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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:arthus reaction
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Accession:DOID:1556 term browser browse the term
Definition:A hypersensitivity reaction type III disease that is characterized by local vasculitis, has_symptom pain, edema, hemorrhage, or necrosis, and has_material_basis_in deposition of antigen-antibody immune complexes in vascular or serosal walls. (DO)
Synonyms:exact_synonym: arthus phenomenon;   arthus type urticaria
 primary_id: MESH:D001183
 xref: ICD10CM:T78.41;   ICD9CM:995.21;   NCI:C34400
For additional species annotation, visit the Alliance of Genome Resources.



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arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:90,551,874...90,588,786
Ensembl chr  X:100,684,017...100,725,187
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23470165 RGD:9068463 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa treatment ISO RGD PMID:10762218 RGD:9588604 NCBI chr 1:136,892,311...136,906,450 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14631
    disease of anatomical entity 14345
      immune system disease 4015
        allergic disease 559
          hypersensitivity reaction type III disease 25
            arthus reaction 3
Path 2
Term Annotations click to browse term
  disease 14631
    disease of anatomical entity 14345
      Immune & Inflammatory Diseases 4550
        immune system disease 4015
          hypersensitivity reaction disease 145
            hypersensitivity reaction type III disease 25
              arthus reaction 3
paths to the root