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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:brain ischemia
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Accession:DOID:2316 term browser browse the term
Definition:Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Synonyms:exact_synonym: Brain Ischemias;   Cerebral Hypoperfusion;   Cerebral Ischemias;   Ischaemic encephalopathy;   Ischemic Encephalopathies;   cerebral ischemia;   ischemic encephalopathy
 primary_id: MESH:D002545
 alt_id: RDO:0005166
For additional species annotation, visit the Alliance of Genome Resources.


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brain ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B IEP RGD PMID:15049514 RGD:1598554 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP mRNA:increased expression:brain RGD PMID:17073862 RGD:9681750 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Add3 adducin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adk adenosine kinase ISO RGD PMID:21427729, PMID:17457365 RGD:6482652, RGD:6482655 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA:increased expression:pyramidal cell, hippocampus RGD PMID:12618340 RGD:1625348 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:18301954 RGD:2313032 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akap1 A-kinase anchoring protein 1 IEP protein:altered expression:parietal cortex, hippocampus (rat) RGD PMID:18323779 RGD:2313128 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP RGD PMID:21334414 RGD:14348963 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IEP protein:decreased serine phosphorylation:cerebral cortex RGD PMID:21596097 RGD:5509066 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin ISO CTD Direct Evidence: therapeutic CTD PMID:16809570 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEP mRNA, protein:increased expression:brain RGD PMID:20167207 RGD:5509598 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20204486 RGD:2317525 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:17637706 RGD:1643339 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angpt2 angiopoietin 2 IDA RGD PMID:17494864 RGD:2314206 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Anxa1 annexin A1 treatment ISO
IMP
RGD PMID:1830327, PMID:1830327 RGD:7421662, RGD:7421662 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP protein:increased expression:striatum RGD PMID:17640469 RGD:2325742 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:decreased expression:hippocampus CA1, neuron RGD PMID:9030714 RGD:2315686 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) IEP RGD PMID:19616516 RGD:5490152 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:19616516 RGD:5490152 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp5 aquaporin 5 IEP RGD PMID:19616516 RGD:5490152 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Aqp8 aquaporin 8 IEP RGD PMID:19616516 RGD:5490152 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Asic1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:decreased serine phosphorylation:brain RGD PMID:18078455, PMID:22843461 RGD:2292681, RGD:10053716 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19095966 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:15585409 RGD:11522731 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 IEP protein:increased expression:cerebral cortex RGD PMID:17706879, PMID:22843461 RGD:1643491, RGD:10053716 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19922383 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IMP
IEP
protein:increased expression:hippocampus, frontal cortex RGD PMID:19574998, PMID:17936001 RGD:6483094, RGD:6483313 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:11245809 RGD:2289024 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:forebrain RGD PMID:7684483 RGD:2289081 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C3 complement C3 IEP protein:increased expression:brain RGD PMID:14561876 RGD:5129543 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Casp12 caspase 12 IEP mRNA, protein:increased expresssion:brain RGD PMID:12598725 RGD:1299333 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504, PMID:17901229 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 IEP mRNA:increased expression:cerebral cortex RGD PMID:11311984 RGD:2301331 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp9 caspase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin IDA RGD PMID:16467455 RGD:5509813 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17564305, PMID:21213399 RGD:5130891 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 IEP RGD PMID:16417587 RGD:1581152 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15829914, PMID:17394460, PMID:19260320 RGD:2306998 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEP mRNA:increased expression:cerebral cortex RGD PMID:9916893 RGD:69987 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914, PMID:17394460 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:brain (rat) RGD PMID:9670989 RGD:632396 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:20360550 RGD:6893498 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdk5 cyclin-dependent kinase 5 IMP RGD PMID:14502288 RGD:734740 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18501976 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IEP RGD PMID:16434029 RGD:1581188 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Clu clusterin IEP RGD PMID:12782389 RGD:727237 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cp ceruloplasmin IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:18273071 RGD:2314688 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP mRNA,protein:decreased expression,decreased phosphorylation:brain: RGD PMID:23644141 RGD:10059580 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:8541482 RGD:1581300 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta IEP mRNA:increased expression:brain RGD PMID:7643220 RGD:632531 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
JBrowse link
G Csf3 colony stimulating factor 3 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18832793 RGD:2311241 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP RGD PMID:21864831 RGD:5686850 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Cst3 cystatin C ISO protein:decreased expression:cerebrospinal fluid RGD PMID:18261165 RGD:2314349 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:cerebrum (rat) RGD PMID:18404379 RGD:2315571 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsc cathepsin C IEP mRNA:increased expression:cerebral cortex RGD PMID:12843783 RGD:1599640 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsl cathepsin L IEP protein:increased activity:cerebrum (rat) RGD PMID:18404379 RGD:2315571 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:15829914, PMID:17549754 RGD:2311381 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP mRNA, protein:increased expression:brain RGD PMID:18206136 RGD:2306577 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cycs cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dbh dopamine beta-hydroxylase IEP protein:decreased expression:forebrain (rat) RGD PMID:18356740 RGD:5129691 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP Protein:increased expression:brain RGD PMID:15921666 RGD:1599731 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP mRNA:increased expression:brain RGD PMID:19524114 RGD:2316241 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd2 dopamine receptor D2 IEP RGD PMID:11474153 RGD:1580883 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp6 dual specificity phosphatase 6 IEP mRNA:increased expression:brain RGD PMID:10908038 RGD:2316092 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9522364 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Edn1 endothelin 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:8113329 RGD:4144887 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Endog endonuclease G IEP RGD PMID:18568342 RGD:9685367 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Epor erythropoietin receptor IEP protein:increased expression:brain: RGD PMID:14732457 RGD:11041652 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Esr2 estrogen receptor 2 IEP mRNA:decreased expression:cerebral cortex, ipsilateral side (rat) RGD PMID:10414967 RGD:8694344 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:14753426, PMID:15534175 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2r coagulation factor II (thrombin) receptor IEP RGD PMID:14705148 RGD:1302269 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F5 coagulation factor V ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G Fas Fas cell surface death receptor IEP protein:increased expression:brain RGD PMID:16796407 RGD:1600333 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand IEP protein:increased expression:brain RGD PMID:18410517 RGD:2311437 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fga fibrinogen alpha chain treatment IDA RGD PMID:22737923 RGD:11040923 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgf1 fibroblast growth factor 1 IDA
ISO
Rat model using human FGF1 RGD PMID:19497570, PMID:16635575 RGD:5509879, RGD:5509881 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Gal galanin and GMAP prepropeptide IEP RGD PMID:16458372 RGD:1624341 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gc GC, vitamin D binding protein IEP protein:increased expression:urine RGD PMID:11239198 RGD:1625796 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gfra1 GDNF family receptor alpha 1 IEP protein:increased expression:cerebral cortex RGD PMID:10407114 RGD:6218981 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gja1 gap junction protein, alpha 1 IEP protein:increased expression:cerebral cortex RGD PMID:21718970 RGD:6480433 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:decreased activity:brain RGD PMID:7808037 RGD:6484655 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12531513 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO
IDA
IEP
protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:cerebral cortex (rat)
CTD PMID:19429140, PMID:17554006, PMID:18369388, PMID:17101276 RGD:1626331, RGD:9068895, RGD:9068892 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 IEP
IMP
