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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:pancreatic cancer
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Accession:DOID:1793 term browser browse the term
Definition:An endocrine gland cancer located_in the pancreas. (DO)
Synonyms:exact_synonym: Ca body of pancreas;   Ca head of pancreas;   Ca tail of pancreas;   cancer of pancreas;   cancer of the pancreas;   malignant neoplasm of body of pancreas;   malignant neoplasm of head of pancreas;   malignant neoplasm of tail of pancreas;   pancreas cancer;   pancreas cancers;   pancreatic cancer 3;   pancreatic cancers;   pancreatic tumor
 related_synonym: PNCA1;   PNCA2;   PNCA3;   PNCA4;   PNCA5;   pancreatic cancer, susceptibility to, 1;   pancreatic cancer, susceptibility to, 2;   pancreatic cancer, susceptibility to, 3;   pancreatic cancer, susceptibility to, 4;   pancreatic cancer, susceptibility to, 5
 primary_id: MESH:D010190
 alt_id: OMIM:260350;   OMIM:606856;   OMIM:613347;   OMIM:613348;   OMIM:614320;   OMIM:618680
 xref: GARD:9364;   ICD10CM:C25.0;   ICD10CM:C25.1;   ICD10CM:C25.2;   ICD9CM:157.0;   ICD9CM:157.1;   ICD9CM:157.2;   ICD9CM:157.8;   NCI:C3305;   ORDO:1333;   ORDO:217074
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
pancreatic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4gnt alpha-1,4-N-acetylglucosaminyltransferase ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:16441422 RGD:2325199 NCBI chr 8:107,856,853...107,866,438
Ensembl chr 8:107,859,366...107,865,789
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO mRNA, protein:increased expression:pancreas RGD PMID:19020751 RGD:2317509 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 severity ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648918 PMID:26098869, PMID:20103627 RGD:2317511 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme ISO RGD PMID:19880966 RGD:2325208 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acvr1 activin A receptor type 1 ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Acvr1b activin A receptor type 1B ISO mRNA:increased expression:pancreas RGD PMID:9714055, PMID:11248065 RGD:2317217, RGD:1598735 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Acvr2a activin A receptor type 2A ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 ISO protein:increased expression:pancreas RGD PMID:12428789 RGD:2317573 NCBI chr19:24,854,981...24,875,712
Ensembl chr19:24,855,299...24,875,137
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) ISO DNA:polymorphism: :p.R272Q (human) RGD PMID:19068087 RGD:2325313 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adm adrenomedullin disease_progression ISO RGD PMID:17363587, PMID:16841081 RGD:2325317, RGD:2325318 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:serum RGD PMID:20398646 RGD:2325643 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA:increased expression:pancreas RGD PMID:11916627 RGD:2325641 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Ahr aryl hydrocarbon receptor ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:12203118 PMID:25826687, PMID:12203118 RGD:2325664 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity
treatment
ISO protein:increased phosphorylation:pancreas (human)
human cells in a mouse model
RGD PMID:20697673, PMID:11595724 RGD:13450953, RGD:13452388 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:16847462, PMID:19506583 RGD:2290476, RGD:5490965 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:18154768, PMID:20508721 RGD:2325678, RGD:2325675 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO protein:decreased expression:pancreas RGD PMID:19216797 RGD:2325688 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:polymorphism: :p.E504K (human)
DNA:polymorphism (human)
RGD PMID:19068087, PMID:15714130 RGD:2325313, RGD:2325694 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO protein:increased expression:pancreas RGD PMID:12163367, PMID:12481414 RGD:2317524, RGD:2317523 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ang angiogenin disease_progression ISO mRNA, protein:increased expression:pancreas, serum RGD PMID:8665497 RGD:2325716 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:pancreas RGD PMID:19173988, PMID:17974280 RGD:2325722, RGD:2325723 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa10 annexin A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:increased expression:pancreas RGD PMID:17224646 RGD:2325739 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO DNA:deletions (human)
DNA:mutation, loss of heterozygosity
RGD PMID:1423316, PMID:7478622 RGD:2317208, RGD:2317207 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apoa1 apolipoprotein A1 ISO protein:decreased expression:serum
protein:increased expression:pancreas
RGD PMID:17312459, PMID:17332923 RGD:2325758, RGD:2325757 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:pancreas RGD PMID:16215274 RGD:2317552 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arid1a AT-rich interaction domain 1A ISO RGD PMID:23355908 RGD:8694154 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636
JBrowse link
G Arid1b AT-rich interaction domain 1B ISO RGD PMID:23355908 RGD:8694154 NCBI chr 1:45,923,119...46,232,301
Ensembl chr 1:45,923,222...46,234,874
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO DNA:amplification (human) RGD PMID:19145645 RGD:2317557 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058
JBrowse link
G Artn artemin disease_progression ISO mRNA:increased expression:pancreas RGD PMID:20395845, PMID:19304517 RGD:2325815, RGD:2325817 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986
JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:rs664677 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:rs1801516(human)
DNA:SNP: :60G>A(human)
CTD PMID:26098866 PMID:26098869, PMID:16520463, PMID:19147782, PMID:18381943 RGD:2317367, RGD:2317363, RGD:2317234 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase ISO DNA:SNP: :340C>T (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atrx ATRX, chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 ISO mRNA:increased expression:pancreas RGD PMID:14555842 RGD:2317558 NCBI chr11:36,638,067...36,683,915
Ensembl chr11:36,634,662...36,683,672
JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO human cells in a mouse model RGD PMID:23523869 RGD:13451129 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag3 BAG cochaperone 3 ISO mRNA:increased expression:pancreas RGD PMID:11513873 RGD:2325843 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bag4 BAG cochaperone 4 ISO mRNA:increased expression:pancreas RGD PMID:10799310 RGD:2325852 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320
JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bcl2l1 Bcl2-like 1 severity ISO human gene in a mouse model
CTD Direct Evidence: marker/mechanism
CTD PMID:16904634, PMID:17941720 RGD:11353794 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:15943879 RGD:2317560 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:61,084,216...61,159,220
Ensembl chr11:61,083,757...61,158,838
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase disease_progression ISO human gene in a mouse model RGD PMID:18490924, PMID:22628411, PMID:22871572 RGD:13451537, RGD:13462040, RGD:13461863 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Brca1 BRCA1, DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Cancer of the pancreas
CTD
ClinVar
OMIM
PMID:7795652 PMID:7837387 PMID:7894493 PMID:8644702 PMID:8723683 PMID:8968102 PMID:9159158 PMID:9510469 PMID:9525870 PMID:9663595 PMID:10389907 PMID:10788334 PMID:10945975 PMID:11278247 PMID:11320250 PMID:11389159 PMID:11504767 PMID:12204006 PMID:12393792 PMID:12566964 PMID:12601471 PMID:12732733 PMID:12810666 PMID:12938098 PMID:14976165 PMID:15024741 PMID:15235020 PMID:15290653 PMID:15365993 PMID:15383404 PMID:15385441 PMID:15569676 PMID:15876480 PMID:16168118 PMID:16227521 PMID:16267036 PMID:16403807 PMID:16949048 PMID:17100994 PMID:18273839 PMID:18680205 PMID:18763032 PMID:18783588 PMID:19208665 PMID:19370767 PMID:19543972 PMID:19594371 PMID:19770520 PMID:19996028 PMID:20103620 PMID:20104584 PMID:20180014 PMID:20345474 PMID:20373018 PMID:20507347 PMID:20569256 PMID:20683152 PMID:21232165 PMID:21324516 PMID:21503673 PMID:21520273 PMID:21922593 PMID:21965345 PMID:21989927 PMID:21990134 PMID:21990165 PMID:22172724 PMID:22486713 PMID:22713736 PMID:22798144 PMID:22843421 PMID:23161852 PMID:23199084 PMID:23469205 PMID:23683081 PMID:23867111 PMID:24033266 PMID:24131973 PMID:24312913 PMID:24504028 PMID:24884479 PMID:25330149 PMID:25400221 PMID:25525159 PMID:25637381 PMID:25682074 PMID:25741868 PMID:25782689 PMID:25802882 PMID:25823446 PMID:25948282 PMID:26083025 PMID:26098869 PMID:26187060 PMID:26206375 PMID:26219728 PMID:26295337 PMID:26332594 PMID:26350514 PMID:26467025 PMID:26681312 PMID:26852130 PMID:27153395 PMID:27272900 PMID:27425403 PMID:27433846 PMID:27498913 PMID:27741520 PMID:27907908 PMID:27978560 PMID:28111427 PMID:28263838 PMID:28324225 PMID:28364669 PMID:28423363 PMID:28477318 PMID:28480178 PMID:28492532 PMID:28781887 PMID:29335924 PMID:29433453 PMID:29492181 PMID:29797126 PMID:29998185 PMID:30067863 PMID:30209399 PMID:30606148 PMID:32295079 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated susceptibility ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: Cancer of the pancreas
CTD Direct Evidence: marker/mechanism
DNA:mutations: :
OMIM
ClinVar
CTD
