RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: neuritis
Accession: DOID:1803
browse the term
Definition: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
Synonyms: exact_synonym: Peripheral Neuritides; Peripheral Neuritis; Polyneuritides; Polyneuritis; Sensory Neuritides; neuritides; sensory neuritis
primary_id: MESH:D009443
alt_id: RDO:0006205
xref: NCI:C116381
For additional species annotation, visit the
Alliance of Genome Resources .
G
Septin9
septin 9
ISO
hereditary neuralgic amyotrophy, OMIM:604061 ClinVar Annotator: match by term: Amyotrophic neuralgia | ClinVar Annotator: match by term: Amyotrophy, hereditary neuralgic | ClinVar Annotator: match by term: Hereditary Neuralgic Amyotrophy (HNA) CTD Direct Evidence: marker/mechanism
ClinVar CTD OMIM RGD
PMID:16186812 PMID:17546647 PMID:18492087 PMID:19139049 PMID:19204161 PMID:19451530 PMID:20019224 PMID:20301569 PMID:22981636 PMID:25741868 PMID:26467025 PMID:28492532 PMID:28503616 PMID:31619932 PMID:16186812 More...
RGD:1599349
NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055
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Ttr
transthyretin
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Carpal tunnel syndrome | ClinVar Annotator: match by term: Carpal tunnel syndrome, familial
CTD ClinVar
PMID:192115 PMID:1335038 PMID:1351039 PMID:1353008 PMID:1358785 PMID:1490495 PMID:1547960 PMID:1570831 PMID:1786038 PMID:1867256 PMID:1977686 PMID:1979335 PMID:1981182 PMID:1992765 PMID:1997217 PMID:2002274 PMID:2046936 PMID:2063870 PMID:2237288 PMID:2320592 PMID:2349941 PMID:2363717 PMID:2564060 PMID:2590199 PMID:2624269 PMID:2646319 PMID:2714785 PMID:2840822 PMID:2856994 PMID:2857043 PMID:2877582 PMID:2891727 PMID:2896079 PMID:3011930 PMID:3022107 PMID:3022108 PMID:3022697 PMID:3030336 PMID:3229002 PMID:3457802 PMID:3479441 PMID:3627183 PMID:3762958 PMID:3908483 PMID:3934968 PMID:4079954 PMID:4138132 PMID:4354899 PMID:5507249 PMID:5652991 PMID:5799493 PMID:6087811 PMID:6100724 PMID:6208668 PMID:6311926 PMID:6549130 PMID:6583672 PMID:6651852 PMID:6736244 PMID:6782125 PMID:6801514 PMID:7389759 PMID:7608709 PMID:7655883 PMID:7839813 PMID:7868124 PMID:7914929 PMID:8038017 PMID:8064809 PMID:8071954 PMID:8081397 PMID:8100581 PMID:8133316 PMID:8194279 PMID:8275943 PMID:8345041 PMID:8428916 PMID:8509786 PMID:8563114 PMID:8698351 PMID:8721565 PMID:8778271 PMID:8784093 PMID:8830175 PMID:8857732 PMID:9017939 PMID:9090525 PMID:9215058 PMID:9268242 PMID:9475090 PMID:9748014 PMID:9771673 PMID:10211412 PMID:10439123 PMID:10453736 PMID:10465115 PMID:10488818 PMID:10506096 PMID:10529370 PMID:10611950 PMID:10671063 PMID:10762172 PMID:10842715 PMID:10923048 PMID:11385707 PMID:11418763 PMID:11523162 PMID:11709003 PMID:11752419 PMID:11752443 PMID:11866053 PMID:11940682 PMID:12039669 PMID:12050338 PMID:12217248 PMID:12433265 PMID:12566023 PMID:12617705 PMID:12874413 PMID:12874414 PMID:14569203 PMID:14640030 PMID:14640031 PMID:14673473 PMID:14986482 PMID:15123043 PMID:15185492 PMID:15249622 PMID:15523922 PMID:15645642 PMID:15753613 PMID:15820680 PMID:15930086 PMID:16011990 PMID:16194874 PMID:16194875 PMID:16432141 PMID:16439621 PMID:16631014 PMID:16631015 PMID:17062380 PMID:17251346 PMID:17338921 PMID:17443043 PMID:17503405 PMID:17551924 PMID:17698792 PMID:18022643 PMID:18042262 PMID:18276611 PMID:18318779 PMID:18460047 PMID:18506713 PMID:18606975 PMID:18830126 PMID:18863976 PMID:18925456 PMID:19364362 PMID:19602727 PMID:19709674 PMID:19781421 PMID:19808383 PMID:20209591 PMID:20301373 PMID:20435197 PMID:20697105 PMID:20714957 PMID:20840742 PMID:20937937 PMID:20981092 PMID:21520333 PMID:21540676 PMID:21600538 PMID:21692911 PMID:22083004 PMID:22184092 PMID:22382560 PMID:22412233 PMID:22531659 PMID:22551192 PMID:22592564 PMID:22620962 PMID:22620967 PMID:22745357 