RGD PMID:16464361, PMID:21276833 RGD:1582709, RGD:10755576 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO associated with advanced age and Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15992611 RGD:1626649 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:16805800 RGD:6480229 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 IEP mRNA:increased expression:brain RGD PMID:7629893 RGD:6784525 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460, PMID:19417757 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 IDA
ISO
RGD PMID:16882007, PMID:19332057 RGD:1598411, RGD:2306694 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10rb interleukin 10 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr16:20,370,722...20,383,576
Ensembl chr16:20,371,338...20,383,337
JBrowse link
G Il17a interleukin 17A IEP
ISO
protein, mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain
CTD PMID:15829914, PMID:16305645, PMID:16305645 RGD:4846398, RGD:4846398 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17ra interleukin 17 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il18 interleukin 18 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:15829914, PMID:11807395 RGD:4889510 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236716, PMID:15737438, PMID:15756928, PMID:17394460 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:9236716 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914, PMID:17394460 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer IEP mRNA:increased expression:brain, astrocyte RGD PMID:15469886 RGD:1627568 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:21925238 RGD:7495802 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:21925238 RGD:7495802 NCBI chr 7:135,803,723...135,831,006
Ensembl chr 7:135,803,698...135,832,652
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnk10 potassium two pore domain channel subfamily K member 10 IEP mRNA, protein:increased expression:cerebral cortex, hippocampus (rat) RGD PMID:15652517 RGD:9831167 NCBI chr 6:122,417,079...122,549,532
Ensembl chr 6:122,419,046...122,545,899
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:increased expression:hippocampus (rat) RGD PMID:14741413 RGD:9831127 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18951929 RGD:5684407 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Lgals3 galectin 3 IEP RGD PMID:10931529 RGD:9685227 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lif LIF, interleukin 6 family cytokine IEP mRNA:increased expression:brain RGD PMID:20221422 RGD:2326053 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial IDA RGD PMID:12082077 RGD:633879 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Map2 microtubule-associated protein 2 IEP protein:increased expression:serum RGD PMID:21948028 RGD:6483082 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229, PMID:10536014 RGD:1582169 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229, PMID:15669185 RGD:1582281 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:15797868 RGD:1582325 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapt microtubule-associated protein tau IDA protein:increased phosphorylation RGD PMID:15353210 RGD:1599927 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:6282622 RGD:1582465 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdk midkine ISO RGD PMID:12127679 RGD:1582476 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:31791013 RGD:26884340 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:16112096 RGD:1582554 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP RGD PMID:15963646 RGD:1582577 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:15963646 RGD:1582577 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15060315, PMID:16846501 RGD:1582611 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19417757 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msi1 musashi RNA-binding protein 1 IEP RGD PMID:12205668 RGD:633285 NCBI chr12:46,899,835...46,935,335
Ensembl chr12:46,895,447...46,920,952
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 IEP protein:increased expression:thalamus (rat) RGD PMID:9288726 RGD:2317254 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Nes nestin IEP protein:increased expression:hippocampus RGD PMID:17697621 RGD:1642071 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18628779 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18628779 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos1 nitric oxide synthase 1 IMP
IEP
protein:decreased expression:hippocampus RGD PMID:17451676, PMID:21718970 RGD:1642142, RGD:6480433 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9778187, PMID:17394460 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 IDA
IMP
RGD PMID:21212863, PMID:17600658 RGD:4891961, RGD:2292134 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox4 NADPH oxidase 4 ISO mRNA, protein:increased expression:cerebral cortex (human) RGD PMID:15802177 RGD:1580980 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nppa natriuretic peptide A no_association ISO RGD PMID:11706124 RGD:1626244 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nptxr neuronal pentraxin receptor IEP mRNA:decreased expression:neocortex RGD PMID:12242102 RGD:1642302 NCBI chr 7:121,011,678...121,029,754
Ensembl chr 7:121,011,680...121,029,754
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP protein:decreased expression:brain cortex RGD PMID:17344647 RGD:4892115 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrf1 nuclear respiratory factor 1 IEP mRNA, protein:increase expression:cerebral cortex RGD PMID:18723421 RGD:2302400 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Oprm1 opioid receptor, mu 1 IEP RGD PMID:16176345 RGD:2316630 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IEP protein:increased expression:brain RGD PMID:17997827 RGD:2299171 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen IEP protein:increased expression:brain RGD PMID:12099899 RGD:729592 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pgf placental growth factor ISO RGD PMID:16901914 RGD:6483783 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP mRNA:increased expression:hippocampus RGD PMID:15306117 RGD:1642465 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plat plasminogen activator, tissue type no_association ISO DNA:polymorphism:-7351C>T (human)
CTD Direct Evidence: therapeutic
CTD PMID:7477192, PMID:9259745, PMID:9400355, PMID:9479658, PMID:9566367, PMID:9633741, PMID:10572812, PMID:11108748, PMID:11940547, PMID:12221155, PMID:12511774, PMID:14986460, PMID:15017018, PMID:15087567, PMID:16126134, PMID:16763187, PMID:16809570, PMID:17086147, PMID:17525387, PMID:17903870, PMID:20123226, PMID:20212195, PMID:20488584, PMID:20536612, PMID:21037505, PMID:23876515, PMID:16179568 RGD:1580879 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:9731615, PMID:10472989, PMID:10512912, PMID:17927297 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Ppid peptidylprolyl isomerase D ISO RGD PMID:16103352 RGD:1580699 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP protein:increased expression:cerebral cortex, caudate nucleus (rat) RGD PMID:15713259 RGD:9999408 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEP protein:decreased expression:hippocampus, cerebral cortex, nucleus RGD PMID:12150772 RGD:7327190 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEP protein:decreased expression:hippocampus, cerebral cortex, cytosol, nucleus RGD PMID:12150772 RGD:7327190 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkca protein kinase C, alpha IEP associated with Subarachnoid Hemorrhage;protein:increased phosphorylation:cerebral artery RGD PMID:18032736 RGD:2293301 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:17350602 RGD:1642524 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein ISO RGD PMID:14671240 RGD:1358564 NCBI chr16:81,784,348...81,797,889
Ensembl chr16:81,784,348...81,797,815
JBrowse link
G Ptgis prostaglandin I2 synthase IDA RGD PMID:16094316 RGD:8693629 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage RGD PMID:11740205, PMID:10867793 RGD:5688240, RGD:5688247 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
IDA
protein:increased expression:hippocampus
CTD Direct Evidence: marker/mechanism
CTD PMID:15737438, PMID:17394460, PMID:17564305, PMID:19417757, PMID:21718970, PMID:11158633, PMID:12535784 RGD:6480433, RGD:5688292, RGD:1581286 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IDA protein:increased tyrosine phosphorylation:cerebral cortex RGD PMID:10964954 RGD:1642647 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: therapeutic CTD PMID:18628779 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene IEP protein:increased expression:cerebral cortex RGD PMID:10407114 RGD:6218981 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:serum RGD PMID:21695352 RGD:5508764 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IEP RGD PMID:19471098 RGD:6484225 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Sele selectin E ISO associated with Hypertension
CTD Direct Evidence: marker/mechanism
CTD PMID:17394460, PMID:19107136 RGD:2313600 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:27108052 RGD:11073613 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP protein:increased expression:brain RGD PMID:21325818 RGD:5688411 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc29a1 solute carrier family 29 member 1 IMP RGD PMID:15829178 RGD:2316942 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc6a1 solute carrier family 6 member 1 IMP RGD PMID:15084665 RGD:1643209 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP
IMP
protein:increased expression:brain
mRNA:decreased expression:cerebral cortex (rat)
RGD PMID:17662498, PMID:22036625, PMID:12377375 RGD:1642717, RGD:6771236, RGD:727449 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc8a2 solute carrier family 8 member A2 IEP RGD PMID:16107787 RGD:2316979 NCBI chr 1:78,029,555...78,054,042
Ensembl chr 1:78,025,995...78,060,111
JBrowse link
