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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:asthma
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Accession:DOID:2841 term browser browse the term
Definition:A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Synonyms:exact_synonym: AS1;   asthmas;   bronchial asthma
 narrow_synonym: ASTHMA, DIMINISHED RESPONSE TO ANTILEUKOTRIENE TREATMENT IN;   adult onset asthma;   airway hyperresponsiveness
 related_synonym: ASRT1;   ASRT2;   ASRT3;   ASRT4;   ASRT5;   ASRT6;   ASRT7;   ASRT8;   Asthma-Related Traits, Susceptibility To, 1;   Asthma-Related Traits, Susceptibility To, 2;   Asthma-Related Traits, Susceptibility To, 3;   Asthma-Related Traits, Susceptibility To, 4;   Asthma-Related Traits, Susceptibility To, 5;   Asthma-Related Traits, Susceptibility To, 6;   Asthma-Related Traits, Susceptibility To, 7;   Asthma-Related Traits, Susceptibility To, 8;   allergic airway inflammation;   asthma and allergic rhinitis, susceptibility to;   asthma and atopy, susceptibility to;   asthma, protection against;   asthma, susceptibility to;   asthma-traits, susceptibility to asthma, protection against;   beta-2-adrenoreceptor agonist, reduced response to;   childhood athma, susceptibility to;   rhinoconjunctivitis, susceptibility to
 primary_id: MESH:D001249
 alt_id: MIM:600807;   MIM:601690;   MIM:607277;   MIM:608584;   MIM:609958;   MIM:610906;   MIM:611064;   MIM:611403;   MIM:611960;   MIM:613207
 xref: EFO:0000270;   EFO:0005414;   EFO:1002011;   GARD:10246;   ICD10CM:J45;   ICD9CM:493;   MONDO:0004979;   NCI:C28397
For additional species annotation, visit the Alliance of Genome Resources.

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asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:18931056 RGD:5128825 NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:16008680 PMID:19771478 RGD:5128831 RGD:5128835 NCBI chrNW_004936570:1,315,192...1,322,719 JBrowse link
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chrNW_004936569:4,774,602...4,842,906
Ensembl chrNW_004936569:4,774,542...4,844,494 		JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Adam33 ADAM metallopeptidase domain 33 susceptibility
disease_progression
no_association		 ISO DNA:polymorphism: :p.M764T (human)
mRNA:increased expression:lung
DNA:SNPs: :multiple (human)
mRNA:increased expression:bronchus
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
DNA:SNPs (human)		 RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chrNW_004936485:15,005,329...15,018,063
Ensembl chrNW_004936485:15,007,485...15,017,497 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:respiratory tract
mRNA:increased expression:bronchus		 RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 NCBI chrNW_004936486:19,389,925...19,403,577
Ensembl chrNW_004936486:19,391,324...19,402,332 		JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004936643:47,830...338,891
Ensembl chrNW_004936643:47,837...339,007 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chrNW_004936478:7,278,081...7,322,970
Ensembl chrNW_004936478:7,278,147...7,318,458 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928 		JBrowse link
G Adora1 adenosine A1 receptor ISO protein:increased expression:bronchus
DNA:SNPs: :1405C>T (human)		 RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532 		JBrowse link
G Adora2a adenosine A2a receptor ISO mRNA:decreased expression:aorta
DNA:SNP (human)		 RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chrNW_004936619:597,970...618,564
Ensembl chrNW_004936619:608,441...616,779 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :-1023A>G (human)		 ClinVar
RGD		 PMID:8383511 PMID:15284533 PMID:16596417 PMID:19638684 RGD:4145081 NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210 		JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment
onset		 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)		 RGD
CTD		 PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147 		JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:19080339 RGD:5147457 NCBI chrNW_004936519:6,831,096...6,873,977
Ensembl chrNW_004936519:6,831,096...6,873,985 		JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chrNW_004936479:13,252,678...13,255,570
Ensembl chrNW_004936479:13,252,678...13,255,570 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:18692885 PMID:19628725 RGD:5509605 RGD:5509784 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
treatment
severity		 ISO DNA:polymorphism:promoter (human)
DNA:repeat:promoter (human)		 RGD
OMIM		 PMID:10369259 PMID:12911785 PMID:16364163 PMID:20128419 RGD:4890407 RGD:4890415 RGD:5147465 RGD:734557 NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association
susceptibility		 ISO DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphism:promoter (human)
mRNA:increased expression:blood, leukocyte
DNA:SNPs (human)
protein:increased expression:lung
DNA:SNP: :rs10507391 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)		 RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chrNW_004936472:25,477,094...25,502,823
Ensembl chrNW_004936472:25,477,010...25,502,840 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chrNW_004936487:3,399,792...3,412,088 JBrowse link
G Ang angiogenin severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chrNW_004936880:39,372...40,070 JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413 		JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chrNW_004936598:1,276,599...1,283,612
Ensembl chrNW_004936598:1,274,565...1,283,746 		JBrowse link
G Arg2 arginase 2 susceptibility
severity		 ISO DNA:SNPs (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3742879, rs17249437 (human)
mRNA:increased expression:lung (mouse)		 RGD
CTD		 PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chrNW_004936495:11,004,296...11,045,467
Ensembl chrNW_004936495:11,004,176...11,045,472 		JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bdkrb2 bradykinin receptor B2 onset ISO protein:increased expression:blood, eosinophil
DNA:polymorphism:exon (human)		 RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chrNW_004936604:548,844...551,031
Ensembl chrNW_004936604:548,847...549,956 		JBrowse link
G Bdnf brain derived neurotrophic factor severity
susceptibility		 ISO protein:increased expression:plasma
protein:decreased expression:blood, eosinophil
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)		 RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chrNW_004936580:5,480,023...5,482,288
Ensembl chrNW_004936580:5,481,355...5,482,155 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004936687:2,346,601...2,595,283
Ensembl chrNW_004936687:2,503,777...2,597,522 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004936726:1,543,263...1,711,422
Ensembl chrNW_004936726:1,543,245...1,704,541 		JBrowse link
G C3 complement C3 severity ISO DNA:SNPs: :multiple (human)
DNA:SNP:intron:rs11569562 (human)
protein:increased expression:serum
protein:increased expression:respiratory system fluid/secretion
Interaction with IL4RA
DNA:SNP: :4896C>T (human)		 RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C3ar1 complement C3a receptor 1 severity ISO mRNA:increased expression:lung
