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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

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Accession:DOID:1731 term browser browse the term
Definition:A primary systemic mycosis that results in systemic fungal infection, has_material_basis_in Histoplasma capsulatum var capsulatum or has_material_basis_in Histoplasma capsulatum var duboisii, transmitted_by airborne spores and has_symptom nonproductive cough, has_symptom headache, has_symptom loss of appetite and has_symptom muscle pains. (DO)
Synonyms:exact_synonym: histoplasmoses
 primary_id: MESH:D006660
 xref: ICD10CM:B39;   ICD9CM:115;   NCI:C34977;   NCI:C77201
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
histoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule ISO protein:increased expression:macrophage, dendritic cell, lymphocyte, splenocytes, RGD PMID:18268348 RGD:40822806 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Il17a interleukin 17A ISO mRNA, protein:increased expression:lung (mouse) RGD PMID:19469707 RGD:9068939 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:18268348 RGD:40822806 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 ISO protein:increased expression:macrophage, dendritic cell RGD PMID:18268348 RGD:40822806 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938
JBrowse link
G RT1-CE13 RT1 class I, locus CE13 ISO Presumed Ocular Histoplasmosis Syndrome; DNA:polymorphisms:cds:HLA-B7 (human) RGD PMID:14522093 RGD:7364917 NCBI chr20:3,314,984...3,318,037 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18145
    disease by infectious agent 2136
      Bacterial Infections and Mycoses 992
        fungal infectious disease 143
          systemic mycosis 135
            primary systemic mycosis 21
              histoplasmosis 5
                African histoplasmosis 0
                American histoplasmosis 0
                Presumed Ocular Histoplasmosis Syndrome 0
                histoplasmosis meningitis 0
                histoplasmosis pericarditis 0
paths to the root