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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:anxiety disorder
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Accession:DOID:2030 term browser browse the term
Definition:A cognitive disorder that involves an excessive, irrational dread of everyday situations. (DO)
Synonyms:exact_synonym: ANXIETY;   Neurotic Anxiety State;   anxiety disorders;   anxiety neuroses;   anxiety state;   neurotic anxiety states
 narrow_synonym: HARM AVOIDANCE
 related_synonym: SEROTONIN TRANSPORTER ACTIVITY, INCREASED/DECREASED
 primary_id: MESH:D001008
 alt_id: OMIM:607834
 xref: ICD10CM:F41.9;   NCI:C2878
For additional species annotation, visit the Alliance of Genome Resources.


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anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase RNA specific ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:25741868 NCBI chrNW_004955545:1,078,319...1,106,938
Ensembl chrNW_004955545:1,078,319...1,106,938
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 PMID:16118787 PMID:18305461 PMID:20532872 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505
JBrowse link
G Adra2a adrenoceptor alpha 2A ISO RGD PMID:21669254 RGD:6480479 NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
JBrowse link
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19664757 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Avpr1b arginine vasopressin receptor 1B treatment ISO RGD PMID:21956463 PMID:24654684 RGD:14700666 RGD:14700676 NCBI chrNW_004955406:41,706,088...41,716,173
Ensembl chrNW_004955406:41,705,305...41,716,173
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chrNW_004955454:4,573,647...5,199,046
Ensembl chrNW_004955454:4,490,923...5,198,506
JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12600694 NCBI chrNW_004955575:551,991...555,118
Ensembl chrNW_004955575:551,991...555,149
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO associated with Sciatic Neuropathy; RGD PMID:24907405 RGD:8661781 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19220484 PMID:29944862 NCBI chrNW_004955450:945,400...974,129
Ensembl chrNW_004955450:946,898...974,457
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23419392 NCBI chrNW_004955545:1,065,457...1,077,056
Ensembl chrNW_004955545:1,065,457...1,077,526
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15081793 PMID:18690112 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
JBrowse link
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:7816204 PMID:8736133 PMID:11440811 PMID:11875628 PMID:12424556 PMID:12438692 PMID:14575894 PMID:16495007 PMID:17293045 PMID:21268831 PMID:22231481 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9299637 PMID:22231481 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10742108 NCBI chrNW_004955410:31,830,333...31,874,384
Ensembl chrNW_004955410:31,828,506...31,875,100
JBrowse link
G Ctnnd2 catenin delta 2 susceptibility ISO DNA:polymorphism:multiple (human) RGD PMID:24256404 RGD:40902831 NCBI chrNW_004955426:635,287...1,007,389
Ensembl chrNW_004955426:636,225...1,350,784
JBrowse link
G Disc1 DISC1 scaffold protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29643356 NCBI chrNW_004955492:6,946,528...7,239,328
Ensembl chrNW_004955492:6,953,389...7,239,328
JBrowse link
G Dixdc1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chrNW_004955412:13,640,693...13,713,926
Ensembl chrNW_004955412:13,642,078...13,711,850
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23791455 NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO mRNA:decreased expression:hypothalamus: RGD PMID:23529784 RGD:9588317 NCBI chrNW_004955422:28,380,595...28,427,012
Ensembl chrNW_004955422:28,380,591...28,421,301
JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:snp:cds:p.H313H (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9513185 PMID:18305461 PMID:20532872 RGD:1358603 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26415720 NCBI chrNW_004955430:19,280,460...19,287,060
Ensembl chrNW_004955430:19,281,602...19,286,867
JBrowse link
G Esr2 estrogen receptor 2 treatment ISO RGD PMID:24015243 PMID:24631553 RGD:10045678 RGD:7364908 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Fmr1 FMRP translational regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28616095 NCBI chrNW_004955498:566,741...594,837
Ensembl chrNW_004955498:566,688...595,360