protein:increased expression:lung, leukocyte		 RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chrNW_004936892:347,547...355,143
Ensembl chrNW_004936892:347,842...349,296 		JBrowse link
G C5 complement C5 severity ISO mRNA:decreased expression:lung RGD PMID:10973279 PMID:11591795 PMID:15278436 PMID:20143644 PMID:20802484 RGD:1600651 RGD:5129512 RGD:5129681 RGD:5129706 RGD:5130158 NCBI chrNW_004936487:9,391,774...9,474,168
Ensembl chrNW_004936487:9,391,804...9,474,159 		JBrowse link
G C5ar1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract		 RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chrNW_004936664:1,026,216...1,033,438
Ensembl chrNW_004936664:1,032,304...1,033,374 		JBrowse link
G Card11 caspase recruitment domain family member 11 susceptibility ISO ClinVar Annotator: match by term: Asthma RGD
ClinVar		 PMID:16751370 PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 More... RGD:11100037 NCBI chrNW_004936823:580,438...621,298
Ensembl chrNW_004936823:581,955...621,208 		JBrowse link
G Carm1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004936659:1,071,883...1,120,917
Ensembl chrNW_004936659:1,090,164...1,123,920 		JBrowse link
G Cat catalase severity ISO protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-21A>T (human)
protein:increased expression:erythrocyte
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-262C>T (human)		 RGD
CTD		 PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chrNW_004936538:781,687...784,199
Ensembl chrNW_004936538:781,687...784,199 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung		 RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chrNW_004936475:9,475,013...9,476,326
Ensembl chrNW_004936475:9,474,961...9,476,398 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chrNW_004936524:2,765,271...2,767,259
Ensembl chrNW_004936524:2,765,267...2,767,385 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO associated with Allergic Rhinitis;protein:increased expression:serum
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chrNW_004936525:8,238,128...8,240,974
Ensembl chrNW_004936525:8,237,831...8,240,974 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion		 RGD PMID:10384142 PMID:15993846 PMID:18316417 PMID:18684970 RGD:2306304 RGD:4145489 RGD:4891474 RGD:4891475 NCBI chrNW_004936475:9,432,505...9,436,240
Ensembl chrNW_004936475:9,432,505...9,436,240 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 susceptibility ISO protein:increased expression:plasma
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
DNA:SNPs: :179T>C, 275C>T (human)		 RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chrNW_004936543:2,400,743...2,403,558
Ensembl chrNW_004936543:2,400,768...2,403,217 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 treatment ISO protein:increased expression:plasma
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
DNA:SNPs: :77C>T, 2497T>G (human)		 RGD PMID:15207712 PMID:16304252 PMID:18712274 PMID:25399816 PMID:25530546 RGD:11081163 RGD:11087575 RGD:4891483 RGD:4891495 RGD:5130930 NCBI chrNW_004936543:2,414,948...2,416,922
Ensembl chrNW_004936543:2,414,850...2,416,953 		JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chrNW_004936524:2,743,106...2,743,759
Ensembl chrNW_004936524:2,743,068...2,743,746 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chrNW_004936480:18,819,012...18,824,981
Ensembl chrNW_004936480:18,810,406...18,824,894 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
DNA:transition:5' utr:-403G>A (human)
protein:increased expression:smooth muscle cell		 RGD
CTD		 PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)		 RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004936473:23,321,167...23,323,075 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004936489:16,669,297...16,689,451
Ensembl chrNW_004936489:16,669,297...16,689,451 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004936473:28,590,471...28,591,538
Ensembl chrNW_004936473:28,590,471...28,591,538 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chrNW_004936695:55,788...59,251
Ensembl chrNW_004936695:55,788...59,251 		JBrowse link
G Cd14 CD14 molecule no_association
susceptibility
severity		 ISO DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)		 RGD
CTD		 PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chrNW_004936531:9,572,392...9,575,771
Ensembl chrNW_004936531:9,571,796...9,575,923 		JBrowse link
G Cd274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602 		JBrowse link
G Cd28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chrNW_004936631:335,411...363,407
Ensembl chrNW_004936631:335,411...363,407 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403 		JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chrNW_004936536:6,462,080...6,483,450 JBrowse link
G Cd86 CD86 molecule treatment ISO protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
protein:increased expression:lung, alveolar macrophage (mouse)
DNA:snp:exon:p.I179V rs2681417 (human)		 RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chrNW_004936536:8,414,491...8,481,712 JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203 		JBrowse link
G Cdhr3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004936479:17,910,443...17,975,797
Ensembl chrNW_004936479:17,910,570...17,966,225 		JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chrNW_004936589:1,565,933...1,719,208 JBrowse link
G Chat choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chrNW_004936728:653,654...702,433
Ensembl chrNW_004936728:654,638...700,213 		JBrowse link
G Chi3l1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar		 PMID:18403759 NCBI chrNW_004936567:1,411,080...1,418,332
Ensembl chrNW_004936567:1,411,037...1,418,801 		JBrowse link
G Chia chitinase acidic no_association ISO mRNA:increased expression:lung (mouse)
DNA:snps:multiple (human)
DNA:snps:5' utr, cds:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)		 RGD PMID:14734765 PMID:15192232 PMID:16179638 PMID:19548841 PMID:20226308 RGD:4985150 RGD:4990463 RGD:4996473 RGD:5024921 RGD:5024922 NCBI chrNW_004939091:1,194...12,273
Ensembl chrNW_004939091:1,190...12,272 		JBrowse link
G Chml CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chrNW_004936526:8,833,921...8,844,484 JBrowse link
G Chrm1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chrNW_004936581:387,939...400,740
Ensembl chrNW_004936581:387,705...400,740 		JBrowse link
G Chrm2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chrNW_004936592:1,396,939...1,525,255
Ensembl chrNW_004936592:1,521,547...1,522,947 		JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chrNW_004936484:13,953,141...14,373,174
Ensembl chrNW_004936484:13,954,887...13,956,659 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chrNW_004936636:33,933...78,990
Ensembl chrNW_004936636:33,673...79,194 		JBrowse link
G Clca1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chrNW_004936865:155,284...188,988 JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chrNW_004936540:373,889...401,535
