Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:anxiety disorder
go back to main search page
Accession:DOID:2030 term browser browse the term
Definition:A cognitive disorder that involves an excessive, irrational dread of everyday situations. (DO)
Synonyms:exact_synonym: ANXIETY;   Neurotic Anxiety State;   anxiety disorders;   anxiety neuroses;   anxiety state;   neurotic anxiety states
 narrow_synonym: HARM AVOIDANCE
 related_synonym: SEROTONIN TRANSPORTER ACTIVITY, INCREASED/DECREASED
 primary_id: MESH:D001008
 alt_id: OMIM:607834
 xref: ICD10CM:F41.9;   NCI:C2878
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:25741868 NCBI chr 7:42,762,021...42,785,192
Ensembl chr 7:42,748,136...42,782,999
JBrowse link
G ADORA2A adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 PMID:16118787 PMID:18305461 PMID:20532872 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:21669254 RGD:6480479 NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684
JBrowse link
G APP amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19664757 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G AVPR1B arginine vasopressin receptor 1B treatment ISO RGD PMID:21956463 PMID:24654684 RGD:14700666 RGD:14700676 NCBI chr38:2,440,574...2,446,037
Ensembl chr38:2,440,615...2,446,037
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429
JBrowse link
G CARTPT CART prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12600694 NCBI chr 2:54,865,043...54,867,410
Ensembl chr 2:54,865,298...54,867,158
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO associated with Sciatic Neuropathy; RGD PMID:24907405 RGD:8661781 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19220484 PMID:29944862 NCBI chr13:38,343,966...38,355,534
Ensembl chr13:38,346,104...38,355,468
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23419392 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722
JBrowse link
G CNR1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15081793 PMID:18690112 NCBI chr12:47,537,240...47,560,723
Ensembl chr12:47,509,583...47,560,983
JBrowse link
G CRH corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:7816204 PMID:8736133 PMID:11440811 PMID:11875628 PMID:12424556 PMID:12438692 PMID:14575894 PMID:16495007 PMID:17293045 PMID:21268831 PMID:22231481 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9299637 PMID:22231481 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10742108 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142
JBrowse link
G CRP C-reactive protein ISO CTD Direct Evidence: marker/mechanism
associated with Coronary Disease;
CTD
RGD
PMID:18603621 PMID:20194079 RGD:9491832 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
G CTNND2 catenin delta 2 susceptibility ISO DNA:polymorphism:multiple (human) RGD PMID:24256404 RGD:40902831 NCBI chr34:2,521,730...3,438,218
Ensembl chr34:2,521,724...3,437,292
JBrowse link
G DISC1 DISC1 scaffold protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29643356 NCBI chr 4:7,524,336...7,825,143
Ensembl chr 4:7,524,397...7,822,558
JBrowse link
G DIXDC1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chr 5:21,097,000...21,168,470
Ensembl chr 5:21,100,045...21,167,166
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23791455 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA:decreased expression:hypothalamus: RGD PMID:23529784 RGD:9588317 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G DRD2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism
DNA:snp:cds:p.H313H (human)
CTD
RGD
PMID:9513185 PMID:18305461 PMID:20532872 RGD:1358603 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G EOMES eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26415720 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527
JBrowse link
G ESR2 estrogen receptor 2 treatment ISO RGD PMID:24015243 PMID:24631553 RGD:10045678 RGD:7364908 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691
JBrowse link
G FMR1 FMRP translational regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28616095 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16488545 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467
JBrowse link
G GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18313124 NCBI chr13:42,367,988...42,488,069
Ensembl chr13:42,368,949...42,488,075
JBrowse link
G GAD1 glutamate decarboxylase 1 susceptibility ISO DNA:snp(s) RGD PMID:22328461 RGD:6480264 NCBI chr36:15,351,289...15,391,701
Ensembl chr36:15,349,683...15,391,824
JBrowse link
G GLO1 glyoxalase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr12:7,584,141...7,609,615