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16488545 NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18313124 NCBI chrNW_004955443:2,042,202...2,176,589
Ensembl chrNW_004955443:2,042,151...2,179,174
JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility ISO DNA:snp(s) RGD PMID:22328461 RGD:6480264 NCBI chrNW_004955449:3,964,006...4,001,850
Ensembl chrNW_004955449:3,963,705...4,001,850
JBrowse link
G Glo1 glyoxalase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chrNW_004955437:4,728,709...4,749,834
Ensembl chrNW_004955437:4,728,709...4,749,834
JBrowse link
G Gnb1 G protein subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chrNW_004955486:9,165,850...9,192,306
Ensembl chrNW_004955486:9,165,850...9,193,066
JBrowse link
G Grm8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17434465 NCBI chrNW_004955479:7,520,537...8,279,942
Ensembl chrNW_004955479:7,520,396...8,279,755
JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chrNW_004955446:17,146,915...17,457,843
Ensembl chrNW_004955446:17,151,311...17,457,888
JBrowse link
G Hdac2 histone deacetylase 2 ISO RGD PMID:23485013 RGD:9590265 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707
JBrowse link
G Hmbs hydroxymethylbilane synthase ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:25741868 NCBI chrNW_004955412:20,192,519...20,202,635
Ensembl chrNW_004955412:20,192,522...20,202,635
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:21512427 RGD:5683629 NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO RGD PMID:12040062 RGD:625756 NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO RGD PMID:17074317 RGD:1625000 NCBI chrNW_004955490:912,615...1,126,347
Ensembl chrNW_004955490:910,415...1,126,373
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16828124 PMID:21859099 RGD:6482189 NCBI chrNW_004955425:2,321,420...2,420,420
Ensembl chrNW_004955425:2,321,420...2,420,530
JBrowse link
G Kdm3b lysine demethylase 3B ISO RGD PMID:24397026 RGD:9590119 NCBI chrNW_004955418:2,026,254...2,098,223
Ensembl chrNW_004955418:2,026,254...2,098,223
JBrowse link
G L1cam L1 cell adhesion molecule ISO protein:increased expression: brain, multiple (rat) RGD PMID:19746433 RGD:6483075 NCBI chrNW_004955580:548,442...561,580
Ensembl chrNW_004955580:549,368...561,486
JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659342 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25653350 NCBI chrNW_004955410:6,739,115...7,295,027
Ensembl chrNW_004955410:6,400,242...7,294,924
JBrowse link
G Mapt microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:29860433 NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
JBrowse link
G Mdk midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:19217924 NCBI chrNW_004955422:1,655,351...1,657,026
Ensembl chrNW_004955422:1,655,358...1,657,044
JBrowse link
G Mecp2 methyl-CpG binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22231481 NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288
JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20177408 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Ncor1 nuclear receptor corepressor 1 ISO RGD PMID:20051490 RGD:5688287 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842
JBrowse link
G Npy neuropeptide Y susceptibility ISO CTD Direct Evidence: therapeutic
DNA:SNPs, haplotypes
CTD
RGD
PMID:11440811 PMID:22328461 RGD:6480264 NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297
JBrowse link
G Npy1r neuropeptide Y receptor Y1 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:11440811 PMID:21803058 RGD:10448284 NCBI chrNW_004955403:41,681,834...41,693,094
Ensembl chrNW_004955403:41,681,728...41,694,020
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19815072 NCBI chrNW_004955418:10,953,044...11,107,668
Ensembl chrNW_004955418:10,953,696...11,107,667
JBrowse link
G Rai1 retinoic acid induced 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18285828 NCBI chrNW_004955577:185,404...296,613
Ensembl chrNW_004955577:183,051...200,139
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18272690 NCBI chrNW_004955559:522,466...566,275
Ensembl chrNW_004955559:523,765...564,472
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19120712 NCBI chrNW_004955504:721,470...747,553
Ensembl chrNW_004955504:721,429...747,630
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO OMIM NCBI chrNW_004955481:3,088,440...3,122,421
Ensembl chrNW_004955481:3,088,416...3,125,711
JBrowse link
