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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:asthma
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Accession:DOID:2841 term browser browse the term
Definition:A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Synonyms:exact_synonym: AS1;   asthmas;   bronchial asthma
 narrow_synonym: ASTHMA, DIMINISHED RESPONSE TO ANTILEUKOTRIENE TREATMENT IN
 related_synonym: ASRT1;   ASRT2;   ASRT3;   ASRT4;   ASRT5;   ASRT6;   ASRT7;   ASRT8;   Asthma-Related Traits, Susceptibility To, 1;   Asthma-Related Traits, Susceptibility To, 2;   Asthma-Related Traits, Susceptibility To, 3;   Asthma-Related Traits, Susceptibility To, 4;   Asthma-Related Traits, Susceptibility To, 5;   Asthma-Related Traits, Susceptibility To, 6;   Asthma-Related Traits, Susceptibility To, 7;   Asthma-Related Traits, Susceptibility To, 8;   allergic airway inflammation;   asthma and allergic rhinitis, susceptibility to;   asthma and atopy, susceptibility to;   asthma, protection against;   asthma, susceptibility to;   asthma-traits, susceptibility to asthma, protection against;   beta-2-adrenoreceptor agonist, reduced response to;   childhood athma, susceptibility to;   rhinoconjunctivitis, susceptibility to
 primary_id: MESH:D001249
 alt_id: OMIM:600807;   OMIM:601690;   OMIM:607277;   OMIM:608584;   OMIM:609958;   OMIM:610906;   OMIM:611064;   OMIM:611403;   OMIM:611960;   OMIM:613207
 xref: GARD:10246;   ICD10CM:J45;   ICD9CM:493;   NCI:C28397
For additional species annotation, visit the Alliance of Genome Resources.



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asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 ISO RGD PMID:18931056 RGD:5128825
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:16008680 PMID:19771478 RGD:5128831 RGD:5128835 NCBI chr 9:104,354,115...104,399,057
Ensembl chr 9:132,989,574...133,010,324
JBrowse link
G ACE angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19383228 PMID:19484664 RGD:4140913 RGD:4140919 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr2B:110,100,210...110,181,277
Ensembl chr2B:228,706,142...228,759,882
JBrowse link
G ADA adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 disease_progression
no_association
susceptibility
ISO DNA:SNPs (human)
mRNA:increased expression:bronchus
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:lung
DNA:SNPs: :multiple (human)
DNA:polymorphism: :p.M764T (human)
RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chr20:3,750,158...3,764,262
Ensembl chr20:3,508,620...3,521,628
JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 Ensembl chr10:134,172,724...134,186,227 JBrowse link
G ADCY2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:7,718,581...8,154,006
Ensembl chr 5:7,540,790...7,975,853
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 7:31,597,251...31,724,299
Ensembl chr 7:31,784,622...31,843,381
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO DNA:SNPs: :rs1154404, rs28730619 (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128882 RGD:5128890 RGD:5128891 RGD:5128892 NCBI chr 4:91,470,304...91,487,854
Ensembl chr 4:102,134,375...102,151,902
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G ADORA1 adenosine A1 receptor ISO protein:increased expression:bronchus
DNA:SNPs: :1405C>T (human)
RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760
JBrowse link
G ADORA2A adenosine A2a receptor ISO DNA:SNP (human)
mRNA:decreased expression:aorta
RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189
JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to OMIM
ClinVar
PMID:8383511 PMID:15284533 PMID:16596417 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
onset
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
RGD
CTD
PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:19080339 RGD:5147457 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:18692885 PMID:19628725 RGD:5509605 RGD:5509784 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase susceptibility
severity
treatment
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.E254K (human)
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:promoter (human)
mRNA:increased expression:blood, leukocyte
OMIM
RGD
CTD
PMID:8879219 PMID:9642160 PMID:10369259 PMID:11035107 PMID:12911785 More... RGD:4890407 RGD:4890408 RGD:4890410 RGD:4890413 RGD:4890415 RGD:4890422 RGD:5147462 RGD:5147465 RGD:5147467 RGD:734557 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association
susceptibility
ISO DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:SNPs (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)
DNA:SNP: :rs10507391 (human)
RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chr13:12,012,399...12,041,557
Ensembl chr13:30,425,510...30,476,607
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 9:85,157,680...85,176,253
Ensembl chr 9:113,525,835...113,543,422
JBrowse link
G ANG angiogenin severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 4:49,737,191...49,747,013
Ensembl chr 4:55,570,299...55,580,142
JBrowse link
G ARG1 arginase 1 ISO mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2781667 (human)
mRNA, protein:increased expression:lung, mononuclear cell (human)
RGD
CTD
PMID:12813022 PMID:19281908 PMID:19800904 PMID:20124949 RGD:4143187 RGD:5129205 NCBI chr 6:129,372,747...129,383,880
Ensembl chr 6:133,479,966...133,491,162
JBrowse link
G ARG2 arginase 2 susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs (human)
DNA:SNP: :rs3742879, rs17249437 (human)
mRNA:increased expression:lung (mouse)
CTD
RGD
PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BDKRB2 bradykinin receptor B2 onset ISO DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil
RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G BDNF brain derived neurotrophic factor susceptibility
severity
ISO DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
protein:decreased expression:blood, eosinophil
DNA:polymorphisms: :p.V66M (rs6265) (human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
protein:increased expression:plasma
RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 4:87,125,911...87,523,084
Ensembl chr 4:98,088,072...98,195,848
