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ONTOLOGY REPORT - ANNOTATIONS


Term:sex cord-gonadal stromal tumor
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Accession:DOID:192 term browser browse the term
Definition:Neoplasms derived from the primitive sex cord or gonadal stromal cells of the embryonic GONADS. They are classified by their presumed histogenesis and differentiation. From the sex cord, there are SERTOLI CELL TUMOR and GRANULOSA CELL TUMOR; from the gonadal stroma, LEYDIG CELL TUMOR and THECOMA. These tumors may be identified in either the OVARY or the TESTIS.
Synonyms:exact_synonym: Gynandroblastoma;   Sex Cord Stromal Tumor;   Sex Cord-Stromal Tumors;   gynandroblastomas;   sex cord stromal tumour;   sex cord-gonadal stromal tumour;   sex cord-stromal neoplasm;   specialized gonadal neoplasm;   specialized gonadal tumor;   specialized gonadal tumour
 narrow_synonym: malignant testicular sex cord-stromal tumor;   malignant testicular sex cord-stromal tumour
 primary_id: MESH:D018312
 xref: NCI:C3794
For additional species annotation, visit the Alliance of Genome Resources.


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sex cord-gonadal stromal tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2301690
granulosa cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amh anti-Mullerian hormone JBrowse link 7 11,775,155 11,777,503 RGD:2315639
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1643593
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289157
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2296066
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:2296066
G Cmklr1 chemerin chemokine-like receptor 1 JBrowse link 12 48,743,556 48,796,582 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1643593
RGD:13592920
G Fancf FA complementation group F JBrowse link 1 107,229,516 107,232,321 RGD:2298508
RGD:11049141
G Fhit fragile histidine triad diadenosine triphosphatase JBrowse link 15 15,697,292 16,862,873 RGD:2298508
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:2289157
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:8554872
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2302173
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:11554173
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:2302176
RGD:2289157
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:2317693
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 6 51,265,509 51,356,383 RGD:2289157
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2289157
G Rarres2 retinoic acid receptor responder 2 JBrowse link 4 78,205,809 78,208,956 RGD:11554173
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:2289157
G Smad1 SMAD family member 1 JBrowse link 19 32,182,942 32,248,694 RGD:2299978
G Smad5 SMAD family member 5 JBrowse link 17 8,307,448 8,336,996 RGD:2299978
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315091
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315463
G Wif1 Wnt inhibitory factor 1 JBrowse link 7 63,094,955 63,165,158 RGD:1643593
Granulosa Cell Tumor of the Ovary term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:8554872
Leydig cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:2293582
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:2293582
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:2293633
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:2290041
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2301251
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290379
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:11554173
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:2302176
RGD:11554173
RGD:2292537
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:2298579
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:2298579
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:2298579
RGD:2298580
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2298579
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:11554173
G Prmt5 protein arginine methyltransferase 5 JBrowse link 15 33,156,508 33,165,893 RGD:2299953
multinodular goiter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:8554872
RGD:7240710
Sertoli cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290369
Sertoli-Leydig cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290367
Somatic Leydig Cell Adenoma, with Male-Limited Precocious Puberty term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:8554872
Thecoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15608
    disease of anatomical entity 14965
      reproductive system disease 2449
        reproductive organ cancer 1014
          sex cord-gonadal stromal tumor 39
            Leydig cell tumor + 14
            Ovarian Gynandroblastoma 0
            Sertoli cell tumor 1
            Sertoli-Leydig cell tumor + 2
            Thecoma + 1
            granulosa cell tumor + 24
            luteoma 0
            ovarian sex-cord stromal tumor 0
            testicular sex cord-stromal neoplasm + 0
Path 2
Term Annotations click to browse term
  disease 15608
    disease of anatomical entity 14965
      Urogenital Diseases 4004
        reproductive system disease 2449
          reproductive organ cancer 1014
            sex cord-gonadal stromal tumor 39
              Leydig cell tumor + 14
              Ovarian Gynandroblastoma 0
              Sertoli cell tumor 1
              Sertoli-Leydig cell tumor + 2
              Thecoma + 1
              granulosa cell tumor + 24
              luteoma 0
              ovarian sex-cord stromal tumor 0
              testicular sex cord-stromal neoplasm + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.