

mRNA:increased expression:lung (human)

NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806

G

iron responsive element binding protein 2

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636

G

Janus kinase 2

treatment

human cells in mouse model

NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867

G

JunB proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123

G

potassium inwardly rectifying channel subfamily J member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:2,865,803...2,867,657
Ensembl chrNW_004936492:2,865,879...2,867,201

G

KLF transcription factor 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936511:7,806,714...7,824,833
Ensembl chrNW_004936511:7,806,708...7,824,992

G

lysine methyltransferase 2C

onset
disease_progression

PMID:30821106 PMID:32867667

RGD:151356760 RGD:151356761

NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365

G

karyopherin subunit alpha 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936541:5,217,389...5,228,816
Ensembl chrNW_004936541:5,217,362...5,228,846

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of lung
ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:2278970 PMID:3122217 PMID:6320174 PMID:11745231 PMID:12460918 More...

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

lactate dehydrogenase A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936528:866,607...879,977

G

leukocyte cell derived chemotaxin 2

ameliorates

human cells in mouse model

NCBI chrNW_004936597:3,051,143...3,057,383
Ensembl chrNW_004936597:3,051,143...3,057,383

G

lamin A/C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:5,374,208...5,395,442
Ensembl chrNW_004936580:5,373,974...5,395,468

G

lamin B1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936504:157,459...211,916
Ensembl chrNW_004936504:157,453...211,967

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

ameliorates

DNA:hypomethylation:promoter (human)
mRNA:decreased expression:lung (human)
human cell line in a mouse model

PMID:24736069 PMID:25519225 PMID:27793774

RGD:151361181 RGD:151665173 RGD:151665499

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

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RNA polymerase I and III subunit D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936472:22,841,094...22,842,798
Ensembl chrNW_004936472:22,841,094...22,881,713

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cytochrome P450 1B1

protein:increased expression:lung (human)

NCBI chrNW_004936663:345,021...355,188
Ensembl chrNW_004936663:348,368...355,191

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serotransferrin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:6,917,762...6,947,512
Ensembl chrNW_004936529:6,855,958...6,947,394

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delta-1-pyrroline-5-carboxylate synthase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936636:3,779,259...3,800,846
Ensembl chrNW_004936636:3,760,326...3,801,073

G

LDL receptor related protein 1B

disease_progression

DNA:mutations:multiple: (human)

NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Adenocarcinoma of lung
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More...

NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083

G

mitogen-activated protein kinase kinase 1

ClinVar Annotator: match by term: Adenocarcinoma of lung
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)

ClinVar
CTD
RGD

PMID:22135231 PMID:26619011 PMID:29254206

NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302

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mitogen-activated protein kinase kinase 4

severity

PMID:12231543 PMID:21896780

RGD:150429783 RGD:150429821

NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662

G

mitogen-activated protein kinase kinase 7

exacerbates

human gene in a mouse model

NCBI chrNW_004936588:4,882,191...4,891,807
Ensembl chrNW_004936588:4,882,184...4,892,071

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mitogen-activated protein kinase kinase kinase 8

exacerbates

NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892

G

mitogen-activated protein kinase kinase kinase kinase 4

exacerbates
ameliorates

mRNA, protein:increased expression:lung (human)
human cell line in a mouse model

PMID:22824148 PMID:28306189 PMID:33510968

RGD:151347677 RGD:151347678 RGD:151347681

NCBI chrNW_004936713:515,388...616,024
Ensembl chrNW_004936713:435,238...612,835

G

mitogen-activated protein kinase 14

exacerbates

mRNA:increased expression:lung (human)

NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232

G

MCL1 apoptosis regulator, BCL2 family member

severity
treatment

mRNA:increased expression:lung (human)
human cells in mouse model

NCBI chrNW_004936580:803,452...806,966
Ensembl chrNW_004936580:804,903...806,796

G

mesenchyme homeobox 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004936541:216,390...238,153
Ensembl chrNW_004936541:217,193...236,031

G

MIER family member 3

ameliorates

NCBI chrNW_004936480:11,001,964...11,031,891
Ensembl chrNW_004936480:11,002,583...11,032,329

G

marker of proliferation Ki-67

disease_progression

protein:altered expression:lung (human)

NCBI chrNW_004936486:15,561,327...15,587,109

G

mutL homolog 1

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736

G

MRE11 homolog, double strand break repair nuclease

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936674:466,495...528,072
Ensembl chrNW_004936674:466,456...530,317

G

mitochondrial ribosomal protein L12

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:5,301,846...5,305,362
Ensembl chrNW_004936594:5,301,866...5,305,362

G

mitochondrial ribosomal protein S5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004937185:25,998...39,685

G

membrane spanning 4-domains A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936581:2,466,294...2,477,530
Ensembl chrNW_004936581:2,466,312...2,477,530

G

mutS homolog 2

no_association

DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)
DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)

NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356

G

mutS homolog 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561

G

mutS homolog 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787

G

mucin 1, cell surface associated

mRNA:increased expression:lung

NCBI chrNW_004936580:4,691,870...4,694,092

G

mucin 4, cell surface associated

disease_progression

protein:increased expression:trachea

NCBI chrNW_004936784:515,608...539,915

G

mucin 5AC, oligomeric mucus/gel-forming

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936816:129,926...159,396

G

MYC proto-oncogene, bHLH transcription factor

human cell line in mouse model
CTD Direct Evidence: marker/mechanism

PMID:20033209 PMID:26656844 PMID:27602772

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

MYD88 innate immune signal transduction adaptor

ameliorates
treatment

mouse cell line in a mouse model

PMID:30712876 PMID:32140881

RGD:150520172 RGD:150540309

NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372

G

N-alpha-acetyltransferase 10, NatA catalytic subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936809:812,454...817,226
Ensembl chrNW_004936809:812,390...817,288

G

NLR family apoptosis inhibitory protein

ameliorates

mRNA:increased expression:lung (human)

NCBI chrNW_004936549:5,000,526...5,069,110

G

non-SMC condensin I complex subunit G

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936477:10,408,347...10,445,361
Ensembl chrNW_004936477:10,405,997...10,445,206

G

NK2 homeobox 1

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566

G

NLR family pyrin domain containing 3

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936864:709,693...732,119
Ensembl chrNW_004936864:709,709...731,718

G

NOP56 ribonucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936485:16,038,090...16,043,408
Ensembl chrNW_004936485:16,038,182...16,043,357

G

NOP58 ribonucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936726:1,457,038...1,487,374
Ensembl chrNW_004936726:1,457,002...1,486,530

G

notch receptor 1

treatment

NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428

G

nucleophosmin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936609:3,712,628...3,725,635

G

nucleophosmin/nucleoplasmin 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936600:3,997,549...3,999,620
Ensembl chrNW_004936600:3,997,285...3,999,630

G

nudix hydrolase 21

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:8,739,992...8,759,165
Ensembl chrNW_004936475:8,741,821...8,759,223

G

NUF2 component of NDC80 kinetochore complex

disease_progression

NCBI chrNW_004936481:21,342,667...21,371,311
Ensembl chrNW_004936481:21,342,786...21,371,328

G

8-oxoguanine DNA glycosylase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

poly(A) binding protein cytoplasmic 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:21,453,244...21,468,059
Ensembl chrNW_004936474:21,452,005...21,468,065

G

parkin coregulated

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936489:13,328,143...13,787,329
Ensembl chrNW_004936489:13,328,078...13,787,344

G

pterin-4 alpha-carbinolamine dehydratase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936521:7,843,945...7,847,827
Ensembl chrNW_004936521:7,845,870...7,848,426

G

phosphatidylinositol glycan anchor biosynthesis class N

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936497:3,121,184...3,230,912
Ensembl chrNW_004936497:3,124,557...3,234,061

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phosphoinositide-3-kinase regulatory subunit 1

mRNA:decreased expression:lung

NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537

G

paired like homeodomain 2

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936563:1,713,294...1,732,431

G

phospholipase C gamma 1

exacerbates

protein:decreased expression:lung (human)

NCBI chrNW_004936561:598,372...631,575
Ensembl chrNW_004936561:598,382...631,581

G

procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

disease_progression

NCBI chrNW_004936519:9,053,192...9,139,221
Ensembl chrNW_004936519:9,053,033...9,140,059

G

DNA polymerase delta 1, catalytic subunit

exacerbates

protein:increased expression:lung (human)

NCBI chrNW_004936889:231,373...250,985
Ensembl chrNW_004936889:231,373...250,987
Ensembl chrNW_004936889:231,373...250,987

G

peter pan homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:499,447...503,316
Ensembl chrNW_004936659:499,536...503,162

G

protein phosphatase 3 catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540

G

PRAME nuclear receptor transcriptional regulator

mRNA:decreased expression:lung (human)

NCBI chrNW_004936619:1,748,337...1,751,748

G

PR/SET domain 1

exacerbates

NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683

G

parkin RBR E3 ubiquitin protein ligase

ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:10072423 PMID:12719539 PMID:20301651 PMID:22956510 PMID:25741868 More...

NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872

G

phosphoserine aminotransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936632:4,392,165...4,422,670
Ensembl chrNW_004936632:4,391,459...4,423,264

G

patched 1

ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:27993330 PMID:28492532

NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

protein tyrosine phosphatase non-receptor type 13

exacerbates
susceptibility

mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)

PMID:19672627 PMID:22245727 PMID:33536603

RGD:152176663 RGD:152176665 RGD:152975626

NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001

G

protein tyrosine phosphatase receptor type B

disease_progression

mRNA:altered expression:lung (human)
mRNA:decreased expression:lung (human)

PMID:7981622 PMID:29254206

RGD:151665107 RGD:151665112

NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715

G

protein tyrosine phosphatase receptor type J

susceptibility

DNA:missense mutations:cds:p.R326Q, p.Q276P (human)

NCBI chrNW_004936562:1,161,764...1,234,800
Ensembl chrNW_004936562:1,165,304...1,211,817

G

Rac family small GTPase 1

exacerbates
ameliorates

mRNA:increased expression:lung (human)

PMID:31779616 PMID:32366477

RGD:152998910 RGD:153345550

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

Raf-1 proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More...

NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096

G

RAN guanine nucleotide release factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:1,513,855...1,515,300
Ensembl chrNW_004936595:1,513,180...1,517,270

G

retinoic acid receptor beta

DNA:hypomethylation:lung

NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885

G

RAS p21 protein activator 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:5,839,560...5,933,049
Ensembl chrNW_004936469:5,839,743...5,932,021

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846

G

RNA binding motif protein 10

mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple

PMID:22980975 PMID:29085465 PMID:30955253

RGD:11097386 RGD:151356983 RGD:151356984

NCBI chrNW_004936502:12,923,890...12,952,179
Ensembl chrNW_004936502:12,925,910...12,955,470

G

RNA terminal phosphate cyclase like 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936503:375,191...450,596
Ensembl chrNW_004936503:373,934...450,596

G

replication factor C subunit 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:3,204,035...3,219,806

G

Ras and Rab interactor 3

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936733:683,309...765,897
Ensembl chrNW_004936733:683,272...765,906

G

ribonuclease H2 subunit A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:1,897,777...1,905,526
Ensembl chrNW_004936659:1,897,769...1,905,457

G

ring finger protein 43

severity

human cells in a mouse model

NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828

G

ROS proto-oncogene 1, receptor tyrosine kinase

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936658:382,025...506,818
Ensembl chrNW_004936658:382,261...506,818

G

ribosomal protein L10a

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:23,779,144...23,781,560
Ensembl chrNW_004936476:23,779,140...23,781,563

G

ribosomal protein L13a

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936664:3,352,535...3,356,196
Ensembl chrNW_004936664:3,352,514...3,356,895

G

ribosomal protein L27a

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936528:9,343,620...9,348,935
Ensembl chrNW_004936528:9,346,592...9,348,482

G

ribosomal protein L36a

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936813:467,505...470,673

G

ribosomal protein SA

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:28,624,110...28,628,488

G

ribonucleotide reductase catalytic subunit M1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793

G

ribonucleotide reductase regulatory subunit M2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936532:6,348,041...6,390,144

G

ribosome biogenesis regulator 1 homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936496:7,563,989...7,565,663
Ensembl chrNW_004936496:7,564,459...7,565,556

G

SATB homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:10,906,059...11,001,007
Ensembl chrNW_004936473:10,904,989...11,001,051

G

syndecan 1

mRNA:increased expression:lung (human)

NCBI chrNW_004936493:11,177,804...11,199,678
Ensembl chrNW_004936493:11,177,708...11,199,804

G

serpin family A member 3

protein:increased expression:cytoplasm

NCBI chrNW_004936846:174,411...182,053
Ensembl chrNW_004936846:174,233...182,203

G

SET domain containing 2, histone lysine methyltransferase

ameliorates
exacerbates
severity

human cells and genes in mouse model
DNA:mutations:multiple (human)

PMID:27687306 PMID:28202515 PMID:33223508 PMID:33707235

RGD:126848875 RGD:150429633 RGD:150429648 RGD:150429649

NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373

G

stratifin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433

G

surfactant protein C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011

G

sideroflexin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936609:727,621...754,806
Ensembl chrNW_004936609:729,589...754,774

G

serine hydroxymethyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936741:1,849,239...1,877,724
Ensembl chrNW_004936741:1,849,609...1,877,727

G

solute carrier family 15 member 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936536:8,280,537...8,316,011
Ensembl chrNW_004936536:8,280,448...8,316,064

G

solute carrier family 19 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936778:823,376...846,843
Ensembl chrNW_004936778:829,550...848,833

G

solute carrier family 1 member 5

disease_progression

NCBI chrNW_004936664:599,012...610,689
Ensembl chrNW_004936664:598,468...610,698

G

solute carrier family 3 member 2

disease_progression

NCBI chrNW_004936581:424,801...441,592

G

solute carrier family 4 member 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936598:3,391,587...3,713,629
Ensembl chrNW_004936598:3,391,575...3,713,635

G

solute carrier family 4 member 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:18,550,489...18,645,470
Ensembl chrNW_004936473:18,550,484...18,645,628

G

solute carrier family 67 member 1

disease_progression

mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:27993330 PMID:32726996

NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345

G

solute carrier family 7 member 5

disease_progression

PMID:19171406 PMID:26279756

RGD:151361150 RGD:151361151

NCBI chrNW_004936641:1,513,110...1,538,955

G

SMAD family member 4

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More...

