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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:neuritis
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Accession:DOID:1803 term browser browse the term
Definition:A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
Synonyms:exact_synonym: Peripheral Neuritides;   Peripheral Neuritis;   Polyneuritides;   Polyneuritis;   Sensory Neuritides;   neuritides;   sensory neuritis
 primary_id: MESH:D009443
 alt_id: RDO:0006205
 xref: NCI:C116381
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
neuritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca4 ATP binding cassette subfamily A member 4 ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:8002831, PMID:9054934, PMID:9781034, PMID:9973280, PMID:10090887, PMID:10612508, PMID:10634594, PMID:10880298, PMID:11017087, PMID:11919200, PMID:11973624, PMID:12037008, PMID:12192456, PMID:12796258, PMID:14709597, PMID:15494742, PMID:15516930, PMID:16400609, PMID:16546111, PMID:18285826, PMID:18977788, PMID:19074458, PMID:19217903, PMID:19230850, PMID:20981092, PMID:22264887, PMID:23144455, PMID:23695285, PMID:24033266, PMID:24082139, PMID:24154662, PMID:24713488, PMID:25082885, PMID:25097241, PMID:25283059, PMID:25333069, PMID:25741868, PMID:26247787, PMID:27491360, PMID:28041643, PMID:28118664, PMID:28446513, PMID:28492532, PMID:30311386, PMID:30718709 NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:22539353, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 5:21,769,087...21,952,036
Ensembl chr 5:21,830,882...21,950,696
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:25741868, PMID:26752647 NCBI chr 9:94,302,218...94,308,591 JBrowse link
G Dysf dysferlin ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:25741868, PMID:28492532 NCBI chr 4:115,700,942...115,901,873
Ensembl chr 4:115,712,850...115,901,873
JBrowse link
G Iars2 isoleucyl-tRNA synthetase 2, mitochondrial ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:8409271, PMID:25130867 NCBI chr13:103,229,868...103,265,019
Ensembl chr13:103,231,387...103,264,906
JBrowse link
G Lmna lamin A/C ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:19589617, PMID:22918509, PMID:23183350, PMID:24033266, PMID:25741868, PMID:26332594, PMID:27919367, PMID:28074886, PMID:28255936, PMID:28492532, PMID:28663758, PMID:29791652 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Mybpc3 myosin binding protein C3 ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:22958901, PMID:24793961, PMID:25741868, PMID:27532257, PMID:28492532 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Nefl neurofilament light ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:12481988, PMID:15111691, PMID:16452125, PMID:19286384, PMID:21168446, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Tgm6 transglutaminase 6 ISO ClinVar Annotator: match by term: Peripheral neuritis ClinVar PMID:25741868, PMID:30311386 NCBI chr 3:122,644,183...122,680,054
Ensembl chr 3:122,662,086...122,679,128
JBrowse link
brachial plexus neuritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Septin9 septin 9 ISO hereditary neuralgic amyotrophy, OMIM:604061
ClinVar Annotator: match by term: Hereditary Neuralgic Amyotrophy (HNA)
ClinVar Annotator: match by term: Hereditary neuralgic amyotrophy
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:162100
ClinVar
CTD
OMIM
PMID:16186812, PMID:17546647, PMID:18492087, PMID:19139049, PMID:19204161, PMID:19451530, PMID:20019224, PMID:22981636, PMID:25741868, PMID:26467025, PMID:28492532, PMID:16186812 RGD:1599349 NCBI chr10:106,208,308...106,340,747
Ensembl chr10:106,264,434...106,348,490
JBrowse link
carpal tunnel syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttr transthyretin ISO ClinVar Annotator: match by term: Carpal tunnel syndrome
ClinVar Annotator: match by term: AMYOTROPHY, THENAR, OF CARPAL ORIGIN
ClinVar Annotator: match by term: Carpal tunnel syndrome, familial
OMIM
ClinVar
PMID:192115, PMID:1351039, PMID:1353008, PMID:1358785, PMID:1490495, PMID:1547960, PMID:1570831, PMID:1867256, PMID:1977686, PMID:1992765, PMID:1997217, PMID:2002274, PMID:2046936, PMID:2063870, PMID:2237288, PMID:2320592, PMID:2349941, PMID:2564060, PMID:2590199, PMID:2624269, PMID:2646319, PMID:2714785, PMID:2856994, PMID:2857043, PMID:2896079, PMID:3011930, PMID:3022107, PMID:3022108, PMID:3022697, PMID:3030336, PMID:3229002, PMID:3457802, PMID:3479441, PMID:3627183, PMID:3908483, PMID:3934968, PMID:4079954, PMID:4138132, PMID:4354899, PMID:5507249, PMID:5652991, PMID:5799493, PMID:6087811, PMID:6100724, PMID:6208668, PMID:6311926, PMID:6549130, PMID:6583672, PMID:6651852, PMID:6736244, PMID:6782125, PMID:7389759, PMID:7839813, PMID:7868124, PMID:8064809, PMID:8100581, PMID:8194279, PMID:8309582, PMID:8563114, PMID:8698351, PMID:8721565, PMID:8778271, PMID:8857732, PMID:9017939, PMID:9215058, PMID:9475090, PMID:10453736, PMID:10465115, PMID:10488818, PMID:10506096, PMID:10529370, PMID:10762172, PMID:10842715, PMID:11385707, PMID:11709003, PMID:11752419, PMID:11752443, PMID:11940682, PMID:12050338, PMID:12217248, PMID:12433265, PMID:12566023, PMID:12617705, PMID:12874413, PMID:12874414, PMID:14569203, PMID:14640030, PMID:14673473, PMID:14986482, PMID:15123043, PMID:15185492, PMID:15249622, PMID:15299606, PMID:15523922, PMID:15820680, PMID:15930086, PMID:16011990, PMID:16194874, PMID:16194875, PMID:16432141, PMID:16631014, PMID:16631015, PMID:17251346, PMID:17503405, PMID:17698792, PMID:18276611, PMID:18318779, PMID:18460047, PMID:18606975, PMID:18830126, PMID:18863976, PMID:18925456, PMID:19364362, PMID:19602727, PMID:19709674, PMID:19781421, PMID:19808383, PMID:20209591, PMID:20301373, PMID:20435197, PMID:21600538, PMID:22083004, PMID:22184092, PMID:22382560, PMID:22531659, PMID:22592564, PMID:22620962, PMID:22745357, PMID:22877808, PMID:22995991, PMID:23080516, PMID:23279339, PMID:23387326, PMID:23414091, PMID:23713495, PMID:23716704, PMID:23833285, PMID:23993291, PMID:24046394, PMID:24073013, PMID:24164154, PMID:24184229, PMID:24455802, PMID:24474780, PMID:24517438, PMID:24555660, PMID:24601850, PMID:24633258, PMID:24800914, PMID:24818650, PMID:24945718, PMID:25225131, PMID:25395306, PMID:25550818, PMID:25551524, PMID:25741868, PMID:25819286, PMID:25846356, PMID:26115788, PMID:26123279, PMID:26428663, PMID:26467025, PMID:26537620, PMID:27793437, PMID:28492532, PMID:28635949, PMID:29121657 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
Experimental Autoimmune Neuritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 ISO RGD PMID:9670863 RGD:2325244 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:spinal cord (rat) RGD PMID:15710454 RGD:2313042 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Anxa1 annexin A1 IEP protein:increased expression:sciatic nerve RGD PMID:10603033 RGD:2306914 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G App amyloid beta precursor protein treatment IDA RGD PMID:28446186 RGD:13782060 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cav1 caveolin 1 IEP protein:increased phosphorylation:sciatic nerve RGD PMID:17234162 RGD:2289125 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO protein:increased expression:sciatic nerve, macrophage, T cell RGD PMID:20500551 RGD:5688140 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd14 CD14 molecule severity IEP RGD PMID:19162137 RGD:2312712 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd28 Cd28 molecule IMP RGD PMID:12864982 RGD:2307204 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd40 CD40 molecule IEP RGD PMID:17188497 RGD:5491181 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand IEP RGD PMID:17188497 RGD:5491181 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd59 CD59 molecule IEP protein:increased expression:Schwann cell RGD PMID:10450801 RGD:1600494 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP RGD PMID:18448252 RGD:4891968 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP RGD PMID:18448252 RGD:4891968 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Dcc DCC netrin 1 receptor IEP RGD PMID:16337279 RGD:2314374 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) treatment IMP RGD PMID:11522581 RGD:11040446 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:23603807 RGD:10395381 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epo erythropoietin IEP RGD PMID:20361946 RGD:10400894 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Foxp3 forkhead box P3 IEP protein:decreased expression:sciatic nerve RGD PMID:30464413 RGD:38549576 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 disease_progression IEP mRNA,protein:increased expression:sciatic nerve: RGD PMID:21784136 RGD:9686114 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP RGD PMID:23603807 RGD:10395381 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression IMP RGD PMID:17286627 RGD:5508466 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Il17a interleukin 17A ISO
IEP
mRNA, protein:increased expression:sciatic nerve, inguinal lymph node RGD PMID:10785455, PMID:19207263 RGD:4888513, RGD:4831923 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:18400050 RGD:7401218 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il5 interleukin 5 treatment IDA RGD PMID:22310911 RGD:11522768 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP RGD PMID:9546322 RGD:9685357 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:9546322 RGD:9685357 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nos2 nitric oxide synthase 2 IEP protein:increased expression:nerve root, leukocyte, Schwann cell (rat) RGD PMID:15144861 RGD:1580265 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP protein:increased expression: RGD PMID:12916703 RGD:5688236 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP protein:increased expression: RGD PMID:12916703 RGD:5688236 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rhoa ras homolog family member A IEP protein:increased expression:spinal ganglion, macrophage, T cell RGD PMID:17367505 RGD:1642966 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:15531104 RGD:1581323 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tlr2 toll-like receptor 2 severity IEP RGD PMID:19162137 RGD:2312712 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA:increased expression:multiple tissues RGD PMID:18434754 RGD:2312677 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr9 toll-like receptor 9 IEP mRNA:increased expression:multiple tissues RGD PMID:18434754 RGD:2312677 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:18400050 RGD:7401218 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