PMID:22877808 PMID:22928869 PMID:22995991 PMID:23080516 PMID:23193944 PMID:23240369 PMID:23279339 PMID:23387326 PMID:23713495 PMID:23716704 PMID:23797140 PMID:23833285 PMID:23993291 PMID:24033266 PMID:24046394 PMID:24053266 PMID:24073013 PMID:24101130 PMID:24131106 PMID:24164154 PMID:24184229 PMID:24356794 PMID:24455802 PMID:24474780 PMID:24480837 PMID:24517438 PMID:24555660 PMID:24563469 PMID:24601850 PMID:24633258 PMID:24767411 PMID:24800914 PMID:24818650 PMID:25395306 PMID:25519307 PMID:25525159 PMID:25550818 PMID:25551524 PMID:25636337 PMID:25741868 PMID:25819286 PMID:25846356 PMID:25973863 PMID:25997029 PMID:26002815 PMID:26017327 PMID:26088020 PMID:26096568 PMID:26104852 PMID:26115039 PMID:26115788 PMID:26123279 PMID:26208957 PMID:26243339 PMID:26369527 PMID:26428663 PMID:26467025 PMID:26513367 PMID:26521788 PMID:26529114 PMID:26537620 PMID:26587769 PMID:26656838 PMID:26894299 PMID:27025994 PMID:27066555 PMID:27188913 PMID:27273296 PMID:27350016 PMID:27386769 PMID:27532257 PMID:27589730 PMID:27618855 PMID:27652282 PMID:27720586 PMID:27758856 PMID:27793437 PMID:27838833 PMID:28102864 PMID:28188196 PMID:28434346 PMID:28475415 PMID:28492532 PMID:28635949 PMID:28762097 PMID:28882124 PMID:29052438 PMID:29121657 PMID:29407121 PMID:29423915 PMID:29493581 PMID:29520877 PMID:29540472 PMID:29607936 PMID:29764897 PMID:29875424 PMID:29883834 PMID:29970125 PMID:30019395 PMID:30070416 PMID:30093168 PMID:30198232 PMID:30213731 PMID:30243104 PMID:30295933 PMID:30328212 PMID:30336828 PMID:30350904 PMID:30361054 PMID:30572722 PMID:30683924 PMID:30811423 PMID:30813263 PMID:30938420 PMID:31006018 PMID:31018485 PMID:31103217 PMID:31135624 PMID:31139689 PMID:31343308 PMID:31343348 PMID:31348283 PMID:31359320 PMID:31371117 PMID:31502881 PMID:31554435 PMID:31589614 PMID:31659433 PMID:31718691 PMID:31728576 PMID:31740141 PMID:31821430 PMID:31919945 PMID:31980526 PMID:32150461 PMID:32269295 PMID:32376792 PMID:32399692 PMID:32461654 PMID:32528171 PMID:32674397 PMID:32746448 PMID:32852783 PMID:32880476 PMID:32893242 PMID:32925285 PMID:33094885 PMID:33373035 PMID:33411102 PMID:33467513 PMID:33726816 PMID:33739616 PMID:34047656 PMID:34079032 PMID:34380564 PMID:34440326 PMID:34658264 PMID:34729535 PMID:34746851 PMID:35115086 PMID:35377943 PMID:35417510 PMID:35592550 PMID:35637921 PMID:35665045 PMID:35730447 PMID:35841533 PMID:35903975 PMID:37091313 More...
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Ttr
transthyretin
ISO
ClinVar Annotator: match by term: Carpal tunnel syndrome 1
OMIM ClinVar
PMID:192115 PMID:1335038 PMID:1351039 PMID:1353008 PMID:1358785 PMID:1490495 PMID:1547960 PMID:1570831 PMID:1786038 PMID:1867256 PMID:1977686 PMID:1979335 PMID:1981182 PMID:1992765 PMID:1997217 PMID:2002274 PMID:2063870 PMID:2237288 PMID:2320592 PMID:2349941 PMID:2363717 PMID:2564060 PMID:2590199 PMID:2624269 PMID:2646319 PMID:2714785 PMID:2840822 PMID:2856994 PMID:2857043 PMID:2877582 PMID:2891727 PMID:2896079 PMID:3011930 PMID:3022107 PMID:3022108 PMID:3022697 PMID:3030336 PMID:3229002 PMID:3457802 PMID:3479441 PMID:3627183 PMID:3762958 PMID:3908483 PMID:3934968 PMID:4079954 PMID:4138132 PMID:4354899 PMID:5507249 PMID:5652991 PMID:5799493 PMID:6087811 PMID:6100724 PMID:6208668 PMID:6311926 PMID:6549130 PMID:6583672 PMID:6651852 PMID:6736244 PMID:6782125 PMID:6801514 PMID:7389759 PMID:7608709 PMID:7655883 PMID:7839813 PMID:7868124 PMID:7914929 PMID:8038017 PMID:8064809 PMID:8071954 PMID:8081397 PMID:8100581 PMID:8133316 PMID:8194279 PMID:8275943 PMID:8309582 PMID:8345041 PMID:8428916 PMID:8509786 PMID:8563114 PMID:8698351 PMID:8778271 PMID:8784093 PMID:8830175 PMID:8857732 PMID:9017939 PMID:9090525 PMID:9215058 PMID:9268242 PMID:9475090 PMID:9748014 PMID:9771673 PMID:10211412 PMID:10439123 PMID:10453736 PMID:10465115 PMID:10506096 