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038

G

small nuclear ribonucleoprotein polypeptides B and B1

severity

mRNA:increased expression:lung (human)

NCBI chrNW_004936485:16,142,231...16,161,761
Ensembl chrNW_004936485:16,157,485...16,163,698

G

small nuclear ribonucleoprotein polypeptide E

severity

mRNA:increased expression:lung (human)

NCBI chrNW_004936567:849,300...855,214
Ensembl chrNW_004936567:849,397...855,187

G

small nuclear ribonucleoprotein polypeptide G

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:14,442,904...14,450,717
Ensembl chrNW_004936491:14,443,026...14,450,631

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

SOS Ras/Rac guanine nucleotide exchange factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936508:12,162,553...12,281,812
Ensembl chrNW_004936508:12,162,547...12,281,820

G

SRY-box transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613

G

SRY-box transcription factor 30

disease_progression

NCBI chrNW_004936515:5,501,315...5,537,946
Ensembl chrNW_004936515:5,458,393...5,537,946

G

speckle type BTB/POZ protein

ameliorates

human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)

PMID:30607139 PMID:31105033

RGD:153298920 RGD:153298927

NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155

G

SRC proto-oncogene, non-receptor tyrosine kinase

severity

NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483

G

spermidine synthase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:121,135...124,894
Ensembl chrNW_004936474:118,000...124,963

G

serine racemase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936538:8,362,033...8,383,820

G

serine and arginine rich splicing factor 1

severity

NCBI chrNW_004936490:5,055,258...5,059,118
Ensembl chrNW_004936490:5,055,253...5,059,116

G

serine and arginine rich splicing factor 2

severity

NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164

G

serine/threonine kinase 11

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936588:579,816...601,033
Ensembl chrNW_004936588:579,816...603,654

G

serine/threonine kinase 39

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:11,274,398...11,516,244
Ensembl chrNW_004936469:11,274,409...11,516,752

G

spermatid perinuclear RNA binding protein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:11,579,002...11,647,078
Ensembl chrNW_004936487:11,592,008...11,647,098

G

succinate-CoA ligase GDP-forming subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936603:243,113...378,526
Ensembl chrNW_004936603:243,113...378,528

G

telomerase reverse transcriptase

susceptibility

DNA:SNP:: rs2736100(human)
DNA:SNP::rs33963617(human)
DNA:SNPs:: rs2853669,rs2736108(human)
DNA:SNP: :rs2736098(human)

PMID:19955392 PMID:23738012 PMID:23908149 PMID:24761905 PMID:31935503

RGD:150530485 RGD:150530498 RGD:150530502 RGD:150530628 RGD:150530635

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

transforming growth factor beta 2

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007

G

translocase of inner mitochondrial membrane 10

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936581:4,972,241...4,975,092
Ensembl chrNW_004936581:4,972,178...4,975,189

G

translocase of inner mitochondrial membrane 8A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936813:425,613...428,722
Ensembl chrNW_004936813:425,613...428,702

G

TIMP metallopeptidase inhibitor 3

mRNA:decreased expression:lung (human)

NCBI chrNW_004936492:6,996,627...7,046,137
Ensembl chrNW_004936492:6,996,613...7,046,190

G

thymidine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936594:2,784,891...2,794,693
Ensembl chrNW_004936594:2,784,226...2,794,830

G

toll like receptor 4

ClinVar Annotator: match by term: Lung adenocarcinoma

NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

NCBI chrNW_004936593:212,642...230,645
Ensembl chrNW_004936593:212,532...230,651

G

translocase of outer mitochondrial membrane 40

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936706:1,500,244...1,510,328

G

DNA topoisomerase II alpha

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978

G

tumor protein p53

ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma

PMID:1565144 PMID:1631137 PMID:2046748 PMID:7732013 PMID:8423216 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor protein p63

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:492,267...705,282
Ensembl chrNW_004936578:491,507...705,729

G

triosephosphate isomerase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936709:948,151...951,430
Ensembl chrNW_004936709:945,201...951,441

G

TNF receptor associated factor 4

mRNA:increased expression:lung (human)

NCBI chrNW_004936538:4,952,627...4,958,696

G

transcription termination factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:18,956,364...18,983,850
Ensembl chrNW_004936487:18,956,899...18,983,888

G

transthyretin

mRNA,protein:increased expression:lung (human)

NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566

G

thymidylate synthetase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840

G

ubiquitin protein ligase E3 component n-recognin 5

ameliorates

human cell line in a mouse model

NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134

G

uridine-cytidine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936481:19,505,477...19,560,035
Ensembl chrNW_004936481:19,505,459...19,560,083

G

vav guanine nucleotide exchange factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:4,058,312...4,107,330
Ensembl chrNW_004936588:4,058,343...4,107,109

G

WD repeat containing antisense to TP53

severity

NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791

G

XPC complex subunit, DNA damage recognition and repair factor

CTD Direct Evidence: marker/mechanism

PMID:21327329 PMID:27777383

NCBI chrNW_004936602:118,173...139,884
Ensembl chrNW_004936602:118,188...139,675

G

exportin 1

exacerbates

mRNA:increased expression:lung (human)
circRNA:increased expression:lung (human)

PMID:23639940 PMID:33268793

RGD:151665799 RGD:151665801

NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343

G

X-ray repair cross complementing 1

susceptibility
severity

DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)

PMID:11104903 PMID:20003463

RGD:151347406 RGD:151347422

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

X-ray repair cross complementing 5

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936586:1,055,478...1,137,924
Ensembl chrNW_004936586:1,055,335...1,137,984

G

X-ray repair cross complementing 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:303,843...325,812
Ensembl chrNW_004936492:300,057...325,845

G

zinc finger homeobox 3

ameliorates

DNA:mutations:multiple (human)

NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544

Lung Carcinoid Tumors

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATRX chromatin remodeler

disease_progression

protein:decreased expression:nucleus, lung

NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620

G

collagen type IV alpha 3 chain

severity

mRNA:decreased expression:lung (human)

NCBI chrNW_004936525:8,642,744...8,774,975

G

cAMP responsive element binding protein 5

severity

mRNA:decreased expression:lung (human)

NCBI chrNW_004936478:5,184,157...5,319,176
Ensembl chrNW_004936478:4,924,489...5,319,844

G

menin 1

ClinVar Annotator: match by term: Lung carcinoid tumor

PMID:9215689 PMID:9361035 PMID:9463336 PMID:9709921 PMID:10595737 More...

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

protein tyrosine phosphatase receptor type B

severity

mRNA:decreased expression:lung (human)

NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715

mammary Paget's disease

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

erb-b2 receptor tyrosine kinase 2

DNA:amplification

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

mixed fibrolamellar hepatocellular carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

protein kinase cAMP-activated catalytic subunit alpha

susceptibility

NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753

mucinous adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

homeobox D9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936509:5,609,744...5,611,943
Ensembl chrNW_004936509:5,609,744...5,611,943

G

mucin 1, cell surface associated

associated with Pancreatic Diseases

NCBI chrNW_004936580:4,691,870...4,694,092

G

mucin 2, oligomeric mucus/gel-forming

associated with cholangiocarcinoma;mRNA,protein:increased expression:bile duct
associated with pancreatic diseases;protein:increased expression:pancreas
associated with pancreatic neoplasms;protein:increased expression:pancreas
associated Pancreatic Neoplasms;protein:increased expression:pancreas

PMID:12717243 PMID:15048136 PMID:17708554 PMID:19954814

RGD:2317985 RGD:2324868 RGD:2324887 RGD:2324889

NCBI chrNW_004936816:60,499...91,628
Ensembl chrNW_004936816:60,499...91,628

G

mucin 4, cell surface associated

severity

associated with pancreatic disease;protein:increased expression:pancreas

NCBI chrNW_004936784:515,608...539,915

G

mucin 5AC, oligomeric mucus/gel-forming

disease_progression

associated with pancreatic neoplasms;protein:increased expression:pancreas
associated with pancreatic diseases;protein:decreased expression:pancreas
associated with pancreatic neoplasms; mRNA:increased expression:pancreas

PMID:10227724 PMID:17708554 PMID:19954814

RGD:2324887 RGD:2324889 RGD:2324907

NCBI chrNW_004936816:129,926...159,396

G

mucin 6, oligomeric mucus/gel-forming

associated with bile duct neoplasms; protein:increased expression:bile duct

NCBI chrNW_004936816:882...14,717

G

zinc finger homeobox 3

protein:increased expression:colon, nucleus, cytoplasm (human)

NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544

mucinous cystadenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

luteinizing hormone/choriogonadotropin receptor

mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.01)

NCBI chrNW_004936508:3,928,467...3,983,481
Ensembl chrNW_004936508:3,928,466...3,983,890

G

serum/glucocorticoid regulated kinase 1

mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.01)

NCBI chrNW_004936560:1,979,804...2,009,167
Ensembl chrNW_004936560:1,979,808...2,088,329

nasal cavity adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

clusterin

NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836

nonpapillary renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

calcium/calmodulin dependent protein kinase I

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

NCBI chrNW_004936602:3,402,559...3,413,323
Ensembl chrNW_004936602:3,401,005...3,414,935

G

folliculin

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

PMID:12204536 PMID:12471204 PMID:15852235 PMID:16199547 PMID:17496196 More...

NCBI chrNW_004936741:881,150...901,296
Ensembl chrNW_004936741:880,736...901,468

G

HNF1 homeobox A

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

PMID:8945470 PMID:9075818 PMID:9112026 PMID:9133564 PMID:9287053 More...

NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505

G

HNF1 homeobox B

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

PMID:9398836 PMID:12148114 PMID:14583183 PMID:15068978 PMID:15660195 More...

NCBI chrNW_004936490:649,551...702,448
Ensembl chrNW_004936490:649,546...702,672

G

8-oxoguanine DNA glycosylase

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

von Hippel-Lindau tumor suppressor

ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma

PMID:8956040 PMID:9058738 PMID:9399847 PMID:9536098 PMID:9671762 More...

NCBI chrNW_004936602:3,135,790...3,140,622

oncocytic carcinoma of the thyroid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

chromobox 7

protein:decreased expression:thyroid Human)

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

NADH:ubiquinone oxidoreductase subunit A13

ClinVar Annotator: match by term: Hurthle cell carcinoma of the thyroid | ClinVar Annotator: match by term: NDUFA13-related condition

PMID:15841082 PMID:25741868 PMID:28492532

NCBI chrNW_004936596:1,946,058...1,953,734
Ensembl chrNW_004936596:1,946,111...1,953,698

G

proteasome 20S subunit beta 9

NCBI chrNW_004936476:25,894,313...25,899,132
Ensembl chrNW_004936476:25,894,027...25,899,319

ovarian serous cystadenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

baculoviral IAP repeat containing 3

exacerbates

mRNA:increased expression:ovary (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

ovary adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin D3

disease_progression

NCBI chrNW_004936476:17,799,754...17,886,835
Ensembl chrNW_004936476:17,879,869...17,886,827

G

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

mRNA:increased expression:ovary (human)

NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185

G

PRAME nuclear receptor transcriptional regulator

severity

mRNA, protein:increased expression:female gonad (human)

NCBI chrNW_004936619:1,748,337...1,751,748

ovary serous adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AT-rich interaction domain 1A

ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary

NCBI chrNW_004936474:11,148,857...11,197,312

G

BRCA1 DNA repair associated

ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma

PMID:16084575 PMID:16455195 PMID:16949048 PMID:17100994 PMID:19656164 More...

NCBI chrNW_004936490:17,735,444...17,801,456

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma

PMID:16793542 PMID:18704680 PMID:25741868

NCBI chrNW_004936472:26,945,659...27,017,693

G

basigin (Ok blood group)

protein:increased expression:ovary

NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary

PMID:7773929 PMID:8439212 PMID:12720172 PMID:15093544 PMID:15696205 More...

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

tumor protein p53

DNA, protein:loss of heterozygosity, increased expression:ovary

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

pancreatic acinar cell adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

DNA:missense mutation, gene fusions:multiple (human)

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483

pancreatic adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 3

severity

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936526:6,944,056...7,201,226
Ensembl chrNW_004936526:6,944,005...7,200,583

G

baculoviral IAP repeat containing 2

exacerbates

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936551:5,515,904...5,535,864

G

baculoviral IAP repeat containing 3

disease_progression

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

exacerbates

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

baculoviral IAP repeat containing 7

exacerbates

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

carbonyl reductase 4

ClinVar Annotator: match by term: Pancreatic adenocarcinoma

PMID:9536098 PMID:17576681 PMID:25741868 PMID:28166811 PMID:28492532

NCBI chrNW_004936516:1,184,859...1,205,668
Ensembl chrNW_004936516:1,181,524...1,205,760

G

cyclin D1

severity

protein:increased expression:pancreas (human)

Ensembl chrNW_004936599:973,838...983,316

G

cyclin dependent kinase 4

treatment

human cells in a mouse model

NCBI chrNW_004936646:1,886,262...1,889,260

G

cyclin dependent kinase 6

treatment

human cells in a mouse model

NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516

G

C-X-C motif chemokine receptor 4

NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459

G

E2F transcription factor 1

treatment

Human cells in a mouse model

NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026

G

histidine rich glycoprotein

disease_progression

NCBI chrNW_004936578:3,285,986...3,295,876
Ensembl chrNW_004936578:3,285,986...3,295,876

G

Janus kinase 1

treatment

human cell line in a mouse model

NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132

G

adhesion G protein-coupled receptor B1

mRNA:decreased expression:pancreas

NCBI chrNW_004936470:9,247,749...9,313,230
Ensembl chrNW_004936470:9,248,319...9,313,230

G

mitogen-activated protein kinase kinase 1

treatment
severity

human tissue in a mouse model
protein:increased expression:pancreas (human)

PMID:19513748 PMID:28849200

RGD:13838804 RGD:13838840

NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302

G

mitogen-activated protein kinase 1

severity

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

mitogen-activated protein kinase 10

severity

DNA:SNP:intron: (rs2589506) (human)

NCBI chrNW_004936896:228,908...539,836
Ensembl chrNW_004936896:230,494...540,071

G

mitogen-activated protein kinase 8

exacerbates

protein:increased phosphorylation:pancreas (human)

NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907

G

mitogen-activated protein kinase 9

NCBI chrNW_004936739:551,678...602,027
Ensembl chrNW_004936739:551,629...602,047

G

nuclear factor kappa B subunit 1

severity

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435

G

palladin, cytoskeletal associated protein

ClinVar Annotator: match by term: Pancreatic adenocarcinoma

PMID:9536098 PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 More...