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G C3 complement C3 severity ISO Interaction with IL4RA
DNA:SNP: :4896C>T (human)
DNA:SNP:intron:rs11569562 (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :multiple (human)
protein:increased expression:serum
RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C3AR1 complement C3a receptor 1 severity ISO mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G C5 complement C5 severity ISO mRNA:decreased expression:lung RGD PMID:10973279 PMID:11591795 PMID:15278436 PMID:20143644 PMID:20802484 RGD:1600651 RGD:5129512 RGD:5129681 RGD:5129706 RGD:5130158 NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856
JBrowse link
G C5AR1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146
JBrowse link
G CARD11 caspase recruitment domain family member 11 susceptibility ISO ClinVar Annotator: match by term: Asthma RGD
ClinVar
PMID:16751370 PMID:18323416 PMID:23129749 PMID:25741868 PMID:28492532 RGD:11100037 NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:10,424,993...10,476,702
Ensembl chr19:11,144,733...11,195,948
JBrowse link
G CASP1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149
JBrowse link
G CAT catalase severity ISO protein:decreased activity:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-21A>T (human)
protein:increased expression:erythrocyte
DNA:polymorphism:promoter:-262C>T (human)
RGD
CTD
PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr17:22,425,022...22,430,243
Ensembl chr17:22,719,425...22,722,341
JBrowse link
G CCL11 C-C motif chemokine ligand 11 susceptibility
severity
ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
OMIM
RGD
CTD
PMID:16304252 PMID:20704746 RGD:4145387 RGD:5130930 NCBI chr17:22,495,737...22,515,144
Ensembl chr17:22,806,076...22,808,345
Ensembl chr17:22,806,076...22,808,345
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chr16:37,678,518...37,689,350
Ensembl chr16:56,819,949...56,822,131
JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment
severity
ISO mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
protein:increased expression:lung
RGD
CTD
PMID:12055264 PMID:17964702 PMID:19373627 PMID:20205697 PMID:23454776 More... RGD:11528569 RGD:11528570 RGD:2307055 RGD:4145509 RGD:4891466 RGD:8551842 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung
RGD PMID:10384142 PMID:15993846 PMID:18316417 PMID:18684970 RGD:2306304 RGD:4145489 RGD:4891474 RGD:4891475 NCBI chr16:37,631,861...37,640,208
Ensembl chr16:56,765,367...56,771,213
JBrowse link
G CCL24 C-C motif chemokine ligand 24 susceptibility ISO DNA:SNPs: :179T>C, 275C>T (human)
protein:increased expression:plasma
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
DNA:SNPs: :304C>A, 1272A>G (human)
RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chr 7:68,206,688...68,210,343
Ensembl chr 7:82,263,310...82,265,480
JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment ISO protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
RGD PMID:15207712 PMID:16304252 PMID:18712274 PMID:25399816 PMID:25530546 RGD:11081163 RGD:11087575 RGD:4891483 RGD:4891495 RGD:5130930 NCBI chr 7:68,230,804...68,251,369
Ensembl chr 7:82,221,846...82,242,874
JBrowse link
G CCL27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chr 9:34,498,478...34,501,475
Ensembl chr 9:35,307,175...35,308,146
JBrowse link
G CCL28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 5:66,977,643...66,998,420
Ensembl chr 5:72,012,579...72,046,031
JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO DNA:transition:5' utr:-403G>A (human)
protein:increased expression:smooth muscle cell
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172
JBrowse link
G CCR1 C-C motif chemokine receptor 1 severity ISO associated with Respiratory Syncytial Virus Infections
mRNA:increased expression:lung
RGD PMID:15593301 PMID:15654816 RGD:5688158 RGD:5688159 NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755
JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility ISO DNA:haplotype:cds:p.V64I(human)
DNA:SNP:cds:p.V64I (human)
protein:increased expression:lung, dendritic cell (mouse)
RGD PMID:17298432 PMID:19917684 PMID:23454776 RGD:4145110 RGD:8549811 RGD:8551842 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO DNA:SNP:exon:51T>C (human)
protein:increased expression:respiratory system fluid/secretion, neutrophil
RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:32,882,419...32,887,442
Ensembl chr 3:33,188,482...33,189,564
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO protein:decreased expression:blood, lymphocyte (human)
mRNA:increased expression:lung (mouse)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:15256090 PMID:16474097 PMID:18094012 PMID:20220260 PMID:23454776 RGD:4145638 RGD:4892088 RGD:4892093 RGD:4892108 RGD:8551842 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779
JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr17:16,720,236...16,731,955
Ensembl chr17:16,949,119...16,956,370
JBrowse link
G CCR8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:39,232,185...39,236,157 JBrowse link
G CCR9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 3:45,719,655...45,810,964
Ensembl chr 3:46,900,845...46,917,443
JBrowse link
G CD14 CD14 molecule susceptibility
severity
no_association
ISO DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)
protein:increased expression:serum
DNA:SNPs: :
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
RGD
CTD
PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chr 5:135,996,265...135,997,909
Ensembl chr 5:142,113,082...142,118,966
JBrowse link
G CD1D CD1d molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 1:133,549,258...133,557,752
Ensembl chr 1:137,341,690...137,348,173
JBrowse link
G CD274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 9:5,269,270...5,289,629
Ensembl chr 9:5,454,391...5,474,402
JBrowse link
G CD28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chr 3:116,646,590...116,683,725
Ensembl chr 3:123,559,559...123,594,870
JBrowse link
G CD86 CD86 molecule treatment ISO DNA:snp:exon:p.I179V rs2681417 (human)
protein:increased expression:lung, dendritic cell (rat)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, alveolar macrophage (mouse)
RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