PMID:10529370 PMID:10611950 PMID:10671063 PMID:10762172 PMID:10842715 PMID:10923048 PMID:11385707 PMID:11418763 PMID:11523162 PMID:11709003 PMID:11752419 PMID:11752443 PMID:11940682 PMID:12039669 PMID:12050338 PMID:12217248 PMID:12433265 PMID:12566023 PMID:12617705 PMID:12874413 PMID:12874414 PMID:14569203 PMID:14640030 PMID:14640031 PMID:14673473 PMID:14986482 PMID:15123043 PMID:15185492 PMID:15249622 PMID:15523922 PMID:15645642 PMID:15753613 PMID:15820680 PMID:15930086 PMID:16011990 PMID:16194874 PMID:16194875 PMID:16432141 PMID:16439621 PMID:16631014 PMID:16631015 PMID:17062380 PMID:17251346 PMID:17338921 PMID:17443043 PMID:17503405 PMID:17551924 PMID:17698792 PMID:18022643 PMID:18042262 PMID:18276611 PMID:18318779 PMID:18460047 PMID:18506713 PMID:18606975 PMID:18830126 PMID:18863976 PMID:18925456 PMID:19364362 PMID:19602727 PMID:19709674 PMID:19781421 PMID:19808383 PMID:20209591 PMID:20301373 PMID:20435197 PMID:20697105 PMID:20714957 PMID:20840742 PMID:20937937 PMID:20981092 PMID:21520333 PMID:21540676 PMID:21600538 PMID:21692911 PMID:22083004 PMID:22184092 PMID:22382560 PMID:22412233 PMID:22531659 PMID:22551192 PMID:22592564 PMID:22620962 PMID:22620967 PMID:22745357 PMID:22877808 PMID:22928869 PMID:22995991 PMID:23080516 PMID:23193944 PMID:23240369 PMID:23387326 PMID:23713495 PMID:23716704 PMID:23797140 PMID:23833285 PMID:23993291 PMID:24033266 PMID:24046394 PMID:24053266 PMID:24073013 PMID:24101130 PMID:24131106 PMID:24164154 PMID:24184229 PMID:24356794 PMID:24455802 PMID:24474780 PMID:24480837 PMID:24517438 PMID:24555660 PMID:24563469 PMID:24601850 PMID:24633258 PMID:24767411 PMID:24800914 PMID:24818650 PMID:25395306 PMID:25519307 PMID:25525159 PMID:25550818 PMID:25551524 PMID:25636337 PMID:25741868 PMID:25819286 PMID:25846356 PMID:25973863 PMID:25997029 PMID:26002815 PMID:26017327 PMID:26088020 PMID:26096568 PMID:26104852 PMID:26115039 PMID:26115788 PMID:26123279 PMID:26208957 PMID:26243339 PMID:26369527 PMID:26428663 PMID:26467025 PMID:26513367 PMID:26521788 PMID:26529114 PMID:26537620 PMID:26587769 PMID:26656838 PMID:26894299 PMID:27025994 PMID:27066555 PMID:27188913 PMID:27273296 PMID:27386769 PMID:27532257 PMID:27589730 PMID:27618855 PMID:27652282 PMID:27720586 PMID:27758856 PMID:27793437 PMID:27838833 PMID:28102864 PMID:28434346 PMID:28475415 PMID:28492532 PMID:28635949 PMID:28762097 PMID:28882124 PMID:29052438 PMID:29121657 PMID:29407121 PMID:29423915 PMID:29493581 PMID:29520877 PMID:29540472 PMID:29607936 PMID:29764897 PMID:29875424 PMID:29970125 PMID:30019395 PMID:30070416 PMID:30093168 PMID:30198232 PMID:30213731 PMID:30243104 PMID:30295933 PMID:30328212 PMID:30336828 PMID:30350904 PMID:30361054 PMID:30572722 PMID:30683924 PMID:30813263 PMID:30938420 PMID:31006018 PMID:31018485 PMID:31103217 PMID:31135624 PMID:31139689 PMID:31343308 PMID:31343348 PMID:31348283 PMID:31359320 PMID:31371117 PMID:31502881 PMID:31554435 PMID:31589614 PMID:31659433 PMID:31718691 PMID:31728576 PMID:31740141 PMID:31821430 PMID:31919945 PMID:31980526 PMID:32150461 PMID:32269295 PMID:32376792 PMID:32399692 PMID:32461654 PMID:32528171 PMID:32674397 PMID:32746448 PMID:32852783 PMID:32880476 PMID:32893242 PMID:32925285 PMID:33373035 PMID:33411102 PMID:33467513 PMID:33726816 PMID:33739616 PMID:34047656 PMID:34079032 PMID:34380564 PMID:34440326 PMID:34658264 PMID:34729535 PMID:34746851 PMID:35115086 PMID:35377943 PMID:35417510 PMID:35592550 PMID:35637921 PMID:35665045 PMID:35730447 PMID:35841533 PMID:35903975 PMID:37091313 More...
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Comp
cartilage oligomeric matrix protein
ISO
ClinVar Annotator: match by term: Carpal tunnel syndrome 2
OMIM ClinVar
PMID:12483304 PMID:14684695 PMID:21834907 PMID:21965141 PMID:24595329 PMID:25741868 PMID:28492532 PMID:32686688 More...
NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
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Adam8
ADAM metallopeptidase domain 8
ISO
RGD
PMID:9670863
RGD:2325244
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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Aif1
allograft inflammatory factor 1
IEP
protein:increased expression:spinal cord (rat)
RGD
PMID:15710454
RGD:2313042
NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Anxa1
annexin A1
IEP
protein:increased expression:sciatic nerve
RGD
PMID:10603033
RGD:2306914
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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App
amyloid beta precursor protein
treatment
IDA
RGD
PMID:28446186
RGD:13782060
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Cav1
caveolin 1
IEP
protein:increased phosphorylation:sciatic nerve
RGD
PMID:17234162
RGD:2289125
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Ccr1
C-C motif chemokine receptor 1
ISO
protein:increased expression:sciatic nerve, macrophage, T cell
RGD
PMID:20500551
RGD:5688140
NCBI chr 8:123,556,286...123,561,841
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Cd14
CD14 molecule
severity
IEP
RGD
PMID:19162137
RGD:2312712
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd28
Cd28 molecule
IMP
RGD
PMID:12864982
RGD:2307204
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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Cd40
CD40 molecule
IEP
RGD
PMID:17188497
RGD:5491181
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd40lg
CD40 ligand
IEP
RGD
PMID:17188497
RGD:5491181
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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Cd59b
CD59b molecule
IEP
protein:increased expression:Schwann cell (rat)
RGD
PMID:10450801
RGD:1600494
NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
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Cx3cl1
C-X3-C motif chemokine ligand 1
IEP
RGD
PMID:18448252
RGD:4891968
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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Cx3cr1
C-X3-C motif chemokine receptor 1
IEP
RGD
PMID:18448252
RGD:4891968
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Dcc
DCC netrin 1 receptor
IEP
RGD
PMID:16337279
RGD:2314374
NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740
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Dhodh
dihydroorotate dehydrogenase (quinone)
treatment
IMP
RGD
PMID:11522581
RGD:11040446
NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
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Epas1
endothelial PAS domain protein 1
IEP
RGD
PMID:23603807
RGD:10395381
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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Epo
erythropoietin
IEP
RGD
PMID:20361946
RGD:10400894
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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Foxp3
forkhead box P3
IEP
protein:decreased expression:sciatic nerve
RGD
PMID:30464413
RGD:38549576
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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Havcr2
hepatitis A virus cellular receptor 2
disease_progression
IEP
mRNA,protein:increased expression:sciatic nerve:
RGD
PMID:21784136
RGD:9686114
NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
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Hif1a
hypoxia inducible factor 1 subunit alpha
IEP
RGD
PMID:23603807
RGD:10395381
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
disease_progression
IMP
RGD
PMID:17286627
RGD:5508466
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Ifnb1
interferon beta 1
ameliorates
IDA
RGD
PMID:10494101
RGD:401854240
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Il17a
interleukin 17A
ISO IEP
mRNA, protein:increased expression:sciatic nerve, inguinal lymph node
RGD
PMID:10785455 PMID:19207263
RGD:4888513 , RGD:4831923
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il1b
interleukin 1 beta
treatment
IEP
RGD
PMID:18400050
RGD:7401218
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il5
interleukin 5
treatment
IDA
RGD
PMID:22310911
RGD:11522768
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Mmp7
matrix metallopeptidase 7
IEP
RGD
PMID:9546322
RGD:9685357
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp9
matrix metallopeptidase 9
IEP
RGD
PMID:9546322
RGD:9685357
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Nos2
nitric oxide synthase 2
IEP
protein:increased expression:nerve root, leukocyte, Schwann cell (rat)
RGD
PMID:15144861
RGD:1580265
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Ptgs1
prostaglandin-endoperoxide synthase 1
IEP
protein:increased expression:
RGD
PMID:12916703
RGD:5688236
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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Ptgs2
prostaglandin-endoperoxide synthase 2
IEP
protein:increased expression:
RGD
PMID:12916703
RGD:5688236
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rhoa
ras homolog family member A
IEP
protein:increased expression:spinal ganglion, macrophage, T cell
RGD
PMID:17367505
RGD:1642966
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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Spp1
secreted phosphoprotein 1
IDA
RGD
PMID:15531104
RGD:1581323
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Tlr2
toll-like receptor 2
severity
IEP
RGD
PMID:19162137
RGD:2312712
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
IEP
mRNA:increased expression:multiple tissues
RGD
PMID:18434754
RGD:2312677
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
G
Tlr9
toll-like receptor 9
IEP
mRNA:increased expression:multiple tissues
RGD
PMID:18434754
RGD:2312677
NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
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Tnf
tumor necrosis factor
treatment
IEP
RGD
PMID:18400050
RGD:7401218
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Trem1
triggering receptor expressed on myeloid cells 1
ameliorates
IDA IEP
mRNA:increased expression:sciatic nerve,peripheral blood mononuclar cell
RGD
PMID:28260057 PMID:28260057
RGD:127284841 , RGD:127284841
NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
G
Bag1
BAG cochaperone 1
IEP
RGD
PMID:23108487
RGD:13506903
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
G
Rgs3
regulator of G-protein signaling 3
IEP
mRNA:decreased expression:dorsal root ganglion
RGD
PMID:14550772
RGD:13524539
NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894