G Tafa2 TAFA chemokine like family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29339520 NCBI chrNW_004955458:8,935,792...9,351,358 JBrowse link
G Tg thyroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30373627 NCBI chrNW_004955461:7,487,268...7,703,458
Ensembl chrNW_004955461:7,487,322...7,703,363
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20194079 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Ucn urocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16488545 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641
JBrowse link
G Ush2a usherin ISO ClinVar Annotator: match by term: Anxiety ClinVar PMID:9624053 PMID:10090909 PMID:10729113 PMID:10909849 PMID:11402400 PMID:12112664 PMID:12525556 PMID:14970843 PMID:15025721 PMID:15325563 PMID:15326663 PMID:17405132 PMID:18641288 PMID:19881469 PMID:20145675 PMID:20301515 PMID:20507924 PMID:22581970 PMID:24033266 PMID:24088041 PMID:24160897 PMID:24607488 PMID:24944099 PMID:25097241 PMID:25404053 PMID:25649381 PMID:25741868 PMID:26633545 PMID:26872967 PMID:28041643 PMID:28492532 PMID:29953849 PMID:30718709 NCBI chrNW_004955406:1,837,831...2,499,664
Ensembl chrNW_004955406:1,838,885...2,496,980
JBrowse link
acute stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) ISO RGD PMID:20645790 RGD:5509849 NCBI chrNW_004955573:79,606...85,799
Ensembl chrNW_004955573:80,298...85,799
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chrNW_004955454:4,573,647...5,199,046
Ensembl chrNW_004955454:4,490,923...5,198,506
JBrowse link
dopamine beta-hydroxylase deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO OMIM NCBI chrNW_004955513:2,918,085...2,932,481
Ensembl chrNW_004955513:2,918,286...2,932,247
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:21209083 RGD:5685690 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
generalized anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 severity ISO protein:increased expression:serum (human) RGD PMID:27512921 RGD:39938860 NCBI chrNW_004955460:8,790,798...8,794,902
Ensembl chrNW_004955460:8,790,798...8,794,902
JBrowse link
G Slc6a4 solute carrier family 6 member 4 treatment ISO DNA:repeats, haplotype:promoter: RGD PMID:22907732 RGD:36947386 NCBI chrNW_004955481:3,088,440...3,122,421
Ensembl chrNW_004955481:3,088,416...3,125,711
JBrowse link
neurocirculatory asthenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a2 solute carrier family 6 member 2 ISO orthostatic intolerance,OMIM:604715;DNA:point mutation:exon:A457P RGD PMID:10684912 RGD:1624278 NCBI chrNW_004955433:13,170,986...13,216,270
Ensembl chrNW_004955433:13,170,699...13,216,330
JBrowse link
obsessive-compulsive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor ISO RGD PMID:12836135 RGD:734644 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8878350 NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433
JBrowse link
G Comt catechol-O-methyltransferase ISO RGD PMID:11840516 RGD:1300383 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO DNA:tandem repeat polymorphism:3' end: RGD PMID:8832771 RGD:12738360 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:10621951 NCBI chrNW_004955452:3,207,950...3,228,867 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO OMIM NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO RGD PMID:17267119 RGD:6482188 NCBI chrNW_004955425:2,321,420...2,420,420
Ensembl chrNW_004955425:2,321,420...2,420,530
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO OMIM NCBI chrNW_004955481:3,088,440...3,122,421
Ensembl chrNW_004955481:3,088,416...3,125,711
JBrowse link
G Slitrk5 SLIT and NTRK like family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20418887 NCBI chrNW_004955404:21,342,379...21,350,803
Ensembl chrNW_004955404:21,342,379...21,350,464
JBrowse link
Orthostatic Hypotension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12082591 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Gnb3 G protein subunit beta 3 susceptibility ISO DNA:SNP: : 825C>T (human) RGD PMID:11910300 RGD:1580406 NCBI chrNW_004955413:4,440,693...4,447,419
Ensembl chrNW_004955413:4,440,693...4,447,416
JBrowse link
G Oprd1 opioid receptor delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2981652 NCBI chrNW_004955452:7,866,790...7,913,399
Ensembl chrNW_004955452:7,866,758...7,913,399
JBrowse link
G Oprm1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2981652 NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
JBrowse link
