Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:asthma
go back to main search page
Accession:DOID:2841 term browser browse the term
Definition:A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Synonyms:exact_synonym: AS1;   asthmas;   bronchial asthma
 narrow_synonym: ASTHMA, DIMINISHED RESPONSE TO ANTILEUKOTRIENE TREATMENT IN;   adult onset asthma;   airway hyperresponsiveness
 related_synonym: ASRT1;   ASRT2;   ASRT3;   ASRT4;   ASRT5;   ASRT6;   ASRT7;   ASRT8;   Asthma-Related Traits, Susceptibility To, 1;   Asthma-Related Traits, Susceptibility To, 2;   Asthma-Related Traits, Susceptibility To, 3;   Asthma-Related Traits, Susceptibility To, 4;   Asthma-Related Traits, Susceptibility To, 5;   Asthma-Related Traits, Susceptibility To, 6;   Asthma-Related Traits, Susceptibility To, 7;   Asthma-Related Traits, Susceptibility To, 8;   allergic airway inflammation;   asthma and allergic rhinitis, susceptibility to;   asthma and atopy, susceptibility to;   asthma, protection against;   asthma, susceptibility to;   asthma-traits, susceptibility to asthma, protection against;   beta-2-adrenoreceptor agonist, reduced response to;   childhood athma, susceptibility to;   rhinoconjunctivitis, susceptibility to
 primary_id: MESH:D001249
 alt_id: MIM:600807;   MIM:601690;   MIM:607277;   MIM:608584;   MIM:609958;   MIM:610906;   MIM:611064;   MIM:611403;   MIM:611960;   MIM:613207
 xref: EFO:0000270;   EFO:0005414;   EFO:1002011;   GARD:10246;   ICD10CM:J45;   ICD9CM:493;   MONDO:0004979;   NCI:C28397
For additional species annotation, visit the Alliance of Genome Resources.


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:18931056 RGD:5128825 NCBI chrNW_004624782:449,217...590,306
Ensembl chrNW_004624782:449,288...591,310
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19383228 PMID:19484664 RGD:4140913 RGD:4140919 NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
JBrowse link
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chrNW_004624823:2,323,939...2,387,213
Ensembl chrNW_004624823:2,324,345...2,381,420
JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883
JBrowse link
G Adam33 ADAM metallopeptidase domain 33 no_association
susceptibility
disease_progression
ISO DNA:SNPs (human)
mRNA:increased expression:lung
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
DNA:SNPs: :multiple (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :p.M764T (human)
RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chrNW_004624741:4,764,508...4,778,174
Ensembl chrNW_004624741:4,766,306...4,775,501
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 NCBI chrNW_004624737:13,459,274...13,474,686 JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004624751:5,004,186...5,409,891
Ensembl chrNW_004624751:5,004,263...5,413,994
JBrowse link
G Adcyap1r1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chrNW_004624783:271,179...323,785
Ensembl chrNW_004624783:279,745...323,772
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO DNA:SNPs: :rs1154404, rs28730619 (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128882 RGD:5128890 RGD:5128891 RGD:5128892 NCBI chrNW_004625024:32,237...60,983
Ensembl chrNW_004625024:32,348...63,242
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
JBrowse link
G Adora1 adenosine A1 receptor ISO DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus
RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chrNW_004624807:7,674,164...7,705,736
Ensembl chrNW_004624807:7,674,927...7,705,051
JBrowse link
G Adora2a adenosine A2a receptor ISO DNA:SNP (human)
mRNA:decreased expression:aorta
RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chrNW_004624747:9,846,254...9,860,938
Ensembl chrNW_004624747:9,851,153...9,860,094
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :-1023A>G (human)
ClinVar
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:19638684 RGD:4145081 NCBI chrNW_004624774:8,211,723...8,215,962
Ensembl chrNW_004624774:8,211,984...8,213,240
JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment
onset
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
RGD
CTD
PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chrNW_004624754:24,138,086...24,140,900 JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:17877756 PMID:19080339 RGD:5147452 RGD:5147457 NCBI chrNW_004624730:25,964,848...26,006,468
Ensembl chrNW_004624730:25,964,811...26,006,463
JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chrNW_004624967:327,627...332,000
Ensembl chrNW_004624967:329,284...330,372
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690
JBrowse link
G Alox5 arachidonate 5-lipoxygenase treatment
no_association
severity
ISO DNA:polymorphism:promoter (human)
DNA:repeat:promoter (human)
RGD
OMIM
PMID:10369259 PMID:12911785 PMID:16364163 PMID:20128419 RGD:4890407 RGD:4890415 RGD:5147465 RGD:734557 NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility
no_association
ISO DNA:SNPs (human)
mRNA:increased expression:blood, leukocyte
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:repeat:promoter:-169(A)21 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
DNA:polymorphism:promoter (human)
DNA:SNP: :rs10507391 (human)
protein:increased expression:lung
RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chrNW_004624776:7,475,269...7,646,805
Ensembl chrNW_004624776:7,475,200...7,506,283
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chrNW_004624760:21,047,576...21,064,698
Ensembl chrNW_004624760:21,047,303...21,068,076
JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chrNW_004624811:765,338...782,203
Ensembl chrNW_004624811:764,940...782,198
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chrNW_004624730:1,290,692...1,299,365
Ensembl chrNW_004624730:1,290,655...1,299,410
JBrowse link
G Arg1 arginase 1 ISO mRNA, protein:increased expression:lung, mononuclear cell (human)
DNA:SNP: :rs2781667 (human)
mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12813022 PMID:19281908 PMID:19800904 PMID:20124949 RGD:4143187 RGD:5129205 NCBI chrNW_004624753:5,737,720...5,749,313
Ensembl chrNW_004624753:5,737,237...5,752,966
JBrowse link
G Arg2 arginase 2 severity
susceptibility
ISO mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3742879, rs17249437 (human)
DNA:SNPs (human)
RGD
CTD
PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chrNW_004624734:33,321,161...33,352,306
Ensembl chrNW_004624734:33,321,295...33,352,277
JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
JBrowse link
G Bdkrb2 bradykinin receptor B2 onset ISO DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil
RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chrNW_004624734:8,513,601...8,538,838
Ensembl chrNW_004624734:8,513,814...8,539,036
JBrowse link
G Bdnf brain derived neurotrophic factor severity
susceptibility
ISO DNA:polymorphisms: :p.V66M (rs6265) (human)
protein:decreased expression:blood, eosinophil
protein:increased expression:plasma
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chrNW_004624766:17,281,882...17,330,601