NCBI chrNW_004936516:786,358...1,151,910
Ensembl chrNW_004936516:802,484...1,151,801

G

plasminogen activator, tissue type

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321

G

Rac family small GTPase 1

treatment

human cells in a mouse model

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

human cells in a mouse model

NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096

G

RAS like proto-oncogene B

treatment

human cells in a mouse model

NCBI chrNW_004936469:50,237,804...50,279,483
Ensembl chrNW_004936469:50,236,409...50,279,583

G

ralA binding protein 1

treatment

human cells in a mouse model

NCBI chrNW_004936626:1,832,703...1,851,486
Ensembl chrNW_004936626:1,832,584...1,851,467

G

SMAD family member 7

severity

human cell and construct in a mouse model

NCBI chrNW_004936497:13,894,586...13,921,978
Ensembl chrNW_004936497:13,894,580...13,922,065

G

signal transducer and activator of transcription 1

ameliorates

protein:increased expression:pancreas (human)

NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756

G

vascular endothelial growth factor C

exacerbates

protein:increased expression:pancreas (human)

NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559

pancreatic adenosquamous carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

transforming growth factor beta 2

ameliorates

human cells in a mouse model

NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007

pancreatic ductal adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

anterior gradient 2, protein disulphide isomerase family member

protein:increased expression:pancreas

NCBI chrNW_004936546:3,316,622...3,328,317
Ensembl chrNW_004936546:3,315,543...3,328,369

G

calreticulin

ameliorates

human cells in mouse model
human cells in a mouse model

PMID:29072694 PMID:33028359

RGD:150520160 RGD:150521706

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

cyclin D1

severity

DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)

PMID:22939953 PMID:25470788

RGD:13462050 RGD:13462062

Ensembl chrNW_004936599:973,838...983,316

G

CD59 molecule (CD59 blood group)

disease_progression

protein:increased expression:blood (human)

NCBI chrNW_004936533:4,242,589...4,263,136

G

cyclin dependent kinase 4

severity

protein:increased expression:pancreas, islet of Langerhans (human)

NCBI chrNW_004936646:1,886,262...1,889,260

G

E2F transcription factor 1

severity

DNA:amplification: : (human)
protein:increased expression:pancreatic ductal cell, nucleus (human)

PMID:12650514 PMID:17233815 PMID:27573434

RGD:13838735 RGD:13838738 RGD:13838739

NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026

G

forkhead box M1

disease_progression

NCBI chrNW_004936606:3,185,289...3,198,427
Ensembl chrNW_004936606:3,185,982...3,198,378

G

far upstream element binding protein 1

mRNA:increased expression:pancreatic duct (human)

NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942

G

GLI pathogenesis related 2

disease_progression

protein:decreased expression:blood (human)

NCBI chrNW_004936524:4,118,964...4,139,901
Ensembl chrNW_004936524:4,118,697...4,139,942

G

glutamic-oxaloacetic transaminase 1

treatment

human cells in a mouse model

NCBI chrNW_004936636:617,376...640,424
Ensembl chrNW_004936636:617,356...640,932

G

heat shock protein family A (Hsp70) member 8

disease_progression

protein:decreased expression:blood (human)

NCBI chrNW_004936542:7,577,192...7,581,598
Ensembl chrNW_004936542:7,577,149...7,581,923

G

inhibitor of nuclear factor kappa B kinase subunit beta

susceptibility

NCBI chrNW_004936785:358,128...406,751
Ensembl chrNW_004936785:356,168...406,773

G

Janus kinase 1

mRNA:decreased expression:pancreatic ductal cell (human)

NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132

G

aflatoxin B1 aldehyde reductase member 2

protein:increased expression:pancreas

NCBI chrNW_004936474:5,565,715...5,573,048

G

mitogen-activated protein kinase 8

severity
disease_progression

protein:increased phosphorylation:pancreas (mouse)

PMID:23237571 PMID:28837246

RGD:14348974 RGD:14348975

NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907

G

placental growth factor

severity

associated with obesity

NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

mRNA, protein:increased expression:pancreas (human)

NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258

G

phosphoinositide-3-kinase regulatory subunit 2

severity

human cells in a mouse model

NCBI chrNW_004936596:3,010,526...3,021,848
Ensembl chrNW_004936596:3,010,488...3,021,920

G

phospholipase D1

severity

protein:increased expression:pancreas (human)

NCBI chrNW_004936593:844,634...1,049,478
Ensembl chrNW_004936593:930,637...1,046,821

G

protein tyrosine phosphatase receptor type B

disease_progression

protein:decreased expression:blood (human)

NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715

G

protein tyrosine phosphatase receptor type M

disease_progression

protein:decreased expression:blood (human)

NCBI chrNW_004936670:890,316...1,692,033
Ensembl chrNW_004936670:890,310...1,692,041

G

Rac family small GTPase 1

mRNA, protein:increased expression:pancreas (mouse)
mRNA:increased expression:pancreas (human)

PMID:21684285 PMID:23334332

RGD:14392806 RGD:14392816

NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676

G

RAS like proto-oncogene A

mRNA:increased expression:pancreas (human)

NCBI chrNW_004936478:15,167,651...15,186,594
Ensembl chrNW_004936478:15,167,751...15,186,633

G

S100 calcium binding protein A8

disease_progression

protein:increased expression:blood (human)

NCBI chrNW_004936580:3,256,399...3,256,913
Ensembl chrNW_004936580:3,256,417...3,256,913

G

SMAD family member 2

severity

NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697

G

transforming growth factor beta 1

ameliorates

protein:decreased expression:pancreas (human)

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

transforming growth factor beta 2

ameliorates

protein:decreased expression:pancreas (human)

NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007

G

transforming growth factor beta 3

ameliorates

protein:decreased expression:pancreas (human)

NCBI chrNW_004936488:4,986,712...5,008,728
Ensembl chrNW_004936488:4,986,748...5,008,496

G

transforming growth factor beta receptor 1

ameliorates

human cell line in a mouse model

NCBI chrNW_004936524:7,656,523...7,680,043
Ensembl chrNW_004936524:7,655,847...7,681,097

G

vascular endothelial growth factor D

protein:increased expression:blood serum (human)

NCBI chrNW_004936470:4,761,827...4,794,751
Ensembl chrNW_004936470:4,762,332...4,793,938

G

vanin 1

disease_progression

protein:increased expression:blood (human)

NCBI chrNW_004936560:701,857...729,516
Ensembl chrNW_004936560:701,892...729,526

pancreatic ductal carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin converting enzyme 2

protein:decreased expression:pancreas

NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702

G

ADAM metallopeptidase domain 8

disease_progression

mRNA:increased expression:pancreas

NCBI chrNW_004936486:19,389,925...19,403,577
Ensembl chrNW_004936486:19,391,324...19,402,332

G

ADAM metallopeptidase domain 9

disease_progression

protein:altered localization:cytoplasm

NCBI chrNW_004936710:2,301,470...2,388,533
Ensembl chrNW_004936710:2,301,730...2,387,695

G

anterior gradient 2, protein disulphide isomerase family member

mRNA:increased expression:pancreas

NCBI chrNW_004936546:3,316,622...3,328,317
Ensembl chrNW_004936546:3,315,543...3,328,369

G

angiotensin II receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936519:6,831,096...6,873,977
Ensembl chrNW_004936519:6,831,096...6,873,985

G

annexin A2

disease_progression

mRNA, protein:increased expression, altered localization:pancreas, plasma membrane

PMID:16450333 PMID:19260470

RGD:2317307 RGD:2325731

NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503

G

annexin A5

protein:increased expression:pancreas

NCBI chrNW_004936662:926,302...959,964
Ensembl chrNW_004936662:925,940...939,451

G

apolipoprotein C1

NCBI chrNW_004936706:1,519,248...1,520,102

G

arginase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:11,004,296...11,045,467
Ensembl chrNW_004936495:11,004,176...11,045,472

G

BMI1 proto-oncogene, polycomb ring finger

protein:increased expression:pancreas
protein:increased expression:exocrine pancreas:

NCBI chrNW_004936520:5,707,542...5,716,966
Ensembl chrNW_004936520:5,707,778...5,717,024

G

calreticulin

protein:increased expression:pancreatic duct

NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430

G

chromobox 7

disease_progression

protein:decreased expression:pancreas

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

cholecystokinin A receptor

mRNA:increased expression:pancreatic duct
protein:decreased expression:pancreas

PMID:9239407 PMID:12851875

RGD:4110816 RGD:4110818

NCBI chrNW_004936477:3,306,898...3,314,659
Ensembl chrNW_004936477:3,306,874...3,314,714

G

cholecystokinin B receptor

protein:decreased expression:pancreas

NCBI chrNW_004936842:329,551...341,491
Ensembl chrNW_004936842:329,376...341,808

G

cyclin D1

severity

protein:increased expression:pancreas (human)

Ensembl chrNW_004936599:973,838...983,316

G

CD40 molecule

treatment

protein:increased expression:dendritic cell

PMID:20976171 PMID:21436454 PMID:23983255

RGD:11522743 RGD:5490301 RGD:5490524

NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280

G

cyclin dependent kinase 6

treatment

human cells in a mouse model

NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516

G

cyclin dependent kinase inhibitor 1A

disease_progression

NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182

G

claudin 4

NCBI chrNW_004936543:2,984,797...2,986,563
Ensembl chrNW_004936543:2,984,996...2,985,625

G

chromosome unknown C19orf33 homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936801:1,077,823...1,080,317
Ensembl chrNW_004936801:1,079,594...1,080,296

G

C-X-C motif chemokine ligand 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936676:72,383...73,697
Ensembl chrNW_004936676:71,667...73,738

G

DNA methyltransferase 1

disease_progression

protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism

PMID:19424621 PMID:29844410

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

DNA methyltransferase 3 beta

disease_progression

NCBI chrNW_004936485:19,547,836...19,570,716

G

deltex E3 ubiquitin ligase 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936581:3,433,760...3,467,863
Ensembl chrNW_004936581:3,437,489...3,467,869

G

epidermal growth factor

disease_progression

protein:increased expression: :

NCBI chrNW_004936563:1,058,803...1,181,393

G

Fas ligand

protein:increased expression:pancreas, liver

PMID:10547193 PMID:15375495

RGD:2317741 RGD:2317747

NCBI chrNW_004936481:14,789,547...14,795,780

G

fascin actin-bundling protein 1

disease_progression

protein:increased expression:pancreas

NCBI chrNW_004936765:609,894...619,417
Ensembl chrNW_004936765:609,861...619,456

G

glycoprotein nmb

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936478:397,200...425,663
Ensembl chrNW_004936478:397,145...424,801

G

glutathione S-transferase pi 1

resistance

mRNA, protein:increased expression:pancreas
DNA:methylation: :

PMID:12488200 PMID:16537562 PMID:17265526

RGD:2317806 RGD:2317809 RGD:2317811

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

histone deacetylase 1

disease_progression

protein:increased expression:pancreas

NCBI chrNW_004936474:15,320,635...15,351,418
Ensembl chrNW_004936474:15,320,729...15,350,860

G

HEAT repeat containing 1

treatment

NCBI chrNW_004936484:16,310,766...16,355,977
Ensembl chrNW_004936484:16,312,223...16,357,099

G

hes family bHLH transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936711:640,002...642,580
Ensembl chrNW_004936711:639,905...642,622

G

hes related family bHLH transcription factor with YRPW motif 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936871:666,961...670,910
Ensembl chrNW_004936871:666,938...670,916

G

hes related family bHLH transcription factor with YRPW motif 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936639:3,705,225...3,714,696
Ensembl chrNW_004936639:3,703,447...3,716,820

G

insulin like growth factor 1

NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351

G

insulin like growth factor 1 receptor

protein:increased expression:pancreas

PMID:14506643 PMID:14627343

RGD:2317649 RGD:2317652

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

interleukin 4 receptor

protein:increased expression:pancreas

NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818

G

insulin

Glucagon/insulin

NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357

G

jagged canonical Notch ligand 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936485:8,857,688...8,894,270
Ensembl chrNW_004936485:8,857,669...8,895,315

G

jagged canonical Notch ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936621:363,489...380,616
Ensembl chrNW_004936621:366,616...380,618

G

lysine demethylase 2B

severity

mRNA, protein:increased expression:pancreas (human)

NCBI chrNW_004936558:2,771,420...2,897,694
Ensembl chrNW_004936558:2,771,420...2,897,292

G

KIT ligand

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936507:5,566,144...5,650,412
Ensembl chrNW_004936507:5,565,821...5,650,828

G

KRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

PMID:25347530 PMID:30654191

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

keratin 7

disease_progression

NCBI chrNW_004936512:9,641,587...9,656,573
Ensembl chrNW_004936512:9,641,587...9,656,524

G

L1 cell adhesion molecule

severity

protein:increased expression:pancreas (human)

NCBI chrNW_004936809:736,385...768,822
Ensembl chrNW_004936809:736,319...761,973

G

heat shock 70 kDa protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936727:1,718,952...1,721,691

G

heat shock 70 kDa protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936727:1,732,323...1,735,128

G

mucin-3B

disease_progression

mRNA:increased expression:pancreas

NCBI chrNW_004936543:886,333...904,504

G

angiotensin-converting enzyme

mRNA, protein:increased expression:pancreas

NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177

G

E3 ubiquitin-protein ligase DTX1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936668:3,006,539...3,021,066

G

mitogen-activated protein kinase kinase kinase 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936510:1,772,971...1,836,075
Ensembl chrNW_004936510:1,772,971...1,837,765

G

mitogen-activated protein kinase 3

treatment

human cells in mouse model

NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180

G

minichromosome maintenance complex component 7

mRNA, protein:increased expression:pancreatic duct

NCBI chrNW_004936543:238,573...246,746
Ensembl chrNW_004936543:233,960...246,746

G

MDM2 proto-oncogene

onset
severity

DNA:snp:promoter, intron:IVS1+309T>G (human)
protein:increased expression:pancreas (human)

