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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:malignant fibrous histiocytoma
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Accession:DOID:1907 term browser browse the term
Definition:The most commonly diagnosed soft tissue sarcoma. It is a neoplasm with a fibrohistiocytic appearance found chiefly in later adult life, with peak incidence in the 7th decade.
Synonyms:exact_synonym: Fibroxanthosarcoma;   MFH;   malignant fibrohistiocytic tumor;   malignant fibrohistiocytic tumors;   malignant fibrous histiocytomas;   malignant fibroxanthoma;   pleomorphic malignant fibrous histiocytoma
 primary_id: MESH:D051677
 xref: NCI:C4247;   NCI:C60442
For additional species annotation, visit the Alliance of Genome Resources.


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malignant fibrous histiocytoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha treatment ISO human cell line in mouse model RGD PMID:23166610 RGD:7242013 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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Angiomatoid Fibrous Histiocytoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 ISO OMIM NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17126
    disease of cellular proliferation 6943
      Neoplasms by Histologic Type 4764
        cell type cancer 3390
          sarcoma 243
            malignant fibrous histiocytoma 2
              Angiomatoid Fibrous Histiocytoma 1
              malignant fibrous histiocytoma of bone 0
              malignant inflammatory fibrous histiocytoma 0
Path 2
Term Annotations click to browse term
  disease 17126
    disease of anatomical entity 16474
      nervous system disease 12073
        peripheral nervous system disease 2516
          neuropathy 2316
            neuromuscular disease 1829
              muscular disease 1229
                muscle tissue disease 820
                  Muscle Tissue Neoplasms 139
                    musculoskeletal system benign neoplasm 81
                      connective tissue benign neoplasm 29
                        histiocytoma 6
                          malignant fibrous histiocytoma 2
                            Angiomatoid Fibrous Histiocytoma 1
                            malignant fibrous histiocytoma of bone 0
                            malignant inflammatory fibrous histiocytoma 0
paths to the root