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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hematologic cancer
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Accession:DOID:2531 term browser browse the term
Definition:An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes. (DO)
Synonyms:exact_synonym: blood cancer;   hematologic malignancies;   hematologic malignancy;   hematological malignancies;   hematological malignancy;   hematological tumors;   hematopoietic and lymphoid system tumor;   hematopoietic cancer;   hematopoietic tumors;   malignant hematopoietic neoplasm
 xref: NCI:C27134
For additional species annotation, visit the Alliance of Genome Resources.


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hematologic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Hematological malignancies ClinVar PMID:7479840 PMID:7513208 PMID:7691885 PMID:8589724 PMID:9657776 More... NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ameliorates ISO DNA:missense mutation:CDS:p.H27R (human) RGD PMID:21984221 RGD:10449413 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G TP53 tumor protein p53 ISO DNA:missense mutation::p.R337H (human) RGD PMID:28387921 RGD:14995484 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
acute biphenotypic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOT1L DOT1 like histone lysine methyltransferase treatment ISO RGD PMID:23801631 RGD:9588291 NCBI chr20:56,805,030...56,868,771
Ensembl chr20:56,803,242...56,852,539 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO OMIM NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G RNF20 ring finger protein 20 disease_progression ISO RGD PMID:23412334 RGD:9831405 NCBI chr11:58,239,245...58,266,637
Ensembl chr11:58,239,313...58,265,866 		JBrowse link
Acute Erythroleukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX41 DEAD-box helicase 41 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 4:35,854,382...35,859,853
Ensembl chr 4:35,854,597...35,859,852 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812 		JBrowse link
G HOXB9 homeobox B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 9:24,884,101...24,889,904
Ensembl chr 9:24,872,950...24,889,376 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
G NUP98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
acute leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO ClinVar Annotator: match by term: Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified ClinVar PMID:7585650 PMID:9195225 PMID:15982307 PMID:22234153 PMID:23221806 More... NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:snps, haplotype:multiple (human)		 CTD
RGD		 PMID:22674224 RGD:8657089 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 treatment ISO DNA:SNPs: :rs717620(human)
DNA:SNP:5'UTR:rs717620(human)		 RGD PMID:24404132 PMID:25007187 RGD:11080959 RGD:11080979 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 disease_progression ISO mRNA:increased expression:mononuclear cell: RGD PMID:12100141 PMID:15521915 RGD:11081076 RGD:11081143 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11984797 PMID:21898527 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO RGD PMID:17065136 RGD:11100012 NCBI chr 9:49,746,749...49,758,317
Ensembl chr 9:49,748,693...49,758,479 		JBrowse link
G AICDA activation induced cytidine deaminase treatment ISO RGD PMID:19759560 RGD:11039451 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789 		JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19684603 PMID:19684604 NCBI chr 4:13,926,759...14,105,069
Ensembl chr 4:13,927,217...14,101,364 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 Ensembl chr17:59,941,353...60,010,867
Ensembl chr17:59,941,353...60,010,867 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464 		JBrowse link
G BCL2 BCL2 apoptosis regulator severity ISO mRNA:increased expression:bone marrow (human) RGD PMID:25982455 RGD:11076595 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO mRNA:increased expression:blood, mononuclear cell (human) RGD PMID:12469194 PMID:19020783 RGD:11353852 RGD:11353866 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr26:27,856,280...27,980,923
Ensembl chr26:27,856,082...27,978,318 		JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: therapeutic CTD PMID:22010212 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G CAST calpastatin ISO protein:increased expresssion:B cell RGD PMID:11264179 RGD:5509822 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959 		JBrowse link
G CCND1 cyclin D1 ISO mRNA:increased expression:bone marrow (human) RGD PMID:22391157 RGD:11352824 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:9292526 RGD:11352271 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CD79B CD79b molecule ISO protein:decreased expression:bone marrow, mononuclear cell (human) RGD PMID:21487112 RGD:11250414 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843 		JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:peripheral blood, bone marrow, mononuclear cell (human) RGD PMID:24283754 RGD:11354967 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24736461 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression
susceptibility
no_association		 ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:		 RGD
CTD		 PMID:9204978 PMID:10090949 PMID:20453839 PMID:25675863 PMID:26104880 RGD:11057958 RGD:11251764 RGD:11252081 RGD:11252082 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:19684604 NCBI chr 8:3,423,046...3,425,595
Ensembl chr 8:3,423,040...3,425,217 		JBrowse link
G CFB complement factor B ISO DNA:missense mutation:p.R32Q b(human) RGD PMID:6958349 RGD:11041155 NCBI chr12:1,400,143...1,406,267 JBrowse link
G CREBBP CREB binding protein disease_progression ISO DNA:mutations:multiple RGD PMID:25917266 RGD:11060149 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G CRLF2 cytokine receptor like factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:780,924...801,961
Ensembl chr  X:780,711...802,836 		JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:9250830 RGD:11039038 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 severity ISO RGD PMID:8562939 RGD:734840 NCBI chr30:38,465,486...38,498,365
Ensembl chr30:38,465,241...38,497,971 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO mRNA:increased expression:peripheral blood mononuclear cell: RGD PMID:19222940 RGD:11040545 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association
susceptibility		 ISO DNA:polymorphism:3'UTR:3801T>C(human)
DNA:polymorphism:cds:2452C>A(p.T461N)(human)
DNA:polymorphism:3"UTR:rs4646903(human)		 RGD PMID:16676594 PMID:22964275 PMID:23725389 RGD:11352714 RGD:11352725 RGD:11352728 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 susceptibility ISO DNA:polymorphisms: :
DNA:SNP,deletion:splice junction,exon:1934G>A(human)		 RGD PMID:11037802 PMID:19593802 RGD:11252111 RGD:11352820 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11774269 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G DHFR dihydrofolate reductase disease_progression ISO DNA:polymorphisms, haplotype:promoter:
DNA:polymorphisms: :-317A>G, 829C>T (human)		 RGD PMID:9226157 PMID:12972803 PMID:19861437 PMID:22969948 RGD:11039542 RGD:11039543 RGD:11039544 RGD:11039545 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G DNMT3A DNA methyltransferase 3 alpha treatment ISO DNA:mutations:exon, intron:p.R882(human) RGD PMID:25242092 RGD:11041125 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNTT DNA nucleotidylexotransferase ISO protein:increased activity:peripheral blood,bone marrow: RGD PMID:7020399 RGD:8694149 NCBI chr28:9,729,812...9,759,019
Ensembl chr28:9,729,814...9,759,008 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase disease_progression
no_association		 ISO DNA:splice-site mutation:intron:IVS14+1G>A (human)
DNA:SNPs: :2194G>A, 1156G>T (human)
DNA:SNP: :85T>C (human)		 RGD PMID:26846104 RGD:11098453 NCBI chr 6:51,789,786...52,564,802
Ensembl chr 6:51,814,573...52,580,923 		JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32889036 NCBI chr 9:48,031,593...48,110,954
Ensembl chr 9:48,032,709...48,175,828 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32889036 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584 		JBrowse link
G ENG endoglin disease_progression ISO RGD PMID:17572488 RGD:11041565 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility
no_association		 ISO DNA:polymorphisms:exon
DNA:SNPs:exon:rs1051740, rs2234922 (human)
DNA:missense mutation, haplotype:exon:p.H139R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation, haplotype:exon:p.Y113H (human)		 RGD
CTD		 PMID:19593802 PMID:21983886 PMID:22200898 PMID:22930568 RGD:11252110 RGD:11252111 RGD:11252113 RGD:11252114 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:SNPs, haplotypes: :p.R194W, p.R280H, p.R399Q (human)
DNA:SNPs: :8092C>A, 19007G>A (human)		 RGD PMID:16435384 PMID:16723154 RGD:11252160 RGD:11340204 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association ISO DNA:missense mutations: :p.D312N, p.K751Q (human)
DNA:haplotype		 RGD PMID:19101034 PMID:21987080 RGD:11252192 RGD:11340201 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
G ERG ETS transcription factor ERG ISO CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr31:33,456,902...33,562,704
Ensembl chr31:33,497,209...33,515,272 		JBrowse link
G ETV6 ETS variant transcription factor 6 ISO ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar NCBI chr27:34,351,206...34,587,060
Ensembl chr27:34,343,390...34,587,060 		JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:8429686 RGD:11340211 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G FAS Fas cell surface death receptor disease_progression ISO protein:increased expression:CD34+ bone marrow cell RGD PMID:9711907 PMID:10500800 RGD:11049148 RGD:11049157 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:serum (human) RGD PMID:25317080 RGD:11040558 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 susceptibility ISO ClinVar Annotator: match by term: Acute lymphoid leukemia OMIM
ClinVar		 PMID:11290608 PMID:11442493 PMID:14604974 PMID:14670924 PMID:15256420 More... NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FPGS folylpolyglutamate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25013492 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028 		JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35115686 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:blood: RGD PMID:19360458 RGD:11040460 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812 		JBrowse link
G GNB1 G protein subunit beta 1 susceptibility ISO ClinVar Annotator: match by term: Acute lymphoblastic leukemia | ClinVar Annotator: match by term: Lymphoblastic leukemia OMIM
ClinVar		 PMID:25485910 PMID:25741868 PMID:27108799 PMID:28492532 PMID:32134617 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:6589021 RGD:11051848 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO RGD PMID:17317918 PMID:24698347 RGD:11352774 RGD:11352812 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24191316 RGD:11059506 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 disease_progression