G
Rgs4
regulator of G-protein signaling 4
IEP
mRNA:decreased expression:dorsal root ganglion
RGD
PMID:14550772
RGD:13524539
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
G
Egfr
epidermal growth factor receptor
IEP
RGD
PMID:18845940
RGD:126790486
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Erbb2
erb-b2 receptor tyrosine kinase 2
IEP
RGD
PMID:19296522
RGD:10449020
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
G
Erbb3
erb-b2 receptor tyrosine kinase 3
IEP
RGD
PMID:19296522 PMID:18845940
RGD:10449020 , RGD:126790486
NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
G
Erbb4
erb-b2 receptor tyrosine kinase 4
IEP
RGD
PMID:19296522 PMID:18845940
RGD:10449020 , RGD:126790486
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
G
Mt1
metallothionein 1
IEP
RGD
PMID:22253198
RGD:6483815
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Mt2A
metallothionein 2A
IEP
mRNA:decreased expression:left median nerve (rat)
RGD
PMID:22253198
RGD:6483815
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mt3
metallothionein 3
treatment
IEP
RGD
PMID:22253198
RGD:6483815
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
G
Npy
neuropeptide Y
IEP
RGD
PMID:19456245
RGD:10448955
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
G
Nrg1
neuregulin 1
IEP
RGD
PMID:19296522
RGD:10449020
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
G
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
ISO
ClinVar Annotator: match by term: Mononeuropathy of the Median Nerve
ClinVar
PMID:25741868 PMID:26467025 PMID:28492532
NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083
G
Abcc8
ATP binding cassette subfamily C member 8
IEP
protein:decreased expression:spinal cord
RGD
PMID:21907492
RGD:12791994
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Abcc9
ATP binding cassette subfamily C member 9
IEP
protein:decreased expression:spinal cord
RGD
PMID:21907492
RGD:12791994
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
G
Adrb2
adrenoceptor beta 2
treatment
ISO
RGD
PMID:19912227
RGD:8548489
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
G
Agt
angiotensinogen
IDA
RGD
PMID:20886512
RGD:5129198
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
G
Akap12
A-kinase anchoring protein 12
IEP
mRNA,protein:increased expression:spinal cord:
RGD
PMID:19937403
RGD:14348968
NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
G
Amigo3
adhesion molecule with Ig like domain 3
IEP
protein:increased expression:dorsal root ganglion (rat)
RGD
PMID:23613963
RGD:14390159
NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
G
Apoa1
apolipoprotein A1
IEP
protein:increased expression:sciatic nerve:
RGD
PMID:2493483
RGD:7495790
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
G
Apoe
apolipoprotein E
IEP
protein:increased expression:sciatic nerve:
RGD
PMID:2493483
RGD:7495790
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Bdkrb1
bradykinin receptor B1
IMP
RGD
PMID:18182225
RGD:5129227
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
G
Bdkrb2
bradykinin receptor B2
IEP
RGD
PMID:18182225
RGD:5129227
NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
G
Bdnf
brain-derived neurotrophic factor
treatment
IEP IDA
protein:increased expression:dorsal root ganglion:
RGD
PMID:22309829 PMID:24388817
RGD:8657100 , RGD:10059363
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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C3
complement C3
IEP
protein:increased expression:sciatic nerve
RGD
PMID:18052971
RGD:5129535
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
Cacna1d
calcium voltage-gated channel subunit alpha1 D
IEP
mRNA:decreased expression:spinal cord dorsal horn
RGD
PMID:16026470
RGD:6906922
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
G
Cacna1h
calcium voltage-gated channel subunit alpha1 H
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:22972512
RGD:15042903
NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
G
Cacna1i
calcium voltage-gated channel subunit alpha1 I
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:22972512
RGD:15042903
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
G
Calca
calcitonin-related polypeptide alpha
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19852068
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Capn1
calpain 1
IEP
protein:increased expression:skeletal muscle tissue of tibialis anterior
RGD
PMID:24745757
RGD:13792589
NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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Capn2
calpain 2
IEP
protein:increased expression:skeletal muscle tissue of tibialis anterior
RGD
PMID:24745757
RGD:13792589
NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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Casp12
caspase 12
IDA
mRNA, protein:increased expression:dorsal root ganglion
RGD
PMID:29659443
RGD:13782273
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
G
Casp3
caspase 3
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:29659443
RGD:13782273
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp7
caspase 7
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:29659443
RGD:13782273
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Casp8
caspase 8
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:29659443
RGD:13782273
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Cat
catalase
IEP
protein:decreased activity:sciatic nerve, spinal cord, dorsal root ganglion:
RGD
PMID:19675389
RGD:9479064
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav1
caveolin 1
IEP
protein:decreased expression:spinal cord, blood vessel
RGD
PMID:21795534
RGD:6784526
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Ccl2
C-C motif chemokine ligand 2
IEP ISO
protein:increased expression:spinal cord dorsal horn, axon terminal (rat) protein:increased expression:lumbar dorsal root ganglion (mouse)
RGD
PMID:19059387 PMID:22564672
RGD:2307005 , RGD:8549487
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl5
C-C motif chemokine ligand 5
IEP
mRNA:increased expression:sciatic nerve (rat)
RGD
PMID:19152028
RGD:4890004
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccr2
C-C motif chemokine receptor 2
ISO
RGD
PMID:24907405
RGD:8661781
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
IEP
protein:decreased expression:sciatic nerve
RGD
PMID:21959983
RGD:10045367
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cers2
ceramide synthase 2
IEP
mRNA,protein:decreased expression:sciatic nerve:
RGD
PMID:22393241
RGD:11041067
NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
G
Cnr2
cannabinoid receptor 2
treatment
IDA
RGD
PMID:19345493
RGD:2316195
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Crcp
CGRP receptor component
IEP
RGD
PMID:12895509
RGD:727768
NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
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Creb1
cAMP responsive element binding protein 1
treatment
IEP IDA
protein:increased phosphorylation:nucleus
RGD
PMID:19918364 PMID:33596416
RGD:10059430 , RGD:401960870
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Crh
corticotropin releasing hormone
IEP
mRNA:increased expression:central nucleus of amygdala, bed nucleus of stria terminalis (rat)
RGD
PMID:21684787
RGD:5490542
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Cx3cr1
C-X3-C motif chemokine receptor 1
treatment
ISO IEP
RGD
PMID:20524966 PMID:15341587 PMID:20921832
RGD:9354422 , RGD:1358720 , RGD:9491396
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
IEP
protein:increased expression:spinal cord dorsal horn (rat)
RGD
PMID:16632873
RGD:4889134
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
IEP
mRNA:decreased expression:spinal cord (rat)
RGD
PMID:17720801
RGD:4889112
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Dbn1
drebrin 1
IEP
protein:increased expression:neuron:
RGD
PMID:11578820
RGD:10398813
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
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Dnmt3a
DNA methyltransferase 3 alpha
ISO
protein:increased expression:brain:
RGD
PMID:22031875
RGD:9589072
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
G
Elavl4
ELAV like RNA binding protein 4
IEP
RGD
PMID:12957493
RGD:1579851
NCBI chr 5:125,056,848...125,200,543
Ensembl chr 5:125,056,848...125,200,446
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Fas
Fas cell surface death receptor
IEP
RGD
PMID:29970988
RGD:13792563
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Fgfr1
Fibroblast growth factor receptor 1
IEP
mRNA:increased expression:neuron:
RGD
PMID:8971765
RGD:10402092
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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Fto
FTO, alpha-ketoglutarate dependent dioxygenase
IMP
RGD
PMID:36545239 PMID:33829413
RGD:329951012 , RGD:329951014
NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
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Fubp1
far upstream element binding protein 1
IEP
RGD
PMID:23939805
RGD:13673880
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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Gc
GC, vitamin D binding protein
ISO
protein:increased expression:nerve
RGD
PMID:15509515
RGD:2316214
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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Gch1
GTP cyclohydrolase 1
IEP
protein:increased expression:dorsal horn of spinal cord
RGD
PMID:23515624
RGD:401700393
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
G
Gdnf
glial cell derived neurotrophic factor
IEP
mRNA:increased expression:sciatic nerve
RGD
PMID:10852218
RGD:6218977
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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Gfra1
GDNF family receptor alpha 1
IEP
protein:increased expression:spinal cord dorsal horn
RGD
PMID:20533358
RGD:6218963
NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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Gfra3
GDNF family receptor alpha 3
IEP
mRNA:increased expression:sciatic nerve
RGD
PMID:10852218
RGD:6218977
NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
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Gpx3
glutathione peroxidase 3
treatment
IEP
RGD
PMID:28508406
RGD:401827908
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
IEP
RGD
PMID:26656067
RGD:13792690
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
IEP
RGD
PMID:26656067
RGD:13792690
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Gsk3b
glycogen synthase kinase 3 beta
IDA
RGD
PMID:27125978
RGD:13792740
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hgf
hepatocyte growth factor
treatment
ISO
RGD
PMID:18941443
RGD:8548631
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Hmgb1
high mobility group box 1
treatment
IMP
RGD
PMID:23991202
RGD:10402062
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hmox1
heme oxygenase 1
treatment
IDA
RGD
PMID:23224421
RGD:10755722
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hrh3
histamine receptor H3
IDA
RGD
PMID:17350523
RGD:1626418
NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
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Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IEP
mRNA:increased expression:fourth lumbar dorsal root ganglion (rat)
RGD
PMID:12648755
RGD:632873
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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Icam1
intercellular adhesion molecule 1
IEP
RGD
PMID:20546684
RGD:8547739
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il10
interleukin 10
treatment
IDA IEP
associated with Constriction, Pathologic
RGD
PMID:22889616 PMID:22173123
RGD:7364826 , RGD:7364836
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1b
interleukin 1 beta
treatment
IEP
RGD
PMID:22173123
RGD:7364836
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
ISO
rat model treated with human protein
RGD
PMID:12574433
RGD:7175064
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il6
interleukin 6
IEP
protein:increased expression:dorsal root ganglion
RGD
PMID:20519054
RGD:5128675
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il6r
interleukin 6 receptor
IEP
protein:increased expression:dorsal root ganglion
RGD
PMID:20519054
RGD:5128675
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Jak1
Janus kinase 1
IEP
mRNA:increased expression:spinal cord
RGD
PMID:32012267
RGD:150527842
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
G
Jam3
junctional adhesion molecule 3
IEP
RGD
PMID:22950044
RGD:7488944
NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
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Kars1
lysyl-tRNA synthetase 1
IEP
mRNA,protein:decreased expression:dorsal root ganglion:
RGD
PMID:25467976
RGD:12910554
NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632
G
Kcnc4
potassium voltage-gated channel subfamily C member 4
IEP
RGD
PMID:17855600
RGD:10411908
NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:17108688
RGD:7297043
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
IEP
protein:decreased expression:spinal cord
RGD
PMID:21907492
RGD:12791994
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
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Lamp2
lysosomal-associated membrane protein 2
treatment
IEP
RGD
PMID:30015858
RGD:13703060
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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Lrp1
LDL receptor related protein 1
treatment
IEP ISO
RGD
PMID:26656067 PMID:18060043
RGD:13792690 , RGD:13800561
NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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Mag
myelin-associated glycoprotein
treatment
IDA
RGD
PMID:17705198
RGD:9685295
NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
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Map2
microtubule-associated protein 2
IEP
protein:decrease expression:dorsal root ganglion
RGD
PMID:21933624
RGD:6483083
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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Mc4r
melanocortin 4 receptor
IEP
protein:increased expression:dorsal root ganglia (rat)
RGD
PMID:21985621
RGD:6484557
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
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Mir21
microRNA 21
IEP
RNA:increased expression:dorsal root ganglion neuron
RGD
PMID:25484256
RGD:151893491
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir221
microRNA 221
IEP
RNA:increased expression:sciatic nerve:
RGD
PMID:22393241
RGD:11041067
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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Mir222
microRNA 222
IEP
RNA:increased expression:dorsal root ganglion neuron RNA:increased expression:sciatic nerve:
RGD
PMID:25484256 PMID:22393241
RGD:151893491 , RGD:11041067
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir381
microRNA 381
IEP
RNA:decreased expression:spinal cord
RGD
PMID:30142543
RGD:13838658
NCBI chr 6:128,740,976...128,741,036
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Mir96
microRNA 96
IEP
RNA:decreased expression:dorsal root ganglion:
RGD
PMID:24234845
RGD:11553932
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Mmp9
matrix metallopeptidase 9
treatment
IEP
RGD
PMID:25172308
RGD:13207330
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mpz
myelin protein zero
treatment
IEP
RGD
PMID:23545781
RGD:9685778
NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
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Mtor
mechanistic target of rapamycin kinase
IMP
RGD
PMID:20452291
RGD:10041037
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Myh4
myosin heavy chain 4
treatment
IEP
RGD
PMID:14973145
RGD:9686059
NCBI chr10:51,923,149...51,946,297
Ensembl chr10:51,885,913...51,946,295
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Nefh
neurofilament heavy chain
treatment
IEP
RGD
PMID:3135913 PMID:12445968
RGD:9693730 , RGD:9743941
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Nefl
neurofilament light chain
IEP
associated with Diabetes Mellitus, Type 1
RGD
PMID:12445968 PMID:3135913 PMID:12638730
RGD:9743941 , RGD:9693730 , RGD:9743948
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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Nefm
neurofilament medium chain
treatment
IEP
associated with Diabetes Mellitus, Type 1
RGD
PMID:12445968 PMID:3135913 PMID:12638730
RGD:9743941 , RGD:9693730 , RGD:9743948
NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
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Nf1
neurofibromin 1
IEP
protein:increased expression:sciatic nerve:
RGD
PMID:8847098
RGD:12790590
NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
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Nfkbia
NFKB inhibitor alpha
treatment
IDA
RGD
PMID:18938092
RGD:10413869
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Ngf
nerve growth factor
treatment
ISO
protein:increased expression:sciatic nerve
RGD
PMID:22776032 PMID:32652504
RGD:7242913 , RGD:401976543
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Ngfr
nerve growth factor receptor
ISO IEP
RGD
PMID:17576803 PMID:23138653
RGD:5144067 , RGD:10414078
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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Nlgn2
neuroligin 2
IEP
mRNA:decreased expression:sciatic nerve
RGD
PMID:17492651
RGD:9831149
NCBI chr10:54,544,461...54,557,854
Ensembl chr10:54,544,588...54,558,434
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Nlgn3
neuroligin 3
IEP
mRNA:decreased expression:sciatic nerve
RGD
PMID:17492651
RGD:9831149
NCBI chr X:66,427,926...66,457,378
Ensembl chr X:66,429,458...66,451,876
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Nmnat1
nicotinamide nucleotide adenylyltransferase 1
IEP
mRNA:increased expression:dorsal root ganglion:
RGD
PMID:16914673
RGD:13781948
NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
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Nos1ap
nitric oxide synthase 1 adaptor protein
IEP
mRNA:increased expression:sciatic nerve
RGD
PMID:17768032
RGD:7327169
NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949
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Nrg1
neuregulin 1
treatment
IMP
RGD
PMID:20957456
RGD:10449012
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Nts
neurotensin
IEP
RGD
PMID:8518953
RGD:9743903
NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
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Oprl1
opioid related nociceptin receptor 1
IEP
mRNA:increased expression:brain:
RGD
PMID:15862535
RGD:9835022
NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
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Oprm1
opioid receptor, mu 1
IEP
mRNA, protein:decreased expression:dorsal root ganglion
RGD
PMID:26917724 PMID:31836522
RGD:11531866 , RGD:401842373
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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Pcna
proliferating cell nuclear antigen
IEP
RGD
PMID:23014974
RGD:10448976
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pcsk5
proprotein convertase subtilisin/kexin type 5
IEP
mRNA,protein:increased expression:nerve:
RGD
PMID:9729404
RGD:11556234
NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600
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Pdgfra
platelet derived growth factor receptor alpha
IEP
RGD
PMID:19909480
RGD:11080976
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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Pdgfrb
platelet derived growth factor receptor beta
IEP
RGD
PMID:19909480
RGD:11080976
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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Plat
plasminogen activator, tissue type
IEP
RGD
PMID:18716863
RGD:6483827
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plau
plasminogen activator, urokinase
treatment
IEP IDA
mRNA:increased expression:sciatic nerve (rat)
RGD
PMID:18716863 PMID:21151668
RGD:6483827 , RGD:7241585
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Pmp22
peripheral myelin protein 22
IEP
RGD
PMID:1556154
RGD:1358785
NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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Ppargc1a
PPARG coactivator 1 alpha
IDA
associated with Diabetes Mellitus, Experimental
RGD
PMID:22996345
RGD:7242051
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Ptafr
platelet-activating factor receptor
IEP
mRNA:increased expression:spinal cord, microglia (rat)
RGD
PMID:22296727
RGD:9999207
NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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Ptn
pleiotrophin
IEP
mRNA:altered expression:dorsal root ganglia (rat)
RGD
PMID:18365878
RGD:9831453
NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
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Qars1
glutaminyl-tRNA synthetase 1
IEP
mRNA,protein:decreased expression:dorsal root ganglion:
RGD
PMID:25467976
RGD:12910554
NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
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Ran
RAN, member RAS oncogene family
IDA
RGD
PMID:18667152
RGD:9835000
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
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Ranbp1
RAN binding protein 1
IEP
protein:increased expression:sciatic nerve (rat)
RGD
PMID:18667152
RGD:9835000
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
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Rangap1
RAN GTPase activating protein 1
IEP
protein:increased expression:sciatic nerve, axon, cytoplasm (rat)
RGD
PMID:18667152
RGD:9835000
NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
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Rara
retinoic acid receptor, alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16782282
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rarb
retinoic acid receptor, beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16782282
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rchy1
ring finger and CHY zinc finger domain containing 1
IEP
protein:increased expression:sciatic nerve
RGD
PMID:21959983
RGD:10045367
NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167
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Reg3b
regenerating family member 3 beta
IEP
mRNA:increased expression:lumbar spinal cord, dorsal root ganglia (rat)
RGD
PMID:21561713
RGD:9831430
NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
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Rgma
repulsive guidance molecule BMP co-receptor a
IEP
RGD
PMID:16863689
RGD:9850145
NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
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Rpsa
ribosomal protein SA
IEP
RGD
PMID:19196078
RGD:11041651
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Runx1
RUNX family transcription factor 1
ISO
mRNA:decreased expression:dorsal root ganglion
RGD
PMID:22216140
RGD:6482827
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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Rxra
retinoid X receptor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16782282
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Scn10a
sodium voltage-gated channel alpha subunit 10
IMP
RGD
PMID:21965668
RGD:6484251
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
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Serpine1
serpin family E member 1
treatment
IDA
RGD
PMID:25967608
RGD:11075075
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpinf1
serpin family F member 1
treatment
ISO
human protein in a mouse model
RGD
PMID:10441236
RGD:8554886
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Slc17a7
solute carrier family 17 member 7
IEP
protein:decreased expression:nucleus accumbens
RGD
PMID:23835161
RGD:9999206
NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
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Slc17a8
solute carrier family 17 member 8
IEP
protein:decreased expression:nucleus accumbens
RGD
PMID:23835161
RGD:9999206
NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
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Snw1
SNW domain containing 1
IDA
protein:increased expression:sciatic nerve (rat)
RGD
PMID:23389663
RGD:11035242
NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
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Sod1
superoxide dismutase 1
severity treatment
ISO IDA
human gene in a rat model;DNA:missense mutation:cds:p.G93A (human)
RGD
PMID:21489258 PMID:15707675
RGD:8655638 , RGD:8655979
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Timp3
TIMP metallopeptidase inhibitor 3
IEP
RNA:decreased expression:dorsal root ganglion neuron
RGD
PMID:25484256
RGD:151893491
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Tlr2
toll-like receptor 2
ISO
mRNA:increased expression:sciatic nerve:
RGD
PMID:21125644
RGD:8553062
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
IEP ISO IMP
mRNA,protein:increased expression:spinal cord: mRNA:increased expression:spinal cord:
RGD
PMID:22173123 PMID:18615568 PMID:22173123
RGD:7364836 , RGD:7815041 , RGD:7364836
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnf
tumor necrosis factor
treatment
IEP
RGD
PMID:22173123
RGD:7364836
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO IEP
protein:increased expression:dorsal root ganglia (rat)
RGD
PMID:9582261 PMID:11240015
RGD:5130898 , RGD:5130963
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnfrsf1b
TNF receptor superfamily member 1B
IEP
protein:increased expression:dorsal root ganglia (rat)
RGD
PMID:11240015
RGD:5130963
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Bloc1s2
biogenesis of lysosomal organelles complex-1, subunit 2
IMP
RGD
PMID:16176350
RGD:2302154
NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
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Tnfrsf1b
TNF receptor superfamily member 1B
treatment
IDA
RGD
PMID:22425187
RGD:7245944
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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