Ensembl chrNW_004936540:373,889...401,535 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)		 RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chrNW_004936541:2,288,847...2,333,129
Ensembl chrNW_004936541:2,288,841...2,331,689 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chrNW_004936478:6,901,098...6,947,719
Ensembl chrNW_004936478:6,899,017...6,947,790 		JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606 		JBrowse link
G Csf2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum		 RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chrNW_004936492:3,929,589...3,974,070 JBrowse link
G Csf3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 severity
treatment
no_association		 ISO DNA:SNPs: :multiple (human)
protein:increased expression:serum
DNA:SNP: :rs3087243 (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:polymorphism:promoter:-318C>T (human)		 RGD
CTD		 PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643 		JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chrNW_004936521:10,482,434...10,936,554 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chrNW_004936475:9,443,851...9,454,715
Ensembl chrNW_004936475:9,443,733...9,455,062 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:polymorphisms: :p.V249I, p.T280M (human)
DNA:SNPs: :p.V249I, rs2669849 (human)		 RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chrNW_004936473:28,508,726...28,535,640
Ensembl chrNW_004936473:28,510,523...28,535,627 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chrNW_004936597:2,746,415...2,754,169
Ensembl chrNW_004936597:2,746,296...2,754,716 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chrNW_004936676:33,580...40,323
Ensembl chrNW_004936676:32,128...40,329 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 susceptibility
severity		 ISO DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell		 RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chrNW_004936762:66,636...69,694
Ensembl chrNW_004936762:66,636...69,373 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 severity
no_association		 ISO mRNA, protein:increased expression:respiratory system mucosa
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNP: :927T>C (human)		 RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16387808 PMID:16630147 More... RGD:4781449 RGD:4781742 RGD:4782072 RGD:4784257 RGD:4843543 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116 NCBI chrNW_004936547:479,261...504,757 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :-1220A>C (human)
DNA:polymorphism: :601A>G (human)		 RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chrNW_004936565:1,917,970...1,919,027 JBrowse link
G Dcn decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chrNW_004936507:7,887,259...7,923,055
Ensembl chrNW_004936507:7,884,654...7,922,961 		JBrowse link
G Defb1 defensin beta 1 susceptibility ISO DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
DNA:SNP: :-1816 T>C (human)		 RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chrNW_004936615:4,780,229...4,790,516 JBrowse link
G Dnah5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004936665:2,267,272...2,545,765
Ensembl chrNW_004936665:2,314,175...2,545,579 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract: 		CTD
RGD		 PMID:23196709 PMID:23423710 RGD:9588646 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 ISO DNA:SNP:exon (human)
DNA:SNP: :rs10208402 (human)
protein:increased expression:bronchus
DNA:SNPs (human)		 RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chrNW_004936469:53,950,034...54,548,724
Ensembl chrNW_004936469:53,948,570...54,548,747 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chrNW_004936588:2,420,859...2,425,473
Ensembl chrNW_004936588:2,421,934...2,425,207 		JBrowse link
G Edn1 endothelin 1 ISO Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
DNA:transition:intron:g.4124T>C (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772 		JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chrNW_004936535:1,950,117...2,005,786
Ensembl chrNW_004936535:1,949,941...2,005,910 		JBrowse link
G Ednrb endothelin receptor type B ISO mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)		 RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chrNW_004936511:3,446,864...3,478,434
Ensembl chrNW_004936511:3,446,839...3,478,434 		JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (mouse)
protein:increased expression:lung epithelium (rat)
protein:increased expression:bronchial epithelium (human)		 RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528 		JBrowse link
G Egr1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)		 RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chrNW_004936559:3,924,185...3,981,907
Ensembl chrNW_004936559:3,924,185...3,983,028 		JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286 		JBrowse link
G Epx eosinophil peroxidase disease_progression
severity		 ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chrNW_004936490:4,876,857...4,887,275
Ensembl chrNW_004936490:4,876,877...4,887,275 		JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chrNW_004936495:7,956,168...8,018,356
Ensembl chrNW_004936495:7,956,766...8,004,357 		JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus		 RGD PMID:21658190 PMID:21711961 RGD:5147753 RGD:5147783 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chrNW_004936549:142,281...153,575
Ensembl chrNW_004936549:141,512...153,602 		JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia severity ISO Fatal asthma subjects
Asthma symptoms persistent despite steroids		 RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chrNW_004936740:1,201,370...1,206,871 JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chrNW_004937131:15,542...22,099 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chrNW_004936476:23,611,166...23,702,283
Ensembl chrNW_004936476:23,640,355...23,700,314 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308 		JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chrNW_004936484:6,780,692...6,800,883
Ensembl chrNW_004936484:6,780,692...6,800,966 		JBrowse link
G Gc GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chrNW_004936598:3,220,029...3,256,091
Ensembl chrNW_004936598:3,219,991...3,261,629 		JBrowse link
G Gsdmb gasdermin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004936490:15,058,009...15,066,781 JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chrNW_004936704:1,233,909...1,236,864
Ensembl chrNW_004936704:1,233,780...1,237,329 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chrNW_004936600:1,907,396...1,925,256
Ensembl chrNW_004936600:1,907,517...1,925,235 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility
severity
disease_progression
no_association		 ISO DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:p.I105V (rs1695) (human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:SNP: :p.A114V (human)
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:polymorphism:exon:p.I105V (human)		 RGD
