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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:asthma
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Accession:DOID:2841 term browser browse the term
Definition:A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Synonyms:exact_synonym: AS1;   asthmas;   bronchial asthma
 narrow_synonym: ASTHMA, DIMINISHED RESPONSE TO ANTILEUKOTRIENE TREATMENT IN;   adult onset asthma;   airway hyperresponsiveness
 related_synonym: ASRT1;   ASRT2;   ASRT3;   ASRT4;   ASRT5;   ASRT6;   ASRT7;   ASRT8;   Asthma-Related Traits, Susceptibility To, 1;   Asthma-Related Traits, Susceptibility To, 2;   Asthma-Related Traits, Susceptibility To, 3;   Asthma-Related Traits, Susceptibility To, 4;   Asthma-Related Traits, Susceptibility To, 5;   Asthma-Related Traits, Susceptibility To, 6;   Asthma-Related Traits, Susceptibility To, 7;   Asthma-Related Traits, Susceptibility To, 8;   allergic airway inflammation;   asthma and allergic rhinitis, susceptibility to;   asthma and atopy, susceptibility to;   asthma, protection against;   asthma, susceptibility to;   asthma-traits, susceptibility to asthma, protection against;   beta-2-adrenoreceptor agonist, reduced response to;   childhood athma, susceptibility to;   rhinoconjunctivitis, susceptibility to
 primary_id: MESH:D001249
 alt_id: MIM:600807;   MIM:601690;   MIM:607277;   MIM:608584;   MIM:609958;   MIM:610906;   MIM:611064;   MIM:611403;   MIM:611960;   MIM:613207
 xref: EFO:0000270;   EFO:0005414;   EFO:1002011;   GARD:10246;   ICD10CM:J45;   ICD9CM:493;   MONDO:0004979;   NCI:C28397
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 IEP protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:18931056 RGD:5128825 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association IAGP RGD PMID:19771478 PMID:16008680 RGD:5128835, RGD:5128831 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme susceptibility IAGP DNA:polymorphism (human) RGD PMID:19484664 PMID:19383228 RGD:4140913, RGD:4140919 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 IDA DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G ADA adenosine deaminase susceptibility IAGP DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 no_association
disease_progression
susceptibility		 ISO
IAGP
IEA
IEP		 mRNA:increased expression:lung
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :p.M764T (human)
DNA:SNPs: :multiple (human)
DNA:SNPs (human)		 RGD
GAD		 PMID:19635592 PMID:16893396 PMID:15118671 PMID:17339047 PMID:17961406 More... RGD:4145360, RGD:4145382, RGD:1331525, RGD:4145380, RGD:4145379, RGD:4145378, RGD:4145359 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 severity ISO
IEP		 mRNA:increased expression:respiratory tract
mRNA:increased expression:bronchus		 RGD PMID:19373511 PMID:17339047 PMID:20194813 RGD:5128878, RGD:4145380, RGD:5128872 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G ADCY2 adenylate cyclase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081 		JBrowse link
G ADCYAP1R1 ADCYAP receptor type I EXP CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,474 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO
IAGP
IEP		 DNA:SNPs: :rs1154404, rs28730619 (human)
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128892, RGD:5128882, RGD:5128891, RGD:5128890 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADORA1 adenosine A1 receptor IAGP
ISO
IEP		 DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus		 RGD PMID:19019667 PMID:20400685 PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA2A adenosine A2a receptor ISO
IAGP		 mRNA:decreased expression:aorta
DNA:SNP (human)		 RGD PMID:17293374 PMID:18310516 PMID:19019667 PMID:16339780 RGD:4890380, RGD:4890366, RGD:4890386, RGD:4890385 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility IAGP
IDA
ISO
IEA		 DNA:polymorphism: :p.R16G (human)
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :p.Q27E (human)
DNA:SNPs:promoter:multiple (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:SNP: :-1023A>G (human)		 ClinVar
RGD		 PMID:8383511 PMID:15284533 PMID:16596417 PMID:19800676 PMID:1655856 More... RGD:4145061, RGD:5129113, RGD:4145096, RGD:4145105, RGD:4145108, RGD:4145107, RGD:4145094, RGD:4145081, RGD:1331525, RGD:4145092 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
onset		 IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)		 CTD
RGD		 PMID:23304218 PMID:33075463 PMID:21920897 PMID:23304218 RGD:7244279, RGD:6767554, RGD:7244279 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:17877756 PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IEA
EXP		 CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 PMID:15118671 RGD:1331525 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:19628725 PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase no_association
treatment
severity		 IAGP
EXP
IEP
ISO
IMP		 DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)		 OMIM
CTD
RGD		 PMID:20128419 PMID:9642160 PMID:12911785 PMID:8879219 PMID:19033731 More... RGD:4890407, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890408, RGD:4890422, RGD:734557, RGD:4890413, RGD:4890415, RGD:4890410 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association
susceptibility		 IAGP
IEP
ISO		 DNA:polymorphism:promoter (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:SNPs (human)
DNA:SNP: :rs10507391 (human)		 RGD PMID:20128419 PMID:9642160 PMID:10527888 PMID:12911785 PMID:15784112 More... RGD:4890407, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890409, RGD:4890405 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426 		JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEP protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328 		JBrowse link
G ANG angiogenin severity IEP protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARG1 arginase 1 IAGP
EXP
ISO
IEP		 DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
mRNA, protein:increased expression:lung, mononuclear cell (human)		 CTD
RGD		 PMID:19281908 PMID:19800904 PMID:20124949 PMID:12813022 PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ARG2 arginase 2 severity
susceptibility		 IAGP
EXP
ISO		 DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)		 CTD
RGD		 PMID:19281908 PMID:20124949 PMID:12813022 PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDKRB2 bradykinin receptor B2 onset IAGP
IEP
IMP
ISO		 DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil		 RGD PMID:11517947 PMID:19038786 PMID:8856156 PMID:14727005 RGD:4890456, RGD:4891028, RGD:4891042, RGD:4890454 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BDNF brain derived neurotrophic factor susceptibility
severity		 IDA
IAGP
IEP		 DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
protein:increased expression:plasma
protein:decreased expression:blood, eosinophil		 RGD PMID:11737043 PMID:21723144 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891123, RGD:8655967, RGD:4891067, RGD:4891117, RGD:4891063, RGD:4891122 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IEP protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IEP protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G C3 complement C3 severity ISO
IEP
IAGP		 protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum
Interaction with IL4RA
DNA:SNP:intron:rs11569562 (human)
DNA:SNPs: :multiple (human)
DNA:SNP: :4896C>T (human)		 RGD PMID:20802484 PMID:20589464 PMID:20402389 PMID:20395963 PMID:18566738 More... RGD:5129681, RGD:5129519, RGD:5129537, RGD:5129538, RGD:5129501, RGD:5129505, RGD:5129512, RGD:5129517 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 severity ISO
IAGP
IEP		 mRNA:increased expression:lung
protein:increased expression:lung, leukocyte		 RGD PMID:20045013 PMID:15278436 PMID:20802484 PMID:17544263 PMID:17544263 More... RGD:5129686, RGD:5129512, RGD:5129681, RGD:5129560, RGD:5129560, RGD:5129561 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5 complement C5 severity IAGP
ISO
IEP		 mRNA:decreased expression:lung RGD PMID:15278436 PMID:20802484 PMID:20143644 PMID:11591795 PMID:10973279 RGD:5129512, RGD:5129681, RGD:5129706, RGD:1600651, RGD:5130158 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G C5AR1 complement C5a receptor 1 severity ISO
