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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:severe acute respiratory syndrome
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Accession:DOID:2945 term browser browse the term
Definition:A Coronavirus infection that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia. (DO)
Synonyms:exact_synonym: SARS;   SARS (Severe Acute Respiratory Syndrome);   SARS-CoV infection
 primary_id: MESH:D045169
 xref: GARD:9237;   ICD10CM:J12.81;   ICD9CM:079.82;   NCI:C85064
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
severe acute respiratory syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO RGD PMID:15784866 RGD:5128832 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:15381116 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment
susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
human gene in a mouse model
CTD PMID:14647384, PMID:16007097, PMID:16166518, PMID:16339146, PMID:19453650, PMID:19625462, PMID:23678171, PMID:24172901, PMID:24227843, PMID:26801988, PMID:31996437, PMID:32092392, PMID:32201080, PMID:32553273, PMID:17974127, PMID:16007097 RGD:32716426, RGD:30309965, RGD:30309202 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Anpep alanyl aminopeptidase, membrane disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Bpi bactericidal/permeability-increasing protein disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 3:154,741,627...154,768,584
Ensembl chr 3:154,741,631...154,768,640
JBrowse link
G C1qb complement C1q B chain disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C5ar1 complement C5a receptor 1 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Casp3 caspase 3 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO mRNA: increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
protein:increased expression:plasma (human)
CTD PMID:20484496, PMID:15888207, PMID:32553273, PMID:15602737, PMID:15356152, PMID:15781938, PMID:15657466, PMID:16195357 RGD:34201108, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO mRNA, protein: increased expression, altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 severity
treatment
ISO Severe Acute Respiratory Syndrome; DNA:transversion:5' utr:-28C>G (human)
protein:increased expression:bronchoalveolar lavage (human)
mRNA, protein: increased expression, altered expression:lung, brain (mouse)
protein:increased expression:plasma (human)
mRNA:increased expression:lung (mouse)
RGD PMID:19258635, PMID:15888207, PMID:15865221, PMID:32553273, PMID:15356152, PMID:15781938, PMID:16195357, PMID:32365944 RGD:4891448, RGD:34201108, RGD:33769580, RGD:32716426, RGD:30309221, RGD:30309220, RGD:30309218, RGD:30309207 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO mRNA:altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Cd14 CD14 molecule disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd209 CD209 molecule no_association ISO DNA:SNPs, haplotype:multiple RGD PMID:18697825 RGD:35673320 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324
JBrowse link
G Cd3e CD3e molecule ISO protein:increased expression:Tcell, testis (human) RGD PMID:16237152 RGD:27372876 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd4 Cd4 molecule disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd68 Cd68 molecule disease_progression ISO mRNA, protein:increased expression:lung (human)
protein:increased expression:macrophage, testis (human)
RGD PMID:19635508, PMID:16237152 RGD:5490168, RGD:27372876 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd9 CD9 molecule disease_progression ISO mRNA, protein:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 disease_progression ISO mRNA:decreased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Clec4g C-type lectin domain family 4, member G no_association ISO DNA:SNPs, haplotype:multiple RGD PMID:18697825 RGD:35673320 NCBI chr12:2,273,649...2,278,594
Ensembl chr12:2,273,941...2,277,169
JBrowse link
G Clec4m C-type lectin domain family 4 member M susceptibility
no_association
ISO DNA:repeats:exon 4: RGD PMID:16369534, PMID:18697825, PMID:18708672, PMID:17534355, PMID:17534354 RGD:35673327, RGD:35673320, RGD:36049808, RGD:36049807, RGD:36049806 NCBI chr12:2,817,633...2,826,303
Ensembl chr12:2,816,065...2,826,378
JBrowse link
G Ctsl cathepsin L ISO CTD Direct Evidence: marker/mechanism CTD PMID:16081529, PMID:16339146, PMID:22496216, PMID:23678171 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:19741068 RGD:4143520 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment
severity
disease_progression
ISO protein:increased expression:serum
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
mRNA, protein:increased expression:serum, lung (human)
mRNA, protein:increased expression:plasma, lung (human)
protein:increased expression:lung (human)
protein:increased expression:lung (mouse)
mRNA:increased expression:lung (mouse)
mRNA:decreased expression:lung (human)
RGD PMID:17052299, PMID:15865221, PMID:32553273, PMID:15602737, PMID:15356152, PMID:15781938, PMID:15657466, PMID:16195357, PMID:17129463, PMID:20231782, PMID:32365944, PMID:19635508 RGD:5135440, RGD:33769580, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218, RGD:30309217, RGD:30309216, RGD:30309207, RGD:5490168 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 treatment ISO RGD PMID:32553273 RGD:32716426 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO mRNA:altered expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP protein:increased expression:respiratory fluid/secretion RGD PMID:19741068 RGD:4143520 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 severity
treatment
ISO mRNA, protein:increased expression:lung
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:plasma (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
RGD PMID:19906920, PMID:15888207, PMID:16195357, PMID:15602737, PMID:15356152, PMID:15781938 RGD:4891446, RGD:34201108, RGD:30309218, RGD:32716399, RGD:30309221, RGD:30309220 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO mRNA:altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Egfr epidermal growth factor receptor severity ISO RGD PMID:28404843 RGD:38599178 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Fcer2 Fc fragment of IgE receptor II no_association ISO DNA:SNPs, haplotype:multiple RGD PMID:18697825 RGD:35673320 NCBI chr12:2,233,772...2,245,324
Ensembl chr12:2,233,778...2,245,324
JBrowse link