susceptibility
no_association		 ISO DNA:haplotype:cds:
DNA:transition mutation:exon:
DNA:polymorphism: :1578 a>G(human)		 RGD PMID:10666194 PMID:15738600 PMID:23979883 RGD:10450829 RGD:10755321 RGD:10755417 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G H1-2 H1.2 linker histone, cluster member susceptibility ISO DNA:SNP, haplotype:enhancer: (rs807212) (human) RGD PMID:19806355 RGD:10755490 NCBI chr35:24,009,304...24,011,602 JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17344919 NCBI chr24:21,473,424...21,513,673
Ensembl chr24:21,473,305...21,513,564 		JBrowse link
G HDAC1 histone deacetylase 1 disease_progression ISO mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186 		JBrowse link
G HDAC2 histone deacetylase 2 disease_progression ISO mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578 		JBrowse link
G HDAC4 histone deacetylase 4 treatment ISO RGD PMID:23948281 RGD:9681454 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G HFE homeostatic iron regulator no_association ISO DNA:missense mutation:cds:p.C282Y (human)
DNA:missense mutation: :p.H63D (human)
DNA:missense mutation:cds:p.H63D (human)		 RGD PMID:10627122 PMID:17107905 RGD:10755557 RGD:10755558 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HK1 hexokinase 1 ISO protein:decreased activity:platelet RGD PMID:21921332 RGD:11353881 NCBI chr 4:20,396,761...20,516,889
Ensembl chr 4:20,421,526...20,518,211 		JBrowse link
G HLF HLF transcription factor, PAR bZIP family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr 9:30,321,090...30,380,480
Ensembl chr 9:30,327,495...30,377,175 		JBrowse link
G HOXD4 homeobox D4 ISO ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to ClinVar PMID:15776434
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219 		JBrowse link
G IFNG interferon gamma susceptibility ISO DNA:SNP: :rs2069727(human) RGD PMID:21067287 RGD:10755691 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphocytic, susceptibility to, 2 ClinVar NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768 		JBrowse link
G IKZF2 IKAROS family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr37:20,508,647...20,662,549
Ensembl chr37:20,516,239...20,661,298 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385 		JBrowse link
G IL10 interleukin 10 treatment ISO protein:decreased expression:blood RGD PMID:15860861 PMID:21653647 RGD:11049158 RGD:11049169 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IRF4 interferon regulatory factor 4 ISO DNA:SNP:intron:rs12203592 (human) RGD PMID:19897031 RGD:11526162 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G ITPA inosine triphosphatase treatment
no_association		 ISO DNA:SNPs:exon:94C>A, 138G>A (human)
DNA:SNP:intron		 RGD PMID:22009189 RGD:10766474 NCBI chr24:18,070,980...18,081,815
Ensembl chr24:18,064,983...18,082,163 		JBrowse link
G KDM2B lysine demethylase 2B ISO mRNA:increased expression:bone marrow (human) RGD PMID:21310926 RGD:9588255 NCBI chr26:7,625,857...7,746,049
Ensembl chr26:7,598,931...7,745,113 		JBrowse link
G KDM3B lysine demethylase 3B ISO protein:increased expression:bone marrow, mononuclear cell (human) RGD PMID:22615488 RGD:9586728 NCBI chr11:25,954,352...26,024,919
Ensembl chr11:25,943,864...26,023,866 		JBrowse link
G KDM6A lysine demethylase 6A severity ISO DNA:mutations:cds:multiple (human) RGD PMID:22377896 RGD:9684944 NCBI chr  X:38,745,854...38,964,029
Ensembl chr  X:38,745,854...38,959,842 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24736461 PMID:25730765 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:17910045 PMID:25917266 RGD:11060148 RGD:11060149 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LOC100683783 double homeobox protein 4C-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr17:64,277,421...64,282,701 JBrowse link
G LOC486411 immunoglobulin iota chain-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr26:28,833,763...28,834,870
Ensembl chr26:28,833,136...28,834,679 		JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like ISO protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:16353080 RGD:11352810 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:polymorphisms:cds:p.E148Q,M680I(human) RGD PMID:22942567 RGD:11531121 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase treatment
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:677C>T (human)
DNA:missense mutation:cds:677C>T (p.A222V) (rs1801133) (human)		 CTD
RGD		 PMID:16706930 PMID:19923983 PMID:21644011 RGD:10449398 RGD:10449407 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase no_association
disease_progression
susceptibility		 ISO DNA:polymorphism: :2756A>G(human)
DNA:SNP::rs10925235(human)
DNA:polymorphism: :66A>G(human)		 RGD PMID:15159311 PMID:21618417 PMID:22453148 PMID:26605150 RGD:11531136 RGD:11531137 RGD:11531140 RGD:11531141 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:SNP: :rs3776455(human)
CTD Direct Evidence: marker/mechanism
DNA:haplotype:cds:		 RGD
CTD		 PMID:17136115 PMID:23940529 RGD:11531133 RGD:11531135 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression ISO RGD PMID:25784651 RGD:11532748 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G NBN nibrin susceptibility ISO ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to OMIM
ClinVar		 PMID:9590180 PMID:11325820 PMID:14559852 PMID:15338273 PMID:16415040 More... NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563 		JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
disease_progression		 ISO DNA:SNP: :rs3918186(human)
DNA:polymorphism, haplotype:cds,intron:P.E298D,-786T>C(human)		 RGD PMID:20510681 PMID:23922896 RGD:11533639 RGD:11533646 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO DNA:missense mutations: :p.R139W (465C>T), p.P187S (609C>T) (human)
DNA:mutation: :609C>T (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11774269 PMID:17332311 PMID:18444911 RGD:10769347 RGD:10769359 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO DNA:missense mutation:cds: RGD PMID:25204082 RGD:11535045 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24076604 NCBI chr 3:62,164,888...62,228,006
Ensembl chr 3:62,167,939...62,228,035 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II ISO CTD Direct Evidence: marker/mechanism CTD PMID:23377183 NCBI chr28:15,525,581...15,621,287
Ensembl chr28:15,526,790...15,621,235 		JBrowse link
G NUP214 nucleoporin 214 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 9:52,840,300...52,943,785
Ensembl chr 9:52,841,096...52,947,770 		JBrowse link
G P2RY8 P2Y receptor family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:1,060,204...1,097,471 JBrowse link
G PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr29:28,207,445...28,340,812
Ensembl chr29:28,211,031...28,263,322 		JBrowse link
G PAX5 paired box 5 susceptibility ISO ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3 OMIM
ClinVar		 PMID:24013638 PMID:24728327 PMID:25741868 NCBI chr11:53,194,905...53,390,204
Ensembl chr11:53,201,344...53,390,974 		JBrowse link
G PON1 paraoxonase 1 susceptibility ISO DNA:missense mutations:cds:p.L55M (rs854560), p.Q192R (rs662) (human) RGD PMID:22976839 RGD:11552580 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:blood (human) RGD PMID:27275197 RGD:11535025 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PRDM14 PR/SET domain 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19043588 NCBI chr29:19,203,798...19,220,149
Ensembl chr29:19,203,807...19,220,518 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726 		JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:decreased expression:bone marrow, blood, mononuclear cell (human) RGD PMID:23915977 RGD:10768836 NCBI chr38:515,808...521,536
Ensembl chr38:515,860...521,535 		JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr15:13,446,752...13,462,038
Ensembl chr15:13,449,481...13,462,047 		JBrowse link
G TAL2 TAL bHLH transcription factor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr11:61,425,927...61,484,525
Ensembl chr11:61,456,727...61,482,348 		JBrowse link
G TCF3 transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr20:57,255,091...57,284,223
Ensembl chr20:57,254,384...57,283,981 		JBrowse link
G TCN2 transcobalamin 2 ISO protein:altered activity:plasma: RGD PMID:8754152 RGD:11059889 NCBI chr26:23,693,664...23,710,342
Ensembl chr26:23,693,773...23,709,832 		JBrowse link
G TERT telomerase reverse transcriptase ISO DNA:SNPs:promoter, introns:g.1296486C>T, g.12866516A>C, g.1279790G>A (rs2735940, rs2736100, rs10069690) (human) RGD PMID:15621763 PMID:23066086 RGD:11038654 RGD:11038667 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 ISO mRNA:increased expression:bone marrow, mononuclear cells (human) RGD PMID:12730115 RGD:2317244 NCBI chr22:49,515,350...49,578,519
Ensembl chr22:49,515,382...49,577,905 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TPMT thiopurine S-methyltransferase treatment
no_association		 ISO DNA:SNPs:multiple
DNA:SNPs:introns:12356C>T, 16638C>T, 26354G>T (rs4449636, rs2518463, rs2842949) (human)
DNA:SNPs: :multiple
DNA:SNPs:exon:374C>T, 719A>G (rs2842934, rs1142345) (human)		 RGD PMID:17164697 PMID:22009189 PMID:24499706 RGD:10766474 RGD:11038720 RGD:11038723 NCBI chr35:16,928,991...16,953,891
Ensembl chr35:16,929,240...16,953,229 		JBrowse link
G TYMS thymidylate synthetase treatment ISO DNA:repeats: : rs347430033(human) RGD PMID:25007187 RGD:11080979 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association		 ISO DNA:missense mutation: :p.R194W (human)
DNA:missense mutation, haplotype: :p.R399Q (human)
DNA:missense mutation: :p.R399Q (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19101034 PMID:21983886 RGD:11252110 RGD:11252192 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816 		JBrowse link
Acute Lymphoblastic Leukemia, with Lymphomatous Features term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10988075 PMID:11423618 PMID:11853795 PMID:11861307 PMID:11964322 More... NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G CRLF2 cytokine receptor like factor 2 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:19907440 PMID:19965641 PMID:20018760 PMID:22368272 NCBI chr  X:780,924...801,961
Ensembl chr  X:780,711...802,836 		JBrowse link
G CYP2B6 cytochrome P450 2B11 susceptibility ISO DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G IL7R interleukin 7 receptor ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:22897847 PMID:22955920 NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300 		JBrowse link
G INSL6 insulin like 6 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 1:93,457,854...93,474,777
Ensembl chr 1:93,459,945...93,474,793 		JBrowse link
G JAK1 Janus kinase 1 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 More... NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK2 Janus kinase 2 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: LYMPHOMATOUS ALL ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:20132407 PMID:20372971 More... NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