IEP		 protein:increased expression:respiratory tract
protein:increased expression:lung, leukocyte		 RGD PMID:20802484 PMID:15940127 PMID:16511606 PMID:17544263 RGD:5129681, RGD:5129561, RGD:5130166, RGD:5129560 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CARD11 caspase recruitment domain family member 11 susceptibility ISO
IAGP		 ClinVar Annotator: match by term: Asthma ClinVar
RGD		 PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 PMID:25741868 More... RGD:11100037 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CARD11-AS1 CARD11 antisense RNA 1 IAGP ClinVar Annotator: match by term: Asthma ClinVar PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 PMID:25741868 More... NCBI chr 7:2,944,035...2,947,087
Ensembl chr 7:2,944,027...2,947,091 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:10,871,553...10,923,075
Ensembl chr19:10,871,553...10,923,075 		JBrowse link
G CASP1 caspase 1 IEP protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CAT catalase severity IEP
EXP
IDA
IAGP		 protein:increased expression:erythrocyte
CTD Direct Evidence: marker/mechanism
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
DNA:polymorphism:promoter:-21A>T (human)		 CTD
RGD		 PMID:18048809 PMID:19475625 PMID:16622028 PMID:18048809 PMID:19373626 RGD:5130751, RGD:5130867, RGD:5130856, RGD:5130753 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 treatment
susceptibility
severity		 ISO
IAGP
EXP
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung		 OMIM
CTD
RGD		 PMID:17060636 PMID:22932891 PMID:16304252 PMID:17074272 PMID:9034156 More... RGD:4891485, RGD:7248416, RGD:5130930, RGD:4145461, RGD:4145451, RGD:4145457, RGD:4145392, RGD:4145387 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO
IEP		 mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:15993846 PMID:20074456 PMID:15947487 PMID:20237293 PMID:11160256 RGD:2306304, RGD:4145487, RGD:4145513, RGD:4145486, RGD:4145603 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 IEP protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment
severity		 IEP
EXP
ISO
IAGP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
protein:increased expression:serum		 CTD
RGD		 PMID:19373627 PMID:20205697 PMID:12055264 PMID:25441643 PMID:23454776 More... RGD:4145509, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4891466 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 IEP protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum		 RGD PMID:18422729 PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO
IEP		 protein:increased expression:respiratory system fluid/secretion
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung		 RGD PMID:18316417 PMID:10384142 PMID:18684970 PMID:15993846 RGD:4891474, RGD:4891475, RGD:4145489, RGD:2306304 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 susceptibility IAGP
IEP
ISO
IMP		 DNA:SNP: :1265A>G (human)
protein:increased expression:plasma
DNA:SNPs: :179T>C, 275C>T (human)
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:12761043 PMID:16304252 PMID:15207712 PMID:18712274 PMID:17060636 More... RGD:5130932, RGD:5130930, RGD:4891495, RGD:4891483, RGD:4891485, RGD:4891484, RGD:4891496 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment IAGP
ISO
IEP		 DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)		 RGD PMID:18712274 PMID:25399816 PMID:25530546 PMID:16304252 PMID:15207712 RGD:4891483, RGD:11087575, RGD:11081163, RGD:5130930, RGD:4891495 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CCL27 C-C motif chemokine ligand 27 IEP RGD PMID:19541356 RGD:5130899 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048 		JBrowse link
G CCL28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP RGD PMID:18774390 RGD:5130915 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO
EXP
IAGP		 protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)		 CTD
RGD		 PMID:8534483 PMID:20092989 PMID:18208670 PMID:20430255 RGD:4891430, RGD:2307112, RGD:4891381 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO
IEP		 Promoter polymorphism RGD PMID:19965981 PMID:21388664 RGD:5130979, RGD:5130983 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections		 RGD PMID:15654816 PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility IAGP
ISO		 DNA:SNP:cds:p.V64I (human)
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)		 RGD PMID:17298432 PMID:23454776 PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO
IEP
IAGP		 protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)		 RGD PMID:16978084 PMID:19017998 PMID:20220260 PMID:19657453 PMID:20134116 More... RGD:4145646, RGD:4145632, RGD:4145638, RGD:4145623, RGD:4145618, RGD:4145633, RGD:1601020 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association IEP
IAGP
ISO		 protein:decreased expression:blood, lymphocyte (human)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
mRNA:increased expression:lung (mouse)		 RGD PMID:15256090 PMID:23454776 PMID:16474097 PMID:20220260 PMID:18094012 RGD:4892108, RGD:8551842, RGD:4892093, RGD:4145638, RGD:4892088 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,551,081...40,565,472 		JBrowse link
G CCR8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680 		JBrowse link
G CCR9 C-C motif chemokine receptor 9 IEP mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174 		JBrowse link
G CD14 CD14 molecule no_association
severity
susceptibility		 IAGP
EXP
IEP		 DNA:polymorphism:promoter:c. -159C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :
protein:increased expression:serum
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)		 CTD
RGD		 PMID:17607003 PMID:15741437 PMID:19096003 PMID:16387800 PMID:16387800 More... RGD:4144815, RGD:4144228, RGD:4144813, RGD:4144813, RGD:4144208, RGD:4144814 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD1D CD1d molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD209 CD209 molecule IEP RGD PMID:21471959 RGD:5131188 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G CD274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD28 CD28 molecule IEP RGD PMID:21356099 RGD:5131612 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CD40 CD40 molecule treatment IEP
ISO
IAGP		 RGD PMID:19220210 PMID:20205594 PMID:20941750 PMID:19159017 RGD:5132272, RGD:8547792, RGD:4892277, RGD:4144188 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21352203 PMID:21051864 PMID:21440530 RGD:5132620, RGD:5132621, RGD:5132619 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD86 CD86 molecule treatment ISO
IEP
IAGP		 protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)		 RGD PMID:20941750 PMID:25344652 PMID:9449507 PMID:20668438 PMID:9551945 More... RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CDH1 cadherin 1 IAGP RGD PMID:21540309 RGD:5132878 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDHR3 cadherin related family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 7:105,963,264...106,036,432
Ensembl chr 7:105,876,796...106,036,432 		JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility IAGP DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHAT choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CHI3L1 chitinase 3 like 1 susceptibility IMP
IAGP
IEP		 human gene in mouse model
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)		 OMIM
ClinVar
RGD		 PMID:18403759 PMID:19414556 PMID:19568425 PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHIA chitinase acidic no_association IAGP
ISO
IEP		 DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)		 RGD PMID:16179638 PMID:20226308 PMID:19548841 PMID:15192232 PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 1:111,290,851...111,320,563
Ensembl chr 1:111,290,851...111,320,566 		JBrowse link
G CHML CHM like Rab escort protein IAGP RGD PMID:18343558 RGD:5133238 NCBI chr 1:241,628,851...241,640,369
Ensembl chr 1:241,628,851...241,640,369 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 IAGP RGD PMID:16931638 RGD:5133416 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 IAGP DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 severity IEP