G Slc8a3 solute carrier family 8 member A3 IEP RGD PMID:16107787 RGD:2316979 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11756504 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15060315, PMID:17901229, PMID:19429140, PMID:10212301 RGD:1625695 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10833313 RGD:1580852 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:15854740 RGD:1581411 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tek TEK receptor tyrosine kinase IEP RGD PMID:11919509 RGD:634324 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP mRNA:increased expression:brain RGD PMID:14997937 RGD:2302105 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased expression:solitary tract nucleus, medulla oblongata, locus coeruleus (rat) RGD PMID:18356740 RGD:5129691 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:brain RGD PMID:19712057 RGD:2325131 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr4 toll-like receptor 4 no_association ISO DNA:polymorphisms: :p.N299G, p.T399I (human) RGD PMID:15258789 RGD:1580737 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15756928 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15829914, PMID:16442237 RGD:1624184 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19095966 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ttr transthyretin IEP RGD PMID:15469881 RGD:1580523 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Ucp2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17052689 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vip vasoactive intestinal peptide IDA RGD PMID:18158987 RGD:5685617 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta IEP protein:increased expression:cerebrospinal fluid RGD PMID:15902199 RGD:2306031 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
brain infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing IDA RGD PMID:19362080 RGD:5686830 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adk adenosine kinase ISO
IMP
RGD PMID:16685255, PMID:9731623 RGD:6482657, RGD:6482667 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adm adrenomedullin treatment ISO RGD PMID:21695352 RGD:5508764 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adnp activity-dependent neuroprotector homeobox IDA RGD PMID:11935065 RGD:1358226 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP
ISO
protein:increased expression:brain subventricular zone (rat)
protein:increased expression:brain white matter (human)
RGD PMID:19053043, PMID:10683518 RGD:2313025, RGD:2313026 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO RGD PMID:17388993 RGD:1601161 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO associated with Metabolic Syndrome X; DNA:polymorphism:g.162A>C rs4769055 (human) RGD PMID:18506375 RGD:2311309 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:22227058 RGD:6483057 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Cfh complement factor H treatment ISO RGD PMID:21695352 RGD:5508764 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Ctsb cathepsin B IEP protein:increased expression:cerebral cortical segment, cytoplasm (rat) RGD PMID:19941836 RGD:2315502 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19417757 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:15485550 RGD:1580908 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:17524524 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gpr17 G protein-coupled receptor 17 ISO CTD Direct Evidence: therapeutic CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Hgf hepatocyte growth factor treatment IDA RGD PMID:16421510 RGD:8548626 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hnmt histamine N-methyltransferase severity IMP RGD PMID:21131122, PMID:16330002 RGD:5509772, RGD:5509773 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:18692933 RGD:2313474 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA, protein:increased expression:brain RGD PMID:7770004 RGD:5509999 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:cerebral cortex (rat) RGD PMID:17678971 RGD:1626644 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mdk midkine IDA RGD PMID:15450683 RGD:1582478 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:brain,blood RGD PMID:31342956 RGD:25824952 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16599837 RGD:1582617 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msi1 musashi RNA-binding protein 1 IEP RGD PMID:15250238 RGD:1582664 NCBI chr12:46,899,835...46,935,335
Ensembl chr12:46,895,447...46,920,952
JBrowse link
G Nes nestin IEP associated with Hypertension RGD PMID:16321245 RGD:1642069 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase IMP associated with Reperfusion Injury RGD PMID:12834903 RGD:2316742 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
JBrowse link
G Pdgfb platelet derived growth factor subunit B IMP RGD PMID:14980813 RGD:1581758 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:16190367 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human) RGD PMID:11798899 RGD:5147807 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22878646 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:14650360 RGD:1601455 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra1 HtrA serine peptidase 1 ISO ClinVar Annotator: match by term: Cerebrovascular disease with thin skin, alopecia, and disc disease
ClinVar Annotator: match by term: CARASIL
ClinVar Annotator: match by term: Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
ClinVar Annotator: match by OMIM:600142
OMIM
ClinVar
PMID:11889251, PMID:18316707, PMID:19387015, PMID:21115960, PMID:21482952, PMID:22900900, PMID:23963851, PMID:24500651, PMID:24535794, PMID:25741868, PMID:25770224, PMID:25772074, PMID:25957642, PMID:26063658, PMID:26467025, PMID:27164673, PMID:32101834, PMID:32581362 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
cerebral infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin disease_progression ISO RGD PMID:28266892 RGD:13702087 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Ace angiotensin I converting enzyme ISO DNA:deletion:intron:IVS16+1464-1751del (human)
ClinVar Annotator: match by term: Stroke, ischemic, susceptibility to
ClinVar PMID:1313972, PMID:1319114, PMID:1328889, PMID:1386652, PMID:1976655, PMID:2847529, PMID:2849100, PMID:7593601, PMID:7729604, PMID:7854377, PMID:7909524, PMID:8131299, PMID:8131300, PMID:8136829, PMID:8170965, PMID:8208911, PMID:8298638, PMID:8314010, PMID:8541160, PMID:8644984, PMID:8675669, PMID:9120002, PMID:9236417, PMID:9259580, PMID:9699903, PMID:9737775, PMID:9916793, PMID:10099885, PMID:10636736, PMID:10643899, PMID:10841123, PMID:11687636, PMID:11956052, PMID:12220450, PMID:12666117, PMID:14657821, PMID:14872014, PMID:15110771, PMID:15277638, PMID:15381116, PMID:15531537, PMID:15534175, PMID:15635071, PMID:19221299, PMID:11596779 RGD:11038922 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adora1 adenosine A1 receptor IDA RGD PMID:17067559 RGD:1625229 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:plasma RGD PMID:23288172 RGD:8696004 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO OMIM NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Ang angiogenin severity ISO protein:increased expression:serum RGD PMID:17823536 RGD:6892714 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Anxa1 annexin A1 treatment IEP associated with Ischemic Attack, Transient RGD PMID:22617647 RGD:7483559 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apoa5 apolipoprotein A5 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :-1131T>C (human) RGD PMID:19107359 RGD:2313314 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apob apolipoprotein B ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism: :3932T>C (human) RGD PMID:17016617 RGD:1601237 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO associated with diabetes mellitus;mRNA:protein:increased expression:blood mononuclear cell: RGD PMID:26717922 RGD:14398486 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332
JBrowse link
G C1r complement C1r ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:23602964 RGD:8552262 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd36 CD36 molecule ISO associated with Hyperlipidemias RGD PMID:22718544 RGD:6893487 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ephx2 epoxide hydrolase 2 IDA RGD PMID:16306811 RGD:1580986 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G F2 coagulation factor II ISO ClinVar Annotator: match by term: Ischemic stroke, susceptibility to OMIM
ClinVar
PMID:2222810, PMID:2429850, PMID:6305407, PMID:8696333, PMID:8896550, PMID:8916933, PMID:9106528, PMID:9292507, PMID:9462220, PMID:9493607, PMID:9531249, PMID:9569177, PMID:9694698, PMID:9869612, PMID:10027711, PMID:10233438, PMID:10233439, PMID:10336270, PMID:10348710, PMID:10348711, PMID:10348712, PMID:10406905, PMID:10477778, PMID:10544935, PMID:11358905, PMID:11443298, PMID:11506076, PMID:11796466, PMID:11874997, PMID:11904676, PMID:15059842, PMID:15534175, PMID:16493002, PMID:19159930, PMID:19289024, PMID:19531787, PMID:19554541, PMID:19560233, PMID:19652888, PMID:20301327, PMID:21243428, PMID:21349849, PMID:23429074, PMID:24033266, PMID:25741868, PMID:27031503, PMID:28492532, PMID:30311386 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F5 coagulation factor V ISO ClinVar Annotator: match by term: Ischemic stroke, susceptibility to OMIM
ClinVar
PMID:7586244, PMID:7803250, PMID:7877648, PMID:7910348, PMID:7911872, PMID:8049422, PMID:8164730, PMID:8164741, PMID:8566967, PMID:8616100, PMID:8822583, PMID:9245936, PMID:9339109, PMID:9372726, PMID:9415695, PMID:9454741, PMID:9459326, PMID:9518910, PMID:9734642, PMID:10328130, PMID:10348711, PMID:10477778, PMID:10494770, PMID:10507841, PMID:10666427, PMID:11018168, PMID:11110695, PMID:11686338, PMID:12070000, PMID:12421138, PMID:14996674, PMID:15534175, PMID:15638861, PMID:16493002, PMID:16931580, PMID:19652888, PMID:20051284, PMID:21116184, PMID:21774968, PMID:23382263, PMID:23900608, PMID:24033266, PMID:25741868, PMID:26251307, PMID:28492532 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F7 coagulation factor VII treatment ISO protein:increased expression, increased activity:plasma (human)
human protein in a mouse model