Ensembl chr12:7,585,531...7,609,550
JBrowse link
G GNB1 G protein subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295
JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17434465 NCBI chr14:8,982,180...9,719,813
Ensembl chr14:8,983,802...9,719,357
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chr 4:64,777,069...65,162,603
Ensembl chr 4:64,775,577...65,160,444
JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:23485013 RGD:9590265 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578
JBrowse link
G HMBS hydroxymethylbilane synthase ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:25741868 NCBI chr 5:14,767,306...14,775,205
Ensembl chr 5:14,767,666...14,775,082
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO RGD PMID:21512427 RGD:5683629 NCBI chr 2:50,005,277...50,006,548
Ensembl chr 2:50,002,740...50,006,548
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ISO RGD PMID:12040062 RGD:625756 NCBI chr12:38,659,088...38,659,546 JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO RGD PMID:17074317 RGD:1625000 NCBI chr  X:87,342,800...87,641,224
Ensembl chr  X:87,342,792...87,638,579
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16828124 PMID:21859099 RGD:6482189 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191
JBrowse link
G KDM3B lysine demethylase 3B ISO RGD PMID:24397026 RGD:9590119 NCBI chr11:25,954,352...26,024,919
Ensembl chr11:25,943,864...26,023,866
JBrowse link
G L1CAM L1 cell adhesion molecule ISO protein:increased expression: brain, multiple (rat) RGD PMID:19746433 RGD:6483075 NCBI chr  X:121,708,695...121,722,819
Ensembl chr  X:121,708,894...121,733,365
JBrowse link
G LOC491316 midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:19217924 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25653350 NCBI chr18:17,973,058...19,098,785
Ensembl chr18:17,918,928...18,930,059
JBrowse link
G MAPT microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:29860433 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22231481 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20177408
G MIR34A microRNA mir-34a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27424985 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897
JBrowse link
G NCOR1 nuclear receptor corepressor 1 ISO RGD PMID:20051490 RGD:5688287 NCBI chr 5:39,687,530...39,837,003
Ensembl chr 5:39,687,543...39,836,464
JBrowse link
G NPS neuropeptide S ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:19339610 PMID:21466221 NCBI chr28:36,488,430...36,492,524
Ensembl chr28:36,488,500...36,492,090
JBrowse link
G NPY neuropeptide Y susceptibility ISO DNA:SNPs, haplotypes
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:11440811 PMID:22328461 RGD:6480264 NCBI chr14:37,824,579...37,831,289
Ensembl chr14:37,823,861...37,831,443
JBrowse link
G NPY1R neuropeptide Y receptor Y1 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:11440811 PMID:21803058 RGD:10448284 NCBI chr15:59,580,546...59,587,753
Ensembl chr15:59,580,809...59,583,237
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19228979 NCBI chr24:18,193,381...18,194,232
Ensembl chr24:18,193,339...18,194,170
JBrowse link
G PAM peptidylglycine alpha-amidating monooxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19815072 NCBI chr 3:8,141,508...8,312,081
Ensembl chr 3:8,142,061...8,290,477
JBrowse link
G RAI1 retinoic acid induced 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18285828 NCBI chr 5:41,687,436...41,797,354
Ensembl chr 5:41,688,479...41,808,918
JBrowse link
G SERPINA1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659342 NCBI chr 8:63,388,498...63,400,377
Ensembl chr 8:63,376,945...63,398,435
JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18272690 NCBI chr 1:106,086,094...106,128,700
Ensembl chr 1:106,097,048...106,114,673
JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19120712 NCBI chr34:11,209,118...11,245,456
Ensembl chr34:11,210,939...11,246,742
JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO OMIM NCBI chr 9:44,224,026...44,259,655
Ensembl chr 9:44,224,229...44,259,736
JBrowse link
G TAFA2 TAFA chemokine like family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29339520 NCBI chr10:4,998,538...5,134,970
Ensembl chr10:4,999,695...5,233,553
JBrowse link
G TG thyroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30373627 NCBI chr13:29,350,726...29,597,908
Ensembl chr13:29,350,688...29,598,040