Ensembl chrNW_004624766:17,279,630...17,330,490
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chrNW_004624885:1,526,625...1,528,235
Ensembl chrNW_004624885:1,527,538...1,528,109
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004624757:22,697,639...23,142,209
Ensembl chrNW_004624757:22,955,666...23,142,499
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004624765:13,849,689...13,950,839
Ensembl chrNW_004624765:13,857,062...13,947,683
JBrowse link
G C3 complement C3 severity ISO protein:increased expression:serum
DNA:SNPs: :multiple (human)
DNA:SNP:intron:rs11569562 (human)
Interaction with IL4RA
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :4896C>T (human)
RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946
JBrowse link
G C3ar1 complement C3a receptor 1 severity ISO protein:increased expression:lung, leukocyte
mRNA:increased expression:lung
RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chrNW_004624860:5,196,621...5,204,686
Ensembl chrNW_004624860:5,197,619...5,199,043
JBrowse link
G C5ar1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394
JBrowse link
G Card11 caspase recruitment domain family member 11 susceptibility ISO ClinVar Annotator: match by term: Asthma RGD
ClinVar
PMID:16751370 PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 More... RGD:11100037 NCBI chrNW_004624740:29,974,707...30,085,498
Ensembl chrNW_004624740:29,974,689...30,085,981
JBrowse link
G Carm1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004624828:2,833,011...2,872,281
Ensembl chrNW_004624828:2,832,769...2,871,167
JBrowse link
G Cat catalase severity ISO DNA:polymorphism:promoter:-21A>T (human)
protein:decreased activity
protein:increased expression:erythrocyte
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chrNW_004624767:12,680,940...12,715,468
Ensembl chrNW_004624767:12,680,953...12,715,739
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chrNW_004624875:2,224,784...2,229,465 JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung
RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chrNW_004624746:28,655,288...28,657,563
Ensembl chrNW_004624746:28,655,801...28,657,470
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chrNW_004624736:39,088,741...39,090,745
Ensembl chrNW_004624736:39,088,921...39,090,394
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chrNW_004624843:2,017,738...2,021,153 JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO mRNA:increased expression:lung
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10384142 PMID:15993846 PMID:18316417 PMID:18684970 RGD:2306304 RGD:4145489 RGD:4891474 RGD:4891475 NCBI chrNW_004624746:28,694,879...28,700,711
Ensembl chrNW_004624746:28,694,735...28,700,827
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 susceptibility ISO DNA:SNPs: :179T>C, 275C>T (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:plasma
DNA:SNP: :1265A>G (human)
RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chrNW_004624740:14,640,486...14,652,414
Ensembl chrNW_004624740:14,640,292...14,643,020
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chrNW_004624736:39,055,705...39,056,722
Ensembl chrNW_004624736:39,055,726...39,057,630
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chrNW_004624759:11,759,304...11,781,284
Ensembl chrNW_004624759:11,759,048...11,784,493
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chrNW_004624730:74,768,668...74,769,749
Ensembl chrNW_004624730:74,768,668...74,769,798
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004624788:10,965,226...10,974,215
Ensembl chrNW_004624788:10,966,207...10,971,180
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004624785:12,190,802...12,203,924 JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004624795:2,777,766...2,787,664
Ensembl chrNW_004624795:2,779,627...2,788,897
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004624731:1,634,460...1,635,629
Ensembl chrNW_004624731:1,634,562...1,635,629
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chrNW_004624730:74,989,725...74,991,400
Ensembl chrNW_004624730:74,990,318...74,996,239
JBrowse link
G Cd14 CD14 molecule severity
susceptibility
no_association
ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -260C>T (human)
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
RGD
CTD
PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
JBrowse link
G Cd274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814
JBrowse link
G Cd28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856
JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338
JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chrNW_004624731:28,630,540...28,655,297
Ensembl chrNW_004624731:28,630,446...28,651,994
JBrowse link
G Cd86 CD86 molecule treatment ISO protein:increased expression:blood, B cell (human)
protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712
JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chrNW_004624746:17,480,472...17,557,722
Ensembl chrNW_004624746:17,483,469...17,557,581
JBrowse link
G Cdhr3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004624739:23,629,235...23,693,267 JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chrNW_004624827:1,704,733...1,893,579 JBrowse link
G Chat choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chrNW_004624928:357,812...401,668
Ensembl chrNW_004624928:360,704...399,714
JBrowse link
G Chi3l1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar
PMID:18403759 NCBI chrNW_004624807:7,655,777...7,664,484
Ensembl chrNW_004624807:7,655,620...7,662,362
JBrowse link
G Chml CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chrNW_004624771:11,981,078...11,987,379 JBrowse link
G Chrm1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chrNW_004624926:1,326,851...1,335,477
Ensembl chrNW_004624926:1,326,866...1,330,805
JBrowse link
G Chrm2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chrNW_004624765:17,211,162...17,342,505
Ensembl chrNW_004624765:17,333,678...17,340,421
JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chrNW_004624775:10,948,075...11,427,898
Ensembl chrNW_004624775:10,949,983...10,951,755
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131
JBrowse link
G Clca1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chrNW_004624742:11,145,406...11,172,369
Ensembl chrNW_004624742:11,145,413...11,172,369
JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chrNW_004624730:14,500,379...14,522,047
Ensembl chrNW_004624730:14,489,585...14,522,042
JBrowse link
G Cma1 chymase 1 susceptibility
no_association
severity
ISO DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
protein:increased expression:lung epithelium, mast cell (human)
RGD PMID:15248847 PMID:15924217 PMID:20813890 RGD:1625396 RGD:1625397 RGD:5128804 NCBI chrNW_004624820:8,021,965...8,024,763
Ensembl chrNW_004624820:8,021,959...8,024,851
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chrNW_004624849:2,484,144...2,528,130
Ensembl chrNW_004624849:2,484,109...2,528,223
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chrNW_004624739:114,383...161,010