RGD PMID:14733777, PMID:21998055 RGD:11049518, RGD:11049520 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fbn1 fibrillin 1 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:7611299, PMID:8894692, PMID:9401003, PMID:10533071, PMID:10874320, PMID:11700157, PMID:12402346, PMID:12938084, PMID:14695540, PMID:16220557, PMID:16222657, PMID:16835936, PMID:17253931, PMID:17657824, PMID:17663468, PMID:19159394, PMID:19293843, PMID:21542060, PMID:24033266, PMID:24161884, PMID:25741868, PMID:26133393, PMID:28492532, PMID:30311386 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 severity ISO RGD PMID:23723305 RGD:13792693 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grn granulin precursor ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:18723524, PMID:28492532 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1634355 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:plasma RGD PMID:23288172 RGD:8696004 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:23311871 RGD:10755574 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:20083630 RGD:8547724 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il18 interleukin 18 treatment IEP RGD PMID:20584315 RGD:8655991 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Itga9 integrin subunit alpha 9 susceptibility ISO DNA:SNPs,haplotype:rs189897,rs2212020(human) RGD PMID:21764681 RGD:13602007 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988
JBrowse link
G Lipg lipase G, endothelial type susceptibility ISO DNA:polymorphism: :584C>T (human) RGD PMID:17016617 RGD:1601237 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:14593215 RGD:1580416 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Map2 microtubule-associated protein 2 IDA RGD PMID:22444278 RGD:6483079 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:23968852 RGD:10412642 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Men1 menin 1 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Mir223 microRNA 223 treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir30a microRNA 30a treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir383 microRNA 383 treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr16:57,519,675...57,519,748
Ensembl chr16:57,519,675...57,519,748
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16846501 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16846501 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:10929044 RGD:1580590 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Ischemic stroke, susceptibility to OMIM
ClinVar
PMID:9737779, PMID:9894802, PMID:10475066, PMID:10510054, PMID:10514107, PMID:11026457, PMID:11354626, PMID:11394896, PMID:11745998, PMID:15007011, PMID:16059745, PMID:16813604, PMID:17165044, PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:9388399, PMID:11571335, PMID:12861102, PMID:15827866, PMID:15834039, PMID:18803652, PMID:19180562, PMID:20038773, PMID:20301673, PMID:21616505, PMID:22878905, PMID:25344745, PMID:25741868, PMID:26308724, PMID:26467025, PMID:30311386, PMID:32581362 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Npy neuropeptide Y IEP
ISO
protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:11821007, PMID:17123484 RGD:10448931 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Park7 Parkinsonism associated deglycase treatment ISO RGD PMID:18003894, PMID:18003894 RGD:13462069, RGD:13462069 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO associated with Metabolic Syndrome; DNA:duplication:5' utr:-108 3G>4G (human) RGD PMID:18506375 RGD:2311309 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr11:87,858,323...87,975,549
Ensembl chr11:87,858,453...87,973,422
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO RGD PMID:18201705 RGD:6482775 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:1579960, PMID:1899364, PMID:9183334, PMID:12865603, PMID:15502123, PMID:16148626, PMID:18195371, PMID:18544249, PMID:19473668, PMID:19907167 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:12133459, PMID:15502123, PMID:16773802 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:20138161 RGD:6483804 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human) RGD PMID:10729395 RGD:1580196 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Prkch protein kinase C, eta ISO ClinVar Annotator: match by term: Ischemic stroke
ClinVar Annotator: match by term: Cerebral infarction, susceptibility to
OMIM
ClinVar
PMID:12958323, PMID:17206144, PMID:25741868 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Pros1 protein S ISO DNA:missense mutation:exon:p.R355C (1063C>T) (human) RGD PMID:21172841 RGD:11250416 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Ptgdr prostaglandin D2 receptor IDA associated with Brain Ischemia RGD PMID:19576888 RGD:2316816 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Serpind1 serpin family D member 1 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr11:87,913,814...87,924,880
Ensembl chr11:87,913,806...87,924,816
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:25702149 RGD:11075081 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serping1 serpin family G member 1 treatment ISO associated with Venous Thrombosis RGD PMID:10446335 RGD:8661653 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Slc6a1 solute carrier family 6 member 1 IEP mRNA:increased expression:cerebral cortex, neuron RGD PMID:15349978 RGD:1643205 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Tbxas1 thromboxane A synthase 1 susceptibility ISO DNA:polymorphisms: : RGD PMID:19403042 RGD:11059536 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Thbd thrombomodulin susceptibility ISO DNA:missense mutation:cds:p.A455V (human) RGD PMID:15574195 RGD:5685021 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:16173529 RGD:1580315 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B disease_progression ISO RGD PMID:19895657 RGD:7205492 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO DNA:SNP: :rs2075650 (human) RGD PMID:26171154 RGD:13464126 NCBI chr 1:80,617,749...80,630,253
Ensembl chr 1:80,618,154...80,630,038
JBrowse link
G Tsc2 TSC complex subunit 2 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:30311386 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Vdr vitamin D receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25498546 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vim vimentin IEP RGD PMID:18802758 RGD:6480442 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Zfhx3 zinc finger homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19597491 NCBI chr19:42,753,983...42,925,794
Ensembl chr19:42,758,127...42,920,344
JBrowse link
Chronic Cerebral Hypoperfusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 IEP protein:decreased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:cerebral cortex, synapse RGD PMID:28620701 RGD:13703133 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein IEP protein:increased expression:cerebral white matter: RGD PMID:11743996 RGD:10054250 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Bace1 beta-secretase 1 IEP protein:increased expression:hippocampus RGD PMID:28683457 RGD:13782142 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP mRNA:increased expression:hippocampus RGD PMID:24072673 RGD:10402542 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:21192954 RGD:11541061 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Fth1 ferritin heavy chain 1 IEP protein:increased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Gstp1 glutathione S-transferase pi 1 treatment IDA RGD PMID:16645134 RGD:10401930 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP RGD PMID:24838625 RGD:9686415 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP RGD PMID:24838625 RGD:9686415 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:hippocampus RGD PMID:24072673 RGD:10402542 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:hyperphosphorylation:brain: RGD PMID:24371084 RGD:10412307 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO protein:hyperphosphorylation:corpus callosum, endothelial cell, astrocyte: RGD PMID:24371084 RGD:10412307 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 IEP protein:increased expression:dentate gyrus RGD PMID:17931356 RGD:10412049 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Nos3 nitric oxide synthase 3 IMP RGD PMID:15703700 RGD:13824977 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Tfrc transferrin receptor IEP protein:increased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
Hypoxia-Ischemia, Brain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA RGD PMID:16938277 RGD:2312775 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:22569153 RGD:6903872 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:right cerebral hemisphere (rat) RGD PMID:19447505 RGD:2313021 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:increased expression:nucleus: RGD PMID:12871572, PMID:28108258 RGD:10053564, RGD:13524865 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like IEP protein:increased expression:pineal gland RGD PMID:23336172 RGD:10043348 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21189961, PMID:29635023 RGD:10054502, RGD:13782292 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcan brevican IEP RGD PMID:15817274 RGD:14392799 NCBI chr 2:187,359,674...187,373,133
Ensembl chr 2:187,359,677...187,372,657
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:21189961, PMID:29635023 RGD:10054502, RGD:13782292 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 IDA RGD PMID:24195677 RGD:10053669 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:cerebral cortex
protein:increased expression:brain
RGD PMID:22449108, PMID:25919564 RGD:6483050, RGD:11558017 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEP mRNA,protein:decreased expression:brain: RGD PMID:23236544 RGD:8699519 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Casp1 caspase 1 IEP RGD PMID:23046993 RGD:13782359 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 IDA protein:increased activity:cerebral cortex, hippocampus RGD PMID:18603371 RGD:2311455 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IDA
IEP
protein:increased activity:cerebral cortex, hippocampus RGD PMID:18603371, PMID:23046993, PMID:29635023, PMID:27216999, PMID:21189961 RGD:2311455, RGD:13782359, RGD:13782292, RGD:13782279, RGD:10054502 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:29635023, PMID:23046993 RGD:13782292, RGD:13782359 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEP RGD PMID:23046993 RGD:13782359 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin IEP RGD PMID:10318818 RGD:5683321 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase treatment ISO RGD PMID:21978706 RGD:9068474 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:forebrain (rat) RGD PMID:9270493 RGD:8549543 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IEP mRNA, protein:increased expression:brain RGD PMID:18095591 RGD:4144890