ISO		 RGD PMID:20394512 PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CLCA1 chloride channel accessory 1 susceptibility IDA
ISO
IAGP		 DNA:SNPs (human) RGD PMID:17898169 PMID:11296262 PMID:15318163 RGD:4145653, RGD:4145661, RGD:4145656 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259 		JBrowse link
G CLDN18 claudin 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655 		JBrowse link
G CMA1 chymase 1 severity
no_association
susceptibility		 IEP
IAGP		 protein:increased expression:lung epithelium, mast cell (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)		 RGD PMID:20813890 PMID:15248847 PMID:15924217 RGD:5128804, RGD:1625397, RGD:1625396 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 IAGP DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)		 RGD PMID:19663668 PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 IAGP DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 severity ISO
IEP		 protein:increased expression:lung
protein:increased expression:sputum		 RGD PMID:20405019 PMID:9717963 PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439 		JBrowse link
G CSF3 colony stimulating factor 3 IDA
ISO		 protein:increased expression:lung RGD PMID:21396376 PMID:20405019 RGD:5133731, RGD:5131473 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 severity
treatment
no_association		 IEP
EXP
ISO
IDA
IAGP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:SNPs: :multiple (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)		 CTD
RGD		 PMID:28807506 PMID:15871446 PMID:11726402 PMID:17237396 PMID:16677453 More... RGD:4891529, RGD:11344922, RGD:4891514, RGD:4891517, RGD:4891510, RGD:4891526, RGD:4891522, RGD:4891521, RGD:4891528, RGD:4891516, RGD:4891519, RGD:4891527 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTNNA3 catenin alpha 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 no_association ISO
IAGP		 DNA:polymorphisms: :p.V249I, p.T280M (human)
DNA:SNPs: :p.V249I, rs2669849 (human)		 RGD PMID:21037587 PMID:17505143 PMID:17082760 RGD:4891882, RGD:4891904, RGD:4891895 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 severity IEP RGD PMID:20371397 RGD:5134983 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEP
ISO		 protein:decreased expression:plasma RGD PMID:17302903 PMID:16602032 PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP
ISO		 mRNA:increased expression:bronchus epithelium RGD PMID:17234659 PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO RGD PMID:9620668 RGD:5135265 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 susceptibility
severity		 ISO
IAGP
IEP		 DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell		 RGD PMID:18094012 PMID:16043121 PMID:16548899 PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CYBA cytochrome b-245 alpha chain susceptibility IAGP DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
DNA:polymorphism: :-930A>G (human)		 RGD PMID:18716406 PMID:19459419 RGD:4772770, RGD:4311041 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) IAGP DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IEP
EXP
ISO		 mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28807506 PMID:20514434 PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 no_association
severity		 IAGP
IMP
ISO
IEP		 DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa 		RGD PMID:16771777 PMID:16630147 PMID:17153879 PMID:16776674 PMID:11591188 More... RGD:4889116, RGD:4784257, RGD:4781742, RGD:4782072, RGD:4848936, RGD:4888514, RGD:4843543, RGD:4781449, RGD:4847129 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 IAGP DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)		 RGD PMID:15475736 PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226 		JBrowse link
G DCN decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DEFB1 defensin beta 1 susceptibility IAGP DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)		 RGD PMID:15696078 PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936 		JBrowse link
G DNAH5 dynein axonemal heavy chain 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:13,690,328...14,011,818
Ensembl chr 5:13,690,328...14,011,818 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO
EXP		 DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23423710 PMID:23196709 RGD:9588646 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DPP10 dipeptidyl peptidase like 10 IAGP
IEA
ISO		 DNA:SNPs (human)
DNA:SNP: :rs10208402 (human)
protein:increased expression:bronchus
DNA:SNP:exon (human)		 RGD
GAD		 PMID:21103062 PMID:19672052 PMID:15118671 PMID:17967935 PMID:14566338 RGD:4889866, RGD:4892275, RGD:1331525, RGD:4892278, RGD:4892276 NCBI chr 2:114,442,641...115,845,780
Ensembl chr 2:114,442,299...115,845,780 		JBrowse link
G EBI3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr19:4,229,523...4,237,528
Ensembl chr19:4,229,523...4,237,528 		JBrowse link
G EDN1 endothelin 1 IEP
EXP
IAGP		 Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)		 CTD
RGD		 PMID:16981460 PMID:20588001 PMID:11668616 RGD:4144895, RGD:4144869 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892322, RGD:4892288 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B IAGP
ISO		 DNA:polymorphism (human)
mRNA:increased expression:bronchus, smooth muscle cell		 RGD PMID:17470272 PMID:15245576 PMID:18632188 RGD:4892321, RGD:4892324, RGD:4892288 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EGFR epidermal growth factor receptor severity IEP
ISO		 protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (rat)
protein:increased expression:lung epithelium (mouse)		 RGD PMID:12580917 PMID:21224214 PMID:19954006 PMID:21072743 RGD:5131468, RGD:5131633, RGD:5131870, RGD:5131642 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 IEP
IAGP
ISO		 mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)		 RGD PMID:18774390 PMID:18507785 PMID:11254538 RGD:5130915, RGD:5131993, RGD:5131985 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 no_association IAGP RGD PMID:12774215 PMID:11281413 RGD:5129158, RGD:5129157 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328 		JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility IAGP DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPX eosinophil peroxidase severity
disease_progression		 IEP protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423 PMID:12199967 PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174 		JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus		 RGD PMID:21658190 PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 IDA RGD PMID:19864598 RGD:4892589 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCER1A Fc epsilon receptor Ia severity IEP Fatal asthma subjects
Asthma symptoms persistent despite steroids		 RGD PMID:20937062 PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224 		JBrowse link
G FCGR2A Fc gamma receptor IIa IEP protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR2B Fc gamma receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 IAGP ClinVar Annotator: match by term: Asthma ClinVar NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FOXP3 forkhead box P3 treatment EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27965764 PMID:29317916 PMID:28944907 PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GATA3 GATA binding protein 3 ISO
IEP		 RGD PMID:18186587 PMID:9949310 RGD:5128803, RGD:5128802 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GC GC vitamin D binding protein ISO
IEP		 protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GSDMB gasdermin B EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr17:39,904,595...39,918,635
Ensembl chr17:39,904,595...39,919,854 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 susceptibility IAGP DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 resistance
susceptibility		 IAGP
EXP		 DNA:deletion: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16870661 PMID:18988661 PMID:17651144 PMID:21051083 PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTM3 glutathione S-transferase mu 3 IAGP