PMID:15810085 PMID:19752772

RGD:2317414 RGD:2317416

NCBI chrNW_004936545:6,709,903...6,732,334

G

menin 1

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

MET proto-oncogene, receptor tyrosine kinase

protein:increased expression:pancreatic duct (human)

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

O-6-methylguanine-DNA methyltransferase

susceptibility

protein:increased activity, increased expression:ductal adenocarcinoma (human)
DNA:missense mutation:cds:p.L84F rs12917 (human)

PMID:9393761 PMID:16844323

RGD:2317648 RGD:2317664

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

matrix metallopeptidase 2

severity

protein:increased expression:pancreas

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

protein:increased expression:pancreas, serum
protein:increased expression:blood

PMID:18706098 PMID:20332475

RGD:2325830 RGD:2325844

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

mucin 1, cell surface associated

disease_progression

protein:increased expression, altered localization:pancreas

PMID:14681945 PMID:18713982 PMID:19109152

RGD:2317983 RGD:2324616 RGD:2324633

NCBI chrNW_004936580:4,691,870...4,694,092

G

mucin 4, cell surface associated

disease_progression

mRNA:increased expression:pancreas
protein:increased expression:pancreas

PMID:12657964 PMID:16049287

RGD:2324942 RGD:2324946

NCBI chrNW_004936784:515,608...539,915

G

mucin 5AC, oligomeric mucus/gel-forming

disease_progression

mRNA:increased expression:pancreas

PMID:7657125 PMID:10227724

RGD:2324907 RGD:2324986

NCBI chrNW_004936816:129,926...159,396

G

mucin 5B, oligomeric mucus/gel-forming

mRNA:increased expression:pancreas

NCBI chrNW_004936816:174,943...209,241

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:16,051,291...16,102,563
Ensembl chrNW_004936470:16,051,015...16,102,585

G

NFE2 like bZIP transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262

G

nitric oxide synthase 2

NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051

G

notch receptor 1

CTD Direct Evidence: marker/mechanism

PMID:19028876 PMID:19208345 PMID:20484026

RGD:2325323 RGD:2325324

NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428

G

notch receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429

G

notch receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936727:1,386,842...1,409,823

G

neurotrophic receptor tyrosine kinase 3

disease_progression

protein:increased expression:pancreas

PMID:10209957 PMID:11295066

RGD:2325660 RGD:2325663

NCBI chrNW_004936483:13,912,904...14,291,881
Ensembl chrNW_004936483:13,909,109...14,291,887

G

oncostatin M

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936904:390,089...394,195

G

palladin, cytoskeletal associated protein

protein:increased expression, alternative form:pancreas, fibroblast

NCBI chrNW_004936516:786,358...1,151,910
Ensembl chrNW_004936516:802,484...1,151,801

G

paired box 6

protein:increased expression:pancreatic duct (human)

NCBI chrNW_004936533:5,952,529...5,980,889
Ensembl chrNW_004936533:5,957,971...5,982,075

G

PMS1 homolog 1, mismatch repair system component

protein:increased expression:pancreatic duct

NCBI chrNW_004936506:8,118,816...8,197,040
Ensembl chrNW_004936506:8,119,494...8,197,768

G

peroxisome proliferator activated receptor gamma

disease_progression

NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743

G

prostaglandin-endoperoxide synthase 2

NCBI chrNW_004936481:3,821,564...3,828,086

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813

G

ring finger protein 2

protein:increased expression:pancreas

NCBI chrNW_004936481:5,070,578...5,110,087
Ensembl chrNW_004936481:5,070,578...5,110,068

G

retinoid X receptor alpha

severity

NCBI chrNW_004936669:2,735,111...2,763,060
Ensembl chrNW_004936669:2,738,448...2,763,070

G

solute carrier family 2 member 2

protein:increased expression:pancreatic duct

NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947

G

SMAD family member 4

disease_progression

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

smoothened, frizzled class receptor

NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281

G

serine/threonine kinase 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:579,816...601,033
Ensembl chrNW_004936588:579,816...603,654

G

transforming growth factor beta 1

disease_progression

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

transforming growth factor beta receptor 2

disease_progression

mRNA:increased expresssion:pancreas

PMID:10547197 PMID:17114585

RGD:2317498 RGD:2317500

NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430

G

thrombospondin 1

disease_progression

DNA:hypermethylation:promoter (human)

PMID:12429967 PMID:19065635

RGD:2325022 RGD:2325025

NCBI chrNW_004936471:3,064,466...3,081,125
Ensembl chrNW_004936471:3,064,422...3,081,949

G

transmembrane serine protease 3

NCBI chrNW_004936500:1,480,688...1,501,735
Ensembl chrNW_004936500:1,480,688...1,501,735

G

tumor protein p53

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

TSC complex subunit 2

severity

NCBI chrNW_004936694:1,958,152...1,993,373
Ensembl chrNW_004936694:1,958,154...1,993,363

G

thymidine phosphorylase

disease_progression

NCBI chrNW_004936629:315,609...320,356
Ensembl chrNW_004936629:315,610...319,076

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

von Hippel-Lindau tumor suppressor

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936602:3,135,790...3,140,622

G

YEATS domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:6,004,427...6,075,414
Ensembl chrNW_004936578:6,006,018...6,075,449

G

zinc finger ZZ-type containing 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936571:4,391,318...4,525,720
Ensembl chrNW_004936571:4,423,662...4,524,926

pancreatic endocrine carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas

PMID:15145354 PMID:22762150 PMID:25741868 PMID:29446198

NCBI chrNW_004936472:26,945,659...27,017,693

G

cut like homeobox 1

exacerbates

protein:increased expression:pancreas (human)

NCBI chrNW_004936543:1,482,606...1,781,294
Ensembl chrNW_004936543:1,485,970...1,796,070

G

death domain associated protein

disease_progression

DNA:frameshift, frameshift mutations, nonsense mutation, missense mutations:CDS:multiple (human)

NCBI chrNW_004936476:25,546,091...25,550,390
Ensembl chrNW_004936476:25,546,036...25,550,392

G

O-6-methylguanine-DNA methyltransferase

DNA:hypermethylation:promoter (human)

NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas

PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More...

NCBI chrNW_004936501:8,246,927...8,273,258

G

placental growth factor

treatment
disease_progression

human cells in a mouse model
protein:increased expression:serum (human)

PMID:23463017 PMID:26861455

RGD:14349029 RGD:14349030

NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142

papillary renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

baculoviral IAP repeat containing 3

exacerbates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

disease_progression

mRNA:increased expression:kidney (human)

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1

PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More...

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083

G

MET proto-oncogene, receptor tyrosine kinase

ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1

PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More...

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

proline rich mitotic checkpoint control factor

NCBI chrNW_004936580:5,927,575...5,954,636
Ensembl chrNW_004936580:5,927,847...5,953,796

G

von Hippel-Lindau tumor suppressor

ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1

PMID:7660122 PMID:7728151 PMID:7784063 PMID:7987306 PMID:7987327 More...

NCBI chrNW_004936602:3,135,790...3,140,622

G

X-linked inhibitor of apoptosis

exacerbates

mRNA:increased expression:kidney (human)

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

papillary thyroid carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATM serine/threonine kinase

susceptibility

associated with Radiation-Induced Neoplasms;DNA:SNPs,haplotypes:exon 39,intron 22,intron 48: p.D1853N, IVS22-77 T>C, IVS48 + 238 C>G (rs1801516, rs664677, rs609429)
ClinVar Annotator: match by term: Papillary thyroid carcinoma

PMID:19286843 PMID:19404735 PMID:20305132 PMID:23555315 PMID:25085752 More...

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

brain enriched guanylate kinase associated

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936604:4,162,728...4,195,540
Ensembl chrNW_004936604:4,162,658...4,195,815

G

B-Raf proto-oncogene, serine/threonine kinase

onset

DNA:mutation:cds:p.V600E(human)
ClinVar Annotator: match by term: Papillary thyroid carcinoma

PMID:12068308 PMID:12198537 PMID:12447372 PMID:12619120 PMID:12644542 More...

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

bromodomain containing 4

mRNA, protein:increased expression:thyroid

NCBI chrNW_004936596:5,176,682...5,246,102
Ensembl chrNW_004936596:5,177,147...5,246,518

G

calcium/calmodulin dependent protein kinase II inhibitor 1

mRNA:increased expression:thyroid gland

NCBI chrNW_004936474:6,463,691...6,466,641
Ensembl chrNW_004936474:6,461,050...6,466,641

G

catalase

protein:increased activity:plasma:

NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422

G

chromobox 7

mRNA,protein,DNA:decreased expression, loss of heterozygosity:thyroid gland:
mRNA:decreased expression:thyroid gland (mouse)

NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682

G

coiled-coil domain containing 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936614:3,093,083...3,206,147
Ensembl chrNW_004936614:3,092,882...3,394,303

G

cyclin D1

mRNA:increased expression:thyroid

Ensembl chrNW_004936599:973,838...983,316

G

cadherin 1

DNA:hypermethylation:promoter

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

catenin beta 1

disease_progression

mRNA:increased expression:thyroid

PMID:28677753 PMID:29498921

RGD:13792558 RGD:13792605

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Papillary thyroid carcinoma

PMID:19404735 PMID:20305132 PMID:23555315 PMID:25085752 PMID:25186627 More...

NCBI chrNW_004936551:305,617...343,369
Ensembl chrNW_004936551:305,611...351,063

G

iodothyronine deiodinase 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936604:5,241,877...5,243,910

G

dynein cytoplasmic 1 heavy chain 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936835:225,879...290,160
Ensembl chrNW_004936835:225,324...289,954

G

lysine methyltransferase 2D

associated with familial adenomatous polyposis;DNA:missense mutations, nonsense mutation

NCBI chrNW_004936512:6,819,240...6,860,852
Ensembl chrNW_004936512:6,822,057...6,854,451

G

lymphoid enhancer binding factor 1

mRNA:increased expression:thyroid

NCBI chrNW_004936818:453,635...569,194
Ensembl chrNW_004936818:453,635...567,469

G

DNA ligase 4

ClinVar Annotator: match by term: Papillary thyroid carcinoma

NCBI chrNW_004936472:3,861,833...3,867,943
Ensembl chrNW_004936472:3,861,866...3,867,933

G

MYC proto-oncogene, bHLH transcription factor

mRNA:increased expression:thyroid

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

NK2 homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Papillary thyroid carcinoma

PMID:25741868 PMID:28492532

NCBI chrNW_004936501:8,246,927...8,273,258

G

plasminogen activator, urokinase

severity

mRNA:increased expression:thyroid gland (human)

NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877

G

protein phosphatase 2 regulatory subunit B'gamma

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936835:54,478...192,486
Ensembl chrNW_004936835:96,930...192,756

G

RAP1 GTPase activating protein

protein:decreased expression:thyroid gland (human)

NCBI chrNW_004936474:7,242,528...7,284,342
Ensembl chrNW_004936474:7,242,824...7,284,395

G

ret proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602

G

RUNX family transcription factor 3

DNA:hypermethylation:promoter

NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910

G

retinoid X receptor gamma

mRNA:increased expression:thyroid

NCBI chrNW_004936481:19,789,753...19,826,665
Ensembl chrNW_004936481:19,789,641...19,826,698

G

snail family transcriptional repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987

G

snail family transcriptional repressor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642

G

tumor protein p53

susceptibility

associated with Radiation-Induced Neoplasms;DNA:SNPs, haplotypes:exon 4: p.R72P (rs1042522) (human)

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tropomyosin 3

mRNA:increased expression:thyroid

NCBI chrNW_004936580:3,860,185...3,893,251
Ensembl chrNW_004936580:3,860,190...3,889,978

G

tryptophanyl-tRNA synthetase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936604:3,985,002...4,016,870
Ensembl chrNW_004936604:3,984,872...4,016,911

G

WD repeat domain 20

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936835:355,300...428,723
Ensembl chrNW_004936835:355,288...428,725

G

WD repeat domain 3

susceptibility

DNA:snps, haplotype:introns: c.500+239G>A, c.*1-2382A>C (rs3765501, rs4658973) (human)

NCBI chrNW_004936627:2,972,939...2,999,052
Ensembl chrNW_004936627:2,972,959...3,000,356

G

X-ray repair cross complementing 1

susceptibility

DNA:SNP:exon 10: p.R399Q (rs25487) (Human)

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

zinc finger E-box binding homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936574:17,643...175,762
Ensembl chrNW_004936574:17,684...178,293

G

zinc finger E-box binding homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:32,240,730...32,372,413
Ensembl chrNW_004936469:32,240,835...32,371,267

Pediatric Adrenocortical Carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tumor protein p53

ClinVar Annotator: match by term: ADRENOCORTICAL CARCINOMA, PEDIATRIC

PMID:9582268 PMID:9704930 PMID:9704931 PMID:10864200 PMID:11481490 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

placental site trophoblastic tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glypican 3

protein:increased expression:placenta, trophoblast cells (human)

NCBI chrNW_004936691:1,060,013...1,459,736
Ensembl chrNW_004936691:1,059,994...1,459,740

prostate adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

susceptibility

DNA:SNPs, haplotypes:5' utr, introns, exon:multiple

NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928

G

adiponectin receptor 1

susceptibility

DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human)

NCBI chrNW_004936567:1,658,405...1,674,794
Ensembl chrNW_004936567:1,658,383...1,676,199

G

AKT serine/threonine kinase 1

treatment

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

AKT serine/threonine kinase 2

treatment

NCBI chrNW_004936661:2,652,568...2,694,039
Ensembl chrNW_004936661:2,652,566...2,694,086

G

AKT serine/threonine kinase 3

treatment

NCBI chrNW_004936526:6,944,056...7,201,226
Ensembl chrNW_004936526:6,944,005...7,200,583

G

androgen receptor

treatment

NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932

G

bridging integrator 1

NCBI chrNW_004936469:44,128,308...44,185,739
Ensembl chrNW_004936469:44,127,970...44,185,246

G

baculoviral IAP repeat containing 6

ameliorates

mRNA:increased expression:prostate gland (human)

NCBI chrNW_004936493:903,295...1,115,434
Ensembl chrNW_004936493:899,961...1,115,493

G

baculoviral IAP repeat containing 7

exacerbates

mRNALincreased expression:prostate gland (human)

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

B-Raf proto-oncogene, serine/threonine kinase

NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664

G

calcium/calmodulin dependent protein kinase II inhibitor 1

treatment

NCBI chrNW_004936474:6,463,691...6,466,641
Ensembl chrNW_004936474:6,461,050...6,466,641

