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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:rheumatic disease
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Accession:DOID:1575 term browser browse the term
Definition:Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
Synonyms:exact_synonym: rheumatic diseases;   rheumatism
 primary_id: MESH:D012216
For additional species annotation, visit the Alliance of Genome Resources.


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adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hgf hepatocyte growth factor ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
Beukes hip dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH4orf47 chromosome unknown C4orf47 homolog ISO ClinVar Annotator: match by term: Hip dysplasia, beukes type ClinVar PMID:2389793 PMID:21228277 PMID:26428751 NCBI chrNW_004955403:23,617,764...23,634,689
Ensembl chrNW_004955403:23,619,399...23,634,731
JBrowse link
G Ufsp2 UFM1 specific peptidase 2 ISO OMIM NCBI chrNW_004955403:23,634,967...23,655,429
Ensembl chrNW_004955403:23,634,924...23,655,429
JBrowse link
CREST syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpc centromere protein C ISO associated with Anticentromere antibody positivity RGD PMID:25220385 RGD:27372886 NCBI chrNW_004955447:5,345,617...5,406,889
Ensembl chrNW_004955447:5,345,896...5,406,730
JBrowse link
G Fbn1 fibrillin 1 ISO RGD PMID:10395706 RGD:12910471 NCBI chrNW_004955409:5,281,603...5,502,547
Ensembl chrNW_004955409:5,281,603...5,504,761
JBrowse link
diffuse scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing severity ISO protein:decreased expression:serum RGD PMID:21615510 RGD:8694418 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Agt angiotensinogen ISO protein:increased expression:serum RGD PMID:14730619 RGD:8548886 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Bank1 B cell scaffold protein with ankyrin repeats 1 susceptibility ISO DNA:SNPs: :rs10516487,rs17266594,rs3733197(human) RGD PMID:19815934 RGD:9684975 NCBI chrNW_004955496:6,267,618...6,511,195
Ensembl chrNW_004955496:6,267,551...6,470,948
JBrowse link
G Cav1 caveolin 1 susceptibility
no_association
ISO DNA:SNPs:intron, 3' utr: (rs729949, rs3815412, rs9920) (human)
DNA:SNPs:enhancer, intron:multiple
RGD PMID:22402147 RGD:8661768 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:serum RGD PMID:9034992 RGD:5684371 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il13 interleukin 13 ISO DNA:SNPs:5' utr, enhancer: (rs1800925, rs2243204) (human) RGD PMID:16832637 RGD:5684369 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:20338043 RGD:12792275 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 susceptibility ISO DNA:missense mutation:cds:p.F196S (rs1059702) (human) RGD PMID:21898345 RGD:7495782 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Stat4 signal transducer and activator of transcription 4 no_association
susceptibility
ISO DNA:SNP:intron: (rs7574865) (human)
DNA:SNP:intron: (rs3821236) (human)
DNA:SNP:introns: (rs7574865, rs10168266) (human)
RGD PMID:19286670 PMID:23755762 RGD:8661701 RGD:8661714 NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chrNW_004955437:1,504,549...1,511,110
Ensembl chrNW_004955437:1,504,947...1,511,097
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chrNW_004955437:1,480,217...1,499,032 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27228633 NCBI chrNW_004955419:26,490,899...26,546,349
Ensembl chrNW_004955419:26,490,899...26,547,017
JBrowse link
G Tlr2 toll like receptor 2 disease_progression ISO DNA:polymorphism:cds:p.P631H(rs5743704)(human) RGD PMID:21905008 RGD:8553044 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:16906373 RGD:10042980 NCBI chrNW_004955463:7,495,243...7,633,532
Ensembl chrNW_004955463:7,525,100...7,633,596
JBrowse link
Digital Arthropathy-Brachydactyly, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel subfamily V member 4 ISO OMIM NCBI chrNW_004955455:8,744,865...8,781,644
Ensembl chrNW_004955455:8,744,176...8,783,741
JBrowse link
erythema nodosum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G Cfb complement factor B ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chrNW_004955437:461,235...466,908 JBrowse link
G Lta lymphotoxin alpha ISO associated with Sarcoidosis;DNA:polymorphism:intron RGD PMID:19225544 RGD:8548773 NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with Inflammatory Bowel Diseases;DNA:polymorphisms: :-1031T>C(human) RGD PMID:12198697 RGD:7364926 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Vdr vitamin D receptor susceptibility ISO associated with Behcet Syndrome;DNA:polymorphism: : rs7975232(human) RGD PMID:24880677 RGD:13217417 NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048
JBrowse link
Familial Osteochondritis Dissecans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan ISO OMIM NCBI chrNW_004955416:16,125,536...16,186,046 JBrowse link
fibromyalgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase ISO protein:decreased activity:mononuclear cell: RGD PMID:22532869 RGD:9479066 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Comt catechol-O-methyltransferase severity ISO DNA:polymorphism:cds:p.V158M(human) RGD PMID:24762091 RGD:13450944 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
JBrowse link
G Il1rn interleukin 1 receptor antagonist severity ISO protein:increased expression:serum (human) RGD PMID:10341365 RGD:8549787 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
Hand Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 no_association ISO DNA:SNPs:exons: (rs2077647, rs1801132) (human) RGD PMID:19884274 RGD:10045830 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G Esr2 estrogen receptor 2 no_association ISO DNA:SNPs:introns: (rs1256034, rs1256059, rs944460) (human) RGD PMID:19884274 RGD:10045830 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Il4 interleukin 4 no_association ISO DNA:SNPs:promoter, 5' utr, intron:multiple RGD PMID:20219689 RGD:10402786 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor no_association ISO DNA:SNPs:promoter, exons:multiple RGD PMID:20219689 RGD:10402786 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Matn3 matrilin 3 ISO ClinVar Annotator: match by term: HAND OSTEOARTHRITIS ClinVar PMID:12736871 PMID:14729835 PMID:28492532 NCBI chrNW_004955469:2,548,443...2,568,497
Ensembl chrNW_004955469:2,548,443...2,568,497
JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955501:6,168,083...6,218,934
Ensembl chrNW_004955501:6,164,152...6,218,967
JBrowse link
G Acrbp acrosin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:4,251,608...4,262,095 JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955433:8,362,957...8,428,773
Ensembl chrNW_004955433:8,362,756...8,426,997
JBrowse link
G Ankrd9 ankyrin repeat domain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955538:1,735,898...1,739,827 JBrowse link
G Aopep aminopeptidase O (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955422:21,680,488...22,020,935 JBrowse link
G Aqp9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955450:16,253,706...16,346,602
Ensembl chrNW_004955450:16,253,571...16,302,657
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955474:680,212...689,021
Ensembl chrNW_004955474:680,204...689,088
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955461:4,813,228...5,083,548
Ensembl chrNW_004955461:4,811,069...5,133,257
JBrowse link
G Avl9 AVL9 cell migration associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955617:61,225...129,222
Ensembl chrNW_004955617:61,225...113,652
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955445:8,471,684...8,559,672
Ensembl chrNW_004955445:8,534,220...8,559,672
JBrowse link
G Bend2 BEN domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955519:104,726...155,418 JBrowse link
G Btg1 BTG anti-proliferation factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955405:29,206,889...29,209,407
Ensembl chrNW_004955405:29,206,889...29,209,407
JBrowse link
G Btg3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955407:18,927,211...18,939,576
Ensembl chrNW_004955407:18,927,211...18,941,424
JBrowse link
G C8b complement C8 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chrNW_004955464:2,754,655...2,796,423 JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955472:7,299,092...7,337,591
Ensembl chrNW_004955472:7,310,788...7,337,735
JBrowse link
G Cald1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955494:7,578,162...7,675,558 JBrowse link
G Camsap1 calmodulin regulated spectrin associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955513:4,649,816...4,704,282
Ensembl chrNW_004955513:4,667,292...4,705,910
JBrowse link
G Cd14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224
JBrowse link
G Cd83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955465:676,006...692,770
Ensembl chrNW_004955465:674,168...693,353
JBrowse link
G Cd8b CD8b molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955424:922,916...939,469 JBrowse link
G Ciita class II major histocompatibility complex transactivator no_association
susceptibility
ISO DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:polymorphism:exon:1614G>C (human)
RGD PMID:16426246 PMID:17661914 RGD:5491187 RGD:5491189 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624
JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
JBrowse link
G Cmtm2 CKLF like MARVEL transmembrane domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955433:23,140,178...23,149,252 JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955462:2,491,504...2,547,587
Ensembl chrNW_004955462:2,491,504...2,536,385
JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460
JBrowse link
G Cttn cortactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955422:15,838,036...15,874,067
Ensembl chrNW_004955422:15,835,145...15,874,108
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 PMID:26387944 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955432:29,925...254,327
Ensembl chrNW_004955432:29,197...254,379
JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955458:5,232,979...5,238,513
Ensembl chrNW_004955458:5,232,979...5,238,513
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381
JBrowse link
G Dusp2 dual specificity phosphatase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955470:3,735,224...3,737,667
Ensembl chrNW_004955470:3,735,871...3,737,568
JBrowse link
G Dusp4 dual specificity phosphatase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955463:5,778,945...5,794,282
Ensembl chrNW_004955463:5,778,700...5,794,282
JBrowse link
G Dysf dysferlin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955424:13,756,130...13,970,437
Ensembl chrNW_004955424:13,756,130...13,970,436
JBrowse link
G Egf epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955496:325,954...401,430
Ensembl chrNW_004955496:328,075...401,569
JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007
JBrowse link
G Elf2 E74 like ETS transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955428:4,458,962...4,550,783
Ensembl chrNW_004955428:4,479,913...4,550,783
JBrowse link
G Etnk1 ethanolamine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:18,036,646...18,094,875
Ensembl chrNW_004955413:18,036,646...18,089,370
JBrowse link
G Etv6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:8,698,412...8,912,011
Ensembl chrNW_004955413:8,698,415...8,909,299
JBrowse link
G Fam20a FAM20A golgi associated secretory pathway pseudokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955478:4,182,568...4,236,819
Ensembl chrNW_004955478:4,182,568...4,236,819
JBrowse link
G Faxdc2 fatty acid hydroxylase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955408:9,084,039...9,102,525