acute megakaryocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 ISO RGD PMID:21640380 RGD:11081147 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16166298 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO associated with Down Syndrome;DNA:mutations:multiple (human) RGD PMID:24056718 RGD:10450890 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G GATA1 GATA binding protein 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:15070711 PMID:16783379 PMID:22706301 PMID:23704091 PMID:24453067 More... NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303 		JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812 		JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia | ClinVar Annotator: match by term: Acute megakaryocytic leukemia ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:18397343 PMID:20132407 More... NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G LOC102152446 coronin-7 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 6:36,980,302...37,038,210 JBrowse link
G MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr12:6,655,586...6,716,619
Ensembl chr12:6,659,910...6,686,760 		JBrowse link
G MRTFA myocardin related transcription factor A ISO RGD PMID:11431691 RGD:1599948 NCBI chr10:24,561,161...24,759,586
Ensembl chr10:24,561,161...24,759,081 		JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr MT:13,582...14,109
Ensembl chr MT:13,582...14,109 		JBrowse link
G PCF11 PCF11 cleavage and polyadenylation factor subunit ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr21:16,006,022...16,028,369
Ensembl chr21:16,006,749...16,028,021 		JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO associated with Down Syndrome;mRNA:increased expression:mononuclear cell (human) RGD PMID:15180862 RGD:11535064 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Acute megakaryocytic leukemia ClinVar PMID:10848731 PMID:17941496 PMID:20600018 PMID:21194675 PMID:21343951 More... NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G RASAL3 RAS protein activator like 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr20:46,733,072...46,743,657
Ensembl chr20:46,732,952...46,743,924 		JBrowse link
G RUNX1 RUNX family transcription factor 1 onset ISO RGD PMID:15856017 RGD:11251701 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G SLC9A2 solute carrier family 9 member A2 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr10:40,334,417...40,394,438
Ensembl chr10:40,338,284...40,394,470 		JBrowse link
G SNCB synuclein beta ISO RGD PMID:21264917 RGD:6478703 NCBI chr 4:36,710,236...36,719,455
Ensembl chr 4:36,616,039...36,764,501 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:11370630 PMID:20522432 PMID:28492532 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
acute monocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21399634 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor ISO RGD PMID:7662954 RGD:1598771 NCBI chr 2:11,349,864...11,607,194
Ensembl chr 2:11,349,856...11,596,398 		JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382 		JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:25117502 PMID:25741868 PMID:25980754 PMID:26467025 PMID:28492532 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118 		JBrowse link
acute myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC3 ATP binding cassette subfamily C member 3 disease_progression ISO RGD PMID:26512967 RGD:11081145 NCBI chr 9:26,551,953...26,596,330
Ensembl chr 9:26,551,268...26,595,646 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 treatment
disease_progression		 ISO RGD PMID:12145683 PMID:26512967 RGD:11081145 RGD:11099971 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO DNA:translocation: : RGD PMID:12161353 RGD:10450603 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO DNA:translocation: :t(5;12)(q31;p13) (human) RGD PMID:10502316 RGD:1599805 NCBI chr11:20,226,877...20,284,919
Ensembl chr11:20,227,268...20,285,631 		JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 2:65,003,891...65,034,812
Ensembl chr 2:65,006,038...65,034,777 		JBrowse link
G AGRN agrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:56,239,621...56,273,679
Ensembl chr 5:56,239,701...56,272,745 		JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 ISO mRNA:increased expression:blood (human) RGD PMID:26046517 RGD:11067888 NCBI chr 9:48,475,777...48,486,715
Ensembl chr 9:48,471,584...48,609,303 		JBrowse link
G ANXA2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281 		JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:68,418,678...68,466,181
Ensembl chr10:68,431,056...68,466,174 		JBrowse link
G ANXA5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378 		JBrowse link
G ANXA6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:58,091,186...58,140,102
Ensembl chr 4:58,091,251...58,139,372 		JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: therapeutic CTD PMID:16968895 NCBI chr30:23,223,413...23,271,893
Ensembl chr30:23,225,331...23,269,076 		JBrowse link
G ASMTL acetylserotonin O-methyltransferase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr  X:1,102,094...1,118,791
Ensembl chr  X:1,100,747...1,118,791 		JBrowse link
G ASXL1 ASXL transcriptional regulator 1 disease_progression ISO DNA:mutations:exon: RGD PMID:20693432 RGD:11038706 NCBI chr24:21,725,126...21,804,745
Ensembl chr24:21,661,059...21,802,815 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691 		JBrowse link
G ATG2B autophagy related 2B ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,039,960...65,110,811
Ensembl chr 8:65,044,194...65,110,796 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:29,464,132...29,487,124
Ensembl chr 7:29,464,132...29,487,947 		JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr13:4,602,688...4,684,138
Ensembl chr13:4,603,020...4,682,189 		JBrowse link
G BACH2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr12:49,101,621...49,375,415
Ensembl chr12:49,106,523...49,460,286 		JBrowse link
G BCL2 BCL2 apoptosis regulator severity
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
ratio with Flt3, Kit;mRNA:decreased expression:mononuclear cell (human)
DNA:snp:exon:c.+21A>G (rs1801018) (human)
DNA:snp:promoter:g.-938C>A (human)		 CTD
RGD		 PMID:19520430 PMID:23906301 PMID:25216797 PMID:25957891 RGD:11526107 RGD:11526109 RGD:11526111 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BCL2L1 BCL2 like 1 severity ISO mRNA:increased expression:peripheral blood, bone marrow, blast cell (human) RGD PMID:11410409 RGD:11353851 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:16105758 RGD:1580059 NCBI chr 2:10,818,232...10,828,473
Ensembl chr 2:10,818,232...10,833,613 		JBrowse link
G BRD4 bromodomain containing 4 ISO RGD PMID:21814200 RGD:9586350 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608 		JBrowse link
G BRD7 bromodomain containing 7 susceptibility ISO DNA:haplotype:cds:737A>G,495C>T(human)
mRNA:increased expression:bone marrow:		 RGD PMID:18772500 RGD:9586443 NCBI chr 2:64,966,636...65,002,800
Ensembl chr 2:64,966,392...65,002,799 		JBrowse link
G BTG1 BTG anti-proliferation factor 1 disease_progression ISO RGD PMID:15449376 RGD:1549463 NCBI chr15:32,646,520...32,648,222
Ensembl chr15:32,647,472...32,647,762 		JBrowse link
G C8H14orf132 chromosome 8 C14orf132 homolog ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:64,813,713...64,861,449
Ensembl chr 8:64,813,303...64,855,348 		JBrowse link
G CALR calreticulin ISO mRNA:increased expression:peripheral blood (human) RGD PMID:26640226 RGD:11076986 NCBI chr20:49,251,390...49,255,291
Ensembl chr20:49,251,777...49,255,245 		JBrowse link
G CAPG capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr17:39,619,429...39,640,944
Ensembl chr17:39,619,248...39,640,942 		JBrowse link
G CAPN2 calpain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:40,333,379...40,367,158
Ensembl chr 7:40,334,012...40,377,037 		JBrowse link
G CASP7 caspase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr28:24,599,866...24,630,018
Ensembl chr28:24,599,493...24,628,668 		JBrowse link
G CBFB core-binding factor subunit beta ISO ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:25741868 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168 		JBrowse link
G CBL Cbl proto-oncogene disease_progression ISO associated with Myelodysplastic Syndromes;DNA:mutations:exons: RGD PMID:22131879 RGD:11038796 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO protein:increased expression:plasma (human) RGD PMID:17822317 PMID:25382729 RGD:11528532 RGD:11528537 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCNA1 cyclin A1 ISO protein:increased expression:leukocyte (human) RGD PMID:10068680 RGD:2316304 NCBI chr25:4,189,457...4,198,170
Ensembl chr25:4,189,457...4,198,373 		JBrowse link
G CCND1 cyclin D1 treatment ISO human tumor in a mouse model
mRNA:increased expression:bone marrow (human)		 RGD PMID:21928377 PMID:22391157 RGD:11352824 RGD:11353789 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G CCND2 cyclin D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255 		JBrowse link
G CD44 CD44 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23098472 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107 		JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:mononuclear cell of bone marrow (human) RGD PMID:16115907 PMID:19197726 RGD:11354960 RGD:4892295 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G CD9 CD9 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576 		JBrowse link
G CDH1 cadherin 1 disease_progression ISO DNA:hypermethylation:promoter: RGD PMID:15863205 RGD:11252161 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO DNA:deletion: : RGD PMID:9171997 RGD:10450601 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression ISO mRNA,protein:altered expression:bone marrow:
DNA:deletion: :		 RGD PMID:11064355 PMID:11697625 RGD:11251749 RGD:11252080 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B susceptibility
disease_progression
treatment		 ISO DNA:hypermethylation: :
DNA:deletion: :
DNA:hypermethylation:promoter:
mRNA:decreased expression:granulocyte,monocyte:		 RGD PMID:9001419 PMID:11064355 PMID:14681685 PMID:15863205 PMID:25616284 More... RGD:11251739 RGD:11251749 RGD:11252161 RGD:11252164 RGD:11252167 RGD:11252196 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:11242107 PMID:12661007 PMID:12692518 PMID:14726504 PMID:15575056 More... NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPD CCAAT enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234736 NCBI chr35:74,994...77,816 JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator disease_progression ISO RGD PMID:23167276 RGD:11341679 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095 		JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:16361549 RGD:4892644 NCBI chr 7:25,620...32,954
Ensembl chr 7:26,316...33,427 		JBrowse link
G CHIC2 cysteine rich hydrophobic domain 2 ISO OMIM NCBI chr13:46,558,657...46,606,226