CTD		 PMID:10806136 PMID:11994713 PMID:15693909 PMID:16176403 PMID:16870661 More... RGD:4140946 RGD:4140947 RGD:4140951 RGD:4142519 RGD:4142526 RGD:5490985 RGD:5490991 RGD:5490999 NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chrNW_004936515:6,030,402...6,051,161 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chrNW_004936679:2,448,676...2,474,641
Ensembl chrNW_004936679:2,448,390...2,474,641 		JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chrNW_004936471:12,303,802...12,324,613
Ensembl chrNW_004936471:12,304,130...12,324,570 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chrNW_004936549:1,378,536...1,400,501
Ensembl chrNW_004936549:1,378,736...1,400,532 		JBrowse link
G Hmox1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311 		JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to RGD
OMIM
ClinVar		 PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 More... RGD:5128885 RGD:5128887 RGD:5128888 NCBI chrNW_004936469:38,125,877...38,166,429
Ensembl chrNW_004936469:38,122,454...38,166,398 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chrNW_004936475:17,882,663...17,888,708
Ensembl chrNW_004936475:17,882,575...17,887,748 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chrNW_004936565:335,238...394,683
Ensembl chrNW_004936565:334,393...394,715 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:aorta (mouse)
protein:increased expression:lung, serum (rat)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)		 RGD
CTD		 PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174 		JBrowse link
G Ifng interferon gamma treatment
resistance		 ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chrNW_004936560:4,519,858...4,545,763
Ensembl chrNW_004936560:4,519,474...4,545,796 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chrNW_004936490:14,939,693...15,025,728
Ensembl chrNW_004936490:14,939,776...15,025,728 		JBrowse link
G Il10 interleukin 10 treatment
susceptibility		 ISO protein:decreased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)		 RGD
CTD		 PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502 		JBrowse link
G Il12a interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chrNW_004936519:6,166,060...6,180,652
Ensembl chrNW_004936519:6,175,261...6,180,396 		JBrowse link
G Il12b interleukin 12B severity
susceptibility		 ISO DNA:polymorphisms:introns:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter
DNA:polymorphisms:promoter, 3'utr:		 RGD
ClinVar		 PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chrNW_004936515:4,056,214...4,066,121
Ensembl chrNW_004936515:4,056,214...4,065,076 		JBrowse link
G Il13 interleukin 13 susceptibility
no_association
severity		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:cds:p.R130Q (human)
DNA:polymorphism: :c.-1055C>T (human)
protein:increased expression:sputum
protein:increased expression:serum		 OMIM
ClinVar
RGD		 PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 no_association ISO DNA:polymorphism: :1050C>T (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :1398A>G (human)		 RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655 NCBI chrNW_004936479:11,052,077...11,108,915
Ensembl chrNW_004936479:11,050,249...11,108,909 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum		 RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chrNW_004936499:860,179...883,884
Ensembl chrNW_004936499:863,599...883,855 		JBrowse link
G Il15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197 		JBrowse link
G Il16 interleukin 16 no_association
severity		 ISO DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion		 RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chrNW_004936483:19,417,580...19,512,654
Ensembl chrNW_004936483:19,418,086...19,512,639 		JBrowse link
G Il17a interleukin 17A susceptibility ISO protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:sputum
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum		 RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008 		JBrowse link
G Il17rb interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chrNW_004936473:4,512,461...4,524,452
Ensembl chrNW_004936473:4,512,510...4,524,236 		JBrowse link
G Il18 interleukin 18 severity
susceptibility
disease_progression		 ISO DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)
protein:increased expression:serum
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)		 RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189 		JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)		 RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chrNW_004936713:1,038,985...1,075,770
Ensembl chrNW_004936713:1,038,877...1,075,811 		JBrowse link
G Il19 interleukin 19 ISO protein:increased expression:serum
mRNA, protein:increased expression:lung, serum		 RGD PMID:15557163 RGD:5037236 NCBI chrNW_004936557:5,765,093...5,769,853
Ensembl chrNW_004936557:5,765,093...5,769,853 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil		 RGD
CTD		 PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il1rl1 interleukin 1 receptor like 1 susceptibility
severity		 ISO protein:increased expression:serum
DNA:SNP: :rs1420101 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)		 RGD
CTD		 PMID:11463601 PMID:17407196 PMID:17623648 PMID:19179489 PMID:19198610 More... RGD:5144235 RGD:5144237 RGD:5144239 RGD:5144240 RGD:5144242 RGD:5144243 RGD:5144244 RGD:5144245 NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity		 ISO DNA:SNPs: :rs447713, rs3087271 (human)
DNA:SNP: :rs2234678 (human)
DNA:polymorphism:intron (human)
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA, protein:repeat, decreased expression (human)		 RGD
CTD		 PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340 		JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625 		JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883 		JBrowse link
G Il22 interleukin 22 treatment
severity		 ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell		 RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chrNW_004936545:6,227,118...6,231,745
Ensembl chrNW_004936545:6,227,118...6,231,745 		JBrowse link
G Il23r interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chrNW_004936591:4,365,598...4,425,053
Ensembl chrNW_004936591:4,365,762...4,425,005 		JBrowse link
G Il25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chrNW_004936722:997,476...1,000,881
Ensembl chrNW_004936722:996,960...1,003,201 		JBrowse link
G Il27 interleukin 27 treatment
susceptibility		 ISO DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum		 RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491 NCBI chrNW_004936501:11,972,715...11,978,152
Ensembl chrNW_004936501:11,973,385...11,976,583 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chrNW_004936659:2,706,037...2,720,486
Ensembl chrNW_004936659:2,705,985...2,722,748 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chrNW_004936484:8,514,333...8,555,392
Ensembl chrNW_004936484:8,544,062...8,555,332 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chrNW_004936492:3,795,940...3,805,822
Ensembl chrNW_004936492:3,795,940...3,805,774 		JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)		 RGD PMID:15372320 PMID:24684517 RGD:13506914 RGD:13506916 NCBI chrNW_004936647:3,102,922...3,104,758 JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease		 CTD