PMID:8075631 PMID:8524414 PMID:8673090 PMID:8673091 PMID:8673092 PMID:8758903 PMID:8841191 PMID:8841192 PMID:8896551 PMID:8988179 PMID:9042909 PMID:9145676 PMID:9150172 PMID:9667259 PMID:9758598 PMID:9792861 PMID:9971877 PMID:10417300 PMID:10570174 PMID:10644434 PMID:11149425 PMID:11179017 PMID:11307153 PMID:11595708 PMID:11802209 PMID:11948123 PMID:12142080 PMID:12473589 PMID:12670525 PMID:14559878 PMID:14576434 PMID:14647438 PMID:14973102 PMID:15070707 PMID:15117986 PMID:15131399 PMID:15145354 PMID:15168169 PMID:15340362 PMID:15382066 PMID:15695382 PMID:15994883 PMID:16168118 PMID:16683254 PMID:16825431 PMID:16949048 PMID:17063270 PMID:17100994 PMID:17148771 PMID:17591843 PMID:17657584 PMID:17688236 PMID:17899372 PMID:17972171 PMID:17972177 PMID:18042939 PMID:18489799 PMID:18607349 PMID:18627636 PMID:18779604 PMID:19016756 PMID:19043619 PMID:19188187 PMID:19471317 PMID:19491284 PMID:19499246 PMID:19654294 PMID:19656164 PMID:19863560 PMID:20104584 PMID:20167696 PMID:20215541 PMID:20216074 PMID:20301425 PMID:20380699 PMID:20694749 PMID:20736950 PMID:20858050 PMID:20887823 PMID:21120943 PMID:21205087 PMID:21218378 PMID:21324516 PMID:21613821 PMID:21709188 PMID:21913181 PMID:21952622 PMID:22006311 PMID:22009639 PMID:22126563 PMID:22217648 PMID:22430266 PMID:22703879 PMID:22762150 PMID:22970155 PMID:22995991 PMID:23199084 PMID:23265383 PMID:23318356 PMID:23341105 PMID:23415752 PMID:23469205 PMID:23569316 PMID:23621881 PMID:23658460 PMID:24033266 PMID:24055113 PMID:24156927 PMID:24470074 PMID:24489791 PMID:24728189 PMID:24728327 PMID:24830819 PMID:24884479 PMID:25085752 PMID:25136594 PMID:25186627 PMID:25452441 PMID:25525159 PMID:25637381 PMID:25682074 PMID:25737278 PMID:25741868 PMID:25782689 PMID:25802882 PMID:25863477 PMID:25980754 PMID:26026974 PMID:26098869 PMID:26187060 PMID:26221963 PMID:26295337 PMID:26360800 PMID:26402875 PMID:26440929 PMID:26467025 PMID:26530882 PMID:26541979 PMID:26681312 PMID:26709275 PMID:26757417 PMID:26852015 PMID:26867194 PMID:27124784 PMID:27157322 PMID:27257965 PMID:27376475 PMID:27425403 PMID:27658390 PMID:27701467 PMID:27732944 PMID:27741520 PMID:27882536 PMID:27907908 PMID:28008555 PMID:28111427 PMID:28179634 PMID:28222693 PMID:28277317 PMID:28283652 PMID:28294317 PMID:28324225 PMID:28351343 PMID:28419251 PMID:28492532 PMID:28541631 PMID:28616458 PMID:28724667 PMID:28767289 PMID:28915716 PMID:28973083 PMID:28993434 PMID:29084914 PMID:29161300 PMID:29192238 PMID:29240602 PMID:29288066 PMID:29321669 PMID:29339979 PMID:29360161 PMID:29368341 PMID:29371908 PMID:29394989 PMID:29433453 PMID:29446198 PMID:29478780 PMID:29492181 PMID:29681614 PMID:29752822 PMID:29907814 PMID:29909963 PMID:29988080 PMID:30039884 PMID:30078507 PMID:30287823 PMID:30415210 PMID:30702160 PMID:31131967 PMID:31825140 PMID:32295079 PMID:32444794, PMID:22187320 RGD:9068467 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO protein:altered localization:pancreas RGD PMID:17242465 RGD:2326105 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Cab39 calcium binding protein 39 disease_progression ISO RGD PMID:28197410 RGD:14398834 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cacybp calcyclin binding protein disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:18765951 RGD:2326146 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capn10 calpain 10 susceptibility ISO DNA:SNP:intron:rs3792267 (human) RGD PMID:20178008 RGD:4107073 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Casp8 caspase 8 susceptibility ISO DNA:SNP: :rs1045485 (human)
DNA:deletion, insertion:promoter (human)
RGD PMID:19843670, PMID:18483392 RGD:2317230, RGD:2315744 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 susceptibility
treatment
ISO DNA:snp:promoter:g.-1263A>G (human) RGD PMID:20357690, PMID:19209030 RGD:13451540, RGD:13462046 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase disease_progression ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1 ClinVar PMID:25741868 PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Cckar cholecystokinin A receptor IEP
ISO
mRNA:increased expression:pancreas RGD PMID:8222074, PMID:10457335 RGD:4110822, RGD:4110817 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Cckbr cholecystokinin B receptor disease_progression
susceptibility
IEP
IDA
ISO
mRNA:increased expression:pancreas RGD PMID:8302799, PMID:8222074, PMID:1458479, PMID:15688412 RGD:4110823, RGD:4110822, RGD:4110821, RGD:4110829 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057, PMID:10225458 RGD:7483623 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment
ISO human cells in a mouse model
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:22722256, PMID:11159909, PMID:17541034 RGD:13451541, RGD:13452385, RGD:13462059 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:pancreas RGD PMID:12761880 RGD:2317610 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd24 CD24 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc42 cell division cycle 42 severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:28181096 RGD:13452244 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk4 cyclin-dependent kinase 4 susceptibility
disease_progression
ISO
IEP
protein:increased expression:islet of Langerhans (human)
protein:increased expression:islet of Langerhans, nucleus (rat)
protein:increased expression:pancreas (mouse)
RGD PMID:22761470, PMID:24531709, PMID:22477723, PMID:11159909 RGD:13452384, RGD:13452387, RGD:13452386, RGD:13452385 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:mutations:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:10627132 PMID:26098869, PMID:18772397 RGD:5490966 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20876774 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cftr CF transmembrane conductance regulator no_association
onset
ISO RGD PMID:17072959, PMID:16227367 RGD:2317157, RGD:2317156 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chek1 checkpoint kinase 1 disease_progression ISO DNA:SNP: :35G>A (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:19555390, PMID:19793693 RGD:2317583, RGD:2317580 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 1:80,549,051...80,580,665
Ensembl chr 1:80,549,043...80,580,662
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cycs cytochrome c, somatic ISO RGD PMID:11920648 RGD:2317614 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 susceptibility ISO DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:19642097 RGD:2317618 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 EXP CTD Direct Evidence: therapeutic CTD PMID:10026857 PMID:10326030 PMID:10415878 PMID:11332152 PMID:11377651 PMID:12042985 PMID:12649565 PMID:12698877 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Daxx death-domain associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas
CTD PMID:17443278 PMID:19020767, PMID:18309485, PMID:20072795 RGD:2317630, RGD:2317629 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31838052 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G E2f1 E2F transcription factor 1 treatment IEP RGD PMID:28344092 RGD:13838737 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208748 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression:pancreas RGD PMID:1347773, PMID:19506583 RGD:2317650, RGD:5490965 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27720938, PMID:17452677, PMID:19506583 RGD:5131631, RGD:5490965 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 ISO protein:increased expression:serum (human) RGD PMID:15796914 RGD:10045549 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Epcam epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Epha3 Eph receptor A3 ISO RGD PMID:14670182 RGD:2317720 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:3' utr:c.*197G>T (rs3212986) (human) RGD PMID:27050953 RGD:13207426 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit treatment ISO pancreatic adenocarcinoma;DNA:SNPs: :rs1799793,rs1052555(human)
DNA,protein:SNPs:exons:rs1799793,rs1052559(human)
RGD PMID:18544627, PMID:21404106, PMID:16458430 RGD:2317223, RGD:11252206, RGD:2317228 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO pancreatic adenocarcinoma;DNA:SNP: :rs1800067(human) RGD PMID:18544627 RGD:2317223 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP protein:increased expression:pancreas RGD PMID:22222375 RGD:9588324 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fanca FA complementation group A ISO DNA,Protein:polymorphisms:exons:c.377C>G, c.661A>G (human) RGD PMID:15591268 RGD:2317735 NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063
JBrowse link
G Fancc FA complementation group C ISO DNA:nonsense mutation (human) RGD PMID:16243825, PMID:15695377 RGD:2317238, RGD:2317239 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fancg FA complementation group G ISO RGD PMID:16243825 RGD:2317238 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
JBrowse link
G Faslg Fas ligand severity
resistance
ISO DNA:polymorphism:promoter:-844>>T (human) RGD PMID:11115536, PMID:12370548, PMID:18483392 RGD:2317745, RGD:2317744, RGD:2315744 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf2 fibroblast growth factor 2 severity ISO mRNA:increased expression:pancreas
protein:increased expression:bile
RGD PMID:9293890, PMID:11562741, PMID:11478488, PMID:12670449 RGD:2317762, RGD:2317760, RGD:2317765, RGD:2317759 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IMP RGD PMID:16528542 RGD:11049499 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Fscn1 fascin actin-bundling protein 1 severity ISO protein:increased expression:pancreas RGD PMID:17696949 RGD:2317785 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003754 NCBI chr 1:89,502,561...89,510,146
Ensembl chr 1:89,502,562...89,509,343
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO CTD Direct Evidence: therapeutic CTD PMID:19003803 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gdnf glial cell derived neurotrophic factor severity ISO RGD PMID:18652760 RGD:2324925 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gli1 GLI family zinc finger 1 ISO RGD PMID:21186299, PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gli3 GLI family zinc finger 3 ISO RGD PMID:18772397 RGD:5490966 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:12771991 RGD:2317256 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:19536452, PMID:19786118 RGD:2317805, RGD:2317804 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hgf hepatocyte growth factor ISO protein:increased expression:serum RGD PMID:20017454 RGD:2317895 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16628086 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 1:191,344,979...191,474,143
Ensembl chr 1:191,344,979...191,474,142
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 disease_progression ISO RGD PMID:21833720 RGD:10402768 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:11815996 RGD:2325165 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19152246 RGD:2317258 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:19064563 RGD:2306689 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO RGD PMID:14559833, PMID:19732452, PMID:19885860 RGD:2317651, RGD:2317642, RGD:2317640 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 disease_progression
susceptibility
ISO protein:increased expression:serum
DNA:polymorphism: :-1082G>A (human)
RGD PMID:17235586, PMID:30304975, PMID:30610790, PMID:19250218 RGD:2317655, RGD:14975257, RGD:14975253, RGD:2317653 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789, PMID:12808442 RGD:2317669, RGD:2317670 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 treatment ISO RGD PMID:11748276 RGD:8549514 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:7787209 RGD:2311069 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphisms:promoter:-511C>T, -31T>C (human)
protein:increased expression:serum (human)