Ensembl chr13:46,560,009...46,607,959 		JBrowse link
G CHMP5 charged multivesicular body protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17708794 NCBI chr11:50,363,488...50,376,081 JBrowse link
G CNR2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15039279 NCBI chr 2:75,640,636...75,662,000
Ensembl chr 2:75,658,999...75,660,126 		JBrowse link
G CREBBP CREB binding protein ISO DNA:translocations:intron:IVS2 (human) RGD PMID:12461753 RGD:734819 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:1390197 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:1826536 PMID:21441929 RGD:10449528 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959 		JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:7528855 PMID:10673519 RGD:11039033 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CSF3R colony stimulating factor 3 receptor susceptibility
disease_progression		 ISO associated with Severe Congenital Neutropenia;DNA:nonsense mutation:cds:
ClinVar Annotator: match by term: Acute myelogenous leukemia		 RGD
ClinVar		 PMID:9001427 PMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 More... RGD:10450468 RGD:10450487 NCBI chr15:5,818,985...5,832,455
Ensembl chr15:5,822,025...5,831,882 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO DNA:SNP:3'UTR:rs3087243(human) RGD PMID:19092854 RGD:11344911 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874 		JBrowse link
G CTNNA1 catenin alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:26,273,322...26,459,497
Ensembl chr11:26,143,013...26,459,091 		JBrowse link
G CTSH cathepsin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 3:58,103,284...58,113,958
Ensembl chr 3:58,103,291...58,113,718 		JBrowse link
G CTSZ cathepsin Z ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr24:43,743,291...43,750,154
Ensembl chr24:43,743,294...43,754,424 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment
disease_progression		 ISO RGD PMID:24035716 PMID:26031918 RGD:11352265 RGD:11352273 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association
disease_progression		 ISO DNA:SNP: :4889A>G (human)
DNA:polymorphism: :6235T>C (human)
DNA:SNP: :6235T>C (human)		 RGD PMID:15996939 PMID:19456854 RGD:10769358 RGD:11352736 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP2B6 cytochrome P450 2B11 susceptibility ISO DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 susceptibility
treatment		 ISO DNA:polymorphisms: :
DNA:SNP: :(rs16947)(human)		 RGD PMID:11037802 PMID:21518482 RGD:11352820 RGD:11352828 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298 		JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19874806 NCBI chr 1:72,278,939...72,448,907
Ensembl chr 1:72,280,103...72,447,822 		JBrowse link
G DDX41 DEAD-box helicase 41 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:25920683 PMID:26712909 PMID:28547672 PMID:30963592 More... NCBI chr 4:35,854,382...35,859,853
Ensembl chr 4:35,854,597...35,859,852 		JBrowse link
G DHX15 DEAH-box helicase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 PMID:29163777 NCBI chr 3:85,549,946...85,609,598
Ensembl chr 3:85,549,981...85,609,612 		JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein treatment ISO DNA:hypermethylation:promoter: RGD PMID:27168825 RGD:11252164 NCBI chr23:7,813,305...7,889,322
Ensembl chr23:7,813,546...7,889,324 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA:increased expression:CD34+ bone marrow cells RGD PMID:11222358 RGD:9588667 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha disease_progression
treatment
susceptibility		 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:exon:p.R882 (human)
DNA:mutation::
DNA:hypomethylation: :
associated with Myelodysplastic Syndromes; DNA:mutations:cds:		 OMIM
ClinVar
RGD		 PMID:21067377 PMID:21415852 PMID:21518476 PMID:22160010 PMID:22722925 More... RGD:11041120 RGD:11041121 RGD:11041122 RGD:11041123 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression
susceptibility		 ISO DNA:SNP:promoter: C>T46359(human)
mRNA:increased expression:CD34+ bone marrow cells
DNA:SNPs,haplotype: :rs1569686,rs2424908, rs6087990, rs6119954(human)		 RGD PMID:11222358 PMID:16194411 PMID:23251566 PMID:24069326 RGD:9588667 RGD:9589071 RGD:9589103 RGD:9589108 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G EHD3 EH domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:24,828,289...24,854,990
Ensembl chr17:24,828,372...24,853,400 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:24532712 RGD:9589168 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr16:27,389,850...27,410,154
Ensembl chr16:27,390,181...27,410,110 		JBrowse link
G ENAH ENAH actin regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr 7:39,105,024...39,250,126
Ensembl chr 7:39,105,039...39,247,595 		JBrowse link
G ENO2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr27:38,120,404...38,128,543
Ensembl chr27:38,119,413...38,129,182 		JBrowse link
G EPHX1 epoxide hydrolase 1 no_association ISO DNA:SNPs:exon:rs1051740, rs2234922 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism
DNA:missense mutations:exon:p.Y113H, p.H139R (human)		 RGD
CTD		 PMID:11849215 PMID:20731606 PMID:22200898 PMID:29605894 RGD:11252114 RGD:11252115 RGD:11252119 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit no_association
treatment		 ISO DNA:SNP: :p.Q504K (human)
DNA:polymorphism: :p.R399Q (human)		 RGD PMID:16507781 PMID:18604718 PMID:20141440 PMID:21942242 PMID:23397959 RGD:11252170 RGD:11252171 RGD:11252173 RGD:11252179 RGD:11252193 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association
disease_progression		 ISO associated with Myeloproliferative Disorders;DNA:polymorphism: :p.K751Q (rs13181) (human)
DNA:SNPs, haplotypes: :p.D312N, p.K751Q (human)		 RGD PMID:20141440 PMID:21394217 PMID:22496165 PMID:23397959 RGD:11252173 RGD:11252193 RGD:11252198 RGD:11252209 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
G ERG ETS transcription factor ERG ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr31:33,456,902...33,562,704
Ensembl chr31:33,497,209...33,515,272 		JBrowse link
G ETV6 ETS variant transcription factor 6 ISO ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:15806161 PMID:25581430 PMID:25741868 PMID:25807284 PMID:31248877 More... NCBI chr27:34,351,206...34,587,060
Ensembl chr27:34,343,390...34,587,060 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility
disease_progression		 ISO DNA:mutations:cds:multiple (human)
mRNA:increased expression:bone marrow, mononuclear cell (human)		 RGD PMID:21125401 PMID:22677129 PMID:23099237 RGD:10450874 RGD:10450876 RGD:10450887 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:2617479 RGD:11340207 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G FADD Fas associated via death domain disease_progression ISO RGD PMID:15520222 RGD:11341799 NCBI chr18:48,087,447...48,094,497 JBrowse link
G FANCA FA complementation group A ISO DNA, mRNA:deletions, decreased expression: :multiple RGD PMID:14749703 RGD:11344889 NCBI chr 5:63,778,149...63,838,869
Ensembl chr 5:63,778,212...63,838,823 		JBrowse link
G FANCC FA complementation group C susceptibility ISO DNA:polymorphism:cds:p.S26F (human) RGD PMID:12670332 RGD:11046259 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506 		JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO DNA:polymorphism, haplotype:promoter:-1377 G>A, -670 G>A (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:7579353 PMID:8870373 PMID:12907599 RGD:11049150 RGD:11049452 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr 8:29,083,538...29,135,915
Ensembl chr 8:29,084,531...29,133,391 		JBrowse link
G FERMT3 FERM domain containing kindlin 3 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr18:52,833,954...52,851,775
Ensembl chr18:52,834,001...52,851,667 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment ISO RGD PMID:22683780 PMID:23777766 PMID:27005999 RGD:11352310 RGD:11352665 RGD:11352670 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G FHL2 four and a half LIM domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:37,997,912...38,065,633
Ensembl chr10:37,997,942...38,065,330 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment
disease_progression		 ISO ClinVar Annotator: match by term: Acute myeloid leukemia | ClinVar Annotator: match by term: Leukemia, acute myeloid, reduced survival in, somatic
DNA:mutations:cds:
DNA:duplication mutation:cds:		 OMIM
ClinVar
RGD		 PMID:11091200 PMID:11290608 PMID:11442493 PMID:12384447 PMID:14604974 More... RGD:11049467 RGD:11049482 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FOXO1 forkhead box O1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G FXYD6 FXYD domain containing ion transport regulator 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:15,801,790...15,807,601
Ensembl chr 5:15,771,390...15,807,601 		JBrowse link
G GAS2L1 growth arrest specific 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr26:22,615,531...22,620,605
Ensembl chr26:22,615,319...22,621,311 		JBrowse link
G GATA1 GATA binding protein 1 disease_progression ISO RGD PMID:7579412 RGD:10450754 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303 		JBrowse link
G GATA2 GATA binding protein 2 disease_progression ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia | ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to OMIM
ClinVar
RGD		 PMID:4508672 PMID:8701948 PMID:20040766 PMID:21242295 PMID:21670465 More... RGD:11049510 RGD:11049515 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:c.107G>A(rs34631763)(human)		 CTD
RGD		 PMID:17330099 PMID:20075157 RGD:11040450 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812 		JBrowse link
G GPATCH1 G-patch domain containing 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:119,009,605...119,052,676
Ensembl chr 1:119,009,609...119,053,140 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO protein:increased expression:plasma: RGD PMID:6589021 RGD:11051848 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316 		JBrowse link
G GPX1 glutathione peroxidase 1 susceptibility
disease_progression
treatment		 ISO DNA:polymorphism: :p.P198L (human)
DNA:SNP: :c.599C>T (rs1050450) (human)		 RGD PMID:22930375 PMID:26823947 PMID:26950655 RGD:11061561 RGD:11061784 RGD:11352817 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G GSKIP GSK3B interacting protein ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,110,659...65,131,205
Ensembl chr 8:65,111,414...65,129,622 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24191316 RGD:11059506 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:cds:p.I105V(human)
chemotherapy-induced;		 RGD PMID:11553769 PMID:11906705 PMID:21729529 RGD:10755328 RGD:10755420 RGD:10755422 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G GTF2I general transcription factor IIi ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 6:5,726,652...5,840,740
Ensembl chr 6:5,727,665...5,811,965 		JBrowse link
G H1-0 H1.0 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:26,827,748...26,829,909
Ensembl chr10:26,829,089...26,829,673 		JBrowse link