G CDH1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488
JBrowse link
G CDHR3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 7:97,939,965...98,021,172
Ensembl chr 7:110,687,853...110,745,227
JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864
JBrowse link
G CHAT choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr10:44,574,925...44,629,618 JBrowse link
G CHI3L1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar
PMID:18403759 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229
JBrowse link
G CHIA chitinase acidic no_association ISO DNA:snps:5' utr, cds:multiple (human)
mRNA:increased expression:lung (mouse)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
RGD PMID:14734765 PMID:15192232 PMID:16179638 PMID:19548841 PMID:20226308 RGD:4985150 RGD:4990463 RGD:4996473 RGD:5024921 RGD:5024922 NCBI chr 1:113,935,888...113,965,541
Ensembl chr 1:126,381,724...126,391,909
JBrowse link
G CHML CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chr 1:217,191,065...217,202,578 JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chr10:96,794,228...96,835,449
Ensembl chr10:100,280,490...100,316,918
JBrowse link
G CLCA1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chr 1:118,999,099...119,030,839
Ensembl chr 1:87,852,599...87,884,751
JBrowse link
G CLDN18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 3:135,037,555...135,061,105
Ensembl chr 3:142,478,031...142,512,548
JBrowse link
G CMA1 chymase 1 susceptibility
severity
no_association
ISO DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
protein:increased expression:lung epithelium, mast cell (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
RGD PMID:15248847 PMID:15924217 PMID:20813890 RGD:1625396 RGD:1625397 RGD:5128804 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
DNA:SNP: :RS242941 (human)
RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220
JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CSF2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146
JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chr22:17,831,313...17,858,272
Ensembl chr22:35,666,734...35,693,701
JBrowse link
G CSF3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 severity
no_association
treatment
ISO DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:SNPs: :multiple (human)
protein:increased expression:serum
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498
JBrowse link
G CTNNA3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr10:62,388,454...64,177,116
Ensembl chr10:64,712,576...66,442,238
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:polymorphisms: :p.V249I, p.T280M (human)
DNA:SNPs: :p.V249I, rs2669849 (human)
RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr 5:130,960,143...130,967,365
Ensembl chr 5:137,100,019...137,108,336
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO mRNA:increased expression:bronchus epithelium RGD PMID:17234659 RGD:5135243 NCBI chr 4:50,192,665...50,195,642
Ensembl chr 4:56,024,848...56,027,989
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO RGD PMID:9620668 RGD:5135265 NCBI chr 4:50,357,643...50,359,822
Ensembl chr 4:56,189,961...56,192,402
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr 4:48,198,478...48,204,658
Ensembl chr 4:54,036,342...54,042,502
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 severity
susceptibility
ISO protein:decreased expression:respiratory system fluid/secretion, T cell
DNA:SNP:intron:IVS1+234G>A (human)
RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chr  X:60,880,759...60,883,355
Ensembl chr  X:70,933,160...70,935,756
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 no_association
severity
ISO DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNPs:promoter, exon:multiple (human)
RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16387808 PMID:16630147 More... RGD:4781449 RGD:4781742 RGD:4782072 RGD:4784257 RGD:4843543 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116 NCBI chr  X:67,412,410...67,469,366
Ensembl chr  X:77,524,455...77,525,468
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chr13:29,796,598...29,853,676
Ensembl chr13:48,551,757...48,552,797
JBrowse link
G DCN decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr12:88,678,791...88,715,677
Ensembl chr12:91,994,129...92,031,413
JBrowse link
G DEFB1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chr 8:403,268...410,712
Ensembl chr 8:6,874,235...6,881,631
JBrowse link
G DNAH5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:13,989,114...14,316,855
Ensembl chr 5:13,851,391...14,093,358
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD
RGD
PMID:23196709 PMID:23423710 RGD:9588646 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DPP10 dipeptidyl peptidase like 10 ISO DNA:SNPs (human)
DNA:SNP: :rs10208402 (human)
DNA:SNP:exon (human)
protein:increased expression:bronchus
RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chr2B:1,373,640...2,775,574
Ensembl chr2B:114,920,488...116,362,960
JBrowse link
G EBI3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr19:3,252,194...3,266,893
Ensembl chr19:4,199,983...4,205,825
JBrowse link
G EDN1 endothelin 1 ISO Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)
RGD
CTD
PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545
JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497
JBrowse link
G EDNRB endothelin receptor type B ISO mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)
RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chr13:59,112,349...59,136,615
Ensembl chr13:78,153,020...78,177,286
JBrowse link
G EGFR epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (rat)
protein:increased expression:lung epithelium (mouse)
protein:increased expression:bronchial epithelium (human)
RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EGR1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)
RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chr 9:80,020,131...80,085,076
Ensembl chr 9:108,194,011...108,258,500
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
G EPX eosinophil peroxidase disease_progression
severity
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chr17:52,269,114...52,281,471