Ensembl chrNW_004624739:114,342...161,044
JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
JBrowse link
G Csf2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chrNW_004624733:40,039,127...40,041,294
Ensembl chrNW_004624733:40,039,414...40,041,294
JBrowse link
G Csf3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chrNW_004624795:3,162,999...3,167,248
Ensembl chrNW_004624795:3,163,009...3,166,594
JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 severity
no_association
treatment
ISO DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3087243 (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chrNW_004624754:285,469...2,182,218
Ensembl chrNW_004624754:285,857...2,034,582
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chrNW_004624746:28,677,956...28,688,638
Ensembl chrNW_004624746:28,677,709...28,689,122
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:polymorphisms: :p.V249I, p.T280M (human)
DNA:SNPs: :p.V249I, rs2669849 (human)
RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chrNW_004624731:1,705,953...1,719,452
Ensembl chrNW_004624731:1,706,043...1,719,452
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chrNW_004624733:11,455,166...11,463,086
Ensembl chrNW_004624733:11,455,047...11,463,176
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chrNW_004624757:14,995,649...15,009,771
Ensembl chrNW_004624757:14,995,716...15,011,893
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 severity
susceptibility
ISO protein:decreased expression:respiratory system fluid/secretion, T cell
DNA:SNP:intron:IVS1+234G>A (human)
RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chrNW_004624903:1,958,323...1,961,789
Ensembl chrNW_004624903:1,958,698...1,961,763
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 no_association
severity
ISO DNA:SNPs:promoter, exon:multiple (human)
mRNA, protein:increased expression:respiratory system mucosa
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16387808 PMID:16630147 More... RGD:4781449 RGD:4781742 RGD:4782072 RGD:4784257 RGD:4843543 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116 NCBI chrNW_004624836:2,556,269...2,597,008 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chrNW_004624748:6,040,564...6,043,454 JBrowse link
G Dcn decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chrNW_004624750:15,466,938...15,517,475
Ensembl chrNW_004624750:15,470,968...15,516,365
JBrowse link
G Defb1 defensin beta 1 susceptibility ISO DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
DNA:SNP: :-1816 T>C (human)
RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chrNW_004624861:4,710,687...4,718,867 JBrowse link
G Dnah5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004624751:10,799,102...11,110,180
Ensembl chrNW_004624751:10,799,892...11,050,403
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD
RGD
PMID:23196709 PMID:23423710 RGD:9588646 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711
JBrowse link
G Dpp10 dipeptidyl peptidase like 10 ISO DNA:SNP:exon (human)
protein:increased expression:bronchus
DNA:SNP: :rs10208402 (human)
DNA:SNPs (human)
RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chrNW_004624732:29,385,895...30,748,424
Ensembl chrNW_004624732:29,386,401...30,042,127
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chrNW_004624828:5,402,589...5,409,914
Ensembl chrNW_004624828:5,402,961...5,407,891
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD
RGD
PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chrNW_004624756:13,842,482...13,849,003
Ensembl chrNW_004624756:13,842,164...13,849,029
JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chrNW_004624853:6,298,406...6,362,353
Ensembl chrNW_004624853:6,302,751...6,360,089
JBrowse link
G Ednrb endothelin receptor type B ISO mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)
RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chrNW_004624751:22,459,613...22,491,409
Ensembl chrNW_004624751:22,459,584...22,491,606
JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (mouse)
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (rat)
RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chrNW_004624740:584,133...713,205
Ensembl chrNW_004624740:589,606...713,271
JBrowse link
G Egr1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)
RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chrNW_004624743:31,247,855...31,251,675
Ensembl chrNW_004624743:31,247,516...31,252,205
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chrNW_004624758:2,575,516...2,646,313
Ensembl chrNW_004624758:2,575,671...2,646,313
JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chrNW_004624835:6,161,930...6,181,016
Ensembl chrNW_004624835:6,162,111...6,168,714
JBrowse link
G Epx eosinophil peroxidase disease_progression
severity
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chrNW_004624871:40,811...50,436
Ensembl chrNW_004624871:40,885...50,116
JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chrNW_004624734:36,742,913...36,862,993
Ensembl chrNW_004624734:36,759,104...36,825,295
JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
RGD PMID:21658190 PMID:21711961 RGD:5147753 RGD:5147783 NCBI chrNW_004624767:1,876,974...1,887,720
Ensembl chrNW_004624767:1,877,024...1,887,958
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004624793:780,057...788,105
Ensembl chrNW_004624793:780,059...788,095
JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia severity ISO Fatal asthma subjects
Asthma symptoms persistent despite steroids
RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chrNW_004624794:2,003,031...2,008,930
Ensembl chrNW_004624794:2,002,928...2,008,940
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chrNW_004624826:23,930...34,735 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chrNW_004624826:51,387...59,117 JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004624858:5,848,817...5,856,448 JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chrNW_004624754:21,825,122...21,930,870
Ensembl chrNW_004624754:21,870,240...21,929,838
JBrowse link
G Foxp3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392
JBrowse link
G Gc GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chrNW_004624890:3,274,239...3,318,281
Ensembl chrNW_004624890:3,226,900...3,318,316
JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chrNW_004624772:5,495,452...5,498,714
Ensembl chrNW_004624772:5,495,452...5,498,652
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chrNW_004624733:32,284,793...32,310,980 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chrNW_004624856:4,834,197...4,861,546
Ensembl chrNW_004624856:4,834,217...4,861,592
JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chrNW_004624731:9,835,585...9,856,743
Ensembl chrNW_004624731:9,835,596...9,856,743
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chrNW_004624951:681,559...711,476
Ensembl chrNW_004624951:682,178...711,474
JBrowse link
G Hmox1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility
ISO ClinVar Annotator: match by term: Asthma, susceptibility to RGD
OMIM
ClinVar
PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 More... RGD:5128885 RGD:5128887 RGD:5128888 NCBI chrNW_004624732:37,621,014...37,689,873
Ensembl chrNW_004624732:37,620,925...37,691,708
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chrNW_004624746:18,883,587...18,889,205
Ensembl chrNW_004624746:18,883,353...18,889,402
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chrNW_004624748:8,154,288...8,223,226
Ensembl chrNW_004624748:8,155,107...8,223,259
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aorta (mouse)
protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)
CTD
RGD
PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071
JBrowse link
G Ifng interferon gamma resistance
treatment
ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chrNW_004624886:618,372...640,954
Ensembl chrNW_004624886:618,289...642,928
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chrNW_004624795:3,222,170...3,347,079
Ensembl chrNW_004624795:3,290,078...3,345,533
JBrowse link
G Il10 interleukin 10 susceptibility
treatment
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma
DNA:polymorphism: :-627C>A (human)
RGD
CTD
PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il12a interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940
JBrowse link
G Il12b interleukin 12B severity
susceptibility
ISO DNA:polymorphisms:introns:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphisms:promoter, 3'utr:
DNA:polymorphism:promoter
RGD
ClinVar
PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589
JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism:cds:p.R130Q (human)
protein:increased expression:serum
protein:increased expression:sputum
OMIM
ClinVar
RGD
PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chrNW_004624733:39,427,189...39,430,019
Ensembl chrNW_004624733:39,428,095...39,429,843
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 no_association ISO mRNA:increased expression:bronchus
DNA:polymorphism: :1050C>T (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1398A>G (human)
RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655 NCBI chrNW_004624895:2,706,225...2,763,489
Ensembl chrNW_004624895:2,706,043...2,763,798
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum
mRNA:increased expression:bronchus
RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chrNW_004624940:825,368...842,268
Ensembl chrNW_004624940:819,854...842,284
JBrowse link
G Il15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chrNW_004624853:1,059,625...1,144,799
Ensembl chrNW_004624853:1,128,519...1,144,941
JBrowse link
G Il16 interleukin 16 no_association
severity
ISO DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chrNW_004624768:20,597,560...20,704,437 JBrowse link
G Il17a interleukin 17A susceptibility ISO protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
JBrowse link
G Il17rb interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chrNW_004624822:3,339,236...3,355,278
Ensembl chrNW_004624822:3,337,940...3,355,199
JBrowse link
G Il18 interleukin 18 susceptibility
severity
disease_progression
ISO DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
protein:increased expression:serum
DNA:polymorphism: :c. -105A>C (human)
RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)
RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chrNW_004624749:6,875,934...6,909,702
Ensembl chrNW_004624749:6,875,750...6,909,734
JBrowse link
G Il19 interleukin 19 ISO protein:increased expression:serum
mRNA, protein:increased expression:lung, serum
RGD PMID:15557163 RGD:5037236 NCBI chrNW_004624807:4,636,357...4,641,022
Ensembl chrNW_004624807:4,636,374...4,641,022
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chrNW_004624749:12,795,967...12,805,658
Ensembl chrNW_004624749:12,795,946...12,805,154
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
RGD
CTD
PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Il1rl1 interleukin 1 receptor like 1 severity
susceptibility
ISO protein:increased expression:serum
DNA:SNP: :rs1420101 (human)
DNA:SNP: :rs1041973 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11463601 PMID:17407196 PMID:17623648 PMID:19179489 PMID:19198610 More... RGD:5144235 RGD:5144237 RGD:5144239 RGD:5144240 RGD:5144242 RGD:5144243 RGD:5144244 RGD:5144245 NCBI chrNW_004624749:6,795,822...6,873,068
Ensembl chrNW_004624749:6,795,748...6,873,701
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity
ISO DNA, protein:repeat, decreased expression (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA:SNPs: :multiple (human)
DNA:polymorphism:intron (human)
DNA:SNP: :rs2234678 (human)
RGD
CTD
PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890
JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304
JBrowse link
G Il22 interleukin 22 treatment
severity
ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell
RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chrNW_004624802:46,585...51,095
Ensembl chrNW_004624802:46,585...51,095
JBrowse link
G Il23r interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chrNW_004624742:27,899,934...27,954,145
Ensembl chrNW_004624742:27,901,071...27,941,109
JBrowse link
G Il25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chrNW_004624820:9,188,709...9,192,180
Ensembl chrNW_004624820:9,188,612...9,191,990
JBrowse link
G Il27 interleukin 27 treatment
susceptibility
ISO protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)
RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491 NCBI chrNW_004624782:13,009,450...13,015,548
Ensembl chrNW_004624782:13,009,564...13,015,440
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chrNW_004624901:1,274,753...1,288,783
Ensembl chrNW_004624901:1,274,840...1,287,861
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chrNW_004624775:927,337...991,062
Ensembl chrNW_004624775:924,648...942,354
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chrNW_004624752:10,662,053...10,682,891
Ensembl chrNW_004624752:10,672,432...10,683,045
JBrowse link
G Il33 interleukin 33 treatment
severity
ISO associated with viral pneumonia;
associated with fungal infectious disease
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
JBrowse link
G Il4 interleukin 4 no_association
treatment
ISO DNA:SNP: :589C>T (human)
DNA:polymorphism (human)
mRNA, protein:increase expression:leukocyte, serum
mRNA:increased expression:lung, spleen
CTD Direct Evidence: marker/mechanism
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:lung
RGD
CTD
PMID:18211752 PMID:18357729 PMID:20524005 PMID:21103062 PMID:21354484 More... RGD:10402791 RGD:10402799 RGD:2317290 RGD:4889866 RGD:5128500 RGD:5128502 RGD:5128557 RGD:5128560 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il4r interleukin 4 receptor susceptibility
severity
disease_progression
ISO protein:increased secretion:plasma
OMIM:600807
DNA:polymorphism::-1902G/A (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:mutation:cds:p.Q576R (mouse)
DNA:SNPs: :multiple