G H1-2 H1.2 linker histone, cluster member ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr35:24,009,304...24,011,602 JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA:increased expression:brain, spleen RGD PMID:19268504 RGD:10755700 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HOXA9 homeobox A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22541086 NCBI chr14:40,336,829...40,340,533
Ensembl chr14:40,337,999...40,339,923 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Acute myelogenous leukemia ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576 		JBrowse link
G ID2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:5,956,924...5,958,833 JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO DNA:mutation:cds:p.R132(human)
ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:SNP::105C>T (rs11554137)(human)		 RGD
ClinVar		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20368543 More... RGD:11522718 RGD:11522721 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO DNA:mutation:cds:p.R172(human)
ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:mutation:cds:p.R140 (human)		 RGD
ClinVar		 PMID:20171147 PMID:20368543 PMID:20847235 PMID:20946881 PMID:21250968 More... RGD:11522718 RGD:11522721 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496 		JBrowse link
G IFI30 IFI30 lysosomal thiol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr20:44,819,862...44,823,261
Ensembl chr20:44,819,893...44,823,342 		JBrowse link
G IL10 interleukin 10 disease_progression ISO RGD PMID:23357299 RGD:11046264 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL1A interleukin 1 alpha treatment ISO RGD PMID:2460157 RGD:11051965 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL4R interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11918534 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G IL6 interleukin 6 treatment
disease_progression		 ISO human protein in a rat model RGD PMID:8892684 PMID:23357299 RGD:11046264 RGD:11062010 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:826,711...1,192,340
Ensembl chr19:850,784...1,186,498 		JBrowse link
G INSL6 insulin like 6 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 More... NCBI chr 1:93,457,854...93,474,777
Ensembl chr 1:93,459,945...93,474,793 		JBrowse link
G ITGAV integrin subunit alpha V treatment ISO RGD PMID:23770013 RGD:10755448 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430 		JBrowse link
G ITGB3 integrin subunit beta 3 treatment ISO RGD PMID:23770013 RGD:10755448 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
G JAK1 Janus kinase 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:21436584 More... NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK2 Janus kinase 2 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 More... NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G KAT6A lysine acetyltransferase 6A ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr16:23,604,629...23,717,047
Ensembl chr16:23,604,200...23,724,252 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:7479840 PMID:7513208 PMID:7691885 PMID:8589724 PMID:9657776 More... NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G KLF1 Kruppel like factor 1 disease_progression ISO RGD PMID:19097174 RGD:10769344 NCBI chr20:49,295,097...49,298,668
Ensembl chr20:49,295,195...49,298,602 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO DNA:rearrangements
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:8361504 PMID:10339604 PMID:26237430 RGD:1625285 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G KMT2B lysine methyltransferase 2B susceptibility ISO RGD PMID:25079327 RGD:9588599 NCBI chr 1:116,894,024...116,913,464
Ensembl chr 1:116,893,074...116,913,472 		JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:24794707 NCBI chr16:15,962,045...16,117,601
Ensembl chr16:15,963,901...16,158,408 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:7773929 More... NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LOC100686511 myeloid cell surface antigen CD33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12921496 NCBI chr 1:105,722,187...105,731,616 JBrowse link
G LOC478670 LIM domain containing preferred translocation partner in lipoma ISO ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:25741868 NCBI chr34:20,538,580...21,157,978
Ensembl chr34:20,632,193...21,142,914 		JBrowse link
G LOC607874 cystatin-C-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr23:49,562...53,618 JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:65,690,806...65,822,166
Ensembl chr11:65,692,973...65,822,312 		JBrowse link
G LRP3 LDL receptor related protein 3 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,924,195...118,934,687
Ensembl chr 1:118,926,861...118,929,769 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220 		JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16094422 NCBI chr20:49,109,358...49,113,911 JBrowse link
G MDM2 MDM2 proto-oncogene disease_progression ISO RGD PMID:11064355 RGD:11251749 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G MECOM MDS1 and EVI1 complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:30472098 NCBI chr34:33,747,495...34,299,389
Ensembl chr34:33,748,843...34,299,276 		JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:polymorphisms:cds:p.M694V,E148Q(human) RGD PMID:22351163 RGD:11531114 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:increased expression:blood
miRNA:decreased expression:peripheral blood mononuclear cell		 RGD PMID:26923190 PMID:28989535 RGD:24922214 RGD:25671477 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833 		JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor ISO ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:25741868 NCBI chr 2:11,349,864...11,607,194
Ensembl chr 2:11,349,856...11,596,398 		JBrowse link
G MN1 MN1 proto-oncogene, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr26:21,216,912...21,261,518
Ensembl chr26:21,216,837...21,261,031 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:17156840 RGD:10449408 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G(human) RGD PMID:18774170 RGD:11075096 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
G MX1 MX dynamin like GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr31:35,898,206...35,929,802
Ensembl chr31:35,860,590...35,951,350 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25956709 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G MYH11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr 6:28,041,330...28,157,277
Ensembl chr 6:28,041,318...28,262,184 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr29:19,253,849...19,471,640
Ensembl chr29:19,222,842...19,545,371 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:110,543,140...110,569,168
Ensembl chr 1:110,543,247...110,569,143 		JBrowse link
G NF1 neurofibromin 1 disease_progression
severity		 ISO CTD Direct Evidence: marker/mechanism
DNA:deletion: :		 CTD
RGD		 PMID:12518368 PMID:21441929 PMID:23460398 PMID:25822087 RGD:12754447 RGD:12789444 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382 		JBrowse link
G NOS3 nitric oxide synthase 3 disease_progression ISO DNA:polymorphgism: : 894 G>T(human) RGD PMID:24684492 RGD:11533640 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NPM1 nucleophosmin 1 disease_progression
onset		 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:mutation:exon:		 OMIM
ClinVar
RGD		 PMID:15659725 PMID:17957027 PMID:19657110 PMID:20026798 PMID:21441929 More... RGD:11049474 RGD:11070453 RGD:11534990 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO DNA:SNP: :609C>T (human) RGD PMID:19456854 RGD:10769358 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO DNA:missense mutation:cds:
ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia		 RGD
ClinVar		 PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 More... RGD:11070616 RGD:11535045 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 severity ISO DNA:translocations:multiple (human)
ClinVar Annotator: match by term: Acute myeloid leukemia		 RGD
ClinVar		 PMID:12807965 PMID:15942875 PMID:17565729 PMID:23190751 PMID:23630019 More... RGD:9590149 NCBI chr 4:36,058,351...36,214,254
Ensembl chr 4:36,063,134...36,210,999 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29119387 NCBI chr 3:51,131,470...51,491,112
Ensembl chr 3:51,138,751...51,513,024 		JBrowse link
G NUP214 nucleoporin 214 ISO OMIM NCBI chr 9:52,840,300...52,943,785
Ensembl chr 9:52,841,096...52,947,770 		JBrowse link
G NUP98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020 		JBrowse link
G PDCD1 programmed cell death 1 treatment ISO RGD PMID:26712908 RGD:41410789 NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723 		JBrowse link
G PDE4B phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein susceptibility ISO DNA:inversion: :inv(11)(q14q23) OMIM
RGD		 PMID:12461747 RGD:1600760 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616 		JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr  X:42,072,495...42,077,741
Ensembl chr  X:42,073,457...42,077,543 		JBrowse link
G PLCB1 phospholipase C beta 1 severity ISO mRNA:increased expression:blood (human) RGD PMID:20516454 RGD:11535940 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539 		JBrowse link
G POU4F1 POU class 4 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr22:31,992,657...31,997,066 JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO mRNA:increased expression:bone marrow, mononuclear cell (human) RGD PMID:20376794 RGD:11535023 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PSIP1 PC4 and SFRS1 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:35,746,064...35,788,473
Ensembl chr11:35,747,341...35,789,110 		JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:28873162 PMID:32321774 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 More... NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PVR PVR cell adhesion molecule ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:110,692,906...110,713,209
Ensembl chr 1:110,697,911...110,754,296 		JBrowse link
G PXDN peroxidasin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:834,625...891,551
Ensembl chr17:836,434...875,117 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494 		JBrowse link
G RHPN2 rhophilin Rho GTPase binding protein 2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:119,061,637...119,119,470
Ensembl chr 1:119,061,562...119,119,468 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr24:47,219,977...47,248,791 JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia | ClinVar Annotator: match by term: Leukemia, acute myeloid, m0 subtype OMIM
ClinVar		 PMID:10068652 PMID:10508512 PMID:11276260 PMID:12200707 PMID:12377125 More... NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr29:37,156,861...37,289,934
Ensembl chr29:37,158,659...37,297,879 		JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229
G S100A10 S100 calcium binding protein A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:60,984,138...60,994,915 JBrowse link