G

cyclin B1

severity

NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704

G

cyclin E2

NCBI chrNW_004936544:7,839,730...7,852,251
Ensembl chrNW_004936544:7,839,113...7,851,335

G

CD9 molecule

disease_progression

DNA, mRNA:deletion, point mutation, decreased expression:prostate gland

NCBI chrNW_004936709:1,497,504...1,530,114

G

chromodomain helicase DNA binding protein 4

mRNA:decreased expression:prostate gland (human)

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

component of inhibitor of nuclear factor kappa B kinase complex

treatment

NCBI chrNW_004936636:33,933...78,990
Ensembl chrNW_004936636:33,673...79,194

G

clusterin

treatment

NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836

G

cAMP responsive element binding protein 3 like 4

PMID:11830526 PMID:17270658

RGD:13504714 RGD:13504715

NCBI chrNW_004936580:3,715,122...3,720,154
Ensembl chrNW_004936580:3,715,027...3,724,282

G

catenin beta 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:10192393 PMID:25741868 PMID:26619011

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

DNA methyltransferase 1

mRNA,protein:increased expression:prostate gland:

NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416

G

DNA methyltransferase 3 alpha

mRNA:increased expression:prostate gland:

NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610

G

DNA methyltransferase 3 beta

mRNA,protein:increased expression:prostate gland:

NCBI chrNW_004936485:19,547,836...19,570,716

G

fibroblast growth factor receptor 1

PMID:18068632 PMID:23576558

RGD:13504748 RGD:2298702

NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508

G

growth factor receptor bound protein 2

NCBI chrNW_004936594:592,760...661,369
Ensembl chrNW_004936594:592,740...661,369

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of prostate
ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363

G

insulin like growth factor 1 receptor

treatment
disease_progression

PMID:8692980 PMID:25442907 PMID:25862373 PMID:26452103

RGD:13504753 RGD:13504767 RGD:13504768 RGD:13504771

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

inhibitor of nuclear factor kappa B kinase subunit beta

treatment

NCBI chrNW_004936785:358,128...406,751
Ensembl chrNW_004936785:356,168...406,773

G

integrin linked kinase

disease_progression

protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004)

NCBI chrNW_004936842:661,961...667,993
Ensembl chrNW_004936842:661,996...667,993

G

insulin receptor

treatment

NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

protein:increased expression, increased activation:significantly higher levels in invading vs organ-confined specimens (P<0.001)

NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350

G

kinase insert domain receptor

protein:increased expression:prostate gland
protein:increased expression:tumor:relative to benign prostatic hypertrophy (BPH) tissue

PMID:17491265 PMID:20808233

RGD:2291925 RGD:5684541

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

mitogen-activated protein kinase kinase 1

disease_progression

metastasis; inhibition reduced invasiveness of prostate tumor cells

NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302

G

mitogen-activated protein kinase 1

treatment

PMID:22139534 PMID:28492138

RGD:13504818 RGD:13504820

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

MYC proto-oncogene, bHLH transcription factor

human gene in mouse model

PMID:14522256 PMID:20195545

RGD:7207413 RGD:7207781

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

nuclear receptor coactivator 2

ameliorates

human cells in mouse model

NCBI chrNW_004936496:14,844,923...15,102,922
Ensembl chrNW_004936496:14,844,855...15,016,454

G

NFKB inhibitor alpha

severity

protein:increased serine phosphorylation

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612

G

peptidylglycine alpha-amidating monooxygenase

mRNA:increased expression:prostate gland (human)

NCBI chrNW_004936523:1,492,795...1,786,942
Ensembl chrNW_004936523:1,493,450...1,750,524

G

platelet derived growth factor subunit A

protein:increased expression:prostate

NCBI chrNW_004936754:808,894...828,554
Ensembl chrNW_004936754:808,213...828,613

G

platelet derived growth factor receptor alpha

protein:increased expression:prostate

NCBI chrNW_004936482:16,804,129...16,853,539
Ensembl chrNW_004936482:16,807,569...16,853,587

G

3-phosphoinositide dependent protein kinase 1

treatment

NCBI chrNW_004936694:1,444,819...1,487,628
Ensembl chrNW_004936694:1,444,880...1,488,265
Ensembl chrNW_004936694:1,444,880...1,488,265

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:18676830 More...

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

NCBI chrNW_004936540:907,118...1,041,814
Ensembl chrNW_004936540:907,112...1,041,848

G

protein kinase C theta

mRNA:increased expression:prostate

NCBI chrNW_004936484:8,048,239...8,166,058
Ensembl chrNW_004936484:8,048,132...8,167,636

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096

G

RELA proto-oncogene, NF-kB subunit

disease_progression

protein:increased expression:prostate gland

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813

G

signal transducer and activator of transcription 1

disease_progression

protein:increased activity:prostate

NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756

G

telomerase reverse transcriptase

treatment

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

transmembrane serine protease 2

disease_progression

protein:increased expression, altered localization:prostate gland

NCBI chrNW_004936500:2,199,877...2,222,174
Ensembl chrNW_004936500:2,199,835...2,222,174

G

tumor protein p53

ClinVar Annotator: match by term: Adenocarcinoma of prostate
ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1565143 PMID:1565144 PMID:11370630 PMID:12826609 PMID:19468865 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

rectum adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Rectum adenocarcinoma

PMID:24033266 PMID:25741868 PMID:26467025 PMID:26530882 PMID:28195569 More...

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

baculoviral IAP repeat containing 2

disease_progression

mRNA:increased expression:rectum (human)

NCBI chrNW_004936551:5,515,904...5,535,864

G

baculoviral IAP repeat containing 3

ameliorates

mRNA:increased expression:rectum (human)

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

chromodomain helicase DNA binding protein 4

mRNA:increased expression:rectum (human)

NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149

G

eukaryotic translation elongation factor 2

protein:increased expression:rectum (human)

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

lysine demethylase 6A

exacerbates

mRNA:decreased expression:rectum (human)

NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163

G

solute carrier family 7 member 5

treatment

NCBI chrNW_004936641:1,513,110...1,538,955

G

signal transducer and activator of transcription 3

DNA:missense mutation:CDS: (rs2293152) (human)

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

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signal transducer and activator of transcription 4

DNA:SNP:intron: (rs3024861) (human)

NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689

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signal transducer and activator of transcription 6

DNA:SNP:intron: (rs3024979) (human)

NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157

renal cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1

disease_progression

DNA:polymorphism: :3435C>T (human)

PMID:12089380 PMID:17177989

RGD:2315557 RGD:2315559

NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427

G

acetylcholinesterase (Cartwright blood group)

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:856,678...862,080
Ensembl chrNW_004936543:856,676...862,109

G

adiponectin, C1Q and collagen domain containing

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928

G

alpha fetoprotein

NCBI chrNW_004936598:2,058,474...2,077,711
Ensembl chrNW_004936598:2,058,117...2,077,728

G

angiotensin II receptor type 1

severity

protein:increased expression:kidney

NCBI chrNW_004936519:6,831,096...6,873,977
Ensembl chrNW_004936519:6,831,096...6,873,985

G

angiotensin II receptor type 2

disease_progression

protein:increased expression:kidney

NCBI chrNW_004936479:13,252,678...13,255,570
Ensembl chrNW_004936479:13,252,678...13,255,570

G

AHNAK nucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936581:702,579...792,762

G

A-kinase anchoring protein 13

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936483:11,661,862...11,977,292

G

AKT serine/threonine kinase 1

protein:increased serine phosphorylation:kidney

NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093

G

AKT serine/threonine kinase 3

susceptibility

DNA:missense mutation:exon, intron:multiple

NCBI chrNW_004936526:6,944,056...7,201,226
Ensembl chrNW_004936526:6,944,005...7,200,583

G

aminolevulinate dehydratase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936559:226,481...237,258
Ensembl chrNW_004936559:226,424...241,684

G

aldehyde dehydrogenase 1 family member A1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532

G

ALK receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874

G

arachidonate 12-lipoxygenase, 12R type

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985

G

arachidonate 5-lipoxygenase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931

G

alpha-methylacyl-CoA racemase

NCBI chrNW_004936518:7,072,436...7,088,927
Ensembl chrNW_004936518:7,072,403...7,088,929

G

angiogenin

protein:increased expression:serum

NCBI chrNW_004936880:39,372...40,070

G

angiopoietin 1

severity

mRNA:altered expression:kidney

NCBI chrNW_004936470:37,105,469...37,328,183
Ensembl chrNW_004936470:37,105,466...37,328,190

G

annexin A1

NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413

G

annexin A2

NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503

G

annexin A4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936491:13,982,926...14,047,690
Ensembl chrNW_004936491:13,982,677...14,047,690

G

adaptor related protein complex 5 subunit mu 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:1,862,790...1,900,955

G

apoptotic peptidase activating factor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:14,818,561...14,902,231
Ensembl chrNW_004936492:14,816,623...14,902,132

G

APC regulator of WNT signaling pathway

severity
disease_progression
onset

DNA:LOH: :
DNA,protein:LOH,decreased expression: :

PMID:10426194 PMID:15203750 PMID:16116480

RGD:7242056 RGD:7242059 RGD:7242060

NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453

G

adenine phosphoribosyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936641:913,674...916,312
Ensembl chrNW_004936641:913,475...918,748

G

aryl hydrocarbon receptor nuclear translocator

treatment

DNA:missense mutation: :pF446L (human)

NCBI chrNW_004936580:1,038,420...1,093,319
Ensembl chrNW_004936580:1,036,973...1,082,984

G

ankyrin repeat and SOCS box containing 15

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936605:1,852,109...1,884,517
Ensembl chrNW_004936605:1,852,059...1,884,546

G

ankyrin repeat, SAM and basic leucine zipper domain containing 1

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936589:1,756,616...1,799,810
Ensembl chrNW_004936589:1,756,616...1,799,580

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Renal adenocarcinoma

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

ATP synthase membrane subunit c locus 2

DNA:hypermethylation:promoter

NCBI chrNW_004936512:10,908,915...10,918,445
Ensembl chrNW_004936512:10,908,881...10,918,445

G

aurora kinase A

mRNA, protein:increased expression:kidney

NCBI chrNW_004936875:295,238...310,457

G

BCL2 associated agonist of cell death

NCBI chrNW_004936599:4,924,349...4,933,683
Ensembl chrNW_004936599:4,924,789...4,933,368

G

BCL2 antagonist/killer 1

severity

NCBI chrNW_004936476:25,347,608...25,354,772
Ensembl chrNW_004936476:25,347,545...25,355,789

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BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

PMID:22138691 PMID:22683710 PMID:23797736 PMID:25231345

NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806

G

butyrylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936707:1,784,338...1,913,401
Ensembl chrNW_004936707:1,854,444...1,913,460

G

BCL2 apoptosis regulator

disease_progression

PMID:17482919 PMID:18283311

RGD:2293019 RGD:2298896

NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921

G

BCL2 like 1

NCBI chrNW_004936485:18,654,046...18,707,324

G

BCL2 interacting killer

protein:decreased expression:kidney

G

baculoviral IAP repeat containing 2

disease_progression

mRNA:altered expression:kidney

NCBI chrNW_004936551:5,515,904...5,535,864

G

baculoviral IAP repeat containing 3

mRNA:altered expression:kidney

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

baculoviral IAP repeat containing 5

disease_progression

CTD Direct Evidence: therapeutic
mRNA:splice variant
protein:increased expression:kidney

PMID:12115583 PMID:16188142 PMID:17363528

RGD:2293102 RGD:2293108

NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636

G

baculoviral IAP repeat containing 7

CTD Direct Evidence: marker/mechanism

PMID:17437058 PMID:25401301

NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931

G

bone morphogenetic protein 4

severity

NCBI chrNW_004936697:1,054,237...1,061,468
Ensembl chrNW_004936697:1,056,636...1,061,468

G

bone morphogenetic protein 6

mRNA,protein:increased expression:kidney

NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023

G

bone morphogenetic protein 7

disease_progression

NCBI chrNW_004936530:71,965...143,940
Ensembl chrNW_004936530:71,920...143,940

G

basigin (Ok blood group)

disease_progression

protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism

PMID:17021824 PMID:36574092

NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287

G

BTG anti-proliferation factor 2

mRNA:decreased expression:kidney

NCBI chrNW_004936567:1,310,525...1,314,469
Ensembl chrNW_004936567:1,309,658...1,314,515

G

BTG anti-proliferation factor 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936505:10,032,333...10,046,008
Ensembl chrNW_004936505:10,032,237...10,046,047

G

carbonic anhydrase 9

disease_progression

protein:increased expression:serum, urine
DNA, mRNA:hypomethylation, increased expression:promoter, kidney

PMID:11506497 PMID:12883698 PMID:12966427 PMID:18464292

RGD:2293191 RGD:2293198 RGD:2293199 RGD:2293201

NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433

G

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chrNW_004936493:5,308,268...5,332,934
Ensembl chrNW_004936493:5,310,228...5,332,918

G

capping actin protein, gelsolin like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936712:1,793,666...1,803,621
Ensembl chrNW_004936712:1,793,480...1,806,602

G

capping actin protein of muscle Z-line subunit alpha 2

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936589:2,194,332...2,234,547
Ensembl chrNW_004936589:2,194,332...2,234,653

G

caspase recruitment domain family member 11

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936823:580,438...621,298
Ensembl chrNW_004936823:581,955...621,208

G

caspase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936527:739,325...754,259
Ensembl chrNW_004936527:739,281...754,331

G

caspase 3

NCBI chrNW_004936554:4,571,072...4,593,765

G

caveolin 1

disease_progression

protein:increased expression:kidney
ClinVar Annotator: match by term: Renal cell carcinoma

PMID:15247769 PMID:28492532

NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170

G

cyclin B1

disease_progression

protein:increased expression:kidney

NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704

G

cyclin D1

DNA:polymorphism

PMID:15538282 PMID:17924468

RGD:2289127 RGD:2289130

Ensembl chrNW_004936599:973,838...983,316

G

cyclin D3

disease_progression

NCBI chrNW_004936476:17,799,754...17,886,835
Ensembl chrNW_004936476:17,879,869...17,886,827