RGD		 PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470 		JBrowse link
G Il4r interleukin 4 receptor susceptibility
disease_progression
severity		 ISO DNA:polymorphism::-1902G/A (human)
OMIM:600807
DNA:polymorphism:cds:p. S478P (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:SNPs: :multiple
DNA:polymorphism:cds:p.Q576R (human)
protein:increased secretion:plasma
DNA:mutation:cds:p.Q576R (mouse)		 RGD
MouseDO		 PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818 		JBrowse link
G Il5 interleukin 5 treatment
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-703C>T (human)
protein: increased levels: sputum
protein:increased expression:lungs, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion		 CTD
RGD		 PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chrNW_004936647:2,647,982...2,651,477
Ensembl chrNW_004936647:2,648,241...2,651,430 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)		 RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chrNW_004936577:2,776,608...2,797,303
Ensembl chrNW_004936577:2,776,721...2,797,300 		JBrowse link
G Il6 interleukin 6 ISO associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885 		JBrowse link
G Il9 interleukin 9 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm		 RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chrNW_004936597:2,983,953...2,986,975
Ensembl chrNW_004936597:2,983,953...2,986,975 		JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chrNW_004936501:829,236...840,130
Ensembl chrNW_004936501:829,236...840,048 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar		 PMID:17503328 NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806 		JBrowse link
G Irf1 interferon regulatory factor 1 susceptibility
no_association		 ISO protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)		 RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636 		JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chrNW_004936664:3,477,750...3,482,489
Ensembl chrNW_004936664:3,475,543...3,481,533 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
G Itgb6 integrin subunit beta 6 ISO OMIM:600807 MouseDO NCBI chrNW_004936469:18,581,855...18,650,109
Ensembl chrNW_004936469:18,581,840...18,650,123 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chrNW_004936577:3,896,455...4,198,396
Ensembl chrNW_004936577:3,896,390...4,198,411 		JBrowse link
G Kdr kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002 		JBrowse link
G Kif3a kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004936647:2,461,017...2,502,550
Ensembl chrNW_004936647:2,461,138...2,501,871 		JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chrNW_004936490:16,440,723...16,444,679
Ensembl chrNW_004936490:16,440,693...16,444,791 		JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334 		JBrowse link
G Lgals3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chrNW_004936697:20,861...38,568
Ensembl chrNW_004936697:27,145...38,586 		JBrowse link
G LOC101955076 low affinity immunoglobulin gamma Fc region receptor III-A susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chrNW_004937131:42,523...49,533 JBrowse link
G LOC101958908 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907 		JBrowse link
G LOC101961588 cytochrome P450 2D17 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphisms: :
DNA:haplotype
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:13506911 RGD:5143938 NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145 		JBrowse link
G LOC101964209 C-C chemokine receptor type 1 severity ISO associated with Respiratory Syncytial Virus Infections
mRNA:increased expression:lung		 RGD PMID:15593301 PMID:15654816 RGD:5688158 RGD:5688159 NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186 		JBrowse link
G LOC101967032 cytochrome b-245 light chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)		 RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chrNW_004936641:1,036,967...1,044,954
Ensembl chrNW_004936641:1,036,967...1,044,991 		JBrowse link
G LOC101968486 HLA class II histocompatibility antigen, DQ alpha 1 chain susceptibility ISO DNA:polymorphism: :rs3916765(human) RGD PMID:20159242 RGD:13506913 NCBI chrNW_004936727:373,464...378,784 JBrowse link
G LOC101968920 eotaxin severity
susceptibility
treatment		 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung
protein:increased expression:plasma		 RGD
CTD
OMIM		 PMID:9034156 PMID:16304252 PMID:17060636 PMID:17074272 PMID:18250471 More... RGD:4145387 RGD:4145392 RGD:4145451 RGD:4145461 RGD:4891485 RGD:5130930 RGD:7248416 NCBI chrNW_004936538:835,436...848,907
Ensembl chrNW_004936538:835,859...837,710
Ensembl chrNW_004936538:835,859...837,710 		JBrowse link
G LOC101968921 angiotensin-converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19383228 PMID:19484664 RGD:4140913 RGD:4140919 NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177 		JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chrNW_004936727:540,225...544,968
Ensembl chrNW_004936727:540,217...545,036 		JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332 		JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:leukocyte		 CTD
RGD		 PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102 		JBrowse link
G LOC101976500 haptoglobin ISO RGD PMID:21169467 PMID:21471098 RGD:5144151 RGD:5509920 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Lta lymphotoxin alpha susceptibility
no_association		 ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter		 RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373 NCBI chrNW_004936727:1,940,081...1,941,022
Ensembl chrNW_004936727:1,940,081...1,941,022 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chrNW_004936694:970,706...980,605 JBrowse link
G Mif macrophage migration inhibitory factor severity ISO DNA:repeats:promoter
DNA:SNP:promoter:rs755622(human)
protein:increased expression:bronchoalveolar lavage fluid		 RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059 NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857 		JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004936551:5,188,395...5,197,477 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung
protein:increased expression:serum		 RGD
CTD		 PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793 		JBrowse link
G Mpo myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum		 RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNP: : -109C>T (human)		 RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chrNW_004936581:2,743,133...2,751,925
Ensembl chrNW_004936581:2,744,881...2,751,925 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chrNW_004936580:4,691,870...4,694,092 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chrNW_004936816:60,499...91,628
Ensembl chrNW_004936816:60,499...91,628 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment ISO mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chrNW_004936816:129,926...159,396 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11587997 PMID:11802783 RGD:5131252 RGD:7364763 NCBI chrNW_004936816:174,943...209,241 JBrowse link