G S100A8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21971985 NCBI chr 7:43,540,667...43,541,604
Ensembl chr 7:43,501,989...43,541,604 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 severity ISO human cell line in mouse model RGD PMID:30474474 RGD:149735523 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902 		JBrowse link
G SEPTIN9 septin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10339604 NCBI chr 9:3,495,764...3,571,755
Ensembl chr 9:3,448,793...3,616,732 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:21909114 PMID:21995386 PMID:23395771 PMID:23634996 PMID:26619011 NCBI chr37:6,922,150...6,962,474
Ensembl chr37:6,924,047...6,962,896 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:26619011 NCBI chr18:51,197,924...51,212,397
Ensembl chr18:51,197,939...51,212,354 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:27,086,431...27,196,601
Ensembl chr 1:27,087,361...27,196,521 		JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar		 PMID:25741868 NCBI chr20:55,279,622...55,311,579
Ensembl chr20:55,279,621...55,311,536 		JBrowse link
G SLC7A10 solute carrier family 7 member 10 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,908,087...118,923,034
Ensembl chr 1:118,907,184...118,923,215 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO DNA:hypermethylation: : RGD PMID:12759928 RGD:150573811 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G SOD2 superoxide dismutase 2 disease_progression ISO protein:increased expression:serum RGD PMID:1596865 PMID:16769586 RGD:11035286 RGD:11035289 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:57,659,541...57,682,147
Ensembl chr 4:57,659,650...57,681,711 		JBrowse link
G SPI1 Spi-1 proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822087 NCBI chr 2:37,199,890...37,213,710
Ensembl chr 2:37,203,609...37,208,858 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 severity ISO DNA:mutations:multiple (human) RGD PMID:22431577 RGD:11039017 NCBI chr 9:4,028,414...4,032,371
Ensembl chr 9:4,028,482...4,030,793 		JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 ISO mRNA:decreased expression: (human) RGD PMID:22722453 RGD:11039059 NCBI chr 2:71,418,626...71,434,140
Ensembl chr 2:71,394,037...71,471,997 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19796711 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G SVIL supervillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:16,004,160...16,234,434
Ensembl chr 2:16,004,951...16,174,218 		JBrowse link
G SYNGR1 synaptogyrin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:25,685,079...25,735,940
Ensembl chr10:25,687,633...25,713,300 		JBrowse link
G TCEA2 transcription elongation factor A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr24:47,508,161...47,512,399
Ensembl chr24:47,508,136...47,537,250 		JBrowse link
G TCL1A TCL1 family AKT coactivator A ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar
G TCN2 transcobalamin 2 ISO protein:increased expression:: RGD PMID:1059479 RGD:11060122 NCBI chr26:23,693,664...23,710,342
Ensembl chr26:23,693,773...23,709,832 		JBrowse link
G TEK TEK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:19340004 PMID:28492532 NCBI chr11:45,278,375...45,377,300
Ensembl chr11:45,278,891...45,409,093 		JBrowse link
G TERT telomerase reverse transcriptase disease_progression ISO ClinVar Annotator: match by term: Acute myeloid leukemia | ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to OMIM
ClinVar
RGD		 PMID:15814878 PMID:17460043 PMID:18042801 PMID:18460650 PMID:18753630 More... RGD:11038655 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 disease_progression ISO DNA:deletions RGD PMID:23389918 PMID:25200248 RGD:11038681 RGD:11038682 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO DNA:hypermethylation:promoter: RGD PMID:22052167 RGD:11060127 NCBI chr14:19,399,259...19,403,890
Ensembl chr14:19,399,720...19,403,708 		JBrowse link
G TFR2 transferrin receptor 2 disease_progression ISO RGD PMID:15015967 RGD:11062090 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158 		JBrowse link
G TGM6 transglutaminase 6 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:21106500 PMID:23206699 PMID:24755948 PMID:25253745 PMID:26467025 More... NCBI chr24:18,698,016...18,721,975
Ensembl chr24:18,700,099...18,721,930 		JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia ClinVar PMID:20923864 PMID:25741868 PMID:28492532 NCBI chr17:34,512,753...34,527,208
Ensembl chr17:34,512,792...34,523,692 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:12780785 NCBI chr34:36,719,249...36,734,989
Ensembl chr34:36,670,849...36,735,060 		JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 PMID:10512160 PMID:11918534 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355 		JBrowse link
G TNFSF9 TNF superfamily member 9 ISO protein:increased expression:serum (human) RGD PMID:11564827 RGD:2317350 NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706 		JBrowse link
G TP53 tumor protein p53 treatment
disease_progression		 ISO DNA:mutations: :
ClinVar Annotator: match by term: Acute myelogenous leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:mutation: :		 RGD
ClinVar		 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 More... RGD:11057925 RGD:11073714 RGD:11075071 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TRH thyrotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr20:5,219,495...5,222,914
Ensembl chr20:5,219,594...5,222,866 		JBrowse link
G TRIO trio Rho guanine nucleotide exchange factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr34:271,572...505,656
Ensembl chr34:272,290...505,636 		JBrowse link
G TSC1 TSC complex subunit 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:51,409,307...51,459,546
Ensembl chr 9:51,425,937...51,454,677 		JBrowse link
G TSC2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19250671 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
G TUBB2A tubulin beta 2A class IIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr35:3,448,402...3,450,783
Ensembl chr35:3,448,435...3,452,091 		JBrowse link
G TYMS thymidylate synthetase susceptibility ISO DNA:repeats,insertion/deletion:5'UTR, 3'UTR: RGD PMID:18774170 RGD:11075096 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
G U2AF1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr31:37,263,265...37,276,710 JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO DNA:SNP,haplotype: :(rs3025039),(rs699947),(rs833061)(human) RGD PMID:17983459 RGD:13432134 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G VOPP1 VOPP1 WW domain binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr18:6,282,050...6,387,687
Ensembl chr18:6,282,426...6,386,703 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr  X:50,839,979...50,881,684
Ensembl chr  X:50,803,330...50,881,618 		JBrowse link
G WDR88 WD repeat domain 88 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,962,602...119,007,836
Ensembl chr 1:118,962,605...119,007,759 		JBrowse link
G WT1 WT1 transcription factor ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:24374862 PMID:24422723 PMID:24521058 PMID:24659740 PMID:24667279 More... NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr20:55,517,531...55,527,071
Ensembl chr20:55,505,916...55,523,736 		JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase ISO RGD PMID:12738986 RGD:727221 NCBI chr18:37,762,200...37,809,070 JBrowse link
G ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 ISO associated with aging
DNA:missense mutations:multiple (human)		 RGD PMID:25550361 PMID:32027246 RGD:151232299 RGD:151347178 NCBI chr  X:12,046,163...12,073,617
Ensembl chr  X:12,046,921...12,073,440 		JBrowse link
Acute Myelomonocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP26 Rho GTPase activating protein 26 ISO juvenile myelomonocytic leukemia, OMIM:607785 translocation t(5;11)(q31;q23) fusing ARHGAP26 to MLL in one allele and point mutation A1255G/Asn417Ser or one of two insertions in second allele RGD PMID:10908648 RGD:1599311 NCBI chr 2:37,627,448...38,045,589
Ensembl chr 2:37,626,698...38,040,079 		JBrowse link
G CBFB core-binding factor subunit beta susceptibility ISO DNA:inversion: :inv(16)(p13q22)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:8351518 PMID:10958941 RGD:1599543 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:14681685 RGD:11252167 NCBI chr11:41,259,627...41,264,832 JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment ISO RGD PMID:22187040 RGD:11049503 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G GMPS guanine monophosphate synthase ISO treatment-related acute type M4 myeloid leukemia; chromosomal translocation resulted in a fusion of MLL and GMPS genes RGD PMID:11110714 RGD:1598998 NCBI chr23:49,569,571...49,645,999
Ensembl chr23:49,569,531...49,699,199 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G MYH11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10958941 NCBI chr 6:28,041,330...28,157,277
Ensembl chr 6:28,041,318...28,262,184 		JBrowse link
acute promyelocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr11:60,761,669...60,869,753
Ensembl chr11:60,761,655...60,890,496 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12556562 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23563754 NCBI chr30:23,223,413...23,271,893
Ensembl chr30:23,225,331...23,269,076 		JBrowse link
G ASXL1 ASXL transcriptional regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr24:21,725,126...21,804,745
Ensembl chr24:21,661,059...21,802,815 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27770503 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G CD44 CD44 molecule ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16208414 PMID:17349212 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B disease_progression ISO DNA:hyprmethylation:promoter: RGD PMID:12750706 RGD:11252187 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16788101 PMID:26285909 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon ISO CTD Direct Evidence: therapeutic CTD PMID:16788101 NCBI chr 8:3,423,046...3,425,595
Ensembl chr 8:3,423,040...3,425,217 		JBrowse link
G DAPK2 death associated protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28978663 NCBI chr30:28,440,616...28,565,089
Ensembl chr30:28,441,161...28,565,566 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:10726043 PMID:16206674 RGD:11340216 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17454189 PMID:24160850 PMID:26285909 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FNDC3B fibronectin type III domain containing 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28314734 NCBI chr34:36,373,966...36,640,851
Ensembl chr34:36,302,386...36,637,583 		JBrowse link
G GLI1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982 		JBrowse link
G GLI2 GLI family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658 		JBrowse link
G GPHN gephyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr 8:40,585,625...41,204,007