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20194079 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G UCN urocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16488545 NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312
JBrowse link
G USH2A usherin ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:9624053 PMID:10090909 PMID:10729113 PMID:10909849 PMID:11402400 PMID:12112664 PMID:12525556 PMID:14970843 PMID:15025721 PMID:15325563 PMID:15326663 PMID:17405132 PMID:18641288 PMID:19881469 PMID:20145675 PMID:20301515 PMID:20507924 PMID:22581970 PMID:24033266 PMID:24088041 PMID:24160897 PMID:24607488 PMID:24944099 PMID:25097241 PMID:25404053 PMID:25649381 PMID:25741868 PMID:26633545 PMID:26872967 PMID:28041643 PMID:28492532 PMID:29953849 PMID:30718709 NCBI chr38:11,063,221...11,750,444
Ensembl chr38:11,063,817...11,750,444
JBrowse link
acute stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:20645790 RGD:5509849 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429
JBrowse link
G CRP C-reactive protein ISO RGD PMID:19628221 RGD:9585647 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
dopamine beta-hydroxylase deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO OMIM NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:21209083 RGD:5685690 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
generalized anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 severity ISO protein:increased expression:serum (human) RGD PMID:27512921 RGD:39938860 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051
JBrowse link
G SLC6A4 solute carrier family 6 member 4 treatment ISO DNA:repeats, haplotype:promoter: RGD PMID:22907732 RGD:36947386 NCBI chr 9:44,224,026...44,259,655
Ensembl chr 9:44,224,229...44,259,736
JBrowse link
neurocirculatory asthenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC6A2 solute carrier family 6 member 2 ISO orthostatic intolerance,OMIM:604715;DNA:point mutation:exon:A457P RGD PMID:10684912 RGD:1624278 NCBI chr 2:60,319,304...60,362,532
Ensembl chr 2:60,318,999...60,363,120
JBrowse link
obsessive-compulsive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:12836135 RGD:734644 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G CCKBR cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8878350 NCBI chr21:29,602,066...29,606,343
Ensembl chr21:29,604,150...29,605,725
JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:11840516 RGD:1300383 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G HOXB8 homeobox B8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11779477 NCBI chr 9:24,874,893...24,888,981
Ensembl chr 9:24,874,899...24,877,504
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:tandem repeat polymorphism:3' end: RGD PMID:8832771 RGD:12738360 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G HTR1D 5-hydroxytryptamine receptor 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:10621951 NCBI chr 2:76,198,343...76,200,005 JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO OMIM NCBI chr22:4,453,715...4,510,934
Ensembl chr22:4,453,715...4,511,037
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:17267119 RGD:6482188 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191
JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO OMIM NCBI chr 9:44,224,026...44,259,655
Ensembl chr 9:44,224,229...44,259,736
JBrowse link
G SLITRK5 SLIT and NTRK like family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20418887 NCBI chr22:39,381,201...39,390,728
Ensembl chr22:39,384,666...39,387,542
JBrowse link
Orthostatic Hypotension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12082591 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G GNAS GNAS complex locus sussceptibility ISO DNA:SNP: : 393T>C(human) RGD PMID:11910300 RGD:1580406 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G GNB3 G protein subunit beta 3 susceptibility ISO DNA:SNP: : 825C>T (human) RGD PMID:11910300 RGD:1580406 NCBI chr27:38,175,928...38,182,473
Ensembl chr27:38,175,931...38,181,763
JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 ISO RGD PMID:10449650 RGD:1581056 NCBI chr MT:3,914...4,955
Ensembl chr MT:3,914...4,957
JBrowse link
G OPRD1 opioid receptor delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2981652 NCBI chr 2:71,685,129...71,721,692
Ensembl chr 2:71,689,084...71,721,875
JBrowse link
G OPRM1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2981652 NCBI chr 1:43,972,915...44,037,477
Ensembl chr 1:43,972,219...44,141,238
JBrowse link
Orthostatic Hypotension 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYB561 cytochrome b561 ISO OMIM NCBI chr 9:11,461,738...11,474,413
Ensembl chr 9:11,463,585...11,468,282
