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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:asthma
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Accession:DOID:2841 term browser browse the term
Definition:A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Synonyms:exact_synonym: AS1;   asthmas;   bronchial asthma
 narrow_synonym: ASTHMA, DIMINISHED RESPONSE TO ANTILEUKOTRIENE TREATMENT IN;   adult onset asthma;   airway hyperresponsiveness
 related_synonym: ASRT1;   ASRT2;   ASRT3;   ASRT4;   ASRT5;   ASRT6;   ASRT7;   ASRT8;   Asthma-Related Traits, Susceptibility To, 1;   Asthma-Related Traits, Susceptibility To, 2;   Asthma-Related Traits, Susceptibility To, 3;   Asthma-Related Traits, Susceptibility To, 4;   Asthma-Related Traits, Susceptibility To, 5;   Asthma-Related Traits, Susceptibility To, 6;   Asthma-Related Traits, Susceptibility To, 7;   Asthma-Related Traits, Susceptibility To, 8;   allergic airway inflammation;   asthma and allergic rhinitis, susceptibility to;   asthma and atopy, susceptibility to;   asthma, protection against;   asthma, susceptibility to;   asthma-traits, susceptibility to asthma, protection against;   beta-2-adrenoreceptor agonist, reduced response to;   childhood athma, susceptibility to;   rhinoconjunctivitis, susceptibility to
 primary_id: MESH:D001249
 alt_id: MIM:600807;   MIM:601690;   MIM:607277;   MIM:608584;   MIM:609958;   MIM:610906;   MIM:611064;   MIM:611403;   MIM:611960;   MIM:613207
 xref: EFO:0000270;   EFO:0005414;   EFO:1002011;   GARD:10246;   ICD10CM:J45;   ICD9CM:493;   MONDO:0004979;   NCI:C28397
For additional species annotation, visit the Alliance of Genome Resources.

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asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:18931056 RGD:5128825 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chrNW_004955453:10,916,423...10,963,986
Ensembl chrNW_004955453:10,913,786...10,947,963 		JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adam33 ADAM metallopeptidase domain 33 susceptibility
no_association
disease_progression		 ISO DNA:polymorphism: :p.M764T (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:SNPs (human)
mRNA:increased expression:lung
DNA:SNPs: :multiple (human)		 RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chrNW_004955415:14,523,517...14,535,701
Ensembl chrNW_004955415:14,524,354...14,533,700 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract		 RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 NCBI chrNW_004955477:10,894,288...10,906,961
Ensembl chrNW_004955477:10,895,446...10,907,215 		JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004955504:4,990,634...5,376,990
Ensembl chrNW_004955504:5,004,903...5,376,328 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chrNW_004955410:32,176,683...32,229,187
Ensembl chrNW_004955410:32,176,536...32,229,431 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402 		JBrowse link
G Adora1 adenosine A1 receptor ISO protein:increased expression:bronchus
DNA:SNPs: :1405C>T (human)		 RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688 		JBrowse link
G Adora2a adenosine A2a receptor ISO DNA:SNP (human)
mRNA:decreased expression:aorta		 RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :-1023A>G (human)		 ClinVar
RGD		 PMID:8383511 PMID:15284533 PMID:16596417 PMID:19638684 RGD:4145081 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980 		JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment
onset		 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)		 RGD
CTD		 PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:19080339 RGD:5147457 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255 		JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chrNW_004955534:3,653,112...3,654,248
Ensembl chrNW_004955534:3,653,157...3,654,248 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:18692885 PMID:19628725 RGD:5509605 RGD:5509784 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
treatment
severity		 ISO DNA:polymorphism:promoter (human)
DNA:repeat:promoter (human)		 RGD
OMIM		 PMID:10369259 PMID:12911785 PMID:16364163 PMID:20128419 RGD:4890407 RGD:4890415 RGD:5147465 RGD:734557 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association
susceptibility		 ISO DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
DNA:SNP: :rs10507391 (human)
DNA:repeat:promoter:-169(A)21 (human)
mRNA:increased expression:blood, leukocyte
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:SNPs (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)		 RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chrNW_004955431:15,071,535...15,097,496
Ensembl chrNW_004955431:15,069,089...15,097,580 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chrNW_004955419:13,478,904...13,492,329
Ensembl chrNW_004955419:13,478,552...13,492,327 		JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chrNW_004955474:680,212...689,021
Ensembl chrNW_004955474:680,204...689,088 		JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung, mononuclear cell (human)
mRNA:increased expression:lung (mouse)
DNA:SNP: :rs2781667 (human)		 CTD
RGD		 PMID:12813022 PMID:19281908 PMID:19800904 PMID:20124949 RGD:4143187 RGD:5129205 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Arg2 arginase 2 susceptibility
severity		 ISO mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
DNA:SNPs (human)
DNA:SNP: :rs3742879, rs17249437 (human)		 RGD
CTD		 PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060 		JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Bdkrb2 bradykinin receptor B2 onset ISO DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil		 RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172 		JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility
severity		 ISO DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
protein:decreased expression:blood, eosinophil
DNA:polymorphisms: :p.V66M, -270C>T (human)
protein:increased expression:plasma
DNA:polymorphisms: :p.V66M (rs6265) (human)		 RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004955405:5,408,171...5,784,930