G

cyclin E1

mRNA, protein:increased expression:kidney

NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008

G

CD40 molecule

treatment

PMID:12594303 PMID:15282531 PMID:20426873

RGD:11522744 RGD:7248440 RGD:7248724

NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280

G

CD44 molecule (IN blood group)

severity
disease_progression

protein:increased expression:kidney

PMID:12833185 PMID:17284111

RGD:2289351 RGD:2289360

NCBI chrNW_004936533:2,949,026...3,033,166

G

CD46 molecule

protein:decreased expression:tumor:expression associated with presence of complement C3d on tumor cells (p<0.02) and with tumor stage (p<0.04)

NCBI chrNW_004936557:5,136,784...5,175,543

G

cell division cycle 14B

severity

mRNA:decreased expression:kidney:

NCBI chrNW_004936487:430,449...482,517
Ensembl chrNW_004936487:554,611...564,782

G

cadherin 1

disease_progression
onset

protein:decreased expression, altered localization:kidney, nucleus
DNA:LOH: :

PMID:15203750 PMID:17906660

RGD:2289489 RGD:7242059

NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203

G

cyclin dependent kinase 2

NCBI chrNW_004936646:379,849...385,648
Ensembl chrNW_004936646:379,842...385,877

G

cyclin dependent kinase 4

protein:increased expression:kidney

NCBI chrNW_004936646:1,886,262...1,889,260

G

cyclin dependent kinase inhibitor 1B

disease_progression

mRNA, protein:increased expression:kidney
protein:decreased expression:kidney

PMID:17924468 PMID:18425369 PMID:18495610

RGD:2289127 RGD:2293589 RGD:2293590

NCBI chrNW_004936587:4,573,166...4,578,480
Ensembl chrNW_004936587:4,572,728...4,578,461

G

cyclin dependent kinase inhibitor 2B

DNA:loss of heterozygosity, deletion

NCBI chrNW_004936652:3,576,975...3,582,790
Ensembl chrNW_004936652:3,538,986...3,581,159

G

CF transmembrane conductance regulator

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936589:1,565,933...1,719,208

G

calponin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:453,908...459,916
Ensembl chrNW_004936588:453,876...460,015

G

catechol-O-methyltransferase

susceptibility

DNA:polymorphism:exon

NCBI chrNW_004936619:3,847,059...3,883,866
Ensembl chrNW_004936619:3,876,299...3,882,747

G

carboxypeptidase Q

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:45,489,562...45,848,412
Ensembl chrNW_004936470:45,485,926...45,848,416

G

cellular retinoic acid binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936471:36,665,641...36,672,626
Ensembl chrNW_004936471:36,662,647...36,672,606

G

CASP2 and RIPK1 domain containing adaptor with death domain

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936507:10,077,345...10,264,705
Ensembl chrNW_004936507:10,098,171...10,264,716

G

C-reactive protein

disease_progression

NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606

G

crystallin alpha B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936612:2,532,851...2,536,473
Ensembl chrNW_004936612:2,532,812...2,537,495

G

colony stimulating factor 1 receptor

treatment

mouse cell line in a mouse model
mRNA:increased expression:kidney

PMID:18592004 PMID:22052465 PMID:32302573

RGD:150524293 RGD:2299092 RGD:7257566

NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923

G

CUB and Sushi multiple domains 3

CTD Direct Evidence: marker/mechanism

PMID:22138691 PMID:23797736

NCBI chrNW_004936470:32,244,712...33,323,374
Ensembl chrNW_004936470:32,245,093...33,324,814

G

cytotoxic T-lymphocyte associated protein 4

DNA:SNPs:exons:rs3087243, rs231775 (human)

NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643

G

catenin alpha 1

disease_progression

protein:decreased expression:kidney

NCBI chrNW_004936531:7,865,907...8,036,020
Ensembl chrNW_004936531:7,865,820...8,037,935

G

catenin beta 1

disease_progression

ClinVar Annotator: match by term: Renal adenocarcinoma
protein:increased expression:kidney

PMID:11831984 PMID:15330191 PMID:26822237

RGD:2289794 RGD:2289835

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

cathepsin D

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936816:680,798...690,959
Ensembl chrNW_004936816:680,798...691,039

G

cullin 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:16,886,416...16,901,532
Ensembl chrNW_004936476:16,887,610...16,901,458

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Renal adenocarcinoma

NCBI chrNW_004936551:305,617...343,369
Ensembl chrNW_004936551:305,611...351,063

G

death associated protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936680:2,842,930...3,020,757
Ensembl chrNW_004936680:2,842,547...3,021,058

G

delta like canonical Notch ligand 4

treatment

NCBI chrNW_004936471:4,320,235...4,330,251
Ensembl chrNW_004936471:4,320,933...4,330,253

G

dynein heavy chain domain 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936842:543,702...630,585

G

estrogen receptor binding site associated antigen 9

disease_progression

NCBI chrNW_004936470:35,449,920...35,473,635
Ensembl chrNW_004936470:35,450,292...35,473,110

G

eukaryotic translation elongation factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609

G

epidermal growth factor receptor

protein:increased expression:tumor

NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528

G

egl-9 family hypoxia inducible factor 1

protein:increased expression:kidney

NCBI chrNW_004936484:19,343,770...19,386,087

G

egl-9 family hypoxia inducible factor 2

protein:increased expression:kidney

NCBI chrNW_004936661:3,061,391...3,070,219
Ensembl chrNW_004936661:3,061,308...3,070,192

G

egl-9 family hypoxia inducible factor 3

protein:increased expression:serum

NCBI chrNW_004936494:8,240,272...8,267,487
Ensembl chrNW_004936494:8,238,858...8,267,606

G

elongin C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936648:2,606,075...2,629,997
Ensembl chrNW_004936648:2,604,283...2,630,035

G

endothelial PAS domain protein 1

CTD Direct Evidence: marker/mechanism

PMID:12750296 PMID:21131975

NCBI chrNW_004936508:5,855,748...5,938,879
Ensembl chrNW_004936508:5,855,732...5,938,856

G

erb-b2 receptor tyrosine kinase 2

mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism

PMID:10897039 PMID:15360049 PMID:17296437

RGD:2289930 RGD:2289987

NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956

G

erb-b2 receptor tyrosine kinase 4

mRNA, protein:decreased expression:kidney

NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035

G

fatty acid amide hydrolase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936980:183,629...319,072
Ensembl chrNW_004936980:183,629...260,764

G

Fas cell surface death receptor

protein:increased expression:serum
DNA:missense mutations:exon

PMID:10654915 PMID:11435457 PMID:12460460 PMID:17031406

RGD:2290099 RGD:2290131 RGD:2290132 RGD:2290133

NCBI chrNW_004936735:209,369...234,582

G

Fas ligand

PMID:11435457 PMID:17641033

RGD:2290051 RGD:2290132

NCBI chrNW_004936481:14,789,547...14,795,780

G

fibroblast growth factor receptor 1

disease_progression

NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508

G

fragile histidine triad diadenosine triphosphatase

DNA:translocation::t(3;8)(p14;q24.1) results in disruption of FHIT and TRC8/RNF139 genes
protein:decreased expression::reduced or negative expression in 78% of clear cell RCCs

PMID:10530564 PMID:17539022

RGD:2289870 RGD:2289903

NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506

G

folliculin

treatment

NCBI chrNW_004936741:881,150...901,296
Ensembl chrNW_004936741:880,736...901,468

G

fms related receptor tyrosine kinase 1

mRNA:increased expression:tumor:expression significantly higher in tumors than corresponding normal tissue (p=0.01), significantly correlated with VEGF expression
protein:increased expression:kidney, blood, myeloid cell
CTD Direct Evidence: therapeutic

PMID:11846206 PMID:16596207 PMID:18566400

RGD:2289960 RGD:2301250

NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041

G

formin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936526:9,832,790...10,169,488
Ensembl chrNW_004936526:9,833,128...10,169,267

G

fibronectin 1

severity

NCBI chrNW_004936586:1,708,803...1,773,372
Ensembl chrNW_004936586:1,708,684...1,773,383

G

fucose-1-phosphate guanylyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936571:1,522,765...1,530,418
Ensembl chrNW_004936571:1,522,741...1,530,725

G

fibroblast growth factor receptor substrate 2

disease_progression

NCBI chrNW_004936545:7,286,018...7,407,623
Ensembl chrNW_004936545:7,396,023...7,407,637

G

FTO alpha-ketoglutarate dependent dioxygenase

treatment

NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588

G

growth hormone releasing hormone

NCBI chrNW_004936561:3,946,256...3,954,472
Ensembl chrNW_004936561:3,950,340...3,952,405

G

gap junction protein beta 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936762:389,655...398,035
Ensembl chrNW_004936762:389,669...395,898

G

growth factor receptor bound protein 7

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337

G

glutathione-disulfide reductase

protein:decreased expression:kidney:

NCBI chrNW_004936792:531,076...579,083
Ensembl chrNW_004936792:531,756...579,166

G

glutathione S-transferase pi 1

protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism

PMID:15108329 PMID:20464042

NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050

G

histidyl-tRNA synthetase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:9,610,335...9,625,203
Ensembl chrNW_004936531:9,610,306...9,625,551

G

hepatitis A virus cellular receptor 1

disease_progression

NCBI chrNW_004936515:6,030,402...6,051,161

G

hepatitis A virus cellular receptor 2

susceptibility

DNA:polymorphisms: :-574G>T, +4259T>G (human)

NCBI chrNW_004936515:6,001,324...6,015,407

G

hypoxia inducible factor 1 subunit alpha

disease_progression

NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157

G

HNF1 homeobox A

NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505

G

HNF1 homeobox B

NCBI chrNW_004936490:649,551...702,448
Ensembl chrNW_004936490:649,546...702,672

G

homeobox B13

disease_progression

DNA:hypermethylation

NCBI chrNW_004936490:12,688,572...12,690,908
Ensembl chrNW_004936490:12,688,559...12,690,908

G

heat shock protein family A (Hsp70) member 9

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936531:7,702,186...7,716,428
Ensembl chrNW_004936531:7,702,695...7,716,380

G

heat shock protein family B (small) member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186

G

heat shock protein family D (Hsp60) member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936506:1,678,069...1,687,632

G

insulin like growth factor 1 receptor

NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925

G

insulin like growth factor binding protein 3

mRNA,protein:increased expression:tumor:27/43 (63%) by cDNA microarray, 43/58 (74%) by immunohistochemistry

NCBI chrNW_004936478:20,511,490...20,518,251
Ensembl chrNW_004936478:20,510,137...20,518,306

G

insulin like growth factor binding protein 7

mRNA:decreased expression:kidney

NCBI chrNW_004936482:19,119,339...19,186,679
Ensembl chrNW_004936482:19,118,321...19,186,685

G

interleukin 13

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373

G

interleukin 1 receptor antagonist

NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340

G

interleukin 2

NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625

G

interleukin 4 receptor

susceptibility
disease_progression

CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.I50V (human)

PMID:12171893 PMID:22317767 PMID:30472377

RGD:7207066 RGD:7207070

NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818

G

interleukin 6

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936549:7,015,595...7,016,246

G

interleukin 6 receptor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885

G

inositol polyphosphate-4-phosphatase type II B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936535:5,427,131...6,168,622
Ensembl chrNW_004936535:5,794,135...6,171,072

G

insulin receptor

mRNA:increased expression:tumor:isoform A

NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668

G

Jun proto-oncogene, AP-1 transcription factor subunit

protein:increased activation:tumor:associated with early carcinogenesis--10/18 (55.5%) of pT1a cases vs 11/44 (25%) of pT1b or greater cases

NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350

G

junction plakoglobin

DNA:increased methylation:promoter:significantly increased methylation vs normal kidney (p < 0.01)
protein:decreased expression:tumor:relative to normal kidney (p<0.001), higher expression associated with better survival rate (p<0.05)

PMID:9891472 PMID:15701841

RGD:2291866 RGD:2291890

NCBI chrNW_004936490:16,671,176...16,694,552
Ensembl chrNW_004936490:16,668,575...16,694,615

G

KN motif and ankyrin repeat domains 1

DNA, mRNA, protein:hypermethylation, decreased expression:kidney

NCBI chrNW_004936503:4,125,302...4,255,880
Ensembl chrNW_004936503:4,122,204...4,246,680

G

potassium voltage-gated channel subfamily H member 1

protein:increased expression:kidney (human)

NCBI chrNW_004936557:2,133,596...2,493,170
Ensembl chrNW_004936557:2,133,564...2,493,155

G

potassium calcium-activated channel subfamily M alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936521:2,000,113...2,706,010
Ensembl chrNW_004936521:2,000,109...2,705,365

G

lysine demethylase 4C

DNA:deletion:cds (human)

NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082

G

lysine demethylase 5C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966

G

lysine demethylase 6A

mRNA, protein:increased expression:kidney (human)

NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163

G

lysine demethylase 6B

mRNA, protein:increased expression:kidney (human)

NCBI chrNW_004936595:1,077,318...1,099,082
Ensembl chrNW_004936595:1,089,544...1,097,595

G

kinase insert domain receptor

treatment

PMID:16763608 PMID:17332933 PMID:17653245

RGD:126925190 RGD:2301756 RGD:8552363

NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002

G

kelch like ECH associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936659:785,059...793,775
Ensembl chrNW_004936659:782,340...793,688

G

KIT proto-oncogene, receptor tyrosine kinase

papillary RCC only; DNA:mutation:intron:heterozygous T>A mutation in intron 17 found in 94% of cases, also protein found to be cytoplasmic not membrane-bound in 100% of cases
chromophobe RCC only; mRNA:increased expression:tumor:positive in 6/7 chromophobe RCCs, but 0/15 clear cell RCCs and 1/15 papillary RCCs

PMID:15073597 PMID:15780567

RGD:2292414 RGD:2292421

NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274

G

kallikrein related peptidase 6

protein:decreased expression:kidney

NCBI chrNW_004936889:621,645...628,454
Ensembl chrNW_004936889:621,630...629,678

G

KRAS proto-oncogene, GTPase

mRNA:increased expression:kidney

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

keratin 32

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936490:16,382,244...16,388,812
Ensembl chrNW_004936490:16,382,244...16,388,812

G

keratin 7

CTD Direct Evidence: marker/mechanism

PMID:15108329 PMID:16927643

NCBI chrNW_004936512:9,641,587...9,656,573
Ensembl chrNW_004936512:9,641,587...9,656,524