JBrowse link
Orthostatic Intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC6A2 solute carrier family 6 member 2 ISO OMIM NCBI chr 2:60,319,304...60,362,532
Ensembl chr 2:60,318,999...60,363,120
JBrowse link
panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684
JBrowse link
G CCKBR cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:8878350 PMID:15354400 RGD:1358454 NCBI chr21:29,602,066...29,606,343
Ensembl chr21:29,604,150...29,605,725
JBrowse link
G COMT catechol-O-methyltransferase ISO OMIM NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:14675801 RGD:1358525 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO RGD PMID:20817074 PMID:21421022 RGD:5683630 RGD:5683631 NCBI chr 2:50,005,277...50,006,548
Ensembl chr 2:50,002,740...50,006,548
JBrowse link
G INS insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122
JBrowse link
G LOC479260 mannose-binding protein A susceptibility ISO DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MAOA monoamine oxidase A ISO RGD PMID:15670397 RGD:1600723 NCBI chr  X:37,678,933...37,744,757
Ensembl chr  X:37,677,493...37,744,757
JBrowse link
G TPH2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chr10:13,442,611...13,526,537
Ensembl chr10:13,442,611...13,527,243
JBrowse link
phobic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15309392 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:tandem repeat polymorphism:3' end: RGD PMID:8832771 RGD:12738360 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G MED12 mediator complex subunit 12 ISO DNA:mutation:multiple RGD PMID:12216017 RGD:1358728 NCBI chr  X:55,487,629...55,508,941
Ensembl chr  X:55,482,013...55,509,992
JBrowse link
G PRL prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2554359 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824
JBrowse link
post-traumatic stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BDNF brain derived neurotrophic factor susceptibility ISO DNA:missense mutation:cds:196G>A (p.V66M) (human) RGD PMID:23319005 RGD:10059367 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G CASP12 caspase 12 ISO RGD PMID:25331812 RGD:13782181 NCBI chr 5:27,162,840...27,176,964
Ensembl chr 5:27,161,700...27,177,683
JBrowse link
G CASP9 caspase 9 ISO RGD PMID:25331812 RGD:13782181 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:25331812 RGD:13782181 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:21714072 RGD:5147887 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:23174211 RGD:10412309 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO mRNA, protein:altered expression:locus coeruleus (rat) RGD PMID:21584742 RGD:5686336 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO protein:increased expression:hippocampus RGD PMID:20863519 RGD:5684783 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO RGD PMID:25331812 RGD:13782181 NCBI chr30:10,487,926...10,513,437
Ensembl chr30:10,487,921...10,513,397
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein treatment ISO RGD PMID:17968352 RGD:8694407 NCBI chr13:38,451,722...38,466,481
Ensembl chr13:38,451,710...38,475,827
JBrowse link
separation anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD4 dopamine receptor D4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20731709
social phobia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNTNAP2 contactin associated protein 2 susceptibility ISO DNA:SNP: :rs2710102(human) RGD PMID:21193173 RGD:13450911 NCBI chr16:2,239,953...4,208,718
Ensembl chr16:2,243,918...4,208,416
JBrowse link
Vasovagal Syncope term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPB natriuretic peptide B ISO associated with Syncope;protein:increased expression:serum: RGD PMID:23373852 RGD:7247623 NCBI chr 2:84,395,844...84,397,473 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13742
    disease of anatomical entity 13397
      nervous system disease 11148
        central nervous system disease 9743
          brain disease 9152
            disease of mental health 6717
              cognitive disorder 1759
                anxiety disorder 101
                  Neuroticism 0
                  acute stress disorder + 15
                  generalized anxiety disorder 2
                  neurocirculatory asthenia + 11
                  neurotic disorder 0
                  obsessive-compulsive disorder + 10
                  panic disorder + 10
                  phobic disorder + 5
                  post-traumatic stress disorder 12
                  separation anxiety disorder 1
paths to the root