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:cerebral hemisphere (rat) RGD PMID:16516309 RGD:4890442 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 treatment IMP RGD PMID:25665755 RGD:13782373 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Clock clock circadian regulator IEP protein:increased expression:pineal gland RGD PMID:23336172 RGD:10043348 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IEP RGD PMID:19747899 RGD:6483337 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Crp C-reactive protein ISO RGD PMID:20220110 RGD:9585994 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:brain RGD PMID:17549754 RGD:2311381 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:21843499 RGD:9587791 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IEP protein:decreased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Egr1 early growth response 1 IEP mRNA:increased expression:forebrain (rat) RGD PMID:7684483 RGD:2289081 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:8092984 RGD:10395352 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Epha4 Eph receptor A4 IEP protein:increased expression:brain RGD PMID:21736568 RGD:5688765 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Epo erythropoietin treatment IEP
ISO
RGD PMID:24034924, PMID:22156696 RGD:10400911, RGD:10401072 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha IEP mRNA:increased expression:hippocampus RGD PMID:12694393 RGD:632668 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:29635023 RGD:13782292 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:21843499 RGD:9587791 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Foxo3 forkhead box O3 IEP protein:increased expression:cerebral cortex,nucleus: RGD PMID:24229603 RGD:10402203 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Ghr growth hormone receptor IEP protein:increased expression:brain RGD PMID:19524466 RGD:2315620 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP mRNA:decreased expression:hippocampus,cortex: RGD PMID:19892002 RGD:9686395 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hdac3 histone deacetylase 3 IEP protein:decreased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
IDA
protein:increased expression:brain (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:23694759, PMID:18210138, PMID:19595151 RGD:9068873, RGD:9068901 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:25447631 RGD:10766440 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IEP RGD PMID:22526757 RGD:7257595 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Igf1 insulin-like growth factor 1 treatment ISO
IDA
IEP
RGD PMID:11672597, PMID:23694759, PMID:19766709 RGD:8549456, RGD:12904932, RGD:10046049 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO RGD PMID:16787587 RGD:5510005 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IEP RGD PMID:10709766 RGD:10402756 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:brain (rat) RGD PMID:23110519 RGD:7204438 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 severity ISO DNA:polymorphism: :174G>C(human) RGD PMID:22117975 RGD:12792241 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21925238 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21925238 NCBI chr 7:135,803,723...135,831,006
Ensembl chr 7:135,803,698...135,832,652
JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP mRNA:increased expression:brain (rat) RGD PMID:27602087 RGD:12903962 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:21277350 RGD:5684383 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:25919564 RGD:11558017 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2 microtubule-associated protein 2 IDA RGD PMID:21300124 RGD:6483088 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP RGD PMID:21843499 RGD:9587791 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapt microtubule-associated protein tau treatment IDA RGD PMID:25665755 RGD:13782373 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP protein:increased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbp myelin basic protein IEP protein:decreased expression:white matter: RGD PMID:23715956 RGD:7327196 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mmp3 matrix metallopeptidase 3 treatment IEP RGD PMID:21038694 RGD:8694100 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23694759 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP mRNA:increased expression:brain RGD PMID:19633950 RGD:5684358 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP RGD PMID:10215166 RGD:10449494 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Plat plasminogen activator, tissue type onset IEP RGD PMID:18467699 RGD:6483831 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase IDA
IEP
mRNA, protein:increased expression, increased activity:hippocampus (rat) RGD PMID:19587273, PMID:18467699 RGD:2316117, RGD:6483831 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B IEP RGD PMID:23153068 RGD:13515077 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEP STEP33;protein:increased expression:forebrain (rat) RGD PMID:10537057 RGD:9835021 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP RGD PMID:16041802 RGD:9590116 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rnf146 ring finger protein 146 IEP RGD PMID:28108258 RGD:13524865 NCBI chr 1:30,856,923...30,873,814
Ensembl chr 1:30,863,217...30,873,808
JBrowse link
G S100b S100 calcium binding protein B severity ISO associated with Asphyxia Neonatorum;protein:increased expression:urine RGD PMID:14707571 RGD:5508819 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:19587273 RGD:2316117 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP RGD PMID:20883671 RGD:6771331 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Spi1 Spi-1 proto-oncogene IEP protein:increased expression:CA1 field of hippocampus RGD PMID:10713349 RGD:9586724 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Tert telomerase reverse transcriptase treatment IDA RGD PMID:21940960 RGD:11038672 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin treatment ISO RGD PMID:22736466 RGD:7244383 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfam transcription factor A, mitochondrial IEP mRNA:increased expression:cerebral cortex RGD PMID:18723421 RGD:2302400 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28139935 RGD:15090829 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23694759 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
lateral medullary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshb follicle stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17344003 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
middle cerebral artery infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:23149556, PMID:24602692 RGD:12790979, RGD:12791996 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Ace angiotensin I converting enzyme treatment IMP RGD PMID:24471927 RGD:11039026 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 IEP mRNA, protein:increased expression:brain RGD PMID:24090950 RGD:9685436 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23437309 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD PMID:25446913, PMID:24211797 RGD:8696008 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen IEP protein:increased expression:brain, serum RGD PMID:24090950 RGD:9685436 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:altered localization: : RGD PMID:15181376 RGD:10047403 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ak1 adenylate kinase 1 IEP protein:decreased expression:cerebral cortex (rat) RGD PMID:16468349 RGD:5508760 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Alb albumin treatment ISO RGD PMID:22227456 RGD:11036100 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19309543 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:24012531 RGD:13703113 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apoe apolipoprotein E IDA RGD PMID:19623195 RGD:6903926 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein treatment IEP RGD PMID:28963051 RGD:13782054 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp4 aquaporin 4 treatment IEP RGD PMID:20815926 RGD:8695955 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein IEP RGD PMID:22645329 RGD:10395314 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:22200499, PMID:21891976 RGD:10053665, RGD:10053704 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23143152 RGD:10054501 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcan brevican IEP RGD PMID:15869933 RGD:9590118 NCBI chr 2:187,359,674...187,373,133
Ensembl chr 2:187,359,677...187,372,657
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23143152 RGD:10054501 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:20417695 RGD:4891138 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 treatment IMP RGD PMID:22108007 RGD:11561900 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP protein:increased expression:brain RGD PMID:17379825 RGD:9685412 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP RGD PMID:15902200, PMID:21029239 RGD:2314138, RGD:9068917 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G C3 complement C3 IEP
ISO
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD PMID:23199288, PMID:22103620 RGD:7175514 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IEP RGD PMID:14688616 RGD:1358416 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Casp3 caspase 3 treatment IDA
IEP
RGD PMID:21891976, PMID:26868427, PMID:23143152 RGD:10053704, RGD:13782346, RGD:10054501 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 IEP RGD PMID:26868427 RGD:13782346 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:26868427 RGD:13782346 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12374626, PMID:23043544, PMID:25257527 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Cd36 CD36 molecule treatment ISO RGD PMID:25216018 RGD:11041113 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd86 CD86 molecule IEP protein:increased expression:brain subventricular zone, microglial cell (rat) RGD PMID:19053043 RGD:2313025 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO RGD PMID:24920629 RGD:13782375 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cldn5 claudin 5 treatment IEP RGD PMID:24842554 RGD:13204729 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Crh corticotropin releasing hormone IEP protein:decreased expression:median eminence of hypothalamus (rat) RGD PMID:21741032 RGD:5490538 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crp C-reactive protein ISO RGD PMID:15545914 RGD:9585995 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 treatment IEP RGD PMID:20417695 RGD:4891138 NCBI chr16:20,740,746...20,798,145
