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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:arthus reaction
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Accession:DOID:1556 term browser browse the term
Definition:A hypersensitivity reaction type III disease that is characterized by local vasculitis, has_symptom pain, edema, hemorrhage, or necrosis, and has_material_basis_in deposition of antigen-antibody immune complexes in vascular or serosal walls. (DO)
Synonyms:exact_synonym: arthus phenomenon;   arthus type urticaria
 primary_id: MESH:D001183
 xref: ICD10CM:T78.41;   ICD9CM:995.21;   NCI:C34400
For additional species annotation, visit the Alliance of Genome Resources.


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arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton agammaglobulinemia tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G Cfd complement factor D (adipsin) ISO RGD PMID:10605043 RGD:1624328 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489 		JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 IMP RGD PMID:23470165 RGD:9068463 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III treatment ISO RGD PMID:10762218 RGD:9588604 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15283
    disease of anatomical entity 14933
      immune system disease 4189
        allergic disease 595
          hypersensitivity reaction type III disease 27
            arthus reaction 4
Path 2
Term Annotations click to browse term
  disease 15283
    disease of anatomical entity 14933
      Immune & Inflammatory Diseases 4797
        immune system disease 4189
          hypersensitivity reaction disease 155
            hypersensitivity reaction type III disease 27
              arthus reaction 4
paths to the root