RGD PMID:19251436, PMID:7787209 RGD:2317215, RGD:2311069 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9080118 RGD:8663440 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il24 interleukin 24 ISO CTD Direct Evidence: therapeutic CTD PMID:15580305 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il3 interleukin 3 ISO protein:increased expression:serum RGD PMID:15843207 RGD:2317663 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 disease_progression ISO protein:increased expression:blood RGD PMID:19957810, PMID:12097255, PMID:10404069 RGD:2317261, RGD:2317265, RGD:2317267 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789 RGD:2317669 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 disease_progression ISO RGD PMID:30610790, PMID:30304975 RGD:14975253, RGD:14975257 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ilk integrin-linked kinase ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Ins2 insulin 2 susceptibility
disease_progression
ISO associated with Diabetes Mellitus
DNA:Polymorphism:promoter:-23 HphI (human)
associated with Diabetes Mellitus, Non-Insulin-Depend
RGD PMID:19375425, PMID:19152242, PMID:19628082, PMID:19572116 RGD:2317250, RGD:2317253, RGD:2317245, RGD:2317247 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itga11 integrin subunit alpha 11 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:67,566,874...67,683,973
Ensembl chr 8:67,615,635...67,683,973
JBrowse link
G Itga4 integrin subunit alpha 4 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itga9 integrin subunit alpha 9 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12385004, PMID:19930156 RGD:5684397 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Klf5 Kruppel-like factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Kras KRAS proto-oncogene, GTPase disease_progression ISO ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 PMID:14520703 PMID:15696205 PMID:15842656 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17332249 PMID:17384584 PMID:17704260 PMID:17910045 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19029981 PMID:19047918 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19358724 PMID:19424582 PMID:19679400 PMID:19773371 PMID:19881948 PMID:20609353 PMID:20805368 PMID:20921462 PMID:20921465 PMID:20949522 PMID:21079152 PMID:21169357 PMID:21228335 PMID:21398618 PMID:21699781 PMID:21975775 PMID:22025163 PMID:22235099 PMID:22407852 PMID:22499344 PMID:22683711 PMID:22897852 PMID:23014527 PMID:23096712 PMID:23406027 PMID:24033266 PMID:24694877 PMID:25044103 PMID:25157968 PMID:25695684 PMID:25961927 PMID:26372703 PMID:26390243 PMID:28492532 PMID:29298116 PMID:31891627, PMID:11115351, PMID:18772397, PMID:19506583 RGD:1581761, RGD:5490966, RGD:5490965 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO RGD PMID:22095073 RGD:11570404 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29384525 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lig3 DNA ligase 3 resistance ISO DNA:SNP:intron:rs 2074522 (human) RGD PMID:19147782 RGD:2317363 NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
JBrowse link
G Lig4 DNA ligase 4 susceptibility ISO associated with Diabetes Mellitus;DNA:polymorphism: :54C>T (human) RGD PMID:19147782 RGD:2317363 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lum lumican disease_progression ISO DNA:SNP: :rs2268578 (human) RGD PMID:19843670, PMID:17671699 RGD:2317230, RGD:2317682 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor no_association ISO DNA:point mutations, deletions:cds:multiple (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:9174057, PMID:17072959 RGD:2325804, RGD:2317157 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO RGD PMID:18772397 RGD:5490966 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; protein:increased expression:multiple organs
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653 PMID:21252315, PMID:17278096 RGD:2317340 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity IEP
ISO
protein:increased expression:pancreas (rat)
mRNA:increased expression:pancreas (human)
RGD PMID:9211490, PMID:19506583, PMID:15448002 RGD:2317613, RGD:5490965, RGD:2317235 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A ISO RGD PMID:16434023 RGD:2317701 NCBI chr 9:44,033,433...44,126,946
Ensembl chr 9:44,033,436...44,126,919
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO protein:decreased expression:neuroendocrine tumor (human) RGD PMID:19118063 RGD:2317628 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mir107 microRNA 107 severity ISO RGD PMID:28720759 RGD:14975279 NCBI chr 1:253,128,250...253,128,336
Ensembl chr 1:253,128,250...253,128,336
JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:increased expression:pancreas RGD PMID:20137856, PMID:20350215 RGD:2317704, RGD:2317703 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased activity:pancreatic juice
CTD PMID:30603057, PMID:7635566, PMID:11961486 RGD:2325766, RGD:2325752 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas
protein:increased expression:serum
CTD PMID:22952646, PMID:18445772, PMID:7635566, PMID:19629003, PMID:18030366 RGD:2325849, RGD:2325766, RGD:2325831, RGD:2325854 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase resistance ISO DNA:polymorphism:promoter:-463G>A (human) RGD PMID:18205184 RGD:2317406 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism
associated with Pancreatic Disease; protein:increased expression:pancreas
CTD PMID:11751476, PMID:19843662, PMID:18281514, PMID:17785569, PMID:17019794 RGD:2326052, RGD:2326056, RGD:2326062, RGD:2326060 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Mtap methylthioadenosine phosphorylase ISO DNA, protein:deletion, decreased activity:pancreas: RGD PMID:15534104 RGD:2317952 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:polymorphism: :677C>T (human) RGD PMID:16737574 RGD:2317120 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23149918 RGD:10040959 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility
no_association
ISO DNA:Polymorphism: :rs1805087 (human) RGD PMID:18843018, PMID:16737574 RGD:2317118, RGD:2317120 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human)
DNA:SNPs:intron, exon:rs162049, p.H595Y (rs10380) (human)
RGD PMID:18843018, PMID:18515090 RGD:2317118, RGD:2325772 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression:pancreas
protein:increased secretion:bile
RGD PMID:14654947, PMID:18039393, PMID:18383873, PMID:19129927, PMID:19055478, PMID:18575732 RGD:2317984, RGD:2324639, RGD:2324637, RGD:2317987, RGD:2324622, RGD:2324635 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc16 mucin 16, cell surface associated ISO protein:increased expression:serum RGD PMID:19377061 RGD:2325129 NCBI chr 8:18,438,838...18,639,777 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:peripheral blood mononuclear cell
protein:increased expression:pancreas
mRNA:increased expression:pancreas
RGD PMID:16274046, PMID:17595659, PMID:20303649, PMID:11751498, PMID:17406026 RGD:2324931, RGD:2324922, RGD:2324914, RGD:2324891, RGD:2324923 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:increased glycosylation:serum
protein:increased expression:pancreas
RGD PMID:19377061, PMID:14654947 RGD:2325129, RGD:2317984 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming ISO protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25961927, PMID:22024988 RGD:7240699 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 ISO human gene in a mouse model RGD PMID:25071868 RGD:9590074 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism (human)
DNA:polymorphisms,haplotype: :
RGD PMID:18006927, PMID:18006927, PMID:18499698 RGD:2317170, RGD:2317170, RGD:2317168 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphism (human) RGD PMID:18027363 RGD:2317169 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ncam1 neural cell adhesion molecule 1 severity
disease_progression
ISO RGD PMID:10374842, PMID:11249065 RGD:2326075, RGD:2326074 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:15861417 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngfr nerve growth factor receptor severity ISO mRNA:increased expression:tumor:associated with longer overall survival (human) RGD PMID:16704535 RGD:5508229 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression ISO protein:increased expression:pancreas RGD PMID:11196200, PMID:11687972, PMID:15165031 RGD:2325262, RGD:2325257, RGD:2325248 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:17297654 RGD:2325328 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20660371 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20101243 PMID:26098869 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Nrp1 neuropilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15956974 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 severity ISO mRNA:increased expression:tumor:associated with increased tumor aggressiveness (human) RGD PMID:16704535 RGD:5508229 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO DNA:mutation:pancreas RGD PMID:16941478 RGD:2325656 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex treatment ISO mRNA:increased expression:pancreas RGD PMID:26045769, PMID:25370920 RGD:11058437, RGD:28867232 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase disease_progression ISO DNA:polymorphism: :2657G>A (human)
DNA:polymorphism: :rs1052133 (human)
RGD PMID:17230526, PMID:18559563 RGD:2317132, RGD:2317130 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Palb2 partner and localizer of BRCA2 susceptibility ISO DNA:nonsense mutations:exon:172_175del, 3116del, 3256C>T (human)
ClinVar Annotator: match by term: Pancreatic cancer 3
ClinVar Annotator: match by term: Cancer of the pancreas
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:17200668 PMID:17200671 PMID:18302019 PMID:19264984 PMID:20122277 PMID:20412113 PMID:20582465 PMID:20589654 PMID:21165770 PMID:21285249 PMID:21365267 PMID:23561644 PMID:23977390 PMID:24033266 PMID:24061862 PMID:24136930 PMID:24415441 PMID:24448499 PMID:24556926 PMID:24728327 PMID:25099575 PMID:25186627 PMID:25330149 PMID:25356972 PMID:25452441 PMID:25575445 PMID:25741868 PMID:25959805 PMID:25980754 PMID:26083025 PMID:26098869 PMID:26270727 PMID:26283626 PMID:26315354 PMID:26411315 PMID:26467025 PMID:26489409 PMID:26564480 PMID:26681312 PMID:26720728 PMID:26845104 PMID:27038244 PMID:27099641 PMID:27106063 PMID:27153395 PMID:27433846 PMID:27624329 PMID:27783279 PMID:28158555 PMID:28279176 PMID:28492532 PMID:28724667 PMID:28726808 PMID:28779002 PMID:29387807 PMID:29522266 PMID:29752822 PMID:29909963 PMID:30287823 PMID:30638972 PMID:31636395 PMID:31843900 PMID:31844177 PMID:32295079 PMID:32566746, PMID:19264984 RGD:2325776 NCBI chr 1:192,064,586...192,088,547
Ensembl chr 1:192,064,589...192,088,520
JBrowse link
G Palld palladin, cytoskeletal associated protein susceptibility ISO DNA, mRNA:missense mutation, increased expression:pancreas:p.P239S (human)
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
protein:increased expression, alternative form:pancreas, fibroblast
