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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:cryptosporidiosis
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Accession:DOID:1733 term browser browse the term
Definition:A coccidiosis that involves a parasitic protozoan infection of the intestine of humans and a wide range of animals caused by Cryptosporidium species, through contaminated water and food, The symptoms include watery diarrhea, dehydration, weight loss, abdominal pain, fever, nausea and vomiting. Cryptosporidium infections have also been found in other digestive tract organs, the lungs, and conjunctiva. Immunocompromised persons are at greater risk of developing the infection. (DO)
Synonyms:exact_synonym: Cryptosporidioses;   cryptosporidial gastroenteritis;   infection by Cryptosporidium;   intestinal cryptosporidiosis
 primary_id: MESH:D003457
 xref: GARD:6219;   ICD10CM:A07.2;   ICD9CM:007.4;   NCI:C128408
For additional species annotation, visit the Alliance of Genome Resources.


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cryptosporidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:polymorphisms, haplotype:promoter,exon: RGD PMID:19827946 RGD:12910843 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression:ileum RGD PMID:25838265 RGD:40925950 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97543
    Animal Diseases 1397
      Parasitic Diseases, Animal 22
        Protozoan Infections, Animal 18
          cryptosporidiosis 2
Path 2
Term Annotations click to browse term
  disease 97543
    disease by infectious agent 4420
      parasitic infectious disease 556
        parasitic protozoa infectious disease 367
          coccidiosis 27
            cryptosporidiosis 2
paths to the root