lesion of sciatic nerve term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag1 BAG cochaperone 1 IEP RGD PMID:23108487 RGD:13506903 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Rgs3 regulator of G-protein signaling 3 IEP mRNA:decreased expression:dorsal root ganglion RGD PMID:14550772 RGD:13524539 NCBI chr 5:78,429,017...78,567,281
Ensembl chr 5:78,428,669...78,567,288
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IEP mRNA:decreased expression:dorsal root ganglion RGD PMID:14550772 RGD:13524539 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
median neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:19296522 RGD:10449020 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 IEP RGD PMID:19296522 RGD:10449020 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEP RGD PMID:19296522 RGD:10449020 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Mt1 metallothionein 1 IEP RGD PMID:22253198 RGD:6483815 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A IEP mRNA:decreased expression:left median nerve (rat) RGD PMID:22253198 RGD:6483815 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 treatment IEP RGD PMID:22253198 RGD:6483815 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Npy neuropeptide Y IEP RGD PMID:19456245 RGD:10448955 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nrg1 neuregulin 1 IEP RGD PMID:19296522 RGD:10449020 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 ISO ClinVar Annotator: match by term: Mononeuropathy of the Median Nerve ClinVar PMID:25741868, PMID:26467025, PMID:28492532 NCBI chr18:57,286,266...57,403,926
Ensembl chr18:57,286,322...57,347,577
JBrowse link
motor neuritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmna lamin A/C ISO ClinVar Annotator: match by term: Peripheral motor neuropathy ClinVar PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO ClinVar Annotator: match by term: Peripheral motor neuropathy ClinVar PMID:28492532, PMID:30311386 NCBI chr 1:41,608,287...41,763,591
NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
JBrowse link
sciatic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IEP protein:decreased expression:spinal cord RGD PMID:21907492 RGD:12791994 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 IEP protein:decreased expression:spinal cord RGD PMID:21907492 RGD:12791994 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Adrb2 adrenoceptor beta 2 treatment ISO RGD PMID:19912227 RGD:8548489 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen IDA RGD PMID:20886512 RGD:5129198 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP mRNA,protein:increased expression:spinal cord: RGD PMID:19937403 RGD:14348968 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 IEP protein:increased expression:dorsal root ganglion (rat) RGD PMID:23613963 RGD:14390159 NCBI chr 8:116,830,773...116,832,299 JBrowse link
G Apoa1 apolipoprotein A1 IEP protein:increased expression:sciatic nerve: RGD PMID:2493483 RGD:7495790 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:sciatic nerve: RGD PMID:2493483 RGD:7495790 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP RGD PMID:18182225 RGD:5129227 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP RGD PMID:18182225 RGD:5129227 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP
IDA
protein:increased expression:dorsal root ganglion: RGD PMID:22309829, PMID:24388817 RGD:8657100, RGD:10059363 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G C3 complement C3 IEP protein:increased expression:sciatic nerve RGD PMID:18052971 RGD:5129535 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEP mRNA:decreased expression:spinal cord dorsal horn RGD PMID:16026470 RGD:6906922 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IEP mRNA:increased expression:dorsal root ganglion RGD PMID:22972512 RGD:15042903 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IEP mRNA:increased expression:dorsal root ganglion RGD PMID:22972512 RGD:15042903 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO CTD Direct Evidence: therapeutic CTD PMID:19852068 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Capn1 calpain 1 IEP protein:increased expression:skeletal muscle tissue of tibialis anterior RGD PMID:24745757 RGD:13792589 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 IEP protein:increased expression:skeletal muscle tissue of tibialis anterior RGD PMID:24745757 RGD:13792589 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Casp12 caspase 12 IDA mRNA, protein:increased expression:dorsal root