G Muc7 mucin 7, secreted ISO ClinVar Annotator: match by term: Asthma, protection against ClinVar
OMIM		 PMID:11378823 PMID:16759176 PMID:28492532
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004936560:2,797,943...2,828,813
Ensembl chrNW_004936560:2,796,697...2,829,650 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372 		JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chrNW_004936725:1,418,930...1,594,697
Ensembl chrNW_004936725:1,424,130...1,592,840 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262 		JBrowse link
G Ngf nerve growth factor severity ISO protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum		 RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chrNW_004936627:635,784...641,290
Ensembl chrNW_004936627:635,788...645,364 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chrNW_004936490:12,038,500...12,057,257
Ensembl chrNW_004936490:12,035,769...12,057,263 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:		 RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chrNW_004936478:6,717,354...6,768,293
Ensembl chrNW_004936478:6,715,245...6,768,372 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982 		JBrowse link
G Nos1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:exon
DNA:repeats:intron
DNA:repeats: :		 RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chrNW_004936558:5,162,471...5,302,488
Ensembl chrNW_004936558:5,233,459...5,301,414 		JBrowse link
G Nos2 nitric oxide synthase 2 severity
no_association
disease_progression		 ISO associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:SNP:exon:p.S608L (human)
DNA:repeat:promoter
protein:increased expression:lung, bronchoalveolar lavage fluid
DNA:repeats:promoter
protein:increased expression, increased activity:lung (rat)
CTD Direct Evidence: marker/mechanism
DNA:repeats:promoter, introns (human)
mRNA:increased expression:monocyte		 RGD
CTD		 PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)		 RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534 		JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 OMIM
ClinVar		 PMID:15073379 NCBI chrNW_004936478:10,352,894...10,542,949
Ensembl chrNW_004936478:10,352,741...10,544,102 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chrNW_004936478:1,289,437...1,296,819
Ensembl chrNW_004936478:1,290,505...1,296,874 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c. 609C>T (human)
DNA:SNP:exon:c.609C>T (human)		 CTD
RGD		 PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 severity
treatment
susceptibility		 ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron		 RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 More... RGD:408364991 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856 		JBrowse link
G Ntf3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chrNW_004936709:2,163,510...2,223,429
Ensembl chrNW_004936709:2,163,334...2,223,552 		JBrowse link
G Ntf4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chrNW_004936664:3,017,108...3,017,955 JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:16708804 PMID:20934630 RGD:5684766 RGD:5684772 NCBI chrNW_004936580:6,002,168...6,021,690
Ensembl chrNW_004936580:6,002,120...6,021,709 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chrNW_004936490:15,069,435...15,076,112
Ensembl chrNW_004936490:15,069,387...15,076,253 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 treatment ISO protein:increased activation:lung, blood, mononuclear cell
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642 		JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004936591:5,152,491...5,666,728
Ensembl chrNW_004936591:5,152,441...5,573,129 		JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chrNW_004936659:309,530...321,294
Ensembl chrNW_004936659:309,506...321,334 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chrNW_004936481:3,559,377...3,689,797
Ensembl chrNW_004936481:3,559,358...3,689,833 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10733466 RGD:1581025 NCBI chrNW_004936476:13,609,847...13,646,174
Ensembl chrNW_004936476:13,609,374...13,649,998 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18519237 PMID:21912604 RGD:4892037 NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chrNW_004936647:1,031,118...1,055,961
Ensembl chrNW_004936647:1,031,119...1,055,149 		JBrowse link
G Prf1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chrNW_004936521:8,057,874...8,060,695
Ensembl chrNW_004936521:8,057,874...8,060,695 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein severity
disease_progression
no_association		 ISO mRNA:increased expression:eosinophil:
associated with viral infection;mRNA:increased expression:sputum:
associated with cough;protein:increased expression:sputum:		 RGD PMID:11067904 PMID:16982448 PMID:22022864 PMID:24450586 RGD:13506941 RGD:13506942 RGD:13506943 RGD:13506944 NCBI chrNW_004936581:5,101,041...5,103,175
Ensembl chrNW_004936581:5,100,623...5,102,857 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004936664:3,492,032...3,502,738
Ensembl chrNW_004936664:3,491,920...3,504,667 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004936778:12,988...31,217
Ensembl chrNW_004936778:12,967...29,077 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004936654:1,336,546...1,464,959
Ensembl chrNW_004936654:1,336,429...1,461,476 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004936722:1,379,515...1,388,538
Ensembl chrNW_004936722:1,379,515...1,388,546 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chrNW_004936469:43,841,989...43,850,322
Ensembl chrNW_004936469:43,841,989...43,850,304 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323 		JBrowse link
G Ptgdr prostaglandin D2 receptor susceptibility ISO OMIM NCBI chrNW_004936697:2,481,340...2,488,868
Ensembl chrNW_004936697:2,481,340...2,488,868 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: therapeutic
Aspirin exacerbated asthma		 RGD
CTD		 PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chrNW_004936581:2,069,355...2,072,535
Ensembl chrNW_004936581:2,067,546...2,070,893 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity		 ISO DNA:SNP: :8473T>C (human)
mRNA:increased expression:lung
DNA:SNP: :rs689465 (human)
mRNA, protein:increased expression:lung:		 RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004936647:2,546,100...2,637,524
Ensembl chrNW_004936647:2,543,599...2,637,846 		JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chrNW_004936529:1,000,050...1,045,655
Ensembl chrNW_004936529:999,935...1,045,681 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chrNW_004936500:7,621,328...7,710,909
Ensembl chrNW_004936500:7,486,954...7,709,504 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO OMIM:600807 MouseDO NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to		 RGD
ClinVar		 PMID:9550363 PMID:9643286 PMID:12100044 PMID:21255142 RGD:5144226 NCBI chrNW_004936581:798,738...801,614
Ensembl chrNW_004936581:798,739...801,633 		JBrowse link
G Scgb3a2 secretoglobin family 3A member 2 susceptibility
severity
no_association		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)		 OMIM
ClinVar
RGD		 PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chrNW_004936504:6,933,641...6,936,838