G Fgb fibrinogen beta chain ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf7 fibroblast growth factor 7 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fgg fibrinogen gamma chain ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fshb follicle stimulating hormone subunit beta ISO protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gh1 growth hormone 1 ISO protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Hp haptoglobin disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Ifnb1 interferon beta 1 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15200845, PMID:26861016, PMID:32553273 RGD:32716426 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma susceptibility
treatment
ISO DNA:polymorphism:cds:+874A>T(human)
protein:increased expression:peripheral blood mononuclear cells (human)
protein:increased expression:serum (human)
DNA:SNP:intron:+874A>T (rs2430561)(human)
RGD PMID:19258635, PMID:15865221, PMID:16781892, PMID:15602737, PMID:16672072, PMID:19526193, PMID:17872527 RGD:4891448, RGD:33769580, RGD:32716400, RGD:32716399, RGD:32716398, RGD:32716397, RGD:32716396 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 treatment IEP
ISO
protein:increased expression:serum, bronchoalveolar Lavage fluid (rat) RGD PMID:16409721, PMID:15865221 RGD:32726073, RGD:33769580 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum (human) RGD PMID:15602737 RGD:32716399 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha ISO mRNA:altered expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta severity ISO mRNA:altered expression:lung (mouse)
mRNA, protein:increased expression:lung, bronchoalveolar lavage (mouse)
RGD PMID:32364527, PMID:32365944 RGD:27226699, RGD:30309207 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il23a interleukin 23 subunit alpha ISO mRNA:decreased expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il6 interleukin 6 severity
disease_progression
treatment
ISO
IEP
protein:increased expression:serum (human)
protein:increased expression:blood (human)
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum, Bronchoalveolar Lavage fluid (rat)
RGD PMID:15657466, PMID:15472864, PMID:15888207, PMID:15865221, PMID:16409721, PMID:32553273, PMID:15271897 RGD:30309219, RGD:34888224, RGD:34201108, RGD:33769580, RGD:32726073, RGD:32716426, RGD:32716401 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 ISO mRNA:decreased expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Irf3 interferon regulatory factor 3 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)
CTD PMID:26861016, PMID:19635508 RGD:5490168 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Itga2b integrin subunit alpha 2b disease_progression ISO mRNA:decreased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Krt7 keratin 7 ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Lhb luteinizing hormone subunit beta ISO protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20484496 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20484496 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Msr1 macrophage scavenger receptor 1 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO RGD PMID:32365944 RGD:30309207 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 disease_progression ISO mRNA, protein:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253445 NCBI chr 2:196,139,724...196,172,055
Ensembl chr 2:196,139,755...196,171,713
JBrowse link
G Plat plasminogen activator, tissue type ISO protein:increased expression:plasma (human) RGD PMID:16274108 RGD:30309949 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plg plasminogen ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pomc proopiomelanocortin ISO protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Prl prolactin ISO protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Rab31 RAB31, member RAS oncogene family disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RT1-Da RT1 class II, locus Da disease_progression ISO mRNA:increased expression:lung RGD PMID:19635508 RGD:5490168 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO DNA:polymorphism:cds:HLA-DRB1*12 (human)
DNA:polymorphism:cds:HLA-DRB1*0301 (human)
RGD PMID:15243926, PMID:19445991 RGD:32716374, RGD:32716381 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G S100a8 S100 calcium binding protein A8 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G Serpina3m serpin family A member 3M ISO protein:increased expression:plasma RGD PMID:16649161 RGD:5147434 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO protein:increased expression:plasma RGD PMID:16649161 RGD:5147434 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISS MouseDO NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
IEP
protein:increased expression:serum (human)
protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)
RGD PMID:15271897, PMID:16409721 RGD:32716401, RGD:32726073 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thbd thrombomodulin ISO protein:increased expression:plasma (human) RGD PMID:16274108 RGD:30309949 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Tirap TIR domain containing adaptor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tlr2 toll-like receptor 2 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tmprss11d transmembrane serine protease 11D ISO CTD Direct Evidence: marker/mechanism CTD PMID:24227843 NCBI chr14:23,330,933...23,392,993
Ensembl chr14:23,330,933...23,392,991
JBrowse link
G Tmprss2 transmembrane serine protease 2 severity ISO CTD Direct Evidence: marker/mechanism CTD PMID:22496216, PMID:24227843, PMID:30626688, PMID:30626688 RGD:30309210 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:plasma (human)
protein:increased expression:bronchoalveolar lavage (human)
RGD PMID:14514395, PMID:15888207 RGD:30309961, RGD:34201108 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tshb thyroid stimulating hormone subunit beta ISO protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26801988 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vwf von Willebrand factor ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    syndrome 6996
      severe acute respiratory syndrome 90
Path 2
Term Annotations click to browse term
  disease 16058
    disease by infectious agent 1759
      viral infectious disease 1457
        RNA Virus Infections 1290
          Nidovirales Infections 972
            Coronaviridae Infections 971
              Coronavirus infectious disease 970
                severe acute respiratory syndrome 90
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.