Ensembl chrNW_004955405:5,700,162...5,787,957 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G C3 complement C3 severity ISO protein:increased expression:serum
Interaction with IL4RA
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :4896C>T (human)
DNA:SNPs: :multiple (human)
DNA:SNP:intron:rs11569562 (human)		 RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G C3ar1 complement C3a receptor 1 severity ISO mRNA:increased expression:lung
protein:increased expression:lung, leukocyte		 RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chrNW_004955413:6,707,003...6,715,689
Ensembl chrNW_004955413:6,707,689...6,715,689 		JBrowse link
G C5ar1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract		 RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chrNW_004955574:1,221,942...1,229,634
Ensembl chrNW_004955574:1,221,187...1,231,655 		JBrowse link
G Card11 caspase recruitment domain family member 11 susceptibility ISO ClinVar Annotator: match by term: Asthma RGD
ClinVar		 PMID:16751370 PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 More... RGD:11100037 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Carm1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004955495:1,983,599...2,002,174
Ensembl chrNW_004955495:1,983,599...2,002,174 		JBrowse link
G Cat catalase severity ISO protein:increased expression:erythrocyte
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-21A>T (human)		 RGD
CTD		 PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chrNW_004955481:9,085,943...9,089,147 JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung		 RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chrNW_004955433:15,052,616...15,054,732
Ensembl chrNW_004955433:15,053,061...15,054,572 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chrNW_004955472:1,444,598...1,446,488
Ensembl chrNW_004955472:1,444,316...1,446,490 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum		 RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion		 RGD PMID:10384142 PMID:15993846 PMID:18316417 PMID:18684970 RGD:2306304 RGD:4145489 RGD:4891474 RGD:4891475 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 susceptibility ISO protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :304C>A, 1272A>G (human)
DNA:SNP: :1265A>G (human)
protein:increased expression:plasma
DNA:SNPs: :179T>C, 275C>T (human)		 RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chrNW_004955456:14,582,812...14,588,574
Ensembl chrNW_004955456:14,583,610...14,585,169 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 treatment ISO DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)		 RGD PMID:15207712 PMID:16304252 PMID:18712274 PMID:25399816 PMID:25530546 RGD:11081163 RGD:11087575 RGD:4891483 RGD:4891495 RGD:5130930 NCBI chrNW_004955456:14,554,583...14,558,967 JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chrNW_004955472:1,470,407...1,474,800
Ensembl chrNW_004955472:1,471,551...1,474,777 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chrNW_004955446:18,902,465...18,925,178
Ensembl chrNW_004955446:18,902,636...18,925,561 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)		 RGD
CTD		 PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 susceptibility ISO protein:increased expression:lung, dendritic cell (mouse)
DNA:haplotype:cds:p.V64I(human)
DNA:SNP:cds:p.V64I (human)		 RGD PMID:17298432 PMID:19917684 PMID:23454776 RGD:4145110 RGD:8549811 RGD:8551842 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)		 RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004955421:205,297...210,944
Ensembl chrNW_004955421:205,297...210,944 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chrNW_004955427:24,646,358...24,690,580
Ensembl chrNW_004955427:24,644,479...24,691,132 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chrNW_004955420:26,083,445...26,093,740
Ensembl chrNW_004955420:26,083,040...26,093,775 		JBrowse link
G Cd14 CD14 molecule severity
no_association
susceptibility		 ISO protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :
DNA:polymorphism:promoter:c. -260C>T (human)		 RGD
CTD		 PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G Cd274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904 		JBrowse link
G Cd28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chrNW_004955427:19,237,251...19,274,001
Ensembl chrNW_004955427:19,236,445...19,261,517 		JBrowse link
G Cd86 CD86 molecule treatment ISO protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
protein:increased expression:lung, alveolar macrophage (mouse)		 RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chrNW_004955484:7,782,409...7,861,082
Ensembl chrNW_004955484:7,782,772...7,860,967 		JBrowse link
G Cdhr3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004955410:10,457,078...10,520,429
Ensembl chrNW_004955410:10,457,072...10,519,826 		JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chrNW_004955432:23,179,645...23,328,347
Ensembl chrNW_004955432:23,178,866...23,328,382 		JBrowse link
G Chat choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chrNW_004955556:650,290...695,135
Ensembl chrNW_004955556:650,279...693,276 		JBrowse link
G Chi3l1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar		 PMID:18403759 NCBI chrNW_004955406:39,195,101...39,201,808
Ensembl chrNW_004955406:39,191,073...39,202,020 		JBrowse link
G Chml CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chrNW_004955406:10,455,367...10,461,934 JBrowse link
G Chrm1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chrNW_004955599:349,744...356,714
Ensembl chrNW_004955599:349,744...356,714 		JBrowse link
G Chrm2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chrNW_004955494:5,845,581...5,975,614
Ensembl chrNW_004955494:5,847,156...5,848,556 		JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chrNW_004955492:958,347...1,429,832
Ensembl chrNW_004955492:958,949...960,721 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chrNW_004955507:6,066,026...6,102,066
Ensembl chrNW_004955507:6,067,203...6,102,001 		JBrowse link