DNA:polymorphism:cds:p.Q551R (human)
DNA:polymorphism:cds:p.Q576R (human)
RGD
MouseDO
PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 NCBI chrNW_004624782:11,981,781...12,008,362 JBrowse link
G Il5 interleukin 5 treatment
disease_progression
ISO protein: increased levels: sputum
DNA:polymorphism:promoter:-703C>T (human)
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:lungs, respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chrNW_004624733:39,544,487...39,558,943
Ensembl chrNW_004624733:39,556,797...39,559,119
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)
RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chrNW_004624773:13,309,888...13,347,318
Ensembl chrNW_004624773:13,311,583...13,347,315
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
associated with Hypersensitivity;protein:increased expression:sputum
CTD
RGD
PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chrNW_004624885:2,910,367...2,946,916
Ensembl chrNW_004624885:2,910,112...2,946,886
JBrowse link
G Il9 interleukin 9 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chrNW_004624733:11,226,769...11,229,461
Ensembl chrNW_004624733:11,226,769...11,229,461
JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chrNW_004624913:906,953...918,906
Ensembl chrNW_004624913:908,644...920,658
JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar
PMID:17503328 NCBI chrNW_004624802:2,042,486...2,098,921
Ensembl chrNW_004624802:2,047,409...2,098,545
JBrowse link
G Irf1 interferon regulatory factor 1 no_association
susceptibility
ISO DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
DNA:repeat:intron (human)
protein:increased expression:respiratory tract epithelium
RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526
JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chrNW_004624832:4,611,445...4,616,319
Ensembl chrNW_004624832:4,612,374...4,616,276
JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chrNW_004624849:1,895,378...1,952,755
Ensembl chrNW_004624849:1,895,914...1,952,665
JBrowse link
G Itgb6 integrin subunit beta 6 ISO OMIM:600807 MouseDO NCBI chrNW_004624732:5,348,589...5,499,826
Ensembl chrNW_004624732:5,403,956...5,499,855
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chrNW_004624773:14,856,803...15,193,173
Ensembl chrNW_004624773:14,856,804...15,193,168
JBrowse link
G Kdr kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chrNW_004624761:14,330,224...14,380,680
Ensembl chrNW_004624761:14,330,489...14,379,051
JBrowse link
G Kif3a kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004624733:39,354,360...39,406,574
Ensembl chrNW_004624733:39,354,232...39,407,121
JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
JBrowse link
G Lgals3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637
JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :
DNA:haplotype
CTD
RGD
PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:13506911 RGD:5143938 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663
JBrowse link
G LOC101698463 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chrNW_004624754:23,674,935...23,683,044
Ensembl chrNW_004624754:23,674,448...23,683,662
JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain no_association
susceptibility
disease_progression
ISO CTD Direct Evidence: marker/mechanism
Alternaria sensitive asthma
DNA:polymorphisms: :
DNA:polymorphisms (human)
CTD
RGD
PMID:10792356 PMID:11802952 PMID:12890388 PMID:19052351 PMID:20159242 More... RGD:13506906 RGD:13506913 RGD:4144113 RGD:4144181 RGD:5147617 RGD:5147799 RGD:5147831 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713
JBrowse link
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512
JBrowse link
G LOC101707509 cytochrome P450 1A1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chrNW_004627988:7...1,323 JBrowse link
G LOC101717043 cytochrome b-245 light chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chrNW_004624746:911,852...919,361
Ensembl chrNW_004624746:911,842...919,362
JBrowse link
G LOC101722366 cytochrome P450 2E1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:leukocyte
CTD
RGD
PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
JBrowse link
G LOC101724812 C-C chemokine receptor type 1 severity ISO associated with Respiratory Syncytial Virus Infections
mRNA:increased expression:lung
RGD PMID:15593301 PMID:15654816 RGD:5688158 RGD:5688159 NCBI chrNW_004624730:74,822,848...74,828,614
Ensembl chrNW_004624730:74,826,659...74,827,726
JBrowse link
G Lta lymphotoxin alpha no_association
susceptibility
ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter
RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373 NCBI chrNW_004624754:24,626,930...24,628,412
Ensembl chrNW_004624754:24,627,318...24,628,182
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chrNW_004624750:11,274,506...11,314,683
Ensembl chrNW_004624750:11,274,664...11,314,581
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:12910828 RGD:8693709 NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297
JBrowse link
G Mefv MEFV innate immunity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chrNW_004624824:1,035,172...1,047,632
Ensembl chrNW_004624824:1,035,094...1,047,678
JBrowse link
G Mif macrophage migration inhibitory factor severity ISO protein:increased expression:bronchoalveolar lavage fluid
DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter
RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059 NCBI chrNW_004624747:10,307,826...10,308,649
Ensembl chrNW_004624747:10,303,919...10,308,821
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chrNW_004624878:71,642...79,660
Ensembl chrNW_004624878:71,642...79,602
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004624878:107,330...117,654
Ensembl chrNW_004624878:107,361...117,459
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:serum
mRNA, protein:increased expression:lung
DNA:SNP: : rs2664538(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chrNW_004624790:8,584,399...8,591,763
Ensembl chrNW_004624790:8,583,457...8,591,713
JBrowse link
G Mpo myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum
RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chrNW_004624871:121,026...131,433
Ensembl chrNW_004624871:121,026...131,323
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chrNW_004624864:804,950...813,419
Ensembl chrNW_004624864:807,253...813,381
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168
JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chrNW_004624885:2,339,281...2,343,351 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chrNW_004624766:21,493,125...21,522,535 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment ISO mRNA,protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chrNW_004624766:21,439,023...21,461,108 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11587997 PMID:11802783 RGD:5131252 RGD:7364763 NCBI chrNW_004624766:21,398,595...21,425,755 JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004624886:2,455,704...2,489,593 JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489
JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chrNW_004624912:1,952,053...2,213,196
Ensembl chrNW_004624912:1,953,838...2,172,561
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chrNW_004624787:14,355,330...14,381,353
Ensembl chrNW_004624787:14,355,791...14,381,251
JBrowse link
G Ngf nerve growth factor severity ISO protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum
RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chrNW_004624772:11,009,765...11,070,050
Ensembl chrNW_004624772:11,010,845...11,070,017
JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chrNW_004624795:5,623,686...5,639,545
Ensembl chrNW_004624795:5,623,700...5,639,655
JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:insertion:cds:
DNA:SNP: :rs2075817 (human)
RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chrNW_004624739:285,791...339,752
Ensembl chrNW_004624739:285,689...341,956
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Nos1 nitric oxide synthase 1 susceptibility ISO DNA:repeats: :
DNA:repeats:exon
DNA:repeats:intron
RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chrNW_004624747:15,940,614...16,118,051
Ensembl chrNW_004624747:16,003,969...16,113,165
JBrowse link
G Nos2 nitric oxide synthase 2 severity
disease_progression
no_association
ISO DNA:repeats:promoter, introns (human)
protein:increased expression:lung, bronchoalveolar lavage fluid
protein:increased expression, increased activity:lung (rat)
mRNA:increased expression:monocyte
DNA:repeat:promoter
DNA:SNP:exon:p.S608L (human)
CTD Direct Evidence: marker/mechanism
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
RGD
CTD
PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chrNW_004624786:491,944...530,427
Ensembl chrNW_004624786:489,311...528,271
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chrNW_004624800:5,600,215...5,619,020
Ensembl chrNW_004624800:5,600,212...5,619,004
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chrNW_004624739:6,277,704...6,285,454
Ensembl chrNW_004624739:6,277,612...6,285,397
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
DNA:SNP:exon:c.609C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chrNW_004624746:16,684,620...16,698,194
Ensembl chrNW_004624746:16,684,407...16,697,479
JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 treatment
severity
susceptibility
ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron
RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 More... RGD:408364991 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632
JBrowse link
G Ntf3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chrNW_004624860:2,416,448...2,479,216
Ensembl chrNW_004624860:2,416,503...2,479,225
JBrowse link
G Ntf4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chrNW_004624832:5,005,935...5,008,694
Ensembl chrNW_004624832:5,007,801...5,008,451
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:16708804 PMID:20934630 RGD:5684766 RGD:5684772 NCBI chrNW_004624885:1,989,027...2,005,474
Ensembl chrNW_004624885:1,989,138...2,005,577
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chrNW_004624730:28,771,020...28,819,179
Ensembl chrNW_004624730:28,772,525...28,782,431
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell
CTD
RGD
PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chrNW_004624807:446,662...478,571
Ensembl chrNW_004624807:446,647...479,069
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004624847:5,732,922...5,741,908
Ensembl chrNW_004624847:5,732,767...5,742,269
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004624742:28,557,159...29,113,269
Ensembl chrNW_004624742:28,557,283...29,016,844
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chrNW_004624752:9,072,471...9,088,289
Ensembl chrNW_004624752:9,072,512...9,088,593
JBrowse link
G Pgf placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chrNW_004624734:26,751,986...26,764,154
Ensembl chrNW_004624734:26,751,530...26,764,242
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chrNW_004624739:22,737,376...22,772,696
Ensembl chrNW_004624739:22,737,270...22,772,589
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chrNW_004624828:2,121,262...2,131,645
Ensembl chrNW_004624828:2,121,329...2,131,645
JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10733466 RGD:1581025 NCBI chrNW_004624754:13,905,084...13,932,366
Ensembl chrNW_004624754:13,904,797...13,931,670
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18519237 PMID:21912604 RGD:4892037 NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chrNW_004624733:38,012,694...38,033,745
Ensembl chrNW_004624733:38,012,392...38,036,914
JBrowse link
G Prf1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chrNW_004624754:4,679,451...4,681,627
Ensembl chrNW_004624754:4,679,521...4,681,627
JBrowse link
G Prmt1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004624832:4,593,594...4,602,514
Ensembl chrNW_004624832:4,589,743...4,602,402
JBrowse link
G Prmt2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004624745:31,680,149...31,701,322
Ensembl chrNW_004624745:31,689,868...31,709,018
JBrowse link
G Prmt3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004624766:11,669,732...11,797,133
Ensembl chrNW_004624766:11,670,108...11,795,272
JBrowse link
G Prmt5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004624820:9,599,867...9,608,578
Ensembl chrNW_004624820:9,599,734...9,608,703
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chrNW_004624732:13,915,361...13,922,182
Ensembl chrNW_004624732:13,915,402...13,923,593
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Ptgdr prostaglandin D2 receptor susceptibility ISO OMIM NCBI chrNW_004624731:16,776,050...16,785,178
Ensembl chrNW_004624731:16,777,678...16,785,130
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: therapeutic
Aspirin exacerbated asthma
CTD
RGD
PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chrNW_004624926:263,942...268,875 JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chrNW_004624742:25,177,340...25,356,911 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
mRNA:increased expression:lung
DNA:SNP: :rs689465 (human)
RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004624733:39,445,083...39,544,415
Ensembl chrNW_004624733:39,447,461...39,544,409
JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chrNW_004624730:3,316,122...3,361,820 JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chrNW_004624745:22,921,180...23,158,250
Ensembl chrNW_004624745:22,921,120...23,157,876
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO OMIM:600807 MouseDO NCBI chrNW_004624764:9,192,067...9,218,617
Ensembl chrNW_004624764:9,191,556...9,248,252
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
ClinVar
PMID:9550363 PMID:9643286 PMID:12100044 PMID:21255142 RGD:5144226 NCBI chrNW_004624926:1,029,120...1,030,250 JBrowse link
G Scgb3a2 secretoglobin family 3A member 2 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)
OMIM
ClinVar
RGD
PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chrNW_004624774:7,305,272...7,308,514
Ensembl chrNW_004624774:7,305,239...7,308,592
JBrowse link
G Sell selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chrNW_004624826:7,590,576...7,612,370
Ensembl chrNW_004624826:7,587,970...7,610,163
JBrowse link
G Serpine1 serpin family E member 1 severity
susceptibility
no_association
ISO protein:increased expression:plasma
protein:increased activity, increased expression:plasma, lung
DNA:polymorphism:promoter:rs1799768 (human)
RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337
JBrowse link
G Sftpb surfactant protein B ISO mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
protein:increased expression:lung
RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chrNW_004624749:17,486,483...17,495,822
Ensembl chrNW_004624749:17,486,518...17,493,846
JBrowse link
G Sftpc surfactant protein C susceptibility ISO protein:increased expression:lung
DNA:polymorphism: :p.A53T (human)
mRNA, protein:decreased expression:lung
RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chrNW_004624758:17,742,439...17,744,664
Ensembl chrNW_004624758:17,742,415...17,744,655
JBrowse link
G Sftpd surfactant protein D ISO mRNA, protein:increased expression:lung
associated with Bronchitis;protein:increased expression:lung
RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chrNW_004624841:6,917,067...6,938,594
Ensembl chrNW_004624841:6,916,849...6,936,077
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chrNW_004624823:6,612,452...6,625,047
Ensembl chrNW_004624823:6,612,452...6,625,300
JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chrNW_004624928:403,114...405,560
Ensembl chrNW_004624928:403,503...405,095
JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chrNW_004624749:11,347,602...11,371,113
Ensembl chrNW_004624749:11,347,609...11,371,330
JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chrNW_004624786:2,673,285...2,711,432
Ensembl chrNW_004624786:2,672,552...2,710,914
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chrNW_004624745:20,032,003...20,037,958
Ensembl chrNW_004624745:20,032,011...20,037,958
JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367
JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18211752 PMID:28807506 RGD:2317290 NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391
JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:16083555 PMID:19087723 RGD:7244151 RGD:7244153 NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693
JBrowse link
G Tac1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chrNW_004624813:4,542,226...4,550,378
Ensembl chrNW_004624813:4,542,011...4,550,486
JBrowse link
G Tacr1 tachykinin receptor 1 ISO protein:increased expression:lung
mRNA,protein:increased expression:lung
mRNA:increased expression:lung
RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chrNW_004624749:28,243,667...28,455,012
Ensembl chrNW_004624749:28,243,640...28,455,086
JBrowse link
G Tacr2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chrNW_004624754:3,658,128...3,670,432
Ensembl chrNW_004624754:3,656,319...3,670,432
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chrNW_004624754:23,815,464...23,822,480
Ensembl chrNW_004624754:23,815,915...23,822,827
JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism
OMIM:600807
CTD
MouseDO
PMID:15806396 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
G Tbxa2r thromboxane A2 receptor severity
susceptibility
ISO DNA:polymorphism:cds:924T>C(human)
ClinVar Annotator: match by term: Asthma
RGD
ClinVar
PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:12000493 More... RGD:11059534 RGD:11059535 NCBI chrNW_004624828:6,291,010...6,312,438
Ensembl chrNW_004624828:6,291,167...6,309,482
JBrowse link
G Tgfb1 transforming growth factor beta 1 no_association
onset
ISO DNA:SNPs:promoter, exon:multiple (human)
DNA:polymorphism: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :multiple (human)
mRNA:increased expression:lung
protein:increased expression:serum
DNA:SNP:cds:915G>C (human)
DNA:SNP: :-509C>T (human)
RGD
CTD
PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chrNW_004624741:22,880,481...22,883,962 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004624750:1,776,197...1,817,279
Ensembl chrNW_004624750:1,775,744...1,817,385
JBrowse link
G Tlr1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004624840:7,287,772...7,349,282
Ensembl chrNW_004624840:7,287,781...7,290,162
JBrowse link
G Tlr10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004624840:7,269,628...7,273,316 JBrowse link
G Tlr2 toll like receptor 2 susceptibility
severity
ISO DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)
DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs4696480 (human)
RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
JBrowse link
G Tlr3 toll like receptor 3 no_association ISO DNA:snp:cds:p.L412F (human)
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
JBrowse link
G Tlr4 toll like receptor 4 susceptibility
no_association
severity
ISO DNA:Polymorphism:cds:p.D299G (human)
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs::
RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link
G Tlr6 toll like receptor 6 susceptibility ISO DNA:SNP (human)
DNA:SNP: :p.S249P (human)
RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Tnc tenascin C ISO DNA:SNP:exon:p.L1677I (human)
protein:increased expression:bronchus basement membrane
DNA:SNPs: :multiple (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chrNW_004624760:20,044,900...20,137,260
Ensembl chrNW_004624760:20,044,826...20,137,616
JBrowse link
G Tnf tumor necrosis factor no_association
susceptibility
ISO DNA:polymorphism:promoter:
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
OMIM
ClinVar
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143254 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chrNW_004624860:3,111,244...3,123,041
Ensembl chrNW_004624860:3,111,630...3,122,711
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chrNW_004624733:40,964,020...41,006,381 JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chrNW_004624744:18,997,273...19,042,838
Ensembl chrNW_004624744:18,997,462...19,042,227
JBrowse link
G Ucn urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chrNW_004624738:9,393,004...9,393,966
Ensembl chrNW_004624738:9,393,329...9,393,706
JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs: :multiple (human)
DNA:SNPs (human)
DNA:SNP (human)
DNA:SNP: :rs7975232 (human)
RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chrNW_004624816:4,314,146...4,423,946
Ensembl chrNW_004624816:4,365,961...4,424,514
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chrNW_004624754:15,929,414...15,943,637 JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chrNW_004624785:5,466,429...5,487,763
Ensembl chrNW_004624785:5,468,563...5,488,143
JBrowse link
G Wdr36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004624743:28,903,013...28,944,353
Ensembl chrNW_004624743:28,903,093...28,942,978