Ensembl chr17:57,124,924...57,136,992
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G F2 coagulation factor II, thrombin ISO associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
protein:increased expression:plasma
RGD PMID:21658190 PMID:21711961 RGD:5147753 RGD:5147783 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia severity ISO Fatal asthma subjects
Asthma symptoms persistent despite steroids
RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chr 1:137,074,342...137,090,962
Ensembl chr 1:140,882,043...140,890,637
JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FKBP5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr 6:35,135,745...35,250,860
Ensembl chr 6:36,337,883...36,452,664
JBrowse link
G FOXP3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G GATA3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G GC GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073
JBrowse link
G GSDMB gasdermin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr17:17,370,351...17,384,639
Ensembl chr17:17,590,018...17,604,177
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
resistance
ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11075422 PMID:16870661 PMID:17651144 PMID:18988661 PMID:21051083 RGD:4140921 RGD:4142509 RGD:5490962 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G GSTM3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr 1:112,380,890...112,384,988
Ensembl chr 1:127,957,008...127,960,578
JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr10:100,868,109...100,901,013
Ensembl chr10:104,326,175...104,357,604
JBrowse link
G GSTP1 glutathione S-transferase pi 1 no_association
severity
susceptibility
disease_progression
ISO DNA:SNPs: :p.I105V, p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :p.A114V (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:polymorphism:exon:p.I105V (rs1695) (human)
RGD
CTD
PMID:10806136 PMID:11994713 PMID:15693909 PMID:16176403 PMID:16870661 More... RGD:4140946 RGD:4140947 RGD:4140951 RGD:4142519 RGD:4142526 RGD:5490985 RGD:5490991 RGD:5490999 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr 5:152,429,337...152,459,800
Ensembl chr 5:158,413,073...158,442,481
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr 5:152,486,125...152,514,004
Ensembl chr 5:159,108,915...159,131,007
JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004
JBrowse link
G HDC histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr15:29,188,296...29,212,327
Ensembl chr15:47,510,629...47,534,577
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785
JBrowse link
G HMOX1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HNMT histamine N-methyltransferase susceptibility
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to OMIM
ClinVar
RGD
PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 RGD:5128885 RGD:5128887 RGD:5128888 NCBI chr2B:21,840,342...21,892,744
Ensembl chr2B:142,036,321...142,088,315
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr16:47,776,118...47,782,861
Ensembl chr16:67,165,215...67,171,417
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)
mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IFNG interferon gamma treatment
resistance
ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chr 6:134,958,270...134,980,560
Ensembl chr 6:139,045,821...139,068,053
JBrowse link
G IL10 interleukin 10 susceptibility
treatment
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma
DNA:polymorphism: :-627C>A (human)
CTD
RGD
PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL12A interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chr 3:157,011,675...157,019,897
Ensembl chr 3:165,061,505...165,068,666
JBrowse link
G IL12B interleukin 12B susceptibility
severity
ISO DNA:polymorphisms:promoter, 3'utr:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter
DNA:polymorphisms:introns:
RGD
ClinVar
PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381
JBrowse link
G IL13 interleukin 13 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
protein:increased expression:sputum
DNA:polymorphism: :c.-1055C>T (human)
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)
OMIM
ClinVar
RGD
PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 no_association ISO mRNA:increased expression:bronchus
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1050C>T (human)
RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655 NCBI chr  X:107,735,233...107,813,282
Ensembl chr  X:118,202,285...118,266,770
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum
RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chr  X:104,092,993...104,146,062
Ensembl chr  X:114,597,077...114,635,253
JBrowse link
G IL15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chr 4:133,693,995...134,115,470
Ensembl chr 4:145,402,111...145,416,622
JBrowse link
G IL16 interleukin 16 no_association
severity
ISO DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum
RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chr15:60,181,827...60,299,406
Ensembl chr15:79,122,988...79,250,861
JBrowse link
G IL17A interleukin 17A susceptibility ISO DNA:SNP:promoter:rs2275913 (human)
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
protein:increased expression:alveolar macrophage
RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074
JBrowse link
G IL17RB interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr 3:53,784,489...53,803,834
Ensembl chr 3:55,005,499...55,024,763
JBrowse link
G IL18 interleukin 18 susceptibility
disease_progression
severity
ISO DNA:polymorphism: :c. -105A>C (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
protein:increased expression:serum
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)
RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chr2A:99,419,686...99,462,650 JBrowse link
G IL19 interleukin 19 ISO mRNA, protein:increased expression:lung, serum
protein:increased expression:serum
RGD PMID:15557163 RGD:5037236 NCBI chr 1:182,372,339...182,446,147
Ensembl chr 1:186,651,640...186,724,748
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta susceptibility ISO DNA:polymorphism: :-511C>T (human)
protein:decreased expression:neutrophil
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915
JBrowse link