IEP		 DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135039, RGD:5135038 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038 		JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility IAGP DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 no_association
susceptibility
disease_progression
severity		 IAGP
EXP
ISO		 DNA:SNPs: :p.I105V, p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
DNA:polymorphism:exon:p.I105V (rs1695) (human)		 CTD
RGD		 PMID:11994713 PMID:16870661 PMID:18988661 PMID:24117884 PMID:29411558 More... RGD:4142519, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4140947, RGD:4140946, RGD:4142526 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:15300848 PMID:21051083 PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921
G HAVCR1 hepatitis A virus cellular receptor 1 IEP RGD PMID:20628202 RGD:5128851 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HDAC2 histone deacetylase 2 IEP mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDC histidine decarboxylase IAGP associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility IAGP DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP
EXP		 DNA:haplotype
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:5143938, RGD:13506911 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP
EXP		 DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human) 		CTD
RGD		 PMID:10792356 PMID:12890388 PMID:10051703 PMID:11802952 PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 susceptibility IAGP DNA:polymorphism: :rs3916765(human) RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,741,391...32,747,198
Ensembl chr 6:32,741,391...32,747,198 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility
disease_progression
no_association		 IAGP
EXP		 Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)		 CTD
RGD		 PMID:10792356 PMID:20298583 PMID:20159242 PMID:20214848 PMID:23331206 More... RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha susceptibility IAGP DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility
no_association
severity		 IAGP
EXP		 DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human) 		CTD
RGD		 PMID:16792590 PMID:20214848 PMID:20159242 PMID:23331206 PMID:10051703 More... RGD:4144181, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144196 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 susceptibility IAGP RGD PMID:22397267 RGD:13506905
G HLA-G major histocompatibility complex, class I, G susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD		 PMID:15611928 RGD:5144118 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:20084838 RGD:5508450 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 severity IEP
EXP
ISO		 mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18048809 PMID:16196283 PMID:20596599 RGD:4145408, RGD:4145403 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNMT histamine N-methyltransferase no_association
susceptibility		 IAGP
EXP		 ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:10752634 PMID:10803682 PMID:16205835 PMID:17651147 PMID:25741868 More... RGD:5128885, RGD:5128881, RGD:5128883, RGD:5128888, RGD:5128887 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364 		JBrowse link
G HP haptoglobin IEP RGD PMID:21471098 PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO
EXP
IEP		 mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung, serum (rat)
protein:increased secretion:lung (human)		 CTD
RGD		 PMID:17014439 PMID:25003170 PMID:20400685 PMID:20953388 PMID:20205697 RGD:4145444, RGD:4145331, RGD:4145509 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma treatment
resistance		 IEP
ISO
IEA		 protein:increased expression:sputum RGD
GAD		 PMID:20817868 PMID:12396623 PMID:15118671 PMID:20953328 PMID:19542437 RGD:4145651, RGD:10755706, RGD:1331525, RGD:4145525, RGD:5128479 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO
IAGP		 DNA: SNP: Leu467Pro RGD PMID:21737883 PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449 		JBrowse link
G IFNL1 interferon lambda 1 exacerbates IEP associated with common cold;mRNA:decreased expression:sputum (human)
associated with common cold;protein:increased expression: nasal cavity (human)		 RGD PMID:25784275 PMID:22135341 RGD:126848770, RGD:126848775 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,715...39,864,312 		JBrowse link
G IL10 interleukin 10 treatment
susceptibility		 ISO
EXP
IAGP
IEP		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma		 CTD
RGD		 PMID:29317916 PMID:20560982 PMID:21998459 PMID:12938145 PMID:20237464 More... RGD:5131623, RGD:11046261, RGD:4143221, RGD:4140471, RGD:4140421, RGD:4140459, RGD:4140451 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B severity
susceptibility		 IAGP DNA:polymorphisms:introns:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter
DNA:polymorphisms:promoter, 3'utr:		 ClinVar
RGD		 PMID:15322986 PMID:15322986 PMID:12241719 PMID:16210052 RGD:1600043, RGD:4145428, RGD:4145438 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13 interleukin 13 susceptibility
severity
no_association		 IAGP
EXP
IEP
ISO		 DNA:polymorphism:promoter:c. -1055C>T (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
protein:increased expression:serum
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c. 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:polymorphism: :c. 1923C>T (human)
DNA:SNP: :c. -646A>G (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism:cds:p.R130Q (human)
protein:increased expression:sputum		 ClinVar
OMIM
CTD
RGD		 PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 More... RGD:4220633, RGD:8549509, RGD:4892639, RGD:4763153, RGD:2301686, RGD:4765128, RGD:4145776, RGD:4145453, RGD:4145508, RGD:2307110, RGD:4145639, RGD:4145601, RGD:4145664, RGD:4321828, RGD:4145775, RGD:4146241, RGD:4145534, RGD:4145593, RGD:4763761, RGD:4145777, RGD:4206706 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 no_association ISO
IAGP		 DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :1398A>G (human)
DNA:polymorphism: :1050C>T (human)		 RGD PMID:11714828 PMID:18480254 PMID:17392323 PMID:20383033 PMID:17006604 More... RGD:4892654, RGD:4892647, RGD:4892650, RGD:4892646, RGD:4892639, RGD:4892655 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO
IEP		 mRNA:increased expression:bronchus
protein:increased expression:serum		 RGD PMID:20383033 PMID:21462799 PMID:17885690 RGD:4892646, RGD:8549521, RGD:4892649 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL15 interleukin 15 no_association IAGP
ISO		 DNA:SNPs: :multiple (human) RGD PMID:19133918 PMID:16629787 PMID:11160248 PMID:15843549 PMID:15131572 RGD:5000760, RGD:4984421, RGD:4990462, RGD:5000757, RGD:5000758 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL16 interleukin 16 no_association
severity		 IAGP
IEP
ISO		 DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum		 RGD PMID:15784111 PMID:16734115 PMID:12872394 PMID:10585533 PMID:16387589 RGD:5024935, RGD:5024928, RGD:5024930, RGD:5024937, RGD:5024934 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058 		JBrowse link
G IL17A interleukin 17A susceptibility IEP
ISO
IAGP		 protein:increased expression:sputum
DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:alveolar macrophage
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum		 RGD PMID:15730730 PMID:20351038 PMID:20437253 PMID:18941201 PMID:18060619 RGD:4889114, RGD:4888527, RGD:4889139, RGD:4889152, RGD:4839043 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL17RB interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794 		JBrowse link
G IL18 interleukin 18 severity
susceptibility
disease_progression		 IAGP
ISO
IMP
IEP		 DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
DNA:polymorphism: :c. -105A>C (human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
protein:increased expression:serum		 RGD PMID:17767553 PMID:18826499 PMID:20497957 PMID:20497957 PMID:16433859 More... RGD:4889585, RGD:4889908, RGD:4889898, RGD:4889898, RGD:4889923, RGD:4889910, RGD:4889900, RGD:4889863 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL18R1 interleukin 18 receptor 1 IAGP