Ensembl chr 8:40,585,883...41,203,245 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496 		JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IL17A interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25583766 NCBI chr 4:5,242,225...5,249,371
Ensembl chr 4:5,244,869...5,247,247 		JBrowse link
G ITGAL integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986 		JBrowse link
G ITGAM integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286 		JBrowse link
G ITGAX integrin subunit alpha X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:16,898,143...16,927,270
Ensembl chr 6:16,808,971...16,996,286 		JBrowse link
G ITGB2 integrin subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) severity ISO mRNA:decreased expression:peripheral blood, bone marrow, mononuclear cells (human) RGD PMID:24796963 RGD:9588539 NCBI chr18:15,240,631...15,332,850
Ensembl chr18:15,239,994...15,332,828 		JBrowse link
G LAT2 linker for activation of T cells family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32587277 NCBI chr 6:6,160,939...6,175,271
Ensembl chr 6:6,161,542...6,173,294 		JBrowse link
G LEP leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LOC487387 RAP1 GTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22614916 NCBI chr 2:77,509,592...77,554,620
Ensembl chr 2:77,527,914...77,544,205 		JBrowse link
G LTC4S leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr11:1,893,927...1,897,028
Ensembl chr11:1,894,380...1,897,752 		JBrowse link
G ME1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr12:43,623,413...43,793,590
Ensembl chr12:43,624,945...43,828,775 		JBrowse link
G MIR15A microRNA mir-15a ISO CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr22:1,846,880...1,846,938
Ensembl chr22:1,846,866...1,846,960 		JBrowse link
G MIR16-1 microRNA mir-16-1 ISO CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr22:1,847,020...1,847,084
Ensembl chr22:1,847,007...1,847,093 		JBrowse link
G MTARC2 mitochondrial amidoxime reducing component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr38:15,426,884...15,451,701
Ensembl chr38:15,426,666...15,451,136 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor onset ISO mRNA:increased expression:promyelocyte: RGD PMID:21059853 RGD:11532756 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:24296270 RGD:40907062 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995 		JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14508522 PMID:26285909 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 ISO OMIM NCBI chr21:26,000,579...26,076,281
Ensembl chr21:26,037,095...26,075,549 		JBrowse link
G PLAT plasminogen activator, tissue type ISO protein:increased expression:leukocyte (human) RGD PMID:10861807 RGD:11541060 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PML PML nuclear body scaffold ISO human PML/RARA gene fusion in a mouse model
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:8616088 PMID:9122233 PMID:10742073 PMID:14706140 PMID:16788101 More... RGD:41404695 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:bone marrow (human) RGD PMID:18815192 RGD:11535037 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17712046 NCBI chr 9:15,180,940...15,203,035
Ensembl chr 9:15,181,393...15,200,683 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32417439 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G RARA retinoic acid receptor alpha ISO OMIM NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459 		JBrowse link
G RETN resistin ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr20:52,434,148...52,435,627
Ensembl chr20:52,434,271...52,435,624 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32417439 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO CTD Direct Evidence: therapeutic CTD PMID:33120864 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955 		JBrowse link
G SMO smoothened, frizzled class receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536 		JBrowse link
G THBD thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16206674 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649 		JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute promyelocytic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr17:34,512,753...34,527,208
Ensembl chr17:34,512,792...34,523,692 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO ClinVar Annotator: match by term: Dna topoisomerase II, resistance to inhibition of, by amsacrine ClinVar PMID:1651812 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496 		JBrowse link
G TRIB3 tribbles pseudokinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32929351 NCBI chr24:20,450,281...20,461,141
Ensembl chr24:20,451,001...20,457,510 		JBrowse link
G WT1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8387545 PMID:23208507 RGD:1599922 NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628 		JBrowse link
adult T-cell leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16497974 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BMP6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18688853 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr23:3,844,072...3,847,770
Ensembl chr23:3,844,173...3,845,255 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
G CD163 CD163 molecule disease_progression ISO protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106 		JBrowse link
G CD274 CD274 molecule disease_progression ISO RGD PMID:27418641 RGD:41412177 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522 		JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854 		JBrowse link
G CD68 CD68 molecule disease_progression ISO protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr 5:32,500,899...32,503,355
Ensembl chr 5:32,501,380...32,503,183 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380 		JBrowse link
G CD86 CD86 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 4:59,435,530...59,485,591
Ensembl chr 4:59,435,764...59,483,475 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2B casein kinase 2 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874 		JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO protein:increased expression:peripheral blood mononuclear cell:
DNA:polymorphism:promoter: -670 G>A(human)		 RGD PMID:7513372 PMID:17962369 RGD:11049147 RGD:11049453 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FOXP3 forkhead box P3 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23797717 PMID:23962110 RGD:38456007 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G GPR183 G protein-coupled receptor 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr22:49,332,665...49,347,721
Ensembl chr22:49,333,188...49,347,593 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr14:39,498,805...39,509,034
Ensembl chr14:39,500,897...39,508,952 		JBrowse link
G ICOS inducible T cell costimulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,663,839...12,735,266
Ensembl chr37:12,670,999...12,733,458 		JBrowse link
G IFNG interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:8800741 PMID:23962110 RGD:10755707 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IKZF2 IKAROS family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:20,508,647...20,662,549
Ensembl chr37:20,516,239...20,661,298 		JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:8704212 PMID:23962110 RGD:11049460 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G IL5 interleukin 5 disease_progression ISO protein:increased expression:serum RGD PMID:16425276 RGD:11354942 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum (human) RGD PMID:10374863 RGD:11060275 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IRF4 interferon regulatory factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G JAK3 Janus kinase 3 ISO DNA:missense mutations: :p.L156P, p.R172Q, p.E183G (human) RGD PMID:21821710 RGD:11531131 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G MYB MYB proto-oncogene, transcription factor disease_progression ISO mRNA:splice variants:CD4+ T cell: RGD PMID:27307595 RGD:11532670 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969 		JBrowse link
G NOTCH1 notch receptor 1 ISO DNA:mutations:multiple (human) RGD PMID:16707600 RGD:1580759 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:21586752 RGD:11535055 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PRKCB protein kinase C beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24090995 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TAL2 TAL bHLH transcription factor 2 ISO RGD PMID:1763056 RGD:1599285 NCBI chr11:61,425,927...61,484,525
Ensembl chr11:61,456,727...61,482,348 		JBrowse link
G TERF2 telomeric repeat binding factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17643074 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342 		JBrowse link
G TLX1 T cell leukemia homeobox 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:1683261 PMID:1717256 RGD:1599439 NCBI chr28:13,807,428...13,813,875
Ensembl chr28:13,807,720...13,813,849 		JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355 		JBrowse link
G TP73 tumor protein p73 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:53,482,239...53,532,399
Ensembl chr20:53,482,498...53,531,296 		JBrowse link
alpha-thalassemia myelodysplasia syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler ISO ClinVar Annotator: match by term: Acquired hemoglobin H disease | ClinVar Annotator: match by term: Alpha-thalassemia myelodysplasia syndrome OMIM
ClinVar		 PMID:9326931 PMID:10995512 PMID:12858175 PMID:16955409 PMID:20500465 More... NCBI chr  X:59,772,067...60,107,016
Ensembl chr  X:59,774,585...60,106,980 		JBrowse link
AMED syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide ISO ClinVar Annotator: match by term: AMED syndrome, digenic OMIM
ClinVar		 PMID:25741868 PMID:33355142 NCBI chr32:21,249,459...21,261,130
Ensembl chr32:21,249,739...21,265,048 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: BONE MARROW FAILURE SYNDROME 7, DIGENIC ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr26:9,319,109...9,361,021 JBrowse link
anaplastic large cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16151469 PMID:19503098 PMID:21345110 PMID:22155737 PMID:22920921 More... NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157164 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243 		JBrowse link
G IRF4 interferon regulatory factor 4 ISO DNA:translocation RGD PMID:18987657 RGD:11526155 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:12145210 RGD:1549449 NCBI chr20:49,358,904...49,360,746
Ensembl chr20:49,359,399...49,360,442 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17261581 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10908157 PMID:17261581 NCBI chr 2:84,185,445...84,225,986
Ensembl chr 2:84,186,961...84,232,675 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22155737
atypical chronic myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:15050920 RGD:11352668 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G SETBP1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23222956 NCBI chr 7:46,020,892...46,378,867