G Clca1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chrNW_004955423:7,684,741...7,714,438
Ensembl chrNW_004955423:7,684,709...7,714,449 		JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chrNW_004955501:962,188...991,922
Ensembl chrNW_004955501:962,188...991,922 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)		 RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chrNW_004955410:31,830,333...31,874,384
Ensembl chrNW_004955410:31,828,506...31,875,100 		JBrowse link
G Csf2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum		 RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chrNW_004955413:23,442,417...23,465,093
Ensembl chrNW_004955413:23,449,111...23,463,820 		JBrowse link
G Csf3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 no_association
severity
treatment		 ISO DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
protein:increased expression:serum
DNA:SNPs: :multiple (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
DNA:SNP: :rs3087243 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-318C>T (human)		 RGD
CTD		 PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460 		JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chrNW_004955425:18,623,645...20,126,200
Ensembl chrNW_004955425:18,628,961...20,087,647 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chrNW_004955433:15,023,272...15,034,650
Ensembl chrNW_004955433:15,023,050...15,034,711 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)		 RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chrNW_004955408:30,733,079...30,740,854
Ensembl chrNW_004955408:30,733,079...30,740,854 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chrNW_004955433:724,566...731,945
Ensembl chrNW_004955433:724,515...732,192 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 severity
susceptibility		 ISO protein:decreased expression:respiratory system fluid/secretion, T cell
DNA:SNP:intron:IVS1+234G>A (human)		 RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chrNW_004955475:11,148,928...11,152,313
Ensembl chrNW_004955475:11,148,879...11,152,596 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 severity
no_association		 ISO DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
mRNA, protein:increased expression:respiratory system mucosa
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNP: :927T>C (human)		 RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16387808 PMID:16630147 More... RGD:4781449 RGD:4781742 RGD:4782072 RGD:4784257 RGD:4843543 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116 NCBI chrNW_004955557:1,667,518...1,702,272 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)		 RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chrNW_004955431:2,203,342...2,282,635
Ensembl chrNW_004955431:2,263,698...2,282,635 		JBrowse link
G Dcn decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chrNW_004955405:28,335,493...28,371,912
Ensembl chrNW_004955405:28,332,545...28,372,323 		JBrowse link
G Dnah5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004955426:3,105,631...3,406,587
Ensembl chrNW_004955426:3,106,410...3,353,502 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:23196709 PMID:23423710 RGD:9588646 NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 ISO DNA:SNP:exon (human)
DNA:SNPs (human)
protein:increased expression:bronchus
DNA:SNP: :rs10208402 (human)		 RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chrNW_004955459:13,456,765...14,767,495
Ensembl chrNW_004955459:13,453,491...14,109,194 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chrNW_004955495:4,609,841...4,615,686 JBrowse link
G Edn1 endothelin 1 ISO DNA:transition:intron:g.4124T>C (human)
CTD Direct Evidence: marker/mechanism
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)		 RGD
CTD		 PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chrNW_004955428:3,062,303...3,114,761
Ensembl chrNW_004955428:3,062,303...3,114,761 		JBrowse link
G Ednrb endothelin receptor type B ISO mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)		 RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chrNW_004955404:29,394,253...29,425,358
Ensembl chrNW_004955404:29,394,164...29,425,358 		JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (rat)
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (mouse)		 RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Egr1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)		 RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chrNW_004955419:18,035,197...18,097,681
Ensembl chrNW_004955419:18,038,507...18,095,894 		JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chrNW_004955520:116,363...142,983
Ensembl chrNW_004955520:116,363...128,665 		JBrowse link
G Epx eosinophil peroxidase severity
disease_progression		 ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946 		JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus		 RGD PMID:21658190 PMID:21711961 RGD:5147753 RGD:5147783 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia severity ISO Asthma symptoms persistent despite steroids
Fatal asthma subjects		 RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chrNW_004955437:3,445,515...3,548,874
Ensembl chrNW_004955437:3,447,075...3,548,564 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Gc GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chrNW_004955435:13,253,947...13,256,965
Ensembl chrNW_004955435:13,253,947...13,256,965 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 severity
disease_progression
no_association
susceptibility		 ISO DNA:SNP: :p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:p.I105V (rs1695) (human)
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)		 RGD
CTD		 PMID:10806136 PMID:11994713 PMID:15693909 PMID:16176403 PMID:16870661 More... RGD:4140946 RGD:4140947 RGD:4140951 RGD:4142519 RGD:4142526 RGD:5490985 RGD:5490991 RGD:5490999 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chrNW_004955408:11,289,920...11,311,216
Ensembl chrNW_004955408:11,291,937...11,311,320 		JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707 		JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chrNW_004955409:4,051,574...4,072,641