ISO		 DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)		 RGD PMID:18774397 PMID:19910030 PMID:20860503 PMID:11972614 PMID:18382474 RGD:5024946, RGD:5024945, RGD:5024942, RGD:5024948, RGD:5024947 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL19 interleukin 19 IEP protein:increased expression:serum RGD PMID:15557163 RGD:5037236 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981 		JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta susceptibility IAGP
EXP
ISO
IEP		 DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil		 CTD
RGD		 PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142864, RGD:4142836, RGD:4142830 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 susceptibility
severity		 ISO
EXP
IAGP
IEP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)		 CTD
RGD		 PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835 More... RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist severity
susceptibility		 IEP
EXP
IAGP
IMP		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:intron (human)
DNA:SNP: :rs2234678 (human)
DNA:SNPs: :rs447713, rs3087271 (human)
DNA:SNPs: :multiple (human)
DNA, protein:repeat, decreased expression (human)		 CTD
RGD		 PMID:9176529 PMID:10843772 PMID:18926055 PMID:17107994 PMID:16409203 More... RGD:4143225, RGD:4142864, RGD:4143208, RGD:4143163, RGD:4143209, RGD:4143216, RGD:4142802, RGD:4143224 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 susceptibility IEP
IAGP		 DNA:SNP:promoter:rs2069762(human) RGD PMID:20926789 PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL21 interleukin 21 IAGP DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL22 interleukin 22 treatment
severity		 ISO
IEP		 mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum		 RGD PMID:21789181 PMID:21998459 PMID:21535180 PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL23R interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr14:23,372,809...23,376,403
Ensembl chr14:23,372,809...23,376,403 		JBrowse link
G IL27 interleukin 27 susceptibility
treatment		 IAGP
ISO
IEP		 DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum		 RGD PMID:17318299 PMID:26595888 PMID:17878337 PMID:20817868 PMID:19542437 RGD:5128485, RGD:11076728, RGD:5128491, RGD:4145651, RGD:5128479 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:21377197 PMID:20525707 RGD:5147437, RGD:5147445 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta IAGP
ISO		 DNA:SNP: :rs2284033 (human) RGD PMID:20860503 PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
G IL3 interleukin 3 susceptibility IAGP DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)		 RGD PMID:24684517 PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL32 interleukin 32 IEP protein:increased expression:blood serum (human) RGD PMID:22336080 RGD:150340749 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL33 interleukin 33 treatment
severity		 EXP
ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease		 CTD
RGD		 PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999 More... RGD:39939002, RGD:39938968 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 treatment
no_association		 IAGP
EXP
ISO
IEP		 DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
mRNA:increased expression:lung, spleen
protein:increased expression:respiratory system fluid/secretion		 CTD
RGD		 PMID:18357729 PMID:21103062 PMID:24946644 PMID:24450480 PMID:18211752 More... RGD:4889866, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:5128500, RGD:5128502, RGD:5128557 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor susceptibility
severity
disease_progression		 ISO
ISS
IAGP
IDA
IEP		 DNA:mutation:cds:p.Q576R (mouse)
OMIM:600807
DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
protein:increased secretion:plasma
DNA:polymorphism:cds:p.Q576R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:SNPs:cds:p.E375A, Q551R (human)		 MouseDO
RGD		 PMID:19770271 PMID:15479272 PMID:12133990 PMID:18425216 PMID:17586032 More... RGD:4890003, RGD:4890351, RGD:4890404, RGD:4890346, RGD:4890348, RGD:4890406, RGD:4890387, RGD:4890347, RGD:4890351, RGD:4890402, RGD:5128514, RGD:4890024, RGD:5128553, RGD:4890352, RGD:4890349 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL5 interleukin 5 treatment
disease_progression		 ISO
EXP
IEP
IAGP
IDA		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism:promoter:-703C>T (human)		 CTD
RGD		 PMID:7540862 PMID:23266719 PMID:19947994 PMID:25008888 PMID:11159041 More... RGD:4890938, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890962, RGD:4890947, RGD:4890963, RGD:4145461, RGD:4890940, RGD:4890948 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL5RA interleukin 5 receptor subunit alpha IAGP
ISO
IEP
IMP		 DNA:SNPs (human)
DNA:SNP: :c.25091G>A (human)		 RGD PMID:16217591 PMID:17276963 PMID:20592918 PMID:10224351 PMID:20513521 More... RGD:5128626, RGD:5128617, RGD:5128614, RGD:5128623, RGD:5128625, RGD:5128627 NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613 		JBrowse link
G IL6 interleukin 6 IEP
EXP
ISO		 associated with Hypersensitivity;protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:29902480 PMID:20816188 PMID:20840469 PMID:20658762 PMID:21115736 RGD:4143266, RGD:4143265, RGD:4143271, RGD:5128630 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:29902480 PMID:17496315 PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IL9 interleukin 9 ISO
IMP
IEP		 protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm		 RGD PMID:12153980 PMID:21356110 PMID:15531759 PMID:17446528 PMID:15303135 RGD:5128700, RGD:5128707, RGD:5128690, RGD:5128686, RGD:5128691 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841 		JBrowse link
G IL9R interleukin 9 receptor IEP RGD PMID:10629460 RGD:5128704 NCBI chr  X:155,997,696...156,013,020
NCBI chr  Y:57,184,072...57,197,869
Ensembl chr  X:155,997,696...156,013,017
Ensembl chr  Y:155,997,696...156,013,017 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 susceptibility IAGP ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar		 PMID:17503328 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRF1 interferon regulatory factor 1 no_association
susceptibility		 IAGP
IEP		 DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)		 RGD PMID:11069564 PMID:10225979 PMID:16961714 RGD:5128726, RGD:5128723, RGD:5128724 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G ITGB3 integrin subunit beta 3 IAGP DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G ITGB6 integrin subunit beta 6 ISS OMIM:600807 MouseDO NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,271,888 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G KDR kinase insert domain receptor ISO
IEP		 associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519 PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIF3A kinesin family member 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:132,688,812...132,737,546
Ensembl chr 5:132,692,628...132,737,638 		JBrowse link
G KRT19 keratin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G LEP leptin IEP protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LGALS3 galectin 3 treatment IMP RGD PMID:16424226 RGD:9685213 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LOC129994952 ATAC-STARR-seq lymphoblastoid silent region 16492 IAGP ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to ClinVar PMID:16596417 NCBI chr 5:148,826,740...148,826,879 JBrowse link
G LTA lymphotoxin alpha susceptibility
no_association		 IAGP DNA:polymorphisms:promoter
DNA:polymorphism:intron		 RGD PMID:15969671 PMID:18947013 PMID:12530118 PMID:17536219 RGD:4143373, RGD:4143370, RGD:4143254, RGD:4143371 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)		 RGD PMID:22512728 PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin susceptibility IAGP DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G MIF macrophage migration inhibitory factor severity IAGP
ISO
IEP		 DNA:SNP:promoter:rs755622(human)
protein:increased expression:bronchoalveolar lavage fluid