G IL22 interleukin 22 severity
treatment
ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell
RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chr12:65,757,069...65,762,418
Ensembl chr12:68,542,076...68,547,421
JBrowse link
G IL23R interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 1:66,408,839...66,502,535
Ensembl chr 1:68,293,514...68,386,815
JBrowse link
G IL25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr14:4,191,888...4,195,043
Ensembl chr14:22,286,347...22,289,498
JBrowse link
G IL27 interleukin 27 treatment
susceptibility
ISO protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)
RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 Ensembl chr19:14,323,618...14,343,627 JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chr10:6,053,549...6,103,863 JBrowse link
G IL2RB interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chr22:18,039,469...18,069,952
Ensembl chr22:35,874,898...35,899,038
JBrowse link
G IL3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)
RGD PMID:15372320 PMID:24684517 RGD:13506914 RGD:13506916 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G IL32 interleukin 32 ISO protein:increased expression:blood serum (human) RGD PMID:22336080 RGD:150340749 NCBI chr16:2,007,018...2,023,757
Ensembl chr16:3,179,637...3,203,929
JBrowse link
G IL33 interleukin 33 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624
JBrowse link
G IL4 interleukin 4 no_association
treatment
ISO DNA:polymorphism (human)
DNA:SNP: :589C>T (human)
mRNA, protein:increase expression:leukocyte, serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung, spleen
protein:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD
CTD
PMID:18211752 PMID:18357729 PMID:20524005 PMID:21103062 PMID:21354484 More... RGD:10402791 RGD:10402799 RGD:2317290 RGD:4889866 RGD:5128500 RGD:5128502 RGD:5128557 RGD:5128560 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL4R interleukin 4 receptor susceptibility
disease_progression
severity
ISO DNA:polymorphism:cds:p. S478P (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:mutation:cds:p.Q576R (mouse)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism:promoter:c.-3223C>T (human)
RGD PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL5 interleukin 5 disease_progression
treatment
ISO protein:increased expression:lungs, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
protein: increased levels: sputum
DNA:polymorphism:promoter:-703C>T (human)
RGD
CTD
PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
JBrowse link
G IL5RA interleukin 5 receptor subunit alpha ISO DNA:SNPs (human)
DNA:SNP: :c.25091G>A (human)
RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chr 3:3,009,780...3,051,604
Ensembl chr 3:3,112,355...3,156,282
JBrowse link
G IL6 interleukin 6 ISO associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G IL9 interleukin 9 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chr 5:131,283,170...131,289,777
Ensembl chr 5:137,425,367...137,428,945
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar
PMID:17503328 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148
JBrowse link
G IRF1 interferon regulatory factor 1 no_association
susceptibility
ISO DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)
RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035
JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr19:46,674,193...46,680,464
Ensembl chr19:55,593,627...55,599,903
JBrowse link
G ITGB3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811
JBrowse link
G KDR kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G KIF3A kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:128,112,636...128,154,443
Ensembl chr 5:134,274,352...134,315,431
JBrowse link
G KRT19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr17:15,788,355...15,793,127
Ensembl chr17:16,006,608...16,010,782
JBrowse link
G LEP leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LGALS3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain no_association
disease_progression
susceptibility
ISO DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :
Alternaria sensitive asthma
RGD
CTD
PMID:10792356 PMID:11802952 PMID:12890388 PMID:19052351 PMID:20159242 More... RGD:13506906 RGD:13506913 RGD:4144113 RGD:4144181 RGD:5147617 RGD:5147799 RGD:5147831 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G LOC100973583 HLA class II histocompatibility antigen, DQ alpha 2 chain susceptibility ISO DNA:polymorphism: :rs3916765(human) RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,314,091...32,319,909
Ensembl chr 6:33,429,832...33,435,363
JBrowse link
G LOC100975642 zinc finger protein Aiolos ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr17:17,459,438...17,498,452
Ensembl chr17:17,643,750...17,741,479
JBrowse link
G LOC100976419 interferon lambda-1 exacerbates ISO associated with common cold;protein:increased expression: nasal cavity (human)
associated with common cold;mRNA:decreased expression:sputum (human)
RGD PMID:22135341 PMID:25784275 RGD:126848770 RGD:126848775 NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519
JBrowse link
G LOC100977568 tenascin ISO protein:increased expression:bronchus basement membrane
DNA:SNP:exon:p.L1677I (human)
DNA:SNPs: :multiple (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chr 9:86,125,672...86,222,804
Ensembl chr 9:114,486,778...114,584,299
JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G LOC100986914 cytochrome b-245 light chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719
JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNPs: :rs447713, rs3087271 (human)
DNA:SNP: :rs2234678 (human)
DNA:polymorphism:intron (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
RGD
CTD
PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LOC100991889 interleukin-9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr 9:109,268,011...109,277,418
Ensembl chr  X:155,373,324...155,386,631
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphisms: :
DNA:haplotype
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:13506911 RGD:5143938 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G LOC100995577 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr 6:32,637,826...32,646,501