Ensembl chrNW_004955408:9,084,803...9,102,526
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955414:18,343,832...18,597,675
Ensembl chrNW_004955414:18,343,832...18,597,675
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955555:2,438,864...2,445,846
Ensembl chrNW_004955555:2,438,864...2,445,846
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955469:10,297,179...10,319,180
Ensembl chrNW_004955469:10,297,179...10,319,180
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955421:16,595,445...17,075,923 JBrowse link
G Gadd45a growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955423:23,656,516...23,658,367
Ensembl chrNW_004955423:23,656,458...23,658,367
JBrowse link
G Gmpr guanosine monophosphate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955483:9,559,079...9,608,807
Ensembl chrNW_004955483:9,559,079...9,608,953
JBrowse link
G Gng11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955432:10,664,251...10,668,749
Ensembl chrNW_004955432:10,664,170...10,668,953
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955442:18,359,664...18,360,979
Ensembl chrNW_004955442:18,359,664...18,360,979
JBrowse link
G Hbegf heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955418:259,860...321,340
Ensembl chrNW_004955418:309,096...321,387
JBrowse link
G Herpud2 HERPUD family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955460:7,461,025...7,495,242
Ensembl chrNW_004955460:7,461,025...7,497,495
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hspa6 heat shock protein family A (Hsp70) member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955462:14,723,990...14,726,420 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chrNW_004955403:3,062,724...3,073,419
Ensembl chrNW_004955403:3,063,133...3,073,419
JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il2 interleukin 2 ISO protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Itga2b integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955451:17,381,323...17,392,122
Ensembl chrNW_004955451:17,382,779...17,391,859
JBrowse link
G Itgb5 integrin subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955427:23,851,475...23,952,211
Ensembl chrNW_004955427:23,850,261...23,939,950
JBrowse link
G Jmjd1c jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955425:16,343,314...16,552,552
Ensembl chrNW_004955425:16,344,141...16,493,527
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Kcnj15 potassium inwardly rectifying channel subfamily J member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955407:37,261,892...37,313,484
Ensembl chrNW_004955407:37,267,926...37,313,484
JBrowse link
G Klf4 Kruppel like factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955419:19,280,311...19,284,097
Ensembl chrNW_004955419:19,280,235...19,285,174
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758
JBrowse link
G Lacc1 laccase domain containing 1 ISO OMIM NCBI chrNW_004955518:1,794,067...1,809,150 JBrowse link
G LOC102003714 chromosome unknown open reading frame, human C2orf88 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955403:8,797,416...8,847,431 JBrowse link
G Lpp LIM domain containing preferred translocation partner in lipoma ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955420:19,014,398...19,634,102
Ensembl chrNW_004955420:19,014,398...19,478,472
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955460:9,340,728...9,672,478
Ensembl chrNW_004955460:9,340,681...9,672,134
JBrowse link
G Maff MAF bZIP transcription factor F ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:24,494,326...24,504,728 JBrowse link
G Maml2 mastermind like transcriptional coactivator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955412:849,367...1,038,341
Ensembl chrNW_004955412:847,977...952,259
JBrowse link
G Map2 microtubule associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020
JBrowse link
G Mbl2 mannose binding lectin 2 ISO RGD PMID:18334024 RGD:12910845 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
JBrowse link
G Mex3c mex-3 RNA binding family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955402:36,049,461...36,065,765
Ensembl chrNW_004955402:36,047,856...36,065,771
JBrowse link
G Msn moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955475:5,301,856...5,370,378
Ensembl chrNW_004955475:5,301,910...5,370,691
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955540:3,204,357...3,346,026
Ensembl chrNW_004955540:3,204,367...3,346,026
JBrowse link
G Myzap myocardial zonula adherens protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955450:16,664,673...16,730,769 JBrowse link
G Ndel1 nudE neurodevelopment protein 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955467:8,432,806...8,486,563
Ensembl chrNW_004955467:8,432,806...8,468,155
JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955449:16,928,780...16,944,536
Ensembl chrNW_004955449:16,937,794...16,945,731
JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955463:8,009,436...9,037,116
Ensembl chrNW_004955463:8,009,530...9,037,116
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955455:4,510,711...4,515,282
Ensembl chrNW_004955455:4,511,769...4,514,633
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955413:28,119,769...28,209,258
Ensembl chrNW_004955413:28,116,961...28,140,810
JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1B, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955509:4,896,208...4,990,101
Ensembl chrNW_004955509:4,896,190...4,990,149
JBrowse link
G Per1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955467:8,798,436...8,813,369
Ensembl chrNW_004955467:8,797,912...8,813,365
JBrowse link
G Pgm5 phosphoglucomutase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955434:4,489,054...4,670,879
Ensembl chrNW_004955434:4,489,054...4,670,161
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324
JBrowse link
G Plk2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955446:9,671,090...9,676,956
Ensembl chrNW_004955446:9,671,090...9,677,188
JBrowse link
G Plod2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955474:11,392,163...11,473,918
Ensembl chrNW_004955474:11,392,163...11,475,508
JBrowse link
G Pros1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955407:3,514,900...3,566,165
Ensembl chrNW_004955407:3,535,388...3,565,058
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G R3hdm2 R3H domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955458:4,981,967...5,127,409
Ensembl chrNW_004955458:4,981,968...5,127,390
JBrowse link
G Rasgef1b RasGEF domain family member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955433:5,605,548...6,388,880
Ensembl chrNW_004955433:5,605,548...6,176,875
JBrowse link
G Rbm47 RNA binding motif protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955443:6,940,523...7,100,130
Ensembl chrNW_004955443:6,940,523...7,100,130
JBrowse link
G Rere arginine-glutamic acid dipeptide repeats ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955486:4,303,573...4,695,800
Ensembl chrNW_004955486:4,443,723...4,695,800
JBrowse link
G Rhobtb1 Rho related BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955425:14,299,128...14,366,732
Ensembl chrNW_004955425:14,299,035...14,360,759
JBrowse link
G Rnf103 ring finger protein 103 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955424:1,097,981...1,161,267
Ensembl chrNW_004955424:1,097,981...1,117,844
JBrowse link
G Selp selectin P severity ISO protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
JBrowse link
G Sh2d2a SH2 domain containing 2A ISO DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chrNW_004955545:2,881,954...2,891,021
Ensembl chrNW_004955545:2,881,563...2,891,509
JBrowse link
G Sh3bgrl2 SH3 domain binding glutamate rich protein like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955502:7,517,466...7,575,560
Ensembl chrNW_004955502:7,517,461...7,575,951
JBrowse link
G Sik1 salt inducible kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955407:38,739,062...38,749,293 JBrowse link
G Sipa1l1 signal induced proliferation associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955523:3,545,807...3,908,329
Ensembl chrNW_004955523:3,545,708...3,797,572
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10857800 PMID:16597321 RGD:5684977 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Slc26a2 solute carrier family 26 member 2 susceptibility ISO DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chrNW_004955415:4,540,302...4,556,360
Ensembl chrNW_004955415:4,540,302...4,556,360
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
JBrowse link
G Stab1 stabilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955430:2,491,960...2,518,063
Ensembl chrNW_004955430:2,491,974...2,518,063
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Stim1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955414:19,652,990...19,849,353
Ensembl chrNW_004955414:19,652,990...19,847,964
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134
JBrowse link
G Tfdp1 transcription factor Dp-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955404:371,905...408,441
Ensembl chrNW_004955404:368,793...408,930
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955403:10,925,155...11,004,229
Ensembl chrNW_004955403:10,924,893...11,004,284
JBrowse link
G Thbd thrombomodulin ISO protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955440:16,915,952...16,944,375
Ensembl chrNW_004955440:16,916,055...16,944,190
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955408:38,872,305...38,986,932
Ensembl chrNW_004955408:38,872,007...38,990,650
JBrowse link
G Tnik TRAF2 and NCK interacting kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955420:1,166,340...1,542,712
Ensembl chrNW_004955420:1,166,340...1,542,326
JBrowse link
G Treml1 triggering receptor expressed on myeloid cells like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955437:7,773,279...7,778,197
Ensembl chrNW_004955437:7,773,612...7,777,575
JBrowse link
G Ttll5 tubulin tyrosine ligase like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955612:109,742...351,255
Ensembl chrNW_004955612:109,743...353,918
JBrowse link
G Ube2e1 ubiquitin conjugating enzyme E2 E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955430:15,648,736...15,734,767
Ensembl chrNW_004955430:15,648,476...15,734,767
JBrowse link
G Ube3c ubiquitin protein ligase E3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955579:127,535...207,522
Ensembl chrNW_004955579:127,533...207,522
JBrowse link
G Uhrf1bp1l UHRF1 binding protein 1 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955405:35,814,803...35,935,553
Ensembl chrNW_004955405:35,832,944...35,935,266
JBrowse link
G Wasf3 WASP family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955497:6,100,633...6,190,639
Ensembl chrNW_004955497:6,102,909...6,190,770
JBrowse link
G Wwox WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955522:1,265,732...2,185,372
Ensembl chrNW_004955522:1,265,404...2,184,562
JBrowse link
G Zfand3 zinc finger AN1-type containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955437:5,158,936...5,356,243
Ensembl chrNW_004955437:5,157,309...5,356,290
JBrowse link
G Zfc3h1 zinc finger C3H1-type containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chrNW_004955405:11,598,802...11,647,135
Ensembl chrNW_004955405:11,596,399...11,647,135
JBrowse link
Knee Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 disease_progression ISO protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chrNW_004955450:14,545,586...14,574,161
Ensembl chrNW_004955450:14,512,381...14,574,696
JBrowse link
G Anxa5 annexin A5 disease_progression ISO protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chrNW_004955428:18,873,782...18,907,955
Ensembl chrNW_004955428:18,873,782...18,907,955
JBrowse link