DNA:repeats:promoter		 RGD PMID:19317738 PMID:17373669 PMID:9637721 PMID:16455830 PMID:16186482 RGD:4891059, RGD:4891035, RGD:4891043, RGD:1641985, RGD:4891052 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MMP1 matrix metallopeptidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
EXP
IMP
IAGP
ISO		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung		 CTD
RGD		 PMID:11742282 PMID:15131573 PMID:21439806 PMID:19940022 PMID:20181264 More... RGD:5129204, RGD:5129522, RGD:5130859, RGD:2325953, RGD:5129687 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase susceptibility IEP
IAGP		 protein:increased expression:serum
DNA:polymorphism: :−463G > A (human)		 RGD PMID:10731862 PMID:19544176 RGD:5130994, RGD:5130989 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility IAGP DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNP: : -109C>T (human)		 RGD PMID:19218813 PMID:21320344 PMID:8817330 PMID:19862939 RGD:5131151, RGD:5131149, RGD:1599903, RGD:5131092 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming IAGP
ISO		 associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment IEP
ISO		 protein:increased expression:lung
mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:17698377 PMID:21549818 PMID:21780541 PMID:14594655 PMID:17590487 RGD:5131204, RGD:7364729, RGD:7349407, RGD:7349354, RGD:2324962 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IEP
ISO		 protein:altered expression:sputum RGD PMID:11802783 PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MUC7 mucin 7, secreted IAGP
EXP		 ClinVar Annotator: match by term: Asthma, protection against
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:11378823 PMID:16759176 PMID:28492532 NCBI chr 4:70,430,492...70,482,997
Ensembl chr 4:70,430,492...70,482,997 		JBrowse link
G MYB MYB proto-oncogene, transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYLK myosin light chain kinase IAGP RGD PMID:17472811 RGD:4891492 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP Asthma, Aspirin-Induced; DNA:polymorphism: :
DNA:polymorphisms: :		 RGD PMID:20602614 PMID:16924569 RGD:5131600, RGD:5131606 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 severity IEP mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NGF nerve growth factor severity IDA
IEP
ISO		 protein:increased expression:lung, serum
protein:increased expression:blood, eosinophil		 RGD PMID:11737043 PMID:17164945 PMID:17497413 PMID:12752594 RGD:4891123, RGD:4891108, RGD:4891068, RGD:4891122 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:16603479 PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility IAGP DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:		 RGD PMID:16918516 PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP
ISO		 DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS1 nitric oxide synthase 1 susceptibility IAGP DNA:repeats: :
DNA:repeats:intron
DNA:repeats:exon		 RGD PMID:10673365 PMID:20609134 PMID:14767694 PMID:10833424 RGD:5132869, RGD:5132863, RGD:5132615, RGD:5132860 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 disease_progression
no_association
severity		 ISO
EXP
IEP
IAGP		 protein:increased expression:lung, bronchoalveolar lavage fluid
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeat:promoter
DNA:repeats:promoter
mRNA:increased expression:monocyte
DNA:repeats:promoter, introns (human)
DNA:SNP:exon:p.S608L (human)		 CTD
RGD		 PMID:19800904 PMID:17161822 PMID:21847581 PMID:18254476 PMID:16703578 More... RGD:4891927, RGD:5509073, RGD:4891910, RGD:4891953, RGD:4891508, RGD:4891419, RGD:4891957, RGD:4891924, RGD:4891925, RGD:4891480 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility IAGP DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)		 RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892062, RGD:4892058, RGD:4892053 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPSR1 neuropeptide S receptor 1 susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2		 OMIM
CTD
ClinVar
RGD		 PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187 PMID:17702965 More... RGD:4891923, RGD:4891921, RGD:4891922 NCBI chr 7:34,658,218...34,878,332
Ensembl chr 7:34,658,218...34,878,332 		JBrowse link
G NPSR1-AS1 NPSR1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 ClinVar PMID:15073379 NCBI chr 7:34,346,512...34,834,331
Ensembl chr 7:34,287,269...34,871,582 		JBrowse link
G NPY neuropeptide Y EXP CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility IDA
EXP
IAGP		 DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)		 CTD
RGD		 PMID:20049212 PMID:19027876 PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment
severity
susceptibility		 IEP
ISO
IDA
IAGP		 protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron		 RGD PMID:18396779 PMID:28297812 PMID:20727335 PMID:18799869 PMID:15295049 More... RGD:4892328, RGD:408364991, RGD:7174728, RGD:4892594, RGD:4892609, RGD:4892568 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NTF3 neurotrophin 3 IDA
ISO		 protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891123, RGD:4891068 NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536 		JBrowse link
G NTF4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr19:49,058,284...49,065,035
Ensembl chr19:49,061,066...49,065,076 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:20934630 PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr17:39,921,041...39,927,601
Ensembl chr17:39,921,041...39,927,601 		JBrowse link
G P2RY12 purinergic receptor P2Y12 IAGP
ISO		 RGD PMID:22010907 PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO
EXP
IDA		 CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell		 CTD
RGD		 PMID:18261157 PMID:12594058 PMID:26205779 PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDE4B phosphodiesterase 4B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PDE4D phosphodiesterase 4D EXP CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PGF placental growth factor IDA RGD PMID:22268141 RGD:6483605 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLA2G7 phospholipase A2 group VII IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10733466 PMID:10733466 RGD:1581025 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
G PLAU plasminogen activator, urokinase IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21912604 PMID:18519237 RGD:4892037 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,193,978...134,226,073 		JBrowse link
G PRF1 perforin 1 ISO RGD PMID:22250087 PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein severity
disease_progression
no_association		 IEP
ISO		 mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:		 RGD PMID:16982448 PMID:22022864 PMID:24450586 PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029 		JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr21:46,635,674...46,665,124
Ensembl chr21:46,635,595...46,665,685 		JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr11:20,387,716...20,509,338
Ensembl chr11:20,387,558...20,509,338 		JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr14:22,920,529...22,929,376
Ensembl chr14:22,920,525...22,929,408 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA RGD PMID:26381519 RGD:11099992 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGDR prostaglandin D2 receptor susceptibility IAGP OMIM NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 IAGP
EXP
ISO		 CTD Direct Evidence: therapeutic
Aspirin exacerbated asthma		 CTD
RGD		 PMID:27103662 PMID:19392992 PMID:19796209 PMID:18757520 RGD:5135019, RGD:5135020, RGD:5135018 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G PTGER3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility
severity		 ISO
IAGP
IMP		 mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)		 RGD PMID:19878559 PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 More... RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522, RGD:5135515 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059 		JBrowse link
G RAD50 RAD50 double strand break repair protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RNASE3 ribonuclease A family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr14:20,891,385...20,892,348
Ensembl chr14:20,891,385...20,892,348 		JBrowse link