Ensembl chrNW_004955409:4,051,271...4,072,642 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chrNW_004955425:25,362,165...25,380,611
Ensembl chrNW_004955425:25,359,884...25,380,745 		JBrowse link
G Hmox1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to RGD
OMIM
ClinVar		 PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 More... RGD:5128885 RGD:5128887 RGD:5128888 NCBI chrNW_004955440:5,084,198...5,137,577
Ensembl chrNW_004955440:5,084,081...5,139,348 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chrNW_004955484:9,206,681...9,212,356
Ensembl chrNW_004955484:9,206,681...9,212,356 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung, serum (rat)
protein:increased secretion:lung (human)		 RGD
CTD		 PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755 		JBrowse link
G Ifng interferon gamma resistance
treatment		 ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chrNW_004955436:22,183,318...22,199,013 JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chrNW_004955451:14,483,669...14,571,108
Ensembl chrNW_004955451:14,484,132...14,536,916 		JBrowse link
G Il10 interleukin 10 treatment
susceptibility		 ISO DNA:polymorphism: :-627C>A (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma		 RGD
CTD		 PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il12a interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chrNW_004955448:10,611,131...10,617,911 JBrowse link
G Il12b interleukin 12B severity
susceptibility		 ISO DNA:polymorphism:promoter
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphisms:introns:
DNA:polymorphisms:promoter, 3'utr:		 RGD
ClinVar		 PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620 		JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism: :c.-1055C>T (human)
protein:increased expression:sputum
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)		 OMIM
ClinVar
RGD		 PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 no_association ISO DNA:polymorphism: :1050C>T (human)
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
mRNA:increased expression:bronchus		 RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655 NCBI chrNW_004955534:1,157,758...1,205,158
Ensembl chrNW_004955534:1,160,340...1,204,911 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum		 RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272 		JBrowse link
G Il15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chrNW_004955471:1,496,352...1,583,919
Ensembl chrNW_004955471:1,497,483...1,511,469 		JBrowse link
G Il16 interleukin 16 severity
no_association		 ISO DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum		 RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chrNW_004955416:11,876,317...11,987,548 JBrowse link
G Il17a interleukin 17A susceptibility ISO mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:alveolar macrophage		 RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17rb interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chrNW_004955430:3,831,665...3,847,366
Ensembl chrNW_004955430:3,831,667...3,846,788 		JBrowse link
G Il18 interleukin 18 susceptibility
severity
disease_progression		 ISO DNA:polymorphism: :c. -105A>C (human)
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
protein:increased expression:serum
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)		 RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)		 RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chrNW_004955470:7,854,995...7,887,810
Ensembl chrNW_004955470:7,854,988...7,887,883 		JBrowse link
G Il19 interleukin 19 ISO protein:increased expression:serum
mRNA, protein:increased expression:lung, serum		 RGD PMID:15557163 RGD:5037236 NCBI chrNW_004955406:42,376,102...42,384,902
Ensembl chrNW_004955406:42,376,104...42,384,902 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO protein:decreased expression:neutrophil
DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1rl1 interleukin 1 receptor like 1 susceptibility
severity		 ISO DNA:SNP: :rs1041973 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1420101 (human)		 RGD
CTD		 PMID:11463601 PMID:17407196 PMID:17623648 PMID:19179489 PMID:19198610 More... RGD:5144235 RGD:5144237 RGD:5144239 RGD:5144240 RGD:5144242 RGD:5144243 RGD:5144244 RGD:5144245 NCBI chrNW_004955470:7,779,828...7,849,157 JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity		 ISO DNA:polymorphism:intron (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2234678 (human)
protein:increased expression:plasma
DNA:SNPs: :rs447713, rs3087271 (human)
DNA:SNPs: :multiple (human)
DNA, protein:repeat, decreased expression (human)		 RGD
CTD		 PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471 		JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
G Il22 interleukin 22 severity
treatment		 ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell		 RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chrNW_004955458:14,747,339...14,755,602
Ensembl chrNW_004955458:14,747,084...14,752,553 		JBrowse link
G Il23r interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904 		JBrowse link
G Il25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chrNW_004955409:36,960,902...36,964,038
Ensembl chrNW_004955409:36,961,398...36,964,038 		JBrowse link
G Il27 interleukin 27 treatment
susceptibility		 ISO protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)		 RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491 NCBI chrNW_004955493:6,712,005...6,717,417
Ensembl chrNW_004955493:6,712,005...6,717,417 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chrNW_004955415:32,749,682...32,762,532
Ensembl chrNW_004955415:32,749,094...32,761,882 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chrNW_004955413:23,623,567...23,640,245
Ensembl chrNW_004955413:23,623,154...23,640,259 		JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease		 CTD
RGD		 PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948 		JBrowse link
G Il4 interleukin 4 no_association
treatment		 ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
