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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:arthus reaction
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Accession:DOID:1556 term browser browse the term
Definition:A hypersensitivity reaction type III disease that is characterized by local vasculitis, has_symptom pain, edema, hemorrhage, or necrosis, and has_material_basis_in deposition of antigen-antibody immune complexes in vascular or serosal walls. (DO)
Synonyms:exact_synonym: arthus phenomenon;   arthus type urticaria
 primary_id: MESH:D001183
 xref: ICD10CM:T78.41;   ICD9CM:995.21;   NCI:C34400
For additional species annotation, visit the Alliance of Genome Resources.



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arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573
JBrowse link
G CFD complement factor D ISO RGD PMID:10605043 RGD:1624328 NCBI chr 2:77,509,792...77,511,988
Ensembl chr 2:77,509,795...77,511,974
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23470165 RGD:9068463 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14396
    disease of anatomical entity 14114
      immune system disease 3941
        allergic disease 553
          hypersensitivity reaction type III disease 25
            arthus reaction 3
Path 2
Term Annotations click to browse term
  disease 14396
    disease of anatomical entity 14114
      Immune & Inflammatory Diseases 4502
        immune system disease 3941
          hypersensitivity reaction disease 146
            hypersensitivity reaction type III disease 25
              arthus reaction 3
paths to the root