G RUNX1 RUNX family transcription factor 1 IAGP DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX3 RUNX family transcription factor 3 ISS OMIM:600807 MouseDO NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 susceptibility ISO
IAGP
IEP		 mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum		 ClinVar
RGD		 PMID:9550363 PMID:9643286 PMID:12100044 PMID:12921604 PMID:21255142 More... RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility
severity
no_association		 IAGP
EXP
ISO
IEP		 DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, susceptibility to
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum		 CTD
OMIM
ClinVar
RGD		 PMID:11813133 PMID:11813133 PMID:15531759 PMID:16456148 PMID:17218572 More... RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191 		JBrowse link
G SELL selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SERPINA1 serpin family A member 1 ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINE1 serpin family E member 1 severity
no_association
susceptibility		 IEP
ISO
IAGP		 protein:increased expression:plasma
protein:increased activity, increased expression:plasma, lung
DNA:polymorphism:promoter:rs1799768 (human)		 RGD PMID:19703828 PMID:18594148 PMID:19604112 PMID:19063817 RGD:4144831, RGD:4144836, RGD:4144833, RGD:4144832 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFTPA1 surfactant protein A1 ISO
IEP		 protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung		 RGD PMID:15816355 PMID:16629790 PMID:18926058 PMID:18802356 RGD:4143398, RGD:4143462, RGD:4143289, RGD:4143516 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPB surfactant protein B IEP
ISO		 protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell		 RGD PMID:16629790 PMID:11472974 PMID:15816355 PMID:18926058 RGD:4143462, RGD:4143465, RGD:4143398, RGD:4143289 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C susceptibility IAGP
IEP
ISO		 DNA:polymorphism: :p.A53T (human)
protein:increased expression:lung
mRNA, protein:decreased expression:lung		 RGD PMID:19910179 PMID:16629790 PMID:11472974 RGD:4144063, RGD:4143462, RGD:4143465 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SFTPD surfactant protein D IEP
ISO
IDA		 associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung		 RGD PMID:18266831 PMID:11472974 PMID:16839409 PMID:16629790 PMID:18802356 RGD:4143517, RGD:4143465, RGD:4143508, RGD:4143462, RGD:4143516 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility IAGP DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 IDA RGD PMID:15743779 RGD:1581231 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPRR2B small proline rich protein 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:153,070,226...153,087,799
Ensembl chr 1:153,070,226...153,071,611 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28807506 PMID:18211752 RGD:2317290 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:19087723 PMID:16083555 RGD:7244151, RGD:7244153 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TAC1 tachykinin precursor 1 IEP protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TACR1 tachykinin receptor 1 ISO
IEP		 protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:17392578 PMID:8240667 PMID:16409782 RGD:2304339, RGD:5147645, RGD:5147475 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
G TACR2 tachykinin receptor 2 IAGP
IMP		 DNA:SNP:cds:p.G231E (human) RGD PMID:20175803 PMID:19880429 RGD:5147640, RGD:5147641 NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility IAGP DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TBX21 T-box transcription factor 21 EXP
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:600807		 CTD
MouseDO		 PMID:15806396 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility
severity		 IEA
IAGP		 ClinVar Annotator: match by term: Asthma
DNA:polymorphism:cds:924T>C(human)		 ClinVar
RGD		 PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:15118671 More... RGD:1331525, RGD:11059535, RGD:11059534 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
G TGFB1 transforming growth factor beta 1 onset
no_association		 IAGP
EXP
ISO
IEP		 DNA:SNP: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:915G>C (human)
protein:increased expression:serum
mRNA:increased expression:lung
DNA:SNPs:promoter, exon:multiple (human)
DNA:polymorphism: :-509C>T (human)
DNA:polymorphisms: :multiple (human)		 CTD
RGD		 PMID:16365456 PMID:19138248 PMID:17673695 PMID:18366906 PMID:19620629 More... RGD:4145295, RGD:4145280, RGD:4145132, RGD:4145142, RGD:4145139, RGD:4145113, RGD:4145143, RGD:4143443, RGD:4145144, RGD:4145299, RGD:4145297 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THBD thrombomodulin IDA RGD PMID:20709825 RGD:5684984 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TLR1 toll like receptor 1 susceptibility IAGP DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
G TLR10 toll like receptor 10 susceptibility IAGP DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:38,772,238...38,782,990
Ensembl chr 4:38,772,238...38,782,990 		JBrowse link
G TLR2 toll like receptor 2 severity
susceptibility		 IAGP
ISO		 DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs4696480 (human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)		 RGD PMID:19148143 PMID:22402138 PMID:18202345 PMID:20685742 PMID:20815312 More... RGD:2312679, RGD:7800732, RGD:4145343, RGD:4144171, RGD:4145352, RGD:4145334, RGD:4144228 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 no_association IEP
IAGP
ISO		 Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
DNA:snp:cds:p.L412F (human)		 RGD PMID:21129050 PMID:14987294 PMID:17610940 PMID:21364926 PMID:17434873 RGD:5129226, RGD:5129493, RGD:5129475, RGD:5128500, RGD:5129478 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 susceptibility
no_association
severity		 IAGP
ISO
IEP		 DNA:Polymorphism:cds:p.D299G (human)
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:SNPs::
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)		 RGD PMID:15356557 PMID:20628601 PMID:19067129 PMID:19330007 PMID:19159017 More... RGD:4144817, RGD:4144176, RGD:4144190, RGD:4144141, RGD:4144188, RGD:4144171, RGD:4144198 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 susceptibility IAGP DNA:SNP: :p.S249P (human)
DNA:SNP (human)		 RGD PMID:15266299 PMID:18547625 RGD:4889538, RGD:4889528 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR9 toll like receptor 9 susceptibility
severity
no_association		 IAGP
ISO
IEP		 DNA:SNP:promoter:g.-1237T>C (rs5743836) (human)
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:SNP:promoter:g.-1237T>C rs5743836 (human)		 RGD PMID:18312481 PMID:20016192 PMID:20072849 PMID:21324137 RGD:4144208, RGD:5129104, RGD:4889523, RGD:5130712 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNC tenascin C ISO
EXP
IAGP
IEP		 CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP:exon:p.L1677I (human)
protein:increased expression:bronchus basement membrane		 CTD
RGD		 PMID:16115819 PMID:17125141 PMID:18305139 PMID:16115819 PMID:9310019 RGD:4889565, RGD:4889589, RGD:4889569, RGD:4889572 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor susceptibility
no_association		 IAGP
EXP
ISO
IEP		 associated with obesity; DNA:polymorphism:promoter
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter: c. -308A>G (human)
DNA:polymorphisms:: rs1799964, rs1799724 (human)
DNA:polymorphisms: :
associated with nasal polys; protein:increased expression:nose
DNA:polymorphism:promoter:c.-863C > A (human)		 OMIM
ClinVar
CTD
RGD		 PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143238, RGD:4143443, RGD:4143254, RGD:4143240, RGD:4145508, RGD:4142802, RGD:4143369, RGD:4143372 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 severity EXP
ISO		 CTD Direct Evidence: marker/mechanism
ovalbumin sensitization		 CTD
RGD		 PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584 		JBrowse link
G TSLP thymic stromal lymphopoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
G UCN urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445 		JBrowse link