G

keratin 8

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936512:10,247,049...10,254,748
Ensembl chrNW_004936512:10,246,991...10,254,827

G

L1 cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936809:736,385...768,822
Ensembl chrNW_004936809:736,319...761,973

G

lactate dehydrogenase B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936548:5,224,905...5,244,708
Ensembl chrNW_004936548:5,227,666...5,244,525

G

leptin

resistance

NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334

G

lectin, mannose binding 2 like

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936744:665,893...691,335
Ensembl chrNW_004936744:664,733...691,347

G

leucyl and cystinyl aminopeptidase

NCBI chrNW_004936523:6,443,571...6,533,122
Ensembl chrNW_004936523:6,445,939...6,532,566

G

aminoacylase-1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936529:3,308,863...3,333,877
Ensembl chrNW_004936529:3,327,879...3,333,879

G

adhesion G protein-coupled receptor B1

severity

NCBI chrNW_004936470:9,247,749...9,313,230
Ensembl chrNW_004936470:9,248,319...9,313,230

G

cytochrome P450 1A1

no_association

DNA:SNPs: :6235T>C, 4889A>G, 4887C>A (human)
DNA:polymorphism: :p.I462V (human)

PMID:9631944 PMID:11115552 PMID:22000673 PMID:22296350

RGD:7257729 RGD:7296937 RGD:7296938 RGD:7296939

NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332

G

complement C4-A

disease_progression

NCBI chrNW_004936727:1,556,204...1,570,084

G

LDL receptor related protein 1B

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283

G

leucine rich repeat kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936607:628,469...761,117
Ensembl chrNW_004936607:626,991...761,123

G

lactotransferrin

NCBI chrNW_004936596:344,287...373,788
Ensembl chrNW_004936596:344,274...373,952

G

mannose-6-phosphate receptor, cation dependent

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936870:300,742...310,876
Ensembl chrNW_004936870:302,166...307,134

G

mesencephalic astrocyte derived neurotrophic factor

susceptibility

NCBI chrNW_004936529:2,774,651...2,777,960
Ensembl chrNW_004936529:2,774,543...2,779,579

G

mitogen-activated protein kinase kinase 1

protein:increased expression:tumor:13/25 cases (52%)
inhibition suppressed tumor growth and vascularization in an RCC xenograft model

PMID:7664295 PMID:18172299

RGD:2292629 RGD:2292630

NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302

G

mitogen-activated protein kinase 1

susceptibility

DNA:missense mutation: :multiple

NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646

G

MET proto-oncogene, receptor tyrosine kinase

ClinVar Annotator: match by term: RENAL CELL CARCINOMA WITH PARANEOPLASTIC ERYTHROCYTOSIS | ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More...

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

matrix Gla protein

disease_progression

mRNA:increased expression:tumor:inversely related to tumor size (0.025

NCBI chrNW_004936587:2,601,419...2,605,848
Ensembl chrNW_004936587:2,601,312...2,605,870

G

melanocyte inducing transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936603:1,682,411...1,858,295
Ensembl chrNW_004936603:1,682,513...1,858,173

G

mutL homolog 1

protein:decreased expression:kidney

NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736

G

MLLT10 histone lysine methyltransferase DOT1L cofactor

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936520:6,176,784...6,366,436
Ensembl chrNW_004936520:6,176,599...6,366,428

G

matrix metallopeptidase 1

susceptibility
no_association

DNA:insertion:promoter:g.-1607insG (human)

PMID:12845675 PMID:17980059

RGD:7207023 RGD:7207082

NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857

G

matrix metallopeptidase 2

disease_progression

mRNA:decreased expression:kidney
protein:increased expression:kidney

PMID:17572184 PMID:18035688

RGD:2290358 RGD:2290359

NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851

G

matrix metallopeptidase 9

mRNA:increased expression:kidney

NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793

G

MOK protein kinase

mRNA:increased expression:kidney

NCBI chrNW_004936835:432,403...479,605
Ensembl chrNW_004936835:429,708...479,625

G

mesogenin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:13,129,883...13,130,464
Ensembl chrNW_004936493:13,129,883...13,130,464

G

mutS homolog 2

ClinVar Annotator: match by term: Renal adenocarcinoma

PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More...

NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356

G

methylenetetrahydrofolate reductase

susceptibility

DNA:missense mutation:cds:p.A222V (rs1801133) (human)

NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193

G

mechanistic target of rapamycin kinase

ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma

PMID:20190810 PMID:22729223 PMID:24631838 PMID:25599672 PMID:25741868 More...

NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342

G

mucin 1, cell surface associated

disease_progression

NCBI chrNW_004936580:4,691,870...4,694,092

G

mucin 4, cell surface associated

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936784:515,608...539,915

G

MYC proto-oncogene, bHLH transcription factor

protein:increased expression:kidney (rat)
mRNA:increased expression:kidney (human)

PMID:18055543 PMID:21982273

RGD:7207793 RGD:7207841

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

G

neuron navigator 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936568:5,694,326...6,275,112
Ensembl chrNW_004936568:5,920,421...6,275,133

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936470:16,051,291...16,102,563
Ensembl chrNW_004936470:16,051,015...16,102,585

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

CTD Direct Evidence: marker/mechanism
OMIM:300854

CTD
MouseDO
RGD

PMID:19487675 PMID:25401301

NCBI chrNW_004936657:3,536,212...3,622,999
Ensembl chrNW_004936657:3,536,141...3,623,821

G

NFE2 like bZIP transcription factor 2

ClinVar Annotator: match by term: Renal adenocarcinoma

NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262

G

NLR family pyrin domain containing 12

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936994:20,848...36,757
Ensembl chrNW_004936994:20,854...36,757

G

nicotinamide N-methyltransferase

mRNA:increased expression:kidney
mRNA:increased expression:kidney (human)

PMID:15682440 PMID:17070307

RGD:2299120 RGD:401793726

NCBI chrNW_004936612:333,421...351,202
Ensembl chrNW_004936612:333,421...351,202

G

nuclear receptor subfamily 3 group C member 1

severity
treatment

PMID:18181043 PMID:21531004

RGD:7174727 RGD:7174733

NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856

G

neuropilin 1

disease_progression

NCBI chrNW_004936574:1,694,433...1,834,720
Ensembl chrNW_004936574:1,694,336...1,834,720

G

8-oxoguanine DNA glycosylase

ClinVar Annotator: match by term: OGG1-related condition

PMID:25741868 PMID:28492532

NCBI chrNW_004936602:3,411,106...3,418,826
Ensembl chrNW_004936602:3,413,282...3,418,831

G

p21 (RAC1) activated kinase 1

protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936498:6,001,126...6,135,663
Ensembl chrNW_004936498:6,001,014...6,086,614

G

polybromo 1

NCBI chrNW_004936473:3,382,618...3,476,049
Ensembl chrNW_004936473:3,382,260...3,476,052

G

proliferating cell nuclear antigen

severity

NCBI chrNW_004936485:13,766,221...13,771,215

G

programmed cell death 1

disease_progression

NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587

G

platelet derived growth factor receptor alpha

disease_progression

protein:increased expression:kidney

NCBI chrNW_004936482:16,804,129...16,853,539
Ensembl chrNW_004936482:16,807,569...16,853,587

G

platelet derived growth factor receptor beta

mRNA:increased expression:kidney

PMID:15994946 PMID:16865223

RGD:2290496 RGD:2292198

NCBI chrNW_004936504:4,762,251...4,799,789
Ensembl chrNW_004936504:4,762,184...4,799,829

G

pyruvate dehydrogenase E1 subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:2,580,642...2,586,266
Ensembl chrNW_004936473:2,580,618...2,586,266

G

podoplanin

disease_progression

NCBI chrNW_004936474:1,751,159...1,779,011
Ensembl chrNW_004936474:1,750,944...1,781,156

G

pyridoxal dependent decarboxylase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936501:2,946,402...3,001,712
Ensembl chrNW_004936501:2,946,669...3,001,553

G

phosphatidylethanolamine binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936668:2,316,661...2,323,015

G

phosphoribosylformylglycinamidine synthase

NCBI chrNW_004936595:1,483,688...1,499,716
Ensembl chrNW_004936595:1,483,689...1,501,364

G

placental growth factor

disease_progression

protein:increased expression:plasma

NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142

G

phosphoglycerate kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936547:286,267...310,062
Ensembl chrNW_004936547:286,267...310,062

G

p53-induced death domain protein 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936888:565,889...571,273
Ensembl chrNW_004936888:565,912...571,247

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073

G

phosphoinositide-3-kinase regulatory subunit 1

disease_progression

NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537

G

plasminogen activator, urokinase

severity

mRNA:increased expression:kidney (human)

NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877

G

phospholipase D2

protein:increased expression:kidney

NCBI chrNW_004936677:2,870,664...2,883,545
Ensembl chrNW_004936677:2,870,660...2,883,567

G

prostate transmembrane protein, androgen induced 1

mRNA:increased expression:kidney

NCBI chrNW_004936530:429,059...439,847
Ensembl chrNW_004936530:429,045...439,866

G

PNKD metallo-beta-lactamase domain containing

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936569:799,963...865,462
Ensembl chrNW_004936569:799,926...865,700

G

proopiomelanocortin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936493:7,060,747...7,065,276
Ensembl chrNW_004936493:7,061,587...7,065,109

G

phosphoribosyl pyrophosphate amidotransferase

protein:increased activity:tumor (rat)

NCBI chrNW_004936482:18,606,124...18,648,989
Ensembl chrNW_004936482:18,606,124...18,648,681

G

PRAME nuclear receptor transcriptional regulator

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936619:1,748,337...1,751,748

G

proline rich mitotic checkpoint control factor

ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936580:5,927,575...5,954,636
Ensembl chrNW_004936580:5,927,847...5,953,796

G

proteasome 20S subunit beta 9

DNA:snp:promoter:g.-151G>T (human)

NCBI chrNW_004936476:25,894,313...25,899,132
Ensembl chrNW_004936476:25,894,027...25,899,319

G

phosphatase and tensin homolog

disease_progression

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma

PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 More...

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

prostaglandin-endoperoxide synthase 1

mRNA:increased expression:kidney

NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823

G

prostaglandin-endoperoxide synthase 2

disease_progression

mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism

PMID:12664575 PMID:12708469 PMID:17899436

RGD:2300204 RGD:2300212

NCBI chrNW_004936481:3,821,564...3,828,086

G

parvalbumin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936492:4,048,459...4,064,024
Ensembl chrNW_004936492:4,048,470...4,064,019

G

Ras association domain family member 1

DNA:hypermethylation:promoter

NCBI chrNW_004936529:1,857,177...1,866,198
Ensembl chrNW_004936529:1,857,145...1,867,260

G

RB transcriptional corepressor 1

disease_progression

NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney

PMID:12663495 PMID:17290398 PMID:18089796

RGD:2298755 RGD:2298771

NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813

G

ring finger protein 139

NCBI chrNW_004936470:23,157,312...23,168,565
Ensembl chrNW_004936470:23,152,765...23,168,571

G

ribosomal protein L14

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936473:29,402,874...29,406,065
Ensembl chrNW_004936473:29,402,813...29,410,978

G

ryanodine receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936801:1,185,615...1,298,416
Ensembl chrNW_004936801:1,185,733...1,298,289

G

scavenger receptor class B member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936558:530,828...555,098
Ensembl chrNW_004936558:530,828...552,892

G

succinate dehydrogenase complex iron sulfur subunit B

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma

PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More...

NCBI chrNW_004936474:3,993,224...4,021,359
Ensembl chrNW_004936474:3,990,778...4,021,423

G

SET domain containing 2, histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

PMID:22138691 PMID:23797736

NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373

G

secreted frizzled related protein 1

mRNA:decreased expression:kidney

NCBI chrNW_004936785:1,276,478...1,320,397
Ensembl chrNW_004936785:1,276,420...1,321,017

G

secreted frizzled related protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936576:604,174...612,440
Ensembl chrNW_004936576:604,069...613,021

G

SH3 and multiple ankyrin repeat domains 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936889:428,404...470,161
Ensembl chrNW_004936889:428,417...470,060

G

S-phase kinase associated protein 2

disease_progression

NCBI chrNW_004936518:5,635,856...5,664,057
Ensembl chrNW_004936518:5,637,331...5,664,778

G

solute carrier family 2 member 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713

G

solute carrier family 49 member 4

susceptibility

DNA:translocation:intron:t(2;3)(q35;q21)

NCBI chrNW_004937358:39,940...86,612

G

solute carrier family 5 member 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936500:8,284,631...8,296,387

G

SMAD family member 2

severity

protein:decreased expression:kidney

NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697

G

SMAD family member 4

severity

protein:decreased expression:kidney

NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123

G

SWI/SNF related BAF chromatin remodeling complex subunit C1

disease_progression

NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781

G

secreted protein acidic and cysteine rich

mRNA, protein:increased expression:kidney

NCBI chrNW_004936515:11,026,156...11,046,812
Ensembl chrNW_004936515:11,025,724...11,046,849

G

serine peptidase inhibitor Kazal type 1

disease_progression

protein:decreased expression:kidney
protein:increased expression:serum

PMID:10508484 PMID:11176522

RGD:2300387 RGD:2300388

NCBI chrNW_004936504:6,975,044...6,981,304
Ensembl chrNW_004936504:6,975,044...6,981,304

G

spectrin beta, non-erythrocytic 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936661:2,831,132...2,903,619
Ensembl chrNW_004936661:2,827,572...2,903,655

G

ST14 transmembrane serine protease matriptase

protein:increased expression:kidney

NCBI chrNW_004936572:2,137,820...2,182,674
Ensembl chrNW_004936572:2,137,332...2,182,742

G

suppression of tumorigenicity 7

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936589:1,899,714...2,119,063
Ensembl chrNW_004936589:1,899,687...2,111,047

G

signal transducer and activator of transcription 3

disease_progression

protein:increased phosphorylation:kidney
DNA:snp

PMID:12131365 PMID:17602083

RGD:2291913 RGD:2291917

NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402

G

spectrin repeat containing nuclear envelope protein 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936495:7,658,250...7,949,417

G

transgelin 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936740:689,745...697,145
Ensembl chrNW_004936740:689,595...699,763

G

telomerase reverse transcriptase

mRNA, protein:increased expression:kidney

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

tet methylcytosine dioxygenase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615

G

transcription factor binding to IGHM enhancer 3

ClinVar Annotator: match by term: Renal cell carcinoma

PMID:25741868 PMID:28492532 PMID:30595499 PMID:32409512 PMID:35346031 More...