Ensembl chr 7:46,020,889...46,378,005 		JBrowse link
autosomal dominant sideroblastic anemia 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO ClinVar Annotator: match by term: Anemia, sideroblastic, 4 OMIM
ClinVar		 PMID:3653362 PMID:20817635 PMID:25741868 PMID:26491070 NCBI chr11:26,122,917...26,142,458
Ensembl chr11:26,121,499...26,142,434 		JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 8:64,383,203...64,392,886
Ensembl chr 8:64,383,227...64,383,841 		JBrowse link
G SLC25A38 solute carrier family 25 member 38 ISO ClinVar Annotator: match by term: Anemia, sideroblastic, 2, pyridoxine-refractory | ClinVar Annotator: match by term: Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive | ClinVar Annotator: match by term: Sideroblastic anemia pyridoxine-refractory autosomal recessive OMIM
ClinVar		 PMID:19412178 PMID:21393332 PMID:24323989 PMID:25326635 PMID:25512395 More... NCBI chr23:9,031,984...9,045,781
Ensembl chr23:9,032,000...9,045,788 		JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 ISO ClinVar Annotator: match by term: Sideroblastic anemia 3 OMIM
ClinVar		 PMID:17485548 PMID:20364084 PMID:25342667 PMID:25741868 PMID:26100117 More... NCBI chr 8:64,383,203...64,392,886
Ensembl chr 8:64,383,227...64,383,841 		JBrowse link
Autosomal Sideroblastic Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARSA arylsulfatase A ISO ClinVar Annotator: match by term: Autosomal recessive sideroblastic anemia ClinVar PMID:25741868 NCBI chr10:16,691,927...16,694,346
Ensembl chr10:16,691,758...16,695,398 		JBrowse link
B-cell acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit ISO ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia ClinVar PMID:23623386 PMID:25741868 NCBI chr 6:29,193,192...29,226,935
Ensembl chr 6:29,196,421...29,226,887 		JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia ClinVar PMID:9536098 PMID:17576681 PMID:23656349 PMID:25741868 PMID:28492532 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382 		JBrowse link
G WT1 WT1 transcription factor ISO ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More... NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000 		JBrowse link
B-Cell Chronic Lymphocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 susceptibility ISO DNA:SNPs,haplotype: :rs1481012,rs2231142(human) RGD PMID:21918980 RGD:11080977 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G ACOXL acyl-CoA oxidase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr17:35,269,824...35,617,068
Ensembl chr17:35,269,501...35,617,335 		JBrowse link
G AICDA activation induced cytidine deaminase disease_progression ISO RGD PMID:21133730 RGD:11039455 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789 		JBrowse link
G APOE apolipoprotein E disease_progression ISO RGD PMID:18784741 RGD:11040549 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G ATM ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17968022 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207 		JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A ISO DNA:translocation:5' utr: (human) RGD PMID:11719382 RGD:11100004 NCBI chr10:60,589,298...60,691,997
Ensembl chr10:60,589,708...60,689,073 		JBrowse link
G BCL2 BCL2 apoptosis regulator severity
no_association
treatment		 ISO protein:increased expression:B cell (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-938C>A (human)		 RGD
CTD		 PMID:16960146 PMID:17296974 PMID:17959858 PMID:20001236 PMID:21750559 More... RGD:11522735 RGD:11526104 RGD:11526105 RGD:11526110 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BMF Bcl2 modifying factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr30:7,301,000...7,321,949
Ensembl chr30:7,274,174...7,322,034 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:12068308 PMID:12198537 PMID:12692057 PMID:12960123 PMID:14612909 More... NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G BTK Bruton tyrosine kinase treatment ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia RGD
ClinVar		 PMID:23045577 PMID:24869598 PMID:25741868 PMID:28492532 RGD:11040699 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G CBL Cbl proto-oncogene severity ISO mRNA,protein:increased expression:CD5+ B cell:
DNA:hypophosphorylation:CD5+ B cell:		 RGD PMID:17804547 RGD:11038803 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CCDC50 coiled-coil domain containing 50 ISO RGD PMID:19641524 RGD:9685139 NCBI chr34:23,168,594...23,243,221
Ensembl chr34:23,168,525...23,258,497 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20616215 RGD:5490532 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301 		JBrowse link
G CD40LG CD40 ligand ISO mouse-human chimeric gene in human RGD PMID:20882050 RGD:11352235 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CD5 CD5 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr18:55,216,415...55,235,567
Ensembl chr18:55,217,276...55,235,405 		JBrowse link
G CD79B CD79b molecule ISO protein:decreased expression:B lymphocyte, cell surface (human)
mRNA, protein:splice variants, alternative forms:exon 3 (human)
DNA:polymorphism:multiple (human)		 RGD PMID:9269755 PMID:10090943 PMID:10552962 RGD:11250403 RGD:151665190 RGD:151665202 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843 		JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:25179679 RGD:11354969 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr 3:54,405,140...54,499,614
Ensembl chr 3:54,405,717...54,500,221 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO protein:increased expression:T cell RGD PMID:15914560 PMID:16094420 RGD:11344923 RGD:11352246 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874 		JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 ISO RGD PMID:18077792 RGD:11251735 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA:decreased expression: B cell RGD PMID:15467427 RGD:9589146 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO DNA:SNP: :p.K751Q (rs13181) (human) RGD PMID:19484764 PMID:22739018 RGD:11252203 RGD:11252204 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr25:51,331,876...51,425,754
Ensembl chr25:51,332,409...51,425,449 		JBrowse link
G FAS Fas cell surface death receptor disease_progression ISO RGD PMID:12901972 RGD:11049461 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:25741868 PMID:26619011 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G GNAS GNAS complex locus disease_progression ISO DNA:polymorphism:393T>C (human) RGD PMID:17020971 RGD:1601379 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity ISO RGD PMID:7658704 RGD:11354983 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G IFNG interferon gamma susceptibility ISO DNA:polymorphism: :847A>T(human) RGD PMID:19757192 RGD:10755703 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IL10 interleukin 10 disease_progression
no_association		 ISO protein:increased expression:serum
DNA:SNPs: :rs1800890, rs4072227, rs17015865 (human)
DNA:SNPs: :multiple		 RGD PMID:10638947 PMID:19573080 PMID:22945689 RGD:11041895 RGD:11049165 RGD:11049174 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL19 interleukin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr 7:6,000,994...6,006,959
Ensembl chr 7:6,000,907...6,006,870 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:19074885 RGD:11051968 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta severity ISO DNA:SNP:promoter:-511C>T (human)
protein:decreased expression:plasma:		 RGD PMID:10870116 PMID:18271063 RGD:11051967 RGD:11522755 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:decreased expression:plasma: RGD PMID:10870116 RGD:11522755 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma:		 CTD
RGD		 PMID:10870116 PMID:18006695 RGD:11522755 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IRF4 interferon regulatory factor 4 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12079517 PMID:12393648 PMID:18758461 RGD:11526160 RGD:11530024 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G ITGA4 integrin subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21093051 NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More... NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G LOC100683403 NKG2-A/NKG2-B type II integral membrane protein-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr27:35,307,892...35,374,397 JBrowse link
G LOC478984 low affinity immunoglobulin gamma Fc region receptor III no_association ISO DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14563637 RGD:11352260 NCBI chr38:21,054,870...21,060,948 JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220 		JBrowse link
G MIR143 microRNA mir-143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR145 microRNA mir-145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO RGD PMID:19911856 RGD:2316994 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16706930 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:21179087 PMID:22931316 PMID:23215570 PMID:26619011 PMID:28492532 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11003599 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 severity ISO protein:increased expression:B cell (human) RGD PMID:12673718 RGD:11541127 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778 		JBrowse link
G PLCG2 phospholipase C gamma 2 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:24869598 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 1:16,469,793...16,472,910
Ensembl chr 1:16,469,793...16,472,910 		JBrowse link
G POLB DNA polymerase beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr16:23,306,359...23,335,352
Ensembl chr16:23,306,367...23,335,322 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr 8:69,846,311...69,969,409
Ensembl chr 8:69,846,446...69,967,578 		JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO protein:increased expression:mononuclear cell (human) RGD PMID:16620968 RGD:11535021 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PRKD2 protein kinase D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16314473 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 More... NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G QPCT glutaminyl-peptide cyclotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr17:29,700,422...29,741,652
Ensembl chr17:29,716,378...29,741,221 		JBrowse link
G RBL2 RB transcriptional corepressor like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr 2:62,263,974...62,315,371
Ensembl chr 2:62,265,293...62,315,425 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:23634996 PMID:25741868 PMID:26619011 NCBI chr37:6,922,150...6,962,474
Ensembl chr37:6,924,047...6,962,896 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:26619011 NCBI chr18:51,197,924...51,212,397
Ensembl chr18:51,197,939...51,212,354 		JBrowse link
G SP140 SP140 nuclear body protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr25:42,459,013...42,527,141
Ensembl chr25:42,459,084...42,527,093 		JBrowse link
G TERT telomerase reverse transcriptase disease_progression ISO RGD PMID:17344921 RGD:11038662 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TFRC