G UTS2 urotensin 2 IEP RGD PMID:17045018 RGD:2306832 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G VDR vitamin D receptor no_association IAGP DNA:SNPs (human)
DNA:SNP: :rs7975232 (human)
DNA:SNPs: :multiple (human)
DNA:SNP (human)		 RGD PMID:20124605 PMID:19622139 PMID:15282200 PMID:21103062 RGD:4889867, RGD:4889868, RGD:4889854, RGD:4889866 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP
EXP		 protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11907124 PMID:15201500 PMID:19263519 PMID:19178538 RGD:6892723 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:21419198 PMID:16782752 RGD:5685381, RGD:5685620 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
G WDR36 WD repeat domain 36 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 5:111,092,348...111,130,502
Ensembl chr 5:111,092,321...111,130,502 		JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 treatment IEP RGD PMID:30059697 RGD:39939057 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G EPX eosinophil peroxidase IEP protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174 		JBrowse link
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-C major histocompatibility complex, class I, C susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130 		JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP RGD PMID:22397267 RGD:13506905 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr14:23,372,809...23,376,403
Ensembl chr14:23,372,809...23,376,403 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 PMID:21592044 RGD:126928124, RGD:126928124 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility IAGP DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr19:53,991,149...54,012,666
Ensembl chr19:53,991,637...54,012,666 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20485159 PMID:20022477 RGD:4145619 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 IAGP
EXP		 DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16502481 PMID:20485159 PMID:15970796 RGD:5144000 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226 		JBrowse link
G FANCC FA complementation group C IAGP DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 susceptibility IAGP RGD PMID:25975240 RGD:11074090
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 susceptibility IAGP RGD PMID:25975240 RGD:11074090
G IL4 interleukin 4 susceptibility IAGP DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G LOC109286563 TBX21 promoter region IAGP ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chr17:47,731,244...47,733,594 JBrowse link
G LTC4S leukotriene C4 synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467 		JBrowse link
G POSTN periostin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G PTGER2 prostaglandin E receptor 2 IAGP
EXP		 ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:15496426 PMID:16502481 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,329,822 		JBrowse link
G PTGIR prostaglandin I2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,618,550...46,625,089 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEP
EXP		 protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16502481 PMID:20485159 PMID:9487340 RGD:5143936 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member IAGP RGD PMID:21796142 RGD:5147839 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TBX21 T-box transcription factor 21 IAGP
EXP		 ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:15806396 PMID:16502481 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility IAGP
EXP		 DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16502481 PMID:20485159 PMID:15898979 RGD:11059537 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DRA major histocompatibility complex, class II, DR alpha susceptibility IAGP DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G LOC109286563 TBX21 promoter region IAGP ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr17:47,731,244...47,733,594 JBrowse link
G TBX21 T-box transcription factor 21 IAGP ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:25741868 PMID:30643255 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
G LOC109286563 TBX21 promoter region IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chr17:47,731,244...47,733,594 JBrowse link
G LOC130061064 ATAC-STARR-seq lymphoblastoid silent region 8640 IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chr17:47,733,625...47,733,794 JBrowse link
G LTC4S leukotriene C4 synthase IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647 		JBrowse link
G PTGER2 prostaglandin E receptor 2 susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,329,822 		JBrowse link
G TBX21 T-box transcription factor 21 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance		 CTD
OMIM
ClinVar		 PMID:25741868 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha exacerbates IAGP associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
chronic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NGF nerve growth factor treatment ISO RGD PMID:30681402 RGD:405100716 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 severity IEP protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G EPX eosinophil peroxidase treatment IDA RGD PMID:28751233 RGD:13506890 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174 		JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase IMP RGD PMID:10984370 RGD:4890423 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G TACR1 tachykinin receptor 1 IMP RGD PMID:8630576 RGD:5147837 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:5037240, RGD:11251537 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G CDH17 cadherin 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303 		JBrowse link
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr15:28,111,040...28,322,179
Ensembl chr15:28,111,040...28,322,179 		JBrowse link
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:SNP: :rs1811197(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-DOA major histocompatibility complex, class II, DO alpha treatment IAGP DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:33,004,182...33,009,591
Ensembl chr 6:33,004,182...33,009,591 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
G HLA-E major histocompatibility complex, class I, E susceptibility IAGP DNA:SNP: :rs1573294(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G PLA2G4A phospholipase A2 group IVA EXP CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PRKCA protein kinase C alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRKD1 protein kinase D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G TENM3 teneurin transmembrane protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 4:181,447,613...182,803,024
Ensembl chr 4:182,143,987...182,803,024 		JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII IAGP
EXP		 ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL5 interleukin 5 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G MPO myeloperoxidase IEP protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97387
    disease of anatomical entity 91016
      respiratory system disease 16797
        respiratory allergy 1233
          asthma 796
            Asthma and Nasal Polyps 3
            Asthma, Short Stature, and Elevated IgA 0
            Eosinophilic Asthma 2
            Platelet-Activating Factor Acetylhydrolase Deficiency 1
            acute asthma + 5
            atopic dermatitis 3 0
            chronic asthma + 257
Path 2
Term Annotations click to browse term
  disease 97387
    disease of anatomical entity 91016
      Immune & Inflammatory Diseases 18495
        immune system disease 15091
          allergic disease 2234
            Immediate Hypersensitivity 1923
              respiratory allergy 1233
                asthma 796
                  Asthma and Nasal Polyps 3
                  Asthma, Short Stature, and Elevated IgA 0
                  Eosinophilic Asthma 2
                  Platelet-Activating Factor Acetylhydrolase Deficiency 1
                  acute asthma + 5
                  atopic dermatitis 3 0
                  chronic asthma + 257
paths to the root