Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:laryngeal squamous cell carcinoma
go back to main search page
Accession:DOID:2876 term browser browse the term
Definition:A laryngeal carcinoma that has_material_basis_in squamous cells. (DO)
Synonyms:exact_synonym: epidermoid carcinoma of the larynx;   squamous cell carcinoma of larynx
 xref: NCI:C4044;   ORDO:494550
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
laryngeal squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A ISO RGD PMID:15646812 RGD:8662837 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281
JBrowse link
G EGFR epidermal growth factor receptor disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296
JBrowse link
G MLH1 mutL homolog 1 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr23:6,889,108...6,938,117
Ensembl chr23:6,889,135...6,938,116
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:17786346 RGD:5130203 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113
JBrowse link
G MSH2 mutS homolog 2 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13825
    disease of cellular proliferation 6640
      cancer 4785
        cell type cancer 3282
          carcinoma 2812
            squamous cell carcinoma 493
              laryngeal squamous cell carcinoma 10
                larynx verrucous carcinoma + 0
Path 2
Term Annotations click to browse term
  disease 13825
    disease of anatomical entity 13482
      nervous system disease 11174
        sensory system disease 5167
          Otorhinolaryngologic Diseases 1230
            Otorhinolaryngologic Neoplasms 204
              Laryngeal Neoplasms 21
                larynx cancer 14
                  laryngeal carcinoma 10
                    laryngeal squamous cell carcinoma 10
                      larynx verrucous carcinoma + 0
paths to the root