Ensembl chr 6:33,752,638...33,761,417
JBrowse link
G LOC103785360 neurotrophin-4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr19:46,041,053...46,041,808
Ensembl chr19:54,995,009...54,995,641
JBrowse link
G LTA lymphotoxin alpha susceptibility
no_association
ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter
RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373 NCBI chr 6:31,233,411...31,235,409
Ensembl chr 6:32,123,353...32,125,375
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr12:93,589,758...93,624,529
Ensembl chr12:96,978,203...97,012,427
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:12910828 RGD:8693709 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr16:2,175,858...2,191,056
Ensembl chr16:3,353,666...3,368,970
JBrowse link
G MIF macrophage migration inhibitory factor severity ISO protein:increased expression:bronchoalveolar lavage fluid
DNA:repeats:promoter
DNA:SNP:promoter:rs755622(human)
RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr11:97,710,819...97,721,263
Ensembl chr11:101,201,665...101,212,103
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:serum
protein:increased expression:lung
DNA:SNP: : rs2664538(human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung
RGD
CTD
PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase susceptibility ISO protein:increased expression:serum
DNA:polymorphism: :−463G > A (human)
RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chr11:55,318,843...55,326,779
Ensembl chr11:58,764,911...58,772,567
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MUC1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chr11:1,106,716...1,144,489
Ensembl chr11:1,143,625...1,169,741
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment ISO mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chr11:1,191,223...1,234,373 JBrowse link
G MUC7 mucin 7, secreted susceptibility ISO ClinVar Annotator: match by term: Asthma, protection against OMIM
ClinVar
PMID:11378823 PMID:16759176 NCBI chr 4:53,741,379...53,750,277 JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 6:132,952,728...132,990,560
Ensembl chr 6:137,048,812...137,086,194
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr 3:38,036,565...38,041,014
Ensembl chr 3:38,319,024...38,323,572
JBrowse link
G MYLK myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :
Asthma, Aspirin-Induced; DNA:polymorphism: :
RGD PMID:16924569 PMID:20602614 RGD:5131600 RGD:5131606 NCBI chr 8:17,606,445...17,623,397
Ensembl chr 8:14,575,455...14,576,327
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NGF nerve growth factor severity ISO protein:increased expression:lung, serum
protein:increased expression:blood, eosinophil
RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:insertion:cds:
DNA:SNP: :rs2075817 (human)
RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G NOS1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:exon
DNA:repeats:intron
DNA:repeats: :
RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
G NOS2 nitric oxide synthase 2 disease_progression
no_association
severity
ISO protein:increased expression:lung, bronchoalveolar lavage fluid
DNA:repeat:promoter
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeats:promoter, introns (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
mRNA:increased expression:monocyte
DNA:SNP:exon:p.S608L (human)
RGD
CTD
PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233
JBrowse link
G NPSR1 neuropeptide S receptor 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 OMIM
ClinVar
PMID:15073379 NCBI chr 7:35,274,102...35,494,389
Ensembl chr 7:35,663,335...35,883,988
JBrowse link
G NPY neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
DNA:SNP:exon:c.609C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chr16:50,090,696...50,106,495
Ensembl chr16:69,470,288...69,489,731
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 severity
treatment
susceptibility
ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron
RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G NTF3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO protein:increased activation:lung, blood, mononuclear cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr2B:129,111,509...129,121,127 JBrowse link
G PDE4B phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291
JBrowse link
G PDE4D phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PGF placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
JBrowse link
G PLA2G7 phospholipase A2 group VII susceptibility ISO ClinVar Annotator: match by term: Asthma and atopy, susceptibility to OMIM
ClinVar
PMID:10733466 PMID:15115767 NCBI chr 6:46,264,262...46,318,487
Ensembl chr 6:47,558,861...47,590,212
JBrowse link
G PLAU plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18519237 PMID:21912604 RGD:4892037 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chr10:67,071,141...67,078,057
Ensembl chr10:69,597,574...69,603,070
JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein no_association
severity
disease_progression
ISO mRNA:increased expression:eosinophil:
associated with viral infection;mRNA:increased expression:sputum:
associated with cough;protein:increased expression:sputum:
RGD PMID:11067904 PMID:16982448 PMID:22022864 PMID:24450586 RGD:13506941 RGD:13506942 RGD:13506943 RGD:13506944 NCBI chr11:52,628,289...52,631,634
Ensembl chr 3:160,118,111...160,122,002
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135
JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr21:33,100,101...33,130,060
Ensembl chr21:46,233,951...46,263,570
JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr11:20,412,419...20,538,295
Ensembl chr11:20,324,196...20,449,681
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr2B:32,846,899...32,859,060
Ensembl chr2B:128,083,794...128,094,625
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G PTGDR prostaglandin D2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr14:32,863,852...32,873,492
Ensembl chr14:51,149,155...51,158,161
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chr11:56,114,166...56,153,820
Ensembl chr11:59,556,460...59,557,647
JBrowse link
G PTGER3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