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chrNW_004624836:2,556,269...2,597,008 JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chrNW_004624871:40,811...50,436
Ensembl chrNW_004624871:40,885...50,116
JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chrNW_004624820:9,188,709...9,192,180
Ensembl chrNW_004624820:9,188,612...9,191,990
JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663
JBrowse link
G LOC101698463 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004624754:23,674,935...23,683,044
Ensembl chrNW_004624754:23,674,448...23,683,662
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chrNW_004624832:2,491,372...2,500,622
Ensembl chrNW_004624832:2,491,281...2,500,653
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20022477 PMID:20485159 RGD:4145619 NCBI chrNW_004624730:74,768,668...74,769,749
Ensembl chrNW_004624730:74,768,668...74,769,798
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chrNW_004624836:2,556,269...2,597,008 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chrNW_004624748:6,040,564...6,043,454 JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chrNW_004624753:16,566,864...16,811,438 JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663
JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713
JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chrNW_004624733:42,668,963...42,673,385
Ensembl chrNW_004624733:42,670,632...42,672,846
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004624864:804,950...813,419
Ensembl chrNW_004624864:807,253...813,381
JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chrNW_004624920:542,479...575,760
Ensembl chrNW_004624920:540,750...575,855
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004624926:263,942...268,875 JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chrNW_004624731:16,729,846...16,741,529
Ensembl chrNW_004624731:16,726,975...16,741,557
JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004624832:6,948,638...6,952,664
Ensembl chrNW_004624832:6,948,572...6,952,719
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chrNW_004624754:23,827,782...23,845,690
Ensembl chrNW_004624754:23,827,706...23,837,356
JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chrNW_004624828:6,291,010...6,312,438
Ensembl chrNW_004624828:6,291,167...6,309,482
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512
JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ltc4s leukotriene C4 synthase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chrNW_004624733:42,668,963...42,673,385
Ensembl chrNW_004624733:42,670,632...42,672,846
JBrowse link
G Ptger2 prostaglandin E receptor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chrNW_004624731:16,729,846...16,741,529
Ensembl chrNW_004624731:16,726,975...16,741,557
JBrowse link
G Tbx21 T-box transcription factor 21 susceptibility ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar
OMIM
PMID:25741868 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205
JBrowse link
chronic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngf nerve growth factor treatment ISO RGD PMID:30681402 RGD:405100716 NCBI chrNW_004624772:11,009,765...11,070,050
Ensembl chrNW_004624772:11,010,845...11,070,017
JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epx eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chrNW_004624871:40,811...50,436
Ensembl chrNW_004624871:40,885...50,116
JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chrNW_004624749:28,243,667...28,455,012
Ensembl chrNW_004624749:28,243,640...28,455,086
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chrNW_004624823:2,323,939...2,387,213
Ensembl chrNW_004624823:2,324,345...2,381,420
JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
JBrowse link
G Cd86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712
JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004624771:9,031,978...9,038,760
Ensembl chrNW_004624771:9,032,016...9,038,825
JBrowse link
G Il23a interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418
JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chrNW_004624754:24,138,086...24,140,900 JBrowse link
G Cdh17 cadherin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004624763:1,543,341...1,621,970
Ensembl chrNW_004624763:1,543,048...1,621,978
JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663
JBrowse link
G LOC101698840 HLA class II histocompatibility antigen, DO alpha chain treatment ISO DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004624754:23,725,903...23,729,446
Ensembl chrNW_004624754:23,725,986...23,727,765
JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286
JBrowse link
G Prkca protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004624870:1,589,775...2,023,160
Ensembl chrNW_004624870:1,596,102...2,023,172
JBrowse link
G Prkd1 protein kinase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004624820:2,408,562...2,726,199
Ensembl chrNW_004624820:2,408,360...2,726,606
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004624760:12,917,244...12,937,858
Ensembl chrNW_004624760:12,915,206...12,937,824
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
JBrowse link
G Tenm3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004624769:12,831,899...13,579,957
Ensembl chrNW_004624769:13,104,585...13,579,136
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII ISO ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency ClinVar
OMIM
PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chrNW_004624754:13,905,084...13,932,366
Ensembl chrNW_004624754:13,904,797...13,931,670
JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Il5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chrNW_004624733:39,544,487...39,558,943
Ensembl chrNW_004624733:39,556,797...39,559,119
JBrowse link
G Mpo myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chrNW_004624871:121,026...131,433
Ensembl chrNW_004624871:121,026...131,323
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14208
    disease of anatomical entity 13924
      respiratory system disease 4527
        respiratory allergy 331
          asthma 299
            Asthma and Nasal Polyps 2
            Asthma, Short Stature, and Elevated IgA 0
            Eosinophilic Asthma 1
            Platelet-Activating Factor Acetylhydrolase Deficiency 1
            acute asthma + 5
            atopic dermatitis 3 0
            chronic asthma + 42
Path 2
Term Annotations click to browse term
  disease 14208
    disease of anatomical entity 13924
      Immune & Inflammatory Diseases 4781
        immune system disease 4247
          allergic disease 528
            Immediate Hypersensitivity 404
              respiratory allergy 331
                asthma 299
                  Asthma and Nasal Polyps 2
                  Asthma, Short Stature, and Elevated IgA 0
                  Eosinophilic Asthma 1
                  Platelet-Activating Factor Acetylhydrolase Deficiency 1
                  acute asthma + 5
                  atopic dermatitis 3 0
                  chronic asthma + 42
paths to the root