G Ar androgen receptor ISO DNA:repeat:exon:c.172(CAG)8-34 (human) RGD PMID:16098017 RGD:10043199 NCBI chrNW_004955475:7,013,960...7,192,473
Ensembl chrNW_004955475:7,013,960...7,186,069
JBrowse link
G Aspn asporin severity ISO DNA:repeats:exon:
mRNA:increased expression:cartilage:
RGD PMID:15640800 RGD:9684965 NCBI chrNW_004955515:5,322,074...5,345,715
Ensembl chrNW_004955515:5,321,943...5,345,894
JBrowse link
G B2m beta-2-microglobulin ISO protein:increased expression:serum RGD PMID:18795399 RGD:6482710 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO RGD PMID:21387139 PMID:22294259 RGD:6483563 RGD:6483595 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:dorsal root ganglion: RGD PMID:23185004 RGD:8661785 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Cd36 CD36 molecule disease_progression ISO RGD PMID:19342682 PMID:21765106 RGD:6893494 RGD:6893565 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Ctnnb1 catenin beta 1 ISO protein:increased expression:cartilage: RGD PMID:22702043 RGD:10395278 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO RGD PMID:31258642 RGD:150519887 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 severity ISO mRNA,protein:increased expression:fat pad: RGD PMID:21765106 RGD:6893494 NCBI chrNW_004955414:16,059,781...16,089,727
Ensembl chrNW_004955414:16,059,781...16,089,727
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO RGD PMID:20131282 RGD:6907382 NCBI chrNW_004955425:7,353,964...7,357,599 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:25435813 RGD:13506963 NCBI chrNW_004955493:8,661,317...8,663,190 JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO protein:increased expression:serum: RGD PMID:22275171 RGD:10401792 NCBI chrNW_004955424:27,181,717...27,240,067
Ensembl chrNW_004955424:27,181,099...27,240,446
JBrowse link
G Epas1 endothelial PAS domain protein 1 no_association ISO DNA:SNP:5' utr: (rs17039192) (human) RGD PMID:20495570 PMID:22247019 RGD:10395367 RGD:10395368 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:25422652 RGD:10400892 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G Esr1 estrogen receptor 1 ISO DNA:repeat:promoter:-1174(TA)9-25 (human)
DNA:SNP:cds:c.1782G>A (rs2228480) (human)
DNA:SNPs:intron: (rs2234693, rs9340799) (human)
DNA:polymorphisms, haplotype:intron, exon
RGD PMID:15380041 PMID:16098017 PMID:20128071 PMID:24772413 RGD:10043199 RGD:10045829 RGD:10045835 RGD:10045840 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G Esr2 estrogen receptor 2 ISO DNA:repeat:intron:c.1092+3607(CA)13-27 (human) RGD PMID:16098017 RGD:10043199 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21041276 RGD:5147774 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 treatment ISO RGD PMID:27159076 RGD:11568056 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590
JBrowse link
G Gdf5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955422:25,992,081...25,997,122
Ensembl chrNW_004955422:25,992,081...25,997,122
JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:increased expression:synovial fluid RGD PMID:16289733 RGD:10401830 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
G Hmgb1 high mobility group box 1 severity ISO mRNA:decreased expression:articular cartilage
protein:increased expression:synovial fluid
RGD PMID:19139395 PMID:21968272 RGD:10402061 RGD:10402184 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
JBrowse link
G Hmgb2 high mobility group box 2 severity ISO mRNA:decreased expression:articular cartilage RGD PMID:19139395 RGD:10402184 NCBI chrNW_004955403:33,656,314...33,659,115
Ensembl chrNW_004955403:33,656,300...33,659,428
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO mRNA:increased expression:tibial plateaux (mouse)
mRNA:decreased expression:blood (human)
RGD PMID:9497939 PMID:16139532 RGD:10412655 RGD:10429075 NCBI chrNW_004955538:1,469,544...1,475,010 JBrowse link
G Igf1 insulin like growth factor 1 severity
disease_progression
ISO protein:decreased expression:plasma (rat)
mRNA:increased expression:meniscus:
RGD PMID:8461919 PMID:9497937 PMID:17133593 PMID:20633672 RGD:10003130 RGD:10045862 RGD:10045868 RGD:10046057 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:8948288 RGD:10045874 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:cartilage cell: RGD PMID:9034998 PMID:9497937 PMID:24534736 RGD:10045944 RGD:10045946 RGD:10046057 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Il2 interleukin 2 severity ISO protein:increased expression:synovial fluid: RGD PMID:22035391 RGD:5687147 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:repeat:intron: (rs8179190) (human) RGD PMID:18182309 PMID:24406619 RGD:10402787 RGD:2317291 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Kl klotho susceptibility ISO DNA:SNPs:promoter,exon:395G>A,2998C>T(human) RGD PMID:18465812 RGD:10403041 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215
JBrowse link
G Lep leptin ISO protein:decreased expression:serum: RGD PMID:23575542 RGD:10411887 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:CDS:668A>G (human)
protein:increased expression:serum
RGD PMID:23575542 RGD:10411887 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
JBrowse link
G LOC102023780 aromatase ISO DNA:SNP:intron, 5' utr: (rs1062033) (human) RGD PMID:20417295 RGD:10045662 NCBI chrNW_004955409:3,198,622...3,313,072
Ensembl chrNW_004955409:3,266,233...3,313,142
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 susceptibility ISO DNA:snp:promoter:g.-2820G>A (rs10980705) (human) RGD PMID:18325907 RGD:10054291 NCBI chrNW_004955419:16,190,109...16,324,702
Ensembl chrNW_004955419:16,191,244...16,325,602
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955441:1,405,340...1,626,668
Ensembl chrNW_004955441:1,232,041...1,627,470
JBrowse link
G Mmp13 matrix metallopeptidase 13 ameliorates ISO RGD PMID:31258642 RGD:150519887 NCBI chrNW_004955412:6,106,994...6,118,760
Ensembl chrNW_004955412:6,106,994...6,118,760
JBrowse link
G Penk proenkephalin treatment ISO RGD PMID:21928671 RGD:10003115 NCBI chrNW_004955454:15,425,712...15,426,685
Ensembl chrNW_004955454:15,426,017...15,426,685
JBrowse link
G Ptges prostaglandin E synthase ISO RGD PMID:17530714 RGD:2300093 NCBI chrNW_004955445:10,053,745...10,056,981 JBrowse link
G Sbno1 strawberry notch homolog 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955482:5,519,165...5,571,416
Ensembl chrNW_004955482:5,528,652...5,576,234
JBrowse link
G Slc26a2 solute carrier family 26 member 2 susceptibility ISO DNA:deletion:promoter:-716_-713del4A(human) RGD PMID:11558903 RGD:13208866 NCBI chrNW_004955415:4,540,302...4,556,360
Ensembl chrNW_004955415:4,540,302...4,556,360
JBrowse link
G Tgfa transforming growth factor alpha ISO protein:increased expression:cartilage
mRNA:increased expression:cartilage
RGD PMID:17968906 RGD:2317486 NCBI chrNW_004955424:14,616,390...14,709,723
Ensembl chrNW_004955424:14,616,259...14,710,183
JBrowse link
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955484:6,853,820...6,967,261
Ensembl chrNW_004955484:6,851,307...6,967,261
JBrowse link
limited scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 susceptibility
no_association
ISO DNA:SNPs:enhancer, intron:multiple
DNA:SNPs:3' utr, intron: (rs9920, rs729949, rs3815412) (human)
RGD PMID:22402147 RGD:8661768 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:skin: RGD PMID:12925209 RGD:8661733 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Fas Fas cell surface death receptor ISO RGD PMID:17102953 RGD:12903974 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand ISO RGD PMID:17102953 RGD:12903974 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:polymorphism::-384T>G(human) RGD PMID:17444587 RGD:4142872 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:20808962 RGD:4892610 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Pgf placental growth factor ISO protein:increased expression:plasma RGD PMID:22461185 RGD:6483571 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
JBrowse link
G Serpine1 serpin family E member 1 ISO mRNA,protein:increased expression:skin: RGD PMID:15730388 RGD:13208597 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Stat4 signal transducer and activator of transcription 4 susceptibility
no_association
ISO DNA:SNP:intron: (rs7574865) (human)
DNA:SNPs:introns: (rs10168266, rs3821236) (human)
RGD PMID:19286670 PMID:23755762 RGD:8661701 RGD:8661714 NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chrNW_004955437:1,480,217...1,499,032 JBrowse link
Lipodermatosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO mRNA:increased expression:dermis RGD PMID:15727634 RGD:5688298 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
localized scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO mRNA,protein:increased expression:skin: RGD PMID:15803328 RGD:8662838 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15863969 NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
JBrowse link
G Hgf hepatocyte growth factor treatment ISO RGD PMID:14712301 RGD:8548627 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:7916356 RGD:8158116 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12920362 RGD:8549537 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15726408 NCBI chrNW_004955545:2,290,076...2,310,982
Ensembl chrNW_004955545:2,290,037...2,313,033
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO RGD PMID:7510487 RGD:7394847 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9843018 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
nodular nonsuppurative panniculitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102021597 alpha-1-antiproteinase S-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:3259592 PMID:6982619 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955402:34,857,317...34,885,169
Ensembl chrNW_004955402:34,857,317...34,885,169
JBrowse link
G Acan aggrecan treatment ISO RGD PMID:21853458 PMID:22833446 RGD:11570535 RGD:11570544 NCBI chrNW_004955416:16,125,536...16,186,046 JBrowse link
G Aco1 aconitase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955472:3,141,473...3,170,959
Ensembl chrNW_004955472:3,141,257...3,170,959
JBrowse link
G Actb actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955460:10,358,100...10,361,585
Ensembl chrNW_004955460:10,356,699...10,361,585
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955477:3,917,637...4,263,529
Ensembl chrNW_004955477:3,922,644...4,263,296
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 ISO RGD PMID:15818704 RGD:1559176 NCBI chrNW_004955545:1,545,532...1,555,826
Ensembl chrNW_004955545:1,545,635...1,555,614
JBrowse link
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif 14 ISO DNA:missense mutation:cds: (rs4747096) (human) RGD PMID:18790654 RGD:6771189 NCBI chrNW_004955437:20,592,278...20,664,075
Ensembl chrNW_004955437:20,593,739...20,664,075
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif 4 treatment ISO associated with Bone Diseases, Metabolic RGD PMID:22432033 RGD:10043110 NCBI chrNW_004955468:12,950,333...12,958,599
Ensembl chrNW_004955468:12,951,155...12,958,212
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 treatment
no_association
disease_progression
ISO DNA:missense mutations:exon: (rs226794, rs2830585) (human)
DNA:missense mutation:exon:p.R614H (human)
protein:alternative form:synovium
mRNA:increased expression:cartilage
associated with Bone Diseases, Metabolic
RGD PMID:11801682 PMID:17530714 PMID:18240210 PMID:22084394 PMID:22432033 More... RGD:10003165 RGD:10043101 RGD:10043102 RGD:10043103 RGD:10043105 RGD:10043106 RGD:10043107 RGD:10043110 RGD:2300093 NCBI chrNW_004955407:26,597,165...26,643,972
Ensembl chrNW_004955407:26,603,479...26,643,103
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955586:359,573...477,277