Orthostatic Hypotension 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102028532 cytochrome b561 ISO OMIM NCBI chrNW_004955478:8,362,190...8,366,947 JBrowse link
Orthostatic Intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a2 solute carrier family 6 member 2 ISO OMIM NCBI chrNW_004955433:13,170,986...13,216,270
Ensembl chrNW_004955433:13,170,699...13,216,330
JBrowse link
panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505
JBrowse link
G Adra2a adrenoceptor alpha 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:8878350 PMID:15354400 RGD:1358454 NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433
JBrowse link
G Comt catechol-O-methyltransferase ISO OMIM NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
JBrowse link
G Crh corticotropin releasing hormone ISO RGD PMID:14675801 RGD:1358525 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:20817074 PMID:21421022 RGD:5683630 RGD:5683631 NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146
JBrowse link
G Ins insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Maoa amine oxidase [flavin-containing] A ISO RGD PMID:15670397 RGD:1600723 NCBI chrNW_004955516:4,494,133...4,576,317
Ensembl chrNW_004955516:4,493,946...4,576,317
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chrNW_004955405:11,877,474...11,981,035
Ensembl chrNW_004955405:11,886,206...11,982,550
JBrowse link
phobic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15309392 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO DNA:tandem repeat polymorphism:3' end: RGD PMID:8832771 RGD:12738360 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333
JBrowse link
G Med12 mediator complex subunit 12 ISO DNA:mutation:multiple RGD PMID:12216017 RGD:1358728 NCBI chrNW_004955475:10,687,168...10,710,286
Ensembl chrNW_004955475:10,687,367...10,710,053
JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2554359 NCBI chrNW_004955483:4,495,257...4,503,377 JBrowse link
post-traumatic stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO RGD PMID:23381833 RGD:10054113 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility ISO DNA:missense mutation:cds:196G>A (p.V66M) (human) RGD PMID:23319005 RGD:10059367 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Casp9 caspase 9 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:21714072 RGD:5147887 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO RGD PMID:23174211 RGD:10412309 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO mRNA, protein:altered expression:locus coeruleus (rat) RGD PMID:21584742 RGD:5686336 NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO protein:increased expression:hippocampus RGD PMID:20863519 RGD:5684783 NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 ISO RGD PMID:25331812 RGD:13782181 NCBI chrNW_004955416:10,197,957...10,221,104
Ensembl chrNW_004955416:10,198,099...10,220,792
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein treatment ISO RGD PMID:17968352 RGD:8694407 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610
JBrowse link
separation anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd4 dopamine receptor D4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20731709 NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960
JBrowse link
social phobia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntnap2 contactin associated protein 2 susceptibility ISO DNA:SNP: :rs2710102(human) RGD PMID:21193173 RGD:13450911 NCBI chrNW_004955491:1,983,002...3,982,510
Ensembl chrNW_004955491:1,984,050...3,981,830
JBrowse link
Vasovagal Syncope term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppb natriuretic peptide B ISO associated with Syncope;protein:increased expression:serum: RGD PMID:23373852 RGD:7247623 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12678
    disease of anatomical entity 12356
      nervous system disease 10304
        central nervous system disease 9020
          brain disease 8465
            disease of mental health 6162
              cognitive disorder 1623
                anxiety disorder 93
                  Neuroticism 0
                  acute stress disorder + 13
                  generalized anxiety disorder 2
                  neurocirculatory asthenia + 9
                  neurotic disorder 0
                  obsessive-compulsive disorder + 9
                  panic disorder + 10
                  phobic disorder + 5
                  post-traumatic stress disorder 11
                  separation anxiety disorder 1
paths to the root