Ensembl chrNW_004936504:6,933,769...6,936,838 		JBrowse link
G Sell selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chrNW_004936481:17,022,421...17,032,105
Ensembl chrNW_004936481:17,022,580...17,032,124 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility
severity
no_association		 ISO DNA:polymorphism:promoter:rs1799768 (human)
protein:increased expression:plasma
protein:increased activity, increased expression:plasma, lung		 RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chrNW_004936543:1,032,543...1,040,956
Ensembl chrNW_004936543:1,032,794...1,039,123 		JBrowse link
G Sftpb surfactant protein B ISO protein:increased expression:lung
protein:decreased expression:lung, Clara cell
mRNA, protein:decreased expression:lung		 RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466 		JBrowse link
G Sftpc surfactant protein C susceptibility ISO DNA:polymorphism: :p.A53T (human)
mRNA, protein:decreased expression:lung
protein:increased expression:lung		 RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011 		JBrowse link
G Sftpd surfactant protein D ISO associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung		 RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chrNW_004936569:888,309...895,991
Ensembl chrNW_004936569:887,742...895,977 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chrNW_004936728:703,688...706,317
Ensembl chrNW_004936728:704,290...705,885 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chrNW_004936729:1,511,648...1,534,042
Ensembl chrNW_004936729:1,511,836...1,536,200 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chrNW_004936538:6,205,268...6,239,062
Ensembl chrNW_004936538:6,205,251...6,239,083 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chrNW_004936500:10,345,154...10,352,873
Ensembl chrNW_004936500:10,345,154...10,352,867 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18211752 PMID:28807506 RGD:2317290 NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:16083555 PMID:19087723 RGD:7244151 RGD:7244153 NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157 		JBrowse link
G Tac1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chrNW_004936585:2,932,783...2,941,141
Ensembl chrNW_004936585:2,932,727...2,941,384 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chrNW_004936556:1,266,621...1,421,271
Ensembl chrNW_004936556:1,266,613...1,421,275 		JBrowse link
G Tacr2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chrNW_004936521:9,053,179...9,065,790
Ensembl chrNW_004936521:9,053,179...9,065,797 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chrNW_004936476:25,899,514...25,907,690
Ensembl chrNW_004936476:25,899,339...25,907,695 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism
OMIM:600807		 CTD
MouseDO		 PMID:15806396 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635 		JBrowse link
G Tbxa2r thromboxane A2 receptor severity
susceptibility		 ISO DNA:polymorphism:cds:924T>C(human)
ClinVar Annotator: match by term: Asthma		 RGD
ClinVar		 PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:12000493 More... RGD:11059534 RGD:11059535 NCBI chrNW_004936588:2,040,712...2,044,635
Ensembl chrNW_004936588:2,040,630...2,045,110 		JBrowse link
G Tgfb1 transforming growth factor beta 1 no_association
onset		 ISO DNA:polymorphism: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :multiple (human)
DNA:SNP:cds:915G>C (human)
mRNA:increased expression:lung
protein:increased expression:serum
DNA:SNP: :-509C>T (human)
DNA:SNPs:promoter, exon:multiple (human)		 RGD
CTD		 PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004936492:6,996,627...7,046,137
Ensembl chrNW_004936492:6,996,613...7,046,190 		JBrowse link
G Tlr1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004936482:6,582,430...6,591,128
Ensembl chrNW_004936482:6,582,584...6,584,971 		JBrowse link
G Tlr10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004936482:6,562,396...6,565,003 JBrowse link
G Tlr2 toll like receptor 2 susceptibility
severity		 ISO DNA:SNP: :rs3804100 (human)
DNA:SNP: :rs4696480 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)		 RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788 		JBrowse link
G Tlr3 toll like receptor 3 no_association ISO DNA:snp:cds:p.L412F (human)
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)		 RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907 		JBrowse link
G Tlr4 toll like receptor 4 severity
susceptibility
no_association		 ISO DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
DNA:Polymorphism:cds:p.D299G (human)
DNA:SNPs::
DNA:SNPs: :rs10983755, rs1927914 (human)
protein:decreased expression:leukocytes, mononuclear		 RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095 		JBrowse link
G Tlr6 toll like receptor 6 susceptibility ISO DNA:SNP: :p.S249P (human)
DNA:SNP (human)		 RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chrNW_004936482:6,607,723...6,610,161
Ensembl chrNW_004936482:6,607,753...6,610,143 		JBrowse link
G Tnc tenascin C ISO DNA:SNPs: :multiple (human)
DNA:SNP:exon:p.L1677I (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchus basement membrane		 RGD
CTD		 PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chrNW_004936487:4,172,263...4,256,780
Ensembl chrNW_004936487:4,172,886...4,233,126 		JBrowse link
G Tnf tumor necrosis factor no_association
susceptibility		 ISO DNA:polymorphism:promoter:
ClinVar Annotator: match by term: Asthma, susceptibility to		 RGD
OMIM
ClinVar		 PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143254 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chrNW_004936647:3,914,887...3,959,698
Ensembl chrNW_004936647:3,914,887...3,959,672 		JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization		 CTD
RGD		 PMID:19458046 PMID:31969645 RGD:127285811 NCBI chrNW_004936648:1,094,460...1,141,394
Ensembl chrNW_004936648:1,094,460...1,141,394 		JBrowse link
G Tslp thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chrNW_004936531:5,495,872...5,500,462 JBrowse link
G Ucn urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chrNW_004936493:5,258,574...5,260,692
Ensembl chrNW_004936493:5,260,219...5,260,602 		JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chrNW_004936623:2,339,259...2,345,717
Ensembl chrNW_004936623:2,340,778...2,345,700 		JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs: :multiple (human)
DNA:SNPs (human)
DNA:SNP (human)
DNA:SNP: :rs7975232 (human)		 RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:sputum		 CTD
RGD		 PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673 		JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chrNW_004936489:5,425,778...5,434,483
Ensembl chrNW_004936489:5,425,726...5,434,785 		JBrowse link
G Wdr36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004936531:5,513,082...5,546,515
Ensembl chrNW_004936531:5,513,082...5,548,501 		JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101964975 interleukin-8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353 		JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chrNW_004936543:2,414,948...2,416,922