ClinVar
CTD
OMIM
PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:20436683 PMID:24033266 PMID:25741868 PMID:28492532, PMID:17194196, PMID:20436683 RGD:2325782, RGD:2325779 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pbrm1 polybromo 1 ISO RGD PMID:23355908 RGD:8694154 NCBI chr16:7,103,714...7,202,899
Ensembl chr16:7,103,998...7,200,362
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO mRNA:increased expression:pancreas RGD PMID:7665222, PMID:14695158 RGD:2324851, RGD:2324850 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19077462 PMID:25086665 PMID:26098869 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pfn1 profilin 1 ISO RGD PMID:16215274 RGD:2317552 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10467400 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Polb DNA polymerase beta disease_progression ISO DNA:polymorphisms: :165A>G, 2133T>C (human) RGD PMID:17230526 RGD:2317132 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta disease_progression ISO RGD PMID:17652168, PMID:17652168 RGD:2324872, RGD:2324872 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma susceptibility ISO DNA:polymorphism: :p.P12A (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:11034103 PMID:11741176, PMID:19436234, PMID:19152448 RGD:2317460, RGD:2317462 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptch1 patched 1 ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:19077462, PMID:19396459 RGD:2324910 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848, PMID:19506583 RGD:5490965 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA, protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
DNA:polymorphisms: :-1195A>A ,-765G>C (human)
CTD PMID:10485483 PMID:10657949 PMID:15705899 PMID:16820089, PMID:19820419, PMID:19062735, PMID:20216081, PMID:19422084 RGD:2317179, RGD:5135527, RGD:2317175, RGD:2317184 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Rabl3 RAB, member of RAS oncogene family-like 3 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 5
CTD
OMIM
ClinVar
PMID:31406347 NCBI chr11:66,049,635...66,078,669
Ensembl chr11:66,049,635...66,078,669
JBrowse link
G Rad51 RAD51 recombinase IEP protein:increased expression:pancreas (rat) RGD PMID:20197614 RGD:9831172 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad54l RAD54 like ISO DNA:SNP:exon:rs1048771 (human) RGD PMID:16540687 RGD:2317365 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA:decreased expression:pancreas (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22614916, PMID:16424023 RGD:9835037 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21699781 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Recql RecQ like helicase ISO DNA:SNPs:introns
DNA:SNP:3'utr:rs13035 (human)
RGD PMID:18422747, PMID:19768149, PMID:16540687 RGD:2317370, RGD:2317369, RGD:2317365 NCBI chr 4:176,581,892...176,606,520
Ensembl chr 4:176,581,897...176,606,382
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO RGD PMID:9918209 RGD:2298892 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene disease_progression ISO protein:increased expression:pancreas RGD PMID:16269310 RGD:2324926 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO RGD PMID:19568409 RGD:2324950 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Runx3 RUNX family transcription factor 3 disease_progression ISO DNA:hypermethylation, loss of heterozygosity (human) RGD PMID:18475302 RGD:2324956 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Rxra retinoid X receptor alpha ISO RGD PMID:19152448 RGD:2317462 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase ISO RGD PMID:14508516 RGD:2317190 NCBI chr 6:115,572,683...115,616,904
Ensembl chr 6:115,572,649...115,616,859
JBrowse link
G Serpina1 serpin family A member 1 disease_progression ISO RGD PMID:2323846 RGD:2324960 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:19506583 RGD:5490965 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18728667 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Smad2 SMAD family member 2 ISO mRNA:increased expression:pancreas (human) RGD PMID:10505717 RGD:14394490 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic cancer
DNA:mutations:exon
OMIM
ClinVar
PMID:8898652 PMID:9679244 PMID:9811934 PMID:10479724 PMID:10764709 PMID:10775259 PMID:10797267 PMID:11274206 PMID:12821112 PMID:14715079 PMID:15014009 PMID:15031030 PMID:15235019 PMID:16613914 PMID:17873119 PMID:17994767 PMID:20101697 PMID:22331366 PMID:25741868 PMID:26619011 PMID:27595937 PMID:27978560 PMID:28135145 PMID:28492532 PMID:28528518, PMID:18772397 RGD:5490966 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad7 SMAD family member 7 ISO mRNA:increased expression:pancreas (human) RGD PMID:10498890 RGD:14394510 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:23355908 RGD:8694154 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Smo smoothened, frizzled class receptor ISO protein:increased expression:pancreas RGD PMID:19460966, PMID:19396459 RGD:2324978, RGD:2324910 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO RGD PMID:17726579 RGD:2302550 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snw1 SNW domain containing 1 susceptibility ISO DNA:snp:intron: T>A (human) (rs1477261) RGD PMID:20056645 RGD:11035249 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sod1 superoxide dismutase 1 ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 disease_progression
susceptibility
ISO protein:decreased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.A16V (human)
CTD PMID:17895890, PMID:12499913, PMID:12700280, PMID:18205184 RGD:2317410, RGD:1581235, RGD:2317406 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19896093 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15970685 RGD:1581363 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Sstr1 somatostatin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 6:79,252,914...79,258,611
Ensembl chr 6:79,254,339...79,258,611
JBrowse link
G Sstr2 somatostatin receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15259086 PMID:17625444 PMID:19917848 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22348037 PMID:23845849 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
PMID:26098869 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sycp1 synaptonemal complex protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr 2:205,274,766...205,426,869
Ensembl chr 2:205,274,769...205,426,869
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16965396 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tgfa transforming growth factor alpha ISO
IMP
mRNA, protein:increased expression:pancreas RGD PMID:1401070, PMID:19506583, PMID:17785207 RGD:2317473, RGD:5490965, RGD:2317468 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:23992306, PMID:18787407, PMID:16933058 RGD:2325015, RGD:2325018 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO DNA:deletion, frameshift mutations (human)
DNA:mutations:exon
protein:increased expresssion:pancreas
mRNA:increased expresssion:pancreas
RGD PMID:9850059, PMID:18772397, PMID:11866987, PMID:9365135 RGD:2317501, RGD:5490966, RGD:2317499, RGD:2317502 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30108682 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation (human) RGD PMID:10766168, PMID:20203415, PMID:16757110 RGD:2325028, RGD:2325021, RGD:2325023 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: therapeutic CTD PMID:16211219 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11234897 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 ISO DNA:mutations:exon
ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:1565143 PMID:1565144 PMID:1683921 PMID:7732013 PMID:7887414 PMID:8164043 PMID:8423216 PMID:8825920 PMID:9047394 PMID:9242456 PMID:9569050 PMID:10411893 PMID:10797439 PMID:10864200 PMID:11101847 PMID:11139324 PMID:11479205 PMID:11782540 PMID:12007217 PMID:12619118 PMID:12672316 PMID:12826609 PMID:15004724 PMID:15381368 PMID:15390294 PMID:15607980 PMID:15607981 PMID:15951970 PMID:15977174 PMID:16401470 PMID:16489069 PMID:16682957 PMID:16818505 PMID:17540308 PMID:17606709 PMID:17636407 PMID:18391940 PMID:18511570 PMID:19127115 PMID:19556618 PMID:19881536 PMID:20113312 PMID:20128691 PMID:20407015 PMID:20516128 PMID:20689556 PMID:20693561 PMID:21187651 PMID:21305319 PMID:21343334 PMID:21484931 PMID:21519010 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22006311 PMID:22110706 PMID:22186996 PMID:22233476 PMID:22698404 PMID:22811390 PMID:22899716 PMID:22915647 PMID:23161690 PMID:23246812 PMID:23263379 PMID:23538418 PMID:23792586 PMID:23873029 PMID:24033266 PMID:24381225 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24641375 PMID:24651012 PMID:24677579 PMID:24810334 PMID:25157968 PMID:25584008 PMID:25741868 PMID:25787918 PMID:25952993 PMID:26230955 PMID:26390243 PMID:26467025 PMID:26585234 PMID:26619011 PMID:26681312 PMID:26822237 PMID:26845104 PMID:27153395 PMID:27276561 PMID:27374712 PMID:27463065 PMID:27516001 PMID:27680515 PMID:27683180 PMID:27895058 PMID:27959731 PMID:28349240 PMID:28369373 PMID:28453743 PMID:28492532 PMID:29478780 PMID:29489754 PMID:30076369 PMID:30224644 PMID:30327374 PMID:30816478 PMID:31775759 PMID:32000721, PMID:18772397 RGD:5490966 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO RGD PMID:11585747 RGD:2325154 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tymp thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17443278, PMID:19671868 RGD:2325156 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO protein:increased expression:pancreatic neoplasm (human) RGD PMID:12149149 RGD:5133269 NCBI chr13:85,376,716...85,443,976
Ensembl chr13:85,376,716...85,443,976
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C no_association ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:12806614, PMID:17072959 RGD:2317503, RGD:2317157 NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:17652277 RGD:2325162 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfb vascular endothelial growth factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24604347 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation, deletion:promoter (human)
associated with Hippel-Lindau Disease;DNA:missense mutation:exon:p.R238Q (human)
RGD PMID:19690016, PMID:9488521 RGD:2325169, RGD:2325176 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Wnt9a Wnt family member 9A ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr10:45,659,045...45,686,103
Ensembl chr10:45,659,143...45,681,393
JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19196508 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO DNA:polymorphism:intron:AF076952 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Xpo5 exportin 5 ISO mRNA:decreased expression:pancreas (mouse) RGD PMID:26516699 RGD:11041739 NCBI chr 9:17,125,201...17,163,170
