Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:laryngeal squamous cell carcinoma
go back to main search page
Accession:DOID:2876 term browser browse the term
Definition:A laryngeal carcinoma that has_material_basis_in squamous cells. (DO)
Synonyms:exact_synonym: epidermoid carcinoma of the larynx;   squamous cell carcinoma of larynx
 xref: NCI:C4044;   ORDO:494550
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
laryngeal squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A IEP RGD PMID:15646812 RGD:8662837 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G EGFR epidermal growth factor receptor disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 severity IEP associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr17:12,020,822...12,143,828
Ensembl chr17:12,020,829...12,143,830
JBrowse link
G MLH1 mutL homolog 1 disease_progression IEP mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 3:36,993,487...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP RGD PMID:17786346 RGD:5130203 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MSH2 mutS homolog 2 disease_progression IEP mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP DNA:polymorphisms: : RGD PMID:19922706 PMID:16155914 RGD:5131602, RGD:5131856 NCBI chr 8:18,386,585...18,401,219
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit severity IEP associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 20259
    disease of cellular proliferation 8107
      cancer 5490
        cell type cancer 3785
          carcinoma 3139
            squamous cell carcinoma 527
              laryngeal squamous cell carcinoma 11
                larynx verrucous carcinoma + 0
Path 2
Term Annotations click to browse term
  disease 20259
    disease of anatomical entity 18860
      nervous system disease 14840
        sensory system disease 6162
          Otorhinolaryngologic Diseases 1470
            Otorhinolaryngologic Neoplasms 217
              Laryngeal Neoplasms 26
                larynx cancer 16
                  laryngeal carcinoma 11
                    laryngeal squamous cell carcinoma 11
                      larynx verrucous carcinoma + 0
paths to the root