DNA:SNP: :rs689465 (human)
mRNA, protein:increased expression:lung:
RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 1:134,283,998...134,329,531
Ensembl chr 1:138,081,611...138,127,115
JBrowse link
G RAD50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 5:127,972,630...128,059,911
Ensembl chr 5:134,134,495...134,222,261
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr21:21,159,586...21,423,946
Ensembl chr21:34,530,956...34,788,544
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
ClinVar
PMID:9550363 PMID:21255142 RGD:5144226 NCBI chr11:57,774,560...57,780,334
Ensembl chr11:61,133,649...61,137,873
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)
OMIM
ClinVar
RGD
PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chr 5:143,319,941...143,323,625
Ensembl chr 5:149,329,201...149,333,003
JBrowse link
G SELL selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chr 1:145,173,700...145,194,927
Ensembl chr 1:148,895,373...148,916,393
JBrowse link
G SERPINA1 serpin family A member 1 ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419
JBrowse link
G SERPINE1 serpin family E member 1 severity
susceptibility
no_association
ISO protein:increased expression:plasma
DNA:polymorphism:promoter:rs1799768 (human)
protein:increased activity, increased expression:plasma, lung
RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G SFTPA1 surfactant protein A1 ISO protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung
RGD PMID:15816355 PMID:16629790 PMID:18802356 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143516 NCBI chr10:76,571,312...76,575,820 JBrowse link
G SFTPB surfactant protein B ISO protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chr2A:85,708,485...85,718,120
Ensembl chr2A:87,257,244...87,268,332
JBrowse link
G SFTPC surfactant protein C susceptibility ISO mRNA, protein:decreased expression:lung
protein:increased expression:lung
DNA:polymorphism: :p.A53T (human)
RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chr 8:21,402,060...21,409,438
Ensembl chr 8:18,345,940...18,348,764
JBrowse link
G SFTPD surfactant protein D ISO associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chr10:76,275,147...76,318,952
Ensembl chr10:78,965,252...78,974,181
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr2B:105,640,613...105,655,524
Ensembl chr2B:224,238,284...224,252,941
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr10:44,630,006...44,632,419 JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr 6:158,004,545...158,046,428
Ensembl chr 6:163,014,663...163,054,681
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860
JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G SPRR2B small proline rich protein 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:128,412,256...128,413,641
Ensembl chr 1:132,040,869...132,041,087
JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28807506 NCBI chr2B:78,331,402...78,549,231
Ensembl chr2B:196,247,881...196,366,011
JBrowse link
G TAC1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA,protein:increased expression:lung
mRNA:increased expression:lung
RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G TACR2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr 6:32,414,665...32,423,488
Ensembl chr 6:33,530,171...33,538,978
JBrowse link
G TBX21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15806396 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G TBXA2R thromboxane A2 receptor severity
susceptibility
ISO DNA:polymorphism:cds:924T>C(human) RGD PMID:12000493 PMID:15805995 RGD:11059534 RGD:11059535 NCBI chr19:2,621,606...2,632,800
Ensembl chr19:3,570,290...3,581,924
JBrowse link
G TGFB1 transforming growth factor beta 1 onset
no_association
ISO protein:increased expression:serum
DNA:polymorphism: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:915G>C (human)
DNA:SNP: :-509C>T (human)
mRNA:increased expression:lung
DNA:polymorphisms: :multiple (human)
DNA:SNPs:promoter, exon:multiple (human)
RGD
CTD
PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G THBD thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964
JBrowse link
G TLR1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:33,119,485...33,133,541
Ensembl chr 4:38,979,006...38,981,366
JBrowse link
G TLR10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:33,100,588...33,111,750
Ensembl chr 4:38,955,660...38,958,095
JBrowse link
G TLR2 toll like receptor 2 susceptibility
severity
ISO DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs3804100 (human)
DNA:SNP: :rs4696480 (human)
RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G TLR3 toll like receptor 3 no_association ISO DNA:snp:cds:p.L412F (human)
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728
JBrowse link
G TLR4 toll like receptor 4 susceptibility
no_association
severity
ISO DNA:Polymorphism:cds:p.D299G (human)
DNA:SNPs::
DNA:SNPs: :rs10983755, rs1927914 (human)
protein:decreased expression:leukocytes, mononuclear
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TLR6 toll like receptor 6 susceptibility ISO DNA:SNP: :p.S249P (human)
DNA:SNP (human)
RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chr 4:33,153,151...33,174,053
Ensembl chr 4:39,009,103...39,011,490
JBrowse link
G TNF tumor necrosis factor susceptibility
no_association
ISO ClinVar Annotator: match by term: ASTHMA, BRONCHIAL
DNA:polymorphism:promoter:
OMIM
ClinVar
RGD
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143254 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr12:6,457,617...6,470,969
Ensembl chr12:6,374,257...6,387,613
JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr 5:146,457,347...146,514,515
Ensembl chr 5:152,459,868...152,510,540
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627
JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 5:106,440,136...106,446,849
Ensembl chr 5:112,242,490...112,250,130
JBrowse link
G UCN urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688
JBrowse link
G VDR vitamin D receptor no_association ISO DNA:SNPs: :multiple (human)
DNA:SNP: :rs7975232 (human)
DNA:SNPs (human)
DNA:SNP (human)
RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chr 6:150,564,545...150,573,582
Ensembl chr 6:155,254,652...155,263,730
JBrowse link