DNA:SNP: :589C>T (human)
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism (human)
mRNA:increased expression:lung, spleen
mRNA, protein:increase expression:leukocyte, serum		 RGD
CTD		 PMID:18211752 PMID:18357729 PMID:20524005 PMID:21103062 PMID:21354484 More... RGD:10402791 RGD:10402799 RGD:2317290 RGD:4889866 RGD:5128500 RGD:5128502 RGD:5128557 RGD:5128560 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor disease_progression
susceptibility
severity		 ISO OMIM:600807
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism::-1902G/A (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:SNPs: :multiple
DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:mutation:cds:p.Q576R (mouse)
DNA:SNPs:cds:p. I75V, Q576R (human)		 RGD
MouseDO		 PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Il5 interleukin 5 treatment
disease_progression		 ISO protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-703C>T (human)
protein: increased levels: sputum
protein:increased expression:lungs, respiratory system fluid/secretion		 RGD
CTD		 PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)		 RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chrNW_004955421:10,211,594...10,259,760
Ensembl chrNW_004955421:10,221,694...10,259,885 		JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:lung
associated with Hypersensitivity;protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762 		JBrowse link
G Il9 interleukin 9 ISO protein:increased expression:sputum, macrophage, cytoplasm
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chrNW_004955408:30,950,816...30,953,571
Ensembl chrNW_004955408:30,950,816...30,953,571 		JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chrNW_004955442:17,115,207...17,128,899
Ensembl chrNW_004955442:17,117,429...17,127,451 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar		 PMID:17503328 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Irf1 interferon regulatory factor 1 susceptibility
no_association		 ISO DNA:repeat:intron (human)
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium		 RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973 		JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chrNW_004955559:1,223,986...1,228,671
Ensembl chrNW_004955559:1,224,874...1,228,624 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746 		JBrowse link
G Itgb6 integrin subunit beta 6 ISO OMIM:600807 MouseDO NCBI chrNW_004955449:13,387,013...13,520,879
Ensembl chrNW_004955449:13,448,084...13,520,879 		JBrowse link
G Kdr kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583 		JBrowse link
G Kif3a kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004955408:4,072,823...4,115,975
Ensembl chrNW_004955408:4,069,639...4,115,998 		JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472 		JBrowse link
G Lgals3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G LOC102004444 beta-defensin 1-like susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)		 RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chrNW_004955403:53,643,328...53,644,361
Ensembl chrNW_004955403:53,643,300...53,644,505 		JBrowse link
G LOC102004641 cytochrome b-245 light chain susceptibility ISO DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
DNA:polymorphism: :-930A>G (human)		 RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118 		JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488 		JBrowse link
G LOC102019320 mamu class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chrNW_004955437:1,109,735...1,114,742
Ensembl chrNW_004955437:1,109,713...1,114,802 		JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G LOC102025724 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chrNW_004955437:1,644,037...1,657,094
Ensembl chrNW_004955437:1,643,238...1,651,071 		JBrowse link
G LOC102026028 cytochrome P450 2E1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:leukocyte		 CTD
RGD		 PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 NCBI chrNW_004955507:6,293,162...6,303,255
Ensembl chrNW_004955507:6,289,576...6,304,193 		JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :
DNA:haplotype		 CTD
RGD		 PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:13506911 RGD:5143938 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042 		JBrowse link
G Lta lymphotoxin alpha no_association
susceptibility		 ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter		 RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373 NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chrNW_004955405:32,345,005...32,377,685
Ensembl chrNW_004955405:32,344,925...32,378,384 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:SNP:cds:p.G54D(human)
associated with Bronchiolitis;DNA:polymorphism:exon:		 RGD PMID:22512728 PMID:22674410 RGD:12910828 RGD:8693709 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chrNW_004955442:14,068,436...14,093,889
Ensembl chrNW_004955442:14,068,348...14,094,016 		JBrowse link
G Mif macrophage migration inhibitory factor severity ISO DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter
protein:increased expression:bronchoalveolar lavage fluid		 RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460 		JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004955412:5,965,388...5,976,353
Ensembl chrNW_004955412:5,965,394...5,976,382 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: : rs2664538(human)
protein:increased expression:serum
protein:increased expression:lung
mRNA, protein:increased expression:lung		 CTD
RGD		 PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288 		JBrowse link
G Mpo myeloperoxidase susceptibility ISO protein:increased expression:serum
DNA:polymorphism: :−463G > A (human)		 RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)		 RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chrNW_004955511:4,377,894...4,400,797
Ensembl chrNW_004955511:4,380,502...4,400,852 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chrNW_004955476:11,108,826...11,135,697
Ensembl chrNW_004955476:11,108,826...11,135,697 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment ISO protein:increased expression:lung
mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chrNW_004955476:11,061,405...11,084,294 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11587997 PMID:11802783 RGD:5131252 RGD:7364763 NCBI chrNW_004955476:11,021,665...11,049,239 JBrowse link
G Muc7 mucin 7, secreted ISO ClinVar Annotator: match by term: Asthma, protection against ClinVar
OMIM		 PMID:11378823 PMID:16759176 PMID:28492532 NCBI chrNW_004955447:2,511,841...2,520,312 JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004955439:1,523,516...1,560,185
Ensembl chrNW_004955439:1,521,292...1,560,220 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chrNW_004955427:22,760,432...23,008,432
Ensembl chrNW_004955427:22,762,221...22,970,508 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944 		JBrowse link
G Ngf nerve growth factor severity ISO protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum		 RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:		 RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Nos1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:intron
DNA:repeats:exon
DNA:repeats: :		 RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566 		JBrowse link
G Nos2 nitric oxide synthase 2 no_association
severity
disease_progression		 ISO DNA:repeat:promoter
protein:increased expression, increased activity:lung (rat)
DNA:repeats:promoter, introns (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:p.S608L (human)
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
mRNA:increased expression:monocyte
protein:increased expression:lung, bronchoalveolar lavage fluid		 RGD
CTD		 PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)		 RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814 		JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 OMIM
ClinVar		 PMID:15073379 NCBI chrNW_004955560:1,069,651...1,243,111
Ensembl chrNW_004955560:1,069,651...1,243,111 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
DNA:SNP:exon:c.609C>T (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 severity
susceptibility
treatment		 ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron		 RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 More... RGD:408364991 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221 		JBrowse link
G Ntf3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chrNW_004955413:3,207,669...3,273,371
Ensembl chrNW_004955413:3,207,123...3,273,491 		JBrowse link
G Ntf4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chrNW_004955559:1,647,685...1,650,553
Ensembl chrNW_004955559:1,647,685...1,650,553 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:16708804 PMID:20934630 RGD:5684766 RGD:5684772 NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell		 CTD
RGD		 PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chrNW_004955542:49,290...57,747
Ensembl chrNW_004955542:49,259...58,823 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chrNW_004955423:24,464,503...24,906,409
Ensembl chrNW_004955423:24,463,953...24,906,394 		JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chrNW_004955495:1,250,557...1,261,617
Ensembl chrNW_004955495:1,250,453...1,266,235 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:10733466 RGD:1581025 NCBI chrNW_004955437:11,534,251...11,577,942
Ensembl chrNW_004955437:11,534,173...11,555,996 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:18519237 PMID:21912604 RGD:4892037 NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361 		JBrowse link
G Prf1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chrNW_004955437:20,700,912...20,705,076
Ensembl chrNW_004955437:20,700,718...20,706,929 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004955559:1,205,340...1,215,672
Ensembl chrNW_004955559:1,203,283...1,215,021 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004955407:42,991,305...43,019,332
Ensembl chrNW_004955407:42,992,469...43,018,760 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chrNW_004955476:1,222,579...1,331,582
Ensembl chrNW_004955476:1,223,076...1,331,582 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chrNW_004955409:37,369,507...37,378,034
Ensembl chrNW_004955409:37,369,234...37,378,093 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chrNW_004955459:3,097,229...3,105,566
Ensembl chrNW_004955459:3,094,120...3,104,135 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Ptgdr prostaglandin D2 receptor susceptibility ISO OMIM NCBI chrNW_004955409:10,801,370...10,810,161
Ensembl chrNW_004955409:10,801,328...10,810,066 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chrNW_004955511:5,536,602...5,539,944
Ensembl chrNW_004955511:5,536,642...5,537,926 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity		 ISO mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)		 RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chrNW_004955408:3,953,801...4,035,494
Ensembl chrNW_004955408:3,953,800...4,035,494 		JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chrNW_004955407:34,108,653...34,342,657
Ensembl chrNW_004955407:34,104,035...34,342,928 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO OMIM:600807 MouseDO NCBI chrNW_004955452:4,580,444...4,606,820
Ensembl chrNW_004955452:4,579,331...4,636,884 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to		 RGD
ClinVar		 PMID:9550363 PMID:9643286 PMID:12100044 PMID:21255142 RGD:5144226 NCBI chrNW_004955599:688,414...690,644 JBrowse link
G Scgb3a2 secretoglobin family 3A member 2 susceptibility
no_association
severity		 ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)		 OMIM
ClinVar
RGD		 PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chrNW_004955415:6,332,121...6,335,474
Ensembl chrNW_004955415:6,331,535...6,335,462 		JBrowse link
G Sell selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chrNW_004955462:7,591,997...7,611,408
Ensembl chrNW_004955462:7,591,366...7,612,846 		JBrowse link
G Serpine1 serpin family E member 1 no_association
susceptibility
severity		 ISO DNA:polymorphism:promoter:rs1799768 (human)
protein:increased expression:plasma