Ensembl chrNW_004936543:2,414,850...2,416,953 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chrNW_004936547:479,261...504,757 JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chrNW_004936490:4,876,857...4,887,275
Ensembl chrNW_004936490:4,876,877...4,887,275 		JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chrNW_004936722:997,476...1,000,881
Ensembl chrNW_004936722:996,960...1,003,201 		JBrowse link
G LOC101958908 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907 		JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 RGD:126928124 NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647 		JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chrNW_004936994:158,621...171,597
Ensembl chrNW_004936994:158,620...171,601 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20022477 PMID:20485159 RGD:4145619 NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chrNW_004936547:479,261...504,757 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)		 CTD
RGD		 PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chrNW_004936565:1,917,970...1,919,027 JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chrNW_004936626:3,980,311...4,147,042
Ensembl chrNW_004936626:3,982,647...4,159,976 		JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chrNW_004936739:975,494...978,426
Ensembl chrNW_004936739:975,493...978,482 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936581:2,743,133...2,751,925
Ensembl chrNW_004936581:2,744,881...2,751,925 		JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chrNW_004936472:31,644,778...31,677,572
Ensembl chrNW_004936472:31,644,778...31,677,572 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936581:2,069,355...2,072,535
Ensembl chrNW_004936581:2,067,546...2,070,893 		JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chrNW_004936697:2,440,943...2,453,897
Ensembl chrNW_004936697:2,440,901...2,453,975 		JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936664:487,069...489,328
Ensembl chrNW_004936664:487,125...489,414 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mast cell		 CTD
RGD		 PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :795T>C (human)		 CTD
RGD		 PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chrNW_004936588:2,040,712...2,044,635
Ensembl chrNW_004936588:2,040,630...2,045,110 		JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chrNW_004936727:540,225...544,968
Ensembl chrNW_004936727:540,217...545,036 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635 		JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:25741868 PMID:30643255 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chrNW_004936739:975,494...978,426
Ensembl chrNW_004936739:975,493...978,482 		JBrowse link
G Ptger2 prostaglandin E receptor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chrNW_004936697:2,440,943...2,453,897
Ensembl chrNW_004936697:2,440,901...2,453,975 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar
OMIM		 PMID:25741868 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635 		JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612 		JBrowse link
chronic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngf nerve growth factor treatment ISO RGD PMID:30681402 RGD:405100716 NCBI chrNW_004936627:635,784...641,290
Ensembl chrNW_004936627:635,788...645,364 		JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 severity ISO protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chrNW_004936543:2,414,948...2,416,922
Ensembl chrNW_004936543:2,414,850...2,416,953 		JBrowse link
G Epx eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chrNW_004936490:4,876,857...4,887,275
Ensembl chrNW_004936490:4,876,877...4,887,275 		JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chrNW_004936556:1,266,621...1,421,271
Ensembl chrNW_004936556:1,266,613...1,421,275 		JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chrNW_004936569:4,774,602...4,842,906
Ensembl chrNW_004936569:4,774,542...4,844,494 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Cd86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chrNW_004936536:8,414,491...8,481,712 JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Il23a interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chrNW_004936646:743,630...745,998
Ensembl chrNW_004936646:743,688...745,836 		JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147 		JBrowse link
G Cdh17 cadherin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004936544:7,156,213...7,208,392
Ensembl chrNW_004936544:7,156,213...7,205,127 		JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004936471:38,419,147...38,606,312
Ensembl chrNW_004936471:38,419,129...38,606,323 		JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145 		JBrowse link
G LOC101963482 HLA class II histocompatibility antigen, DO alpha chain treatment ISO DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004936476:25,786,322...25,790,881
Ensembl chrNW_004936476:25,787,492...25,790,950 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004936481:3,559,377...3,689,797
Ensembl chrNW_004936481:3,559,358...3,689,833 		JBrowse link
G Prkca protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004936541:6,231,604...6,488,201
Ensembl chrNW_004936541:6,233,110...6,488,052 		JBrowse link
G Prkd1 protein kinase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004936494:4,469,092...4,601,183
Ensembl chrNW_004936494:4,469,089...4,601,214 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Tenm3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004936554:6,180,883...6,871,178
Ensembl chrNW_004936554:6,183,722...6,619,982 		JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII ISO ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency ClinVar
OMIM		 PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chrNW_004936476:13,609,847...13,646,174
Ensembl chrNW_004936476:13,609,374...13,649,998 		JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chrNW_004936647:2,647,982...2,651,477
Ensembl chrNW_004936647:2,648,241...2,651,430 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14615
    disease of anatomical entity 14320
      respiratory system disease 4634
        respiratory allergy 353
          asthma 319
            Asthma and Nasal Polyps 2
            Asthma, Short Stature, and Elevated IgA 0
            Eosinophilic Asthma 2
            Platelet-Activating Factor Acetylhydrolase Deficiency 1
            acute asthma + 5
            atopic dermatitis 3 0
            chronic asthma + 44
Path 2
Term Annotations click to browse term
  disease 14615
    disease of anatomical entity 14320
      Immune & Inflammatory Diseases 4904
        immune system disease 4357
          allergic disease 552
            Immediate Hypersensitivity 428
              respiratory allergy 353
                asthma 319
                  Asthma and Nasal Polyps 2
                  Asthma, Short Stature, and Elevated IgA 0
                  Eosinophilic Asthma 2
                  Platelet-Activating Factor Acetylhydrolase Deficiency 1
                  acute asthma + 5
                  atopic dermatitis 3 0
                  chronic asthma + 44
paths to the root