ganglion RGD PMID:29659443 RGD:13782273 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 IEP mRNA:increased expression:dorsal root ganglion RGD PMID:29659443 RGD:13782273 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 IEP mRNA:increased expression:dorsal root ganglion RGD PMID:29659443 RGD:13782273 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 IEP mRNA:increased expression:dorsal root ganglion RGD PMID:29659443 RGD:13782273 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase IEP protein:decreased activity:sciatic nerve, spinal cord, dorsal root ganglion: RGD PMID:19675389 RGD:9479064 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 IEP protein:decreased expression:spinal cord, blood vessel RGD PMID:21795534 RGD:6784526 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:spinal cord dorsal horn, axon terminal (rat)
protein:increased expression:lumbar dorsal root ganglion (mouse)
RGD PMID:19059387, PMID:22564672 RGD:2307005, RGD:8549487 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:sciatic nerve (rat) RGD PMID:19152028 RGD:4890004 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:24907405 RGD:8661781
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP protein:decreased expression:sciatic nerve RGD PMID:21959983 RGD:10045367 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cnr2 cannabinoid receptor 2 treatment IDA RGD PMID:19345493 RGD:2316195 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Crcp CGRP receptor component IEP RGD PMID:12895509 RGD:727768 NCBI chr12:30,125,237...30,160,857
Ensembl chr12:30,125,168...30,180,115
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IEP protein:increased phosphorylation:nucleus RGD PMID:19918364 RGD:10059430 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:central nucleus of amygdala, bed nucleus of stria terminalis (rat) RGD PMID:21684787 RGD:5490542 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 treatment ISO
IEP
RGD PMID:20524966, PMID:15341587, PMID:20921832 RGD:9354422, RGD:1358720, RGD:9491396 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:16632873 RGD:4889134 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP mRNA:decreased expression:spinal cord (rat) RGD PMID:17720801 RGD:4889112 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Dbn1 drebrin 1 IEP protein:increased expression:neuron: RGD PMID:11578820 RGD:10398813 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO protein:increased expression:brain: RGD PMID:22031875 RGD:9589072 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Elavl4 ELAV like RNA binding protein 4 IEP RGD PMID:12957493 RGD:1579851 NCBI chr 5:130,001,387...130,144,557
Ensembl chr 5:130,001,372...130,085,838
JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:29970988 RGD:13792563 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP mRNA:increased expression:neuron: RGD PMID:8971765 RGD:10402092 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fubp1 far upstream element binding protein 1 IEP RGD PMID:23939805 RGD:13673880 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Gc GC, vitamin D binding protein ISO protein:increased expression:nerve RGD PMID:15509515 RGD:2316214 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP mRNA:increased expression:sciatic nerve RGD PMID:10852218 RGD:6218977 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfra1 GDNF family receptor alpha 1 IEP protein:increased expression:spinal cord dorsal horn RGD PMID:20533358 RGD:6218963 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gfra3 GDNF family receptor alpha 3 IEP mRNA:increased expression:sciatic nerve RGD PMID:10852218 RGD:6218977 NCBI chr18:27,491,860...27,520,133
Ensembl chr18:27,491,845...27,520,295
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 IEP RGD PMID:26656067 RGD:13792690 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP RGD PMID:26656067 RGD:13792690 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IDA RGD PMID:27125978 RGD:13792740 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hgf hepatocyte growth factor treatment ISO RGD PMID:18941443 RGD:8548631 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:23991202 RGD:10402062 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IDA RGD PMID:23224421 RGD:10755722 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:17350523 RGD:1626418 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP mRNA:increased expression:fourth lumbar dorsal root ganglion (rat) RGD PMID:12648755 RGD:632873
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:20546684 RGD:8547739 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 treatment IDA
IEP
associated with Constriction, Pathologic RGD PMID:22889616, PMID:22173123 RGD:7364826, RGD:7364836 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:22173123 RGD:7364836 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:12574433 RGD:7175064 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:dorsal root ganglion RGD PMID:20519054 RGD:5128675 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor IEP protein:increased expression:dorsal root ganglion RGD PMID:20519054 RGD:5128675 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Jam3 junctional adhesion molecule 3 IEP RGD PMID:22950044 RGD:7488944 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466
JBrowse link
G Kars lysyl-tRNA synthetase IEP mRNA,protein:decreased expression:dorsal root ganglion: RGD PMID:25467976 RGD:12910554 NCBI chr19:44,212,205...44,231,209
Ensembl chr19:44,212,206...44,231,157
JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IEP RGD PMID:17855600 RGD:10411908 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP mRNA:increased expression:dorsal root ganglion RGD PMID:17108688 RGD:7297043 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IEP protein:decreased expression:spinal cord RGD PMID:21907492 RGD:12791994 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 treatment IEP RGD PMID:30015858 RGD:13703060 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lrp1 LDL receptor related protein 1 treatment IEP
ISO
RGD PMID:26656067, PMID:18060043 RGD:13792690, RGD:13800561 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Mag myelin-associated glycoprotein treatment IDA RGD PMID:17705198 RGD:9685295 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Map2 microtubule-associated protein 2 IEP protein:decrease expression:dorsal root ganglion RGD PMID:21933624 RGD:6483083 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mc4r melanocortin 4 receptor IEP protein:increased expression:dorsal root ganglia (rat) RGD PMID:21985621 RGD:6484557 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725
JBrowse link
G Mir381 microRNA 381 IEP RNA:decreased expression:spinal cord RGD PMID:30142543 RGD:13838658 NCBI chr 6:133,876,615...133,876,675
Ensembl chr 6:133,876,586...133,876,693
JBrowse link
G Mir96 microRNA 96 IEP RNA:decreased expression:dorsal root ganglion: RGD PMID:24234845 RGD:11553932 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP RGD PMID:25172308 RGD:13207330 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpz myelin protein zero treatment IEP RGD PMID:23545781 RGD:9685778 NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:20452291 RGD:10041037 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myh4 myosin heavy chain 4 treatment IEP RGD PMID:14973145 RGD:9686059 NCBI chr10:53,778,456...53,801,605
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Nefh neurofilament heavy treatment IEP RGD PMID:3135913, PMID:12445968 RGD:9693730, RGD:9743941 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light IEP associated with Diabetes Mellitus, Type 1 RGD PMID:12445968, PMID:12638730 RGD:9743941, RGD:9743948 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium treatment IEP associated with Diabetes Mellitus, Type 1 RGD PMID:12445968, PMID:12638730 RGD:9743941, RGD:9743948 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nf1 neurofibromin 1 IEP protein:increased expression:sciatic nerve: RGD PMID:8847098 RGD:12790590 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IDA RGD PMID:18938092 RGD:10413869 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor treatment ISO RGD PMID:22776032 RGD:7242913 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor ISO
IEP
RGD PMID:17576803, PMID:23138653 RGD:5144067, RGD:10414078 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nlgn2 neuroligin 2 IEP mRNA:decreased expression:sciatic nerve RGD PMID:17492651 RGD:9831149 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847
JBrowse link
G Nlgn3 neuroligin 3 IEP mRNA:decreased expression:sciatic nerve RGD PMID:17492651 RGD:9831149 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IEP mRNA:increased expression:dorsal root ganglion: RGD PMID:16914673 RGD:13781948 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein IEP mRNA:increased expression:sciatic nerve RGD PMID:17768032 RGD:7327169 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Nrg1 neuregulin 1 treatment IMP RGD PMID:20957456 RGD:10449012 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nts neurotensin IEP RGD PMID:8518953 RGD:9743903 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IEP mRNA:increased expression:brain: RGD PMID:15862535 RGD:9835022 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Pcna proliferating cell nuclear antigen IEP RGD PMID:23014974 RGD:10448976 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 IEP mRNA,protein:increased expression:nerve: RGD PMID:9729404 RGD:11556234 NCBI chr 1:236,031,988...236,313,858
Ensembl chr 1:236,031,988...236,313,858
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:19909480 RGD:11080976 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:19909480 RGD:11080976 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plat plasminogen activator, tissue type IEP RGD PMID:18716863 RGD:6483827 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase treatment IEP
IDA
mRNA:increased expression:sciatic nerve (rat) RGD PMID:18716863, PMID:21151668 RGD:6483827, RGD:7241585 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pmp22 peripheral myelin protein 22 IEP RGD PMID:1556154 RGD:1358785 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IDA associated with Diabetes Mellitus, Experimental RGD PMID:22996345 RGD:7242051 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ptafr platelet-activating factor receptor IEP mRNA:increased expression:spinal cord, microglia (rat) RGD PMID:22296727 RGD:9999207 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptn pleiotrophin IEP mRNA:altered expression:dorsal root ganglia (rat) RGD PMID:18365878 RGD:9831453 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 IEP mRNA,protein:decreased expression:dorsal root ganglion: RGD PMID:25467976 RGD:12910554 NCBI chr 8:117,297,670...117,305,708
Ensembl chr 8:117,297,670...117,305,702
JBrowse link
G Ran RAN, member RAS oncogene family IDA RGD PMID:18667152 RGD:9835000 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Ranbp1 RAN binding protein 1 IEP protein:increased expression:sciatic nerve (rat) RGD PMID:18667152 RGD:9835000 NCBI chr11:86,890,585...86,898,818
Ensembl chr11:86,890,585...86,898,818
JBrowse link
G Rangap1 RAN GTPase activating protein 1 IEP protein:increased expression:sciatic nerve, axon, cytoplasm (rat) RGD PMID:18667152 RGD:9835000 NCBI chr 7:122,939,266...122,967,178
Ensembl chr 7:122,940,376...122,967,178
JBrowse link
G Rara retinoic acid receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782282 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782282 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 IEP protein:increased expression:sciatic nerve RGD PMID:21959983 RGD:10045367 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Reg3b regenerating family member 3 beta IEP mRNA:increased expression:lumbar spinal cord, dorsal root ganglia (rat) RGD PMID:21561713 RGD:9831430 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IEP RGD PMID:16863689 RGD:9850145 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rpsa ribosomal protein SA IEP RGD PMID:19196078 RGD:11041651 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Runx1 RUNX family transcription factor 1 ISO mRNA:decreased expression:dorsal root ganglion RGD PMID:22216140 RGD:6482827 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Rxra retinoid X receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782282 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 IMP RGD PMID:21965668 RGD:6484251 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:25967608 RGD:11075075 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO human protein in a mouse model RGD PMID:10441236 RGD:8554886 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Slc17a7 solute carrier family 17 member 7 IEP protein:decreased expression:nucleus accumbens RGD PMID:23835161 RGD:9999206 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP protein:decreased expression:nucleus accumbens RGD PMID:23835161 RGD:9999206 NCBI chr 7:30,215,231...30,274,993
Ensembl chr 7:30,216,104...30,274,984
JBrowse link
G Snw1 SNW domain containing 1 IDA protein:increased expression:sciatic nerve (rat) RGD PMID:23389663 RGD:11035242 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sod1 superoxide dismutase 1 severity
treatment
ISO
IDA
human gene in a rat model;DNA:missense mutation:cds:p.G93A (human) RGD PMID:21489258, PMID:15707675 RGD:8655638, RGD:8655979 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA:increased expression:sciatic nerve: RGD PMID:21125644 RGD:8553062 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO
IMP
mRNA,protein:increased expression:spinal cord:
mRNA:increased expression:spinal cord:
RGD PMID:22173123, PMID:18615568, PMID:22173123 RGD:7364836, RGD:7815041, RGD:7364836 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:22173123 RGD:7364836 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO
IEP
protein:increased expression:dorsal root ganglia (rat) RGD PMID:9582261, PMID:11240015 RGD:5130898, RGD:5130963 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP protein:increased expression:dorsal root ganglia (rat) RGD PMID:11240015 RGD:5130963 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
Sciatica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 IMP RGD PMID:16176350 RGD:2302154 NCBI chr 1:263,913,901...263,920,989
Ensembl chr 1:263,913,854...263,920,962
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B treatment IDA RGD PMID:22425187 RGD:7245944 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        peripheral nervous system disease 2500
          neuritis 192
            Experimental Autoimmune Neuritis 51
            brachial plexus neuritis + 1
            mononeuritis + 138
            motor neuritis + 2
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        peripheral nervous system disease 2500
          neuropathy 2320
            neuritis 192
              Experimental Autoimmune Neuritis 51
              brachial plexus neuritis + 1
              mononeuritis + 138
              motor neuritis + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.