Ensembl chrNW_004955586:359,567...479,325
JBrowse link
G Ager advanced glycosylation end-product specific receptor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16948116 PMID:23894457 RGD:8695985 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Ak4 adenylate kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955423:25,395,086...25,402,324
Ensembl chrNW_004955423:25,395,836...25,427,474
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24728293 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180
JBrowse link
G Aspn asporin susceptibility
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:repeats:exon:
OMIM
CTD
RGD
PMID:16542493 RGD:9684966 NCBI chrNW_004955515:5,322,074...5,345,715
Ensembl chrNW_004955515:5,321,943...5,345,894
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955555:869,508...892,510 JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955403:43,860,811...43,886,398
Ensembl chrNW_004955403:43,860,728...43,886,732
JBrowse link
G Bad BCL2 associated agonist of cell death ISO RGD PMID:19217321 RGD:10053643 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
JBrowse link
G Bag6 BAG cochaperone 6 susceptibility ISO DNA:SNP: :rs3117582(human) RGD PMID:25231575 RGD:14390133 NCBI chrNW_004955437:176,848...188,243
Ensembl chrNW_004955437:176,797...188,003
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO protein:increased expression:chondrocyte RGD PMID:16864079 PMID:19217321 RGD:10053643 RGD:10054095 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO protein:increased expression:chondrocyte RGD PMID:16864079 PMID:19217321 RGD:10053643 RGD:10054095 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Becn1 beclin 1 ISO protein:decreased expression:cartilage RGD PMID:20187128 RGD:6483317 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Bglap bone gamma-carboxyglutamate protein disease_progression ISO RGD PMID:20157712 RGD:6483599 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978
JBrowse link
G Bmp2 bone morphogenetic protein 2 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Cav1 caveolin 1 ISO RGD PMID:16508959 RGD:10043354 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:synovial membrane: RGD PMID:19942450 RGD:10054497 NCBI chrNW_004955421:205,297...210,944
Ensembl chrNW_004955421:205,297...210,944
JBrowse link
G Cd36 CD36 molecule susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Cebpb CCAAT enhancer binding protein beta susceptibility ISO RGD PMID:22095691 RGD:10401214 NCBI chrNW_004955445:8,060,432...8,061,289 JBrowse link
G Chi3l1 chitinase 3 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955406:39,195,101...39,201,808
Ensembl chrNW_004955406:39,191,073...39,202,020
JBrowse link
G Cilp cartilage intermediate layer protein disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955450:10,231,082...10,244,632
Ensembl chrNW_004955450:10,232,641...10,245,945
JBrowse link
G Clec3b C-type lectin domain family 3 member B disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955420:26,665,472...26,669,474 JBrowse link
G Clic1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955437:269,276...275,949
Ensembl chrNW_004955437:269,276...275,949
JBrowse link
G Clic4 chloride intracellular channel 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955452:4,479,783...4,534,115
Ensembl chrNW_004955452:4,479,783...4,534,115
JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 PMID:18784066 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
JBrowse link
G Col1a1 collagen type I alpha 1 chain no_association ISO DNA:SNP:intron:IVS1 RGD PMID:10743824 RGD:5688331 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955432:11,127,961...11,164,145
Ensembl chrNW_004955432:11,128,112...11,163,302
JBrowse link
G Col2a1 collagen type II alpha 1 chain onset
treatment
ISO DNA:missense mutation:exon:p.R75C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9061443 PMID:16189708 PMID:16755660 PMID:19216861 RGD:8657384 RGD:8661226 NCBI chrNW_004955500:6,860,771...6,885,466
Ensembl chrNW_004955500:6,860,771...6,885,473
JBrowse link
G Col6a2 collagen type VI alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955407:42,575,677...42,600,967
Ensembl chrNW_004955407:42,575,170...42,600,495
JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955422:13,576,315...13,584,267 JBrowse link
G Ctsk cathepsin K ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955588:149,036...158,093
Ensembl chrNW_004955588:148,748...158,093
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955496:7,813,540...7,855,754
Ensembl chrNW_004955496:7,813,540...7,855,539
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 disease_progression ISO RGD PMID:24938620 RGD:150429973 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968
JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220
JBrowse link
G Dpep1 dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955541:3,204,421...3,215,514
Ensembl chrNW_004955541:3,204,055...3,215,565
JBrowse link
G Dpysl2 dihydropyrimidinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955403:49,188,259...49,306,916
Ensembl chrNW_004955403:49,188,205...49,307,810
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955418:26,391,309...26,680,553
Ensembl chrNW_004955418:26,391,299...26,680,553
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955495:4,800,103...4,807,714
Ensembl chrNW_004955495:4,799,922...4,807,252
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 ISO mRNA:increased expression:articular cartilage of joint (rat) RGD PMID:31396630 RGD:42722015 NCBI chrNW_004955422:19,463,090...19,470,605
Ensembl chrNW_004955422:19,463,987...19,470,605
JBrowse link
G Egr1 early growth response 1 ISO mRNA, protein: decreased expression RGD PMID:10806043 RGD:1626498 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809
JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO mRNA:increased expression:cartilage
protein:increased expression:layer of synovial tissue, stromal cell
RGD PMID:12823854 PMID:20495569 PMID:21869830 RGD:10395364 RGD:10395365 RGD:10395366 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO mRNA:decreased expression:knee, articular cartilage of joint RGD PMID:24964749 RGD:10045611 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582
JBrowse link
G Esd esterase D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955431:524,491...551,871
Ensembl chrNW_004955431:525,795...547,922
JBrowse link
G Esr1 estrogen receptor 1 ISO DNA:SNPs:introns: (rs2234693, rs9340799) (human)
DNA:SNP:intron: (rs2234693) (human)
RGD PMID:19884274 PMID:20417295 RGD:10045662 RGD:10045830 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G Esr2 estrogen receptor 2 ISO DNA:SNP:intron: (rs1256031) (human) RGD PMID:19884274 RGD:10045830 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955450:1,392,526...1,451,591
Ensembl chrNW_004955450:1,392,479...1,451,591
JBrowse link
G Ezr ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955439:3,701,722...3,740,345
Ensembl chrNW_004955439:3,703,013...3,740,345
JBrowse link
G Fgf18 fibroblast growth factor 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955408:24,225,459...24,260,057
Ensembl chrNW_004955408:24,225,459...24,260,092
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO RGD PMID:22393163 RGD:10402075 NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO mRNA:increased expression:trabecular bone: RGD PMID:15781004 RGD:10402109 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:cartilage: RGD PMID:8646429 RGD:10402156 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Frzb frizzled related protein susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Osteoarthritis
ClinVar Annotator: match by term: Osteoarthritis susceptibility 1
OMIM
CTD
ClinVar
PMID:15210948 PMID:25741868 NCBI chrNW_004955403:14,598,765...14,627,997
Ensembl chrNW_004955403:14,598,765...14,631,154
JBrowse link
G Ftl ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955559:1,691,722...1,693,381 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783
JBrowse link
G Gdf5 growth differentiation factor 5 ISO OMIM NCBI chrNW_004955422:25,992,081...25,997,122
Ensembl chrNW_004955422:25,992,081...25,997,122
JBrowse link
G Ghr growth hormone receptor ISO DNA:deletion:exon: RGD PMID:23740230 RGD:10003113 NCBI chrNW_004955426:26,553,509...26,873,619
Ensembl chrNW_004955426:26,689,581...26,871,684
JBrowse link
G Gls glutaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955403:8,195,241...8,261,402
Ensembl chrNW_004955403:8,195,255...8,261,402
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955494:383,107...387,483
Ensembl chrNW_004955494:383,341...387,630
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955469:8,183,945...8,233,869
Ensembl chrNW_004955469:8,183,945...8,233,869
JBrowse link
G Hbp1 HMG-box transcription factor 1 ISO RGD PMID:22586168 RGD:10402054 NCBI chrNW_004955410:11,626,743...11,652,343
Ensembl chrNW_004955410:11,626,743...11,652,343
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955403:8,752,339...8,796,693
Ensembl chrNW_004955403:8,752,309...8,792,927
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 PMID:18789153 RGD:10395366 RGD:10402406 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hmgb1 high mobility group box 1 ISO RGD PMID:22330250 RGD:10401949 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955416:15,197,611...15,212,919
Ensembl chrNW_004955416:15,197,366...15,223,363
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955450:685,905...703,593
Ensembl chrNW_004955450:685,905...703,586
JBrowse link
G Igf1 insulin like growth factor 1 ISO protein:decreased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Igf1r insulin like growth factor 1 receptor severity ISO mRNA:increased expression:articular cartilage of joint: RGD PMID:8609369 RGD:10045889 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Igf2 insulin like growth factor 2 ISO mRNA:increased expression:cartilage RGD PMID:22527881 RGD:10402552 NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO RGD PMID:18775662 RGD:10402575 NCBI chrNW_004955456:6,795,560...6,802,147
Ensembl chrNW_004955456:6,795,604...6,800,845
JBrowse link
G Ihh Indian hedgehog signaling molecule ISO protein:increased expression:cartilage RGD PMID:24786088 RGD:12910979 NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747
JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:chonodrocyte: RGD PMID:9497936 RGD:10047053 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Il1b interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:21954917 PMID:22890185 RGD:7207218 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il4r interleukin 4 receptor ISO protein:increased expression:serum RGD PMID:16647277 RGD:10402785 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Il5 interleukin 5 ISO RGD PMID:22035391 RGD:5687147 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
JBrowse link
G Immt inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955424:1,438,158...1,476,552
Ensembl chrNW_004955424:1,438,158...1,476,552
JBrowse link
G Ins insulin ISO protein:increased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Isoc2 isochorismatase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955567:829,799...835,322
Ensembl chrNW_004955567:829,300...835,505
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO RGD PMID:18354251 RGD:6482239 NCBI chrNW_004955415:20,490,414...20,526,068
Ensembl chrNW_004955415:20,490,414...20,527,917
JBrowse link
G Lep leptin severity ISO protein:increased expression:tibia, cartilage, chondrocyte (human) RGD PMID:14613274 RGD:10053634 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like ISO RGD PMID:20434574 RGD:2324964 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11790802 PMID:12379497 NCBI chrNW_004955422:19,714,161...19,730,344