Ensembl chr 9:17,125,201...17,163,170
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO DNA:SNP:exon:rs1799782 (human) RGD PMID:16520463 RGD:2317367 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 ISO DNA:polymorphism: :p.R188H (human)
DNA:SNP:exon:rs3218536 (human)
RGD PMID:17986315, PMID:16540687 RGD:2317507, RGD:2317365 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO DNA:SNP:cd:rs861539 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
G Znrf3 zinc and ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr14:85,527,099...85,586,294 JBrowse link
Adult Pancreatic Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203118 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
duodenal gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: : RGD PMID:17135306 RGD:2317341 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
Familial Pancreatic Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 ISO mRNA:increased expression:pancreas, carcinoma (human) RGD PMID:16815451 RGD:5685662 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1r insulin-like growth factor 1 receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Men1 menin 1 ISO DNA:mutations: :
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653, PMID:15944766 RGD:2317354 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity ISO associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human) RGD PMID:12114431 RGD:2317605 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypomethylation:promoter (human) RGD PMID:17278096 RGD:2317340 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701, PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
Gastro-Enteropancreatic Neuroendocrine Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd53 Cd53 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
JBrowse link
G Cd86 CD86 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:86,420,757...86,509,454
Ensembl chr10:86,421,582...86,509,454
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Notch2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Pou2f2 POU class 2 homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:81,966,791...82,049,116
Ensembl chr 1:81,964,104...82,004,538
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
Glucagonoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Men1 menin 1 ISO DNA:deletion:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653, PMID:20138042 RGD:2317288 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701, PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Sstr4 somatostatin receptor 4 ISO RGD PMID:8132773 RGD:2324994 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
JBrowse link
islet cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler disease_progression ISO protein:decreased expression:pancreas: RGD PMID:24148618 RGD:9586032 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:22761470 RGD:13452384 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Daxx death-domain associated protein disease_progression ISO RGD PMID:21252315 RGD:9587819 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP protein:increased expression:insulinoma (rat) RGD PMID:7925129 RGD:2308920 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
Islet Cell Tumor Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1b kinesin family member 1B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:18334619 PMID:18726616 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Mpz myelin protein zero ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 PMID:25741868 NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
JBrowse link
G Ret ret proto-oncogene ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:2660074 PMID:3078962 PMID:7536460 PMID:7824936 PMID:7845675 PMID:7906417 PMID:7906866 PMID:7911697 PMID:7977365 PMID:8570194 PMID:8595427 PMID:8782503 PMID:8797874 PMID:8880581 PMID:8918855 PMID:9242375 PMID:9620546 PMID:9681850 PMID:9839497 PMID:10369718 PMID:10445857 PMID:10679286 PMID:11230481 PMID:11351254 PMID:15277225 PMID:15281979 PMID:15320968 PMID:16715139 PMID:17108110 PMID:17848262 PMID:18058472 PMID:18073307 PMID:18209889 PMID:18252215 PMID:18322301 PMID:18541894 PMID:19041016 PMID:19240193 PMID:19255327 PMID:19826964 PMID:19906784 PMID:20065189 PMID:20368568 PMID:20516206 PMID:20847059 PMID:21253810 PMID:21422803 PMID:21455200 PMID:21470995 PMID:21479187 PMID:21551259 PMID:21765987 PMID:21810974 PMID:21986619 PMID:22025146 PMID:22199277 PMID:22233172 PMID:22359510 PMID:22676344 PMID:22992277 PMID:23056499 PMID:23067224 PMID:24033266 PMID:24728327 PMID:25157968 PMID:25637381 PMID:25741868 PMID:25810047 PMID:26084817 PMID:26332594 PMID:26467025 PMID:26489027 PMID:27379493 PMID:27539324 PMID:27807060 PMID:28492532 PMID:28946813 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12364472 PMID:12618761 PMID:14500403 PMID:15328326 PMID:16314641 PMID:16317055 PMID:17102082 PMID:17200167 PMID:18362451 PMID:18840642 PMID:19454582 PMID:19802898 PMID:22835832 PMID:23083876 PMID:23175444 PMID:23282968 PMID:23512077 PMID:24033266 PMID:24102379 PMID:24659481 PMID:25298897 PMID:25741868 PMID:25972245 PMID:26642834 PMID:26719882 PMID:28374168 PMID:28492532 PMID:28503760 PMID:28973655 PMID:29386252 PMID:29951630 PMID:30352407 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 PMID:25741868 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:10657297 PMID:11156372 PMID:11526495 PMID:12007193 PMID:12111639 PMID:12386824 PMID:12696072 PMID:14557476 PMID:15032977 PMID:15623805 PMID:18678321 PMID:21565294 PMID:21979946 PMID:22584711 PMID:22703879 PMID:23175444 PMID:23666964 PMID:24033266 PMID:24728327 PMID:24886695 PMID:25149476 PMID:25694510 PMID:25695889 PMID:25741868 PMID:26467025 PMID:27153395 PMID:27279923 PMID:28128698 PMID:28164237 PMID:28492532 PMID:29386252 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604
JBrowse link
Melanoma-Pancreatic Cancer Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome
ClinVar Annotator: match by term: FAMILIAL ATYPICAL MULTIPLE MOLE MELANOMA-PANCREATIC CARCINOMA SYNDROME
OMIM
ClinVar
PMID:7566978 PMID:7632931 PMID:7647780 PMID:7666917 PMID:7670475 PMID:7718873 PMID:7777061 PMID:7780957 PMID:7882348 PMID:7923152 PMID:7970734 PMID:7972006 PMID:7987387 PMID:7987388 PMID:8012957 PMID:8552158 PMID:8561866 PMID:8570179 PMID:8573142 PMID:8595411 PMID:8603820 PMID:8668202 PMID:8710906 PMID:8755727 PMID:8841025 PMID:9049826 PMID:9133447 PMID:9166859 PMID:9185756 PMID:9212218 PMID:9324288 PMID:9389568 PMID:9416844 PMID:9425228 PMID:9473234 PMID:9516223 PMID:9660926 PMID:9699728 PMID:9751050 PMID:9782052 PMID:9808520 PMID:9823374 PMID:9856796 PMID:9916806 PMID:9935245 PMID:10229204 PMID:10389768 PMID:10390011 PMID:10398427 PMID:10400925 PMID:10498896 PMID:10508477 PMID:10627132 PMID:10667595 PMID:10719365 PMID:10738302 PMID:10854221 PMID:10869234 PMID:10874641 PMID:10951521 PMID:10956390 PMID:11156381 PMID:11360201 PMID:11506491 PMID:11556834 PMID:11579459 PMID:11595726 PMID:11687599 PMID:11807902 PMID:11815963 PMID:12072543 PMID:12352668 PMID:12417040 PMID:12461329 PMID:12485439 PMID:12517341 PMID:12532425 PMID:12538475 PMID:12549483 PMID:12606942 PMID:12700603 PMID:12853981 PMID:12894891 PMID:14508519 PMID:14679123 PMID:14735200 PMID:15075790 PMID:15122588 PMID:15146471 PMID:15173226 PMID:15235029 PMID:15705881 PMID:15761864 PMID:15860862 PMID:15945100 PMID:16169933 PMID:16234564 PMID:16354195 PMID:16397522 PMID:16614725 PMID:16818274 PMID:16896043 PMID:16905682 PMID:17047042 PMID:17218939 PMID:17255954 PMID:17370310 PMID:17397031 PMID:17713569 PMID:18023021 PMID:18025365 PMID:18178632 PMID:18335566 PMID:18337833 PMID:18363633 PMID:18519632 PMID:18573309 PMID:18803811 PMID:18843795 PMID:18983535 PMID:19141585 PMID:19260062 PMID:19320745 PMID:19331830 PMID:19360740 PMID:19523171 PMID:19571771 PMID:19690981 PMID:19799798 PMID:20093296 PMID:20340136 PMID:20505745 PMID:20539244 PMID:20653773 PMID:20876876 PMID:21085193 PMID:21150883 PMID:21325014 PMID:21462282 PMID:21619050 PMID:21801156 PMID:21893440 PMID:22292911 PMID:22368299 PMID:22440936 PMID:22636603 PMID:22703879 PMID:22841127 PMID:22995991 PMID:23190892 PMID:23371019 PMID:23613284 PMID:24033266 PMID:24185512 PMID:24659262 PMID:24728327 PMID:24733792 PMID:24737347 PMID:25064638 PMID:25078331 PMID:25186627 PMID:25318351 PMID:25356972 PMID:25372287 PMID:25479140 PMID:25741868 PMID:25780468 PMID:25787093 PMID:25803691 PMID:25846456 PMID:25980754 PMID:26104880 PMID:26206375 PMID:26225579 PMID:26295973 PMID:26381259 PMID:26467025 PMID:26474073 PMID:26483394 PMID:26498684 PMID:26581427 PMID:26601054 PMID:26650572 PMID:26658419 PMID:26670561 PMID:26681309 PMID:26775776 PMID:26845104 PMID:26976419 PMID:27181379 PMID:27473757 PMID:27621404 PMID:27626068 PMID:27701467 PMID:27756164 PMID:27960642 PMID:27978560 PMID:28135145 PMID:28146043 PMID:28166811 PMID:28410231 PMID:28454591 PMID:28492532 PMID:28521409 PMID:28592523 PMID:28599463 PMID:28640387 PMID:28717660 PMID:28726808 PMID:28765326 PMID:28767289 PMID:28830827 PMID:28866070 PMID:28873162 PMID:28944238 PMID:28979722 PMID:29263814 PMID:29360161 PMID:29506128 PMID:29533785 PMID:29541281 PMID:29543703 PMID:29758216 PMID:29774366 PMID:30038052 PMID:30207590 PMID:30339520 PMID:31921681 PMID:32113160 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
non-functioning pancreatic endocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk4 cyclin-dependent kinase 4 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
pancreatic adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 ISO mRNA:decreased expression:pancreas RGD PMID:11875720 RGD:13831350 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Akt3 AKT serine/threonine kinase 3 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:25053516 RGD:13462053 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:25050737 RGD:13782144 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:missense mutations:cds:p.V126D, p.A148T (human)
ClinVar Annotator: match by term: Pancreatic adenocarcinoma