NCBI chrNW_004936721:933,572...945,717
Ensembl chrNW_004936721:933,404...945,725

G

transferrin receptor

protein:increased expression:kidney, T cell
mRNA:decreased expression:kidney, T cell

PMID:8050820 PMID:12394762

RGD:2292024 RGD:2292025

NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543

G

transforming growth factor beta 1

disease_progression

protein:increased expression:peripheral blood

PMID:25499257 PMID:26631499 PMID:26749573

RGD:11560966 RGD:13506173 RGD:13506175

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

transglutaminase 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936561:3,178,244...3,207,551
Ensembl chrNW_004936561:3,178,293...3,207,561

G

thyroid hormone receptor alpha

DNA:mutations (human)

NCBI chrNW_004936490:15,188,341...15,206,032
Ensembl chrNW_004936490:15,193,150...15,206,784

G

thyroid hormone receptor beta

DNA:mutations (human)

NCBI chrNW_004936473:15,766,214...15,986,389
Ensembl chrNW_004936473:15,770,146...15,986,561

G

TIMP metallopeptidase inhibitor 1

disease_progression

protein:increased expression:kidney

NCBI chrNW_004936502:13,345,936...13,350,170
Ensembl chrNW_004936502:13,345,832...13,350,248

G

TIMP metallopeptidase inhibitor 2

disease_progression

mRNA:decreased expression:kidney
protein:increased expression:kidney

PMID:17572184 PMID:18035688

RGD:2290358 RGD:2290359

NCBI chrNW_004936594:3,232,433...3,244,241
Ensembl chrNW_004936594:3,232,355...3,244,241

G

TIMP metallopeptidase inhibitor 3

mRNA:decreased expression:kidney

NCBI chrNW_004936492:6,996,627...7,046,137
Ensembl chrNW_004936492:6,996,613...7,046,190

G

TIMP metallopeptidase inhibitor 4

mRNA:decreased expression:kidney

NCBI chrNW_004936602:1,488,993...1,496,108
Ensembl chrNW_004936602:1,489,545...1,495,478

G

tumor necrosis factor

PMID:19384924 PMID:19904265

RGD:2315113 RGD:2315119

NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766

G

TNF receptor superfamily member 1A

protein:increased expression:serum (human)

NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921

G

TNF receptor superfamily member 1B

NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

NCBI chrNW_004936593:212,642...230,645
Ensembl chrNW_004936593:212,532...230,651

G

tumor protein p53

disease_progression

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

PMID:1349175 PMID:1565143 PMID:1565144 PMID:1631137 PMID:1644930 More...

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

tumor protein p73

NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464

G

TSC complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936487:19,331,183...19,386,841
Ensembl chrNW_004936487:19,331,194...19,386,892

G

TSC complex subunit 2

treatment

DNA:nonsense mutations;missense mutations; splice-site mutation:multiple

PMID:10029074 PMID:10096549 PMID:18695678

RGD:11568655 RGD:11568661 RGD:68666

NCBI chrNW_004936694:1,958,152...1,993,373
Ensembl chrNW_004936694:1,958,154...1,993,363

G

thioredoxin interacting protein

DNA, mRNA, protein:hypermethylation, decreased expression:promoter, kidney

NCBI chrNW_004936867:722,544...726,595
Ensembl chrNW_004936867:722,514...726,617

G

thymidine phosphorylase

severity

protein:increased expression:kidney

PMID:12614261 PMID:16861722

RGD:2293717 RGD:2293723

NCBI chrNW_004936629:315,609...320,356
Ensembl chrNW_004936629:315,610...319,076

G

unc-5 netrin receptor C

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936687:2,600,635...2,951,407
Ensembl chrNW_004936687:2,607,112...2,756,094

G

vascular endothelial growth factor A

disease_progression

NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673

G

vascular endothelial growth factor C

NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559

G

von Hippel-Lindau tumor suppressor

ClinVar Annotator: match by term: RENAL CELL CARCINOMA WITH PARANEOPLASTIC ERYTHROCYTOSIS | ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis

PMID:7563486 PMID:7660122 PMID:7728151 PMID:7784063 PMID:7977367 More...

NCBI chrNW_004936602:3,135,790...3,140,622

G

vitelline membrane outer layer 1 homolog

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936677:2,903,520...2,904,458
Ensembl chrNW_004936677:2,900,666...2,904,463

G

von Willebrand factor

disease_progression

protein:increased expression:plasma

NCBI chrNW_004936709:1,578,137...1,741,877
Ensembl chrNW_004936709:1,579,096...1,741,754

G

WNT inhibitory factor 1

DNA:hypermethylation:promoter

NCBI chrNW_004936545:3,263,646...3,334,163
Ensembl chrNW_004936545:3,263,623...3,333,937

G

Wnt family member 11

mRNA:increased expression:tumor:increased in a single case

NCBI chrNW_004936498:4,909,041...4,927,482
Ensembl chrNW_004936498:4,908,978...4,927,165

G

Wnt family member 2

ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic

NCBI chrNW_004936589:1,825,209...1,866,898
Ensembl chrNW_004936589:1,825,209...1,866,889

G

X-linked inhibitor of apoptosis

disease_progression

protein:increased expression:kidney

NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116

G

X-ray repair cross complementing 1

susceptibility

DNA:SNP: :p.R399Q

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

Yip1 domain family member 3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936476:16,487,405...16,492,177
Ensembl chrNW_004936476:16,487,400...16,492,177

G

zinc finger protein 536

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936570:4,768,842...5,201,254
Ensembl chrNW_004936570:4,909,567...5,144,970

G

zinc finger protein 804A

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936506:12,164,004...12,450,483
Ensembl chrNW_004936506:12,164,469...12,167,690

Renal Cell Carcinoma 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ankyrin repeat, SAM and basic leucine zipper domain containing 1

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936589:1,756,616...1,799,810
Ensembl chrNW_004936589:1,756,616...1,799,580

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211

G

capping actin protein of muscle Z-line subunit alpha 2

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936589:2,194,332...2,234,547
Ensembl chrNW_004936589:2,194,332...2,234,653

G

CF transmembrane conductance regulator

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936589:1,565,933...1,719,208

G

catenin beta 1

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

chromosome unknown C11orf65 homolog

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936551:305,617...343,369
Ensembl chrNW_004936551:305,611...351,063

G

MET proto-oncogene, receptor tyrosine kinase

ClinVar Annotator: match by term: Renal cell carcinoma 1

PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 PMID:9731534 More...

NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179

G

mutS homolog 2

ClinVar Annotator: match by term: Renal cell carcinoma 1

PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More...

NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356

G

mechanistic target of rapamycin kinase

ClinVar Annotator: match by term: Renal cell carcinoma 1

PMID:25741868 PMID:28492532

NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342

G

proline rich mitotic checkpoint control factor

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936580:5,927,575...5,954,636
Ensembl chrNW_004936580:5,927,847...5,953,796

G

succinate dehydrogenase complex iron sulfur subunit B

ClinVar Annotator: match by term: Renal cell carcinoma 1

PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More...

NCBI chrNW_004936474:3,993,224...4,021,359
Ensembl chrNW_004936474:3,990,778...4,021,423

G

suppression of tumorigenicity 7

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936589:1,899,714...2,119,063
Ensembl chrNW_004936589:1,899,687...2,111,047

G

von Hippel-Lindau tumor suppressor

ClinVar Annotator: match by term: Renal cell carcinoma 1

PMID:7563486 PMID:7784063 PMID:7977367 PMID:7987306 PMID:8493574 More...

NCBI chrNW_004936602:3,135,790...3,140,622

G

Wnt family member 2

ClinVar Annotator: match by term: Renal cell carcinoma 1

NCBI chrNW_004936589:1,825,209...1,866,898
Ensembl chrNW_004936589:1,825,209...1,866,889

Renal Cell Carcinoma, Xp11-Associated

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

transcription factor binding to IGHM enhancer 3

ClinVar Annotator: match by term: Renal cell carcinoma, Xp11-associated

NCBI chrNW_004936721:933,572...945,717
Ensembl chrNW_004936721:933,404...945,725

Ruijs-Aalfs syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

SprT-like N-terminal domain

ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome | ClinVar Annotator: match by term: SPRTN-related condition

PMID:12503110 PMID:25261934 PMID:25741868 PMID:28492532

NCBI chrNW_004936484:19,391,685...19,402,938
Ensembl chrNW_004936484:19,391,420...19,402,944

serous cystadenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin dependent kinase inhibitor 1A

disease_progression

NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182

G

luteinizing hormone/choriogonadotropin receptor

mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.05)

NCBI chrNW_004936508:3,928,467...3,983,481
Ensembl chrNW_004936508:3,928,466...3,983,890

G

serum/glucocorticoid regulated kinase 1

mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.01)

NCBI chrNW_004936560:1,979,804...2,009,167
Ensembl chrNW_004936560:1,979,808...2,088,329

G

tumor protein p53

disease_progression

NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425

G

XPC complex subunit, DNA damage recognition and repair factor

disease_progression

DNA:SNPs: :rs1124303, rs3731108 (human)

NCBI chrNW_004936602:118,173...139,884
Ensembl chrNW_004936602:118,188...139,675

small intestine adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

mitogen-activated protein kinase kinase 1

NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302

G

mitogen-activated protein kinase kinase 2

NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090

Sporadic Papillary Renal Cell Carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

MYC proto-oncogene, bHLH transcription factor

severity

protein:increased expression:kidney (human)
mRNA:increased expression:renal cortex (human)

PMID:17409424 PMID:19384955

RGD:7240562 RGD:7240563

NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965

Thyroid Cancer, Nonmedullary, 4

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

forkhead box E1

ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 4

PMID:25381600 PMID:25741868 PMID:28444304 PMID:32428920

NCBI chrNW_004936524:6,619,128...6,620,278
Ensembl chrNW_004936524:6,619,128...6,620,278

Thyroid Cancer, Nonmedullary, 5

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

hyaluronan binding protein 2

susceptibility

ClinVar Annotator: match by term: HABP2-related condition | ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 5, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 5

PMID:12138371 PMID:12578864 PMID:15486068 PMID:25741868 PMID:26222560 More...

NCBI chrNW_004936486:3,987,746...4,004,632
Ensembl chrNW_004936486:3,974,035...4,004,632

Thyroid Carcinoma, Nonmedullary 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 1

NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523

G

NK2 homeobox 1

ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 1

PMID:19176457 PMID:25741868 PMID:28492532

NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566

G

pericentriolar material 1

ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 1

PMID:10980597 PMID:25741868

NCBI chrNW_004936554:7,906...86,187
Ensembl chrNW_004936554:7,938...87,756

G

RAD50 interactor 1

ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 1

PMID:16199547 PMID:25741868 PMID:28492532 PMID:31204009 PMID:33471991

NCBI chrNW_004936479:18,311,698...18,334,946
Ensembl chrNW_004936479:18,311,699...18,340,816

tubular adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

zinc finger homeobox 3

exacerbates

protein:increased expression:colon, nucleus, cytoplasm (human)

NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544

vipoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

menin 1

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936599:4,504,489...4,510,085
Ensembl chrNW_004936599:4,504,397...4,510,555

G

somatostatin

CTD Direct Evidence: therapeutic

NCBI chrNW_004936578:2,464,310...2,465,673
Ensembl chrNW_004936578:2,464,212...2,465,701

Term paths to the root

Path 1
Term	Annotations
disease	14633
disease of cellular proliferation	7025
cancer	5153
cell type cancer	3414
carcinoma	2935
adenocarcinoma	1510
Adenocarcinoid Tumor	0
Carcinoid Tumor +	10
Ductal Carcinoma +	251
Intestinal Type Adenocarcinoma	0
Ovine Pulmonary Adenomatosis	0
Skin Appendage Carcinoma	0
Urachal Adenocarcinoma	0
Wolffian duct adenocarcinoma	0
acinar cell carcinoma +	3
adenocarcinoma in situ	1
adenosquamous carcinoma +	3
adrenal cortical adenocarcinoma	0
adrenocortical carcinoma +	27
apocrine carcinoma +	0
appendix adenocarcinoma +	0
basophilic adenocarcinoma	0
bile duct adenocarcinoma +	119
bladder adenocarcinoma +	0
breast adenocarcinoma +	17
breast lobular carcinoma +	13
cervical adenocarcinoma +	4
choriocarcinoma +	7
clear cell adenocarcinoma +	4
colorectal adenocarcinoma +	114
cutaneous Paget's disease +	1
cystadenocarcinoma +	13
eccrine adenocarcinoma +	0
eccrine porocarcinoma	3
endometrial adenocarcinoma +	25
epididymis adenocarcinoma	0
esophagus adenocarcinoma +	41
ethmoid sinus adenocarcinoma	0
fallopian tube adenocarcinoma +	0
gallbladder adenocarcinoma +	3
gastric adenocarcinoma +	57
gastroesophageal adenocarcinoma +	1
granular cell carcinoma	0
hepatocellular carcinoma +	837
hepatoid adenocarcinoma +	0
jejunal adenocarcinoma	0
lacrimal gland adenocarcinoma +	0
large intestine adenocarcinoma +	65
lung adenocarcinoma +	306
lung combined type small cell adenocarcinoma	0
maxillary sinus adenocarcinoma	0
middle ear adenocarcinoma	0
mucinous adenocarcinoma +	8
nasal cavity adenocarcinoma	1
ovary adenocarcinoma +	10
pancreatic adenocarcinoma +	56
pancreatic endocrine carcinoma +	13
papillary adenocarcinoma +	43
prostate adenocarcinoma +	50
renal cell carcinoma +	331
renal pelvis adenocarcinoma	0
rete testis adenocarcinoma	0
scirrhous adenocarcinoma +	1
sebaceous adenocarcinoma	0
seminal vesicle adenocarcinoma	0
signet ring cell adenocarcinoma +	1
small intestine adenocarcinoma +	3
thymus adenocarcinoma +	0
thyroid gland adenocarcinoma +	50
tubular adenocarcinoma +	3
ureter adenocarcinoma	0
urethra adenocarcinoma +	0
villous adenocarcinoma	0
vulva adenocarcinoma +	0

paths to the root