Ensembl chrNW_004955422:19,714,627...19,729,855
JBrowse link
G Matn3 matrilin 3 susceptibility ISO ClinVar Annotator: match by term: Osteoarthritis susceptibility 2
ClinVar Annotator: match by term: OSTEOARTHRITIS OF DISTAL INTERPHALANGEAL JOINTS
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12736871 PMID:14729835 PMID:25741868 PMID:28492532 NCBI chrNW_004955469:2,548,443...2,568,497
Ensembl chrNW_004955469:2,548,443...2,568,497
JBrowse link
G Mmp13 matrix metallopeptidase 13 treatment ISO mRNA, protein:increased expression:cartilage RGD PMID:11134178 PMID:16128596 PMID:17530714 PMID:22890185 PMID:23982761 RGD:10043101 RGD:10043117 RGD:2300093 RGD:7207089 RGD:7207218 NCBI chrNW_004955412:6,106,994...6,118,760
Ensembl chrNW_004955412:6,106,994...6,118,760
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO protein:increased expression:synovial fluid (human) RGD PMID:15194590 RGD:7207131 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
JBrowse link
G Mmp8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chrNW_004955412:5,928,997...5,939,012
Ensembl chrNW_004955412:5,928,997...5,939,012
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Msn moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955475:5,301,856...5,370,378
Ensembl chrNW_004955475:5,301,910...5,370,691
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:22084394 PMID:24651621 RGD:10003163 RGD:10003165 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
G Mvp major vault protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955493:7,113,194...7,141,944
Ensembl chrNW_004955493:7,113,319...7,143,582
JBrowse link
G Myh13 myosin heavy chain 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955467:6,816,393...6,872,754
Ensembl chrNW_004955467:6,816,393...6,872,754
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D ISO protein:increased expression:spinal cord RGD PMID:20722027 RGD:10412653 NCBI chrNW_004955410:8,217,684...8,233,302
Ensembl chrNW_004955410:8,220,400...8,247,486
JBrowse link
G Ncor2 nuclear receptor corepressor 2 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955482:4,927,482...5,031,848
Ensembl chrNW_004955482:4,942,221...5,031,904
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955422:17,781,374...17,785,395
Ensembl chrNW_004955422:17,781,204...17,784,404
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955422:17,876,496...17,881,773
Ensembl chrNW_004955422:17,873,872...17,881,773
JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955420:14,927,490...15,007,082
Ensembl chrNW_004955420:14,923,575...15,007,081
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955413:4,429,558...4,440,602
Ensembl chrNW_004955413:4,429,633...4,440,256
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955421:1,034,843...1,109,637
Ensembl chrNW_004955421:1,034,843...1,110,438
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 alpha 1 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955586:98,492...114,927
Ensembl chrNW_004955586:97,172...114,928
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO mRNA:increased expression:tibia (rat) RGD PMID:21864409 RGD:6771362 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
JBrowse link
G Plcd1 phospholipase C delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955421:4,856,366...4,880,309
Ensembl chrNW_004955421:4,856,366...4,880,309
JBrowse link
G Plod2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955474:11,392,163...11,473,918
Ensembl chrNW_004955474:11,392,163...11,475,508
JBrowse link
G Pls3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955490:125,913...221,152
Ensembl chrNW_004955490:122,328...221,388
JBrowse link
G Pomc proopiomelanocortin ISO RGD PMID:21378032 RGD:5508809 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit Aalpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955558:381,794...410,485 JBrowse link
G Psmb1 proteasome 20S subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955411:3,285,610...3,304,210
Ensembl chrNW_004955411:3,286,835...3,304,931
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO DNA:SNP (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15334463 PMID:32004530 RGD:1625347 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ran RAN, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955482:1,222,944...1,223,891 JBrowse link
G Rcn3 reticulocalbin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955559:1,309,621...1,319,925
Ensembl chrNW_004955559:1,309,621...1,319,925
JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955437:10,598,145...10,885,858
Ensembl chrNW_004955437:10,598,145...10,800,560
JBrowse link
G S100a4 S100 calcium binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16948116 NCBI chrNW_004955545:192,236...194,468
Ensembl chrNW_004955545:192,116...195,394
JBrowse link
G Scrn1 secernin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955410:31,231,418...31,299,772
Ensembl chrNW_004955410:31,231,119...31,298,152
JBrowse link
G Sdcbp syndecan binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955454:17,093,930...17,113,491
Ensembl chrNW_004955454:17,089,232...17,113,484
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955504:36,939...66,507 JBrowse link
G Sec23a SEC23 homolog A, COPII coat complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955409:22,192,549...22,243,090
Ensembl chrNW_004955409:22,189,181...22,247,467
JBrowse link
G Sgcg sarcoglycan gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955497:3,592,041...3,702,780
Ensembl chrNW_004955497:3,615,003...3,701,300
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18973239 NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21217753 PMID:22772368 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 PMID:18784066 PMID:22108257 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A susceptibility ISO DNA:repeats: : RGD PMID:25231575 RGD:14390133 NCBI chrNW_004955411:9,695,149...9,701,463
Ensembl chrNW_004955411:9,699,011...9,701,507
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chrNW_004955432:10,635,626...10,641,345
Ensembl chrNW_004955432:10,631,843...10,641,538
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955445:18,544,192...18,576,576
Ensembl chrNW_004955445:18,544,183...18,576,570
JBrowse link
G Tlr8 toll like receptor 8 ISO ClinVar Annotator: match by term: Osteoarthritis ClinVar NCBI chrNW_004955544:302,027...317,110
Ensembl chrNW_004955544:303,319...306,426
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO RGD PMID:14872496 RGD:2290500 NCBI chrNW_004955420:2,550,392...2,566,448
Ensembl chrNW_004955420:2,549,142...2,566,564
JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955419:12,863,617...12,884,498
Ensembl chrNW_004955419:12,863,615...12,879,517
JBrowse link
G Trap1 TNF receptor associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955442:13,697,471...13,733,161
Ensembl chrNW_004955442:13,696,810...13,733,161
JBrowse link
G Trim2 tripartite motif containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955471:7,523,895...7,698,436
Ensembl chrNW_004955471:7,594,966...7,698,436
JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21964574 NCBI chrNW_004955455:8,744,865...8,781,644
Ensembl chrNW_004955455:8,744,176...8,783,741
JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955405:38,863,762...38,928,615
Ensembl chrNW_004955405:38,903,918...38,927,410
JBrowse link
G Vdac2 voltage dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955437:16,857,715...16,871,717
Ensembl chrNW_004955437:16,853,433...16,872,345
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16876394 PMID:18784066 NCBI chrNW_004955429:10,708,852...10,716,743
Ensembl chrNW_004955429:10,707,719...10,717,554
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chrNW_004955487:5,229,485...5,263,749
Ensembl chrNW_004955487:5,230,506...5,263,752
JBrowse link
Osteoarthritis with Mild Chondrodysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain ISO OMIM NCBI chrNW_004955500:6,860,771...6,885,466
Ensembl chrNW_004955500:6,860,771...6,885,473
JBrowse link
Osteoarthritis, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO RGD PMID:19404941 RGD:9068434 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp6 caspase 6 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chrNW_004955496:575,839...584,287
Ensembl chrNW_004955496:577,832...584,287
JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524
JBrowse link
G Casp8 caspase 8 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment ISO RGD PMID:25128628 RGD:11041187 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 treatment ISO RGD PMID:25975052 RGD:150429975 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO RGD PMID:22833219 RGD:10402072 NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23041435 RGD:10402106 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO mRNA:decreased expression:knee RGD PMID:24754147 RGD:10412054 NCBI chrNW_004955514:2,195,228...2,208,258
Ensembl chrNW_004955514:2,195,228...2,208,688
JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO RGD PMID:29364174 RGD:13800565 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO protein:decreased expression:skeletal joint RGD PMID:31742919 RGD:40924673 NCBI chrNW_004955412:14,630,109...14,923,847
Ensembl chrNW_004955412:14,630,443...14,923,926
JBrowse link
G Serpinf1 serpin family F member 1 severity ISO RGD PMID:28122611 RGD:27226703 NCBI chrNW_004955481:1,414,930...1,426,436
Ensembl chrNW_004955481:1,414,930...1,426,241
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chrNW_004955482:760,200...777,133
Ensembl chrNW_004955482:761,811...777,133
JBrowse link
Osteoarthritis, Hip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO mRNA:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chrNW_004955407:26,597,165...26,643,972
Ensembl chrNW_004955407:26,603,479...26,643,103
JBrowse link
G Aspn asporin ISO DNA:repeats:exon: RGD PMID:15640800 RGD:9684965 NCBI chrNW_004955515:5,322,074...5,345,715
Ensembl chrNW_004955515:5,321,943...5,345,894
JBrowse link
G Astn2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955419:10,486,200...11,387,553
Ensembl chrNW_004955419:10,486,118...11,390,085
JBrowse link
G Chadl chondroadherin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28319091 PMID:30374069 NCBI chrNW_004955413:26,846,714...26,862,082
Ensembl chrNW_004955413:26,851,420...26,862,081
JBrowse link
G Col10a1 collagen type X alpha 1 chain ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chrNW_004955526:641,577...679,295 JBrowse link
G Col11a1 collagen type XI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955435:7,352,617...7,545,235
Ensembl chrNW_004955435:7,352,617...7,545,235
JBrowse link
G Col1a1 collagen type I alpha 1 chain susceptibility
no_association
ISO DNA:SNP:intron:g.2046G>T (human) RGD PMID:9811048 PMID:15880349 PMID:17187661 RGD:5688305 RGD:5688306 RGD:5688330 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825
JBrowse link
G Diablo diablo IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955482:6,354,502...6,364,424
Ensembl chrNW_004955482:6,354,146...6,365,344
JBrowse link
G Esr1 estrogen receptor 1 ISO DNA:SNP:intron:g.-397T>C (human) RGD PMID:17419075 RGD:10045661 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G Filip1 filamin A interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955502:3,806,016...3,976,013
Ensembl chrNW_004955502:3,823,872...3,903,481
JBrowse link
G Gdf5 growth differentiation factor 5 ISO ClinVar Annotator: match by term: Osteoarthritis of hip ClinVar PMID:17384641 PMID:28492532 NCBI chrNW_004955422:25,992,081...25,997,122
Ensembl chrNW_004955422:25,992,081...25,997,122
JBrowse link