Ensembl chr16:20,740,826...20,794,039
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO
IEP
mRNA, protein:increased expression:brain: RGD PMID:19298757, PMID:15530654 RGD:11039420, RGD:11039425 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO RGD PMID:10825390 RGD:632989 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:cerebral cortex RGD PMID:10825390 RGD:632989 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP RGD PMID:23002367 RGD:14700877 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:11726790 RGD:9588643 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IMP RGD PMID:23516428 RGD:9589049 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dynll1 dynein light chain LC8-type 1 IEP RGD PMID:9522364 RGD:13208524 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17197033 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:22645329 RGD:10395314 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 IEP RGD PMID:22645329 RGD:10395314 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr4 early growth response 4 IEP RGD PMID:22645329 RGD:10395314 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha treatment IDA
IMP
RGD PMID:23669639, PMID:19763736 RGD:10395346, RGD:10755569 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:10700596 RGD:10450546 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Eng endoglin ISO RGD PMID:24876084 RGD:11041171 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Epcam epithelial cell adhesion molecule IEP RGD PMID:15950761 RGD:11038820 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Epn1 Epsin 1 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr 1:72,294,153...72,310,217
Ensembl chr 1:72,294,153...72,311,856
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:20833153, PMID:20547143 RGD:10400898, RGD:10401066 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IEP RGD PMID:9974119 RGD:10401103 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G F11 coagulation factor XI ISO RGD PMID:16533887 RGD:11041786 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F12 coagulation factor XII treatment ISO RGD PMID:16533887, PMID:16533887 RGD:11041786, RGD:11041786 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2 coagulation factor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:29651748 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP
RGD PMID:18950622, PMID:23378241 RGD:11341807, RGD:11344885 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IDA RGD PMID:25882840 RGD:13792686 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide treatment IDA RGD PMID:19352052 RGD:9850083 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:19352052 RGD:9850083 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 treatment IEP RGD PMID:26674869 RGD:11068571 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grn granulin precursor treatment ISO RGD PMID:23972823 RGD:10401661 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial IEP mRNA:increased expression:cerebral cortex RGD PMID:12505684 RGD:632868 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA RGD PMID:28440874 RGD:13792734 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA, protein:increased expression:cerebral cortex, hippocampus, corpus striatum RGD PMID:21957487 RGD:11041635 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Has2 hyaluronan synthase 2 IEP mRNA:increased expression:brain RGD PMID:11283406 RGD:9588631 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hdac4 histone deacetylase 4 treatment IEP mRNA,protein:decreased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac5 histone deacetylase 5 treatment IEP mRNA,protein:decreased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hdac9 histone deacetylase 9 IEP mRNA:increased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IDA RGD PMID:21029239 RGD:9068917 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:23480850 RGD:9681449 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP
IDA
ISO
RGD PMID:24252362, PMID:23870531, PMID:20888632 RGD:10755587, RGD:10755755, RGD:10755588 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin IEP RGD PMID:22103620 RGD:7175514 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP
ISO
rat gene in mouse model RGD PMID:17473852, PMID:21709150 RGD:5688754, RGD:6218961 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htra2 HtrA serine peptidase 2 IEP
ISO
protein:increased expression:brain, cytosol (rat)
protein:increased expression:brain, cytosol (mouse)
RGD PMID:16978742, PMID:15306124 RGD:2314385, RGD:5688372 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:31250553 RGD:14985213 NCBI chr12:39,822,814...39,851,093
Ensembl chr12:39,822,637...39,850,567
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:16286924 RGD:10045955 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il13 interleukin 13 IEP protein:increased expression:cerebral cortex RGD PMID:23028794 RGD:7204480 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1b interleukin 1 beta treatment IEP
ISO
protein:increased expression:cerebral cortex (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:25257527, PMID:23028794, PMID:29498696, PMID:24916922 RGD:7204480, RGD:13792833, RGD:10450594 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human gene in a rat model RGD PMID:7790404 RGD:8551708 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il22 interleukin 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Il4 interleukin 4 IEP protein:increased expression:cerebral cortex RGD PMID:23028794 RGD:7204480 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 IEP RGD PMID:23028794 RGD:7204480 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:12374626, PMID:21940958, PMID:25257527, PMID:29498696 RGD:13792833 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha IEP protein:decreased expression:brain RGD PMID:29967576 RGD:27226878 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Irf4 interferon regulatory factor 4 IEP RGD PMID:25652434 RGD:11530061 NCBI chr17:34,886,746...34,905,191
Ensembl chr17:34,886,739...34,905,117
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Mag myelin-associated glycoprotein treatment IMP RGD PMID:15678116 RGD:9685232 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:27152455 RGD:13800881 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA RGD PMID:27152455 RGD:13800881 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapt microtubule-associated protein tau treatment IEP
IDA
ISO
RGD PMID:28886009, PMID:25903928, PMID:28886009 RGD:13800886, RGD:13800913, RGD:13800886 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:19309543, PMID:24842554 RGD:13204729 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt3 metallothionein 3 IEP protein:decreased expression:brain RGD PMID:8869568 RGD:9685807 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IEP
IDA
RGD PMID:24583056, PMID:21185267, PMID:23777415 RGD:10040971, RGD:10041016, RGD:10040974 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 IEP RGD PMID:21386696 RGD:13801046 NCBI chr19:653,510...680,378
Ensembl chr19:653,510...680,378
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment IMP RGD PMID:28495827 RGD:13781880 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nefl neurofilament light IEP protein:increased expression:brain RGD PMID:29967576 RGD:27226878 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IDA RGD PMID:23880501, PMID:24466583 RGD:10412696, RGD:10412714 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:21122797 RGD:10413868 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:10408807 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor treatment IDA RGD PMID:22678884 RGD:10413900 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 treatment IEP RGD PMID:24842554 RGD:13204729 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
protein:increased expression:brain (rat)
mRNA:increased expression:brain (mouse)
RGD PMID:21959178, PMID:22020035 RGD:5508751, RGD:5509037 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP protein:increased expression:brain RGD PMID:21120604, PMID:25069640 RGD:5133239, RGD:11035212 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrg1 neuregulin 1 treatment ISO RGD PMID:20691195 RGD:10449015 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase treatment IEP associated with Hypertension RGD PMID:17920569 RGD:8657395 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Park7 Parkinsonism associated deglycase treatment ISO RGD PMID:17882163 RGD:13463450 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment ISO
IDA
IEP
RGD PMID:21311064, PMID:25882840, PMID:23143152, PMID:23801245 RGD:5683909, RGD:13792686, RGD:10054501, RGD:11073732 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment ISO
IEP
protein:increased expression:brain: RGD PMID:16403464, PMID:19352052, PMID:11323519 RGD:9835380, RGD:9850083, RGD:9835381 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment IDA RGD PMID:16917016 RGD:11084934 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment IDA RGD PMID:16917016 RGD:11084934 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plat plasminogen activator, tissue type IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:12297567, PMID:17690543, PMID:18453163, PMID:20547619, PMID:29651748, PMID:14512838 RGD:1580876 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:11677890, PMID:15181847, PMID:17702958 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pld1 phospholipase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Prkcg protein kinase C, gamma ISO RGD PMID:14688616 RGD:1358416 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:24159062 RGD:11100027 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP mRNA:increased expression:cerebral cortex RGD PMID:15869933 RGD:9590118 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Reln reelin severity ISO RGD PMID:16438965 RGD:13207538 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a treatment IEP
IMP
RGD PMID:21840379, PMID:23275173 RGD:9850121, RGD:9850122 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rpl28 ribosomal protein L28 IEP RGD PMID:16805800 RGD:6480229 NCBI chr 1:72,619,282...72,621,941
Ensembl chr 1:72,619,282...72,621,519
JBrowse link
G Runx1 RUNX family transcription factor 1 IAGP mRNA:increased expression:brain RGD PMID:24672479 RGD:11251714 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G S100a5 S100 calcium binding protein A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 2:189,999,669...190,005,877
Ensembl chr 2:190,003,223...190,005,871
JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:14512838 RGD:1580876 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 treatment IDA RGD PMID:22714093 RGD:8655545 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Serpinh1 serpin family H member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Shh sonic hedgehog signaling molecule treatment ISO RGD PMID:22324418 RGD:12879461 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 treatment IMP
ISO
RGD PMID:23600725, PMID:23600725 RGD:9585664, RGD:9585664 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc12a2 solute carrier family 12 member 2 treatment IMP
ISO
protein:increased expression:brain: RGD PMID:12535773, PMID:27798271 RGD:1580583, RGD:14398833 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment IEP RGD PMID:9419067 RGD:12879855 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc9a1 solute carrier family 9 member A1 treatment IMP RGD PMID:31250553 RGD:14985213 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor treatment IEP RGD PMID:14500739 RGD:9999390 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smo smoothened, frizzled class receptor treatment IMP RGD PMID:23696546, PMID:23499832 RGD:12832759, RGD:12879404 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Smox spermine oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30576531 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
G Snap91 synaptosome associated protein 91 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr 8:94,447,558...94,564,772
Ensembl chr 8:94,447,550...94,564,525
JBrowse link
G Sod1 superoxide dismutase 1 treatment IDA
IEP
mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22001340, PMID:22133807 RGD:8657021, RGD:8657023 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sphk2 sphingosine kinase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:23043544 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP RGD PMID:31409163 RGD:14995477 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased expression:substantia nigra pars compacta, neuron (rat) RGD PMID:21366664 RGD:5128609 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor treatment IEP
IMP
RGD PMID:24916922, PMID:15647744, PMID:29498696 RGD:10450594, RGD:13825261, RGD:13792833 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IMP RGD PMID:15647744 RGD:13825261 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Upp1 uridine phosphorylase 1 IEP mRNA, protein:increased expression:brain (rat) RGD PMID:18457515 RGD:2317094 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
Multi-Infarct Dementia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO protein:decreased expression:cerebrospinal fluid: RGD PMID:1677459 RGD:10054257 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:21279683 RGD:10449132 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Il2 interleukin 2 severity ISO protein:increased secretion:mononuclear cell: RGD PMID:8586980 RGD:10047081 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
pyridoxamine 5'-phosphate oxidase deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase ISO ClinVar Annotator: match by term: Pyridoxal phosphate-responsive seizures
ClinVar Annotator: match by term: Pyridoxal 5'-phosphate-dependent epilepsy
ClinVar Annotator: match by OMIM:610090
OMIM
ClinVar
PMID:12200739, PMID:15772097, PMID:18024216, PMID:18485777, PMID:20370816, PMID:21292558, PMID:22858719, PMID:23419474, PMID:24266778, PMID:24645144, PMID:24658933, PMID:24781210, PMID:25256445, PMID:25741868, PMID:25762494, PMID:26467025, PMID:27781031, PMID:28349276, PMID:28492532, PMID:28985901, PMID:30311386 NCBI chr10:84,874,926...84,881,190
Ensembl chr10:84,874,927...84,881,190
JBrowse link
transient cerebral ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 IEP RGD PMID:15781474 RGD:1579751 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP mRNA, protein:increased expression:brain RGD PMID:16630594 RGD:9681747 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 IEP RGD PMID:16630594 RGD:9681747 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 IMP RGD PMID:16504947 RGD:10755337 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23437309 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO
protein:altered expression:cerebral cortex, striatum (rat)
protein:increased expression:brain, plasma
RGD PMID:22528836, PMID:23288172 RGD:7245542, RGD:8696004 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen IEP RGD PMID:21934531 RGD:8549480 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO
mRNA:decreased expression, altered localization:CA1 pyramidal layer, nucleus:
protein:increased expression:nucleus:
RGD PMID:14526224, PMID:15087715 RGD:10047409, RGD:10053562 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ank1 ankyrin 1 IEP RGD PMID:9202331 RGD:1599109 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Ank2 ankyrin 2 IEP RGD PMID:9202331 RGD:1599109 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:19623195 RGD:6903926 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aqp4 aquaporin 4 treatment IEP RGD PMID:24773551 RGD:13207320 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Atf2 activating transcription factor 2 IDA
IEP
RGD PMID:10077326, PMID:9813301 RGD:10047405, RGD:10047413 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP protein:increased expression:cerebrum (rat) RGD PMID:21950801 RGD:13792582 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Bace1 beta-secretase 1 IEP protein:increased activity,increased expression:brain cortex RGD PMID:15120577 RGD:13782170 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bad BCL2-associated agonist of cell death ISO CTD Direct Evidence: marker/mechanism CTD PMID:12629175 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21167243 RGD:10054102 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 IEP protein:increased expression:hippocampus CA1, pyramidal cell RGD PMID:12913114 RGD:634629 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA
protein:decreased expression:brain RGD PMID:18083315, PMID:22509406, PMID:16732092 RGD:2290557, RGD:11561910, RGD:11522725 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l2 Bcl2-like 2 treatment IEP
ISO
protein:increased expression:cortex and caudate putamen RGD PMID:10724126, PMID:12571640 RGD:14394498, RGD:14394500 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bex3 brain expressed X-linked 3 IEP RGD PMID:11124986 RGD:9743974 NCBI chr  X:106,823,442...106,825,016
Ensembl chr  X:106,823,491...106,825,014
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:14972662 RGD:2314028 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G C3 complement C3 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:23199288, PMID:22004711 RGD:7411628 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cab39 calcium binding protein 39 IEP protein:increased expression:brain RGD PMID:27798271 RGD:14398833 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IEP
ISO
protein:increased expression:hippocampus RGD PMID:12951199, PMID:12199152 RGD:7241547, RGD:13681927 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Casp3 caspase 3 IDA RGD PMID:21712070 RGD:10053706 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:25872160 RGD:13782285 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:30148677 RGD:13782286 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEP
ISO
associated with Diabetes Mellitus, Experimental;protein:increased expression:neocortex
CTD Direct Evidence: marker/mechanism
CTD PMID:11333366, PMID:15246841, PMID:21712070 RGD:2311321, RGD:10053706 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cav1 caveolin 1 treatment IEP
ISO
RGD PMID:22007835, PMID:22007835 RGD:8661794, RGD:8661794 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cbl Cbl proto-oncogene treatment IDA RGD PMID:18773943 RGD:4108486 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA
IEP
mRNA:increased expression:brain (rat) RGD PMID:21487414, PMID:7860708 RGD:8549519, RGD:8549729 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IMP RGD PMID:19428685 RGD:7488896 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccnh cyclin H IEP mRNA, protein:increased expression:hippocampus RGD PMID:10501206 RGD:69371 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 IEP mRNA:increased expression:brain RGD PMID:19428685 RGD:7488896 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd40 CD40 molecule severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IEP RGD PMID:28254431 RGD:13506925 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO protein:decreased expression:striatum, neuron RGD PMID:11438580 RGD:8552691 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IEP mRNA, protein:increased expression:hippocampal pyramidal cell layer (rat) RGD PMID:9795105 RGD:10401192 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Chka choline kinase alpha IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:16300643 RGD:10401831 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Coq7 coenzyme Q7, hydroxylase severity ISO RGD PMID:20170652 RGD:10402096 NCBI chr 1:188,176,060...188,190,874
Ensembl chr 1:188,174,874...188,190,860
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IDA RGD PMID:10077326 RGD:10047405 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12437578 RGD:632385 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:12624302 RGD:10450512 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA,protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:hippocampus: RGD PMID:24924806 RGD:11352662 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cycs cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:11333366 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Daxx death-domain associated protein treatment IDA RGD PMID:17967739 RGD:9587802 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dbn1 drebrin 1 IEP RGD PMID:8583659 RGD:10398814 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dffb DNA fragmentation factor subunit beta IEP mRNA, protein:increased expression:hippocampus CA1 RGD PMID:11425895 RGD:628524 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP protein:increased expression:brain RGD PMID:22197701 RGD:7771582 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp16 dual specificity phosphatase 16 IEP protein:increased expression, altered localization:hippocampus, cytosol, nucleus RGD PMID:23280045 RGD:7775014 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Eed embryonic ectoderm development IDA RGD PMID:24007266 RGD:9588303 NCBI chr 1:154,189,252...154,216,340
Ensembl chr 1:154,189,260...154,216,340
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha ISO
IEP
associated with Heart Arrest RGD PMID:11520898, PMID:10541873 RGD:10395353, RGD:11041881 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:19168036 RGD:10450558 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Elk1 ETS transcription factor ELK1 treatment IEP RGD PMID:17091294 RGD:7488902 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP mRNA:increased expression:brain: RGD PMID:9634555 RGD:9685492 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA:increased expression:cerebrum, ipsilateral side (rat) RGD PMID:22196858 RGD:7349341 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epo erythropoietin treatment IEP
ISO
RGD PMID:22282883, PMID:24702327 RGD:10401060, RGD:11041699 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO human gene in a rat model RGD PMID:19440222 RGD:2313668 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:10437118 RGD:10401104 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Esr1 estrogen receptor 1 treatment IDA RGD PMID:24548484, PMID:25098259 RGD:10045843, RGD:10045845 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:23593292 RGD:7364962 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F11r F11 receptor treatment IEP RGD PMID:22868201 RGD:7488943 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F12 coagulation factor XII treatment ISO RGD PMID:16533887, PMID:16533887 RGD:11041786, RGD:11041786 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Fas Fas cell surface death receptor treatment IEP
IDA
ISO
protein:increased expression:brain RGD PMID:18410517, PMID:18981705, PMID:10972965 RGD:2311437, RGD:8686422, RGD:8662928 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP mRNA:increased expression:cerebral cortex: RGD PMID:8858623 RGD:10402044 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 treatment ISO RGD PMID:17077813 RGD:10402150 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmr1 FMRP translational regulator 1 IEP mRNA, protein:increased expression:striatum (rat) RGD PMID:22817682 RGD:11566024 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:22580330 RGD:10449127 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA,protein:decreased expression:brain: RGD PMID:17560544 RGD:12907500 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment ISO
IEP
protein:increased expression:brain RGD PMID:22812228, PMID:23328809 RGD:7207263, RGD:8662426 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb6 gap junction protein, beta 6 IEP protein:increased expression:hippocampus: RGD PMID:21718970 RGD:6480433 NCBI chr15:37,400,888...37,411,656
Ensembl chr15:37,400,889...37,410,848
JBrowse link
G Glrx glutaredoxin IEP mRNA,protein:decreased expression:brain: RGD PMID:10329397 RGD:9686043 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO
IDA
human protein in a rat model RGD PMID:24407245, PMID:21361730, PMID:20145654 RGD:13504852, RGD:13504855, RGD:13504854 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gsr glutathione-disulfide reductase treatment IDA RGD PMID:15525350 RGD:10401855 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:20830300 RGD:8693742 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 treatment IEP RGD PMID:24771108 RGD:9686115 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:cerebral cortex, caudoputamen (rat) RGD PMID:20417628 RGD:9068877 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:brain, plasma RGD PMID:23288172 RGD:8696004 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP protein:altered expression:cerebral cortex, hippocampus (rat) RGD PMID:20421594 RGD:10041006 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B treatment IDA RGD PMID:22366221 RGD:9999181 NCBI chr10:34,955,713...34,961,662
Ensembl chr10:34,955,716...34,961,608
JBrowse link
G Hrh2 histamine receptor H 2 IEP protein:decreased expression:caudate putamen (rat) RGD PMID:16181737 RGD:9685533 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hsf1 heat shock transcription factor 1 treatment IEP
IDA
protein:increased expression:brain, nucleus (rat)
associated with Heart Arrest
RGD PMID:26070787, PMID:23528677 RGD:10402389, RGD:10402772 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:25632565 RGD:11354959 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP protein:increased expression:brain, postsynaptic density (rat) RGD PMID:9425004 RGD:10059344 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP protein:increased expression:brain,astrocyte: RGD PMID:10559386 RGD:10402577 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htra2 HtrA serine peptidase 2 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15306124, PMID:19462455 RGD:10402932 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Htt huntingtin IEP protein:increased degradation:brain RGD PMID:12957494 RGD:1304431 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22379785 RGD:8547729 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP protein:decreased expression:serum (rat) RGD PMID:25098324 RGD:12904924 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP RGD PMID:24261295 RGD:7495766 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:24053818 RGD:7364868 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta IDA
ISO
RGD PMID:23147509, PMID:22284622 RGD:7175551, RGD:7175554 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist IDA
ISO
human protein in a rat model RGD PMID:15837124, PMID:20412072 RGD:1626674, RGD:8551852 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15472100 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Itgb3 integrin subunit beta 3 IEP RGD PMID:18638458 RGD:6907424 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP mRNA:decreased expression:cerebral cortex (rat) RGD PMID:7500836 RGD:6482813 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jak1 Janus kinase 1 IEP RGD PMID:10756075 RGD:19165138 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 IDA RGD PMID:23764464 RGD:8694326 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP protein:decreased expression:CA1 field of hippocampus, astrocyte, astrocyte projection RGD PMID:20833221 RGD:8662899 NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 severity
treatment
ISO
IDA
IEP
protein:increased expression:cerebral cortex (rat) RGD PMID:15175651, PMID:24154701, PMID:25062759 RGD:9831121, RGD:9831178, RGD:9831122 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kdm1a lysine demethylase 1A IEP protein:increased expression:cerebral cortex, hippocampus, dentate gyrus (rat) RGD PMID:20542065 RGD:9588301 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO protein:decreased expression:brain (mouse) RGD PMID:21075092 RGD:6893270 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lmna lamin A/C IDA RGD PMID:17683050 RGD:2293745 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 treatment IDA RGD PMID:17173873 RGD:9850154 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 treatment IEP RGD PMID:11720783 RGD:10412057 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Madd MAP-kinase activating death domain IEP RGD PMID:12625816 RGD:9588641 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA protein:increased threonine phosphorylation:heart, nucleus RGD PMID:9195981 RGD:7495830 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:increased nitrosylation, activity:hippocampus: RGD PMID:23137546 RGD:10412334 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 treatment IDA RGD PMID:18498770, PMID:18382279 RGD:7495845, RGD:7495847 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:70,248,568...70,263,190
Ensembl chr18:70,248,713...70,263,164
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 IEP mRNA:decreased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr 7:12,179,046...12,186,251
Ensembl chr 7:12,179,203...12,186,656
JBrowse link
G Mbp myelin basic protein IEP mRNA:increased expression:oligodendrocyte: RGD PMID:11460777 RGD:7349336 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit IEP mRNA:increased expression:hippocampus RGD PMID:17610559 RGD:11062141 NCBI chr 6:10,887,303...10,899,221
Ensembl chr 6:10,887,288...10,899,200
JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IDA RGD PMID:24334056 RGD:10412310 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Mff mitochondrial fission factor treatment IDA RGD PMID:26116440 RGD:12879457 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mfn2 mitofusin 2 IEP protein:decreased expression:brain (rat) RGD PMID:25147362 RGD:13204807 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir223 microRNA 223 IMP RGD PMID:31237865 RGD:25824937 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IDA
IEP
protein:increased activity, increased expression:brain RGD PMID:11592852, PMID:24828425 RGD:8547930, RGD:8657086 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP
IDA
protein:increased activity, increased expression:brain RGD PMID:16197500, PMID:24773551, PMID:23046750, PMID:11592852 RGD:8547921, RGD:13207320, RGD:13207323, RGD:8547930 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt1 metallothionein 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 IEP mRNA, protein:increased expression:brain RGD PMID:10069533 RGD:9685804 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Myb MYB proto-oncogene, transcription factor IEP mRNA:increased expression:brain: RGD PMID:24828495 RGD:11532683 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment IMP
ISO
RGD PMID:28528966, PMID:25603815 RGD:13781879, RGD:13781895 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ndrg2 NDRG family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23451161 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Ndrg4 NDRG family member 4 ISO RGD PMID:21636852 RGD:7247728 NCBI chr19:9,766,439...9,802,396
Ensembl chr19:9,766,439...9,801,942
JBrowse link
G Nefh neurofilament heavy IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nf1 neurofibromin 1 IEP mRNA,protein:increased expression:astrocyte: RGD PMID:8820972 RGD:12789703 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEP</