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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:ovary epithelial cancer
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Accession:DOID:2152 term browser browse the term
Definition:An ovarian cancer that is derives_from ovarian surface epithelium. (DO)
Synonyms:exact_synonym: epithelial tumor of ovary;   ovarian epithelial cancer;   ovarian surface epithelial-stromal tumor
 primary_id: MESH:C538090
 xref: NCI:C4381
For additional species annotation, visit the Alliance of Genome Resources.

GViewer not supported for the selected species.

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ovary epithelial cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 susceptibility ISO DNA:SNPs: :rs1955513,rs927062(human) RGD PMID:29979793 RGD:14348955 NCBI chrNW_004955409:28,067,814...28,516,881
Ensembl chrNW_004955409:28,077,621...28,516,944 		JBrowse link
G Aspm assembly factor for spindle microtubules ISO protein:altered expression:ovary, cytoplasm RGD PMID:24830737 RGD:13204746 NCBI chrNW_004955406:33,665,675...33,720,468
Ensembl chrNW_004955406:33,661,322...33,720,259 		JBrowse link
G Aurka aurora kinase A disease_progression ISO mRNA, protein:increased expression:ovary RGD PMID:18314619 RGD:2293872 NCBI chrNW_004955445:2,831,073...2,853,151
Ensembl chrNW_004955445:2,831,157...2,853,357 		JBrowse link
G Brd7 bromodomain containing 7 severity ISO mRNA:decreased expression:ovary RGD PMID:24198243 RGD:9586445 NCBI chrNW_004955433:8,425,976...8,462,431
Ensembl chrNW_004955433:8,424,949...8,461,802 		JBrowse link
G Ccnb1 cyclin B1 ISO protein:increased expression:ovary RGD PMID:19608149 RGD:2315936 NCBI chrNW_004955446:140,661...149,500
Ensembl chrNW_004955446:140,093...149,500 		JBrowse link
G Ccng1 cyclin G1 disease_progression ISO protein:increased expression:ovary (human) RGD PMID:25981880 RGD:11055572 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 severity ISO DNA:silent mutation:cds: (rs4987053) (human) RGD PMID:20103664 RGD:6893445 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353 		JBrowse link
G Daxx death domain associated protein ISO RGD PMID:23539629 RGD:9587820 NCBI chrNW_004955437:1,869,692...1,874,041
Ensembl chrNW_004955437:1,869,572...1,873,050 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit disease_progression ISO DNA:snp:3' utr:c.8092C>A (human) RGD PMID:18640939 RGD:13204969 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO DNA:missense mutation:cds:p.D312N (rs1799793) (human) RGD PMID:19786980 RGD:5688741 NCBI chrNW_004955555:2,355,005...2,369,599
Ensembl chrNW_004955555:2,355,005...2,369,599 		JBrowse link
G Fubp1 far upstream element binding protein 1 exacerbates ISO protein:increased expression:epithelium of female gonad (human) RGD PMID:29113212 PMID:30008853 RGD:151361195 RGD:151665180 NCBI chrNW_004955423:15,245,645...15,278,628
Ensembl chrNW_004955423:15,245,610...15,278,628 		JBrowse link
G Htra1 HtrA serine peptidase 1 treatment ISO RGD PMID:16767218 RGD:152977756 NCBI chrNW_004955477:761,127...808,396
Ensembl chrNW_004955477:761,127...808,994 		JBrowse link
G Kif1b kinesin family member 1B susceptibility ISO DNA:snp:intron:c.2537+518A>G (rs17401966) (human) RGD PMID:25854172 RGD:12738465 NCBI chrNW_004955486:3,366,791...3,503,845
Ensembl chrNW_004955486:3,370,596...3,489,052 		JBrowse link
G Plk1 polo like kinase 1 disease_progression ISO protein:increased expression:ovary RGD PMID:14970859 RGD:2299941 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231 		JBrowse link
G Plk3 polo like kinase 3 disease_progression ISO protein:increased expression:ovary RGD PMID:14970859 RGD:2299941 NCBI chrNW_004955464:13,419,562...13,424,104
Ensembl chrNW_004955464:13,419,562...13,424,104 		JBrowse link
G Ptges prostaglandin E synthase ISO protein:increased expression:ovary RGD PMID:17107625 RGD:2300080 NCBI chrNW_004955445:10,053,745...10,056,981 JBrowse link
G Rad51 RAD51 recombinase no_association ISO DNA:polymorphisms: :135G>C, 172G>T RGD PMID:15924337 RGD:2298723 NCBI chrNW_004955416:7,566,715...7,590,628
