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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:arthus reaction
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Accession:DOID:1556 term browser browse the term
Definition:A hypersensitivity reaction type III disease that is characterized by local vasculitis, has_symptom pain, edema, hemorrhage, or necrosis, and has_material_basis_in deposition of antigen-antibody immune complexes in vascular or serosal walls. (DO)
Synonyms:exact_synonym: arthus phenomenon;   arthus type urticaria
 primary_id: MESH:D001183
 xref: ICD10CM:T78.41;   ICD9CM:995.21;   NCI:C34400
For additional species annotation, visit the Alliance of Genome Resources.


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arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120
JBrowse link
G Cfd complement factor D ISO RGD PMID:10605043 RGD:1624328 NCBI chrNW_004955495:6,955,612...6,961,317 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23470165 RGD:9068463 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13435
    disease of anatomical entity 13169
      immune system disease 3741
        allergic disease 498
          hypersensitivity reaction type III disease 23
            arthus reaction 3
Path 2
Term Annotations click to browse term
  disease 13435
    disease of anatomical entity 13169
      Immune & Inflammatory Diseases 4239
        immune system disease 3741
          hypersensitivity reaction disease 132
            hypersensitivity reaction type III disease 23
              arthus reaction 3
paths to the root