G WDR36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 5:106,461,658...106,499,837
Ensembl chr 5:112,264,403...112,302,549
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr 7:68,230,804...68,251,369
Ensembl chr 7:82,221,846...82,242,874
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:67,412,410...67,469,366
Ensembl chr  X:77,524,455...77,525,468
JBrowse link
G EPX eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr17:52,269,114...52,281,471
Ensembl chr17:57,124,924...57,136,992
JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr14:4,191,888...4,195,043
Ensembl chr14:22,286,347...22,289,498
JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G LOC100995577 HLA class II histocompatibility antigen, DP alpha 1 chain susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:32,637,826...32,646,501
Ensembl chr 6:33,752,638...33,761,417
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 RGD:126928124 NCBI chr 6:40,861,283...40,874,446
Ensembl chr 6:42,163,337...42,183,091
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr19:50,927,916...50,948,924
Ensembl chr19:59,774,925...59,793,079
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20022477 PMID:20485159 RGD:4145619 NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:67,412,410...67,469,366
Ensembl chr  X:77,524,455...77,525,468
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chr13:29,796,598...29,853,676
Ensembl chr13:48,551,757...48,552,797
JBrowse link
G FANCC FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr 9:66,201,581...66,418,229
Ensembl chr 9:94,329,971...94,477,198
JBrowse link
G IL4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G LTC4S leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr 5:174,946,346...174,950,805 JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr11:55,318,843...55,326,779
Ensembl chr11:58,764,911...58,772,567
JBrowse link
G POSTN periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr11:56,114,166...56,153,820
Ensembl chr11:59,556,460...59,557,647
JBrowse link
G PTGER2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chr14:32,910,755...32,926,138
Ensembl chr14:51,195,381...51,209,686
JBrowse link
G PTGIR prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr19:43,613,065...43,617,700
Ensembl chr19:52,141,822...52,146,473
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mast cell
CTD
RGD
PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chr 6:32,394,586...32,408,297
Ensembl chr 6:33,507,332...33,523,750
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chr19:2,621,606...2,632,800
Ensembl chr19:3,570,290...3,581,924
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
JBrowse link
G PTGER2 prostaglandin E receptor 2 ISO OMIM NCBI chr14:32,910,755...32,926,138
Ensembl chr14:51,195,381...51,209,686
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr14:16,155,331...16,158,588 JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 severity ISO protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chr 7:68,230,804...68,251,369
Ensembl chr 7:82,221,846...82,242,874
JBrowse link
G EPX eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chr17:52,269,114...52,281,471
Ensembl chr17:57,124,924...57,136,992
JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr2B:110,100,210...110,181,277
Ensembl chr2B:228,706,142...228,759,882
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G CDH17 cadherin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G LOC100967723 HLA class II histocompatibility antigen, DO alpha chain treatment ISO DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:32,573,975...32,579,398
Ensembl chr 6:33,689,171...33,694,576
JBrowse link
G LOC100976978 E3 ubiquitin-protein ligase HERC2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr15:1,590,558...1,800,023
Ensembl chr15:25,536,483...25,746,074
JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain susceptibility ISO DNA:SNP: :rs1811197(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain susceptibility ISO DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
JBrowse link
G PRKCA protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903
JBrowse link
G PRKD1 protein kinase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr14:10,353,284...10,707,841
Ensembl chr14:28,496,282...28,650,030
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G TENM3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 4:173,644,674...174,993,218
Ensembl chr 4:186,738,624...187,214,394
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII ISO ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency OMIM
ClinVar
PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chr 6:46,264,262...46,318,487
Ensembl chr 6:47,558,861...47,590,212
JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
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G IL1B interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
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G IL5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
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G MPO myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14616
    disease of anatomical entity 14326
      respiratory system disease 3071
        respiratory allergy 367
          asthma 334
            Asthma and Nasal Polyps 2
            Asthma, Short Stature, and Elevated IgA 0
            Eosinophilic Asthma 2
            Platelet-Activating Factor Acetylhydrolase Deficiency 1
            acute asthma + 5
            atopic dermatitis 3 0
            chronic asthma + 46
Path 2
Term Annotations click to browse term
  disease 14616
    disease of anatomical entity 14326
      Immune & Inflammatory Diseases 4547
        immune system disease 4014
          allergic disease 558
            Immediate Hypersensitivity 426
              respiratory allergy 367
                asthma 334
                  Asthma and Nasal Polyps 2
                  Asthma, Short Stature, and Elevated IgA 0
                  Eosinophilic Asthma 2
                  Platelet-Activating Factor Acetylhydrolase Deficiency 1
                  acute asthma + 5
                  atopic dermatitis 3 0
                  chronic asthma + 46
paths to the root