protein:increased activity, increased expression:plasma, lung		 RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142 		JBrowse link
G Sftpb surfactant protein B ISO protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell		 RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chrNW_004955424:1,849,313...1,858,087
Ensembl chrNW_004955424:1,849,314...1,858,087 		JBrowse link
G Sftpc surfactant protein C susceptibility ISO DNA:polymorphism: :p.A53T (human)
protein:increased expression:lung
mRNA, protein:decreased expression:lung		 RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chrNW_004955403:45,649,149...45,651,421
Ensembl chrNW_004955403:45,649,122...45,651,837 		JBrowse link
G Sftpd surfactant protein D ISO associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung		 RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chrNW_004955510:213,468...226,096
Ensembl chrNW_004955510:213,438...225,896 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chrNW_004955556:696,779...698,869
Ensembl chrNW_004955556:696,974...698,566 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chrNW_004955470:11,673,491...11,694,404
Ensembl chrNW_004955470:11,673,465...11,697,163 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chrNW_004955481:3,088,440...3,122,421
Ensembl chrNW_004955481:3,088,416...3,125,711 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18211752 PMID:28807506 RGD:2317290 NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:16083555 PMID:19087723 RGD:7244151 RGD:7244153 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
G Tac1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872 		JBrowse link
G Tacr2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chrNW_004955437:21,719,246...21,731,963
Ensembl chrNW_004955437:21,719,246...21,731,963 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chrNW_004955437:1,504,549...1,511,110
Ensembl chrNW_004955437:1,504,947...1,511,097 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism
OMIM:600807		 CTD
MouseDO		 PMID:15806396 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility
severity		 ISO DNA:polymorphism:cds:924T>C(human)
ClinVar Annotator: match by term: Asthma		 RGD
ClinVar		 PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:12000493 More... RGD:11059534 RGD:11059535 NCBI chrNW_004955495:5,539,382...5,557,441
Ensembl chrNW_004955495:5,539,889...5,557,441 		JBrowse link
G Tgfb1 transforming growth factor beta 1 no_association
onset		 ISO DNA:SNP:cds:915G>C (human)
mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
DNA:SNP: :-509C>T (human)
DNA:polymorphisms: :multiple (human)
DNA:SNPs:promoter, exon:multiple (human)
DNA:polymorphism: :-509C>T (human)		 RGD
CTD		 PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813 		JBrowse link
G Tlr1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382 		JBrowse link
G Tlr10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chrNW_004955443:8,442,439...8,468,966
Ensembl chrNW_004955443:8,462,852...8,469,812 		JBrowse link
G Tlr2 toll like receptor 2 susceptibility
severity		 ISO DNA:SNP: :rs7656411 (human)
DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs4696480 (human)
DNA:SNP: :596T>C (human)		 RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 no_association ISO DNA:snp:cds:p.L412F (human)
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)		 RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 susceptibility
severity
no_association		 ISO protein:decreased expression:leukocytes, mononuclear
DNA:Polymorphism:cds:p.D299G (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:SNPs::		 RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 susceptibility ISO DNA:SNP: :p.S249P (human)
DNA:SNP (human)		 RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Tlr9 toll like receptor 9 no_association
susceptibility
severity		 ISO DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
DNA:SNP:promoter:g.-1237T>C (rs5743836) (human)
protein:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:18312481 PMID:20016192 PMID:20072849 PMID:21324137 RGD:4144208 RGD:4889523 RGD:5129104 RGD:5130712 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnc tenascin C ISO protein:increased expression:bronchus basement membrane
DNA:SNPs: :multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:p.L1677I (human)		 RGD
CTD		 PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chrNW_004955419:12,569,620...12,662,897
Ensembl chrNW_004955419:12,569,547...12,662,958 		JBrowse link
G Tnf tumor necrosis factor no_association
susceptibility		 ISO DNA:polymorphism:promoter:
ClinVar Annotator: match by term: Asthma, susceptibility to		 RGD
OMIM
ClinVar		 PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143254 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chrNW_004955408:2,575,324...2,621,845
Ensembl chrNW_004955408:2,594,756...2,621,304 		JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization		 CTD
RGD		 PMID:19458046 PMID:31969645 RGD:127285811 NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372 		JBrowse link
G Tslp thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chrNW_004955418:4,041,529...4,045,534 JBrowse link
G Ucn urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641 		JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chrNW_004955486:5,052,045...5,056,610
Ensembl chrNW_004955486:5,052,045...5,056,610 		JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs: :multiple (human)
DNA:SNPs (human)
DNA:SNP (human)
DNA:SNP: :rs7975232 (human)		 RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:sputum		 CTD
RGD		 PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792 		JBrowse link
G Wdr36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chrNW_004955418:3,988,073...4,023,425
Ensembl chrNW_004955418:3,988,073...4,023,974 		JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643 		JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chrNW_004955456:14,554,583...14,558,967 JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chrNW_004955557:1,667,518...1,702,272 JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chrNW_004955409:36,960,902...36,964,038
Ensembl chrNW_004955409:36,961,398...36,964,038 		JBrowse link
G LOC102025724 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004955437:1,644,037...1,657,094
Ensembl chrNW_004955437:1,643,238...1,651,071 		JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042 		JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chrNW_004955604:189,261...205,058
Ensembl chrNW_004955604:185,430...205,088 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:20022477 PMID:20485159 RGD:4145619 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chrNW_004955557:1,667,518...1,702,272 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)		 CTD
RGD		 PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chrNW_004955431:2,203,342...2,282,635
Ensembl chrNW_004955431:2,263,698...2,282,635 		JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chrNW_004955422:22,031,825...22,246,478
Ensembl chrNW_004955422:22,032,258...22,247,044 		JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chrNW_004955408:788,856...791,505 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004955511:4,377,894...4,400,797
Ensembl chrNW_004955511:4,380,502...4,400,852 		JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chrNW_004955431:8,510,646...8,544,901
Ensembl chrNW_004955431:8,510,624...8,544,971 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004955511:5,536,602...5,539,944
Ensembl chrNW_004955511:5,536,642...5,537,926 		JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chrNW_004955409:10,760,801...10,775,197
Ensembl chrNW_004955409:10,757,888...10,774,688 		JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004955574:686,156...690,126
Ensembl chrNW_004955574:687,583...689,750 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chrNW_004955437:1,480,217...1,499,032
Ensembl chrNW_004955437:1,477,341...1,498,575 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chrNW_004955495:5,539,382...5,557,441
Ensembl chrNW_004955495:5,539,889...5,557,441 		JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102019320 mamu class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chrNW_004955437:1,109,735...1,114,742
Ensembl chrNW_004955437:1,109,713...1,114,802 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:25741868 PMID:30643255 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Ltc4s leukotriene C4 synthase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chrNW_004955408:788,856...791,505 JBrowse link
G Ptger2 prostaglandin E receptor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chrNW_004955409:10,760,801...10,775,197
Ensembl chrNW_004955409:10,757,888...10,774,688 		JBrowse link
G Tbx21 T-box transcription factor 21 susceptibility ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar
OMIM		 PMID:25741868 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
chronic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngf nerve growth factor treatment ISO RGD PMID:30681402 RGD:405100716 NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059 		JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 severity ISO protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chrNW_004955456:14,554,583...14,558,967 JBrowse link
G Epx eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872 		JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chrNW_004955453:10,916,423...10,963,986
Ensembl chrNW_004955453:10,913,786...10,947,963 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Cd86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389 		JBrowse link
G Il23a interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312 		JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
G Cdh17 cadherin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004955417:10,370,606...10,441,008
Ensembl chrNW_004955417:10,370,471...10,441,128 		JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004955533:1,304,675...1,489,041
Ensembl chrNW_004955533:1,304,675...1,489,041 		JBrowse link
G LOC102025166 HLA class II histocompatibility antigen, DO alpha chain treatment ISO DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004955437:1,603,395...1,606,800
Ensembl chrNW_004955437:1,603,168...1,607,134 		JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206 		JBrowse link
G Prkca protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004955478:5,686,639...6,090,356
Ensembl chrNW_004955478:5,686,640...6,083,967 		JBrowse link
G Prkd1 protein kinase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Tenm3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chrNW_004955403:25,920,919...26,534,817
Ensembl chrNW_004955403:25,923,750...26,365,894 		JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII ISO ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency ClinVar
OMIM		 PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chrNW_004955437:11,534,251...11,577,942
Ensembl chrNW_004955437:11,534,173...11,555,996 		JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14316
    disease of anatomical entity 14023
      respiratory system disease 4552
        respiratory allergy 334
          asthma 303
            Asthma and Nasal Polyps 2
            Asthma, Short Stature, and Elevated IgA 0
            Eosinophilic Asthma 2
            Platelet-Activating Factor Acetylhydrolase Deficiency 1
            acute asthma + 5
            atopic dermatitis 3 0
            chronic asthma + 44
Path 2
Term Annotations click to browse term
  disease 14316
    disease of anatomical entity 14023
      Immune & Inflammatory Diseases 4827
        immune system disease 4289
          allergic disease 526
            Immediate Hypersensitivity 404
              respiratory allergy 334
                asthma 303
                  Asthma and Nasal Polyps 2
                  Asthma, Short Stature, and Elevated IgA 0
                  Eosinophilic Asthma 2
                  Platelet-Activating Factor Acetylhydrolase Deficiency 1
                  acute asthma + 5
                  atopic dermatitis 3 0
                  chronic asthma + 44
paths to the root