G Ghr growth hormone receptor ISO associated with Acromegaly;DNA:deletion:exon: RGD PMID:19864451 RGD:10003142 NCBI chrNW_004955426:26,553,509...26,873,619
Ensembl chrNW_004955426:26,689,581...26,871,684
JBrowse link
G Hdac9 histone deacetylase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955410:21,046,312...21,932,029
Ensembl chrNW_004955410:21,245,562...21,932,023
JBrowse link
G Hfe homeostatic iron regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 PMID:30664745 NCBI chrNW_004955567:868,272...883,563
Ensembl chrNW_004955567:871,489...883,563
JBrowse link
G Il4r interleukin 4 receptor no_association
susceptibility
ISO DNA:missense mutations:cds:p.S411L, p.S727A (rs1805013, rs1805016) (human)
DNA:SNPs:multiple
RGD PMID:14745651 PMID:19036616 RGD:10402782 RGD:10402784 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Itih1 inter-alpha-trypsin inhibitor heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955430:2,738,128...2,751,007
Ensembl chrNW_004955430:2,737,859...2,751,379
JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955419:1,782,566...1,857,375
Ensembl chrNW_004955419:1,782,566...1,857,375
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955422:19,714,161...19,730,344
Ensembl chrNW_004955422:19,714,627...19,729,855
JBrowse link
G Mapt microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chrNW_004955412:6,106,994...6,118,760
Ensembl chrNW_004955412:6,106,994...6,118,760
JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955437:10,598,145...10,885,858
Ensembl chrNW_004955437:10,598,145...10,800,560
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
JBrowse link
G Smo smoothened, frizzled class receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955479:9,963,377...9,991,670
Ensembl chrNW_004955479:9,964,170...9,993,165
JBrowse link
G Tnc tenascin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chrNW_004955419:12,569,620...12,662,897
Ensembl chrNW_004955419:12,569,547...12,662,958
JBrowse link
otulipenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otulin OTU deubiquitinase with linear linkage specificity ISO OMIM NCBI chrNW_004955426:3,953,852...3,982,532
Ensembl chrNW_004955426:3,953,933...3,982,175
JBrowse link
polymyalgia rheumatica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone no_association ISO DNA:polymorphism:promoter RGD PMID:12051390 RGD:1581301 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30657865 RGD:14746966 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Mbl2 mannose binding lectin 2 ISO DNA:polymorphism:cds: RGD PMID:12375325 RGD:8693752 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:plasma, endothelial microparticle (human) RGD PMID:22211720 RGD:6771319 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
JBrowse link
Reynolds Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lbr lamin B receptor ISO OMIM NCBI chrNW_004955520:401,733...418,279 JBrowse link
rheumatic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gc GC vitamin D binding protein ISO RGD PMID:2737695 RGD:5509933 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:14567831 RGD:13702910 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
rheumatic heart disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule ISO mRNA:decreased expression:blood, mononuclear cell RGD PMID:16741676 RGD:6893529 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Fcn3 ficolin 3 ISO ClinVar Annotator: match by term: Rheumatic heart disease ClinVar NCBI chrNW_004955452:6,630,548...6,635,334
Ensembl chrNW_004955452:6,630,505...6,635,235
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO RGD PMID:26823728 RGD:13792679 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783
JBrowse link
G Igf1 insulin like growth factor 1 ISO RGD PMID:16406300 RGD:1582623 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il10 interleukin 10 no_association ISO RGD PMID:16043936 RGD:1598626 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
rheumatic myocarditis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Sele selectin E severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chrNW_004955462:7,564,437...7,575,297 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691
JBrowse link
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20080907 PMID:22104130 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955507:5,724,788...5,791,281
Ensembl chrNW_004955507:5,724,762...5,790,812
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955451:11,087,246...11,130,108
Ensembl chrNW_004955451:11,087,570...11,130,482
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955404:14,700,808...14,927,944
Ensembl chrNW_004955404:14,700,808...14,928,617
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955420:23,447,920...23,522,732
Ensembl chrNW_004955420:23,447,920...23,522,732
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
G Acan aggrecan disease_progression ISO protein:increased degradation:cartilage
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15292528 PMID:16507130 RGD:11570537 NCBI chrNW_004955416:16,125,536...16,186,046 JBrowse link
G Ackr3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955453:195,346...218,034
Ensembl chrNW_004955453:195,346...218,034
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ISO mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chrNW_004955468:12,950,333...12,958,599
Ensembl chrNW_004955468:12,951,155...12,958,212
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chrNW_004955407:26,597,165...26,643,972
Ensembl chrNW_004955407:26,603,479...26,643,103
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12833524 PMID:21789720 RGD:5686424 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chrNW_004955463:13,663,064...13,665,553 JBrowse link
G Aff3 AF4/FMR2 family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955470:5,800,152...6,183,761
Ensembl chrNW_004955470:5,804,117...6,183,222
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16385501 PMID:20541603 RGD:7244141 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chrNW_004955410:20,428,531...20,459,482 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909
JBrowse link
G Ankrd55 ankyrin repeat domain 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955446:11,622,317...11,713,690
Ensembl chrNW_004955446:11,622,124...11,714,069
JBrowse link
G Anxa3 annexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955433:2,981,113...3,043,894
Ensembl chrNW_004955433:2,977,513...3,044,446
JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Arid5b AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 PMID:23143596 NCBI chrNW_004955425:15,253,951...15,433,246
Ensembl chrNW_004955425:15,253,211...15,433,934
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chrNW_004955457:704,213...729,702
Ensembl chrNW_004955457:704,213...730,134
JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955424:21,859,901...21,888,722
Ensembl chrNW_004955424:21,859,901...21,888,722
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955484:9,462,517...9,467,314 JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955460:14,174,592...14,259,416
Ensembl chrNW_004955460:14,176,111...14,258,971
JBrowse link
G Bcl2a1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955533:773,912...785,040
Ensembl chrNW_004955533:773,912...785,037
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO protein:increased expression:serum RGD PMID:3488088 PMID:22447331 RGD:6483593 RGD:6483600 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978
JBrowse link
G Bgn biglycan ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chrNW_004955580:252,183...263,179
Ensembl chrNW_004955580:252,139...263,663
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955403:52,825,397...52,874,007
Ensembl chrNW_004955403:52,832,604...52,874,264
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Btnl2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chrNW_004955437:1,084,330...1,101,751
Ensembl chrNW_004955437:1,083,745...1,101,730
JBrowse link
G C3 complement C3 ISO RGD PMID:7561187 RGD:11040775 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G Cald1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chrNW_004955494:7,578,162...7,675,558 JBrowse link
G Casp7 caspase 7 ISO RGD PMID:18785314 RGD:5684540 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524
JBrowse link
G Cast calpastatin ISO RGD PMID:7706496 RGD:5683620 NCBI chrNW_004955418:15,859,951...15,974,141
Ensembl chrNW_004955418:15,862,729...15,916,169
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Cav2 caveolin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955432:22,240,041...22,242,200 JBrowse link
G Ccl21 C-C motif chemokine ligand 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chrNW_004955472:1,427,660...1,428,771
Ensembl chrNW_004955472:1,427,710...1,429,102
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032
JBrowse link
G Ccn1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166
JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:synovium:
protein:increased expression:synovial membrane:
RGD PMID:19942450 PMID:25430645 RGD:10054497 RGD:10054499 NCBI chrNW_004955421:205,297...210,944
Ensembl chrNW_004955421:205,297...210,944
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453841 PMID:20453842 PMID:23143596 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191
JBrowse link
G Cd2 CD2 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955435:19,861,658...19,876,383
Ensembl chrNW_004955435:19,861,527...19,873,581
JBrowse link
G Cd244 CD244 molecule susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:18794858 NCBI chrNW_004955468:12,532,937...12,559,859
Ensembl chrNW_004955468:12,534,064...12,559,434
JBrowse link
G Cd28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19075187 PMID:19898481 PMID:20453842 PMID:23143596 RGD:5131619 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991
JBrowse link
G Cd3e CD3e molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990
JBrowse link
G Cd40 CD40 molecule ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs4810485 (human)
CTD
RGD
PMID:18794853 PMID:20453842 PMID:20498205 PMID:23143596 RGD:5490972 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Cd5 CD5 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955511:5,656,333...5,670,510
Ensembl chrNW_004955511:5,664,682...5,669,368
JBrowse link
G Cd80 CD80 molecule ISO protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chrNW_004955427:19,237,251...19,274,001
Ensembl chrNW_004955427:19,236,445...19,261,517
JBrowse link
G Cd83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955465:676,006...692,770
Ensembl chrNW_004955465:674,168...693,353
JBrowse link
G Cdk6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chrNW_004955432:9,521,794...9,727,772
Ensembl chrNW_004955432:9,521,794...9,726,417
JBrowse link
G Cebpb CCAAT enhancer binding protein beta ISO protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chrNW_004955445:8,060,432...8,061,289 JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chrNW_004955406:39,195,101...39,201,808
Ensembl chrNW_004955406:39,191,073...39,202,020
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chrNW_004955453:3,425,603...3,432,695
Ensembl chrNW_004955453:3,425,603...3,432,695
JBrowse link
G Ciita class II major histocompatibility complex transactivator susceptibility
no_association
ISO ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:haplotype:promoter/CDS:rs3087456G/rs4774C
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
RGD
CTD
PMID:15821736 PMID:16426246 PMID:16849401 PMID:19221398 PMID:25741868 More... RGD:5491176 RGD:5491189 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624
JBrowse link