Ensembl chrNW_004955416:7,566,686...7,590,628 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO mRNA:expression:increased RGD PMID:18937968 RGD:2302556 NCBI chrNW_004955452:4,580,444...4,606,820
Ensembl chrNW_004955452:4,579,331...4,636,884 		JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:stromal cell RGD PMID:10502421 RGD:2300027 NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459 		JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 disease_progression ISO RGD PMID:15269150 RGD:2300386 NCBI chrNW_004955415:6,328,672...6,378,611
Ensembl chrNW_004955415:6,371,059...6,378,529 		JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 ISO mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chrNW_004955437:6,306,151...6,314,332
Ensembl chrNW_004955437:6,306,151...6,314,332 		JBrowse link
G Tab2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 susceptibility ISO DNA:SNP:CDS:rs237028 (human) RGD PMID:31485280 RGD:155663376 NCBI chrNW_004955439:11,826,469...11,903,103
Ensembl chrNW_004955439:11,826,469...11,903,103 		JBrowse link
familiar ovarian carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad51c RAD51 paralog C ISO ClinVar Annotator: match by term: Familial ovarian carcinoma ClinVar PMID:25741868 PMID:33832919 NCBI chrNW_004955451:4,053,195...4,178,226
Ensembl chrNW_004955451:4,145,226...4,178,487 		JBrowse link
Krukenberg carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (IN blood group) ISO protein:increased expression:ovary RGD PMID:16124061 RGD:2289359 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
ovarian carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO DNA:amplification (human) RGD PMID:16721043 RGD:2315603 NCBI chrNW_004955578:950,258...1,004,438
Ensembl chrNW_004955578:967,593...1,004,438 		JBrowse link
G Amh anti-Mullerian hormone treatment ISO RGD PMID:16533786 RGD:2315652 NCBI chrNW_004955495:5,893,375...5,896,152
Ensembl chrNW_004955495:5,893,446...5,895,912 		JBrowse link
G Atad5 ATPase family AAA domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25581431 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:10330348 PMID:10817650 PMID:16461462 PMID:17124347 PMID:23807571 More... NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO protein:increased expression:ovary RGD PMID:15277215 RGD:2289032 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795 		JBrowse link
G Brca1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:7894493 PMID:8808710 PMID:9150154 PMID:10227398 PMID:10389907 More... NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Cabin1 calcineurin binding protein 1 ISO DNA:hypermethylation: : RGD PMID:18757082 RGD:10054392 NCBI chrNW_004955455:8,162,365...8,312,932
Ensembl chrNW_004955455:8,162,315...8,312,909 		JBrowse link
G Camk2n1 calcium/calmodulin dependent protein kinase II inhibitor 1 treatment ISO RGD PMID:26910918 RGD:18337281 NCBI chrNW_004955452:1,044,696...1,046,657
Ensembl chrNW_004955452:1,043,459...1,046,669 		JBrowse link
G Casp6 caspase 6 ISO RGD PMID:17283169 RGD:2301336 NCBI chrNW_004955496:575,839...584,287
Ensembl chrNW_004955496:577,832...584,287 		JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:11032026 PMID:35622184 RGD:2289113 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30365097 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480 		JBrowse link
G Ccnd1 cyclin D1 treatment ISO RGD PMID:18025280 RGD:2296036 NCBI chrNW_004955422:16,449,921...16,462,676
Ensembl chrNW_004955422:16,448,770...16,463,300 		JBrowse link
G Ccne1 cyclin E1 ISO protein:increased expression:ovary RGD PMID:12713563 RGD:2289335 NCBI chrNW_004955468:7,803,610...7,814,872
Ensembl chrNW_004955468:7,803,346...7,814,872 		JBrowse link
G Ccng1 cyclin G1 ISO human cells in mouse model
mRNA:increased expression:ovary (human)		 RGD PMID:26872615 RGD:11555725 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:16199547 PMID:21876083 PMID:24713400 PMID:28492532 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173 		JBrowse link
G Cldn7 claudin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21134740 NCBI chrNW_004955467:9,652,093...9,654,291
Ensembl chrNW_004955467:9,652,093...9,654,291 		JBrowse link
G Dusp1 dual specificity phosphatase 1 disease_progression ISO RGD PMID:12432554 RGD:2298695 NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381 		JBrowse link
G Edn1 endothelin 1 ISO mRNA, protein:increased expression:ovarian tumor (human) RGD PMID:9973223 RGD:4144954 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25115793 NCBI chrNW_004955437:396,736...411,144
Ensembl chrNW_004955437:396,742...411,144 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728 		JBrowse link
G Glra3 glycine receptor alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955403:32,304,178...32,445,135
Ensembl chrNW_004955403:32,304,178...32,445,135 		JBrowse link
G Hdac3 histone deacetylase 3 disease_progression ISO RGD PMID:18714364 RGD:2306205 NCBI chrNW_004955415:12,138,520...12,154,234
Ensembl chrNW_004955415:12,138,870...12,154,234 		JBrowse link
G Il13 interleukin 13 ISO mRNA,protein:increased expression:tumor,ascites:mRNA increased relative to normal ovary, protein increased in tumor tissue/cancer ascites relative to normal ovary/ascites RGD PMID:14984938 RGD:2290344 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Kiss1 KiSS-1 metastasis suppressor disease_progression ISO RGD PMID:18005407 RGD:2302169 NCBI chrNW_004955406:40,043,139...40,045,973
Ensembl chrNW_004955406:40,043,133...40,045,386 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955451:13,365,881...13,398,491
Ensembl chrNW_004955451:13,365,476...13,398,491 		JBrowse link
G L1cam L1 cell adhesion molecule severity ISO protein:increased expression:ovary, serum (human)
human cells, mouse model		 RGD PMID:13678974 PMID:16424028 RGD:6483445 RGD:6483449 NCBI chrNW_004955580:548,442...561,580
Ensembl chrNW_004955580:549,368...561,486 		JBrowse link
G Letmd1 LETM1 domain containing 1 ISO mRNA, protein:increased expression:ovary RGD PMID:12879013 RGD:2314918 NCBI chrNW_004955547:1,574,210...1,586,432
Ensembl chrNW_004955547:1,574,265...1,582,786 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 ISO RGD PMID:12644821 RGD:2306053 NCBI chrNW_004955450:9,181,851...9,205,277
Ensembl chrNW_004955450:9,181,851...9,239,648 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 disease_progression ISO expression inhibits metastatic colonization of secondary sites by cancer cells in the SKOV3ip.1 cell line model system RGD PMID:16489030 RGD:2293338 NCBI chrNW_004955478:3,331,607...3,448,840
Ensembl chrNW_004955478:3,331,607...3,448,842 		JBrowse link
G Mdh2 malate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955456:14,819,406...14,833,547
Ensembl chrNW_004955456:14,819,406...14,837,142 		JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression ISO DNA:polymorphism:promoter RGD PMID:12974393 PMID:19258954 RGD:2306074 RGD:2306083 NCBI chrNW_004955412:6,106,994...6,118,760
Ensembl chrNW_004955412:6,106,994...6,118,760 		JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:18269114 PMID:20028993 PMID:24362816 PMID:25741868 PMID:26467025 More... NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Mtmr14 myotubularin related protein 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30365097 NCBI chrNW_004955561:1,195,689...1,237,852
Ensembl chrNW_004955561:1,195,650...1,237,997 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 ISO mRNA:decreased expression:ovarian carcinoma (human) RGD PMID:16270321 RGD:2317019 NCBI chrNW_004955552:1,867,477...2,040,659
Ensembl chrNW_004955552:1,924,922...2,040,653 		JBrowse link
G Muc16 mucin 16, cell surface associated ISO RGD PMID:20356397 RGD:2325203 NCBI chrNW_004955563:432,160...581,330 JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:11818965 PMID:12606733 PMID:12917422 PMID:15036665 PMID:15635083 More... NCBI chrNW_004955464:12,927,669...12,936,894
Ensembl chrNW_004955464:12,933,497...12,938,468 		JBrowse link
G Nbn nibrin ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:9590180 PMID:16415040 PMID:25741868 PMID:28492532 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 ISO mRNA:increased expression:ovary RGD PMID:11161850 RGD:2293537 NCBI chrNW_004955556:392,412...413,643
Ensembl chrNW_004955556:392,398...412,166 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 severity ISO protein:increased expression:ovary RGD PMID:17533742 RGD:2299164 NCBI chrNW_004955414:14,365,325...14,447,470
Ensembl chrNW_004955414:14,365,157...14,450,611 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:17200671 PMID:20927582 PMID:21165770 PMID:21365267 PMID:25741868 More... NCBI chrNW_004955493:2,149,053...2,175,482
Ensembl chrNW_004955493:2,147,862...2,175,781 		JBrowse link
G Phf21a PHD finger protein 21A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955422:1,857,335...2,045,816
Ensembl chrNW_004955422:1,857,335...2,045,816 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:30365097 NCBI chrNW_004955496:6,934,542...7,059,745
Ensembl chrNW_004955496:6,908,224...7,059,816 		JBrowse link
G Prkca protein kinase C alpha severity ISO RGD PMID:12888898 RGD:2292460 NCBI chrNW_004955478:5,686,639...6,090,356
Ensembl chrNW_004955478:5,686,640...6,083,967 		JBrowse link
G Prkci protein kinase C iota disease_progression ISO RGD PMID:12888898 RGD:2292460 NCBI chrNW_004955420:423,406...486,676
Ensembl chrNW_004955420:423,140...489,592 		JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO protein:increased tyrosine phosphorylation:ovary
protein:increased expression:ovary		 RGD PMID:10526262 PMID:15455382 RGD:2292563 RGD:2292572 NCBI chrNW_004955461:14,337,914...14,622,779
Ensembl chrNW_004955461:14,337,914...14,556,931 		JBrowse link
G Rad51d RAD51 paralog D ISO ClinVar Annotator: match by term: Ovarian carcinoma ClinVar PMID:16199547 PMID:21822267 PMID:25741868 PMID:26720727 PMID:26720728 More... NCBI chrNW_004955481:9,795,102...9,810,426
Ensembl chrNW_004955481:9,795,102...9,810,426 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955429:17,980,956...18,049,723
Ensembl chrNW_004955429:18,025,932...18,049,723 		JBrowse link
G Rhoa ras homolog family member A disease_progression ISO mRNA, protein:increased expression:ovary RGD PMID:12808121 RGD:2298873 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
G Rhoc ras homolog family member C ISO mRNA:increased expression:ovary RGD PMID:12808121 RGD:2298873 NCBI chrNW_004955435:16,115,095...16,117,736
Ensembl chrNW_004955435:16,115,095...16,117,869 		JBrowse link
G Rspo1 R-spondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25581431 NCBI chrNW_004955452:15,415,417...15,435,616
Ensembl chrNW_004955452:15,415,932...15,435,656 		JBrowse link
G Six1 SIX homeobox 1 severity ISO mRNA:increased expression:female gonad (human) RGD PMID:17409410 RGD:11561962 NCBI chrNW_004955466:8,961,597...8,966,069
Ensembl chrNW_004955466:8,961,597...8,966,069 		JBrowse link
G Smad2 SMAD family member 2 ISO RGD PMID:14985451 RGD:2299967 NCBI chrNW_004955402:33,131,760...33,217,144
Ensembl chrNW_004955402:33,136,778...33,216,844 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO DNA:hypermethylation RGD PMID:15361843 RGD:2298907 NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO DNA:hypermethylation RGD PMID:15361843 RGD:2298907 NCBI chrNW_004955405:30,349,956...30,623,849
Ensembl chrNW_004955405:30,366,866...30,375,468
Ensembl chrNW_004955405:30,366,866...30,375,468 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30365097 NCBI chrNW_004955451:13,567,377...13,595,685
Ensembl chrNW_004955451:13,567,377...13,595,685 		JBrowse link
G Stk11 serine/threonine kinase 11 susceptibility ISO DNA:loss of heterozygosity, missense mutation:p.P281L RGD PMID:10429654 RGD:2298556 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
G Stn1 STN1 subunit of CST complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:28346442 NCBI chrNW_004955485:6,748,682...6,784,119
Ensembl chrNW_004955485:6,748,234...6,784,762 		JBrowse link
G Synpo2 synaptopodin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25581431 NCBI chrNW_004955428:21,152,210...21,323,254
Ensembl chrNW_004955428:21,154,277...21,360,960 		JBrowse link
G Tff1 trefoil factor 1 ISO RGD PMID:9066601 RGD:2292004 NCBI chrNW_004955407:39,363,693...39,365,724 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 disease_progression ISO protein:increased expression:ovary RGD PMID:17009974 RGD:2290414 NCBI chrNW_004955429:14,689,016...14,693,211
Ensembl chrNW_004955429:14,685,031...14,693,211 		JBrowse link
G Tmt1b thiol methyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955458:3,319,840...3,322,777
Ensembl chrNW_004955458:3,319,840...3,322,777 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25535366 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Usp32 ubiquitin specific peptidase 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28811376 NCBI chrNW_004955451:1,511,687...1,678,546 JBrowse link
G Vegfd vascular endothelial growth factor D disease_progression ISO RGD PMID:18343598 RGD:2315478 NCBI chrNW_004955519:2,813,475...2,845,856
Ensembl chrNW_004955519:2,813,438...2,845,915 		JBrowse link
G Wnt4 Wnt family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25581431 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
ovarian clear cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A treatment ISO human cell in mouse model RGD PMID:21900401 RGD:126725086 NCBI chrNW_004955452:6,068,631...6,120,759
Ensembl chrNW_004955452:6,068,631...6,120,759 		JBrowse link
ovarian endometrial cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef10l Rho guanine nucleotide exchange factor 10 like susceptibility ISO DNA:SNP: :rs2256787(human) RGD PMID:29979793 RGD:14348955 NCBI chrNW_004955527:1,315,509...1,448,306
Ensembl chrNW_004955527:1,314,077...1,448,366 		JBrowse link
ovarian serous carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef10l Rho guanine nucleotide exchange factor 10 like susceptibility ISO DNA:SNP:intron:rs10788679(human) RGD PMID:29979793 RGD:14348955 NCBI chrNW_004955527:1,315,509...1,448,306
Ensembl chrNW_004955527:1,314,077...1,448,366 		JBrowse link
G Ccng1 cyclin G1 severity ISO mRNA, protein:increased expression:ovary (human) RGD PMID:30565428 RGD:151361205 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 ISO ovarian serous carcinoma; DNA:loss of heterozygosity:tumor:24/28 (86%) of high-grade tumors, also decreased expression in 96/128 (75%) of tumors RGD PMID:16627982 RGD:2293332 NCBI chrNW_004955467:5,188,036...5,295,570
Ensembl chrNW_004955467:5,187,356...5,307,692 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:25455994 RGD:40907066 NCBI chrNW_004955412:14,630,109...14,923,847
Ensembl chrNW_004955412:14,630,443...14,923,926 		JBrowse link
G Pten phosphatase and tensin homolog exacerbates ISO protein:increased expression:ovary, peritoneum (human) RGD PMID:26166715 RGD:11532228 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Wt1 WT1 transcription factor ISO RGD PMID:19856421 RGD:2315539 NCBI chrNW_004955476:10,464,688...10,504,473
Ensembl chrNW_004955476:10,464,616...10,504,473 		JBrowse link
ovarian serous cystadenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:26619011 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Birc3 baculoviral IAP repeat containing 3 exacerbates ISO mRNA:increased expression:ovary (human) RGD PMID:31964418 RGD:153344516 NCBI chrNW_004955412:5,624,865...5,643,520
Ensembl chrNW_004955412:5,628,973...5,643,410 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:24033266 PMID:24446311 PMID:25157968 PMID:25741868 PMID:26619011 More... NCBI chrNW_004955494:2,567,238...2,712,708 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:22908275 PMID:26619011 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chrNW_004955471:6,852,459...7,026,590
Ensembl chrNW_004955471:6,848,101...6,955,881 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004955476:11,493,299...11,507,022
Ensembl chrNW_004955476:11,491,688...11,506,700 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chrNW_004955435:18,001,517...18,009,105
Ensembl chrNW_004955435:18,001,517...18,009,103 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit Aalpha ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More... NCBI chrNW_004955558:381,794...410,485
Ensembl chrNW_004955558:381,794...410,485 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Ovarian serous cystadenocarcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
ovarian small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO ClinVar Annotator: match by term: Small cell carcinoma of the ovary, hypercalcemic type ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chrNW_004955495:2,021,671...2,105,155
Ensembl chrNW_004955495:2,021,566...2,105,397 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Small cell carcinoma of the ovary, hypercalcemic type ClinVar NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
ovary adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd3 cyclin D3 disease_progression ISO RGD PMID:17885491 RGD:2316011 NCBI chrNW_004955437:8,266,523...8,273,855
Ensembl chrNW_004955437:8,268,118...8,273,855 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Ovarian adenocarcinoma ClinVar PMID:15457249 PMID:18339846 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G LOC102013768 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial ISO mRNA:increased expression:ovary (human) RGD PMID:16180015 RGD:151361183 NCBI chrNW_004955445:4,874,583...4,891,723
Ensembl chrNW_004955445:4,873,942...4,891,780 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator severity ISO mRNA, protein:increased expression:female gonad (human) RGD PMID:18709641 RGD:11535054 NCBI chrNW_004955455:6,921,420...6,930,453
Ensembl chrNW_004955455:6,921,052...6,930,537 		JBrowse link
ovary serous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A ISO ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary ClinVar NCBI chrNW_004955452:6,068,631...6,120,759
Ensembl chrNW_004955452:6,068,631...6,120,759 		JBrowse link
G Brca1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma ClinVar PMID:16084575 PMID:16455195 PMID:16949048 PMID:17100994 PMID:19656164 More... NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Brca2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Ovarian serous surface papillary adenocarcinoma ClinVar PMID:16793542 PMID:18704680 PMID:25741868 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432 		JBrowse link
G Bsg basigin (Ok blood group) ISO protein:increased expression:ovary RGD PMID:16633062 RGD:2289053 NCBI chrNW_004955495:7,148,806...7,156,296 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Primary low grade serous adenocarcinoma of ovary ClinVar PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 More... NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758 		JBrowse link
G Tp53 tumor protein p53 ISO DNA, protein:loss of heterozygosity, increased expression:ovary RGD PMID:1310251 RGD:2290540 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16063
    disease of cellular proliferation 6683
      Neoplasms by Histologic Type 4638
        Glandular and Epithelial Neoplasms 3244
          ovary epithelial cancer 112
            Krukenberg carcinoma 1
            malignant ovarian surface epithelial-stromal neoplasm + 90
            ovarian endometrial cancer 1
            ovarian mucinous neoplasm + 0
            ovarian papillary neoplasm + 0
            ovary transitional cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 16063
    disease of anatomical entity 13820
      Urogenital Diseases 4394
        Female Urogenital Diseases and Pregnancy Complications 2183
          Female Urogenital Diseases 1803
            female reproductive system disease 1800
              Adnexal Diseases 848
                ovarian disease 841
                  Ovarian Neoplasms 541
                    ovarian cancer 423
                      ovary epithelial cancer 112
                        Krukenberg carcinoma 1
                        malignant ovarian surface epithelial-stromal neoplasm + 90
                        ovarian endometrial cancer 1
                        ovarian mucinous neoplasm + 0
                        ovarian papillary neoplasm + 0
                        ovary transitional cell carcinoma 0
paths to the root