ClinVar PMID:7780957 PMID:8521414 PMID:8595405 PMID:8723678 PMID:9324288 PMID:9751050 PMID:9823374 PMID:10491434 PMID:11477665 PMID:11500805 PMID:11687599 PMID:12072543 PMID:16234564 PMID:16896043 PMID:16905682 PMID:18573309 PMID:21462282 PMID:25157968 PMID:25356972 PMID:25741868 PMID:26619011 PMID:26681309 PMID:26775776 PMID:28492532 PMID:28830827 PMID:29983899, PMID:16397522 RGD:8552283 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9065402 PMID:9294210 PMID:9500465 PMID:9927029 PMID:10192393 PMID:10398436 PMID:10435629 PMID:10655994 PMID:10666372 PMID:25157968 PMID:26619011 PMID:26822237 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:21448932 RGD:11352272 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO Human cells in a mouse model RGD PMID:28797284 RGD:13838736 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:16397024 PMID:23220880 PMID:26619011 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 PMID:7739708 PMID:8766942 PMID:9626141 PMID:12727968 PMID:12970318 PMID:15126527 PMID:16507630 PMID:21835143 PMID:23536913 PMID:24855271 PMID:25157968 PMID:26619011 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:11854392 RGD:14700985 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrg histidine-rich glycoprotein disease_progression ISO RGD PMID:21713765 RGD:11041886 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Jak1 Janus kinase 1 treatment ISO human cell line in a mouse model RGD PMID:29328487 RGD:13838743 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16434492 PMID:16618717 PMID:18316791 PMID:18794081 PMID:19075190 PMID:19114683 PMID:19679400 PMID:20921462 PMID:20921465 PMID:21228335 PMID:22407852 PMID:22722830 PMID:23325582 PMID:25157968 PMID:26619011 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr 1:214,182,232...214,197,184
Ensembl chr 1:214,182,830...214,197,184
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 treatment
severity
ISO human tissue in a mouse model
protein:increased expression:pancreas (human)
RGD PMID:28849200, PMID:19513748 RGD:13838804, RGD:13838840 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:18042262 PMID:26619011 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk10 mitogen activated protein kinase 10 severity ISO DNA:SNP:intron: (rs2589506) (human) RGD PMID: RGD:13838853 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:22517435 RGD:14348976 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Med12 mediator complex subunit 12 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:20436683 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 PMID:15805248 PMID:15930273 PMID:16906227 PMID:16930767 PMID:17376864 PMID:17673550 PMID:18676830 PMID:18725974 PMID:19029981 PMID:19223544 PMID:19366826 PMID:19513541 PMID:19903786 PMID:20453058 PMID:20619739 PMID:21430269 PMID:21558396 PMID:21824802 PMID:22120714 PMID:22162582 PMID:22162589 PMID:22271473 PMID:22658544 PMID:22729222 PMID:22729223 PMID:22729224 PMID:23066039 PMID:23100325 PMID:23246288 PMID:23408298 PMID:23888070 PMID:24033266 PMID:24265155 PMID:24782230 PMID:25157968 PMID:25741868 PMID:26266975 PMID:26266985 PMID:26619011 PMID:26822237 PMID:27626068 PMID:27631024 PMID:28492532 PMID:29446767 PMID:31775759 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Plat plasminogen activator, tissue type ISO mRNA:increased expression:pancreas (human) RGD PMID:16733850 RGD:11541045 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 PMID:28492532 NCBI chr12:52,403,533...52,452,075
Ensembl chr12:52,403,529...52,452,040
JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO human cells in a mouse model RGD PMID:21037555 RGD:14392805 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase treatment ISO human cells in a mouse model RGD PMID:15014358 RGD:14392893 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ralb RAS like proto-oncogene B treatment ISO human cells in a mouse model RGD PMID:17174914 RGD:14394417 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Ralbp1 ralA binding protein 1 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Rxra retinoid X receptor alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 1:220,645,685...220,665,611
Ensembl chr 1:220,645,672...220,665,603
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 PMID:9679244 PMID:9811934 PMID:10479724 PMID:10764709 PMID:10775259 PMID:10797267 PMID:11274206 PMID:11583957 PMID:12116240 PMID:12821112 PMID:14715079 PMID:15014009 PMID:15031030 PMID:15235019 PMID:16613914 PMID:17873119 PMID:17994767 PMID:18823382 PMID:20101697 PMID:22316667 PMID:22331366 PMID:25741868 PMID:26572829 PMID:26619011 PMID:26900293 PMID:27595937 PMID:28492532 PMID:32573726 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad7 SMAD family member 7 severity ISO human cell and construct in a mouse model RGD PMID:10498890 RGD:14394510 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1591732 PMID:1631137 PMID:1644930 PMID:1673792 PMID:1683921 PMID:1686725 PMID:1737852 PMID:1915267 PMID:1918170 PMID:1978757 PMID:2046748 PMID:2113594 PMID:2259385 PMID:2826609 PMID:7565304 PMID:7651740 PMID:7707106 PMID:7732013 PMID:7750099 PMID:7783166 PMID:7881428 PMID:7887414 PMID:8023157 PMID:8062826 PMID:8080050 PMID:8099841 PMID:8118819 PMID:8164043 PMID:8242631 PMID:8336941 PMID:8364550 PMID:8401536 PMID:8423216 PMID:8425176 PMID:8479749 PMID:8527048 PMID:8550239 PMID:8633021 PMID:8688334 PMID:8718514 PMID:8825920 PMID:8829627 PMID:8869100 PMID:9020384 PMID:9049183 PMID:9096669 PMID:9157982 PMID:9218725 PMID:9242456 PMID:9268986 PMID:9290701 PMID:9364015 PMID:9407971 PMID:9472631 PMID:9525742 PMID:9546439 PMID:9569050 PMID:9572492 PMID:9598730 PMID:9627118 PMID:9632751 PMID:9635828 PMID:9662334 PMID:9667734 PMID:9825943 PMID:10064694 PMID:10229196 PMID:10411893 PMID:10432928 PMID:10519380 PMID:10567903 PMID:10589545 PMID:10616528 PMID:10713666 PMID:10761705 PMID:10797439 PMID:10864200 PMID:10871862 PMID:10914716 PMID:10922393 PMID:10949938 PMID:11051239 PMID:11051241 PMID:11139324 PMID:11180592 PMID:11313981 PMID:11370630 PMID:11429705 PMID:11479205 PMID:11590071 PMID:11593407 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11920788 PMID:11920959 PMID:12007217 PMID:12034820 PMID:12406399 PMID:12509279 PMID:12672316 PMID:12695689 PMID:12700230 PMID:12702523 PMID:12726864 PMID:12792784 PMID:12826609 PMID:12885464 PMID:12901974 PMID:12909720 PMID:12917626 PMID:14559903 PMID:14584079 PMID:14673037 PMID:15004724 PMID:15017592 PMID:15037740 PMID:15077194 PMID:15138567 PMID:15161705 PMID:15381368 PMID:15390294 PMID:15541116 PMID:15580553 PMID:15607980 PMID:15607981 PMID:15722483 PMID:15781620 PMID:15825182 PMID:15850016 PMID:15925506 PMID:15951970 PMID:15977174 PMID:15982667 PMID:15993273 PMID:16209708 PMID:16258005 PMID:16312222 PMID:16322298 PMID:16337994 PMID:16401470 PMID:16474844 PMID:16489069 PMID:16494995 PMID:16508005 PMID:16551709 PMID:16633321 PMID:16682957 PMID:16736287 PMID:16778209 PMID:16793544 PMID:16818505 PMID:16827139 PMID:16861262 PMID:17015838 PMID:17311302 PMID:17390010 PMID:17401428 PMID:17417627 PMID:17427234 PMID:17530187 PMID:17540308 PMID:17541742 PMID:17567834 PMID:17572079 PMID:17606709 PMID:17636407 PMID:17724467 PMID:17875924 PMID:18208484 PMID:18307025 PMID:18453682 PMID:18511570 PMID:18555592 PMID:18628487 PMID:18685109 PMID:18978813 PMID:18989156 PMID:19012332 PMID:19101993 PMID:19147582 PMID:19171880 PMID:19336573 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19462533 PMID:19468865 PMID:19556618 PMID:19681600 PMID:19850740 PMID:19913028 PMID:19930417 PMID:20013323 PMID:20028212 PMID:20113312 PMID:20127978 PMID:20128691 PMID:20195489 PMID:20234365 PMID:20308654 PMID:20364130 PMID:20407015 PMID:20505364 PMID:20506564 PMID:20516128 PMID:20522432 PMID:20593220 PMID:20693561 PMID:20805372 PMID:20878954 PMID:20972454 PMID:21056685 PMID:21059199 PMID:21115975 PMID:21159183 PMID:21187651 PMID:21232794 PMID:21305319 PMID:21319261 PMID:21343334 PMID:21356188 PMID:21470402 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21522129 PMID:21535297 PMID:21552135 PMID:21601526 PMID:21626334 PMID:21674059 PMID:21747090 PMID:21760960 PMID:21760996 PMID:21761402 PMID:22006311 PMID:22052707 PMID:22090360 PMID:22110706 PMID:22114072 PMID:22186996 PMID:22198284 PMID:22233476 PMID:22265402 PMID:22427690 PMID:22540896 PMID:22672556 PMID:22710932 PMID:22713868 PMID:22768918 PMID:22811390 PMID:22844452 PMID:22847613 PMID:22862161 PMID:22866089 PMID:22887876 PMID:22899716 PMID:22915647 PMID:22919068 PMID:22923379 PMID:22983585 PMID:23031740 PMID:23124483 PMID:23161690 PMID:23165212 PMID:23172776 PMID:23175693 PMID:23246812 PMID:23259501 PMID:23263379 PMID:23264849 PMID:23265383 PMID:23315175 PMID:23340422 PMID:23406775 PMID:23538418 PMID:23625637 PMID:23630318 PMID:23667202 PMID:23713777 PMID:23792586 PMID:23894400 PMID:23950206 PMID:23967324 PMID:24033266 PMID:24038938 PMID:24076587 PMID:24122735 PMID:24256616 PMID:24381225 PMID:24384472 PMID:24395441 PMID:24487413 PMID:24501221 PMID:24549055 PMID:24573247 PMID:24590827 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24702488 PMID:24728327 PMID:24744791 PMID:24763289 PMID:24766216 PMID:24810334 PMID:24835218 PMID:24940547 PMID:25119136 PMID:25123297 PMID:25157968 PMID:25293557 PMID:25294809 PMID:25339994 PMID:25428789 PMID:25433984 PMID:25503501 PMID:25504633 PMID:25525159 PMID:25584008 PMID:25584637 PMID:25619955 PMID:25634208 PMID:25669829 PMID:25691460 PMID:25741868 PMID:25757876 PMID:25787918 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:25980754 PMID:26014290 PMID:26022348 PMID:26024390 PMID:26205489 PMID:26225655 PMID:26230955 PMID:26270727 PMID:26425688 PMID:26467025 PMID:26497680 PMID:26534844 PMID:26554828 PMID:26556299 PMID:26585234 PMID:26619011 PMID:26659639 PMID:26681312 PMID:26781615 PMID:26786923 PMID:26787237 PMID:26822237 PMID:26845104 PMID:26878390 PMID:26911350 PMID:26976419 PMID:27022024 PMID:27077130 PMID:27149858 PMID:27179933 PMID:27189670 PMID:27276561 PMID:27328919 PMID:27374712 PMID:27458004 PMID:27463065 PMID:27489289 PMID:27493922 PMID:27501770 PMID:27523101 PMID:27533082 PMID:27616075 PMID:27621308 PMID:27622479 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27730344 PMID:27873457 PMID:27895058 PMID:27959731 PMID:28152038 PMID:28279309 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28476805 PMID:28477316 PMID:28492532 PMID:28724667 PMID:28802053 PMID:28861920 PMID:28915717 PMID:28975465 PMID:29025599 PMID:29070607 PMID:29126202 PMID:29324801 PMID:29416011 PMID:29470806 PMID:29478780 PMID:29489754 PMID:29581140 PMID:29752822 PMID:29753700 PMID:29979965 PMID:30076369 PMID:30128536 PMID:30216591 PMID:30224644 PMID:30297838 PMID:30299350 PMID:30306255 PMID:30311369 PMID:30327374 PMID:30352134 PMID:30450585 PMID:30630526 PMID:30675318 PMID:30709381 PMID:30720243 PMID:30816478 PMID:30840781 PMID:31016814 PMID:31206626 PMID:31300551 PMID:31775759 PMID:32000721 PMID:32295079 PMID:32401780 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr20:10,396,652...10,407,564
Ensembl chr20:10,396,621...10,407,554
JBrowse link
pancreatic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11248065 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of head of pancreas ClinVar PMID:25741868 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:9252195 RGD:8662427 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A susceptibility ISO DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 disease_progression IEP protein:increased expression:pancreas RGD PMID:21472101 RGD:9587766 NCBI chr10:55,943,467...55,970,417
Ensembl chr10:55,943,446...55,965,216
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity IEP protein:increased expression:pancreas (rat) RGD PMID:21472101 RGD:9587766 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISS
ISO
OMIM:260350
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
MouseDO
ClinVar
PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 PMID:15696205 PMID:15842656 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17332249 PMID:17384584 PMID:17704260 PMID:17910045 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19029981 PMID:19047918 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19358724 PMID:19679400 PMID:19773371 PMID:19881948 PMID:20609353 PMID:20805368 PMID:20921462 PMID:20921465 PMID:20949522 PMID:21079152 PMID:21169357 PMID:21228335 PMID:21398618 PMID:21975775 PMID:22025163 PMID:22235099 PMID:22407852 PMID:22499344 PMID:22683711 PMID:22897852 PMID:23014527 PMID:23096712 PMID:23406027 PMID:24033266 PMID:25044103 PMID:25157968 PMID:25695684 PMID:26372703 PMID:28492532 PMID:29298116 PMID:31891627 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:serum RGD PMID:28660759 RGD:24922217 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:25425965 RGD:11570510 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISS OMIM:260350 MouseDO NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:28492532 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEP mRNA:increased expression:pancreas (rat) RGD PMID:2278633 RGD:14392892 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9811458 NCBI chr18:3,134,630...3,227,702
Ensembl chr18:3,162,543...3,227,688
JBrowse link
G Smad4 SMAD family member 4 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:8653691 PMID:8898652 PMID:9679244 PMID:9811934 PMID:10479724 PMID:10764709 PMID:10775259 PMID:10797267 PMID:11274206 PMID:12821112 PMID:14715079 PMID:15014009 PMID:15031030 PMID:15235019 PMID:16152648 PMID:16613914 PMID:17873119 PMID:17994767 PMID:20101697 PMID:22331366 PMID:25741868 PMID:26619011 PMID:27595937 PMID:27978560 PMID:28135145 PMID:28492532 PMID:28528518 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11328670 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stk11 serine/threonine kinase 11 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
OMIM:260350
ClinVar
MouseDO
PMID:10362809 PMID:11430832 PMID:23399955 PMID:24307375 PMID:25186627 PMID:25741868 PMID:26056085 PMID:26467025 PMID:28135145 PMID:28492532 PMID:30287823 PMID:30982232 PMID:32566746 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Tp53 tumor protein p53 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:1565143 PMID:1565144 PMID:1683921 PMID:7732013 PMID:7887414 PMID:8164043 PMID:8423216 PMID:8513440 PMID:8825920 PMID:9047394 PMID:9242456 PMID:9569050 PMID:10411893 PMID:10797439 PMID:10864200 PMID:11101847 PMID:11139324 PMID:11479205 PMID:11782540 PMID:12007217 PMID:12619118 PMID:12672316 PMID:12826609 PMID:15004724 PMID:15381368 PMID:15390294 PMID:15607980 PMID:15607981 PMID:15951970 PMID:15977174 PMID:16401470 PMID:16489069 PMID:16682957 PMID:16818505 PMID:17540308 PMID:17606709 PMID:17636407 PMID:18391940 PMID:18511570 PMID:19127115 PMID:19556618 PMID:19881536 PMID:20113312 PMID:20128691 PMID:20407015 PMID:20516128 PMID:20689556 PMID:20693561 PMID:21187651 PMID:21305319 PMID:21343334 PMID:21484931 PMID:21519010 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22006311 PMID:22110706 PMID:22186996 PMID:22233476 PMID:22698404 PMID:22811390 PMID:22899716 PMID:22915647 PMID:23161690 PMID:23246812 PMID:23263379 PMID:23538418 PMID:23792586 PMID:24033266 PMID:24381225 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24641375 PMID:24651012 PMID:24677579 PMID:24810334 PMID:25157968 PMID:25584008 PMID:25741868 PMID:25787918 PMID:25952993 PMID:26230955 PMID:26467025 PMID:26585234 PMID:26619011 PMID:26681312 PMID:26822237 PMID:26845104 PMID:27153395 PMID:27276561 PMID:27374712 PMID:27463065 PMID:27516001 PMID:27680515 PMID:27683180 PMID:27895058 PMID:27959731 PMID:28349240 PMID:28369373 PMID:28453743 PMID:28492532 PMID:29478780 PMID:29489754 PMID:30076369 PMID:30224644 PMID:30327374 PMID:30816478 PMID:31775759 PMID:32000721 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc1 TSC complex subunit 1 ISO RGD PMID:25425965 RGD:11570510 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
pancreatic ductal adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 ISO protein:increased expression:pancreas RGD PMID:19077459 RGD:2325696 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Ccnd1 cyclin D1 severity ISO DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)
RGD PMID:25470788, PMID:22939953 RGD:13462050, RGD:13462062 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 severity ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:29735403 RGD:13781899 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:pancreatic ductal cell, nucleus (human)
DNA:amplification: : (human)
RGD PMID:12650514, PMID:17233815, PMID:27573434 RGD:13838735, RGD:13838739, RGD:13838738 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO human cells in a mouse model RGD PMID:23535601 RGD:13504844 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta susceptibility ISO RGD PMID:22264792 RGD:13838741 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Jak1 Janus kinase 1 ISO mRNA:decreased expression:pancreatic ductal cell (human) RGD PMID:28677798 RGD:13838745 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity
disease_progression
ISO protein:increased phosphorylation:pancreas (mouse) RGD PMID:28837246, PMID:23237571 RGD:14348974, RGD:14348975 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mir155 microRNA 155 disease_progression ISO RGD PMID:28198398 RGD:25314300 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Pgf placental growth factor severity ISO associated with obesity RGD PMID:26861455 RGD:14349030 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:20876794 RGD:14390130 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 severity ISO human cells in a mouse model RGD PMID:15591514 RGD:14390084 NCBI chr16:20,415,109...20,424,982
Ensembl chr16:20,416,432...20,424,980
JBrowse link
G Pld1 phospholipase D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:27713167 RGD:14392801 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Rac1 Rac family small GTPase 1 ISO mRNA:increased expression:pancreas (human)
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:23334332, PMID:21684285 RGD:14392806, RGD:14392816 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rala RAS like proto-oncogene A ISO mRNA:increased expression:pancreas (human) RGD PMID:29113235 RGD:14394418 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Smad2 SMAD family member 2 severity ISO RGD PMID:26908446 RGD:14394493 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
pancreatic ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA, protein:increased expression:pancreas RGD PMID:17481528 RGD:2325211 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO protein:decreased expression:pancreas RGD PMID:19212105 RGD:2325210 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 disease_progression ISO mRNA:increased expression:pancreas RGD PMID:17979891 RGD:2325243 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 disease_progression ISO protein:altered localization:cytoplasm RGD PMID:14997207 RGD:2325249 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO mRNA:increased expression:pancreas RGD PMID:19609859 RGD:2325659 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:19011933 RGD:2325677 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Anxa2 annexin A2 disease_progression ISO mRNA, protein:increased expression, altered localization:pancreas, plasma membrane RGD PMID:19260470, PMID:16450333 RGD:2317307, RGD:2325731 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa5 annexin A5 ISO protein:increased expression:pancreas RGD PMID:19488907 RGD:2317538 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa8 annexin A8 ISO mRNA:increased expression:pancreas RGD PMID:18223320 RGD:2325735 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Apoc1 apolipoprotein C1 ISO RGD PMID:15876873 RGD:2325793 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Arg2 arginase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreas
protein:increased expression:exocrine pancreas:
RGD PMID:19585519, PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Calr calreticulin ISO protein:increased expression:pancreatic duct RGD PMID:15289361 RGD:2326165 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Cckar cholecystokinin A receptor ISO mRNA:increased expression:pancreatic duct
protein:decreased expression:pancreas
RGD PMID:9239407, PMID:12851875 RGD:4110818, RGD:4110816 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Cckbr cholecystokinin B receptor ISO protein:decreased expression:pancreas RGD PMID:12851875 RGD:4110816 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:17420962 RGD:13462063 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd40 CD40 molecule treatment ISO protein:increased expression:dendritic cell RGD PMID:21436454, PMID:23983255, PMID:20976171 RGD:5490301, RGD:11522743, RGD:5490524 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:24389175 RGD:13782187 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO RGD PMID:17671118 RGD:8662851 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986516 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:15693851 RGD:2317592 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:29844410, PMID:19424621 RGD:9588974 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO RGD PMID:22919364 RGD:9589121 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr12:41,383,885...41,415,783
Ensembl chr12:41,385,241...41,414,754
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:228,729,842...228,759,783
Ensembl chr 1:228,732,985...228,755,866
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression: : RGD PMID:18505086 RGD:2317644 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Faslg Fas ligand ISO protein:increased expression:pancreas, liver RGD PMID:10547193, PMID:15375495 RGD:2317747, RGD:2317741 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:12717266, PMID:18704599 RGD:2317758, RGD:2317756 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fscn1 fascin actin-bundling protein 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:12109856 RGD:2317790 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Gpnmb glycoprotein nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gstp1 glutathione S-transferase pi 1 resistance ISO DNA:methylation: :
mRNA, protein:increased expression:pancreas