G Clec16a C-type lectin domain containing 16A ISO DNA:polymorphism:intron:rs6498169G RGD PMID:19221398 RGD:5491176 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:27028940 PMID:29935983 NCBI chrNW_004955500:6,860,771...6,885,466
Ensembl chrNW_004955500:6,860,771...6,885,473
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chrNW_004955448:470,063...522,909
Ensembl chrNW_004955448:473,179...523,100
JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460
JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955422:13,576,315...13,584,267 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chrNW_004955433:15,023,272...15,034,650
Ensembl chrNW_004955433:15,023,050...15,034,711
JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:19192274 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chrNW_004955475:11,148,928...11,152,313
Ensembl chrNW_004955475:11,148,879...11,152,596
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
JBrowse link
G Ddit4 DNA damage inducible transcript 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955437:19,322,407...19,324,562
Ensembl chrNW_004955437:19,322,407...19,324,562
JBrowse link
G Ddx6 DEAD-box helicase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955412:19,854,785...19,889,422
Ensembl chrNW_004955412:19,854,785...19,889,426
JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955418:29,274,170...29,283,028 JBrowse link
G Dnase1l3 deoxyribonuclease 1 like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chrNW_004955430:7,867,172...7,892,079
Ensembl chrNW_004955430:7,867,109...7,892,079
JBrowse link
G Dnmt1 DNA methyltransferase 1 severity ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chrNW_004955422:28,380,595...28,427,012
Ensembl chrNW_004955422:28,380,591...28,421,301
JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:22249931 RGD:8661695 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
JBrowse link
G Eln elastin ISO RGD PMID:12643515 RGD:9585739 NCBI chrNW_004955456:13,788,992...13,818,836 JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809
JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369
JBrowse link
G Esr2 estrogen receptor 2 severity ISO DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO protein:increased expression:serum (human)
DNA:snp:promoter:g.-670A>G (human)
RGD PMID:12148596 PMID:20875116 PMID:23053964 RGD:12903969 RGD:8662433 RGD:8662455 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955437:3,445,515...3,548,874
Ensembl chrNW_004955437:3,447,075...3,548,564
JBrowse link
G Foxo3 forkhead box O3 ISO mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chrNW_004955411:33,655,958...33,770,829
Ensembl chrNW_004955411:33,655,958...33,770,829
JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
JBrowse link
G Fpgs folylpolyglutamate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955419:853,891...871,729
Ensembl chrNW_004955419:851,152...871,522
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955407:32,944,638...32,975,142
Ensembl chrNW_004955407:32,944,164...32,973,863
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744
JBrowse link
G Gc GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma
CTD
RGD
PMID:3874814 PMID:9548303 RGD:5509931 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491
JBrowse link
G Gdf5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chrNW_004955422:25,992,081...25,997,122
Ensembl chrNW_004955422:25,992,081...25,997,122
JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chrNW_004955444:15,901,225...15,930,358
Ensembl chrNW_004955444:15,900,485...15,931,338
JBrowse link
G Gin1 gypsy retrotransposon integrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955418:10,898,069...10,918,460
Ensembl chrNW_004955418:10,898,293...10,918,544
JBrowse link
G Gprc5a G protein-coupled receptor class C group 5 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955413:9,765,564...9,784,847
Ensembl chrNW_004955413:9,765,564...9,785,856
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein: decreased expression: mononuclear leukocytes
CTD Direct Evidence: marker/mechanism
DNA: deletion: : heterozygous
RGD
CTD
PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 no_association ISO DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis
protein: : mononuclear blood cells
RGD PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chrNW_004955551:43,918...255,118
Ensembl chrNW_004955551:44,156...254,534
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear leukocytes
DNA: deletion: : homozygous
CTD
RGD
PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chrNW_004955408:29,665,534...29,684,225
Ensembl chrNW_004955408:29,665,260...29,684,207
JBrowse link
G Gsdme gasdermin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955410:26,700,977...26,761,683
Ensembl chrNW_004955410:26,701,893...26,769,989
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955418:26,848,302...26,912,151
Ensembl chrNW_004955418:26,848,303...26,913,339
JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955427:20,999,934...21,020,401
Ensembl chrNW_004955427:20,999,485...21,020,531
JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chrNW_004955452:10,636,366...10,668,873
Ensembl chrNW_004955452:10,636,366...10,670,864
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hgf hepatocyte growth factor disease_progression ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chrNW_004955410:28,032,193...28,042,459
Ensembl chrNW_004955410:28,032,193...28,042,459
JBrowse link
G Hoxd10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955403:20,543,224...20,548,801
Ensembl chrNW_004955403:20,543,224...20,548,801
JBrowse link
G Hoxd11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955403:20,541,870...20,556,574 JBrowse link
G Hoxd13 homeobox D13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955403:20,568,314...20,575,579
Ensembl chrNW_004955403:20,568,314...20,575,579
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955489:2,500,928...2,524,715
Ensembl chrNW_004955489:2,497,680...2,524,805
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chrNW_004955538:1,469,544...1,475,010 JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chrNW_004955408:4,379,825...4,422,710
Ensembl chrNW_004955408:4,379,825...4,423,381
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chrNW_004955418:1,915,985...1,931,017
Ensembl chrNW_004955418:1,915,985...1,931,017
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chrNW_004955844:8,094...9,565
Ensembl chrNW_004955844:7,790...10,004
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chrNW_004955403:3,062,724...3,073,419
Ensembl chrNW_004955403:3,063,133...3,073,419
JBrowse link
G Ifng interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:1417133 PMID:22450443 RGD:8157623 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf2 insulin like growth factor 2 ISO DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma
RGD PMID:11247331 PMID:19556211 RGD:5510001 RGD:5510014 NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955456:6,795,560...6,802,147
Ensembl chrNW_004955456:6,795,604...6,800,845
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955451:14,483,669...14,571,108
Ensembl chrNW_004955451:14,484,132...14,536,916
JBrowse link
G Il10 interleukin 10 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis, progression of
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12847677 PMID:22450443 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il17a interleukin 17A treatment ISO RGD PMID:20926833 RGD:9068415 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
JBrowse link
G Il19 interleukin 19 ISO ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar PMID:12847677 NCBI chrNW_004955406:42,376,102...42,384,902
Ensembl chrNW_004955406:42,376,104...42,384,902
JBrowse link
G Il1a interleukin 1 alpha severity ISO associated with lung disease, interstitial
protein:increased expression:plasma, synovial fluid
RGD PMID:8162643 PMID:11192540 RGD:4142818 RGD:7794716 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:serum
CTD
RGD
PMID:12566094 PMID:17379860 PMID:22414257 PMID:22450443 RGD:6482656 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:7706905 PMID:10637275 PMID:19192274 PMID:19447938 RGD:7174696 RGD:8549810 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:6421522 RGD:8662948 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il20 interleukin 20 ISO RGD PMID:16947773 RGD:5147395 NCBI chrNW_004955406:42,398,510...42,401,561
Ensembl chrNW_004955406:42,398,782...42,401,490
JBrowse link
G Il21r interleukin 21 receptor ISO RGD PMID:19342640 RGD:6892964 NCBI chrNW_004955493:5,613,704...5,646,692
Ensembl chrNW_004955493:5,613,564...5,650,583
JBrowse link
G Il23a interleukin 23 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:20476861 PMID:23143596 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955413:23,623,567...23,640,245
Ensembl chrNW_004955413:23,623,154...23,640,259
JBrowse link
G Il4r interleukin 4 receptor severity ISO DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Il5 interleukin 5 ISO RGD PMID:22293286 RGD:5687156 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 PMID:22450443 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16729287 PMID:23143596 NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chrNW_004955446:11,790,636...11,837,734
Ensembl chrNW_004955446:11,790,444...11,835,001
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622
JBrowse link
G Irf8 interferon regulatory factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955541:973,004...988,493
Ensembl chrNW_004955541:973,022...990,106
JBrowse link
G Itga6 integrin subunit alpha 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955449:2,590,982...2,665,887
Ensembl chrNW_004955449:2,590,982...2,665,887
JBrowse link
G Itpa inosine triphosphatase treatment ISO DNA:SNP: :94C>A(human) RGD PMID:29441893 RGD:14975307 NCBI chrNW_004955415:14,106,786...14,121,975
Ensembl chrNW_004955415:14,107,380...14,121,619
JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:21510883 RGD:6483024 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kif5a kinesin family member 5A susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:snps:intron, 3' utr:c.2756-43A>C, c.*776C>T (rs775246, rs775251) (human)
DNA:snp:intron:c.1717-152C>G (rs1678542) (human)
CTD
RGD
PMID:21784728 PMID:23143596 PMID:23378462 RGD:12793072 RGD:12793073 NCBI chrNW_004955458:5,264,274...5,310,962
Ensembl chrNW_004955458:5,287,111...5,310,962
JBrowse link
G Lhx2 LIM homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955419:3,999,364...4,019,543
Ensembl chrNW_004955419:3,998,242...4,018,875
JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:17956852 PMID:22286218 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO RGD PMID:17082220 RGD:5508419 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Ly96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chrNW_004955444:6,356,121...6,387,350
Ensembl chrNW_004955444:6,356,154...6,387,529
JBrowse link
G Mab21l2 mab-21 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955471:5,296,292...5,298,432
Ensembl chrNW_004955471:5,297,259...5,298,338
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chrNW_004955402:38,761,668...38,829,830
Ensembl chrNW_004955402:38,767,419...38,830,204
JBrowse link
G Mbd4 methyl-CpG binding domain 4, DNA glycosylase no_association
susceptibility
ISO DNA:snps:cds, intron:p.E346K, IVS6-218C>T (rs140693, rs2005618) (human)
DNA:snps:introns:IVS5-140A>G (rs3138355), IVS6-218C>T (rs2005618) (human)
RGD PMID:20676650 PMID:22505706 RGD:9588977 RGD:9588978 NCBI chrNW_004955429:17,858,656...17,868,111
Ensembl chrNW_004955429:17,858,937...17,869,262
JBrowse link
G Mdk midkine ISO RGD PMID:15146411 RGD:1581200 NCBI chrNW_004955422:1,655,351...1,657,026
Ensembl chrNW_004955422:1,655,358...1,657,044
