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Term:aggressive periodontitis
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Accession:DOID:1474 term browser browse the term
Definition:Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Synonyms:exact_synonym: JP;   JPD;   Juvenile Periodontitis;   PPP;   aggressive periodontitis, 1;   circumpubertal periodontitis;   early-onset periodontitis;   prepubertal periodontitis
 related_synonym: periodontoses, formerly;   periodontosis, formerly
 primary_id: MESH:D010520
 alt_id: OMIM:170650;   RDO:0006332
 xref: ICD10CM:K05.2
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aggressive periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:14398489
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8661707
G Ccr2 C-C motif chemokine receptor 2 RGD:8661707
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:5688299
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491835
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:7240710
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700939
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:14700939
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:14975139
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:8662884
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5147873
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:14975139
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:13592920

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    Stomatognathic Diseases 870
      tooth disease 241
        periodontal disease 103
          periodontitis 70
            aggressive periodontitis 13
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 14934
      nervous system disease 10239
        sensory system disease 4697
          mouth disease 680
            tooth disease 241
              periodontal disease 103
                periodontitis 70
                  aggressive periodontitis 13
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.