RGD PMID:16537562, PMID:17265526, PMID:12488200 RGD:2317809, RGD:2317806, RGD:2317811 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hdac1 histone deacetylase 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Heatr1 HEAT repeat containing 1 treatment ISO RGD PMID:26676747 RGD:10761108 NCBI chr17:66,446,135...66,488,303
Ensembl chr17:66,446,162...66,619,250
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:20098680 RGD:2317639 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein:increased expression:pancreas RGD PMID:14627343, PMID:14506643 RGD:2317649, RGD:2317652 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il4 interleukin 4 ISO RGD PMID:17942922 RGD:2317264 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO protein:increased expression:pancreas RGD PMID:17942922 RGD:2317264 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Ins2 insulin 2 ISO Glucagon/insulin RGD PMID:19571666 RGD:2317248 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jag2 jagged canonical Notch ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 6:137,711,144...137,733,331
Ensembl chr 6:137,711,155...137,733,026
JBrowse link
G Kdm2b lysine demethylase 2B severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:23321669 RGD:9588253 NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25347530 PMID:30654191 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt7 keratin 7 disease_progression ISO RGD PMID:19260470 RGD:2317307 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G L1cam L1 cell adhesion molecule severity ISO protein:increased expression:pancreas (human) RGD PMID:20162456 RGD:6483447 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment ISO human cells in mouse model RGD PMID:20179210 RGD:14348973 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO mRNA, protein:increased expression:pancreatic duct RGD PMID:15548371 RGD:2317697 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Mdm2 MDM2 proto-oncogene onset
severity
ISO DNA:snp:promoter, intron:IVS1+309T>G (human)
protein:increased expression:pancreas (human)
RGD PMID:19752772, PMID:15810085 RGD:2317414, RGD:2317416 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Men1 menin 1 ISO protein:decreased expression:pancreas RGD PMID:19170121 RGD:2317294 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:pancreatic duct (human) RGD PMID:7866999 RGD:2317530 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility ISO DNA:missense mutation:cds:p.L84F rs12917 (human)
protein:increased activity, increased expression:ductal adenocarcinoma (human)
RGD PMID:16844323, PMID:9393761 RGD:2317648, RGD:2317664 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir873 microRNA 873 ISO CTD Direct Evidence: therapeutic CTD PMID:30654191 NCBI chr 5:52,481,076...52,481,152
Ensembl chr 5:52,481,076...52,481,152
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression:pancreas RGD PMID:17377415 RGD:2325746 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:pancreas, serum
protein:increased expression:blood
RGD PMID:18706098, PMID:20332475 RGD:2325844, RGD:2325830 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msln mesothelin disease_progression ISO protein:increased secretion:serum
CTD Direct Evidence: marker/mechanism
DNA:hypomethylation:5'UTR
CTD PMID:14576474 PMID:21775916 PMID:25347530, PMID:19818733, PMID:12874021 RGD:2326055, RGD:2326065 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression, altered localization:pancreas RGD PMID:14681945, PMID:19109152, PMID:18713982 RGD:2317983, RGD:2324616, RGD:2324633 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc3 mucin 3, intestinal disease_progression ISO mRNA:increased expression:pancreas RGD PMID:12657964 RGD:2324946 NCBI chr12:22,535,663...22,584,775 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:pancreas
protein:increased expression:pancreas
RGD PMID:12657964, PMID:16049287 RGD:2324946, RGD:2324942 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming disease_progression ISO mRNA:increased expression:pancreas RGD PMID:7657125, PMID:10227724 RGD:2324986, RGD:2324907 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO mRNA:increased expression:pancreas RGD PMID:7657125 RGD:2324986 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778198 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489257 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO protein:increased expression:pancreas (human) RGD PMID:17492507 RGD:5132867 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nos2 nitric oxide synthase 2 ISO RGD PMID:12660813 RGD:2325254 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345, PMID:20484026, PMID:19028876 RGD:2325323, RGD:2325324 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Notch4 notch receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:11295066, PMID:10209957 RGD:2325660, RGD:2325663 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO protein:increased expression, alternative form:pancreas, fibroblast RGD PMID:17404500 RGD:2325781 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pax6 paired box 6 ISO protein:increased expression:pancreatic duct (human) RGD PMID:17849422 RGD:8552381 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO protein:increased expression:pancreatic duct RGD PMID:15856462 RGD:2324870 NCBI chr 9:53,120,656...53,206,520
Ensembl chr 9:53,120,656...53,206,516
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma disease_progression ISO RGD PMID:19396032 RGD:2317461 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18670639 RGD:2317185 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rnf2 ring finger protein 2 ISO protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr13:68,829,714...68,859,920
Ensembl chr13:68,830,620...68,858,809
JBrowse link
G Rxra retinoid X receptor alpha severity ISO RGD PMID:19396032 RGD:2317461 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Serpina1 serpin family A member 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:12488200 RGD:2317811 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic duct RGD PMID:19252908 RGD:2324975 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO RGD PMID:15173084 RGD:21066334 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:16826192 RGD:2324981 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26887594 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:16101174 RGD:2325019 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO mRNA:increased expresssion:pancreas RGD PMID:17114585, PMID:10547197 RGD:2317498, RGD:2317500 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:12429967, PMID:19065635 RGD:2325025, RGD:2325022 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tmprss3 transmembrane serine protease 3 ISO RGD PMID:14695172 RGD:2325152 NCBI chr20:9,910,522...9,929,705
Ensembl chr20:9,910,522...9,929,705
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc2 TSC complex subunit 2 severity ISO RGD PMID:16213898 RGD:11568674 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tymp thymidine phosphorylase disease_progression ISO RGD PMID:19760965 RGD:2325155 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation:promoter (human) RGD PMID:19065635 RGD:2325022 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
pancreatic endocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:15145354 PMID:25741868 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Daxx death-domain associated protein ISO protein:decreased expression:pancreas: RGD PMID:23954140 RGD:9587816 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:14501508 RGD:2317661 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:25741868 NCBI chr 1:192,064,586...192,088,547
Ensembl chr 1:192,064,589...192,088,520
JBrowse link
G Pgf placental growth factor disease_progression
treatment
ISO protein:increased expression:serum (human)
human cells in a mouse model
RGD PMID:23463017, PMID:26861455 RGD:14349029, RGD:14349030 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
pancreatic intraductal papillary-mucinous neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO DNA:missense mutation:cds:p.E17K (human) RGD PMID:24132918 RGD:13462042 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Tp53 tumor protein p53 ISO DNA:missense mutations: :multiple RGD PMID:28930868 RGD:14995501 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
Pancreatic Intraepithelial Neoplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas:
RGD PMID:19585519, PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO protein:increased expression:pancreas (human) RGD PMID:12882690, PMID:11751405 RGD:13462061, RGD:13464129 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Hdac1 histone deacetylase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta severity
disease_progression
ISO RGD PMID:22406536, PMID:22056382 RGD:13838740, RGD:13838742 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
pancreatic solid pseudopapillary carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:19248223 RGD:13462054 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
vipoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 menin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17961653 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16122
    disease of anatomical entity 15369
      endocrine system disease 5011
        endocrine gland cancer 1458
          pancreatic cancer 380
            Adult Pancreatic Cancer 1
            Familial Pancreatic Carcinoma 1
            Gastro-Enteropancreatic Neuroendocrine Tumor 15
            Melanoma-Pancreatic Cancer Syndrome 1
            Pancreatic Intraepithelial Neoplasia 7
            Pheochromocytoma Islet Cell Tumor Syndrome 0
            islet cell tumor + 22
            malignant exocrine pancreas neoplasm + 2
            non-functioning pancreatic endocrine tumor + 2
            pancreas lymphoma + 0
            pancreas sarcoma 0
            pancreatic carcinoma + 155
            pancreatic endocrine carcinoma + 12
            pancreatic squamous cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 16122
    disease of cellular proliferation 5907
      cancer 3745
        organ system cancer 3596
          endocrine gland cancer 1458
            pancreatic cancer 380
              Adult Pancreatic Cancer 1
              Familial Pancreatic Carcinoma 1
              Gastro-Enteropancreatic Neuroendocrine Tumor 15
              Melanoma-Pancreatic Cancer Syndrome 1
              Pancreatic Intraepithelial Neoplasia 7
              Pheochromocytoma Islet Cell Tumor Syndrome 0
              islet cell tumor + 22
              malignant exocrine pancreas neoplasm + 2
              non-functioning pancreatic endocrine tumor + 2
              pancreas lymphoma + 0
              pancreas sarcoma 0
              pancreatic carcinoma + 155
              pancreatic endocrine carcinoma + 12
              pancreatic squamous cell carcinoma 0
paths to the root