JBrowse link
G Mgarp mitochondria localized glutamic acid rich protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955428:4,365,585...4,373,902 JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Mmel1 membrane metalloendopeptidase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955486:8,635,727...8,662,793
Ensembl chrNW_004955486:8,638,233...8,663,053
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955412:5,965,388...5,976,353
Ensembl chrNW_004955412:5,965,394...5,976,382
JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955412:6,045,146...6,057,112
Ensembl chrNW_004955412:6,045,100...6,057,262
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
JBrowse link
G Mmp8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chrNW_004955412:5,928,997...5,939,012
Ensembl chrNW_004955412:5,928,997...5,939,012
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 PMID:26001728 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:22104130 PMID:23685257 RGD:7387222 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 induced ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:M153T (rat)
CTD
RGD
PMID:12833524 PMID:21275845 PMID:28135245 RGD:41404729 NCBI chrNW_004955456:13,353,780...13,363,956
Ensembl chrNW_004955456:13,354,011...13,363,891
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism, SNP:cds (rs789181) (human)
CTD
RGD
PMID:12833524 PMID:17897462 RGD:41404710 NCBI chrNW_004955406:22,355,717...22,384,746
Ensembl chrNW_004955406:22,355,724...22,384,864
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 ISO DNA:polymorphism, SNP:cds (rs729749) (human) RGD PMID:17897462 RGD:41404710 NCBI chrNW_004955413:23,388,456...23,405,121
Ensembl chrNW_004955413:23,388,018...23,408,090
JBrowse link
G Ndufa4l2 NDUFA4 mitochondrial complex associated like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955458:4,962,868...4,965,838
Ensembl chrNW_004955458:4,962,868...4,965,838
JBrowse link
G Nfkbie NFKB inhibitor epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955437:9,882,460...9,888,848
Ensembl chrNW_004955437:9,882,460...9,888,952
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:c.-132T>A (rs2071592) (human)
OMIM
ClinVar
CTD
RGD
PMID:12509789 RGD:1331681 NCBI chrNW_004955437:90,623...100,918
Ensembl chrNW_004955437:90,577...100,918
JBrowse link
G Notch4 notch receptor 4 ISO mRNA : increased expression: : cd4+ cells RGD PMID:20132067 RGD:6480790 NCBI chrNW_004955437:658,076...679,338 JBrowse link
G Npsr1 neuropeptide S receptor 1 ISO RGD PMID:20179762 RGD:4891930 NCBI chrNW_004955560:1,069,651...1,243,111
Ensembl chrNW_004955560:1,069,651...1,243,111
JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO mRNA:increased expression:paw RGD PMID:18448865 RGD:4892311 NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221
JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706
JBrowse link
G Padi2 peptidyl arginine deiminase 2 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chrNW_004955527:1,709,307...1,751,332
Ensembl chrNW_004955527:1,709,444...1,752,783
JBrowse link
G Padi4 peptidyl arginine deiminase 4 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis
CTD
ClinVar
PMID:23143596 NCBI chrNW_004955527:1,536,917...1,560,508
Ensembl chrNW_004955527:1,536,423...1,561,130
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:1708827 RGD:6482653 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Pgf placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO RGD PMID:17326817 RGD:6482776 NCBI chrNW_004955437:11,534,251...11,577,942
Ensembl chrNW_004955437:11,534,173...11,555,996
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:22011479 RGD:6484117 NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324
JBrowse link
G Plb1 phospholipase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24520335 NCBI chrNW_004955469:10,370,646...10,511,263
Ensembl chrNW_004955469:10,401,178...10,511,057
JBrowse link
G Pld4 phospholipase D family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955538:3,296,581...3,303,187
Ensembl chrNW_004955538:3,295,937...3,303,802
JBrowse link
G Plek pleckstrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955424:16,494,052...16,524,790
Ensembl chrNW_004955424:16,493,960...16,524,998
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16055108 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898481 PMID:20453842 PMID:23143596 NCBI chrNW_004955411:31,434,503...31,455,995
Ensembl chrNW_004955411:31,434,503...31,456,056
JBrowse link
G Prkcq protein kinase C theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15167967 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11978490 PMID:19192274 PMID:21905970 RGD:5508313 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955461:14,337,914...14,622,779
Ensembl chrNW_004955461:14,337,914...14,556,931
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 susceptibility
no_association
ISO ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:SNP::1858C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:cds:p.R620W (rs2476601) (human)
DNA:snp:cds:p.R263Q (rs33996649) (human)
OMIM
ClinVar
RGD
CTD
PMID:15004560 PMID:15208781 PMID:15273934 PMID:15580548 PMID:15719322 More... RGD:6484535 RGD:6484595 RGD:7829746 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552
JBrowse link
G Pxk PX domain containing serine/threonine kinase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chrNW_004955430:1,714,208...1,780,674
Ensembl chrNW_004955430:1,714,208...1,765,102
JBrowse link
G Rab8a RAB8A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955524:1,403,811...1,416,005
Ensembl chrNW_004955524:1,403,811...1,416,005
JBrowse link
G Rap2a RAP2A, member of RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955404:12,897,518...12,936,964
Ensembl chrNW_004955404:12,897,240...12,936,964
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955416:5,494,030...5,561,608
Ensembl chrNW_004955416:5,494,030...5,561,614
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955443:18,783,061...19,029,441
Ensembl chrNW_004955443:18,783,061...18,910,228
JBrowse link
G Rcan1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955407:33,873,427...33,951,762
Ensembl chrNW_004955407:33,873,383...33,951,498
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19503088 PMID:20453842 PMID:23143596 NCBI chrNW_004955424:22,909,035...22,939,651
Ensembl chrNW_004955424:22,911,541...22,939,651
JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chrNW_004955418:14,305,634...14,321,804
Ensembl chrNW_004955418:14,308,392...14,326,762
JBrowse link
G Runx1 RUNX family transcription factor 1 no_association ISO DNA:SNPs: :rs2242720, rs4816502 (human)
DNA:SNP: :rs2268277 (human)
DNA:SNP:intron:24658G>C (human)
RGD PMID:16821265 PMID:18087673 PMID:18328148 PMID:20018071 RGD:6482836 RGD:6482837 RGD:6482839 RGD:6482840 NCBI chrNW_004955407:34,108,653...34,342,657
Ensembl chrNW_004955407:34,104,035...34,342,928
JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955437:10,598,145...10,885,858
Ensembl chrNW_004955437:10,598,145...10,800,560
JBrowse link
G Sema3c semaphorin 3C ISO protein:increased expression:knee, synovium (human) RGD PMID:15077297 RGD:1580084 NCBI chrNW_004955410:4,795,658...4,953,460
Ensembl chrNW_004955410:4,794,477...4,954,906
JBrowse link
G Slc11a1 solute carrier family 11 member 1 severity ISO DNA:polymorphisms, deletion: :823C>T, p.D543N (human)
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10719815 PMID:12135431 PMID:16597321 RGD:5684967 RGD:5684971 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Slc22a4 solute carrier family 22 member 4 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:14608356 NCBI chrNW_004955408:3,671,772...3,737,946
Ensembl chrNW_004955408:3,671,772...3,737,612
JBrowse link
G Slc25a12 solute carrier family 25 member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955449:3,093,603...3,182,513
Ensembl chrNW_004955449:3,093,603...3,186,737
JBrowse link
G Sms spermine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955509:2,277,501...2,328,612
Ensembl chrNW_004955509:2,276,878...2,329,620
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 PMID:15292528 PMID:24313545 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15761492 RGD:1581382 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
JBrowse link
G Spred2 sprouty related EVH1 domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955424:19,133,568...19,250,118
Ensembl chrNW_004955424:19,133,568...19,250,118
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955403:8,156,660...8,192,018
Ensembl chrNW_004955403:8,156,660...8,194,762
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO associated with T-cell large granular lymphocyte leukemia RGD PMID:22591296 RGD:6892936 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276
JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955499:5,180,451...5,347,862
Ensembl chrNW_004955499:5,180,214...5,345,221
JBrowse link
G Supt20h SPT20 homolog, SAGA complex component ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chrNW_004955431:9,013,325...9,050,844
Ensembl chrNW_004955431:9,014,726...9,050,844
JBrowse link
G Tagap T cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955439:3,479,041...3,488,403
Ensembl chrNW_004955439:3,478,708...3,488,777
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:9645419 RGD:6482275 NCBI chrNW_004955437:1,480,217...1,499,032 JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 PMID:17379860 NCBI chrNW_004955432:10,635,626...10,641,345
Ensembl chrNW_004955432:10,631,843...10,641,538
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:15700117 RGD:5685020 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chrNW_004955450:6,604,915...6,645,305
Ensembl chrNW_004955450:6,603,879...6,645,602
JBrowse link
G Tlr1 toll like receptor 1 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:32594150 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382
JBrowse link
G Tlr2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
G Tmpo thymopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chrNW_004955405:34,526,420...34,556,740
Ensembl chrNW_004955405:34,535,306...34,554,835
JBrowse link
G Tnf tumor necrosis factor treatment
no_association
ISO CTD Direct Evidence: marker/mechanism|therapeutic
DNA:SNP:promoter:-857C>T (human)
DNA:SNP:promoter:-238G>A, -308G>A (human)
CTD
RGD
PMID:2001072 PMID:8391952 PMID:12563673 PMID:12566094 PMID:22450443 More... RGD:10450537 RGD:12904065 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955538:2,159,773...2,173,312
Ensembl chrNW_004955538:2,160,483...2,171,967
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:21841782 PMID:23143596 PMID:30224649 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO CTD Direct Evidence: therapeutic CTD PMID:23333834 NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO DNA:SNP:promoter:36G>A (human) RGD PMID:25311255 RGD:12904065 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tnfsf14 TNF superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chrNW_004955495:2,829,314...2,834,826
Ensembl chrNW_004955495:2,829,402...2,835,335
JBrowse link
G Traf1 TNF receptor associated factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:23143596 NCBI chrNW_004955419:7,117,869...7,145,274
Ensembl chrNW_004955419:7,121,382...7,137,763
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100
JBrowse link
G Txndc5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chrNW_004955465:6,034,006...6,053,779
Ensembl chrNW_004955465:6,033,968...6,053,769
JBrowse link
G Txnip thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chrNW_004955568:103,801...107,791
Ensembl chrNW_004955568:103,762...107,785
JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism